CN103830593B - A kind of Chinese medicine composition and external medicinal liquid thereof for the treatment of burn and scald - Google Patents
A kind of Chinese medicine composition and external medicinal liquid thereof for the treatment of burn and scald Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition and external medicinal liquid thereof for the treatment of burn and scald, the Chinese medicine composition of this treatment burn and scald mainly obtains with the raw material that following weight portion forms: Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50.The invention provides a kind of Chinese medicine composition and external medicinal liquid thereof for the treatment of burn and scald, non-stimulated, have no side effect, degree of safety is high, allergic phenomena can not occur, effectively can treat burn and scald, skin need not be taken off in therapeutic process, there is no pain, not need skin-grafting, preventing from scar, efficient recovery injury skin can be had to former state, effective percentage 100%, cure rate 60%.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine composition of the treatment burn and scald prepared with pure plant material and external medicinal liquid thereof.
Technical background
In daily life, the skin burn that accidentally causes because taking action or scald often can occur, the lighter's pain is rubescent, severe one is bubbled, and even exfoliation is downright bad, hinders to bone.As cured not in time, pathogenic factor and antibacterial invade, and not only can expand wound surface, skin ulceration, even cause infection, produce septicemia, cause death.The medicine that current treatment is scalded is a lot, but slow, the weak effect of generally taking effect, can not normal healing, even infection suppurates, scar.Chinese patent CN101721535A discloses a kind of preparation and application for the treatment of burn and scald medicine for external use, with Radix Sanguisorbae, the Radix Angelicae Dahuricae, white Adeps Serpentis, powder, fresh ground Indigo Naturalis, Radix Codonopsis, ground beetle, Squama Manis, Herba Saussureae Involueratae and Ovum Gallus domesticus album for major ingredient; Be equipped with Rhizoma Coptidis, Radix Ophiopogonis pain, dog oil, Radix Rehmanniae, Radix Angelicae Sinensis, Flos Carthami, Radix Et Rhizoma Rhei, Borneolum Syntheticum, process, serve the medical effect of heat clearing away, removing toxic substances, antiinflammatory, the muscle that heals, grows, but it is raw materials used more, preparation method is loaded down with trivial details, can not pain be avoided in therapeutic process, effectively can not avoid cicatrix, recover injury skin.
Summary of the invention
The object of this invention is to provide one and effectively can treat burn and scald, skin in therapeutic process, need not be taken off, there is no pain, do not need skin-grafting, preventing from scar, efficient recovery injury skin can be had to the Chinese medicine composition of former state.
Another object of the present invention is to provide by the obtained external medicinal liquid of the Chinese medicine composition of this treatment burn and scald.
The Chinese medicine composition for the treatment of burn and scald of the present invention, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50.
The Chinese medicine composition for the treatment of burn and scald of the present invention, not only can treat burn and scald, can also treat the dermatosis such as herpes.
The Chinese medicine composition for the treatment of burn and scald of the present invention, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 30-40, Radix Polygalae 30-40, Radix Angelicae Sinensis 30-40, Herba Schizonepetae 20-30, charred Radix Sanguisorbae 20-40, Fructus Cnidii 20-40, Radix Codonopsis 20-40, Radix Paeoniae Alba 20-40, Poria 20-40, Herba speranskiae tuberculatae 20-40, Fructus Lycii 20-40, Cortex Lycii 20-40, Rhizoma Gastrodiae 20-40, Pericarpium Citri Reticulatae 20-40, Semen Momordicae 30-40, black Serpentis 30-40.
The Chinese medicine composition for the treatment of burn and scald of the present invention, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 35, Radix Polygalae 35, Radix Angelicae Sinensis 35, Herba Schizonepetae 25, charred Radix Sanguisorbae 30, Fructus Cnidii 30, Radix Codonopsis 30, Radix Paeoniae Alba 30, Poria 30, Herba speranskiae tuberculatae 30, Fructus Lycii 30, Cortex Lycii 30, Rhizoma Gastrodiae 30, Pericarpium Citri Reticulatae 30, Semen Momordicae 35, black Serpentis 35.
