CN103931953A - Feed for preventing and controlling edema disease of swine, Chinese medicinal composition and preparation method - Google Patents
Feed for preventing and controlling edema disease of swine, Chinese medicinal composition and preparation method Download PDFInfo
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Abstract
The invention discloses a feed for preventing and controlling edema disease of swine, a Chinese medicinal composition and a preparation method. The feed comprises Chinese medicinal additives, montmorillonite, beer yeast, a trace element chelating agent, corn, hay and bacillus, wherein the Chinese medicinal additives comprise medicated leaven, rice-grain sprout, amomum fruit, large-head atractylodes rhizome, Chinese fever vine, baikal skullcap root, honeysuckle flower, cynanchum wilfordii, Chinese asafetida, ruddle, bamboo shavings, uncaria, tall gastrodia tuber, rhizoma arisaematis, borneol, dogbane leaf, common selfheal fruit-spike, akebia stem, umbellate pore fungus, oriental waterplantain rhizome, liquoric root, common andrographis herb, cyrtomium rhizome, paris rhizome, Indian trum etflower seed, plumed thistle root, beautiful sweetgum fruit and prickly knotweed. The feed provided by the invention contains the Chinese medicinal additives, has the functions of strengthening the spleen and stomach and clearing away heat and toxic materials, has the advantages of remarkable clinical effect, no toxic or side effect, low price, is easy and convenient to prepare, is capable of improving the body immunity and disease resistance of sick swine in the prevention and control of edema disease of swine, and has a certain health care function on consumers eating the type of pork.
Description
Technical field
The present invention relates to technical field of animal, particularly a kind of for preventing and treating feed, Chinese medicine composition and the preparation method of bowel oedema disease.
Background technology
Bowel oedema disease claims again colitoxemia, edema disease, gastric edema.Be the disease of a kind of acute, lethal of piggy, it is characterized by coat of the stomach and oedema occurs at some other position.
This disease mainly betides ablactation piglet, and little of age a few days, there is generation at greatly to 4 monthly age.The piglet that growth is fast, body condition is healthy and strong is the most common, and modest piglet occurs less.The sow that carries disease germs is propagated to piglet, is region popular, is often limited to the piglet of some pig farm and some nest.Feed method for breeding changes, and feed is single, climate change, and the water after contaminated, environment, apparatus etc. all can cause this sick Probability to increase and symptom increases the weight of.This disease all can occur throughout the year, but is more common in spring and autumn., generally there is not this disease in the piglet that crosses yellow dysentery as nascent.
Clinical symptoms
Sick pig sudden onset, spirit is depressed, poor appetite, mouthful stream foam, body temperature, without significant change, has laxativeness, rear constipation for 1-2 days before disease.Heartbeat quickly, is breathed just fast and shallow, slow and dark afterwards.The sleeping ground of happiness, muscular tremor, twitch frequently, major beat swimming shape, and groan, haunch while standing, shakes.Forelimb is as benumbed, astasia, and rear acroparalysis, can not stand.Weakness of limbs when walking, incoordination, gait is waved shakiness, blindly advances or makes circular motion.Oedema is this sick characteristic symptom, is common in the subcutaneous of face, eyelid, conjunctiva, gums, neck, belly.The sick pig having does not have the variation of oedema.The only a few hours that the course of disease is short, are generally 1-2 days, also have and reach more than 7 days.Case fatality rate approximately 90%.
Be mainly sudden onset, body temperature is not high, quadruped locomotion obstacle, and rear quarters is unable, waves and incoordination; The sick pig having does circular motion or blindly disorderly punching, suddenly violent body wash-ahead; Various stimulations or while catching, the scream of touching, calls hoarsely, falls down to the ground, four limbs are touched, the shape of seemingly swimming; The common face of sick pig, palpebral edema, severe one is extended down to face, neck, and it is fat that head becomes.
Doctor trained in Western medicine is prevented and treated bowel oedema disease and at present this disease be there is no to special effective therapy, prevents this sick key to be to improve feeding and management, and feed nutrition is wanted comprehensively, and protein can not be too high.Medicine treatment early stage results is good, and the later stage is generally invalid.
Chinese traditional treatment bowel oedema disease has advantageous clinical efficacy.The traditional Chinese medical science is carried out dialectical opinion and is controlled on the basis of Overall View, for the disease instant effect of same class card, and short treating period, clinical effectiveness is obvious.And, pure natural, have no side effect, drug residue free, medicinal material cost price is cheap, simple for production, can improve immunity of organisms and the resistance against diseases of ill pig, also can play certain health-care effect to the consumer of edible this type of pork simultaneously.
Summary of the invention
Technical problem to be solved by this invention is to be to provide a kind of feed that comprises the Chinese medicine composition for preventing and treating bowel oedema disease, the feed that employing contains this Chinese medicine composition can overcome the defect of prior art Chinese and Western medicine and Chinese medicine, treatment to the pig that suffers from bowel oedema disease has strengthening the spleen and stomach, clearing heat and detoxicating function, and instant effect, short treating period, curative effect really, be difficult for developing immunity to drugs, be difficult for the advantage that recurrence, few side effects, livestock products drug residue are low, inexpensive, be conducive to person poultry safety.
In order to realize foregoing invention object, the invention provides a kind of for preventing and treating the feed of bowel oedema disease, comprise that Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, described Chinese medicine additive comprise that Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.
In described Chinese medicine additive, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, the mountain on the other way round 14-26 weight portion that disappears, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, 18-34 weight portion and shoulder plate and return 9-27 weight portion plays both sides of the street.
In described feed, the weight portion of each component is: described Chinese medicine additive 12-16 weight portion, trace element chelated dose of 2-6 weight portion, sugared brewer's yeast 0.2-0.7 weight portion, corn 46-67 weight portion, hay 41-65 weight portion, bacillus 0.4-0.9 weight portion, montmorillonite 3-5 weight portion.
Described bacillus comprises one or both mixing in bacillus subtilis and bacillus licheniformis.
Described trace element chelated dose comprises hemoglobin, cytochrome oxidase and Cobastab
12.
