CN104398904B - Chinese herbal preparation for oral care after esophagus cancer surgery and preparation method - Google Patents
Chinese herbal preparation for oral care after esophagus cancer surgery and preparation method Download PDFInfo
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- CN104398904B CN104398904B CN201410772801.XA CN201410772801A CN104398904B CN 104398904 B CN104398904 B CN 104398904B CN 201410772801 A CN201410772801 A CN 201410772801A CN 104398904 B CN104398904 B CN 104398904B
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Abstract
The invention discloses a Chinese herbal preparation for oral care after an esophagus cancer surgery. The Chinese herbal preparation is composed of the following raw materials adopted as active ingredients: Scutellaria indica, carambola, Chinese alpine rush, indian lettuce, Polygonum senticosum, wild winter chrysanthemum, Chinese black olive, Polygonum tinctorium fruit, Physalis angulata, ardisia crispa, Forsythia suspensa, cherry stone, C.sinensis O.Ktze.var.maerophylla Sieb, Rhizome of Whorledleaf Solomonseal, Vitis bryoniifolia and borneol. The Chinese herbal preparation adopts Chinese herbal medicine as the active ingredients, is good in drug compatibility of the selected herbs, has the functions of clearing away heat and toxic material, relieving sore throat, dispersing blood stasis, reducing swelling, diminishing inflammation and relieving pain by combining the active ingredients, can quickly promote healing of ulcerated wounds, is obvious in curative effect, low in price and easy to prepare, has the advantages of being high in efficiency, high in cure rate, free of toxic and side effects, safe, convenient and the like on esophagus cancer postoperative recovery, and can be widely used for esophagus cancer postoperative recovery.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for the postoperative mouth care of esophageal carcinoma and preparation method.
Background technology
The esophageal carcinoma is common digestive tract tumor, and the whole world about has 300,000 people to die from the esophageal carcinoma every year.Its M & M various countries are widely different.China is one of Esophageal Cancer area in the world, and every annual is died of illness about 150,000 people.Man is more than female, and age of onset is many more than 40 years old.The typical symptom of the esophageal carcinoma is Progressive symmetric erythrokeratodermia acataposis, before this food of difficult dry pharynx, is semiliquid diet then, and last water and saliva can not be swallowed.
Esophageal carcinoma early symptom is often not obvious, but may have discomfort sensation in various degree when swallowing thick and stiff food, comprises ingest food choking feeling, burns sample, acupuncture sample or tractive friction sample pain after breastbone.Food by slow, and has stagnation sense or foreign body sensation.Stalk is choked to stagnate to feel and alleviate disappearance after being swallowed water.Heavy time light during symptom, make slow progress.The typical symptom of advanced esophageal carcinoma is Progressive symmetric erythrokeratodermia acataposis, before this food of difficult dry pharynx, is semiliquid diet then, and last water and saliva can not be swallowed.Often telling mucoid expectorant, is the saliva of hypopharynx and the secretions of esophagus.Patient becomes thin gradually, dewater, unable.Lasting chest pain or backache are expressed as symptom in late period, and cancer has been invaded esophagus and organized outward.
When cancerous protuberance blocks caused inflammation edema transient remission, or after part cancerous protuberance comes off, obstruction can temporarily alleviate, and constant error thinks that sb.'s illness took a favorable turn.If cancerous protuberance invades recurrent laryngeal nerve, hoarseness can be there is; If compressing cervical sympathetic ganglia, Horner syndrome can be produced; If intrusion trachea-bronchial epithelial cell, esophagus, trachea or bronchial fistula can be formed, acutely choke when occurring swallowing water or food and cough, and respiratory system infection occurs.Finally there is cachectic states.If there is the Organ relative weight such as liver, brain, the states such as jaundice, seroperitoneum, stupor can be there is.
