CN106692690A - Medicine composition for treating juvenile poliosis - Google Patents

Abstract

The invention provides a medicine composition for treating juvenile poliosis. The medicine composition is prepared from the following raw materials: 5 to 20 parts of fructus psoraleae, 5 to 20 parts of curculigo orchioides, 5 to 20 parts of herba ecliptae, 10 to 30 parts of semen astragali complanati, 10 to 30 parts of fructus rubi, 10 to 30 parts of Chinese wolfberry fruit, 10 to 30 parts of seed of Chinese dodder, 10 to 30 parts of mulberries, 20 to 40 parts of prepared rehmannia roots, 3 to 12 parts of cotton seeds, 3 to 12 parts of conic gymnadenia tuber, 3 to 12 parts of seville orange flower, 3 to 8 parts of omphalia, 3 to 8 parts of crinite uraria roots and 3 to 8 parts of lotus stamen. The medicine composition has the advantages that the recipe is rigorous; monarch medicine, minister medicine, assistant medicine and guide medicine are matched and combined to start from the root; the medicine is used according to indications; the curative effect is fast achieved; the effect is obvious; no toxic or side effects exist; the effect for treating the male juvenile poliosis is obvious.

Description

A kind of pharmaceutical composition for treating juvenile poliosis

【Technical field】

The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of pharmaceutical composition for treating juvenile poliosis.

【Background technology】

Determine hair color be in hair pigment granule number, hair is white by blacking, and the pigment of usually hair is thin Born of the same parents' deterioration, when decline when chromogenesis particle is unable to completely, hair just bleaches completely.Normal person since 35 years old, Trichochromes cell falls into a decline.And next year old of somebody 20 is just white, medically claim juvenile canities, be commonly called as " young person with greying hair ".It is modern Medical science thinks that the generation of young person with greying hair is more to be had with mental element, malnutrition, dysendocrinism and whole body chronic wasting disease Close.Traditional Chinese medicine then thinks, caused by this disease is mainly due to kidney deficiency and liver, deficiency of vital energy and blood.Geneogenous young person with greying hair, has with heredity more Close, be difficult treatment.And young person with greying hair posteriority, except according in addition to etiological treatment, should also strengthen nutrition.At present, China teenager White hair phenomenon is concentrated mainly on male, and is often accompanied by depilation phenomenon, just has 1 to face crown crisis in average every 5 males, Wherein male sex hormone hair loss patient accounts for the 95% of all alopecias, there are about 1.3 hundred million people.Therefore, young males take off to treatment white hair The hope of hair is the most urgent, therefore many teenagers or family members do not understand the true cause of alopecia and select kidney tonifying or purchase treatment The shampoo of white hair, medicine, cause to delay and control de- good opportunity, aggravation.

At present, teenager mainly has for treating the settling mode of white hair：1st, have hair dyed, but cure the symptoms, not the disease, and it is right Damaged in itself seriously in hair quality；2nd, hair transplant operation, there is wound, costly, is also to cure the symptoms, not the disease；3rd, medicine is administered, and is added with The shampoo or drug administration of medicine, medicine shampoo are only processed hair quality from outside, are cured the symptoms, not the disease；It is existing at present Oral type medicine, DeGrain, weak curative effect.

Drug regimen composition formula of the present invention is rigorous, all medicine phases of monarch are closed, and from root, suits the remedy to the case, curative effect is fast, Effect is obvious and has no toxic side effect, for treatment young males white hair effect is significant.

【The content of the invention】

In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of drug regimen for treating juvenile poliosis Thing, from root, is mainly used in treating young males white hair, and effect is significant, curative effect is fast, and has no toxic side effect.

A kind of technical scheme of the pharmaceutical composition for treating juvenile poliosis of the present invention is realized in：One kind treats green grass or young crops The pharmaceutical composition of juvenile canities, including following raw material：Psoralea corylifolia, thizoma curculiginis, Eclipta prostrata, semen astragali complanati, raspberry, the fruit of Chinese wolfberry, Tu Silk, mulberry fruit, cultivated land, levant cotton seed, conic gymnadenia tuber, bitter citrus immature flower, stone-like omphalia, crinite uraria root, stamen nelumbini.

Described pharmaceutical composition, in parts by weight, its component is：5~20 parts of Psoralea corylifolia, 5~20 parts of thizoma curculiginis, Eclipta prostrata 5 ~20 parts, 10~30 parts of semen astragali complanati, 10~30 parts of raspberry, 10~30 parts of the fruit of Chinese wolfberry, 10~30 parts of Semen Cuscutae, mulberry fruit 10~30 Part, 20~40 parts of cultivated land, 3~12 parts of levant cotton seed, 3~12 parts of conic gymnadenia tuber, 3~12 parts of bitter citrus immature flower, 3~8 parts of stone-like omphalia, crinite uraria root 3~8 parts, 3~8 parts of stamen nelumbini.

