CN103768396B - A kind of medicine and preparation method being used for the treatment of hemoptysis of pulmonary tuberculosis - Google Patents
A kind of medicine and preparation method being used for the treatment of hemoptysis of pulmonary tuberculosis Download PDFInfo
- Publication number
- CN103768396B CN103768396B CN201410063000.6A CN201410063000A CN103768396B CN 103768396 B CN103768396 B CN 103768396B CN 201410063000 A CN201410063000 A CN 201410063000A CN 103768396 B CN103768396 B CN 103768396B
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- radix
- treatment
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention discloses a kind of medicine and the preparation method that are used for the treatment of hemoptysis of pulmonary tuberculosis, belong to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of: Herba potentillae fulgentis, Drymoglossum Herba Drymoglossi, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Bulbophylli inconspicui, Herba abutili indici, Auricularia, Cauliset Folium Piperis Hancei, Bulbophyllum peotinatum Pinet．, Shi Rong, Radix Malvae rotundifoliae, Radix didymospermatis caudati, Rhizoma alcasiae odorae, the Rhizoma Anemarrhenae, Caulis et Folium Crotalariae Assamicae, Flos Gomphrenae and Radix Xylosmae japonici; Choice of drug high-quality Chinese crude drug scientific compatibility of the present invention, there is effect of heat clearing and inflammation relieving, cooling blood for hemostasis, nourishing the lung to arrest cough, expelling wind and removing dampness, to the symptom such as cough, expectoration, spitting of blood, chest pain and uncomfortable in chest and dyspnea in various degree that treatment pulmonary tuberculosis causes, there is significant therapeutic effect, easy to carry, safe and reliable, without any side effects, with low cost, can arrive the object for the treatment of both the principal and secondary aspects of a disease, be a kind of ideal medicament being used for the treatment of hemoptysis of pulmonary tuberculosis.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and the preparation method that are used for the treatment of hemoptysis of pulmonary tuberculosis.
Background technology
Tuberculosis is the chronic infectious disease caused by mycobacterium tuberculosis, can invade and many internal organs, infects the most common with pulmonary Mycobacterium.Tulase belongs to Actinomycetal, the Mycobacterium of mycobacteriaceae, for there being the acid fast bacteria of pathogenicity, mainly divides for the types such as people, cattle, bird, Mus.Pathogenic person mainly human-like bacterium is had, the rare infection of cattle type bacterium to people.Tulase, to the drug resistance of medicine, can be developed by fastbacteria congenital in flora and be formed, the drug resistance that also comparatively fast can produce this medicine owing to being used alone a kind of antitubercular agent in human body, namely obtain fastbacteria.Fastbacteria can cause the difficulty in treatment, affects the treatment.Have closer tuberculosis contact history, onset can suddenly can be delayed, and mostly is low grade fever, night sweat, weak, poor appetite, becomes thin, female menstrual disorder etc.; Respiratory symptom has cough, expectoration, spitting of blood, chest pain, in various degree uncomfortable in chest or dyspnea.
Physical signs of lung is different and variant according to state of an illness weight, extent of disease, and tuberculosis in early days, among a small circle not easily finds positive sign, and the wider person's percussion of extent of disease be voiced sound, vocal fremitus enhancing, the low and moist rales of vesicular breathing sound.Late period, tuberculosis formed fibrosis, and local contraction makes pleura subside and mediastinal displacement.Have pleuritic rub in early days tuberculous pleuritis person, when forming a large amount of hydrothorax, thoracic wall is full, the turbid reality of percussion, and vocal fremitus and respiratory murmur lower or disappear.
At present, treatment hemoptysis of pulmonary tuberculosis is all generally that Western medicine or have an injection is treated, some Western medicine is mostly expensive, patient as go hospitalize the expense that spends also very high, and curative effect is slow, cure rate is low, after discontinuing medication, relapse rate is high, also has certain toxic and side effects to human body, so various big hospital is badly in need of a kind of short treating period, instant effect, and the medicine had no side effect.
