CN103830593A - Chinese medicinal composition for treating burns and scalds and externally applied medicament thereof - Google Patents

Chinese medicinal composition for treating burns and scalds and externally applied medicament thereof Download PDF

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CN103830593A
CN103830593A CN201410110640.8A CN201410110640A CN103830593A CN 103830593 A CN103830593 A CN 103830593A CN 201410110640 A CN201410110640 A CN 201410110640A CN 103830593 A CN103830593 A CN 103830593A
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CN103830593B (en
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吴兴寿
吴欢欢
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Abstract

The invention discloses a Chinese medicinal composition for treating burns and scalds and an externally applied medicament thereof. The Chinese medicinal composition for treating burns and scalds is mainly prepared from the following raw materials in parts by weight: 20-50 parts of borneol, 20-50 parts of thinleaf milkwort root-bark, 20-50 parts of Chinese angelica, 10-40 parts of fineleaf schizonepeta herb, 15-50 parts of carbonized sanguisorba root, 15-45 parts of selinum japenious seed, 15-45 parts of dangshen, 15-45 parts of raw white paeony root, 10-50 parts of Indian buead, 10-50 parts of garden balsam stem, 10-50 parts of barbary wolfberry fruit, 10-50 parts of Chinese wolfberry root-bark, 10-50 parts of tall gastrodia tuber, 10-50 parts of dried orange peel, 20-50 parts of cochinchina momordica seed and 20-50 parts of garter snake. The Chinese medicinal composition for treating burns and scalds and the externally-applied medicament thereof are free of simulation, have no toxic or side effects, are high in safety, do not cause irritability, and can be used for effectively treating burns and scalds and effectively restoring wounded skin to normal without skin peeling, pain, skin grafting and scar. The effective rate is 100 percent and the curative rate is 60 percent.

Description

A kind of Chinese medicine composition and external medicinal liquid thereof for the treatment of burn and scald
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine composition and external medicinal liquid thereof of the treatment burn and scald of preparing with pure plant material.
Technical background
In daily life, the skin burn or the scald that accidentally cause because taking action often can occur, even exfoliation necrosis that the lighter's pain is rubescent, severe one is bubbled, hinders to bone.As cured not in time, pathogenic factor and antibacterial are invaded, and not only can expand wound surface, and skin ulceration, even causes infection, produce septicemia, cause death.The medicine that at present treatment is scalded is a lot, but slow, the weak effect of generally taking effect, can not normal healing, infection suppurates even, scar.Chinese patent CN101721535A discloses a kind of preparation and application for the treatment of burn and scald medicine for external use, taking Radix Sanguisorbae, the Radix Angelicae Dahuricae, white Adeps Serpentis, powder, fresh ground Indigo Naturalis, Radix Codonopsis, ground beetle, Squama Manis, Herba Saussureae Involueratae and Ovum Gallus domesticus album as major ingredient; Be equipped with Rhizoma Coptidis, Radix Ophiopogonis pain, dog oil, Radix Rehmanniae, Radix Angelicae Sinensis, Flos Carthami, Radix Et Rhizoma Rhei, Borneolum Syntheticum, process, play heat clearing away, removing toxic substances, antiinflammatory, healed, grown the medical effect of muscle, but raw materials used more, preparation method is loaded down with trivial details, in therapeutic process, can not avoid pain, can not effectively avoid cicatrix, recover injury skin.
Summary of the invention
The object of this invention is to provide one and can effectively treat burn and scald, in therapeutic process, need not take off skin, there is no pain, do not need skin-grafting, preventing from scar, can have the Chinese medicine composition of efficient recovery injury skin to former state.
Another object of the present invention is to provide the external medicinal liquid being made by the Chinese medicine composition of this treatment burn and scald.
The Chinese medicine composition for the treatment of burn and scald of the present invention, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50.
The Chinese medicine composition for the treatment of burn and scald of the present invention, not only can treat burn and scald, can also treat the dermatosis such as herpes.