Described Chinese medicine composition can make medicine for external use, also can make oral medicine.
Patient, in the process using the dermatosis such as described traditional Chinese medicine composition for treating burn and scald, forbids edible Rhizoma Zingiberis Recens, raw Bulbus Allii, also forbids edible Herba Coriandri, Fructus Capsici (ripe all the prohibitting the use of Herba Coriandri, Fructus Capsici life).
The external medicinal liquid that the Chinese medicine composition for the treatment of burn and scald of the present invention is obtained, described external medicinal liquid comprises the composition of following weight portion:
The external medicinal liquid obtained by the Chinese medicine composition for the treatment of burn and scald of the present invention, in treatment burn and scald process, the wounded does not have pain, does not need skin-grafting, preventing from scar, can have efficient recovery injury skin to former state.
External medicinal liquid of the present invention, described Chinese liquor is 40-70 degree, and described external medicinal liquid also comprises the glycerol that parts by weight are 2-6.
The Chinese liquor of 40-70 degree effectively can ensure the therapeutic effect of external medicinal liquid, again can effective sterilizing, avoids burn and scald face to infect.
Adding of glycerol, can ensure, in the process of smearing external medicinal liquid treatment burn and scald, can therapeutic effect be ensured, the dry and cracked of burn and scald injury skin can be avoided again, keep moistening, strengthen therapeutic effect.
External medicinal liquid of the present invention, described external medicinal liquid comprises the composition of following weight portion:
The preparation method of Chinese medicine composition of the present invention, comprises the steps:
A) Radix Polygalae of described components by weight percent ratio, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, Herba speranskiae tuberculatae are decocted with water three times, each amount of water was advisable not have medicine, and 30-55 DEG C decocts 3-6h, merge three decocting liquids, filter to get filtrate; 40-50 DEG C of concentrated described filtrate, concentrated 0.5-1.5h obtains the extractum that relative density is 1.20-1.25; The ethanol adding 90%-95% carries out precipitate with ethanol, reclaims ethanol and concentrates, dry at 45-50 DEG C, obtained fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added ethanol and carry out reflux, extract, three times, add the ethanol of 6-10 times amount 90%-95% for the first time, 40-60 DEG C of reflux, extract, 3-4h, reclaim ethanol and concentrate, dry at 40-50 DEG C, obtained fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
The preparation method of Chinese medicine composition of the present invention, principle is simple, easy to operate.
The preparation method of Chinese medicine composition of the present invention, comprises the steps:
A) Radix Polygalae of described components by weight percent ratio, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, Herba speranskiae tuberculatae are decocted with water three times, each amount of water was advisable not have medicine, and 40 DEG C decoct 4h, merge three decocting liquids, filter to get filtrate; 45 DEG C of concentrated described filtrates, concentrated 1h obtains the extractum that relative density is 1.20-1.25; The ethanol adding 95% carries out precipitate with ethanol, reclaims ethanol and concentrates, dry at 45 DEG C, obtained fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added ethanol and carry out reflux, extract, three times, add the ethanol of 8 times amount 95% for the first time, 50 DEG C of reflux, extract, 3.5h, reclaim ethanol and concentrate, dry at 45 DEG C, obtained fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
The preparation method of external medicinal liquid of the present invention, comprises the steps:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) in described Chinese medicine composition, add the Chinese liquor of 10-20 times amount, stir, obtain Chinese medicine composition solution;
C) in described Chinese medicine composition solution, add potassium sorbate and the L MALIC ACID of described weight portion, stir, and room temperature places 2-5 days, must treat the external medicinal liquid of burn and scald;
D) external medicinal liquid sterilizing step c) obtained, bottling.
The preparation method of external medicinal liquid of the present invention, principle is simple, easy to operate.
