CN104721553A - Oral medicine for treating allergic rhinitis - Google Patents

Oral medicine for treating allergic rhinitis Download PDF

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CN104721553A
CN104721553A CN201510172407.7A CN201510172407A CN104721553A CN 104721553 A CN104721553 A CN 104721553A CN 201510172407 A CN201510172407 A CN 201510172407A CN 104721553 A CN104721553 A CN 104721553A
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radix
fructus
rhizoma
allergic rhinitis
herba
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李辉
高玉萍
于子旭
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Shandong Provincial Hospital
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Shandong Provincial Hospital
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Abstract

The invention discloses an oral medicine for treating allergic rhinitis. The oral medicine for treating the allergic rhinitis is prepared from radix codonopsis, radix astragali, prepared rehmannia roots, polygonatum kingianum, schisandra chinensis, manyprickle acanthopanax roots, common yam rhizome, gecko, lily, aster tataricus, platycodon grandiflorum, desertliving cistanche, fructus lycii, pulp of cornus, poria cocos, white atractylodes rhizome, citrus, hippophae rhamnoides, white peony roots, finger citron, hawthorn fruits, liquorice, angelica sinensis, corydalis yanhusuo, achyranthes bidentata, cassia bark, monkshood, tenuifolia, radix angelica dahurica, centipeda minima and fructus xanthii. The oral medicine prepared according to the traditional Chinese medicine formula is capable of effectively treating the allergic rhinitis, and the total effective rate is up to 100%.

Description

A kind of oral medicine for the treatment of of allergic rhinitis
Technical field
The present invention relates to a kind of oral medicine for the treatment of of allergic rhinitis, belong to medical art.
Background technology
Allergic rhinitis and allergic rhinitis, after referring to atopic individuals contact allergen, primarily of medium (mainly histamine) release of IgE mediation, and have the nasal mucosa non-infectious inflammatory disease that panimmunity competent cell and cytokine etc. participate in.Its essential condition occurred has 3: namely specific antigen causes the material of organism immune response; Atopic individuals and so-called individual variation, allergic constitution; Specific antigen and spy answer both type individualities to meet.Classical symptom mainly paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and the rhinocnesmus of allergic rhinitis, part is with hyposmia.Very harmful to health of allergic rhinitis.It can cause headache, and dizzy, insomnia is forgotten, upsets, and flies into a rage easily, and student learning achievement progressively declines, sleepiness is indifferent, and power of noticing is not concentrated.Allergic rhinitis are global health problem, also can cause numerous disease and disability.
At present, the medicine that allergic rhinitis is common has: antihistaminic oral or nose 2nd generation or novel H1 antihistaminic, glucocorticoid, chromone class medicine etc.Said medicine mainly plays the object alleviating the symptoms such as rhinocnesmus, sneeze and watery nasal discharge, can not from treatment of allergic rhinitis root.Simultaneously owing to not effecting a radical cure, need long-term, Reusability, easily produce drug resistance and certain side effect.
Summary of the invention
Instant invention overcomes above-mentioned the deficiencies in the prior art, provide a kind of oral medicine for the treatment of of allergic rhinitis.This medicine, can effective treatment of allergic rhinitis with pure Chinese prescription.
Technical scheme of the present invention is: a kind of oral medicine for the treatment of of allergic rhinitis, it is characterized in that, be made up of the crude drug of following weight: Radix Codonopsis 12-18g, Radix Astragali 12-18g, Radix Rehmanniae Preparata 8-12g, Rhizoma Polygonati 10-15g, Fructus Schisandrae Chinensis 5-8g, Radix Et Caulis Acanthopanacis Senticosi 5-10g, Rhizoma Dioscoreae 8-12g, Gecko 3-8g, Bulbus Lilii 3-8g, Radix Asteris 3-8g, Radix Platycodonis 3-8g, Herba Cistanches 10-15g, Fructus Lycii 8-12g, Fructus Corni 5-10g, Poria 5-10g, Rhizoma Atractylodis Macrocephalae 10-15g, Pericarpium Citri Reticulatae 5-10g, Fructus Hippophae 3-8g, Radix Paeoniae Alba 3-8g, Fructus Citri Sarcodactylis 3-8g, Fructus Crataegi 5-10g, Radix Glycyrrhizae 3-8g, Radix Angelicae Sinensis 5-15g, Rhizoma Corydalis 5-12g, Radix Achyranthis Bidentatae 3-10g, Cortex Cinnamomi 1-12g, Radix Aconiti Lateralis Preparata 1-10g, Herba Schizonepetae 1-18g, Radix Angelicae Dahuricae 1-10g, Herba Centipedae 1-15g and Fructus Xanthii 1-10g.