The Chinese medicine composition for the treatment of burn and scald of the present invention, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 30-40, Radix Polygalae 30-40, Radix Angelicae Sinensis 30-40, Herba Schizonepetae 20-30, charred Radix Sanguisorbae 20-40, Fructus Cnidii 20-40, Radix Codonopsis 20-40, Radix Paeoniae Alba 20-40, Poria 20-40, Herba speranskiae tuberculatae 20-40, Fructus Lycii 20-40, Cortex Lycii 20-40, Rhizoma Gastrodiae 20-40, Pericarpium Citri Reticulatae 20-40, Semen Momordicae 30-40, black Serpentis 30-40.
The Chinese medicine composition for the treatment of burn and scald of the present invention, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 35, Radix Polygalae 35, Radix Angelicae Sinensis 35, Herba Schizonepetae 25, charred Radix Sanguisorbae 30, Fructus Cnidii 30, Radix Codonopsis 30, Radix Paeoniae Alba 30, Poria 30, Herba speranskiae tuberculatae 30, Fructus Lycii 30, Cortex Lycii 30, Rhizoma Gastrodiae 30, Pericarpium Citri Reticulatae 30, Semen Momordicae 35, black Serpentis 35.
Described Chinese medicine composition can be made medicine for external use, also can make oral medicine.
Patient, using in the process of the dermatosis such as described traditional Chinese medicine composition for treating burn and scald, forbids edible Rhizoma Zingiberis Recens, raw Bulbus Allii, also forbids edible Herba Coriandri, Fructus Capsici (Herba Coriandri, raw ripe all the banning use of of Fructus Capsici).
The external medicinal liquid that the Chinese medicine composition for the treatment of burn and scald of the present invention makes, described external medicinal liquid comprises the composition of following weight portion:
Figure BDA0000481017180000021
The external medicinal liquid being made by the Chinese medicine composition for the treatment of burn and scald of the present invention, in treatment burn and scald process, the wounded does not have pain, does not need skin-grafting, preventing from scar, can have efficient recovery injury skin to former state.
External medicinal liquid of the present invention, described Chinese liquor is 40-70 degree, described external medicinal liquid also comprises that parts by weight are the glycerol of 2-6.
The Chinese liquor of 40-70 degree can effectively ensure the therapeutic effect of external medicinal liquid, again can effective sterilizing, and avoid burn and scald face to infect.
Adding of glycerol, can ensure, smearing in the process of external medicinal liquid treatment burn and scald, can ensure therapeutic effect, can avoid again the dry and cracked of burn and scald injury skin, keeps moistening, and strengthens therapeutic effect.
External medicinal liquid of the present invention, described external medicinal liquid comprises the composition of following weight portion:
Figure BDA0000481017180000031
The preparation method of Chinese medicine composition of the present invention, comprises the steps:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 30-55 DEG C decocts 3-6h, merges three times decocting liquid, filters to get filtrate; 40-50 DEG C of concentrated described filtrate, concentrated 0.5-1.5h obtains the extractum that relative density is 1.20-1.25; The ethanol that adds 90%-95% carries out precipitate with ethanol, reclaims ethanol concentrated, dry at 45-50 DEG C, makes fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol that 6-10 doubly measures 90%-95%, 40-60 DEG C of reflux, extract, 3-4h, reclaim ethanol concentrated, dry at 40-50 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
The preparation method of Chinese medicine composition of the present invention, principle is simple, easy to operate.
