CN103906766B - 抗cd83激动剂抗体用于治疗自身免疫疾病的用途 - Google Patents

抗cd83激动剂抗体用于治疗自身免疫疾病的用途 Download PDF

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CN103906766B
CN103906766B CN201280042210.6A CN201280042210A CN103906766B CN 103906766 B CN103906766 B CN 103906766B CN 201280042210 A CN201280042210 A CN 201280042210A CN 103906766 B CN103906766 B CN 103906766B
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antibody
antibodies
amino acid
seq
acid sequence
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CN103906766A (zh
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L·迪尔
J·贝茨
T·赛
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F Huffman Lara Cutting Co Ltd
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
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  • Transplantation (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
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  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
CN201280042210.6A 2011-07-01 2012-06-29 抗cd83激动剂抗体用于治疗自身免疫疾病的用途 Expired - Fee Related CN103906766B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161504127P 2011-07-01 2011-07-01
US61/504,127 2011-07-01
JP2011-285585 2011-12-27
JP2011285585A JP2013040160A (ja) 2011-07-01 2011-12-27 自己免疫疾患を治療するための抗ｃｄ８３アゴニスト抗体の使用
PCT/US2012/045142 WO2013006505A1 (en) 2011-07-01 2012-06-29 Use of anti-cd83 agonist antibodies for treating autoimmune diseases

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CN103906766A CN103906766A (zh) 2014-07-02
CN103906766B true CN103906766B (zh) 2017-03-08

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US (1) US9562097B2 (enExample)
EP (1) EP2726509B1 (enExample)
JP (2) JP2013040160A (enExample)
KR (1) KR20140051272A (enExample)
CN (1) CN103906766B (enExample)
AU (1) AU2012279175B2 (enExample)
BR (1) BR112013033968A2 (enExample)
CA (1) CA2840426A1 (enExample)
MX (1) MX2014000142A (enExample)
RU (1) RU2014103498A (enExample)
WO (1) WO2013006505A1 (enExample)

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JP2013150592A (ja) * 2011-07-01 2013-08-08 Genentech Inc 自己免疫疾患を治療するための抗ｃｄ８３アゴニスト抗体の使用
JP2013040160A (ja) 2011-07-01 2013-02-28 Genentech Inc 自己免疫疾患を治療するための抗ｃｄ８３アゴニスト抗体の使用
PT2951208T (pt) * 2013-02-01 2019-12-30 Univ California Anticorpos anti-cd83 e sua utilização
CA2965170A1 (en) * 2014-10-23 2016-04-28 Dendrocyte Biotech Pty Ltd Cd83 binding proteins and uses thereof
US9982057B2 (en) 2014-11-17 2018-05-29 Pelican Therapeutics, Inc. Human TNFRSF25 antibody
CN104610452B (zh) * 2015-01-27 2018-11-20 中国科学技术大学先进技术研究院 抗人cd83单克隆抗体及其制备、鉴定和应用
SG11201810853UA (en) 2016-06-09 2019-01-30 Pelican Therapeutics Inc Anti-tnfrsf25 antibodies
US11192943B2 (en) * 2017-09-30 2021-12-07 Hefei Lifeon Pharmaceutical Co., Ltd. Protein binding to fibronectin B domain
US12492254B2 (en) * 2018-02-23 2025-12-09 H. Lee Moffitt Cancer Center and Research Intitute. Inc. CD83-binding chimeric antigen receptors
JP7701908B2 (ja) * 2019-08-16 2025-07-02 エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド 抗ｃｄ３８キメラ抗原受容体を発現する制御性ｔ細胞
CN114929341A (zh) * 2019-08-16 2022-08-19 H.李.莫菲特癌症中心和研究所股份有限公司 用于治疗髓系恶性肿瘤的嵌合抗原受体
WO2021127212A2 (en) * 2019-12-18 2021-06-24 H. Lee Moffitt Cancer Center And Research Institute Inc. Systems and methods for producing efficacious regulatory t cells
EP3895723A1 (en) 2020-04-16 2021-10-20 Friedrich-Alexander-Universität Erlangen-Nürnberg Scd83 for wound healing, hair growth, and skin and hair care
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EP2726509A4 (en) 2015-01-28
AU2012279175A1 (en) 2013-05-02
HK1199271A1 (en) 2015-06-26
AU2012279175B2 (en) 2017-02-02
US20140286950A1 (en) 2014-09-25
KR20140051272A (ko) 2014-04-30
JP2015511931A (ja) 2015-04-23
EP2726509A1 (en) 2014-05-07
EP2726509B1 (en) 2018-05-02
MX2014000142A (es) 2014-04-25
RU2014103498A (ru) 2015-08-10
CA2840426A1 (en) 2013-01-10
WO2013006505A1 (en) 2013-01-10
BR112013033968A2 (pt) 2017-12-12
JP6198730B2 (ja) 2017-09-20
JP2013040160A (ja) 2013-02-28
US9562097B2 (en) 2017-02-07
CN103906766A (zh) 2014-07-02

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