The method mainly operative treatment of current treatment esophageal carcinoma.Along with the development of modern medicine, postoperative care is also paid attention to gradually, after nursing, carry out the recovery of correct nursing for disease by significant to patient affected part, we need to develop a kind of Chinese medicine and help postoperative assisted care for this reason.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the postoperative mouth care of esophageal carcinoma and preparation method; Chinese medicine preparation of the present invention adopts Chinese herbal medicine to be effective ingredient, selected medical material compatibility is suitable, all medicines are harmonious and have effect of heat-clearing and toxic substances removing, relieving sore-throat by clearing away heat, dissipating blood stasis for subsidence of swelling, anti-inflammatory analgetic, the wound healing that festers can be promoted fast, determined curative effect, for have for esophageal carcinoma post-operative recovery instant effect, cure rate high, have no side effect, the advantage such as safe ready, and low price, easy preparation, can be widely used in esophageal carcinoma post-operative recovery.
For achieving the above object, technical scheme of the present invention is implemented as follows:
For a Chinese medicine preparation for esophageal carcinoma post-operative recovery, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 33-65 part Fructus Averrhoae Carambolae 31-63 part Chinese alpine rush 31-63 part Herba Ixeritis Denticulatae 29-61 part
Herba polygoni senticosi 29-53 part Aster oreophilus Franch 28-52 part Fructus Canarii Pimelae 27-51 part Fructus polygoni tinctorii 23-47 part
Herba Physalis pubescentis 21-45 part Radix Ardisiae Crispae 21-45 part Fructus Forsythiae 18-38 part Nux Pruni pseudocerasi 18-38 part
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 17-37 part Rhizoma Polygonati Verticillati 15-35 Fen Caulis et folium vitis thunbergii 13-33 part Borneolum Syntheticum 11-31 part.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 57 parts of Fructus Averrhoae Carambolaes 55 portions of Chinese alpine rush 55 parts of Herba Ixeritis Denticulataes 53 parts
Herba polygoni senticosi 47 parts of Aster oreophilus Franch 46 portions of Fructus Canarii Pimelaes 45 parts of Fructus polygoni tinctorii 41 parts
Herba Physalis pubescentis 39 parts of Radix Ardisiae Crispaes 39 parts of Fructus Forsythiaes 33 parts of Nux Pruni pseudocerasis 33 parts
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 32 parts of Rhizoma Polygonati Verticillati 30 Fen Caulis et folium vitis thunbergii 28 parts of Borneolum Syntheticums 26 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 49 parts of Fructus Averrhoae Carambolaes 47 portions of Chinese alpine rush 47 parts of Herba Ixeritis Denticulataes 45 parts
Herba polygoni senticosi 41 parts of Aster oreophilus Franch 40 portions of Fructus Canarii Pimelaes 39 parts of Fructus polygoni tinctorii 35 parts
Herba Physalis pubescentis 33 parts of Radix Ardisiae Crispaes 33 parts of Fructus Forsythiaes 28 parts of Nux Pruni pseudocerasis 28 parts
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 27 parts of Rhizoma Polygonati Verticillati 25 Fen Caulis et folium vitis thunbergii 23 parts of Borneolum Syntheticums 21 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 41 parts of Fructus Averrhoae Carambolaes 39 portions of Chinese alpine rush 39 parts of Herba Ixeritis Denticulataes 37 parts
Herba polygoni senticosi 35 parts of Aster oreophilus Franch 34 portions of Fructus Canarii Pimelaes 33 parts of Fructus polygoni tinctorii 29 parts
Herba Physalis pubescentis 27 parts of Radix Ardisiae Crispaes 27 parts of Fructus Forsythiaes 23 parts of Nux Pruni pseudocerasis 23 parts
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 22 parts of Rhizoma Polygonati Verticillati 20 Fen Caulis et folium vitis thunbergii 18 parts of Borneolum Syntheticums 16 parts.