The preparation method of external medicinal liquid of the present invention, comprises the steps:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) in described Chinese medicine composition, add the Chinese liquor of 15 times amount, stir, obtain Chinese medicine composition solution 1;
C) in described Chinese medicine composition solution 1, add the glycerol of described weight portion, stir, obtain Chinese medicine composition solution 2;
D) in described Chinese medicine composition solution 2, add potassium sorbate and the L MALIC ACID of described weight portion, stir, and room temperature places 3 days, the external medicinal liquid of burn and scald must be treated;
E) external medicinal liquid sterilizing step d) obtained, bottling.
During external external medicinal liquid of the present invention, at will can not touch wound, a small amount of medicinal liquid can be injected by needle tubing, only need once, as the wounded has touched the bubble in the condition of the injury, also do not take off skin, directly added medicine to.
External medicinal liquid of the present invention, can also prepare in accordance with the following methods:
Ratio of component takes each raw material (Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50) by weight, and be immersed in the Chinese liquor of 40-70 degree of 5-10 times amount, shady place preserves 15 days, to obtain final product.
Source raw materials used in the present invention is as follows:
Borneolum Syntheticum (Dipterocarpaceae): the resin of Spore density Borneolum Syntheticum and volatile oil processed goods extract the crystallization obtained.Acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has refreshment of having one's ideas straightened out, and the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, and heat-damp in summer hoodwinks key clearly, and sore throat is deaf, and aphtha tooth swells, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Radix Polygalae (PolygalatenuifoliaWilld.): Polygalaceae rogation flower dicotyledon.Warm in nature, bitter in the mouth, pungent, the function of there is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling, for heart kidney not .. hand over the insomnia and dreamful sleep caused, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
The dry root that Radix Angelicae Sinensis (Angelicasinensis) is umbelliferae angelica.Sweet in the mouth, pungent, bitter, warm in nature; Return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation; Cure mainly: all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Herba Schizonepetae (NepetacatariaL.): Labiatae, Nepeta.Taste is put down, and warm in nature, nontoxic, faint scent is dense; Enter lung, Liver Channel.Expelling pathogenic wind from the body surface, declares malicious rash, treating blood disorders relieving convulsion; Cure mainly flu cold and heat, headache, eye itching, pharyngalgia, cough, measles, rubella, carbuncle skin ulcer, spit blood, clot blood, has blood in stool, metrorrhagia, postpartum apoplexy, bruise.
Charred Radix Sanguisorbae: the root of Rosaceae herbaceos perennial Radix Sanguisorbae SanguisorbaofficinalisL..Bitter, sour, cool; Return liver, stomach, large intestine channel.Cooling blood for hemostasis, removing toxic substances sore.The various hemorrhage and burn due to hot liquid or fire for the treatment of heat in blood etc.Clinical many parch to black are used as medicine.
Fructus Cnidii (Cnidiummonnieri(L.) Cuss.): the dry mature fruit of samphire cnidium monnieri.Warm in nature, acrid in the mouth, hardship.Warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Radix Codonopsis (Codonopsispilosula (Franch.) Nannf.): campanulaceae Codonopsis plant Radix Codonopsis, element spend the dry root of Radix Codonopsis or radix codonpsis tangshen.Property is put down, sweet in the mouth, micro-acid; Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Radix Paeoniae Alba (PaeonialactifloraPall.): another name, the Radix Paeoniae Alba, Radix Paeoniae, Ranunculaceae, Paeonia herbaceos perennial.Cold nature, bitter in the mouth, acid; Return liver, spleen channel.Nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing the hyperactive liver sun.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For have a headache dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Poria (PoriacocosWolf): the sclerotium of On Polyporaceae Poria.Property flat, sweet in the mouth, light; Enter the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.
Herba speranskiae tuberculatae (GardenBalsamStem): Phrymaceae Herba speranskiae tuberculatae platymiscium.Acrid in the mouth, warm in nature; Enter Liver Channel.Expelling wind and removing dampness, promoting blood circulation and detumescence pain relieving.For rheumatic arthralgia, muscles contracture, traumatic injury, sore swollen toxin.