Summary of the invention
The invention provides a kind of medicine and the preparation method that are used for the treatment of hemoptysis of pulmonary tuberculosis, choice of drug high-quality Chinese crude drug scientific compatibility of the present invention, there is effect of heat clearing and inflammation relieving, cooling blood for hemostasis, nourishing the lung to arrest cough, expelling wind and removing dampness, to the symptom such as cough, expectoration, spitting of blood, chest pain and uncomfortable in chest and dyspnea in various degree that treatment pulmonary tuberculosis causes, there is significant therapeutic effect, easy to carry, safe and reliable, without any side effects, with low cost, can arrive the object for the treatment of both the principal and secondary aspects of a disease, be a kind of ideal medicament being used for the treatment of hemoptysis of pulmonary tuberculosis.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine for hemoptysis of pulmonary tuberculosis, raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 58 ~ 84 parts of Drymoglossum Herba Drymoglossis 55 ~ 81 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 47 ~ 73 parts of Herba Bulbophylli inconspicui 42 ~ 69 parts
Herba abutili indici 42 ~ 68 parts of Auricularia 38 ~ 67 Fen Cauliset Folium Piperis Hancei 38 ~ 67 parts of Bulbophyllum peotinatum Pinet． 34 ~ 61 parts
Stone banyan 33 ~ 60 parts of Radix Malvae rotundifoliaes 28 ~ 57 parts of Radix didymospermatis caudati 26 ~ 56 portions of Rhizoma alcasiae odoraes 22 ~ 50 parts
The Rhizoma Anemarrhenae 21 ~ 47 parts of Caulis et Folium Crotalariae Assamicaes 18 ~ 44 parts of Flos Gomphrenaes 15 ~ 36 parts of Radix Xylosmae japonicis 13 ~ 32 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 62 ~ 80 parts of Drymoglossum Herba Drymoglossis 59 ~ 77 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 51 ~ 69 parts of Herba Bulbophylli inconspicui 47 ~ 65 parts
Herba abutili indici 46 ~ 64 parts of Auricularia 44 ~ 62 Fen Cauliset Folium Piperis Hancei 42 ~ 62 parts of Bulbophyllum peotinatum Pinet． 41 ~ 56 parts
Stone banyan 37 ~ 56 parts of Radix Malvae rotundifoliaes 32 ~ 52 parts of Radix didymospermatis caudati 31 ~ 51 portions of Rhizoma alcasiae odoraes 27 ~ 45 parts
The Rhizoma Anemarrhenae 25 ~ 43 parts of Caulis et Folium Crotalariae Assamicaes 22 ~ 40 parts of Flos Gomphrenaes 19 ~ 32 parts of Radix Xylosmae japonicis 17 ~ 29 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 67 ~ 75 parts of Drymoglossum Herba Drymoglossis 64 ~ 72 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 56 ~ 64 parts of Herba Bulbophylli inconspicui 52 ~ 60 parts
Herba abutili indici 51 ~ 59 parts of Auricularia 49 ~ 57 Fen Cauliset Folium Piperis Hancei 47 ~ 55 parts of Bulbophyllum peotinatum Pinet． 43 ~ 51 parts
Stone banyan 42 ~ 50 parts of Radix Malvae rotundifoliaes 37 ~ 47 parts of Radix didymospermatis caudati 36 ~ 46 portions of Rhizoma alcasiae odoraes 32 ~ 40 parts
The Rhizoma Anemarrhenae 30 ~ 38 parts of Caulis et Folium Crotalariae Assamicaes 27 ~ 35 parts of Flos Gomphrenaes 23 ~ 27 parts of Radix Xylosmae japonicis 21 ~ 25 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 71 parts of Drymoglossum Herba Drymoglossis 68 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 60 parts of Herba Bulbophylli inconspicui 56 parts
Herba abutili indici 55 parts of Auricularia 53 Fen Cauliset Folium Piperis Hancei 51 parts of Bulbophyllum peotinatum Pinet． 47 parts
Stone banyan 46 parts of Radix Malvae rotundifoliaes 42 parts of Radix didymospermatis caudati 41 portions of Rhizoma alcasiae odoraes 36 parts
The Rhizoma Anemarrhenae 34 parts of Caulis et Folium Crotalariae Assamicaes 31 parts of Flos Gomphrenaes 25 parts of Radix Xylosmae japonicis 23 parts.
Be used for the treatment of a preparation method for the medicine of hemoptysis of pulmonary tuberculosis, comprise following processing step:
(1) Herba potentillae fulgentis, Herba Bulbophylli inconspicui, Cauliset Folium Piperis Hancei and Shi Rong are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 7 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.11 ~ 1.13 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(2) Drymoglossum Herba Drymoglossi, Herba abutili indici, Auricularia, Bulbophyllum peotinatum Pinet．, Radix Malvae rotundifoliae, Radix didymospermatis caudati, Rhizoma alcasiae odorae, the Rhizoma Anemarrhenae and Flos Gomphrenae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.14 ~ 1.17, for subsequent use;
(3) Angiopteris magna Ching (Angiopteris majuscula Ching) and Caulis et Folium Crotalariae Assamicae are put into container, carry out pulverization process, grind into powder, cross 200 order fine powders, for subsequent use;
(4) by Radix Xylosmae japonici decontamination, section, dries, is placed in container, mixes well with wine, puts in pot to fry with slow fire to exhaust and micro-dry to wine, takes out, dries, be placed in mortar, grind into powder, cross 180 order fine powders for subsequent use;
(5) by the thick paste obtained by above-mentioned steps (1) ~ (4) and fine powder mixing, make capsule, obtain a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba potentillae fulgentis: bitter in the mouth, puckery, cold in nature; Return spleen, large intestine channel.Heat clearing and inflammation relieving, cooling blood for hemostasis.Control dysentery, enteritis, stomachache, hemoptysis of pulmonary tuberculosis, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, furuncle." choosing of Yunnan Chinese herbal medicine " carries: " cooling blood for hemostasis, astringing to arrest diarrhea.Control hemoptysis of pulmonary tuberculosis, spit blood, epistaxis, dyspepsia, anemia, dysentery.”