The preparation method of Chinese medicine composition of the present invention, comprises the steps:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 40 DEG C decoct 4h, merge three times decocting liquid, filter to get filtrate; 45 DEG C of concentrated described filtrates, concentrated 1h obtains the extractum that relative density is 1.20-1.25; Add 95% ethanol and carry out precipitate with ethanol, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol of 8 times of amounts 95%, 50 DEG C of reflux, extract, 3.5h, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
The preparation method of external medicinal liquid of the present invention, comprises the steps:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) to the Chinese liquor that adds 10-20 doubly to measure in described Chinese medicine composition, stir, obtain Chinese medicine composition solution;
C) to the potassium sorbate and the L MALIC ACID that add described weight portion in described Chinese medicine composition solution, stir, and room temperature places 2-5 days, must treat the external medicinal liquid of burn and scald;
D) the external medicinal liquid sterilizing, the bottling that step c) are obtained.
The preparation method of external medicinal liquid of the present invention, principle is simple, easy to operate.
The preparation method of external medicinal liquid of the present invention, comprises the steps:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) to the Chinese liquor that adds 15 times of amounts in described Chinese medicine composition, stir, obtain Chinese medicine composition solution 1;
C) to the glycerol that adds described weight portion in described Chinese medicine composition solution 1, stir, obtain Chinese medicine composition solution 2;
D) to the potassium sorbate and the L MALIC ACID that add described weight portion in described Chinese medicine composition solution 2, stir, and room temperature places 3 days, must treat the external medicinal liquid of burn and scald;
E) the external medicinal liquid sterilizing, the bottling that step d) are obtained.
When external external medicinal liquid of the present invention, can not at will touch wound, can inject a small amount of medicinal liquid by needle tubing, only need once, as the wounded has touched the bubble in the condition of the injury, also not take off skin, directly medicine-feeding.
External medicinal liquid of the present invention, can also prepare in accordance with the following methods:
Ratio of component takes each raw material (Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50) by weight, and be immersed in the Chinese liquor of the 40-70 degree that 5-10 doubly measures, shady place is preserved 15 days, to obtain final product.
Source raw materials used in the present invention is as follows:
Borneolum Syntheticum (Dipterocarpaceae): the resin of Spore density Borneolum Syntheticum and volatile oil processed goods extract the crystallization obtaining.Acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has the refreshment of having one's ideas straightened out, the loose poison of heat clearing away, and effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer is hoodwinked key clearly, sore throat deafness, aphtha tooth is swollen, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Radix Polygalae (Polygala tenuifolia Willd.): Polygalaceae rogation flower dicotyledon.Warm in nature, bitter in the mouth, pungent, the function of there is the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling, for heart kidney not .. hand over the insomnia and dreamful sleep causing, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Radix Angelicae Sinensis (Angelica sinensis) is the dry root of umbelliferae angelica.Sweet in the mouth, pungent, bitter, warm in nature; Return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation; Cure mainly: all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Herba Schizonepetae (Nepeta cataria L.): Labiatae, Nepeta.Taste is flat, and warm in nature, nontoxic, faint scent is dense; Enter lung, Liver Channel.Expelling pathogenic wind from the body surface, declares malicious rash, treating blood disorders relieving convulsion; Cure mainly flu cold and heat, headache, eye itching, pharyngalgia, cough, measles, rubella, carbuncle skin ulcer, spits blood, and clot blood, has blood in stool, metrorrhagia, postpartum apoplexy, bruise.
Charred Radix Sanguisorbae: the root of Rosaceae herbaceos perennial Radix Sanguisorbae Sanguisorba officinalis L..Bitter, sour, cool; Return liver, stomach, large intestine channel.Cooling blood for hemostasis, removing toxic substances sore.The various hemorrhage and burn due to hot liquid or fires for the treatment of heat in blood etc.Clinical many parch to black are used as medicine.
Fructus Cnidii (Cnidium monnieri(L.) Cuss.): the dry mature fruit of samphire cnidium monnieri.Warm in nature, acrid in the mouth, hardship.Warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.): the dry root of campanulaceae Codonopsis plant Radix Codonopsis, element flower Radix Codonopsis or radix codonpsis tangshen.Property is put down, sweet in the mouth, micro-acid; Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Radix Paeoniae Alba (Paeonia lactiflora Pall.): another name, the Radix Paeoniae Alba, Radix Paeoniae, Ranunculaceae, Paeonia herbaceos perennial.Cold nature, bitter in the mouth, acid; Return liver, spleen channel.The yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing the hyperactive liver sun.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat are used for having a headache.