Fructus Lycii (FRUCTUSLYCII): the multi-branched shrub plant of Solanaceae Lycium.Sweet in the mouth, property are flat; Return liver, kidney, lung meridian.Nourishing YIN and supplementing blood, replenishing vital essence to improve eyesight.Cure mainly: asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Cortex Lycii (CortexLycii): the root bark of Solanaceae, Lycium Fructus Lycii (LyciumchinenseMill.).Cold in nature, sweet in the mouth.Removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.
Rhizoma Gastrodiae (GastrodiaelataBl.): the orchid family, Gastrodia herbaceos perennial.Suppressing the hyperactive liver to relieve the wind syndrome, wind-expelling pain-stopping.Have a dizzy spell in order to treatment, the disease such as numb limbs and tense tendons, infantile convulsion.
Pericarpium Citri Reticulatae: the mature peel of rutaceae orange and variety thereof.Bitter in the mouth, pungent, warm in nature; Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Semen Momordicae (Momordicacochinchinensis (Lour.) Spreng.): Cucurbitaceae Fructus Momordicae charantiae book plant.Bitter, micro-sweet, cool in nature, poisonous; Return liver, spleen, stomach warp.Mass dissipating and swelling eliminating, counteracting toxic substances treats skin ulcer.For sore swollen toxin, acute mastitis, scrofula, anal fistula, chronic eczema, tinea alba.
Black Serpentis (Zoacysdhumnades): release name, Zaocys, Zaocys.The live body of Chordata Colubridae animal Zaocys.Property sweet, flat, return Liver Channel, nontoxic.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Beneficial effect of the present invention is:
(1) raw material is adopted mostly to be the high pure plant of degree of safety or pure plant extracts, the Chinese medicine composition for the treatment of burn and scald of preparation is non-stimulated, have no side effect, degree of safety is high, allergic phenomena can not occur, effectively can treat burn and scald, need not take off skin, not have pain, not need skin-grafting, preventing from scar, can have efficient recovery injury skin to the Chinese medicine composition of former state in therapeutic process.
(2) Chinese medicine composition for the treatment of burn and scald of the present invention, preparation method is simple, easy to operate.
Accompanying drawing explanation
Fig. 1 is that the right lower limb before appointing certain treatment in model case 1 scalds face photo;
Fig. 2 is that the right lower limb after appointing certain treatment in model case 1 scalds face photo;
Fig. 3 is that the right arm in model case 2 before Lee's treatment scalds face photo;
Fig. 4 is that the right arm in model case 2 after Lee's treatment scalds face photo.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1 Chinese medicine composition
Prescription:
Borneolum Syntheticum 20g, Radix Polygalae 20g, Radix Angelicae Sinensis 20g, Herba Schizonepetae 10g, charred Radix Sanguisorbae 15g, Fructus Cnidii 15g, Radix Codonopsis 15g, Radix Paeoniae Alba 15g, Poria 10g, Herba speranskiae tuberculatae 10g, Fructus Lycii 10g, Cortex Lycii 10g, Rhizoma Gastrodiae 10g, Pericarpium Citri Reticulatae 10g, Semen Momordicae 20g, black Serpentis 20g.
Method for making:
A) Radix Polygalae of described components by weight percent ratio, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, Herba speranskiae tuberculatae are decocted with water three times, each amount of water was advisable not have medicine, and 30 DEG C decoct 6h, merge three decocting liquids, filter to get filtrate; 40 DEG C of concentrated described filtrates, concentrated 1.5h obtains the extractum that relative density is 1.20; The ethanol adding 90%% carries out precipitate with ethanol, reclaims ethanol and concentrates, dry at 45 DEG C, obtained fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added ethanol and carry out reflux, extract, three times, add the ethanol of 6 times amount 90%% for the first time, 40 DEG C of reflux, extract, 3h, reclaim ethanol and concentrate, dry at 40 DEG C, obtained fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
Embodiment 2 Chinese medicine composition
Prescription:
Borneolum Syntheticum 50g, Radix Polygalae 50g, Radix Angelicae Sinensis 50g, Herba Schizonepetae 40g, charred Radix Sanguisorbae 50g, Fructus Cnidii 45g, Radix Codonopsis 45g, Radix Paeoniae Alba 45g, Poria 50g, Herba speranskiae tuberculatae 50g, Fructus Lycii 50g, Cortex Lycii 50g, Rhizoma Gastrodiae 50g, Pericarpium Citri Reticulatae 50g, Semen Momordicae 50g, black Serpentis 50g.