Drymoglossum Herba Drymoglossi: sweet in the mouth, light, slightly cool in nature; Return liver, lung meridian.Clearing away heat-damp and promoting diuresis, removing toxic substances parasite killing.To harness the Yellow River subcutaneous ulcer, rheumatalgia, parotitis, tuberculous lymphadenitis, mange, traumatic injury.Guangzhou air force " conventional Chinese herbal medicine handbook " carries: " eliminating inflammation and expelling toxin, dispelling wind stopping cough.To harness the Yellow River subcutaneous ulcer, tuberculous lymphadenitis, parotitis, cough hemoptysis, rheumatic ostalgia, breast carcinoma, constipation due to dry stool.”
Angiopteris magna Ching (Angiopteris majuscula Ching): bitter in the mouth, puckery, cold in nature; GUIXIN, lung, large intestine channel.Heat-clearing and toxic substances removing, hemostasis, damp eliminating diuresis.Cure mainly enteritis, dysentery, dyspepsia abdominal distention.Oedema due to nephritis, pulmonary tuberculosis, hemoptysis, metrorrhagia, traumatic injury, rheumatism, gastric and duodenal ulcers.
Herba Bulbophylli inconspicui: sweet in the mouth, light, cool in nature; Enter lung, stomach two warp.Nourishing YIN and clearing away heat, preventing phlegm from forming and stopping coughing.For xeropulmonary cough, hemoptysis of pulmonary tuberculosis, calentura excessive thirst, tonsillitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " moistening the lung and resolving phlegm, tonifying-Yin and nourishing-stomach.Control pulmonary tuberculosis cough, spitting of blood, cough due to chronic tracheitis, pneumonia convalescent period, chronic pharyngalgia, chronic gastritis, achlorhydria, inappetence, seminal emission.”
Herba abutili indici: sweet in the mouth, light, property is put down.Wind and heat dispersing, QI invigorating is sensible, diuresis of eliminating the phlegm.For flu, heat of a specified duration is not moved back, mumps, tinnitus, deaf, pulmonary tuberculosis, dysuria.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " wind and heat dispersing, ascending the clear and descending the turbid.Cure cold hyperpyrexia, mumps, deaf, tinnitus, first shape abscess, seminal emission.”
Auricularia: sweet in the mouth, property is put down.Fill blood, lung moistening is stopped blooding.For Qi and blood deficiency, extremity are twitched, cough due to deficiency of the lung, spitting of blood, spit blood, epistaxis, metrorrhagia, hypertension, constipation.Modern medicine confirms, the colloid in Auricularia can excrete after the impurity remained in digestive tract, waste adsorbent, has significant curative effect for calculus patient and cardiovascular and cerebrovascular vessel.
Cauliset Folium Piperis Hancei: acrid in the mouth, warm in nature; Return lung, spleen channel.Expelling wind and removing dampness, promoting blood circulation and detumescence, promoting the circulation of QI to relieve pain, preventing phlegm from forming and stopping coughing.Main air pain of dampness syndrome, stomachache, dysmenorrhea, traumatic injury, wind and cold cough with asthma, colicky." the practical Chinese herbal medicine in Guangxi newly selects " carries: " reducing swelling and alleviating pain, wind dispelling is trembled with fear, and stimulates the menstrual flow.Control traumatic injury, venom.”
Bulbophyllum peotinatum Pinet．: sweet in the mouth, hardship, light, cool in nature; Enter lung, liver two warp.YIN nourishing clearing away lung-heat, controls pulmonary tuberculosis hemoptysis.Nourishing the lung to arrest cough, silt releasing and analgesia.For pulmonary tuberculosis cough, cough with asthma QI rising in reverse order person, for the traumatic injury person of swelling and ache, containing ring Pseudobulbus Pholidotae Chinensis terpene alcohol, ring Pseudobulbus Pholidotae Chinensis terpene ketone.Modern medicine study confirms, the aqueous extract of Bulbophyllum peotinatum Pinet． has local anesthetic action.
Shi Rong: acrid in the mouth, light, cool in nature.Removing heat-phlegm, inducing diuresis to remove edema, eliminating stasis and resolving masses.For bronchitis, asthma, pulmonary tuberculosis, oedema due to nephritis, gastric cancer, esophageal carcinoma, hepatocarcinoma, breast carcinoma, pulmonary carcinoma; Traumatic injury is controlled in external, burn and scald, carbuncle furuncle.