The weight portion of described pharmaceutical composition is preferably：8~14 parts of Psoralea corylifolia, 8~14 parts of thizoma curculiginis, 8~14 parts of Eclipta prostrata, 15~25 parts of semen astragali complanati, 15~25 parts of raspberry, 15~25 parts of the fruit of Chinese wolfberry, 15~25 parts of Semen Cuscutae, 15~25 parts of mulberry fruit, cultivated land 25~35 parts, 5~10 parts of levant cotton seed, 5~10 parts of conic gymnadenia tuber, 5~10 parts of bitter citrus immature flower, 5~10 parts of stone-like omphalia, crinite uraria root 5~10 Part, 3~6 parts of stamen nelumbini.

Optimum weight that the drug regimen is part is：10 parts of Psoralea corylifolia, 10 parts of thizoma curculiginis, 10 parts of Eclipta prostrata, semen astragali complanati 20 Part, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, 30 parts of cultivated land, 8 parts of levant cotton seed, 8 parts of conic gymnadenia tuber, turtle Turtle spend 8 parts, 7 parts of stone-like omphalia, 6 parts of crinite uraria root, 6 parts of stamen nelumbini.

Further, described composition is the preparation of peroral dosage form.

Think in traditional Chinese medicine, teenager " young person with greying hair " mainly there are following three kinds of reasons：Damage of kidney-YIN, ying blood abnormal heat, liver depression The stagnation of the circulation of vital energy.It can be seen that, hair and liver, kidney, qi and blood of people etc. have close relationship, and fully, hair can just have the blood supply of abundance to liver blood； Essence in kidney is the basic of human body, and the growth of hair, the maintenance of health status are all closely related with kidney.Therefore, the traditional Chinese medical science think as There is the early white phenomenon of white hair in fruit teenager, then show that liver blood kidney qi occurs in that decay, at this moment needs interior tune, dredges internal kidney qi not The problems such as foot, liver depression blood-head.

In addition, the psychologic research of modern medicine also found that the upset of mood can also make hair bleach.Because, Study and work is busy and cannot alleviate and loosen, be worried and overstrain one's nerves, soul the Psychological stimulation such as be upset all for a long time The blood vessel generation contracture of supply trichotrophy can be made, then hinder the function of the papilla manufacture melanin of hair root Hinder.Therefore, pharmaceutical composition of the present invention is controlled young males white hair from the traditional Chinese medical science and modern medicine from root Treat, suit the remedy to the case, curative effect is fast, effect is obvious and has no toxic side effect.

In medicament composing prescription of the present invention：

Psoralea corylifolia, also known as Hu fragrant-flowered garlic, the solid fat of mother-in-law, fructus psoaleae, Psoralen sparrow hawk, FRUCTUS PSORALEAE, Hu Guzi, Ji Guzi.Indication： Tonify the kidney and support yang.Control that kidney deficiency is cold to rush down, the enuresis, involuntary emission, frequent urination, impotence, waist and knee crymodynia, the cold of insufficiency type is breathed heavily and coughed.External application curing vitiligo.① 《Haigoushen》：" main man's Low Back Pain, the cold capsule of knee is wet, and stupid by all cold numbness, only small facility, cold in abdomen."②《Japan hanako materia medica》：It is " emerging Male sexuality, treating consumptive disease of cold nature, bright knowledge."③《Kaibao Bencao》：" main general debility, wind void is cold, and marrow wound loses, and the cold essence of kidney flows and married woman's blood Gas is had an abortion."④《Product converge essence will》：" solid essence."⑤《Detailed outline》：" the kidney type diarrhea is controlled, leads to the gate of vitality, warm up public region, hold back spirit."⑥《Beautiful Chinese catalpa Medicine solution》：" warm water and soil, digests diet, rises and reaches taste, convergence lingering diarrhea, seminal emission, under band, many, just sliding all cards of drowning."⑦《Medical center is compiled Will》：" control the cold of insufficiency type and breathe heavily and cough."

Thizoma curculiginis, containing tannin 4%, fatty 1% and resin, starch etc..Indication：Warm kidney sun, strengthens the bone.Control impotence essence It is cold, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula, the deficiency of yang is cold to rush down.①《Haiyao Bencao, Oversea Materia Medica》：" main wind is mended warm Waist pin, clear five viscera settling, strengthening the bones and muscles helps digestion." " is declared and is mended again, main husband's seven kinds of impairments, bright knowledge, beneficial biceps, fills out marrow, Yiyang."② 《Japan hanako materia medica》：" all general mood are controlled, general debility, appetizer under the gas is mended."③《Kaibao Bencao》：" main trusted subordinate's cold air can not be eaten, The air-cooled contraction numbness of waist pin can not go, husband's consumptive disease, and old man loses and drowns."④《The southern regions of the Yunnan Province book on Chinese herbal medicine》：" control that married woman is red to collapse lower blood, attack ulcer, arrange Purulence."⑤《The sward property of medicine is standby will》：" gonorrhoea is controlled in kidney tonifying, analgesic, manages convulsive seizure due to phlegm-fire, and pot is carnivorous.Ten steam nine shines, and is hidden with granulated sugar, morning Tea send, and can strengthen spirit, black beard and hair."