For a preparation method for the Chinese medicine preparation of esophageal carcinoma post-operative recovery, comprise following processing step:
(1) by Herba Scutellariae indicae with Herba Physalis pubescentis is cleaned, put into container, smash to pieces, stay juice for subsequent use;
(2) by Fructus Averrhoae Carambolae, Chinese alpine rush, Herba Ixeritis Denticulatae, Aster oreophilus Franch, Fructus Canarii Pimelae, Fructus polygoni tinctorii, Radix Ardisiae Crispae, Fructus Forsythiae, Nux Pruni pseudocerasi, Camellia sinensis O. Ktze. Var. macrophylla Sieb. with Caulis et folium vitis thunbergii puts into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge extractive liquid, filters, filtrate is condensed into the thick paste of relative density 1.10 ~ 1.15 at 60 DEG C, for subsequent use;
(3) Herba polygoni senticosi and Rhizoma Polygonati Verticillati are dried, grind into powder, cross 120 order fine powders, for subsequent use;
(4) ethanol of Borneolum Syntheticum 5ml90% is melted, obtain solution for standby;
(5) fine powder that thick paste juice obtained for step (1), step (2) obtained, step (3) are obtained and the solution mixing that step (4) obtains, make tablet, be the Chinese medicine preparation for the postoperative mouth care of esophageal carcinoma of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Scutellariae indicae: acrid in the mouth, hardship, bosom is cold; GUIXIN, liver, lung meridian.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, hemostasia and detumescence.Main carbuncle furunculosis, lung abscess, acute appendicitis, scrofula, venom, lung-heat cough with asthma, toothache, sore throat, pharyngalgia, bones and muscles pain, spits blood, and spitting of blood, has blood in stool, traumatic injury, wound hemorrhage, skin pruritus." Quanzhou book on Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, Huang is moved back in detumescence, by blood removing blood stasis with potent drugs, removing pus and relieving carbuncle, cooling blood for hemostasis, throat.Cure mainly all larynxs Huang, also control lung-fire height dyspnea of heat type and cough, spit blood, hemoptysis is spat blood, and crazy blood is had a pain, and knife injury is hemorrhage, malignant boil carbuncle, tiger, lyssodexis.”
Fructus Averrhoae Carambolae: sour in the mouth, sweet, cold in nature; Attach to the lung and stomach meridians.Heat clearing away, promotes the production of body fluid, diuretic, removing toxic substances.Main air heat cough, pharyngalgia, excessive thirst, stranguria caused by urinary stone, erosion of the oral mucosa, toothache, malaria with splenomegaly, alcoholism." south of the Five Ridges gather medicinal herbs record " carries: " quenching the thirst, it is tired to separate, and heat extraction, diuresis, except children's's erosion of mucous membrane of the oral cavity, controls venom disease.”
Chinese alpine rush: sweet in the mouth, light; Cool in nature.Heat-clearing and toxic substances removing, cool the blood dissipate blood stasis.Main flu, infantile pneumonia, pulmonary tuberculosis is spat blood, epistaxis, hematuria, blockage of menstruation, pyretic stranguria, mastitis, urticaria, traumatic hemorrhage.
Herba Ixeritis Denticulatae: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Main carbuncle furuncle parent poison, acute mastitis, laryngopharynx swelling and pain, jaundice, dysentery, stranguria, leukorrhagia, traumatic injury." Wenling county Chinese medicine preparation resource register " carries: " refreshing and detoxicating, eliminating carbuncle eliminating stagnation.Control venom, lung abscess, furuncle and phyma, traumatic injury.”
Herba polygoni senticosi: bitter in the mouth, acid, micro-pungent, property is put down.Heat-clearing and toxic substances removing, and wet antipruritic, dissipating blood stasis for subsidence of swelling.Main carbuncle skin ulcer furuncle furuncle, venom, eczema, impetigo, herpes zoster, traumatic injury, pleased, internal hemorrhoid external hemorrhoid." Gansu Chinese herbal medicine handbook " carries: " heat-clearing and toxic substances removing, regulating QI to relieve pain, Gu de-.Control infantile carbuncle, gastric qi pain, uterine prolapse.”
Aster oreophilus Franch: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Main conjunctival congestion and swelling pain, coffee larynx pain, stomatitis, toothache.