Radix Malvae rotundifoliae: sweet in the mouth, warm in nature." Shaanxi Chinese herbal medicine " carries: " invigorating the spleen and replenishing QI, holder sore, diuresis, lactogenesis.Control asthenia, anemia, pulmonary tuberculosis, proctoptosis, uterine prolapse, oedema due to nephritis, diabetes, skin ulcer is swollen not easily passes through inside, hypogalactia." modern medicine study confirmation, the extract of Radix Malvae rotundifoliae root can suppress tubercule bacillus in vitro.
Radix didymospermatis caudati: sour in the mouth, puckery, cool in nature; Return lung, spleen channel.Cooling blood for hemostasis, convergence is solid de-.Cure mainly menorrhagia, metrorrhagia, spitting of blood, uterine prolapse.
Rhizoma alcasiae odorae: taste is micro-pungent, puckery, cold in nature, poisonous; GUIXIN, liver, gallbladder, large intestine channel.Heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, mass dissipating and swelling eliminating.Cure mainly influenza, flu, stomachache, pulmonary tuberculosis, rheumatic ostalgia, furuncle, swollen ulcer drug, scrofula, attached bone carbuncle, class is bald, scabies, worm venom.
The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature; Return lung, stomach, kidney channel.Matter profit gas and, fall and can rise.Cure mainly calentura high fever excessive thirst, cough due to lung-heat, laryngopharynx swelling and pain, osteopyrexia and fever, restlessness of asrhenia type and insomnia, stranguria with turbid discharge of quenching one's thirst, constipation." book on Chinese herbal medicine asks former " carries: " control hemoptysis, breathe heavily, drench, stomatosis, hematuria, inverse, night sweat, seminal emission, numbness flaccidity, clonic convulsion desert.”
Caulis et Folium Crotalariae Assamicae: lightly seasoned, cold in nature, poisonous; Return lung, spleen channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, inducing diuresis to remove edema.Cure mainly children's's head sore, aphtha, toothache, cough due to lung-heat spits blood, traumatic injury, traumatic hemorrhage, edema, renal calculus, cystitis, rheumatic ostalgia.Modern medicine study confirms, the monocrotaline that Caulis et Folium Crotalariae Assamicae includes can be synthesized and metabolism by tumoricidal albumen, thus promote its degeneration, have tumor cell and significantly suppress and destruction, have obvious suppression to have a karyokinesis or the proliferation of oncocyte.
Flos Gomphrenae: lightly seasoned, micro-sweet, property is put down.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, effectively can also treat amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury etc." Guangxi Chinese medicinal herbal " carries: " inflorescence, removing heat from blood is subsided a swelling, and relieving convulsion is coughed.Control pertussis; External treatment skin infection swells and ache.Among the peoplely control menoxenia.Herb pot water washout, controls traumatic injury furuncle.”
Radix Xylosmae japonici: bitter in the mouth, property is put down; Return liver, spleen channel.Detoxification and promoting urination, dissipating blood stasis is hastened parturition.Cure mainly jaundice, dysentery, edema, hemoptysis of pulmonary tuberculosis, scrofula, treating swelling and pain by traumatic injury, difficult labour, retention of dead fetus." conventional glossary of Herbs and Drugs among the people " carries: " dehumidifying, row liver network.Control vim and vigour stomachache.”
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention has effect of heat clearing and inflammation relieving, cooling blood for hemostasis, nourishing the lung to arrest cough, expelling wind and removing dampness, has significant therapeutic effect to the symptom such as cough, expectoration, spitting of blood, chest pain and uncomfortable in chest and dyspnea in various degree that treatment pulmonary tuberculosis causes.
2, choice of drug high-quality Chinese crude drug scientific compatibility of the present invention, easy to carry, safe and reliable, without any side effects, with low cost, can arrive the object for the treatment of both the principal and secondary aspects of a disease, is a kind of ideal medicament being used for the treatment of hemoptysis of pulmonary tuberculosis.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Herba potentillae fulgentis 80g Drymoglossum Herba Drymoglossi 77g Angiopteris magna Ching (Angiopteris majuscula Ching) 69g Herba Bulbophylli inconspicui 65g
Herba abutili indici 64g Auricularia 62g Cauliset Folium Piperis Hancei 62g Bulbophyllum peotinatum Pinet． 56g
Stone banyan 56g Radix Malvae rotundifoliae 52g Radix didymospermatis caudati 51g Rhizoma alcasiae odorae 45g
Rhizoma Anemarrhenae 43g Caulis et Folium Crotalariae Assamicae 40g Flos Gomphrenae 32g Radix Xylosmae japonici 29g.