Eclipta prostrata, also known as Eclipta prostrata, black tobacco.Indication：Nourishing liver and kidney, cooling blood and hemostasis, can control various haematemesis, and nose goes out The diseases such as blood, hemoptysis, enterorrhagia, hematuria, hemorrhoid hemorrhage, metrorrhagia.Smash juice and apply eyebrow hair, hair growth can be promoted, it is for oral administration to have black hair, black Hair effect.《Tang materia medica》：" main bloody flux, acupuncture sore hair, big vast blood can not the person of stopping respect it ".《Japan hanako materia medica》：" apocenosis, hemostasis are led to Small intestine, applies all sores and silkworm Guo ".《The southern regions of the Yunnan Province book on Chinese herbal medicine》：" permanent tooth, black hair wash nine kinds of hemorrhoid ".《Compendium of Materia Medica》：" black beard and hair, benefit Kidney yin ".《Book on Chinese herbal medicine is stated》：" treat excessive blood and kidney deficiency be changed into stranguria caused by overstrain ".

Semen astragali complanati, indication：Tonifying liver, kidney-nourishing, improving eyesight, controlling nocturnal emission with astringent drugs.Kidney deficiency and liver is controlled, soreness of waist and knee joint, blurred vision, seminal emission is early Let out, frequent urination, the enuresis, hematuria, leukorrhea.①《Amplification on Materia Medica》：" kidney tonifying."②《Detailed outline》：" kidney tonifying, controls pain in the back and lets out essence, deficient It is tired."③《The new compilation of materia medica》：" kidney tonifying, Qiang Yin, strengthening the essence, improving eyesight.Control under band, anal fistula, cloudy Huang.Performance controlling nocturnal emission with astringent drugs."④《Medical center is compiled Will》：" hard kidney water, rushes down evil wet , Qu Disorder lump in the abdomen hemorrhoid complicated by anal fistulas."⑤《Mirror can about be cured》：" drip is only lost, hematuria reduces just."⑥《Book on Chinese herbal medicine is asked It is former》：" consumptive lung disease is controlled, kidney is cold, urinate many, lost and drown, improving eyesight, muscle long.Also control liver kidney wind toxin and attack note."

Raspberry, also known as basin, black Fischer, small pallet, Shan Pao, Jin Fischer are covered, Rubus chingii is containing organic acid, carbohydrate and lacks Amount vitamin C.Indication：Filling liver kidney, reduces just, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight.Impotence is controlled, is passed out semen, number of urinating is lost and drowned, consumptive disease, mesh Secretly.①《Do not record》：" main QI invigorating is made light of one's life by commiting suicide, and order hair is not white."②《Haigoushen》：" main man's kidney-jing deficiency exhausts, and woman's food has son.It is main Impotence."③《Japan hanako materia medica》：" five viscera settling, beneficial color support vital essence, long hair, Qiang Zhi.Treat apoplexy body hot and frightened."④《Open treasured Book on Chinese herbal medicine》：" qi-restoratives is continuous exhausted, and strong cloudy Jianyang, smoothing skin is pacified and internal organs, and middle benefit gas benefit power treats strain wind void, nourishing liver and improving eyesight."⑤ 《Amplification on Materia Medica》：" kidney-nourishing is dirty, reduces just."⑥《Book on Chinese herbal medicine covers bamboo fish trap》：" control kidney hinder essence exhaust it is fluent."⑦《Book on Chinese herbal medicine is stated》：" control overstrain, Consumptive disease, liver kidney qi deficiency aversion to cold, kidney qi deficiency is against cough, impotence, disappear illness, diarrhea, reddish and whitish turbid urine, and the arthroncus of knee is all to see blood trouble and mesh disease."

The fruit of Chinese wolfberry, rich in carrotene, LBP-X, monose, glycine betaine, aliphatic acid, proteins and peptides, vitamin B1, Vitamin B2, vitamin B6, vitamin C, 18 kinds of amino acid (containing 8 kinds of essential amino acids), trace element (calcium, zinc, magnesium, iron, Manganese, phosphorus etc.).Indication：Nourishing liver and kidney, strengthening the essence blood-nourishing, improving eyesight disappears screen, moistens the lung and relieve the cough.Cure mainly the kidney deficiency atrophic debility of bones, impotence and seminal emission, Long infertility, senilism early ageing, poliosis, blood deficiency chlorosis, postpartum breast is few, and mesh is secretly failed to understand, interior external opculopathy eye, Heat Diabetes, labor heat The diseases such as hectic fever due to yin, tuberculosis cough, the few phlegm of dry cough.