Method for making:
A) Radix Polygalae of described components by weight percent ratio, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, Herba speranskiae tuberculatae are decocted with water three times, each amount of water was advisable not have medicine, and 55 DEG C decoct 3h, merge three decocting liquids, filter to get filtrate; 50 DEG C of concentrated described filtrates, concentrated 0.5h obtains the extractum that relative density is 1.25; The ethanol adding 95% carries out precipitate with ethanol, reclaims ethanol and concentrates, dry at 50 DEG C, obtained fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added ethanol and carry out reflux, extract, three times, add the ethanol of 10 times amount 95% for the first time, 60 DEG C of reflux, extract, 4h, reclaim ethanol and concentrate, dry at 50 DEG C, obtained fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
Embodiment 3 Chinese medicine composition
Prescription:
Borneolum Syntheticum 30g, Radix Polygalae 30g, Radix Angelicae Sinensis 30g, Herba Schizonepetae 20g, charred Radix Sanguisorbae 20g, Fructus Cnidii 20g, Radix Codonopsis 20g, Radix Paeoniae Alba 20g, Poria 20g, Herba speranskiae tuberculatae 20g, Fructus Lycii 20g, Cortex Lycii 20g, Rhizoma Gastrodiae 20g, Pericarpium Citri Reticulatae 20g, Semen Momordicae 30g, black Serpentis 30g.
Method for making: obtain Chinese medicine composition according to the preparation method of embodiment 1.
Embodiment 4 Chinese medicine composition
Prescription:
Borneolum Syntheticum 40g, Radix Polygalae 40g, Radix Angelicae Sinensis 40g, Herba Schizonepetae 30g, charred Radix Sanguisorbae 40g, Fructus Cnidii 40g, Radix Codonopsis 40g, Radix Paeoniae Alba 40g, Poria 40g, Herba speranskiae tuberculatae 40g, Fructus Lycii 40g, Cortex Lycii 40g, Rhizoma Gastrodiae 40g, Pericarpium Citri Reticulatae 40g, Semen Momordicae 40g, black Serpentis 40g.
Method for making: obtain Chinese medicine composition according to the preparation method of embodiment 2.
Embodiment 5 Chinese medicine composition
Prescription:
Borneolum Syntheticum 35g, Radix Polygalae 35g, Radix Angelicae Sinensis 35g, Herba Schizonepetae 25g, charred Radix Sanguisorbae 30g, Fructus Cnidii 30g, Radix Codonopsis 30g, Radix Paeoniae Alba 30g, Poria 30g, Herba speranskiae tuberculatae 30g, Fructus Lycii 30g, Cortex Lycii 30g, Rhizoma Gastrodiae 30g, Pericarpium Citri Reticulatae 30g, Semen Momordicae 35g, black Serpentis 35g.
Method for making:
A) Radix Polygalae of described components by weight percent ratio, Radix Angelicae Sinensis, Herba Schizonepetae, charred Radix Sanguisorbae, Radix Codonopsis, Poria, Herba speranskiae tuberculatae are decocted with water three times, each amount of water was advisable not have medicine, and 40 DEG C decoct 4h, merge three decocting liquids, filter to get filtrate; 45 DEG C of concentrated described filtrates, concentrated 1h obtains the extractum that relative density is 1.20; The ethanol adding 95% carries out precipitate with ethanol, reclaims ethanol and concentrates, dry at 45 DEG C, obtained fine powder 1;
B) Borneolum Syntheticum of described components by weight percent ratio, Fructus Cnidii, Radix Paeoniae Alba, Poria, Herba speranskiae tuberculatae, Fructus Lycii, Cortex Lycii, Rhizoma Gastrodiae, Pericarpium Citri Reticulatae, Semen Momordicae, black Serpentis are added ethanol and carry out reflux, extract, three times, add the ethanol of 8 times amount 95% for the first time, 50 DEG C of reflux, extract, 3.5h, reclaim ethanol and concentrate, dry at 45 DEG C, obtained fine powder 2;
C) then fine powder 1 and fine powder 2 are mixed, obtain Chinese medicine composition.