In described Chinese medicine additive, the weight portion of each bulk drug also can be: Divine Comedy 19-31 weight portion, rice bud 13-22 weight portion, fructus amomi 21-30 weight portion, bighead atractylodes rhizome 25-32 weight portion, fevervine 13-21 weight portion, root of large-flowered skullcap 22-33 weight portion, honeysuckle 30-38 weight portion, the mountain on the other way round 16-24 weight portion that disappears, asafoetide 12-22 weight portion, raddle 16-25 weight portion, caulis bambusae in taenian 18-27 weight portion, yncaria stem with hooks 9-18 weight portion, rhizoma Gastrodiae 23-33 weight portion, rhizoma arisaematis 3-7 weight portion, borneol 19-26 weight portion, bluish dogbane 22-33 weight portion, selfheal 11-20 weight portion, akebi 30-37 weight portion, umbellate pore furgus 20-28 weight portion, rhizoma alismatis 17-26 weight portion, Radix Glycyrrhizae 14-21 weight portion, Herba Andrographitis 23-32 weight portion, rhizome of cyrtomium 5-11 weight portion, Paris polyphylla 10-18 weight portion, Oroxylum indicum 14-25 weight portion, Root of Loping Thistle 27-37 weight portion, 20-31 weight portion and shoulder plate 11-24 weight portion plays both sides of the street.
In described Chinese medicine additive, the weight portion of each bulk drug can be again: Divine Comedy 21-28 weight portion, rice bud 14-21 weight portion, fructus amomi 23-28 weight portion, bighead atractylodes rhizome 26-31 weight portion, fevervine 15-20 weight portion, root of large-flowered skullcap 24-30 weight portion, honeysuckle 31-37 weight portion, the mountain on the other way round 17-22 weight portion that disappears, asafoetide 14-20 weight portion, raddle 18-23 weight portion, caulis bambusae in taenian 19-25 weight portion, yncaria stem with hooks 10-17 weight portion, rhizoma Gastrodiae 25-31 weight portion, rhizoma arisaematis 3-6 weight portion, borneol 19-24 weight portion, bluish dogbane 22-29 weight portion, selfheal 11-18 weight portion, akebi 32-37 weight portion, umbellate pore furgus 21-27 weight portion, rhizoma alismatis 17-23 weight portion, Radix Glycyrrhizae 14-18 weight portion, Herba Andrographitis 25-31 weight portion, rhizome of cyrtomium 5-9 weight portion, Paris polyphylla 10-16 weight portion, Oroxylum indicum 16-24 weight portion, Root of Loping Thistle 28-36 weight portion, 21-28 weight portion and shoulder plate and return 13-21 weight portion plays both sides of the street.
It is a kind of for preventing and treating the preparation method of feed of bowel oedema disease that the present invention also provides, and comprises the following steps:
The first step, corn, hay are dropped in mixer and mixed in proportion, adding the content of moisture in water, control mixture is 59%-82%, stir, after add in proportion brewer's yeast, bacillus, mixed material is added in horizental silo, by the material compacting mixing, cover tightly, cause the inner anaerobic environment of material, at the temperature bottom fermentation 35-40 days of 19 DEG C-30 DEG C, rear acquisition fermented product, is dried fermentation material, obtain the solid fermentation product of moisture below 7%, be ground into powder;
Second step, described montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μ m;
The 3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, the ethanol that to add subsequently with respect to the determining alcohol of 3 times of its quality be 73-86%, add hot reflux 2 hours, filter, filtered fluid is refrigerated at-1.0 DEG C and spend the night, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
The 4th step, the montmorillonite ultra-micro powder that the fermented product powder that the first step is obtained, second step obtain, the Chinese medicine additive powder that the 3rd step obtains and trace element chelated dose of mixing in proportion, obtain described feed.
It is a kind of for preventing and treating the Chinese medicine composition of bowel oedema disease that the present invention also provides, Chinese medicine composition comprises the bulk drug of following ratio of weight and number: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, the mountain on the other way round 14-26 weight portion that disappears, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, 18-34 weight portion and shoulder plate and return 9-27 weight portion plays both sides of the street.
The preparation method of described Chinese traditional medicine composition composition powders comprises:
Step 1, all bulk drugs are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add the water doubly measured with respect to its quality 5-7, boil 2-4 hour, steam pressure is that 0.6-1Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to the water doubly measured with respect to its quality 5-7, boils 2-4 hour, steam pressure is that 0.6Mpa-1Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
The beneficial effect that technical scheme provided by the invention is brought is: feed provided by the invention contains Chinese medicine additive, there is strengthening the spleen and stomach, clearing heat and detoxicating function, there is instant effect in anti-treatment bowel oedema disease, short treating period, clinical effectiveness obviously, have no side effect, cheap, simple for production and can improve the immunity of organisms of ill pig and the advantage of resistance against diseases, the while also can be played certain health-care effect to the consumer who eats this type of pork.
Detailed description of the invention
Chinese veterinarian thinks the operation of water liquid depends on the promotion of gas, and the liter that depends on temper is transferred, and the Xuan Jiangtong of lung qi adjusts, the promotion of the motive, kidney qi evaporate folding.These functions are normal, and effect is certainly shown disrespect in three warmers performance, and functioning of bladder passes unimpeded, and normal urination can maintain the metabolism of normal water liquid.Otherwise, if because of the damp and hot heresy of catching cold, the wet dipping of water, sore contamination, improper diet and overtiredness, weakness due to chronic disease etc. cause above-mentioned visceral dysfunction, and three warmers are certainly shown disrespect on mistake department, and functioning of bladder is unfavorable, and water retention in body, spreads unchecked skin, can send out as oedema.
Therefore, the present invention treats bowel oedema disease, with strengthening the spleen and stomach, clearing heat and detoxicating is primary treatment principle, selects prescription: Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.
The invention provides a kind of for preventing and treating the feed of bowel oedema disease, comprise that Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, described Chinese medicine additive comprise that Divine Comedy, rice bud, fructus amomi, the bighead atractylodes rhizome, fevervine, the root of large-flowered skullcap, honeysuckle, mountain on the other way round disappear, asafoetide, raddle, caulis bambusae in taenian, yncaria stem with hooks, rhizoma Gastrodiae, rhizoma arisaematis, borneol, bluish dogbane, selfheal, akebi, umbellate pore furgus, rhizoma alismatis, Radix Glycyrrhizae, Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum, Root of Loping Thistle, play both sides of the street and shoulder plate and return.
In Chinese medicine additive, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, the mountain on the other way round 14-26 weight portion that disappears, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, 18-34 weight portion and shoulder plate and return 9-27 weight portion plays both sides of the street.