Fructus Canarii Pimelae: sour in the mouth, puckery, property is put down; Return spleen, lung meridian.Hemostasis, diuretic, removing toxic substances.Main hematmesis due to visceral injury, cough expectorant blood, edema, acute mastitis, traumatic hemorrhage." south of the Five Ridges gather medicinal herbs record " carries: " sustainability forged by fire, hemostasis and phlegm.Few salting it, name olive drum, acute mastitis from the beginning of, decoct can disappearing of washing.”
Fructus polygoni tinctorii: sweet in the mouth, hardship, cold in nature; Return Liver Channel.Heat clearing away, removing heat from blood, removing toxic substances.The high heat of main epidemic febrile disease, tells nosebleed, sends out speckle, laryngopharynx swelling and pain, furuncle and phyma, innominate toxic swelling, infantile malnutrition phagedenoma, honeybee insect sting." property of medicine opinion " carries: " fill out bone marrow, improve visual and auditory acuity, sharp the five internal organs, adjust six internal organs, sharp joint.Control stagnation of QI in meridians, people is good for, sleeps less, beneficial mental and physical efforts.”
Herba Physalis pubescentis: bitter in the mouth, acid, cold in nature.Heat clearing away, diuresis, removing toxic substances, detumescence.Main flu, cough due to lung-heat, laryngopharynx swelling and pain, gingival swelling and pain, jaundice due to damp-heat, dysentery, edema, pyretic stranguria, pemphigus, furuncle." Chinese herbal medicine is commonly used in Shanghai " carries: " heat-clearing and toxic substances removing, diuresis is stopped blooding, dispersing swelling and dissipating binds.Control laryngopharynx swelling and pain, lung abscess, parotitis; Dysuria, hematuria.Gingival swelling and pain, pemphigus.”
Radix Ardisiae Crispae: bitter in the mouth, pungent, cool in nature.Relieving sore-throat by clearing away heat, eliminate the phlegm dampness removing, promoting blood circulation and detoxication.Main laryngopharynx swelling and pain, cough is coughed up phlegm not smooth, jaundice due to damp-heat, urine leaching pain, rheumatic arthralgia, traumatic injury, furuncle, innominate toxic swelling, venom." Tian Bao book on Chinese herbal medicine " carries: " control pharyngitis, the swollen pain of periodontal disease.”
Fructus Forsythiae: bitter in the mouth, cold nature; Return lung, the heart, gallbladder meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, anemopyretic cold.Main anemopyretic cold, epidemic febrile disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat.Shennong's Herbal carries: " main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat." modern medicine study confirmation, Volatile Oil of Forsythia Suspensa Seeds Emulsion is carried out antibacterial tests with test tube times amount dilution method, and result shows this medicine except slightly low to bacillus pyocyaneus effect, all has stronger antibacterial action to other 10 strain Gram-positive and negative bacteria.
Nux Pruni pseudocerasi: acrid in the mouth, warm in nature; Return lung meridian.Deliver rash, dispersing tumor goes scar, promoting the circulation of QI to relieve pain.The main varioliform exanthema initial stage is sent out not smooth thoroughly, cicatrix of skin, goiter, hernia pain." book on Chinese herbal medicine is new again " carries: " relieve internal heat, the cellulitis that disappears tumor.”
Camellia sinensis O. Ktze. Var. macrophylla Sieb.: bitter in the mouth, cold in nature; GUIXIN, liver, lung, urinary bladder channel.Clearing heat and relieving fidgetness, quenches the thirst, improving eyesight.Main dysphoria with smothery sensation headache, thirsty, blurred vision, laryngopharynx swelling and pain, drenches pain." detailed outline " carries: " hold in the mouth or the eyes the clear postcibal vomiting of pharynx, throat.”