Semen Cuscutae, indication：Filling liver kidney, benefiting quintessence, improving eyesight.Soreness of waist and knee joint is controlled, is passed out semen, quenched one's thirst, dripping urination, mesh Secretly.①《This warp》：" main continuous wound absolutely, tonifying for the deficiency, QI invigorating power, the strong people of fertilizer, long term usage improving eyesight."②《Lei Gong Pao Zhi Lun》：" mend artificial satellite Gas, tendon and vessel of helping others."③《Do not record》：" support flesh cloudy by force, hard muscles and bones, stem syncope due to pathogenic cold, essence is excessive to have the heeltap from going out, and bitter taste is dry thirsty, blood of trembling with fear It is product."④《Haigoushen》：" control man's woman's void cold, sperm adding and marrow healthing goes Low Back Pain knee cold, master quenches one's thirst and hankers again."⑤《Solar corona Book on Chinese herbal medicine》：" general debility is mended, is controlled and is let out essence, hematuria, embellish lung." 6. king accounts for well：" the dirty wind of tonifying liver is empty."

Mulberry fruit, indication：Liver-kidney Yin deficiency is controlled, is quenched one's thirst, constipation, mesh is dark, tinnitus, scrofula, articular instability.①《Book on Chinese herbal medicine spreads out Justice》：" control hot thirsty, production of sperm god, and small intestine heat."②《The southern regions of the Yunnan Province book on Chinese herbal medicine》：" kidney-nourishing is dirty and controlling nocturnal emission with astringent drugs, long term usage dark hair improving eyesight.”

Cultivated land, also known as prepared rhizome of rehmannia.Glutinous rehmannia is Scrophulariaceae, glutinous rehmannia platymiscium, and the processed processing of root tuber of glutinous rehmannia is formed.Generally It is auxiliary material through steaming solarization repeatedly with wine, fructus amomi, dried orange peel, to interior exogenic color dirty oil profit, soft texture is sticky.Section is used, or fries charcoal use.Through After processing, the property of medicine turns tepor by being slightly cold, and help strengthens,《This is through meeting original》：" prepared rhizome of rehmannia, false firepower steams and shines, and it is sweet to turn hardship, is The yang aspect of yin, therefore vigour in energy kidney tonifying.”《Detailed outline》：" fill out marrow, muscle long, promoting vital essence and blood genernation, tonifying five zang organs, internal injury are not enough, promoting blood circulation, Sharp knowledge, black beard and hair, man's general debility, threatened abortion in woman's wound, irregular menorrhea, tire produces all kinds of diseases and ailments ".

Levant cotton seed, indication：Warm kidney, qi-restoratives, hemostasis.Control impotence, the testis swelling and hanging down of either of the testes, the enuresis.Hemorrhoid blood, prolapse of the anus, uterine bleeding, band Under.①《This is through meeting original》：" charred medicinal herb with its property retained, solves plum sore, and anal fistula, prolapse of the anus, lower blood often takes half two, and black soya bean drenches wine and takes it."②《Medicine Property is examined》：" qi-restoratives, warms up waist, controls damage."③《Modern Practical Chinese medicinal》：" there is the effect for promoting breast milk secretion."④《Conventional herbal medicine among the people Compilation》：" warm kidney, analgesic.Leukorrhea is controlled, and controls infantile enuresis."

Conic gymnadenia tuber, indication：Tonifying Qi and blood, promotes the production of body fluid to quench thirst.Deficiency syndrome of the lung cough and asthma is controlled, consumptive disease is become thin, neurasthenia, chronic diarrhea, Lose blood, under band, breast is few, chronic hepatitis.①《Northeast medicine plants will》：" mucus is made, under being poisoned and rushing down；Steep in wine as strong, strong Smart agent."②《Shanxi Chinese medicinal herbal》：" astringing to arrest bleeding, removing toxic substances.Control chronic diarrhea to lose blood, gonorrhoea, under band."③《During Heilungkiang is among the people Medicine》：" steep in wine and control impotence."④《Middle traditional Chinese medicines plant illustrated handbook》：" dispersing blood stasis.Traumatic injury is controlled, hematocele is not all right."⑤《Often use medium-height grass in Sichuan Medicine》：" blood yiqi promotes the production of body fluid to quench thirst.Deficiency syndrome of the lung cough and asthma is controlled, consumptive disease is thin thin, hypogalactia juice."⑥《Often use Chinese herbal medicine in Tibet》：" control chronic Hepatitis."⑦《Shaanxi Chinese herbal medicine》：" strengthening by means of tonics, tonifying spleen moistening lung are calmed the nerves relieving convulsion, QI invigorating analgesic.Control in poor health, nerve declines It is weak, internal lesion caused by overexertion, cough, asthma."