Wherein, Divine Comedy pungent with row loose help digestion, sweet temperature spleen benefiting and stimulating the appetite and middle antidiarrheal, can bring down a fever again; Rice bud is aid digestion and the gas that do not injure one's stomach, with fructus amomi, the bighead atractylodes rhizome, Radix Glycyrrhizae compatibility with using; Fevervine food digesting stomach fortifying, preventing phlegm from forming and stopping coughing, clearing heat and detoxicating, pain relieving, with the root of large-flowered skullcap, the same use of honeysuckle compatibility; Mountain on the other way round disappear stomach invigorating, regulating qi-flowing for relieving pain, with fructus amomi compatibility with using; Asafoetide is returned liver taste warp, is equal to use with the bighead atractylodes rhizome; Raddle is calming the liver, contrary, cooling blood and hemostasis falls in important city, with caulis bambusae in taenian, the same use of Root of Loping Thistle compatibility; Bluish dogbane can suppressing liver-YANG, heat-clearing, diuresis, with yncaria stem with hooks, selfheal, akebi, umbellate pore furgus, rhizoma alismatis compatibility with using; Rhizoma Gastrodiae can relieving convulsion and spasm, suppressing liver-YANG, with yncaria stem with hooks, the bighead atractylodes rhizome, rhizoma arisaematis compatibility with using; Borneol have one's ideas straightened out inducing resuscitation, clearing away heat to and alleviating pain; Herba Andrographitis, rhizome of cyrtomium, Paris polyphylla, Oroxylum indicum compatibility can be clearing heat and detoxicating, cooling blood and hemostasis, detumescence; The dispelling, collateral-activating that plays both sides of the street, Li Shui stimulates the menstrual flow; Shouldering plate returns clearing heat and detoxicating; Inducing diuresis and reducing edema; Radix Glycyrrhizae coordinating the drug actions of a prescription.
The pharmacology of described each bulk drug is as follows:
Divine Comedy: nature and flavor hardship, temperature.Return spleen, stomach, large intestine channel.Can reinforcing spleen to promote digestion, regulating QI to expel dampness, induces sweat.The food feeling of stuffiness in chest that cures the wound, stomachache is vomited and diarrhoea, dysentery, cold headache, children's hinder hungry lose full.
Rice bud: nature and flavor are sweet is flat.Return spleen, stomach warp, Liver Channel.Have promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back effect of newborn dissipate-swelling.Cure mainly dyspepsia and do not disappear, abdominal distention, insufficiency of the spleen food is few, and newborn sweat smoulders, swollen breasts, women's ablactation.
Fructus amomi: taste is pungent, warm in nature.Return the spleen channel, stomach warp, kidney channel.Function dampness elimination appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, and vomiting is had loose bowels, pernicious vomiting, fetal irritability.
The bighead atractylodes rhizome: taste is sweet, bitter, warm in nature.Return spleen, stomach warp.There is tonifying spleen profit gas, eliminating dampness Li Shui, strengthening exterior and reducing sweat, effect that fortune spleen is moisturized, cures mainly ruffian due to the dysfunction of the spleen in transport, QI failing to transform into body fluid and has one's mind filled with and rush down, phlegm and retained fluid oedema; The vexed lazy speech of the deficiency of qi in middle-jiao, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, abnormal sweating spontaneous perspiration.
Fevervine: property is flat, sweet, the micro-hardship of taste.Expelling wind and activating blood flow, analgesic antidotal, promoting digestion, dehumidifying detumescence.Treatment of rheumatalgia pain, diarrhoea dysentery, dirty abdomen pain, deficiency of vital energy edema, dizzy food is few, hepatosplenomegaly, scrofula, acute appendicitis, nameless sores or boils, traumatic injury.
The root of large-flowered skullcap: property hardship, cold.Return lung, courage, spleen, large intestine, small intestinl channel.Can heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive, hypotensive.For damp-warm syndrome, the heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, rushes down dysentery, jaundice, and cough with lung heat, high hot polydipsia, blood-head is told nosebleed, carbuncle sore tumefacting virus, fetal irritability.
Honeysuckle: cold in nature, taste is sweet.Return lung, the heart, stomach warp.There is clearing heat and detoxicating, anti-inflammatory, qi-restoratives and treat effect of wind, cure mainly disease under turgor, warm disease heating, the diseases such as hot malicious large carbuncle and tumour.The illnesss such as it is dizzy for giddy, dry is done yearningly, hidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, mumps, suppurative tonsillitis all have certain curative effect.
Mountain on the other way round disappears: bitter but sweet flavor is puckery, and slightly warm in nature is nontoxic.Return liver, kidney two warps.Nourishing liver and kidney, strengthening body, nourishes blood and enriches blood, black of crow palpus, and convergence vital essence, regenerating tissue to heal wond, relaxes bowel.Control prolonged illness weakness, chronic wandering arthritis, soreness and weakness of waist and knees, anaemia, enterorrhagia, poliosis, neurasthenia, deficiency of Yin chronic malaria, ulcer does not close up for a long time, old man's constipation.
Asafoetide: bitter, pungent, warm in nature.Return kidney, stomach warp.Have disappear long-pending, loose ruffian, effect of desinsection, stagnant for meat, hemostasis abdominal mass, mass in abdomen, the cards such as abdominal pain due to enterositosis.
Raddle: bitter sweet, flat.Return liver, stomach, heart born of the same parents warp.Ping Gan town is contrary, cooling blood and hemostasis.Control gas vomit contrary, dysphagia and regurgitation, asthma, frightened epilepsy, spits blood, nosebleed epistaxis, intestines wind, hemorrhoid complicated by anal fistula, under uterine bleeding band.
Caulis bambusae in taenian: cold nature, taste is sweet.Attach to the lung and stomach meridians.Function clearing heat and eliminating phlegm, relieves restlessness and prevents vomiting.Hold phlegm, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, apoplexy phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pernicious vomiting, fetal irritability under the arm for phlegm-heat cough, courage fire.
Yncaria stem with hooks: sweet, hardship, is slightly cold.Return Liver Channel, the heart channel of Hang-Shaoyin.The flat liver of function heat-clearing, relieving convulsion and spasm.Cure mainly child convulsion, the morbid night crying of babies, heat is contained moving wind, eclampsia, dizziness due to hyperactivity of liver-YANG, irascibility distending pain in the head.