Preferably, the proportioning taken when early stage, the symptom such as nasal obstruction, watery nasal discharge was heavier is: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 12g, Rhizoma Corydalis 10g, Radix Achyranthis Bidentatae 8g, Cortex Cinnamomi 10g, Radix Aconiti Lateralis Preparata 8g, Herba Schizonepetae 15g, Radix Angelicae Dahuricae 10g, Herba Centipedae 15g and Fructus Xanthii 10g.
Preferably, take the symptoms such as nasal obstruction in mid-term, watery nasal discharge lighter time proportioning be: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 8g, Radix Achyranthis Bidentatae 6g, Cortex Cinnamomi 5g, Radix Aconiti Lateralis Preparata 3g, Herba Schizonepetae 5g, Radix Angelicae Dahuricae 3g, Herba Centipedae 3g and Fructus Xanthii 3g.
Preferably, the proportioning taken when the symptoms such as later stage nasal obstruction, watery nasal discharge almost do not have is: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 8g, Radix Achyranthis Bidentatae 3g, Cortex Cinnamomi 2g, Radix Aconiti Lateralis Preparata 1g, Herba Schizonepetae 1g, Radix Angelicae Dahuricae 1g, Herba Centipedae 1g and Fructus Xanthii 1g.
Preparation and instructions of taking: soak by water, every day, potion, took at twice sooner or later.Within 7 days, be 1 course for the treatment of, general 1-4 can cure a course for the treatment of.Take early stage when having a stuffy nose serious, suitably can use the nasal formulations alleviating the symptoms such as nasal obstruction, watery nasal discharge, as compound furacilin nasal drops etc.
Above-mentioned raw materials medicine can also add various customary adjuvant required when preparing different dosage form further, oral formulations is commonly used, as made granule, pill, capsule, tablet etc. as excipient, correctives, binding agent etc. are prepared into any one with the method for Chinese medicinal of routine.
Each Chinese medicine effect:
Radix Codonopsis: sweet is flat.Return spleen, lung meridian.Function with cure mainly: spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.Function with cure mainly: YIN nourishing of enriching blood, beneficial essence fills out marrow.For blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, dizzy, tinnitus, early whitening of beard and hair.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.Function with cure mainly: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis, asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior-heat is quenched one's thirst.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Function with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.
Radix Et Caulis Acanthopanacis Senticosi: pungent, micro-hardship, temperature.Return spleen, kidney, heart channel.Function with cure mainly: replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.For deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, insomnia and dreamful sleep.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.
Gecko: salty, flat.Return lung, kidney channel.Function with cure mainly: invigorating the lung and the kidney, improving inspiration by invigorating kidney-QI Dingchuan, supporing yang benefit essence.For lung kidney deficiency, dyspnea due to deficiency tachypnea, chronic cough hemoptysis, sexual impotence, seminal emission.
Bulbus Lilii: sweet, cold.GUIXIN, lung meridian.Function with cure mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN cough caused by dryness, chronic cough hemoptysis, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
Radix Asteris: pungent, bitter, temperature.Return lung meridian.Function with cure mainly: nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.
Radix Platycodonis: bitter, pungent is flat.Return lung meridian.Function with cure mainly: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Herba Cistanches: sweet, salty, temperature.Return kidney, large intestine channel.Function with cure mainly: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For insufficiency of kidney-YANG, blood and essence asthenia, sexual impotence is infertile, soreness of the waist and knees, and muscles and bones is unable, dryness of the intestine constipation.