Poria (Poria cocos Wolf): the sclerotium of On Polyporaceae Poria.Property is put down, sweet in the mouth, light; Enter the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.
Herba speranskiae tuberculatae (Garden Balsam Stem): Phrymaceae Herba speranskiae tuberculatae platymiscium.Acrid in the mouth, warm in nature; Enter Liver Channel.Expelling wind and removing dampness, promoting blood circulation and detumescence pain relieving.For rheumatic arthralgia, muscles contracture, traumatic injury, sore swollen toxin.
Fructus Lycii (FRUCTUS LYCII): the multi-branched shrub plant of Solanaceae Lycium.Sweet in the mouth, property are put down; Return liver, kidney, lung meridian.Nourishing YIN and supplementing blood, replenishing vital essence to improve eyesight.Cure mainly: asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
Cortex Lycii (Cortex Lycii): the root bark of Solanaceae, Lycium plant Fructus Lycii (Lycium chinense Mill.).Cold in nature, sweet in the mouth.Removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.
Rhizoma Gastrodiae (Gastrodia elata Bl.): the orchid family, Gastrodia herbaceos perennial.Suppressing the hyperactive liver to relieve the wind syndrome, wind-expelling pain-stopping.In order to treatment have a dizzy spell, the disease such as numb limbs and tense tendons, infantile convulsion.
Pericarpium Citri Reticulatae: the mature peel of rutaceae orange and variety thereof.Bitter in the mouth, pungent, warm in nature; Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Semen Momordicae (Momordica cochinchinensis (Lour.) Spreng.): Cucurbitaceae Fructus Momordicae charantiae book plant.Bitter, micro-sweet, cool in nature, poisonous; Return liver, spleen, stomach warp.Mass dissipating and swelling eliminating, counteracting toxic substances is treated skin ulcer.For sore swollen toxin, acute mastitis, scrofula, anal fistula, chronic eczema, tinea alba.
Black Serpentis (Zoacys dhumnades): release name, Zaocys, Zaocys.The live body of Chordata Colubridae animal Zaocys.Property sweet, flat, return Liver Channel, nontoxic.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Beneficial effect of the present invention is:
(1) adopt raw material mostly to be pure plant or the pure plant extracts that degree of safety is high, the Chinese medicine composition for the treatment of burn and scald of preparation is non-stimulated, have no side effect, degree of safety is high, allergic phenomena can not occur, can effectively treat burn and scald, need not take off skin, there is no pain, do not need skin-grafting, preventing from scar, can have the Chinese medicine composition of efficient recovery injury skin to former state in therapeutic process.
(2) Chinese medicine composition for the treatment of burn and scald of the present invention, preparation method is simple, easy to operate.
Brief description of the drawings
Fig. 1 appoints the right lower limb before certain treatment to scald face photo in model case 1;
Fig. 2 appoints the right lower limb after certain treatment to scald face photo in model case 1;
Fig. 3 is that in model case 2, the right arm before Lee's treatment is scalded face photo;
Fig. 4 is that in model case 2, the right arm after Lee's treatment is scalded face photo.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1 Chinese medicine composition
Prescription:
Borneolum Syntheticum 20g, Radix Polygalae 20g, Radix Angelicae Sinensis 20g, Herba Schizonepetae 10g, charred Radix Sanguisorbae 15g, Fructus Cnidii 15g, Radix Codonopsis 15g, Radix Paeoniae Alba 15g, Poria 10g, Herba speranskiae tuberculatae 10g, Fructus Lycii 10g, Cortex Lycii 10g, Rhizoma Gastrodiae 10g, Pericarpium Citri Reticulatae 10g, Semen Momordicae 20g, black Serpentis 20g.