Bitter citrus immature flower, indication：It is soothing the liver, and stomach, qi-regulating.Control ruffian in the heart vexed, abdominal distention, vomiting, few food.①《Medicine materical crude slice New ginseng》：" qi-regulating chest wide, whet the appetite preventing or arresting vomiting."②《Animals and plants Folk medicine》：" stomachache is controlled, is had a stomachache."③《Zhejiang Chinese medicine handbook》：" adjust Gas is soothing the liver.Control chest diaphragm and gastral cavity space ruffian bitterly."

Stone-like omphalia, indication：Disperse accumulations, desinsection.Control abdominal pain due to enterositosis, infantile malnutrition due to digestive disturbances or intestinalparasites disease, wind epilepsy.①《This warp》：" master kills three worms, by poison Gas, pathogenic heat in the stomach, sharp husband, unfavorable woman, rub cream, except children's all kinds of diseases and ailments."②《Do not record》：" by perverse trend, foul wind sweating, in allowancing for bark Heat, knot product, it is white worm, very little white more than from going out."③《Haigoushen》：" can by wind, main epilepsy it is mad walk, kill roundworm."④《Beautiful Chinese catalpa medicine Solution》：" heat-clearing is soothing the liver, kills pinworm, and body wind removes epilepsy, only children's sweat."⑤《Shaanxi Chinese medicinal herbal》：" disperse accumulations desinsection, it is clearing heat and detoxicating. Abdominal pain due to enterositosis is controlled, infantile malnutrition, pathogenic heat in the stomach is more significant to taeniasis curative effect."

Crinite uraria root, indication：Qi-regulating, resolving sputum, kidney-nourishing.Control heart peratodynia, phlegmatic cough, emission due to the kidney deficiency.①《Guangxi Chinese medicinal herbal》：" promoting qi circulation and relieving pain, by phlegmization drink.Control heart peratodynia, phlegmatic cough."②《Quanzhou book on Chinese herbal medicine》：" kidney-nourishing nourishing liver.Control kidney deficiency Seminal emission."

Stamen nelumbini, mainly containing Quercetin, cyanidenon, Isoquercitrin, cyanidenon glycoside.Indication：Clear away heart-fire, benefit Kidney, puckery essence, hemostasis.Nocturnal emission lingering diarrhea is controlled, told, be defeated in battle, collapsing, band, rush down dysentery.①《Book on Chinese herbal medicine covers bamboo fish trap》：" kidney-nourishing, puckery essence, Gu marrow."②《Guiding principle Mesh》：" clear away heart-fire logical kidney, solid essence, black beard and hair, pleases color, and beneficial blood, hemostasis is collapsed, spits blood."③《Explaining abstruseness of the canon of materia medica》：" control man's kidney Let out, woman collapses band."④《Mirror can about be cured》：" remove rush down dysentery."⑤《Book on Chinese herbal medicine is new again》：" abnormal heat of the lung that clears away heart-fire, relieving summer-heat relieving restlessness, promotes the production of body fluid only Yearningly."

Pharmaceutical composition of the present invention is the composite formula drawn under the guidance of traditional Chinese medical theory and modern medicine research. According to the principles of formulating prescriptions of traditional Chinese medical science monarch, the present invention chooses raspberry, the fruit of Chinese wolfberry, Semen Cuscutae, mulberry fruit, cultivated land as monarch drug in a prescription, There is nourishing liver and kidney, strengthening the essence blood-nourishing, relieving psychological pressure, and nutritious, in hebetic teenager its His aspect is nursed one's health very benefits；Using Psoralea corylifolia, thizoma curculiginis, Eclipta prostrata as ministerial drug, with kidney deficiency of tonifying the kidney and support yang, control it is cold rush down, Strengthen the bone, cooling blood and hemostasis the effects such as, be mainly used in aid in monarch drug in a prescription, nurse one's health monarch drug in a prescription deficiency；With levant cotton seed, conic gymnadenia tuber, bitter citrus immature flower It is monarch drug in a prescription ministerial drug promotion of blood circulation the effects such as with soothing the liver and stomach, qi-regulating, regulating the qi flowing in the channels is soothing the liver, improves effect as adjutant；With thunder Ball, crinite uraria root, stamen nelumbini as making medicine, the effects such as with by perverse trend, heat-clearing is soothing the liver removing toxic substances, resolving sputum.From the research of modern medicine, Pharmaceutical composition of the present invention has functions that calm the nerves relieving convulsion, alleviation pressure, dredging hair blood vessel.Drug regimen composition formula of the present invention The all medicine phases of rigorous, monarch are closed, and from root, are suited the remedy to the case, and curative effect is fast, effect is obvious and has no toxic side effect, for controlling Treat young males white hair effect is significant.

【Specific embodiment】

The following examples can help those skilled in the art that the present invention is more completely understood, but cannot be with any Mode limits the present invention.