Rhizoma Gastrodiae: Gan Ping.Return Liver Channel.Embellish but not dry, master enters Liver Channel, is longer than suppressing hyperactive liver for calming endogenous wind, and the disease of all liver wind agitations, vertigo, no matter actual situation is key medicine.
Rhizoma arisaematis: bitter, pungent, temperature.Return lung, liver, the spleen channel.Eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.Cough for stupid productive cough, wind disease is dizzy, and apoplexy phlegm is stopped up, facial paralysis, hemiplegia, epilepsy, infantile convulsion, lockjaw; Swollen for carbuncle outward, snake bite and insect sting.
Borneol: arduous, cool.The thoughts of returning home, lung channel.Logical all keys, loose stagnated fire, goes screen improving eyesight, swelling and pain relieving.Control middle air port and keep silent, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle is swollen, hemorrhoid, order is screen film also, enterobiasis.
Bluish dogbane: sweetness and bitterness, cool.Control heart disease, hypertension, neurasthenia, hepatitis abdominal distension, ephritis edema.
Selfheal: bitter, pungent, cold in nature.Return liver, gallbladder channel." have and relieve inflammation or internal heat, improving eyesight, dissipating bind, effect of detumescence, cures mainly red eye, swell pain, and order pearl nyctalgia, has a headache dizzy, scrofula, goiter and tumor, swells and ache; Thyroid gland enlargement, scrofula, the proliferation of mammary gland, the card such as hypertension, hyperglycaemia, high fat of blood and high blood are sticky.
Akebi: hardship, cold in nature.Thoughts of returning home warp, small intestinl channel, urinary bladder channel.Function inducing diuresis for treating strangurtia, the relieving restlessness that clears away heart-fire, the lactogenesis of stimulating the menstrual flow.For stranguria, oedema, vexed urine is red, few through closing breast, damp-heat arthralgia pain.This product energy inducing diuresis for removing edema, lower dampness removing heat, makes that damp and hot heresy is descending discharges from urine.
Umbellate pore furgus: taste is sweet, light, flat.The thoughts of returning home, spleen, stomach, lung, kidney, warp.Control difficult urination, oedema, have loose bowels, stranguria with turbid discharge, under band.
Rhizoma alismatis: taste is sweet, light, cold in nature.Return kidney, urinary bladder channel.There is clearing damp and promoting diuresis, the lung that clears away heart-fire, rush down effect of kidney fire.Be mainly used in insufficiency of the spleen retention of water-damp, the wet anasarca of spreading unchecked of water; The tired resistance of heresy that water drink phlegm is wet, causes dizzy that lucid yang failing to raise voiced sound does not fall; The difficult urination of damp invasion of lower energizer, red short puckery pain, and the card such as jaundice with damp-heat pathogen.
Radix Glycyrrhizae: nature and flavor are sweet, flat.Return spleen, stomach, lung channel.Can beneficial gas bowl spares, relieving spasm to stop pain, moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.Main burnout food is few, thin Huang of flesh, and palpitation, stomachache loose stool, the anxious pain of four limbs contraction, hysteria, cough and asthma, abscess of throat, carbuncle sore swells and ache, infant fetal toxin, and medicine, food poisoning.
Herba Andrographitis: have clearing heat and detoxicating, anti-inflammatory, swelling and pain relieving effect.Cure mainly bacillary dysentery, urinary tract infections, acute tonsillitis, enteritis, sphagitis, pneumonia and influenza etc., external application can be treated sore furuncle poison, trauma infection contamination etc.
Rhizome of cyrtomium: nature and flavor hardship, is slightly cold.Return liver, the spleen channel.Have clearing heat and detoxicating, cooling blood and hemostasis, effect of desinsection.Can cure mainly anemopyretic cold, febrile virulent maculae; Blood-head is hemorrhage; Worm disease; This product also can be used for treating burn and scald and married woman is with inferior disease.
Paris polyphylla: bitter, cold.Return Liver Channel.There is the merit of clearing heat and detoxicating, cool liver arresting convulsion, be applicable to multiple pathopyretic ulcer, abscess of throat, mumps, venomous snake bite, frightened epilepsy, unconsciousness due to high fever etc.
Oroxylum indicum: mildly bitter flavor, sweet, cold nature.Return lung, liver, stomach warp.Relieve sore throat moistening lung, soothing liver and harmonizing stomach, expelling pus and promoting granulation.Cure mainly pharyngalgia larynx numbness, hoarseness, cough, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, sore is burst and is not held back for a long time, acute eczema.
Root of Loping Thistle: hardship, flat.Cool blood, Li Shui, dispels the wind, qi-restoratives.Control haematemesis, lower blood, oedema, weakness, traumatic injury, large carbuncle redness, pruigo, mange.
Play both sides of the street: hardship, flat.Return liver, kidney channel.Dispelling, collateral-activating, Li Shui stimulates the menstrual flow.For joint pain, numbness contracture, oedema turgor, breast is few through closing.
Shouldering plate returns: acid; Bitter; Property is put down.Return lung; Small intestinl channel.Clearing heat and detoxicating; Inducing diuresis and reducing edema; Loose stasis of blood hemostasis.Main furunculosis carbuncle is swollen; Erysipelas; The paralysis cheek; Mastitis; Ting ear; Tonsillitis; Cold, fever; Cough with lung heat; Pertussis; Scrofula; Haemorrhoids; Lymphogranuloma inguinale bubo; Rush down dysentery; Jaundice; Tympanites; Oedema; Stranguria with turbid discharge; Under band; Malaria; Wind fire cute conjunctivitis; Treating swelling and pain by traumatic injury; Spit blood; Have blood in stool; Snake bite and insect sting.
In feed, the weight portion of each component is: the Chinese medicine additive 12-16 of institute weight portion, trace element chelated dose of 2-6 weight portion, sugared brewer's yeast 0.2-0.7 weight portion, corn 46-67 weight portion, hay 41-65 weight portion, bacillus 0.4-0.9 weight portion, montmorillonite 3-5 weight portion.
Bacillus comprises one or both mixing in bacillus subtilis and bacillus licheniformis.
Trace element chelated dose comprises hemoglobin, cytochrome oxidase and cobalamin.