Be used for the treatment of a preparation method for the medicine of hemoptysis of pulmonary tuberculosis, comprise following processing step:
(1) Herba potentillae fulgentis, Herba Bulbophylli inconspicui, Cauliset Folium Piperis Hancei and Shi Rong are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 7 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.11 ~ 1.13 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(2) Drymoglossum Herba Drymoglossi, Herba abutili indici, Auricularia, Bulbophyllum peotinatum Pinet．, Radix Malvae rotundifoliae, Radix didymospermatis caudati, Rhizoma alcasiae odorae, the Rhizoma Anemarrhenae and Flos Gomphrenae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.14 ~ 1.17, for subsequent use;
(3) Angiopteris magna Ching (Angiopteris majuscula Ching) and Caulis et Folium Crotalariae Assamicae are put into container, carry out pulverization process, grind into powder, cross 200 order fine powders, for subsequent use;
(4) by Radix Xylosmae japonici decontamination, section, dries, is placed in container, mixes well with wine, puts in pot to fry with slow fire to exhaust and micro-dry to wine, takes out, dries, be placed in mortar, grind into powder, cross 180 order fine powders for subsequent use;
(5) by the thick paste obtained by above-mentioned steps (1) ~ (4) and fine powder mixing, make capsule, obtain a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Herba potentillae fulgentis 75g Drymoglossum Herba Drymoglossi 72g Angiopteris magna Ching (Angiopteris majuscula Ching) 64g Herba Bulbophylli inconspicui 60g
Herba abutili indici 59g Auricularia 57g Cauliset Folium Piperis Hancei 55g Bulbophyllum peotinatum Pinet． 51g
Stone banyan 50g Radix Malvae rotundifoliae 47g Radix didymospermatis caudati 46g Rhizoma alcasiae odorae 40g
Rhizoma Anemarrhenae 38g Caulis et Folium Crotalariae Assamicae 35g Flos Gomphrenae 27g Radix Xylosmae japonici 25g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Herba potentillae fulgentis 71g Drymoglossum Herba Drymoglossi 68g Angiopteris magna Ching (Angiopteris majuscula Ching) 60g Herba Bulbophylli inconspicui 56g
Herba abutili indici 55g Auricularia 53g Cauliset Folium Piperis Hancei 51g Bulbophyllum peotinatum Pinet． 47g
Stone banyan 46g Radix Malvae rotundifoliae 42g Radix didymospermatis caudati 41g Rhizoma alcasiae odorae 36g
Rhizoma Anemarrhenae 34g Caulis et Folium Crotalariae Assamicae 31g Flos Gomphrenae 25g Radix Xylosmae japonici 23g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Herba potentillae fulgentis 67g Drymoglossum Herba Drymoglossi 64g Angiopteris magna Ching (Angiopteris majuscula Ching) 56g Herba Bulbophylli inconspicui 52g
Herba abutili indici 51g Auricularia 49g Cauliset Folium Piperis Hancei 47g Bulbophyllum peotinatum Pinet． 43g
Stone banyan 42g Radix Malvae rotundifoliae 37g Radix didymospermatis caudati 36g Rhizoma alcasiae odorae 32g
Rhizoma Anemarrhenae 30g Caulis et Folium Crotalariae Assamicae 27g Flos Gomphrenae 23g Radix Xylosmae japonici 21g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Herba potentillae fulgentis 62g Drymoglossum Herba Drymoglossi 59g Angiopteris magna Ching (Angiopteris majuscula Ching) 51g Herba Bulbophylli inconspicui 47g
Herba abutili indici 46g Auricularia 44g Cauliset Folium Piperis Hancei 42g Bulbophyllum peotinatum Pinet． 41g
Stone banyan 37g Radix Malvae rotundifoliae 32g Radix didymospermatis caudati 31g Rhizoma alcasiae odorae 27g
Rhizoma Anemarrhenae 25g Caulis et Folium Crotalariae Assamicae 22g Flos Gomphrenae 19g Radix Xylosmae japonici 17g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis, select the routine clinical observation of Patients with Cervical Spondylopathy 150 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 75 example, wherein male 37 example, women 38 example, 10 ~ 52 years old age, 31 years old mean age, the course of disease 6 months ~ 2 years; Matched group 75 example, wherein male 36 example, women 39 example, 11 ~ 51 years old age, 31 years old mean age, the course of disease 6 months ~ 1.5 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, take 2 ~ 4 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes carbazochrome salicylate, oral, and be grown up each 2.5 ~ 5mg, 3 times on the 1st, each 5 ~ 10mg of severe patient, 2 ~ 4 hours 1 time.
3, efficacy determination:
(1) cure: the symptom such as cough, expectoration, spitting of blood, chest pain, in various degree uncomfortable in chest or dyspnea all disappears, and physical recovery is normal.