Method for making:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 30 DEG C decoct 6h, merge three times decocting liquid, filter to get filtrate; 40 DEG C of concentrated described filtrates, it is 1.20 extractum that concentrated 1.5h obtains relative density; Add 90%% ethanol and carry out precipitate with ethanol, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol of 6 times of amounts 90%%, 40 DEG C of reflux, extract, 3h, reclaim ethanol concentrated, dry at 40 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
Embodiment 2 Chinese medicine compositions
Prescription:
Borneolum Syntheticum 50g, Radix Polygalae 50g, Radix Angelicae Sinensis 50g, Herba Schizonepetae 40g, charred Radix Sanguisorbae 50g, Fructus Cnidii 45g, Radix Codonopsis 45g, Radix Paeoniae Alba 45g, Poria 50g, Herba speranskiae tuberculatae 50g, Fructus Lycii 50g, Cortex Lycii 50g, Rhizoma Gastrodiae 50g, Pericarpium Citri Reticulatae 50g, Semen Momordicae 50g, black Serpentis 50g.
Method for making:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 55 DEG C decoct 3h, merge three times decocting liquid, filter to get filtrate; 50 DEG C of concentrated described filtrates, it is 1.25 extractum that concentrated 0.5h obtains relative density; Add 95% ethanol and carry out precipitate with ethanol, reclaim ethanol concentrated, dry at 50 DEG C, make fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol of 10 times of amounts 95%, 60 DEG C of reflux, extract, 4h, reclaim ethanol concentrated, dry at 50 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
Embodiment 3 Chinese medicine compositions
Prescription:
Borneolum Syntheticum 30g, Radix Polygalae 30g, Radix Angelicae Sinensis 30g, Herba Schizonepetae 20g, charred Radix Sanguisorbae 20g, Fructus Cnidii 20g, Radix Codonopsis 20g, Radix Paeoniae Alba 20g, Poria 20g, Herba speranskiae tuberculatae 20g, Fructus Lycii 20g, Cortex Lycii 20g, Rhizoma Gastrodiae 20g, Pericarpium Citri Reticulatae 20g, Semen Momordicae 30g, black Serpentis 30g.
Method for making: the preparation method according to embodiment 1 makes Chinese medicine composition.
Embodiment 4 Chinese medicine compositions
Prescription:
Borneolum Syntheticum 40g, Radix Polygalae 40g, Radix Angelicae Sinensis 40g, Herba Schizonepetae 30g, charred Radix Sanguisorbae 40g, Fructus Cnidii 40g, Radix Codonopsis 40g, Radix Paeoniae Alba 40g, Poria 40g, Herba speranskiae tuberculatae 40g, Fructus Lycii 40g, Cortex Lycii 40g, Rhizoma Gastrodiae 40g, Pericarpium Citri Reticulatae 40g, Semen Momordicae 40g, black Serpentis 40g.
Method for making: the preparation method according to embodiment 2 makes Chinese medicine composition.
Embodiment 5 Chinese medicine compositions
Prescription:
Borneolum Syntheticum 35g, Radix Polygalae 35g, Radix Angelicae Sinensis 35g, Herba Schizonepetae 25g, charred Radix Sanguisorbae 30g, Fructus Cnidii 30g, Radix Codonopsis 30g, Radix Paeoniae Alba 30g, Poria 30g, Herba speranskiae tuberculatae 30g, Fructus Lycii 30g, Cortex Lycii 30g, Rhizoma Gastrodiae 30g, Pericarpium Citri Reticulatae 30g, Semen Momordicae 35g, black Serpentis 35g.