In Chinese medicine additive, the weight portion of each bulk drug also can be: Divine Comedy 19-31 weight portion, rice bud 13-22 weight portion, fructus amomi 21-30 weight portion, bighead atractylodes rhizome 25-32 weight portion, fevervine 13-21 weight portion, root of large-flowered skullcap 22-33 weight portion, honeysuckle 30-38 weight portion, the mountain on the other way round 16-24 weight portion that disappears, asafoetide 12-22 weight portion, raddle 16-25 weight portion, caulis bambusae in taenian 18-27 weight portion, yncaria stem with hooks 9-18 weight portion, rhizoma Gastrodiae 23-33 weight portion, rhizoma arisaematis 3-7 weight portion, borneol 19-26 weight portion, bluish dogbane 22-33 weight portion, selfheal 11-20 weight portion, akebi 30-37 weight portion, umbellate pore furgus 20-28 weight portion, rhizoma alismatis 17-26 weight portion, Radix Glycyrrhizae 14-21 weight portion, Herba Andrographitis 23-32 weight portion, rhizome of cyrtomium 5-11 weight portion, Paris polyphylla 10-18 weight portion, Oroxylum indicum 14-25 weight portion, Root of Loping Thistle 27-37 weight portion, 20-31 weight portion and shoulder plate 11-24 weight portion plays both sides of the street.
In Chinese medicine additive, the weight portion of each bulk drug can be again: Divine Comedy 21-28 weight portion, rice bud 14-21 weight portion, fructus amomi 23-28 weight portion, bighead atractylodes rhizome 26-31 weight portion, fevervine 15-20 weight portion, root of large-flowered skullcap 24-30 weight portion, honeysuckle 31-37 weight portion, the mountain on the other way round 17-22 weight portion that disappears, asafoetide 14-20 weight portion, raddle 18-23 weight portion, caulis bambusae in taenian 19-25 weight portion, yncaria stem with hooks 10-17 weight portion, rhizoma Gastrodiae 25-31 weight portion, rhizoma arisaematis 3-6 weight portion, borneol 19-24 weight portion, bluish dogbane 22-29 weight portion, selfheal 11-18 weight portion, akebi 32-37 weight portion, umbellate pore furgus 21-27 weight portion, rhizoma alismatis 17-23 weight portion, Radix Glycyrrhizae 14-18 weight portion, Herba Andrographitis 25-31 weight portion, rhizome of cyrtomium 5-9 weight portion, Paris polyphylla 10-16 weight portion, Oroxylum indicum 16-24 weight portion, Root of Loping Thistle 28-36 weight portion, 21-28 weight portion and shoulder plate and return 13-21 weight portion plays both sides of the street.
It is a kind of for preventing and treating the preparation method of feed of bowel oedema disease that the present invention also provides, and comprises the following steps:
The first step, corn, hay are dropped in mixer and mixed in proportion, adding the content of moisture in water, control mixture is 59%-82%, stir, after add in proportion brewer's yeast, bacillus, mixed material is added in horizental silo, by the material compacting mixing, cover tightly, cause the inner anaerobic environment of material, at the temperature bottom fermentation 35-40 days of 19 DEG C-30 DEG C, rear acquisition fermented product, is dried fermentation material, obtain the solid fermentation product of moisture below 7%, be ground into powder;
Second step, montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μ m;
The 3rd step, each bulk drug in Chinese medicine additive is mixed in proportion, the ethanol that to add subsequently with respect to the determining alcohol of 3 times of its quality be 73-86%, add hot reflux 2 hours, filter, filtered fluid is refrigerated at-1.0 DEG C and spend the night, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
The 4th step, the montmorillonite ultra-micro powder that the fermented product powder that the first step is obtained, second step obtain, the Chinese medicine additive powder that the 3rd step obtains and trace element chelated dose of mixing in proportion, obtain described feed.
A kind of for preventing and treating the Chinese medicine composition of bowel oedema disease, in Chinese medicine composition, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, the mountain on the other way round 14-26 weight portion that disappears, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, 18-34 weight portion and shoulder plate and return 9-27 weight portion plays both sides of the street.
For preventing and treating a Chinese medicine composition for bowel oedema disease, the preparation method of Chinese traditional medicine composition composition powders comprises:
Step 1, all bulk drugs are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add the water doubly measured with respect to its quality 5-7, boil 2-4 hour, steam pressure is that 0.6-1Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to the water doubly measured with respect to its quality 5-7, boils 2-4 hour, steam pressure is that 0.6Mpa-1Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
The toxicity test of embodiment 1 Chinese medicine composition of the present invention
Get Divine Comedy 23g, rice bud 17g, fructus amomi 25g, bighead atractylodes rhizome 27g, fevervine 16g, root of large-flowered skullcap 28g, honeysuckle 33g, mountain on the other way round disappear 19g, asafoetide 15g, raddle 23g, caulis bambusae in taenian 24g, yncaria stem with hooks 10g, rhizoma Gastrodiae 27g, rhizoma arisaematis 6g, borneol 20g, bluish dogbane 23g, selfheal 16g, akebi 34g, umbellate pore furgus 27g, rhizoma alismatis 20g, Radix Glycyrrhizae 16g, Herba Andrographitis 29g, rhizome of cyrtomium 8g, Paris polyphylla 11g, Oroxylum indicum 23g, Root of Loping Thistle 35g, 27g and shoulder plate and return 20g plays both sides of the street; After mixing, pulverize, in the mixture after pulverizing, add the water of 1500g, decocts 2.5 hours, filter, in filter residue, add the water of 650g again to decoct 1.5 hours, filter, by twice filtrate mixing, be evaporated to the decoction that crude drug concentration is 3g/ml.
Get ICR mouse, body weight is at 25-30 gram, by body weight random packet, and 10 every group, male and female half and half, oral administration solution administration, dosage is only 6.0ml/.Continuous Observation 20 days after administration, all mouse of result are strong deposits, and its activity, diet, hair, excreta are no abnormal, have no toxic reaction.Irritation test is carried out in white mouse oral cavity and damaged skin, there are no irritative response and other bad reaction.
Toxicity test proves, the not toxic effect of this medicine and bad reaction, and clinical practice is safe and reliable.