Embodiment 6 external medicinal liquid
Prescription:
Method for making:
A) first by Chinese medicine composition, 40 degree of Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) in described Chinese medicine composition, add the Chinese liquor of described weight portion, stir, obtain Chinese medicine composition solution;
C) in described Chinese medicine composition solution, add potassium sorbate and the L MALIC ACID of described weight portion, stir, and room temperature places 5 days, the external medicinal liquid of burn and scald must be treated;
D) external medicinal liquid sterilizing step c) obtained, bottling.
Embodiment 7 external medicinal liquid
Prescription:
Method for making: the external medicinal liquid obtaining treatment burn and scald according to the method for embodiment 6.
Embodiment 8 external medicinal liquid
Prescription:
Method for making:
A) first by Chinese medicine composition, Chinese liquor and each adjuvant by weight ratio of component weigh, for subsequent use;
B) in described Chinese medicine composition, add 70 degree of Chinese liquor of described weight portion, stir, obtain Chinese medicine composition solution 1;
C) in described Chinese medicine composition solution 1, add the glycerol of described weight portion, stir, obtain Chinese medicine composition solution 2;
D) in described Chinese medicine composition solution 2, add potassium sorbate and the L MALIC ACID of described weight portion, stir, and room temperature places 3 days, the external medicinal liquid of burn and scald must be treated;
E) external medicinal liquid sterilizing step d) obtained, bottling.
Embodiment 9 external medicinal liquid
Prescription:
Method for making: obtain external medicinal liquid according to the method for embodiment 8.
Embodiment 10 external medicinal liquid
Prescription:
Method for making: obtain external medicinal liquid according to the method for embodiment 8.
For this situation is described, now further illustrate effect of the present invention by test example as follows:
Test example 1
Treatment group 30 example, 3 ~ 60 years old age, average 20 years old, the course of disease 1 ~ 3 month.
Take mode: treatment group: the external medicinal liquid that external is obtained by the Chinese medicine composition for the treatment of burn and scald of the present invention, first use normal saline flushing, the secretions in cleaning ulcer and burn and scald face, the external medicinal liquid of embodiment 10 is dipped by swab stick, be applied on the burn and scald face after cleaning, every 8-10min smears once, smears two hours continuously.Matched group: external JINGWANHONG RUANGAO (composition: Radix Sanguisorbae, Radix Rehmanniae, Pericarpium Papaveris, Radix Angelicae Sinensis, Semen Persicae, Rhizoma Coptidis, Semen Momordicae, Crinis Carbonisatus, Petiolus Trachycarpi, Herba Lobeliae Chinensis, Eupolyphaga Seu Steleophaga, Radix Ampelopsis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Flos Lonicerae, Flos Carthami, Radix Et Rhizoma Rhei, Radix Sophorae Flavescentis, Galla Chinensis, the Flos Sophorae Immaturus, Fructus Chaenomelis, Rhizoma Atractylodis, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Scutellariae, Rhizoma Picrorhizae, Rhizoma Chuanxiong, Fructus Gardeniae, Fructus Mume, Borneolum Syntheticum, Sanguis Draxonis), wound surface is cleared up with normal saline, apply JINGWANHONG RUANGAO or JINGWANHONG RUANGAO is applied on antiseptic gauze, mulching wound surface, antiseptic gauze is wrapped up, change dressings every day once, continuous use three days.