Method for making:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 40 DEG C decoct 4h, merge three times decocting liquid, filter to get filtrate; 45 DEG C of concentrated described filtrates, it is 1.20 extractum that concentrated 1h obtains relative density; Add 95% ethanol and carry out precipitate with ethanol, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol of 8 times of amounts 95%, 50 DEG C of reflux, extract, 3.5h, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
Embodiment 6 external medicinal liquids
Prescription:
Method for making:
A) first by Chinese medicine composition, 40 degree Chinese liquor and each adjuvants by weight ratio of component weigh, for subsequent use;
B) to the Chinese liquor that adds described weight portion in described Chinese medicine composition, stir, obtain Chinese medicine composition solution;
C) to the potassium sorbate and the L MALIC ACID that add described weight portion in described Chinese medicine composition solution, stir, and room temperature places 5 days, must treat the external medicinal liquid of burn and scald;
D) the external medicinal liquid sterilizing, the bottling that step c) are obtained.
Embodiment 7 external medicinal liquids
Prescription:
Figure BDA0000481017180000111
Method for making: the external medicinal liquid that makes treatment burn and scald according to the method for embodiment 6.
Embodiment 8 external medicinal liquids
Prescription:
Method for making:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) in described Chinese medicine composition, add 70 of described weight portion to spend Chinese liquor, stir, obtain Chinese medicine composition solution 1;
C) to the glycerol that adds described weight portion in described Chinese medicine composition solution 1, stir, obtain Chinese medicine composition solution 2;
D) to the potassium sorbate and the L MALIC ACID that add described weight portion in described Chinese medicine composition solution 2, stir, and room temperature places 3 days, must treat the external medicinal liquid of burn and scald;
E) the external medicinal liquid sterilizing, the bottling that step d) are obtained.
Embodiment 9 external medicinal liquids
Prescription:
Method for making: the method according to embodiment 8 makes external medicinal liquid.
Embodiment 10 external medicinal liquids
Prescription:
Figure BDA0000481017180000122
Method for making: the method according to embodiment 8 makes external medicinal liquid.
For this situation is described, now further illustrate effect of the present invention by test example as follows:
Test example 1
Treatment group 30 examples, 3~60 years old age, average 20 years old, the course of disease 1~3 month.
Take mode: treatment group: the external medicinal liquid that external is made by the Chinese medicine composition for the treatment of burn and scald of the present invention, first use normal saline flushing, the secretions of cleaning ulcer and burn and scald face, dip the external medicinal liquid of embodiment 10 by swab stick, be applied on the burn and scald face after cleaning, every 8-10min smears once, smears continuously two hours.Matched group: external JINGWANHONG RUANGAO (composition: Radix Sanguisorbae, Radix Rehmanniae, Pericarpium Papaveris, Radix Angelicae Sinensis, Semen Persicae, Rhizoma Coptidis, Semen Momordicae, Crinis Carbonisatus, Petiolus Trachycarpi, Herba Lobeliae Chinensis, Eupolyphaga Seu Steleophaga, Radix Ampelopsis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Flos Carthami, Radix Et Rhizoma Rhei, Radix Sophorae Flavescentis, Galla Chinensis, the Flos Sophorae Immaturus, Fructus Chaenomelis, Rhizoma Atractylodis, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Scutellariae, Rhizoma Picrorhizae, Rhizoma Chuanxiong, Fructus Gardeniae, Fructus Mume, Borneolum Syntheticum, Sanguis Draxonis), clear up wound surface with normal saline, apply JINGWANHONG RUANGAO or JINGWANHONG RUANGAO is applied on antiseptic gauze, mulching wound surface, antiseptic gauze wrapping, change dressings every day once, use three days continuously.
Diagnostic criteria:
Skin, after hydrothermal solution, steam, chemical drugs are scalded, is scalded face pain, redness, is got blister, and even injures muscle, skeleton, gray or bronzing.
Observation index: before and after observing treatment, which disease has change, symptom after treatment, sign disappears or alleviates.
Curative effect determinate standard: the variation which aspect and which degree have occurred before and after treatment just belongs to recovery from illness, effective, improvement.