Embodiment 2 Chinese medicine composition 1 of the present invention and preparation method
Get Divine Comedy 25g, rice bud 15g, fructus amomi 28g, bighead atractylodes rhizome 30g, fevervine 19g, root of large-flowered skullcap 25g, honeysuckle 36g, mountain on the other way round disappear 21g, asafoetide 19g, raddle 18g, caulis bambusae in taenian 19g, yncaria stem with hooks 16g, rhizoma Gastrodiae 31g, rhizoma arisaematis 4, borneol 23g, bluish dogbane 28g, selfheal 12g, akebi 32g, umbellate pore furgus 22g, rhizoma alismatis 18g, Radix Glycyrrhizae 17g, Herba Andrographitis 26g, rhizome of cyrtomium 6g, Paris polyphylla 15g, Oroxylum indicum 17g, Root of Loping Thistle 30g, 22g and shoulder plate and return 14g plays both sides of the street; Drop in mixer and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add with respect to the water of 5 times of amounts of its quality, boil 2 hours, steam pressure is that 0.7Mpa processes, filter, obtain the first filtered fluid and filter residue; By the filter residue of acquisition again add with respect to the water of 6 times of amounts of its quality, to boil 3 hours, steam pressure be that 0.8Mpa processes, filter and obtain the second filtered fluid and filter residue; The first filtered fluid and the second filtered fluid are merged, concentrate and remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
Embodiment 3 Chinese medicine composition 2 of the present invention and preparation method
Get Divine Comedy 26g, rice bud 20g, fructus amomi 23g, bighead atractylodes rhizome 31g, fevervine 18g, root of large-flowered skullcap 29g, honeysuckle 31g, mountain on the other way round disappear 20g, asafoetide 16g, raddle 22g, caulis bambusae in taenian 25g, yncaria stem with hooks 15g, rhizoma Gastrodiae 30g, rhizoma arisaematis 5, borneol 19g, bluish dogbane 27g, selfheal 17g, akebi 36g, umbellate pore furgus 24g, rhizoma alismatis 22g, Radix Glycyrrhizae 18g, Herba Andrographitis 30g, rhizome of cyrtomium 5g, Paris polyphylla 13g, Oroxylum indicum 20g, Root of Loping Thistle 29g, 24g and shoulder plate and return 16g plays both sides of the street; Drop in mixer and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add with respect to the water of 7 times of amounts of its quality, boil 4 hours, steam pressure is that 0.8Mpa processes, filter, obtain the first filtered fluid and filter residue; By the filter residue of acquisition again add with respect to the water of 5 times of amounts of its quality, to boil 2 hours, steam pressure be that 0.9Mpa processes, filter and obtain the second filtered fluid and filter residue; The first filtered fluid and the second filtered fluid are merged, concentrate and remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
Embodiment 4 Chinese medicine composition 3 of the present invention and preparation method
Get Divine Comedy 21g, rice bud 14g, fructus amomi 27g, bighead atractylodes rhizome 26g, fevervine 15g, root of large-flowered skullcap 30g, honeysuckle 35g, mountain on the other way round disappear 22g, asafoetide 18g, raddle 21g, caulis bambusae in taenian 20g, yncaria stem with hooks 13g, rhizoma Gastrodiae 25g, rhizoma arisaematis 3, borneol 22g, bluish dogbane 24g, selfheal 18g, akebi 33g, umbellate pore furgus 26g, rhizoma alismatis 23g, Radix Glycyrrhizae 15g, Herba Andrographitis 31g, rhizome of cyrtomium 7g, Paris polyphylla 14g, Oroxylum indicum 24g, Root of Loping Thistle 28g, 26g and shoulder plate and return 18g plays both sides of the street; Drop in mixer and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add with respect to the water of 5 times of amounts of its quality, boil 2 hours, steam pressure is that 0.9Mpa processes, filter, obtain the first filtered fluid and filter residue; By the filter residue of acquisition again add with respect to the water of 7 times of amounts of its quality, to boil 4 hours, steam pressure be that 0.6Mpa processes, filter and obtain the second filtered fluid and filter residue; The first filtered fluid and the second filtered fluid are merged, concentrate and remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
Embodiment 5 feed 1 of the present invention and preparation method
A kind of feed, comprises Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus; In feed, the weight portion of each component is: Chinese medicine additive 13 weight portions, trace element chelated dose of 3 weight portion, sugared brewer's yeast 0.7 weight portion, corn 60 weight portions, hay 45 weight portions, bacillus 0.8 weight portion, montmorillonite 3 weight portions.
Bacillus is bacillus subtilis.
Trace element chelated dose is hemoglobin, cytochrome oxidase and cobalamin.
The preparation method of feed, comprises the following steps:
The first step, drops into corn, hay in mixer and mixes in proportion, and adding the content of moisture in water, control mixture is 80%, stir, after add in proportion brewer's yeast, bacillus, mixed material is added in horizental silo, by the material compacting mixing, cover tightly, cause the inner anaerobic environment of material, the temperature bottom fermentations of 30 DEG C 35 days, rear acquisition fermented product, was dried fermentation material, obtain moisture at 6% solid fermentation product, be ground into powder;
Second step, described montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μ m;
The 3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, the ethanol that to add subsequently with respect to the determining alcohol of 3 times of its quality be 75%, add hot reflux 2 hours, filter, filtered fluid is refrigerated at-1.0 DEG C and spend the night, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
The 4th step, the montmorillonite ultra-micro powder that the fermented product powder that the first step is obtained, second step obtain, the Chinese medicine additive powder that the 3rd step obtains and trace element chelated dose of mixing in proportion, obtain described feed.
Embodiment 6 feed 2 of the present invention and preparation method
A kind of feed, comprises Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus; In feed, the weight portion of each component is: Chinese medicine additive 16 weight portions, trace element chelated dose of 3 weight portion, sugared brewer's yeast 0.5 weight portion, corn 50 weight portions, hay 55 weight portions, bacillus 0.6 weight portion, montmorillonite 4 weight portions.
Bacillus is two kinds of mixing in bacillus subtilis and bacillus licheniformis.
Trace element chelated dose is the mixture of hemoglobin, cytochrome oxidase and cobalamin.
The preparation method of feed, comprises the following steps:
The first step, drops into corn, hay in mixer and mixes in proportion, and adding the content of moisture in water, control mixture is 62%, stir, after add in proportion brewer's yeast, bacillus, mixed material is added in horizental silo, by the material compacting mixing, cover tightly, cause the inner anaerobic environment of material, the temperature bottom fermentations of 25 DEG C 35 days, rear acquisition fermented product, was dried fermentation material, obtain moisture at 5% solid fermentation product, be ground into powder;
Second step, montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μ m;
The 3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, the ethanol that to add subsequently with respect to the determining alcohol of 3 times of its quality be 80%, add hot reflux 2 hours, filter, filtered fluid is refrigerated at-1.0 DEG C and spend the night, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
The 4th step, the montmorillonite ultra-micro powder that the fermented product powder that the first step is obtained, second step obtain, the Chinese medicine additive powder that the 3rd step obtains and trace element chelated dose of mixing in proportion, obtain described feed.
Embodiment 7 clinical testings
(1) for examination animal
Choose the hybridization piggy of 120 natural occurrences in Changsha diversified farm pig farm as treatment contrast test object; Separately from Changsha diversified farm pig farm, choose at random 80 healthy hybridization piggys as prevention contrast test object.
(2) bacterial strain extracts and cultivates:
The aseptic pork liver of dying of illness, lymph node, lung, small intestine leading portion content got carries out respectively contact, gram stain microscopy, visible Gram-negative dialister bacterium.Lymph node, small intestine leading portion content are inoculated in cultured solution of broth, for subsequent use.Cultured solution of broth is evenly muddy, has canescence emplastic precipitation.Visible grey on nutrient agar, slightly transparent, circular protrusions, the irregular bacterium colony in edge.Culture is smear respectively, gram stain microscopy, visible single or arrangement in pairs, the Gram-negative dialister bacterium of the blunt circle in two ends.
(3) prevention contrast experiment:
80 health pig of random choose are divided into 2 groups (control group 1 and embodiment groups) at random, wherein, control group 1 uses traditional pig feed pig of feeding, embodiment group is used the pig of feeding of the feed 1 in embodiment 5, feed after 20 days, control group 1 and embodiment group are carried out to the 5 times dilutions of artificial challenge with culture for subsequent use, lumbar injection 0.2mL/kg, observed and recorded is respectively organized the incidence of disease and the death rate of pig, and result is as shown in table 1.
The table 1 preventive effect table of comparisons
Data from table 1: the feed that the present invention contains Chinese medicine composition has obvious preventive effect to bowel oedema disease.
(4) treatment contrast test:
Curative effect determinate standard
Recovery from illness: after medication, the position oedema such as nervous symptoms and face, eyelid disappear, spirit, appetite recover normal, not recurrence in first quarter moon.
Take a turn for the better: after medication, symptom alleviates, spirit, appetite take a turn for the better.
Invalid: after medication, to maintain former symptom or increase the weight of.
Efficient is cure rate and improvement rate sum.
120 sick pigs choosing are at random divided into 3 groups (treatment by Chinese herbs group, western medicine group, blank groups) at random, treat with different medicines, wherein, treatment by Chinese herbs group is selected the Chinese medicine composition 3 of embodiment 4, dose be every every day 0.8g/kg, treat 5 days; Western medicine group selects enrofloxacin injection 0.2ml/kg to carry out neck injection, treats 5 days; Blank group is not fed any medicine.Observed and recorded is respectively organized cure rate and the death rate of pig, and result is as shown in table 2.
The table 2 result for the treatment of table of comparisons
Data from table 2: Chinese medicine composition of the present invention is obviously better than western medicine group to the result for the treatment of of bowel oedema disease, reduce the death rate, improve cure rate.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. for preventing and treating a feed for bowel oedema disease, it is characterized in that, comprise Chinese medicine additive, montmorillonite, brewer's yeast, trace element chelated dose, corn, hay, bacillus, in described Chinese medicine additive, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, the mountain on the other way round 14-26 weight portion that disappears, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, 18-34 weight portion and shoulder plate and return 9-27 weight portion plays both sides of the street.
2. according to claim 1 for preventing and treating the feed of bowel oedema disease, it is characterized in that, in described feed, the weight portion of each component is: described Chinese medicine additive 12-16 weight portion, trace element chelated dose of 2-6 weight portion, sugared brewer's yeast 0.2-0.7 weight portion, corn 46-67 weight portion, hay 41-65 weight portion, bacillus 0.4-0.9 weight portion, montmorillonite 3-5 weight portion.
3. according to claim 1ly it is characterized in that for preventing and treating the feed of bowel oedema disease, described bacillus comprises one or both mixing in bacillus subtilis and bacillus licheniformis.
4. according to claim 1ly it is characterized in that for preventing and treating the feed of bowel oedema disease, described trace element chelated dose comprises hemoglobin, cytochrome oxidase and Cobastab
12.
5. arbitrary described for preventing and treating the feed of bowel oedema disease according to claim 1-4, it is characterized in that, in described Chinese medicine additive, the weight portion of each bulk drug is: Divine Comedy 19-31 weight portion, rice bud 13-22 weight portion, fructus amomi 21-30 weight portion, bighead atractylodes rhizome 25-32 weight portion, fevervine 13-21 weight portion, root of large-flowered skullcap 22-33 weight portion, honeysuckle 30-38 weight portion, the mountain on the other way round 16-24 weight portion that disappears, asafoetide 12-22 weight portion, raddle 16-25 weight portion, caulis bambusae in taenian 18-27 weight portion, yncaria stem with hooks 9-18 weight portion, rhizoma Gastrodiae 23-33 weight portion, rhizoma arisaematis 3-7 weight portion, borneol 19-26 weight portion, bluish dogbane 22-33 weight portion, selfheal 11-20 weight portion, akebi 30-37 weight portion, umbellate pore furgus 20-28 weight portion, rhizoma alismatis 17-26 weight portion, Radix Glycyrrhizae 14-21 weight portion, Herba Andrographitis 23-32 weight portion, rhizome of cyrtomium 5-11 weight portion, Paris polyphylla 10-18 weight portion, Oroxylum indicum 14-25 weight portion, Root of Loping Thistle 27-37 weight portion, 20-31 weight portion and shoulder plate 11-24 weight portion plays both sides of the street.
6. arbitrary described for preventing and treating the feed of bowel oedema disease according to claim 1-4, it is characterized in that, in described Chinese medicine additive, the weight portion of each bulk drug is: Divine Comedy 21-28 weight portion, rice bud 14-21 weight portion, fructus amomi 23-28 weight portion, bighead atractylodes rhizome 26-31 weight portion, fevervine 15-20 weight portion, root of large-flowered skullcap 24-30 weight portion, honeysuckle 31-37 weight portion, the mountain on the other way round 17-22 weight portion that disappears, asafoetide 14-20 weight portion, raddle 18-23 weight portion, caulis bambusae in taenian 19-25 weight portion, yncaria stem with hooks 10-17 weight portion, rhizoma Gastrodiae 25-31 weight portion, rhizoma arisaematis 3-6 weight portion, borneol 19-24 weight portion, bluish dogbane 22-29 weight portion, selfheal 11-18 weight portion, akebi 32-37 weight portion, umbellate pore furgus 21-27 weight portion, rhizoma alismatis 17-23 weight portion, Radix Glycyrrhizae 14-18 weight portion, Herba Andrographitis 25-31 weight portion, rhizome of cyrtomium 5-9 weight portion, Paris polyphylla 10-16 weight portion, Oroxylum indicum 16-24 weight portion, Root of Loping Thistle 28-36 weight portion, 21-28 weight portion and shoulder plate and return 13-21 weight portion plays both sides of the street.
7. arbitrary described for preventing and treating the preparation method of feed of bowel oedema disease according to claim 1-6, comprise the following steps:
The first step, corn, hay are dropped in mixer and mixed in proportion, adding the content of moisture in water, control mixture is 59%-82%, stir, after add in proportion brewer's yeast, bacillus, mixed material is added in horizental silo, by the material compacting mixing, cover tightly, cause the inner anaerobic environment of material, at the temperature bottom fermentation 35-40 days of 19 DEG C-30 DEG C, rear acquisition fermented product, is dried fermentation material, obtain the solid fermentation product of moisture below 7%, be ground into powder;
Second step, described montmorillonite adopts micronizer to be ground into the ultra-micro powder of 16-31 μ m;
The 3rd step, each bulk drug in described Chinese medicine additive is mixed in proportion, the ethanol that to add subsequently with respect to the determining alcohol of 3 times of its quality be 73-86%, add hot reflux 2 hours, filter, filtered fluid is refrigerated at-1.0 DEG C and spend the night, again filter, decompression recycling ethanol, is ground into powder, obtains Chinese medicine additive powder;
The 4th step, the montmorillonite ultra-micro powder that the fermented product powder that the first step is obtained, second step obtain, the Chinese medicine additive powder that the 3rd step obtains and trace element chelated dose of mixing in proportion, obtain described feed.
8. one kind for preventing and treating the Chinese medicine composition of bowel oedema disease, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of each bulk drug is: Divine Comedy 16-35 weight portion, rice bud 11-25 weight portion, fructus amomi 19-32 weight portion, bighead atractylodes rhizome 23-34 weight portion, fevervine 10-25 weight portion, root of large-flowered skullcap 20-36 weight portion, honeysuckle 28-40 weight portion, the mountain on the other way round 14-26 weight portion that disappears, asafoetide 10-24 weight portion, raddle 14-28 weight portion, caulis bambusae in taenian 15-30 weight portion, yncaria stem with hooks 7-21 weight portion, rhizoma Gastrodiae 21-35 weight portion, rhizoma arisaematis 3-8 weight portion, borneol 16-28 weight portion, bluish dogbane 20-35 weight portion, selfheal 9-23 weight portion, akebi 28-40 weight portion, umbellate pore furgus 18-30 weight portion, rhizoma alismatis 15-28 weight portion, Radix Glycyrrhizae 12-24 weight portion, Herba Andrographitis 21-34 weight portion, rhizome of cyrtomium 5-13 weight portion, Paris polyphylla 8-21 weight portion, Oroxylum indicum 12-28 weight portion, Root of Loping Thistle 25-39 weight portion, 18-34 weight portion and shoulder plate and return 9-27 weight portion plays both sides of the street.
9. according to claim 8ly it is characterized in that for preventing and treating the Chinese medicine composition of bowel oedema disease, the preparation method of described Chinese traditional medicine composition composition powders comprises:
Step 1, all bulk drugs are dropped in mixer in proportion and stir, mix, after send in pulverizer and to pulverize, the Chinese medicine composition after pulverizing is packed in multi-function extractor, add the water doubly measured with respect to its quality 5-7, boil 2-4 hour, steam pressure is that 0.6-1Mpa processes, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition is again added to the water doubly measured with respect to its quality 5-7, boils 2-4 hour, steam pressure is that 0.6Mpa-1Mpa processes, and filters and obtains the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid are merged, concentratedly remove moisture, obtain and get dry extract, adopt super-fine powder mill to pulverize, be crushed to below 30 μ m, obtain Chinese medicine additive powder.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105285417A (en) * | 2015-12-04 | 2016-02-03 | 山东新希望六和集团有限公司 | Formula feed for piglets and preparation method thereof |
| CN105341410A (en) * | 2015-11-07 | 2016-02-24 | 黑龙江省农业科学院畜牧研究所 | Feed additive for preventing and curing pig rheumatism as well as preparation method and application thereof |
| CN105456592A (en) * | 2015-12-31 | 2016-04-06 | 张明 | Traditional Chinese medicine composition for treating swine malignant edema |
| CN105816612A (en) * | 2016-04-27 | 2016-08-03 | 吴定文 | Decoction for relieving prenatal excessive swelling of ewes and processing method of decoction |
| CN106071229A (en) * | 2016-06-21 | 2016-11-09 | 山东新希望六和集团有限公司 | A kind of winter raises pigs and uses feed additive |
| CN106721325A (en) * | 2017-02-09 | 2017-05-31 | 安徽菲扬农业科技有限公司 | A kind of feed for preventing and treating bowel oedema disease |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105341410A (en) * | 2015-11-07 | 2016-02-24 | 黑龙江省农业科学院畜牧研究所 | Feed additive for preventing and curing pig rheumatism as well as preparation method and application thereof |
| CN105285417A (en) * | 2015-12-04 | 2016-02-03 | 山东新希望六和集团有限公司 | Formula feed for piglets and preparation method thereof |
| CN105456592A (en) * | 2015-12-31 | 2016-04-06 | 张明 | Traditional Chinese medicine composition for treating swine malignant edema |
| CN105816612A (en) * | 2016-04-27 | 2016-08-03 | 吴定文 | Decoction for relieving prenatal excessive swelling of ewes and processing method of decoction |
| CN106071229A (en) * | 2016-06-21 | 2016-11-09 | 山东新希望六和集团有限公司 | A kind of winter raises pigs and uses feed additive |
| CN106721325A (en) * | 2017-02-09 | 2017-05-31 | 安徽菲扬农业科技有限公司 | A kind of feed for preventing and treating bowel oedema disease |
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