CN103936881B - 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 - Google Patents
一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 Download PDFInfo
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- CN103936881B CN103936881B CN201310142747.6A CN201310142747A CN103936881B CN 103936881 B CN103936881 B CN 103936881B CN 201310142747 A CN201310142747 A CN 201310142747A CN 103936881 B CN103936881 B CN 103936881B
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- Prior art keywords
- sodium alginate
- sodium
- bone
- product
- carboxymethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (3)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711407772.7A CN107875167A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
CN201711405606.3A CN107929310A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
CN201310142747.6A CN103936881B (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310142747.6A CN103936881B (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711405606.3A Division CN107929310A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
CN201711407772.7A Division CN107875167A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103936881A CN103936881A (zh) | 2014-07-23 |
CN103936881B true CN103936881B (zh) | 2018-06-19 |
Family
ID=51184782
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711407772.7A Pending CN107875167A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
CN201711405606.3A Pending CN107929310A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
CN201310142747.6A Expired - Fee Related CN103936881B (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201711407772.7A Pending CN107875167A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
CN201711405606.3A Pending CN107929310A (zh) | 2013-04-24 | 2013-04-24 | 一种促进骨形成蛋白表达加速骨折愈合的药物的制备方法 |
Country Status (1)
Country | Link |
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CN (3) | CN107875167A (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1943797A (zh) * | 2006-10-23 | 2007-04-11 | 厦门大学 | 海藻酸钠-羧甲基纤维素复合骨骼粘合剂及其制备方法 |
CN101787267A (zh) * | 2010-03-17 | 2010-07-28 | 西南石油大学 | 油气田钻井液用双改性淀粉降滤失剂及其制备方法 |
CN103041442A (zh) * | 2013-01-23 | 2013-04-17 | 厦门大学 | 一种基于海藻酸钠的骨骼粘合剂及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008127290A2 (en) * | 2006-10-12 | 2008-10-23 | The Johns Hopkins University | Alginate and alginate lyase compositions and methods of use |
CN102349929B (zh) * | 2011-09-28 | 2012-09-05 | 郭宏昌 | 一种治疗和预防骨折的药物 |
CN103830266A (zh) * | 2013-04-24 | 2014-06-04 | 杨亚勤 | 部分氧化海藻酸钠羧甲基化衍生物的制备方法和应用 |
-
2013
- 2013-04-24 CN CN201711407772.7A patent/CN107875167A/zh active Pending
- 2013-04-24 CN CN201711405606.3A patent/CN107929310A/zh active Pending
- 2013-04-24 CN CN201310142747.6A patent/CN103936881B/zh not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1943797A (zh) * | 2006-10-23 | 2007-04-11 | 厦门大学 | 海藻酸钠-羧甲基纤维素复合骨骼粘合剂及其制备方法 |
CN101787267A (zh) * | 2010-03-17 | 2010-07-28 | 西南石油大学 | 油气田钻井液用双改性淀粉降滤失剂及其制备方法 |
CN103041442A (zh) * | 2013-01-23 | 2013-04-17 | 厦门大学 | 一种基于海藻酸钠的骨骼粘合剂及其制备方法 |
Non-Patent Citations (1)
Title |
---|
羧化改性海藻酸钠沉淀吸附铜离子的研究;钟超凡等;《湘潭大学自然科学学报》;20051231;第27卷(第4期);第81-83页及第89页 * |
Also Published As
Publication number | Publication date |
---|---|
CN107929310A (zh) | 2018-04-20 |
CN103936881A (zh) | 2014-07-23 |
CN107875167A (zh) | 2018-04-06 |
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Effective date of registration: 20170615 Address after: Mengzhou City, Henan Province, 454750 Large Office North Village Wang Zhuang instrument No. 61 North Street Applicant after: Wang Panfeng Address before: 453003 Xinxiang Medical University, Henan, Xinxiang Applicant before: Xinxiang Medical College |
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TA01 | Transfer of patent application right |
Effective date of registration: 20180517 Address after: 510000 2417, 2 Building 8, Fenghuang three road, Guangzhou new knowledge city, Guangzhou, Guangdong. Applicant after: Guangzhou OSI Medical Technology Co., Ltd. Address before: 454750 Wang Zhuang North Street 61, North Kai Ye Village, Da Ding office, Mengzhou, Henan. Applicant before: Wang Panfeng |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180619 Termination date: 20200424 |
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CF01 | Termination of patent right due to non-payment of annual fee |