(2) effective: cough, expectoration, spitting of blood, the symptom such as chest pain, in various degree uncomfortable in chest or dyspnea obviously alleviate, and health takes a turn for the better to some extent.
(3) effective: the symptom such as cough, expectoration, spitting of blood, chest pain, in various degree uncomfortable in chest or dyspnea alleviates to some extent, and health is clearly better.
(4) invalid: by treating rear above-mentioned symptom without alleviating or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Peng, female, 50 years old, people from Zhuhai, Guangdong.Patient suffers from pulmonary tuberculosis and breaks out and have Massive hemoptysis phenomenon.Children are sent in a hurry hospital treatment, repeatedly occur over the course for the treatment of repeatedly spitting blood.Symptom allows of no optimist.Rear patient, under doctor advised, starts to take medicine of the present invention, and after taking 2 courses for the treatment of, the state of an illness tends towards stability gradually, and after continuing to take 2 courses for the treatment of, the state of an illness is fully recovered, and follows up a case by regular visits to and has no recurrence.
2, Feng, man, 48 years old, people from Chengdu, Sichuan.Patient's last August CT examination display patient suffers from pulmonary tuberculosis, and by normal therapeutic 1 year, the state of an illness was not felt any better, and CT examination finds that focus change is little again, but still hemoptysis, and doctor changes therapeutic scheme state of an illness still without taking a turn for the better to it.Under doctor advised, go to me and institute treat, the court doctor, according to its concrete situation, advises it to take medicine of the present invention, and after taking 3 courses for the treatment of, conditions of patients is fully recovered, and through CT examination, pulmonary tuberculosis is fully recovered, and physical recovery is healthy.
3, certain is thanked, female, 62 years old, people from Changsha.Patient suffers from pulmonary tuberculosis for many years, and seek treatment method always, and Drug therapy all to no effect in many ways.Patient was once in despair.Under friend recommendation, come me and institute go to a doctor, doctor does CT examination for it, and after inspection, doctor determines to give patient Drug therapy of the present invention according to the passing medication of patient and therapeutic modality.After taking 1 course for the treatment of of medicine of the present invention, the patient fundamental symptomss such as haematemesis that spit blood disappear, and continue to take 3 courses for the treatment of, the state of an illness is fully recovered, and CT examination health is completely healthy, and no sequel occurs.
4, all certain, man, 35 years old, people from Wuhan, Hubei.Patient started to occur the symptom such as heating, chest pain, cough, bloody sputum before half a year, after to be admitted to hospital diagnosis and treatment, be diagnosed as flu.After taking medicine, start to occur low grade fever, afternoon body temperature increases, and cough aggravation, sputum mixed with blood, has obvious anorexia, become thin, the symptoms such as Sleep hyperhidrosis.Rear patient goes to my institute and goes to a doctor, and diagnosis is pulmonary tuberculosis, treats in time through doctor, starts to take medicine of the present invention, and take 3 courses for the treatment of of medicine of the present invention, patient fully recovers, and in disease, the state of an illness is without infection phenomenon.
5, certain is revived, female, 45 years old, people from Weihai in Shandong province.Patient is diagnosed out patient to have far advanced tuberculosis in a medicine body, and in time after treatment, the state of an illness tends towards stability, but occasionally has spitting of blood phenomenon to occur, recommend to start to take medicine of the present invention, after taking 3 courses for the treatment of, through CT examination through doctor, conditions of patients is fully recovered, and follows up a case by regular visits to after half a year, without recurrence.
6, certain is turned round and look at, man, 28 years old, people from Foochow, Fujian.Patient often stays up late and sees a film or play games, and rear beginning feels uncomfortable, often has a fever without reason, coughs, and sometimes occurs hemoptysis phenomenon, in a hurry admission examination.Through the display of doctor's CT examination, the shade of the foxtail millet grain size that patient two lung is dispersed in, equal density in the same size, the granular shade of the foxtail millet be evenly distributed is acute military tuberculosis.Patient is hospitalization always, has no positive effect, after doctor recommend under, come me and institute go to a doctor, doctor gives patient and takes medicine of the present invention, takes medicine 3 courses for the treatment of, patient fully recover, no sequel occur.
Claims (5)
1. be used for the treatment of a medicine for hemoptysis of pulmonary tuberculosis, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 58 ~ 84 parts of Drymoglossum Herba Drymoglossis 55 ~ 81 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 47 ~ 73 parts of Herba Bulbophylli inconspicui 42 ~ 69 parts
Herba abutili indici 42 ~ 68 parts of Auricularia 38 ~ 67 Fen Cauliset Folium Piperis Hancei 38 ~ 67 parts of Bulbophyllum peotinatum Pinet． 34 ~ 61 parts
Stone banyan 33 ~ 60 parts of Radix Malvae rotundifoliaes 28 ~ 57 parts of Radix didymospermatis caudati 26 ~ 56 portions of Rhizoma alcasiae odoraes 22 ~ 50 parts
The Rhizoma Anemarrhenae 21 ~ 47 parts of Caulis et Folium Crotalariae Assamicaes 18 ~ 44 parts of Flos Gomphrenaes 15 ~ 36 parts of Radix Xylosmae japonicis 13 ~ 32 parts.