Fructus Lycii: sweet in the mouth; Property is put down.Return Liver Channel; Kidney channel; Lung meridian.Nourishing the liver, nourishing kidney, lung moistening.For caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; To quench one's thirst taking fluids profusely.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Function with cure mainly: liver and kidney tonifying, arresting collape syndrome by astringents.For dizzy ear toot, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.
Poria: sweet, light is flat.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Pericarpium Citri Reticulatae: bitter, pungent, temperature.Return lung, spleen channel.Function with cure mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Fructus Hippophae: sour, puckery, temperature.Return spleen, stomach, lung, heart channel.Function with cure mainly: strengthening the spleen to promote digestion, eliminating phlegm and stopping cough.Promoting blood circulation to remove blood stasis.For insufficiency of the spleen lack of appetite, abdominal pain due to retention of food, cough with copious phlegm, obstruction of qi in the chest and cardialgia, blood stasis amenorrhea, falls and flutters congestive edema.
The Radix Paeoniae Alba: bitter, sour, is slightly cold.Return liver, spleen channel.Function with cure mainly: nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Fructus Citri Sarcodactylis: pungent, bitter, sour, temperature.Return liver, spleen, stomach, lung meridian.Function with cure mainly: depressed liver-energy dispersing and QI regulating, and stomach and alleviating pain, drying dampness to eliminate phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted, cough with copious phlegm.
Fructus Crataegi: sour, sweet, tepor.Return spleen, stomach, Liver Channel.Function with cure mainly: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, changes turbid blood fat reducing.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, obstruction of qi in the chest and cardialgia, hernia pain, hyperlipemia.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Function with cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Function with cure mainly: invigorate blood circulation, circulation of qi promoting, pain relieving.For the breast side of body, epigastric pain, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Radix Achyranthis Bidentatae: bitter, sweet, sour is flat.Return liver, kidney channel.Function with cure mainly: eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.For amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizzy, toothache, day skin ulcer, spit blood, epistaxis.
Cortex Cinnamomi: pungent, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.Function with cure mainly: mends fiery supporing yang, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.For sexual impotence cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, upward floating of YANG in deficiency condition, dizzy conjunctival congestion, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, and colic of cold type is suffered from abdominal pain, dysmenorrhea amenorrhea.
Radix Aconiti Lateralis Preparata: pungent, sweet is warm greatly; Poisonous.GUIXIN, kidney, spleen channel.Function with cure mainly: recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, dispersing cold for relieving pain.For YANG-depletion collapse, cold extremities faint pulse, deficiency of heart-YANG, obstruction of qi in the chest and cardialgia, deficiency and coldness is vomited and diarrhoea, coldness and pain in the epigastrium, kidney yang deficiency, sexual impotence cold womb, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Herba Schizonepetae: pungent, tepor.Return lung, Liver Channel.Function with cure mainly: induce sweat loose wind, rash, and disappear skin ulcer.For flu, headache, measles, rubella, skin infection from the beginning of.
The Radix Angelicae Dahuricae: pungent, temperature.Return stomach, large intestine, lung meridian.Function with cure mainly: induce sweat cold expelling, wind-expelling pain-stopping, a surname clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction watery nasal discharge, allergic rhinitis, nasal sinusitis, toothache, leukorrhagia, skin infection swells and ache.
Herba Centipedae: acrid in the mouth, warm in nature.Return lung meridian.Function with cure mainly: dispersing wind-cold, clearing the nasal passage, cough-relieving.For headche due to wind-cold, cough with copious phlegm, has a stuffy nose obstructed, nasal sinusitis watery nasal discharge.
Fructus Xanthii: pungent, bitter, temperature; Poisonous.Return lung meridian.Function with cure mainly: dispersing wind and cold, clearing the nasal passage, wind-damp dispelling.For headche due to wind-cold, nasal obstruction watery nasal discharge, allergic rhinitis, nasal sinusitis, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.