Embodiment 1：

A kind of pharmaceutical composition for treating juvenile poliosis, including following raw material：5 parts of Psoralea corylifolia, 20 parts of thizoma curculiginis, Eclipta prostrata 5 parts, 30 parts of semen astragali complanati, 30 parts of raspberry, 10 parts of the fruit of Chinese wolfberry, 30 parts of Semen Cuscutae, 20 parts of mulberry fruit, 20 parts of cultivated land, 3 parts of levant cotton seed, 3 parts of conic gymnadenia tuber, 3 parts of bitter citrus immature flower, 8 parts of stone-like omphalia, 8 parts of crinite uraria root, 3 parts of stamen nelumbini.

Preparation method：All raw materials are placed in glass wine vat, the rice wine that 8kg alcoholic strengthes are not less than 55 degree is subsequently adding, Soaked 1 month after sealing, medicinal liquor formulation is obtained.

Embodiment 2：

A kind of pharmaceutical composition for treating juvenile poliosis, including following raw material：20 parts of Psoralea corylifolia, 5 parts of thizoma curculiginis, Eclipta prostrata 20 parts, 10 parts of semen astragali complanati, 30 parts of raspberry, 15 parts of the fruit of Chinese wolfberry, 10 parts of Semen Cuscutae, 30 parts of mulberry fruit, 40 parts of cultivated land, levant cotton seed 12 Part, 12 parts of conic gymnadenia tuber, 3 parts of bitter citrus immature flower, 3 parts of stone-like omphalia, 3 parts of crinite uraria root, 8 parts of stamen nelumbini.

Above-mentioned Chinese medicine is dried and crushed into fine powder, is sieved, mixed, load hard softgel shell, 0.5g/, the present invention is obtained Pharmaceutical composition.

Embodiment 3：

A kind of pharmaceutical composition for treating juvenile poliosis, including following raw material：8 parts of Psoralea corylifolia, 8 parts of thizoma curculiginis, Eclipta prostrata 14 parts, 15 parts of semen astragali complanati, 15 parts of raspberry, 25 parts of the fruit of Chinese wolfberry, 25 parts of Semen Cuscutae, 25 parts of mulberry fruit, 35 parts of cultivated land, 5 parts of levant cotton seed, 10 parts of conic gymnadenia tuber, 5 parts of bitter citrus immature flower, 10 parts of stone-like omphalia, 10 parts of crinite uraria root, 3 parts of stamen nelumbini.

Preparation method：Above-mentioned Chinese medicine is dried and crushed into meal, the ethanol with concentration as 50-60% be solvent 60~ 70 DEG C of refluxing extractions, low temperature is condensed into thick medicinal extract after extract solution removal ethanol, dry, pulverize into fine powder, sieves, and mixes, granulation, It is tabletted, 0.5g/ pieces.

Embodiment 4：

A kind of pharmaceutical composition for treating juvenile poliosis, including following raw material：14 parts of Psoralea corylifolia, 14 parts of thizoma curculiginis, non-irrigated lotus 8 parts of grass, 25 parts of semen astragali complanati, 25 parts of raspberry, 15 parts of the fruit of Chinese wolfberry, 15 parts of Semen Cuscutae, 25 parts of mulberry fruit, 25 parts of cultivated land, levant cotton seed 10 Part, 5 parts of conic gymnadenia tuber, 10 parts of bitter citrus immature flower, 5 parts of stone-like omphalia, 5 parts of crinite uraria root, 6 parts of stamen nelumbini.

Preparation method：Said medicine is smash thin altogether, is then store with calico bag, be placed in net device, steeping in wine removes slag after 7 days and takes juice It is standby.

Embodiment 5：

A kind of pharmaceutical composition for treating juvenile poliosis, including following raw material：10 parts of Psoralea corylifolia, 10 parts of thizoma curculiginis, non-irrigated lotus 10 parts of grass, 20 parts of semen astragali complanati, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, 30 parts of cultivated land, levant cotton seed 8 Part, 8 parts of conic gymnadenia tuber, 8 parts of bitter citrus immature flower, 7 parts of stone-like omphalia, 6 parts of crinite uraria root, 6 parts of stamen nelumbini.

Preparation method：After getting raw material ready in proportion, add the decocting of 1.5kg to boil, decoction liquor is filtered, obtain solution, will Resulting solution is concentrated to give medicinal extract 1.2kg, and the concentration that then gained medicinal extract is dissolved in 8kg is water-soluble according to the ethanol of weight meter 95% In liquid, stirring mixing, quantitative separating obtains oral liquid formulations.

The medicine prepared in 1~embodiment of embodiment 5 is directly used in for oral administration.

Toxicity test：

Experiment prepares：This experiment uses mouse 100, and Chinese medicine composition prepared by embodiment 5 is dissolved in into sterile physiological In salt solution, solution gavage is configured to.If 0g, 20g, 30g, 40g, 50g crude drug/kg dosage groups, continuously give to mouse gavage respectively Medicine 12 weeks, observes influence of each dosage group to mouse indices.