2. a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 62 ~ 80 parts of Drymoglossum Herba Drymoglossis 59 ~ 77 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 51 ~ 69 parts of Herba Bulbophylli inconspicui 47 ~ 65 parts
Herba abutili indici 46 ~ 64 parts of Auricularia 44 ~ 62 Fen Cauliset Folium Piperis Hancei 42 ~ 62 parts of Bulbophyllum peotinatum Pinet． 41 ~ 56 parts
Stone banyan 37 ~ 56 parts of Radix Malvae rotundifoliaes 32 ~ 52 parts of Radix didymospermatis caudati 31 ~ 51 portions of Rhizoma alcasiae odoraes 27 ~ 45 parts
The Rhizoma Anemarrhenae 25 ~ 43 parts of Caulis et Folium Crotalariae Assamicaes 22 ~ 40 parts of Flos Gomphrenaes 19 ~ 32 parts of Radix Xylosmae japonicis 17 ~ 29 parts.
3. a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 67 ~ 75 parts of Drymoglossum Herba Drymoglossis 64 ~ 72 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 56 ~ 64 parts of Herba Bulbophylli inconspicui 52 ~ 60 parts
Herba abutili indici 51 ~ 59 parts of Auricularia 49 ~ 57 Fen Cauliset Folium Piperis Hancei 47 ~ 55 parts of Bulbophyllum peotinatum Pinet． 43 ~ 51 parts
Stone banyan 42 ~ 50 parts of Radix Malvae rotundifoliaes 37 ~ 47 parts of Radix didymospermatis caudati 36 ~ 46 portions of Rhizoma alcasiae odoraes 32 ~ 40 parts
The Rhizoma Anemarrhenae 30 ~ 38 parts of Caulis et Folium Crotalariae Assamicaes 27 ~ 35 parts of Flos Gomphrenaes 23 ~ 27 parts of Radix Xylosmae japonicis 21 ~ 25 parts.
4. a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba potentillae fulgentis 71 parts of Drymoglossum Herba Drymoglossis 68 parts of Angiopteris magna Ching (Angiopteris majuscula Ching)s 60 parts of Herba Bulbophylli inconspicui 56 parts
Herba abutili indici 55 parts of Auricularia 53 Fen Cauliset Folium Piperis Hancei 51 parts of Bulbophyllum peotinatum Pinet． 47 parts
Stone banyan 46 parts of Radix Malvae rotundifoliaes 42 parts of Radix didymospermatis caudati 41 portions of Rhizoma alcasiae odoraes 36 parts
The Rhizoma Anemarrhenae 34 parts of Caulis et Folium Crotalariae Assamicaes 31 parts of Flos Gomphrenaes 25 parts of Radix Xylosmae japonicis 23 parts.
5. as described in any one of Claims 1 to 4, be used for the treatment of a preparation method for the medicine of hemoptysis of pulmonary tuberculosis, it is characterized in that: comprise following processing step:
(1) Herba potentillae fulgentis, Herba Bulbophylli inconspicui, Cauliset Folium Piperis Hancei and Shi Rong are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 7 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.11 ~ 1.13 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(2) Drymoglossum Herba Drymoglossi, Herba abutili indici, Auricularia, Bulbophyllum peotinatum Pinet．, Radix Malvae rotundifoliae, Radix didymospermatis caudati, Rhizoma alcasiae odorae, the Rhizoma Anemarrhenae and Flos Gomphrenae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.14 ~ 1.17, for subsequent use;
(3) Angiopteris magna Ching (Angiopteris majuscula Ching) and Caulis et Folium Crotalariae Assamicae are put into container, carry out pulverization process, grind into powder, cross 200 order fine powders, for subsequent use;
(4) by Radix Xylosmae japonici decontamination, section, dries, is placed in container, mixes well with wine, puts in pot to fry with slow fire to exhaust and micro-dry to wine, takes out, dries, be placed in mortar, grind into powder, cross 180 order fine powders for subsequent use;
(5) by the thick paste obtained by above-mentioned steps (1) ~ (4) and fine powder mixing, make capsule, obtain described a kind of medicine being used for the treatment of hemoptysis of pulmonary tuberculosis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410063000.6A CN103768396B (en) | 2014-02-22 | 2014-02-22 | A kind of medicine and preparation method being used for the treatment of hemoptysis of pulmonary tuberculosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410063000.6A CN103768396B (en) | 2014-02-22 | 2014-02-22 | A kind of medicine and preparation method being used for the treatment of hemoptysis of pulmonary tuberculosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103768396A CN103768396A (en) | 2014-05-07 |
| CN103768396B true CN103768396B (en) | 2016-01-20 |
Family
ID=50561456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410063000.6A Expired - Fee Related CN103768396B (en) | 2014-02-22 | 2014-02-22 | A kind of medicine and preparation method being used for the treatment of hemoptysis of pulmonary tuberculosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103768396B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383398A (en) * | 2014-11-13 | 2015-03-04 | 朱海燕 | Traditional Chinese medicine composition for treating hemoptysis and preparation method and application thereof |