"Nei Jing" is thought: " lung opening at nose ", therefore cacorhinia is blamed in lung like working as.But human body is the process of a dynamic equilibrium, be often not limited to internal organs.The traditional Chinese medical science thinks that rhinitis is many because of visceral dysfunction, adds affection of exogenous wind-cold, caused by pathogen invasion and attack nose key.More, be weakened body resistance and evil love first, be second that exopathogen is objective for a long time to this sick touching difficulty.Therefore, vital organs of the human body functional disorder is this, mainly comprise lung, spleen, kidney deficient.Spleen pertaining to the earth is the mother of lung; Kidney belongs to water, Jinsui River alternate.Oral medicine of the present invention with above-mentioned medicament composing prescription, temperature compensation lung qi, invigorating the spleen and benefiting QI, warming and recuperating the kidney-YANG, nourshing blood and promoting blood circulation, cold expelling understand things pain-stopping, based on QI invigorating, conditioning the five internal organs, cold expelling is sensible is auxiliary; Correction uncharms, and reaches the object for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: the present invention, can effective treatment of allergic rhinitis with above-mentioned Chinese prescription.With oral medicine treatment of allergic rhinitis of the present invention, total effective rate is 100%.
Its beneficial effect is further illustrated below in conjunction with clinical observation and model case.
One, clinical observation
1. clinical data: get hospital outpatient catarrhus perennialis patient 170 example, is divided into matched group and each 85 examples of experimental group at random.Matched group man 52 example, female 33 example, 16 ~ 65 years old age, course of disease 1-15; Test group man 48 example, female 37 example, 15 ~ 65 years old age, course of disease 2-15.
2. diagnostic criteria:
2.1 score condition: 1. perennial onset, has sneeze (at every turn continuous more than 3), snivel and nasal mucosa swelling three main clinical manifestation, and number of days of falling ill in a year is accumulative more than 6 months, and in one day, disease time is accumulative more than 0.5 hour; 2. the course of disease at least one year.
2.2 scoring criterias: have clear and definite inhalation (inhalatio) sensitinogen clue, a guy and/or family's anaphylactic disease history, there is typical sings and symptoms stage of attack, each note 1 point, totally 3 points.Allergen skin test positive reaction, has at least a kind of for more than (++) or (++); Specific IgE antibody detects positive or allergen nasal provocation test is positive, and meets with tuerculoderma and medical history, each gets 2 points, totally 4 points.Nasal smear checks that eosinophilic granulocyte is positive and/or nasal mucosa scraping blade mastocyte (basophil) is positive and obtains 1 point.
2.3 standards: score 6 ~ 8 points is diagnosed as catarrhus perennialis, 3 ~ 5 are divided into suspected allergies rhinitis, and 0 ~ 2 point may be non-allergic rhinitis.
3. Therapeutic Method: test group adopts medicine of the present invention, soak by water, every day 1 dose, takes at twice sooner or later; Compound furacilin nasal drops is used to alleviate nasal obstruction symptom if desired.Matched group acute stage oral hismanal, 3mg/ time, external triamcinolone acetonide nasal spray, 1 time/d.
4. efficacy assessment standard: the sum total of scoring according to sings and symptoms before and after treatment, the percentage rate improved is by the curative effect of following formula evaluation perennial allergic rhinitis: total score × 100% before total score/treatment after the front total score-treatment for the treatment of, >=66% is effective, 65 ~ 26% is that effectively≤25% is invalid.
5. therapeutic outcome: statistical result after 1 month, effective 71 examples for the treatment of group, effective 14 examples, invalid 0 example, total effective rate is 100%; Effective 23 examples of matched group, effective 27 examples, invalid 35 examples, total effective rate is 58.9%.
Two, model case
Case 1: Zhang, man, 40 years old.Recurrent exerbation allergic rhinitis more than 5 years, recent sensory symptoms increases the weight of, every morning WA just nasal obstruction, rhinocnesmus, sneeze repeatedly, flow light tears, forehead and the vexed pain of glabella, brains unconsciousness, very painful.Run into cold air obviously to violate, often catch a cold, anemophobia is afraid of cold, spontaneous perspiration.Look into: the hyperemia of bilateral nasal mucosa, slightly edema.Be allergic rhinitis through hospital diagnosis.After taking oral medicine of the present invention 1 course for the treatment of (when having a stuffy nose serious, suitably using compound furacilin nasal drops relief of symptoms in first 3 days), nasal obstruction and rhinocnesmus alleviate, and sneeze number of times obviously reduces.After taking medicine one month continuously, symptomatology disappears.Follow up a case by regular visits to after half a year, allergic rhinitis does not recur.
Case 2: Liu, female, 35 years old.Patient suffers from allergic rhinitis more than 3 years, repeatedly nasal obstruction, rhinorrhea.Must madly sneeze every morning battle array do, after voluntarily medication fail to respond to any medical treatment fruit.Recent nasal mucus is as clear water, and severe nasal blockage, with headache.Time medical, toposcopy: paranasal sinus district is without tenderness, and nose outward appearance is normal, without red and swollen, nothing deformity, nasal mucosa is edema slightly, and secretions is rare clearly.Nasendoscopy: nasal cavity nasal decongestion edema, hypertrophic inferior turbinate, visible watery secretion.Auxiliary examination: hematuria no abnormality seen, x-ray no abnormality seen; Be diagnosed as: allergic rhinitis.After taking oral medicine of the present invention 1 course for the treatment of (when having a stuffy nose serious, suitably using compound furacilin nasal drops relief of symptoms in first 3 days), nasal obstruction, watery nasal discharge alleviate, and sneeze number of times obviously reduces.Take medicine continuously after three courses for the treatment of, symptomatology disappears.Follow up a case by regular visits to after half a year, allergic rhinitis does not recur.
Case 3: Wu, female, 18 years old.Patient catches a cold two months ago, voluntarily pharmacy buy medicine take three days after symptom just disappear, there is again the symptom that nasal obstruction, rhinorrhea, sneeze, intranasal are itched after the week, he think catch a cold completely not good, just then take medicine, two months again and again after nose just start rhinorrhea, nasal obstruction, head all day long and silently swoon.Then remove hospital admission, be diagnosed as: the allergic rhinitis caused because of repeated cold.After taking oral medicine of the present invention 1 course for the treatment of (when having a stuffy nose serious, suitably using compound furacilin nasal drops relief of symptoms in first 3 days), nasal obstruction, watery nasal discharge obviously alleviate.After continuing to take a course for the treatment of, symptomatology disappears.Follow up a case by regular visits to half a year without recurrence.
Detailed description of the invention
Embodiment 1: use when the symptoms such as early stage nasal obstruction, watery nasal discharge, sneeze of taking medicine are heavier
Proportioning: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 12g, Rhizoma Corydalis 10g, Radix Achyranthis Bidentatae 8g, Cortex Cinnamomi 10g, Radix Aconiti Lateralis Preparata 8g, Herba Schizonepetae 15g, Radix Angelicae Dahuricae 10g, Herba Centipedae 15g and Fructus Xanthii 10g.
Preparation and instructions of taking: soak by water, every day, potion, took at twice sooner or later.It within 7 days, is 1 course for the treatment of.When having a stuffy nose serious, suitably can use the nasal formulations alleviating the symptoms such as nasal obstruction, watery nasal discharge, as compound furacilin nasal drops etc.
Embodiment 2: use when the symptoms such as nasal obstruction in mid-term, watery nasal discharge of taking medicine are lighter
Proportioning: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 8g, Radix Achyranthis Bidentatae 6g, Cortex Cinnamomi 5g, Radix Aconiti Lateralis Preparata 3g, Herba Schizonepetae 5g, Radix Angelicae Dahuricae 3g, Herba Centipedae 3g and Fructus Xanthii 3g.
Preparation and instructions of taking: soak by water, every day, potion, took at twice sooner or later.It within 7 days, is 1 course for the treatment of.