Diagnostic criteria:
Skin, after hydrothermal solution, steam, chemical drugs are scalded, is scalded face pain, redness, is got blister, even injure muscle, skeleton, gray or bronzing.
Observation index: before and after observing treatment, which disease has change, symptom after treatment, sign disappears or alleviates.
Curative effect determinate standard: the change that there occurs which aspect and which degree before and after treatment just belongs to recovery from illness, effectively, takes a turn for the better.
Clinical recovery: clinical symptoms, sign disappear, burn and scald face recovers normal.
Effective: clinical symptoms, sign disappear substantially, burn and scald face recovers normal substantially.
Effective: clinical symptoms, sign make moderate progress, burn and scald face situation has certain improvement.
Invalid: clinical symptoms, sign are all without improving or increasing the weight of, and face of scalding is without improvement.
Result of the test is as follows:
Efficacy evaluation: in the clinical trial of burn and scald, the external medicinal liquid that patient's external is obtained by the Chinese medicine composition for the treatment of burn and scald of the present invention, effective percentage 100%, cure rate 60%; And matched group external JINGWANHONG RUANGAO, effective percentage 80%, cure rate 36.7%.The effectiveness comparison for the treatment of group and matched group shows, the external medicinal liquid obtained by the Chinese medicine composition for the treatment of burn and scald of the present invention to the treated effect of burn and scald and cure rate higher, have more rate to reach 100%, and treatment cycle is short.
Model case 1:
Appoint certain, man, 45 years old, right lower limb was burnt 9 days, and burn surface dark color burns trace.Treatment: give debridement and external by the obtained external medicinal liquid of the Chinese medicine composition for the treatment of burn and scald of the present invention, every 8-10min smears once, smears two hours continuously.Medicinal liquid stops 20 days at burn surface.After burn surface incrustation, there will be blood plasma, then with 706 plasma substitute transfusions, until burn surface recovery from illness.Treatments period, forbids edible Rhizoma Zingiberis Recens, raw Bulbus Allii, also forbids edible Herba Coriandri, Fructus Capsici (ripe all the prohibitting the use of Herba Coriandri, Fructus Capsici life).Respectively from photo Fig. 1, Fig. 2 for the treatment of after front and treatment, after treatment, burn surface skin recovery that is red and swollen, that have burning trace is normal.
Model case 2:
Lee, female, 3 years old, right arm boiled water was scalded, wound surface suppurative infection.Treatment: give debridement and external by the obtained external medicinal liquid of the Chinese medicine composition for the treatment of burn and scald of the present invention, every 8-10min smears once, smears two hours continuously.Medicinal liquid stops 5 days in scald face.After 5 days, scald face incrustation, scald the suppuration in face, infection is controlled.Treatments period, forbids edible Rhizoma Zingiberis Recens, raw Bulbus Allii, also forbids edible Herba Coriandri, Fructus Capsici (ripe all the prohibitting the use of Herba Coriandri, Fructus Capsici life).Respectively from photo Fig. 3, Fig. 4 for the treatment of after front and treatment, after treatment, form a scab in the scald face that infection suppurates fails to form a scab always, part crust comes off naturally.
Claims (8)
1. treat the Chinese medicine composition of burn and scald for one kind, it is characterized in that, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 20-50, Radix Polygalae 20-50, Radix Angelicae Sinensis 20-50, Herba Schizonepetae 10-40, charred Radix Sanguisorbae 15-50, Fructus Cnidii 15-45, Radix Codonopsis 15-45, Radix Paeoniae Alba 15-45, Poria 10-50, Herba speranskiae tuberculatae 10-50, Fructus Lycii 10-50, Cortex Lycii 10-50, Rhizoma Gastrodiae 10-50, Pericarpium Citri Reticulatae 10-50, Semen Momordicae 20-50, black Serpentis 20-50.
