CN103957727B - 用于体重减轻饮食之后的体重稳定的植物蜕皮激素 - Google Patents

用于体重减轻饮食之后的体重稳定的植物蜕皮激素 Download PDF

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Publication number
CN103957727B
CN103957727B CN201280055214.8A CN201280055214A CN103957727B CN 103957727 B CN103957727 B CN 103957727B CN 201280055214 A CN201280055214 A CN 201280055214A CN 103957727 B CN103957727 B CN 103957727B
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phytoecdysone
extract
diet
weight
quinoa
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Chinese (zh)
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CN103957727A (zh
Inventor
勒内·拉丰
卡里纳·克莱门特
萨尔瓦·里兹卡拉
斯坦尼斯拉斯·韦耶
安妮-索菲·富科
瓦利·迪奥
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Co Is Ortiz
Universite Pierre et Marie Curie
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Universite Pierre et Marie Curie
Institut Biophytis SAS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/55—Liquid-liquid separation; Phase separation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN201280055214.8A 2011-11-10 2012-11-12 用于体重减轻饮食之后的体重稳定的植物蜕皮激素 Active CN103957727B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1160280A FR2982489B1 (fr) 2011-11-10 2011-11-10 Phytoecdysones pour leur utilisation dans la stabilisation du poids apres un regime amaigrissant
FR1160280 2011-11-10
PCT/FR2012/052600 WO2013068704A1 (fr) 2011-11-10 2012-11-12 Phytoecdysones pour leur utilisation dans la stabilisation du poids après un régime amaigrissant

Publications (2)

Publication Number Publication Date
CN103957727A CN103957727A (zh) 2014-07-30
CN103957727B true CN103957727B (zh) 2016-09-14

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CN201280055214.8A Active CN103957727B (zh) 2011-11-10 2012-11-12 用于体重减轻饮食之后的体重稳定的植物蜕皮激素

Country Status (12)

Country Link
US (3) US20140309203A1 (enExample)
EP (1) EP2775859B1 (enExample)
JP (2) JP6346094B2 (enExample)
CN (1) CN103957727B (enExample)
DK (1) DK2775859T3 (enExample)
ES (1) ES2618023T3 (enExample)
FR (1) FR2982489B1 (enExample)
HR (1) HRP20170260T1 (enExample)
HU (1) HUE031953T2 (enExample)
PL (1) PL2775859T3 (enExample)
PT (1) PT2775859T (enExample)
WO (1) WO2013068704A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3021318B1 (fr) * 2014-05-20 2017-04-28 Inst Biophytis Produits derives de la 20-hydroxyecdysone et leur utilisation dans la preparation de medicaments
FR3078252B1 (fr) * 2018-02-28 2020-08-14 Biophytis Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation
WO2019235011A1 (ja) 2018-06-06 2019-12-12 株式会社島津製作所 分析方法および分析装置
WO2021090177A1 (en) * 2019-11-04 2021-05-14 Sun Pharmaceutical Industries Limited Compounds for treatment of dengue infection
FR3158880A1 (fr) 2024-02-01 2025-08-08 Biophytis Phytoecdysones et/ou dérivés de 20-hydroxyecdysone en combinaison avec un agoniste de GLP-1 pour leur utilisation dans le traitement de l’obésité et du surpoids

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101735299A (zh) * 2010-01-05 2010-06-16 云南植物药业有限公司 一种从露水草中提取蜕皮激素的方法及其蜕皮激素
CN102014626A (zh) * 2008-03-14 2011-04-13 英特瑞克斯顿股份有限公司 甾族配体及其在基因开关调控中的应用
CN102231986A (zh) * 2007-11-30 2011-11-02 比奥菲蒂斯研究所简单股份有限公司 植物蜕皮激素在制备对代谢综合征有效的组合物中的用途

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Publication number Priority date Publication date Assignee Title
US5688772A (en) * 1994-08-01 1997-11-18 University Of Saskatchewan Quinoa saponin compositions and methods of use
JPH11209279A (ja) * 1998-01-05 1999-08-03 Natural Ltd As 体重減少および肥満処置の方法
US6355249B2 (en) * 1998-04-17 2002-03-12 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Canada Process for recovery and purification of saponins and sapogenins from quinoa (Chenopodium quinoa)
GB2420066A (en) * 2004-11-23 2006-05-17 Nor Feed As Feed additive derived from plant material originating from quinoa (Chenopodium quinoa)
US20070196517A1 (en) * 2005-07-13 2007-08-23 Dictuc S.A. Modified Saponin Molluscicide
CN101011436A (zh) * 2007-01-20 2007-08-08 苏州大学 牛膝总甾酮的医药用途
JP2010202569A (ja) * 2009-03-03 2010-09-16 Showa Women's Univ 抗アレルギー及び抗炎症用組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102231986A (zh) * 2007-11-30 2011-11-02 比奥菲蒂斯研究所简单股份有限公司 植物蜕皮激素在制备对代谢综合征有效的组合物中的用途
CN102014626A (zh) * 2008-03-14 2011-04-13 英特瑞克斯顿股份有限公司 甾族配体及其在基因开关调控中的应用
CN101735299A (zh) * 2010-01-05 2010-06-16 云南植物药业有限公司 一种从露水草中提取蜕皮激素的方法及其蜕皮激素

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ecdysteroids of Quinoa Seeds (Chenopodium quinoa Willd.);Nanqun Zhu等;《J. Agric. Food Chem.》;20011231;第49卷;第2576-2578页 *
植物蜕皮激素的研究进展;胥秀英等;《生物学杂志》;20050430;第22卷(第2期);第12-14和55页 *

Also Published As

Publication number Publication date
PL2775859T3 (pl) 2017-07-31
US20200100534A1 (en) 2020-04-02
PT2775859T (pt) 2017-03-10
EP2775859B1 (fr) 2017-01-18
HRP20170260T1 (hr) 2017-06-16
US20170071955A1 (en) 2017-03-16
JP6346094B2 (ja) 2018-06-20
CN103957727A (zh) 2014-07-30
FR2982489A1 (fr) 2013-05-17
JP2014533256A (ja) 2014-12-11
HUE031953T2 (en) 2017-08-28
JP2018109023A (ja) 2018-07-12
WO2013068704A1 (fr) 2013-05-16
US20140309203A1 (en) 2014-10-16
JP6462918B2 (ja) 2019-01-30
ES2618023T3 (es) 2017-06-20
DK2775859T3 (en) 2017-03-06
EP2775859A1 (fr) 2014-09-17
FR2982489B1 (fr) 2013-12-27

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Address after: France

Patentee after: The company is Ortiz

Patentee after: Univ Paris Curie

Address before: Paris, France

Patentee before: Inst Biophytis SAS

Patentee before: Univ Paris Curie