Embodiment 3: use during the symptoms such as the later stage of taking medicine almost does not have a stuffy nose, watery nasal discharge
Proportioning: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 8g, Radix Achyranthis Bidentatae 3g, Cortex Cinnamomi 2g, Radix Aconiti Lateralis Preparata 1g, Herba Schizonepetae 1g, Radix Angelicae Dahuricae 1g, Herba Centipedae 1g and Fructus Xanthii 1g.
Preparation and instructions of taking: soak by water, every day, potion, took at twice sooner or later.It within 7 days, is 1 course for the treatment of.
Embodiment 4: use when the symptoms such as early stage nasal obstruction, watery nasal discharge, sneeze of taking medicine are heavier
Proportioning: Radix Codonopsis 18g, Radix Astragali 18g, Radix Rehmanniae Preparata 12g, Rhizoma Polygonati 15g, Fructus Schisandrae Chinensis 8g, Radix Et Caulis Acanthopanacis Senticosi 10g, Rhizoma Dioscoreae 12g, Gecko 8g, Bulbus Lilii 8g, Radix Asteris 8g, Radix Platycodonis 8g, Herba Cistanches 12g, Fructus Lycii 12g, Fructus Corni 10g, Poria 10g, Rhizoma Atractylodis Macrocephalae 15g, Pericarpium Citri Reticulatae 10g, Fructus Hippophae 8g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 8g, Fructus Crataegi 10g, Radix Glycyrrhizae 8g, Radix Angelicae Sinensis 15g, Rhizoma Corydalis 12g, Radix Achyranthis Bidentatae 8g, Cortex Cinnamomi 10g, Radix Aconiti Lateralis Preparata 8g, Herba Schizonepetae 15g, Radix Angelicae Dahuricae 10g, Herba Centipedae 15g and Fructus Xanthii 10g.
Preparation and instructions of taking: with embodiment 1.
Embodiment 5: use during the symptoms such as the later stage of taking medicine almost does not have a stuffy nose, watery nasal discharge
Proportioning: Radix Codonopsis 12g, Radix Astragali 12g, Radix Rehmanniae Preparata 8g, Rhizoma Polygonati 10g, Fructus Schisandrae Chinensis 5g, Radix Et Caulis Acanthopanacis Senticosi 5g, Rhizoma Dioscoreae 8g, Gecko 3g, Bulbus Lilii 3g, Radix Asteris 3g, Radix Platycodonis 3g, Herba Cistanches 10g, Fructus Lycii 8g, Fructus Corni 5g, Poria 5g, Rhizoma Atractylodis Macrocephalae 10g, Pericarpium Citri Reticulatae 5g, Fructus Hippophae 3g, Radix Paeoniae Alba 3g, Fructus Citri Sarcodactylis 3g, Fructus Crataegi 5g, Radix Glycyrrhizae 3g, Radix Angelicae Sinensis 5g, Rhizoma Corydalis 5g, Radix Achyranthis Bidentatae 3g, Cortex Cinnamomi 2g, Radix Aconiti Lateralis Preparata 1g, Herba Schizonepetae 1g, Radix Angelicae Dahuricae 1g, Herba Centipedae 1g and Fructus Xanthii 1g.
Preparation and instructions of taking: with embodiment 3.

Claims (4)

1. the oral medicine of a treatment of allergic rhinitis, it is characterized in that, be made up of the crude drug of following weight: Radix Codonopsis 12-18g, Radix Astragali 12-18g, Radix Rehmanniae Preparata 8-12g, Rhizoma Polygonati 10-15g, Fructus Schisandrae Chinensis 5-8g, Radix Et Caulis Acanthopanacis Senticosi 5-10g, Rhizoma Dioscoreae 8-12g, Gecko 3-8g, Bulbus Lilii 3-8g, Radix Asteris 3-8g, Radix Platycodonis 3-8g, Herba Cistanches 10-15g, Fructus Lycii 8-12g, Fructus Corni 5-10g, Poria 5-10g, Rhizoma Atractylodis Macrocephalae 10-15g, Pericarpium Citri Reticulatae 5-10g, Fructus Hippophae 3-8g, Radix Paeoniae Alba 3-8g, Fructus Citri Sarcodactylis 3-8g, Fructus Crataegi 5-10g, Radix Glycyrrhizae 3-8g, Radix Angelicae Sinensis 5-15g, Rhizoma Corydalis 5-12g, Radix Achyranthis Bidentatae 3-10g, Cortex Cinnamomi 1-12g, Radix Aconiti Lateralis Preparata 1-10g, Herba Schizonepetae 1-18g, Radix Angelicae Dahuricae 1-10g, Herba Centipedae 1-15g and Fructus Xanthii 1-10g.
2. the oral medicine of a kind for the treatment of of allergic rhinitis as claimed in claim 1, it is characterized in that, be made up of the crude drug of following weight: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 12g, Rhizoma Corydalis 10g, Radix Achyranthis Bidentatae 8g, Cortex Cinnamomi 10g, Radix Aconiti Lateralis Preparata 8g, Herba Schizonepetae 15g, Radix Angelicae Dahuricae 10g, Herba Centipedae 15g and Fructus Xanthii 10g.
3. the oral medicine of a kind for the treatment of of allergic rhinitis as claimed in claim 1, it is characterized in that, be made up of the crude drug of following weight: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 8g, Radix Achyranthis Bidentatae 6g, Cortex Cinnamomi 5g, Radix Aconiti Lateralis Preparata 3g, Herba Schizonepetae 5g, Radix Angelicae Dahuricae 3g, Herba Centipedae 3g and Fructus Xanthii 3g.
4. the oral medicine of a kind for the treatment of of allergic rhinitis as claimed in claim 1, it is characterized in that, be made up of the crude drug of following weight: Radix Codonopsis 15g, Radix Astragali 15g, Radix Rehmanniae Preparata 10g, Rhizoma Polygonati 12g, Fructus Schisandrae Chinensis 6g, Radix Et Caulis Acanthopanacis Senticosi 8g, Rhizoma Dioscoreae 10g, Gecko 5g, Bulbus Lilii 5g, Radix Asteris 5g, Radix Platycodonis 5g, Herba Cistanches 12g, Fructus Lycii 10g, Fructus Corni 8g, Poria 8g, Rhizoma Atractylodis Macrocephalae 12g, Pericarpium Citri Reticulatae 8g, Fructus Hippophae 5g, Radix Paeoniae Alba 8g, Fructus Citri Sarcodactylis 5g, Fructus Crataegi 8g, Radix Glycyrrhizae 5g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 8g, Radix Achyranthis Bidentatae 3g, Cortex Cinnamomi 2g, Radix Aconiti Lateralis Preparata 1g, Herba Schizonepetae 1g, Radix Angelicae Dahuricae 1g, Herba Centipedae 1g and Fructus Xanthii 1g.
CN201510172407.7A 2015-04-13 2015-04-13 Oral medicine for treating allergic rhinitis Pending CN104721553A (en)

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CN105231305A (en) * 2015-10-22 2016-01-13 全椒贡菊园茶厂 Method for making medicated stewed chicken treating allergic rhinitis
CN106138745A (en) * 2016-08-31 2016-11-23 张明 A kind of for Chinese medicine preparation treating rhinitis and preparation method thereof
CN108187017A (en) * 2018-03-14 2018-06-22 长春人民药业集团有限公司 The Chinese medicine composition for treating Lungs of Children cough is preparing the application in treating rhinitis drug

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CN105231305A (en) * 2015-10-22 2016-01-13 全椒贡菊园茶厂 Method for making medicated stewed chicken treating allergic rhinitis
CN106138745A (en) * 2016-08-31 2016-11-23 张明 A kind of for Chinese medicine preparation treating rhinitis and preparation method thereof
CN108187017A (en) * 2018-03-14 2018-06-22 长春人民药业集团有限公司 The Chinese medicine composition for treating Lungs of Children cough is preparing the application in treating rhinitis drug

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Application publication date: 20150624