2. the Chinese medicine composition for the treatment of burn and scald according to claim 1, it is characterized in that, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 30-40, Radix Polygalae 30-40, Radix Angelicae Sinensis 30-40, Herba Schizonepetae 20-30, charred Radix Sanguisorbae 20-40, Fructus Cnidii 20-40, Radix Codonopsis 20-40, Radix Paeoniae Alba 20-40, Poria 20-40, Herba speranskiae tuberculatae 20-40, Fructus Lycii 20-40, Cortex Lycii 20-40, Rhizoma Gastrodiae 20-40, Pericarpium Citri Reticulatae 20-40, Semen Momordicae 30-40, black Serpentis 30-40.
3. the Chinese medicine composition for the treatment of burn and scald according to claim 2, it is characterized in that, described Chinese medicine composition is made up of the raw material of following weight portion: Borneolum Syntheticum 35, Radix Polygalae 35, Radix Angelicae Sinensis 35, Herba Schizonepetae 25, charred Radix Sanguisorbae 30, Fructus Cnidii 30, Radix Codonopsis 30, Radix Paeoniae Alba 30, Poria 30, Herba speranskiae tuberculatae 30, Fructus Lycii 30, Cortex Lycii 30, Rhizoma Gastrodiae 30, Pericarpium Citri Reticulatae 30, Semen Momordicae 35, black Serpentis 35.
4., by the external medicinal liquid that the Chinese medicine composition of the treatment burn and scald described in any one of claims 1 to 3 is obtained, it is characterized in that, described external medicinal liquid comprises the composition of following weight portion:
5. external medicinal liquid according to claim 4, is characterized in that, described Chinese liquor is 40-70 degree, and described external medicinal liquid also comprises the glycerol that parts by weight are 2-6.
6. external medicinal liquid according to claim 5, is characterized in that, described external medicinal liquid comprises the composition of following weight portion:
7. the preparation method of external medicinal liquid according to claim 4, is characterized in that, described method comprises the steps:
A) first Chinese medicine composition, Chinese liquor and each adjuvant are weighed by weight, for subsequent use;
B) in described Chinese medicine composition, add the Chinese liquor of described weight portion, stir, obtain Chinese medicine composition solution;
C) in described Chinese medicine composition solution, add potassium sorbate and the L MALIC ACID of described weight portion, stir, and room temperature places 2-5 days, must treat the external medicinal liquid of burn and scald;
D) by step c) the external medicinal liquid sterilizing that obtains, bottling.
8. the preparation method of the external medicinal liquid according to any one of claim 5,6, it is characterized in that, described method comprises the steps:
A) first Chinese medicine composition, Chinese liquor and each adjuvant are weighed by weight, for subsequent use;
B) in described Chinese medicine composition, add the Chinese liquor of described weight portion, stir, obtain Chinese medicine composition solution 1;
C) in described Chinese medicine composition solution 1, add the glycerol of described weight portion, stir, obtain Chinese medicine composition solution 2;
D) in described Chinese medicine composition solution 2, add potassium sorbate and the L MALIC ACID of described weight portion, stir, and room temperature places 3 days, the external medicinal liquid of burn and scald must be treated;
E) by steps d) the external medicinal liquid sterilizing that obtains, bottling.
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CN105232818A (en) * | 2015-11-09 | 2016-01-13 | 魏玉平 | Traditional Chinese medicine composition for nursing and washing burns and scalds |
CN105663783A (en) * | 2016-01-18 | 2016-06-15 | 四川千力原生农业股份有限公司 | Chinese herbal medicinal liquor for treating scald and burn as well as preparation method |
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CN101953952A (en) * | 2010-10-28 | 2011-01-26 | 张志献 | Powder for treating empyrosis |
CN103610833A (en) * | 2013-12-11 | 2014-03-05 | 齐岭山 | Unguent for treating burns and scalds |
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CN101953952A (en) * | 2010-10-28 | 2011-01-26 | 张志献 | Powder for treating empyrosis |
CN103610833A (en) * | 2013-12-11 | 2014-03-05 | 齐岭山 | Unguent for treating burns and scalds |
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