Clinical recovery: clinical symptoms, sign disappear, it is normal that burn and scald face recovers.
Effective: clinical symptoms, sign disappear substantially, it is normal that burn and scald face recovers substantially.
Effective: clinical symptoms, sign make moderate progress, burn and scald face situation has certain improvement.
Invalid: clinical symptoms, sign are all without improving or increasing the weight of, and scald face is without improvement.
Result of the test is as follows:
Figure BDA0000481017180000141
Efficacy evaluation: in the clinical trial of burn and scald, the external medicinal liquid that patient's external is made by the Chinese medicine composition for the treatment of burn and scald of the present invention, effective percentage 100%, cure rate 60%; And matched group external JINGWANHONG RUANGAO, effective percentage 80%, cure rate 36.7%.The effect for the treatment of group and matched group relatively shows, treated effect and the cure rate of the external medicinal liquid being made by the Chinese medicine composition for the treatment of burn and scald of the present invention to burn and scald is higher, have more rate to reach 100%, and treatment cycle is short.
Model case 1:
Appoint certain, man, 45 years old, right lower limb burn 9 days, the dark trace that burns of burn surface.Treatment: give the external medicinal liquid that debridement and external are made by the Chinese medicine composition for the treatment of burn and scald of the present invention, every 8-10min smears once, smears continuously two hours.Medicinal liquid stops 20 days at burn surface.After burn surface incrustation, there will be blood plasma, then with 706 plasma substitute transfusions, until burn surface recovery from illness.During treatment, forbid edible Rhizoma Zingiberis Recens, raw Bulbus Allii, also forbid edible Herba Coriandri, Fructus Capsici (Herba Coriandri, raw ripe all the banning use of of Fructus Capsici).From photo Fig. 1, Fig. 2 before treating and after treatment, after treatment, burn surface skin red and swollen, that have burning trace recovers normal respectively.
Model case 2:
Lee, female, 3 years old, right arm boiled water was scalded, wound surface suppurative infection.Treatment: give the external medicinal liquid that debridement and external are made by the Chinese medicine composition for the treatment of burn and scald of the present invention, every 8-10min smears once, smears continuously two hours.Medicinal liquid stops 5 days at scald face.After 5 days, the incrustation of scald face, scalds suppuration, the infection of face and is controlled.During treatment, forbid edible Rhizoma Zingiberis Recens, raw Bulbus Allii, also forbid edible Herba Coriandri, Fructus Capsici (Herba Coriandri, raw ripe all the banning use of of Fructus Capsici).From photo Fig. 3, Fig. 4 before treating and after treatment, after treatment, the scald face that infection suppurates fails to form a scab is always formed a scab respectively, and part crust comes off naturally.

Claims (10)

1. treat the Chinese medicine composition of burn and scald for one kind, it is characterized in that, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50.
2. the Chinese medicine composition for the treatment of burn and scald according to claim 1, it is characterized in that, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 30-40, Radix Polygalae 30-40, Radix Angelicae Sinensis 30-40, Herba Schizonepetae 20-30, charred Radix Sanguisorbae 20-40, Fructus Cnidii 20-40, Radix Codonopsis 20-40, Radix Paeoniae Alba 20-40, Poria 20-40, Herba speranskiae tuberculatae 20-40, Fructus Lycii 20-40, Cortex Lycii 20-40, Rhizoma Gastrodiae 20-40, Pericarpium Citri Reticulatae 20-40, Semen Momordicae 30-40, black Serpentis 30-40.
3. the Chinese medicine composition for the treatment of burn and scald according to claim 2, it is characterized in that, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 35, Radix Polygalae 35, Radix Angelicae Sinensis 35, Herba Schizonepetae 25, charred Radix Sanguisorbae 30, Fructus Cnidii 30, Radix Codonopsis 30, Radix Paeoniae Alba 30, Poria 30, Herba speranskiae tuberculatae 30, Fructus Lycii 30, Cortex Lycii 30, Rhizoma Gastrodiae 30, Pericarpium Citri Reticulatae 30, Semen Momordicae 35, black Serpentis 35.