| CN105596923A (en) * | 2015-11-10 | 2016-05-25 | 夏放军 | Traditional Chinese medicine decoction used for treating pulmonary tuberculosis, and preparation method thereof |
| CN105796959A (en) * | 2016-03-24 | 2016-07-27 | 范厚翠 | Traditional Chinese medicine preparation for treating tuberculosis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045143A (en) * | 2006-03-28 | 2007-10-03 | 李延生 | Medicine for quickly treating high fever due to tuberculosis and pneumonitis and its preparing method |
| CN102935174A (en) * | 2012-11-16 | 2013-02-20 | 卜文红 | Chinese medicinal composition for treating parotitis |
-
2014
- 2014-02-22 CN CN201410063000.6A patent/CN103768396B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101045143A (en) * | 2006-03-28 | 2007-10-03 | 李延生 | Medicine for quickly treating high fever due to tuberculosis and pneumonitis and its preparing method |
| CN102935174A (en) * | 2012-11-16 | 2013-02-20 | 卜文红 | Chinese medicinal composition for treating parotitis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103768396A (en) | 2014-05-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103768396B (en) | A kind of medicine and preparation method being used for the treatment of hemoptysis of pulmonary tuberculosis | |
| CN104258151A (en) | Drug for treating nephropyelitis and preparation method thereof | |
| CN103877377A (en) | Chinese medicament preparation for treating lymphoma and preparation method of Chinese medicament preparation | |
| CN103830673B (en) | A kind of Chinese medicine preparation treating gastric abscess and preparation method | |
| CN104435454A (en) | Medicine for treating chronic endometritis and preparation method of medicine | |
| CN104288745A (en) | Traditional Chinese medicine for treating CG (Chronic Gastritis) | |
| CN103893495A (en) | Traditional Chinese medicine liquid for treating skin itch and preparation method | |
| CN103735780B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis | |
| CN103860682B (en) | One treats phthisical Chinese medicine preparation and preparation method | |
| CN103877336B (en) | A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain | |
| CN104398904B (en) | Chinese herbal preparation for oral care after esophagus cancer surgery and preparation method | |
| CN103893491B (en) | A kind of medicine and preparation method for the treatment of cyclomastopathy | |
| CN103877397B (en) | A kind of medicine of radiotherapy injury of lung and preparation method | |
| CN103877390A (en) | Traditional-Chinese-medicine preparation for treating rheumatic fever and preparation method thereof | |
| CN103536705B (en) | A kind of Chinese medicine composition for the treatment of colitis | |
| CN103550520B (en) | Traditional Chinese medicinal preparation for treating gastric ulcer and preparation method thereof | |
| CN104258147A (en) | Traditional Chinese medicine preparation for treating breast liposarcoma and preparation method of traditional Chinese medicine preparation | |
| CN104208380A (en) | Capsule for treating septicemia and preparation method | |
| CN105616760A (en) | Traditional Chinese medicine preparation for treating chronic pharyngitis and preparation method | |
| CN105395879A (en) | Traditional Chinese medicine used for treating senile chronic bronchitis | |
| CN104645102A (en) | Traditional Chinese medicine preparation for treating esophagitis and preparation method of traditional Chinese medicine preparation | |
| CN103919919A (en) | Chinese herba preparation for treating cold, as well as preparation method thereof | |
| CN104173807A (en) | Medicament for treating virus meningitis and preparation method thereof | |
| CN103919970B (en) | A kind of Chinese medicine preparation treating infantile bronchitis and preparation method | |
| CN103735912B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of laryngopharyngitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Tian Jianguo Inventor before: Wang Guimei Inventor before: Qu Limei Inventor before: Wang Yuguo Inventor before: Di Xiju |
|
| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170824 Address after: 061100, room 1, unit 1, family planning bureau, bureau of community planning, Bohai West Road, Huanghua, Hebei, 102 Patentee after: Tian Jianguo Address before: 271000 No. 262 Tai Dong Road, Daiyue District, Shandong, Tai'an Patentee before: Wang Guimei |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160120 Termination date: 20180222 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |