CN103920159B - 涂布组合物、含药物颗粒、固体制剂和用于制备含药物颗粒的方法 - Google Patents

涂布组合物、含药物颗粒、固体制剂和用于制备含药物颗粒的方法 Download PDF

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Publication number
CN103920159B
CN103920159B CN201410012737.5A CN201410012737A CN103920159B CN 103920159 B CN103920159 B CN 103920159B CN 201410012737 A CN201410012737 A CN 201410012737A CN 103920159 B CN103920159 B CN 103920159B
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China
Prior art keywords
drug
weight
coating
parts
coating composition
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CN201410012737.5A
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English (en)
Chinese (zh)
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CN103920159A (zh
Inventor
横泽拓也
西山裕
西山裕一
丸山直亮
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Shin-Etsu Chemical Co Ltd
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Shin-Etsu Chemical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D101/00—Coating compositions based on cellulose, modified cellulose, or cellulose derivatives
    • C09D101/08—Cellulose derivatives
    • C09D101/32—Cellulose ether-esters

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Paints Or Removers (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201410012737.5A 2013-01-11 2014-01-10 涂布组合物、含药物颗粒、固体制剂和用于制备含药物颗粒的方法 Active CN103920159B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013-003534 2013-01-11
JP2013003534A JP5836980B2 (ja) 2013-01-11 2013-01-11 薬物含有粒子、固形製剤及び薬物含有粒子の製造方法

Publications (2)

Publication Number Publication Date
CN103920159A CN103920159A (zh) 2014-07-16
CN103920159B true CN103920159B (zh) 2018-01-16

Family

ID=49885183

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CN201410012737.5A Active CN103920159B (zh) 2013-01-11 2014-01-10 涂布组合物、含药物颗粒、固体制剂和用于制备含药物颗粒的方法

Country Status (6)

Country Link
US (1) US11052051B2 (enExample)
EP (1) EP2754438B2 (enExample)
JP (1) JP5836980B2 (enExample)
KR (1) KR101911977B1 (enExample)
CN (1) CN103920159B (enExample)
IN (1) IN2014DE00037A (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6203702B2 (ja) * 2014-11-18 2017-09-27 信越化学工業株式会社 ヒプロメロース酢酸エステルコハク酸エステルを用いたスプレードライ用溶液及び固体分散体の製造方法
EP3216807B2 (en) 2016-03-09 2022-05-18 Shin-Etsu Chemical Co., Ltd. Coating composition containing methyl cellulose, method for producing the same, and solid preparation
JP2018141239A (ja) 2017-02-28 2018-09-13 Ｄｏｗａエレクトロニクス株式会社 銀ナノワイヤインク
US20220218617A1 (en) * 2019-04-22 2022-07-14 Nipro Corporation Method for manufacturing pharmaceutical preparation
JP7165626B2 (ja) * 2019-06-06 2022-11-04 信越化学工業株式会社 インクジェット印刷を行う錠剤向けのコーティング用組成物、これを用いた水性インクによる印字を有する錠剤及びその製造方法
JP7399060B2 (ja) * 2020-10-01 2023-12-15 信越化学工業株式会社 ヒドロキシプロピルメチルセルロースアセテートサクシネートの製造方法
JP7399061B2 (ja) * 2020-10-01 2023-12-15 信越化学工業株式会社 ヒドロキシプロピルメチルセルロースフタレートの製造方法
WO2025187709A1 (ja) * 2024-03-08 2025-09-12 キャプシュゲル・ベルジウム・エヌ・ヴィ 可食性インク組成物

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2002096392A1 (en) * 2001-05-31 2002-12-05 Cima Labs Inc. Taste-masking of highly water-soluble drugs

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US2510923A (en) * 1945-03-03 1950-06-06 Gen Mills Inc Recording sound on wire
JP2773959B2 (ja) * 1990-07-10 1998-07-09 信越化学工業株式会社 大腸内放出性固形製剤
JP2916978B2 (ja) 1993-08-25 1999-07-05 エスエス製薬株式会社 放出開始制御型製剤
US5733575A (en) 1994-10-07 1998-03-31 Bpsi Holdings, Inc. Enteric film coating compositions, method of coating therewith, and coated forms
JPH08245423A (ja) * 1995-03-06 1996-09-24 Shionogi & Co Ltd 水系腸溶性コーティング液
JP4263776B2 (ja) * 1996-08-09 2009-05-13 杏林製薬株式会社 イブジラストの徐放化経口錠剤およびその製造方法
ES2310164T3 (es) 1999-02-10 2009-01-01 Pfizer Products Inc. Dispositivo de liberacion controlada por la matriz.
US7223421B2 (en) † 2000-06-30 2007-05-29 Mcneil-Ppc, Inc. Teste masked pharmaceutical particles
AU2001266347A1 (en) 2000-07-11 2002-01-21 Shionogi And Co., Ltd. Enteric preparations containing physiologically active peptides
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BR0315731A (pt) * 2002-10-30 2005-09-06 Pharmacia Corp Comprimidos orais de liberação prolongada e métodos para fabricar e usar os mesmos
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JP2007031407A (ja) * 2005-07-29 2007-02-08 Shin Etsu Chem Co Ltd 低置換度セルロースエーテル含有コーティング用組成物及び不快な味が隠蔽されたフィルムコーティング製剤
JP4439499B2 (ja) 2005-08-01 2010-03-24 大日本住友製薬株式会社 アムロジピン含有粒子およびそれからなる口腔内崩壊錠
JP5405752B2 (ja) 2007-01-31 2014-02-05 大日本住友製薬株式会社 被覆された薬物含有粒子および該粒子を含む固形製剤
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JP4803686B2 (ja) 2010-08-31 2011-10-26 協和発酵キリン株式会社 苦味を呈する薬物を含有する顆粒および口腔内崩壊錠
JP5973347B2 (ja) 2010-08-31 2016-08-23 協和発酵キリン株式会社 口腔内崩壊錠
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Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2002096392A1 (en) * 2001-05-31 2002-12-05 Cima Labs Inc. Taste-masking of highly water-soluble drugs

Also Published As

Publication number Publication date
US11052051B2 (en) 2021-07-06
KR20140091475A (ko) 2014-07-21
JP5836980B2 (ja) 2015-12-24
JP2014133722A (ja) 2014-07-24
EP2754438A1 (en) 2014-07-16
EP2754438B2 (en) 2020-08-05
US20140199406A1 (en) 2014-07-17
CN103920159A (zh) 2014-07-16
IN2014DE00037A (enExample) 2015-05-08
KR101911977B1 (ko) 2018-10-25
EP2754438B1 (en) 2017-03-08

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