4. the external medicinal liquid being made by the Chinese medicine composition of the treatment burn and scald described in claim 1~3 any one, is characterized in that, described external medicinal liquid comprises the composition of following weight portion:
Figure FDA0000481017170000011
5. external medicinal liquid according to claim 4, is characterized in that, described Chinese liquor is 40-70 degree, and described external medicinal liquid also comprises that parts by weight are the glycerol of 2-6.
6. external medicinal liquid according to claim 5, is characterized in that, described external medicinal liquid comprises the composition of following weight portion:
Figure FDA0000481017170000021
7. according to the preparation method of the Chinese medicine composition described in claim 1~3 any one, it is characterized in that,
Described method comprises the steps:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 30-55 DEG C decocts 3-6h, merges three times decocting liquid, filters to get filtrate; 40-50 DEG C of concentrated described filtrate, concentrated 0.5-1.5h obtains the extractum that relative density is 1.20-1.25; The ethanol that adds 90%-95% carries out precipitate with ethanol, reclaims ethanol concentrated, dry at 45-50 DEG C, makes fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol that 6-10 doubly measures 90%-95%, 40-60 DEG C of reflux, extract, 3-4h, reclaim ethanol concentrated, dry at 40-50 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
8. the preparation method of Chinese medicine composition according to claim 7, is characterized in that,
Described method comprises the steps:
A) Radix Polygalae, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, the Herba speranskiae tuberculatae of described components by weight percent ratio are decocted with water three times, each amount of water is not have medicine to be advisable, and 40 DEG C decoct 4h, merge three times decocting liquid, filter to get filtrate; 45 DEG C of concentrated described filtrates, concentrated 1h obtains the extractum that relative density is 1.20-1.25; Add 95% ethanol and carry out precipitate with ethanol, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added to ethanol and carry out reflux, extract, three times, add for the first time the ethanol of 8 times of amounts 95%, 50 DEG C of reflux, extract, 3.5h, reclaim ethanol concentrated, dry at 45 DEG C, make fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
9. the preparation method of external medicinal liquid according to claim 4, is characterized in that, described method comprises the steps:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) to the Chinese liquor that adds described weight portion in described Chinese medicine composition, stir, obtain Chinese medicine composition solution;
C) to the potassium sorbate and the L MALIC ACID that add described weight portion in described Chinese medicine composition solution, stir, and room temperature places 2-5 days, must treat the external medicinal liquid of burn and scald;
D) the external medicinal liquid sterilizing, the bottling that step c) are obtained.
10. according to the preparation method of the external medicinal liquid described in claim 5,6 any one, it is characterized in that, described method comprises the steps:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) to the Chinese liquor that adds described weight portion in described Chinese medicine composition, stir, obtain Chinese medicine composition solution 1;
C) to the glycerol that adds described weight portion in described Chinese medicine composition solution 1, stir, obtain Chinese medicine composition solution 2;
D) to the potassium sorbate and the L MALIC ACID that add described weight portion in described Chinese medicine composition solution 2, stir, and room temperature places 3 days, must treat the external medicinal liquid of burn and scald;
E) the external medicinal liquid sterilizing, the bottling that step d) are obtained.
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CN105663783A (en) * 2016-01-18 2016-06-15 四川千力原生农业股份有限公司 Chinese herbal medicinal liquor for treating scald and burn as well as preparation method

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* Cited by examiner, † Cited by third party
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CN105232818A (en) * 2015-11-09 2016-01-13 魏玉平 Traditional Chinese medicine composition for nursing and washing burns and scalds
CN105663783A (en) * 2016-01-18 2016-06-15 四川千力原生农业股份有限公司 Chinese herbal medicinal liquor for treating scald and burn as well as preparation method

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