Result of the test：Body weight, food ration, peripheral hemogram, clotting time, electrocardio of the Chinese medicine composition of the invention to rat Figure, organ index etc. have no significant effect；The binomial index determining result of blood biochemical ten, is administered 12 weeks 20g crude drugs/kg dosage groups BiLi values are higher than control group (P<0.05)；20g crude drugs/kg dosage groups, 30g crude drugs/kg dosage group TP values are higher than control group (P< 0.05), but within normal physiologic range, other indexs compare no significant difference with control group.Convalescence, each administration group was each Item index determining value compares equal no significant difference with control group.Each internal organs gross examination of skeletal muscle no abnormality seen of each group.

Contrast test：

Experiment prepares：Experimental group, control group 1~4 are respectively applied to clinical observation case, every group has patient 72, And it is young males patient.Each group patient is in average age, the course of disease, the state of an illness without significant difference.

(1) experimental group：The oral liquid formulations that embodiment 5 is prepared.

(2) control group 1：The oral liquid formulations prepared using following raw material：10 parts of Psoralea corylifolia, 10 parts of thizoma curculiginis, non-irrigated lotus 10 parts of grass, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, 30 parts of cultivated land, 6 parts of stamen nelumbini.

Its preparation method is identical with embodiment 5.

(3) control group 2：The oral liquid formulations prepared using following raw material：10 parts of Psoralea corylifolia, 10 parts of thizoma curculiginis, non-irrigated lotus 10 parts of grass, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, 30 parts of cultivated land, 8 parts of levant cotton seed, conic gymnadenia tuber 8 Part, 6 parts of crinite uraria root, 6 parts of stamen nelumbini.Its preparation method is identical with embodiment 5.

(4) control group 3：The oral liquid formulations prepared using following raw material：10 parts of Psoralea corylifolia, 10 parts of thizoma curculiginis, non-irrigated lotus Grass 10 parts, 20 parts of semen astragali complanati, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, 30 parts of cultivated land, 7 parts of stone-like omphalia, 6 parts of crinite uraria root, 6 parts of stamen nelumbini.Its preparation method is identical with embodiment 5.

(5) control group 4：The oral liquid formulations prepared using following raw material：10 parts of Psoralea corylifolia, 10 parts of thizoma curculiginis, non-irrigated lotus 10 parts of grass, 20 parts of semen astragali complanati, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, 30 parts of cultivated land, levant cotton seed 8 Part, 8 parts of conic gymnadenia tuber, 8 parts of bitter citrus immature flower, 6 parts of stamen nelumbini.Its preparation method is identical with embodiment 5.

Method of administration：15 milliliters every time, 3 times a day.It is within one month a course for the treatment of, its 3 course for the treatment of of treatment, after the course for the treatment of terminates Whether observation has repeatedly for 1 year.

Therapeutic evaluation：

As can be seen from the above table：After taking 3 courses for the treatment of, substantially, white hair is obviously improved situation to experimental group white hair therapeutic effect Most preferably, and recurrence probability is very low；The white hair improvement situation effect of control group 1 is worst, and recurrence probability is higher；Control group 2 Substantially, recurrence probability is also low, but compared with experimental group, its curative effect cycle is more long for white hair therapeutic effect；The white hair of control group 3 is treated Effect is obvious, but its recurrence probability is higher compared with experimental group 1；The white hair therapeutic effect of control group 4 substantially, but recurrence probability compared with It is high.

Experiment material：The clinical efficacy of pharmaceutical composition of the present invention.

1st, physical data：In the case where patient is voluntary, this pharmaceutical composition is applied to the total male of clinical observation case Minimum 14 years old of patient 210, wherein age, it is maximum 33 years old, two groups of patients in average age, the course of disease, the state of an illness without significant difference,

Its specific distribution is as follows：

2nd, diagnostic criteria

Slight young person with greying hair：There is a small amount of white hair in hair, hair is with a small amount of dandruff.

Moderate young person with greying hair：White hair amount is more, and black and white is mixed, dry hair, dimness, when be often accompanied by the symptom of itching of the scalp.

Severe young person with greying hair：White hair rate reaches 70% or so, or even visible hair sparse comes off, and some patients are also with dizziness Dim eyesight, soreness and weakness of waist and knees, lassitude, insomnia and dreamful sleep or the symptom such as counts accurately at deficient and stringy pulse.

3rd, method of administration and the course for the treatment of：

The oral liquid formulations of the preparation of embodiment 5 are taken, 15 milliliters every time, 3 times a day；

The tablet of the preparation of embodiment 3 is taken, 4 tablets once, and 3 times a day.

The medicinal liquor of the preparation of embodiment 1 is taken, 10 milliliters every time, 3 times a day；

It is within one month a course for the treatment of, its 2~4 course for the treatment of of treatment.2 courses for the treatment of of this test of cure.

4th, efficacy determination：According to white hair improve situation, be divided into white hair be obviously improved, white hair improve, it is invalid.

5th, therapeutic evaluation：

5 pairs of clinical observations for the treatment of juvenile poliosis of embodiment

Number of cases	White hair is obviously improved	White hair is obviously improved	It is invalid	Total effective rate
					70	42	23	5	92.9%

3 pairs of clinical observations for the treatment of juvenile poliosis of embodiment

Number of cases	White hair is obviously improved	White hair is obviously improved	It is invalid	Total effective rate
					70	35	29	6	91.4%

1 pair of clinical observation for the treatment of juvenile poliosis of embodiment

Number of cases	White hair is obviously improved	White hair is obviously improved	It is invalid	Total effective rate
					70	38	26	6	91.4%

Medicine composite for curing effect of the present invention can be seen that substantially by three above form, to young males white hair Clearly, curative effect is fast for improvement, efficient high.

Typical case：

Zhang, 26 years old, man, Out-migrant for work was big due to operating pressure, and mental burden weight makes dark hair bleach, through each medical treatment Single therapeutic is invalid, takes 3 courses for the treatment of orally using the prescription of the embodiment of the present invention 5 after being introduced, and dark hair substantially grows, 4 treatments Cure after journey, maintained one month again afterwards, return to one's perfect health.

Bai, 19 years old, juvenile canities, through many treat after it is invalid, thought is sorely distressed, to going to school he bring huge Big stress, afterwards the practical present invention implement 2 prescription and taken 5 courses for the treatment of, white hair blackening.

Lee, 30, because sick medication causes white hair, after having taken 2 courses for the treatment of using the prescription of the embodiment of the present invention 1 later, Dark hair is born, continues to take 3 courses for the treatment of, fully recovered.

Wang, 17 years old, man, senior middle school finds oneself to turn white more and more in period, and more very, hair fragility is easily broken for scalp itch, The scattered alopecia of overhead, do one's utmost later adjustment work and rest and psychological pressure, but effect is very little, uses the embodiment of the present invention 5 Prescription takes 5 courses for the treatment of orally, and depilation phenomenon is disappeared, and white hair is significantly reduced, and the symptom of dandruff and itch is also eliminated.

Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that：Not Depart from and can these embodiments be carried out with various changes, modification, replacement and modification under principle of the invention and objective, it is of the invention Scope is limited by claim and its equivalent.

Claims (5)

1. a kind of pharmaceutical composition for treating juvenile poliosis, it is characterised in that including following raw material：Psoralea corylifolia, thizoma curculiginis, non-irrigated lotus Grass, semen astragali complanati, raspberry, the fruit of Chinese wolfberry, Semen Cuscutae, mulberry fruit, cultivated land, levant cotton seed, conic gymnadenia tuber, bitter citrus immature flower, stone-like omphalia, crinite uraria root, Stamen nelumbini.

2. pharmaceutical composition as claimed in claim 1, it is characterised in that in parts by weight, its component is：Psoralea corylifolia 5~20 Part, 5~20 parts of thizoma curculiginis, 5~20 parts of Eclipta prostrata, 10~30 parts of semen astragali complanati, 10~30 parts of raspberry, 10~30 parts of the fruit of Chinese wolfberry, Tu 10~30 parts of silk, 10~30 parts of mulberry fruit, 20~40 parts of cultivated land, 3~12 parts of levant cotton seed, 3~12 parts of conic gymnadenia tuber, bitter citrus immature flower 3~ 12 parts, 3~8 parts of stone-like omphalia, 3~8 parts of crinite uraria root, 3~8 parts of stamen nelumbini.

3. pharmaceutical composition as claimed in claim 2, it is characterised in that the weight portion of the component is：Psoralea corylifolia 8~14 Part, 8~14 parts of thizoma curculiginis, 8~14 parts of Eclipta prostrata, 15~25 parts of semen astragali complanati, 15~25 parts of raspberry, 15~25 parts of the fruit of Chinese wolfberry, Tu 15~25 parts of silk, 15~25 parts of mulberry fruit, 25~35 parts of cultivated land, 5~10 parts of levant cotton seed, 5~10 parts of conic gymnadenia tuber, bitter citrus immature flower 5~ 10 parts, 5~10 parts of stone-like omphalia, 5~10 parts of crinite uraria root, 3~6 parts of stamen nelumbini.

4. pharmaceutical composition as claimed in claim 3, it is characterised in that the weight portion of the component is：10 parts of Psoralea corylifolia, thizoma curculiginis 10 parts, 10 parts of Eclipta prostrata, 20 parts of semen astragali complanati, 20 parts of raspberry, 20 parts of the fruit of Chinese wolfberry, 20 parts of Semen Cuscutae, 20 parts of mulberry fruit, cultivated land 30 Part, 8 parts of levant cotton seed, 8 parts of conic gymnadenia tuber, 8 parts of bitter citrus immature flower, 7 parts of stone-like omphalia, 6 parts of crinite uraria root, 6 parts of stamen nelumbini.

5. the pharmaceutical composition as described in Claims 1 to 4 is any, it is characterised in that described composition is peroral dosage form Preparation.