Rhizoma Polygonati Verticillati: sweet in the mouth, micro-hardship, cool in nature.Spleen reinforcing lung moistening, nourishing the liver, removing toxicity for eliminating carbuncles.Main weakness of the spleen and stomach, lung-dryness syndrome due to deficiency of YIN, cough dry pharynx, excessive rising of liver-YANG, has a dizzy spell, sore, carbuncle and painful swelling." Shaanxi Chinese herbal medicine " carries: " suppressing the hyperactive liver to relieve the wind syndrome, yin nourishing improving eyesight, clearing away heat and cooling blood.Control headache order disease, throat pain, vascular hypertension ， epilepsy, furuncle carbuncle.”
Caulis et folium vitis thunbergii: sweet in the mouth, acid, property is put down; Return liver, stomach warp.Heat-clearing and toxic substances removing, expelling wind and removing dampness.For hepatitis, appendicitis, mastitis, lung abscess, multiple abscess, rheumatic arthritis; Sore swollen toxin is controlled in external, otitis media, snake bite and insect sting." Fujian Chinese herbal medicine " carries: " cooling blood for hemostasis, subduing swelling and detoxicating.”
Borneolum Syntheticum: acrid in the mouth, hardship, cold nature; GUIXIN, spleen, lung meridian.To have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated." detailed outline " carries: " treat sore throat, headache, breath, toothache, typhoid fever protrusion of the tongue, children's's pox falls into.Logical all keys, loose stagnated fire.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention adopts Chinese herbal medicine to be effective ingredient, selected medical material compatibility is suitable, all medicines are harmonious and have effect of heat-clearing and toxic substances removing, relieving sore-throat by clearing away heat, dissipating blood stasis for subsidence of swelling, anti-inflammatory analgetic, the wound healing that festers can be promoted fast, determined curative effect, for have for esophageal carcinoma post-operative recovery instant effect, cure rate high, have no side effect, the advantage such as safe ready, and low price, easy preparation, can be widely used in esophageal carcinoma post-operative recovery.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Scutellariae indicae 63g Fructus Averrhoae Carambolae 62g Chinese alpine rush 62g Herba Ixeritis Denticulatae 60g
Herba polygoni senticosi 52g Aster oreophilus Franch 51g Fructus Canarii Pimelae 50g Fructus polygoni tinctorii 46g
Herba Physalis pubescentis 43g Radix Ardisiae Crispae 43g Fructus Forsythiae 37g Nux Pruni pseudocerasi 37g
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 36g Rhizoma Polygonati Verticillati 34g Caulis et folium vitis thunbergii 32g Borneolum Syntheticum 30g.
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) by Herba Scutellariae indicae with Herba Physalis pubescentis is cleaned, put into container, smash to pieces, stay juice for subsequent use;
(2) by Fructus Averrhoae Carambolae, Chinese alpine rush, Herba Ixeritis Denticulatae, Aster oreophilus Franch, Fructus Canarii Pimelae, Fructus polygoni tinctorii, Radix Ardisiae Crispae, Fructus Forsythiae, Nux Pruni pseudocerasi, Camellia sinensis O. Ktze. Var. macrophylla Sieb. with Caulis et folium vitis thunbergii puts into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge extractive liquid, filters, filtrate is condensed into the thick paste of relative density 1.10 ~ 1.15 at 60 DEG C, for subsequent use;
(3) Herba polygoni senticosi and Rhizoma Polygonati Verticillati are dried, grind into powder, cross 120 order fine powders, for subsequent use;
(4) ethanol of Borneolum Syntheticum 5ml90% is melted, obtain solution for standby;
(5) fine powder that thick paste juice obtained for step (1), step (2) obtained, step (3) are obtained and the solution mixing that step (4) obtains, make tablet, be the Chinese medicine preparation for the postoperative mouth care of esophageal carcinoma of the present invention.
Usage and dosage: oral, every day 3 times, each 27 days is a course for the treatment of, and the lighter can fully recover 2 to 4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Scutellariae indicae 57g Fructus Averrhoae Carambolae 55g Chinese alpine rush 55g Herba Ixeritis Denticulatae 53g
Herba polygoni senticosi 47g Aster oreophilus Franch 46g Fructus Canarii Pimelae 45g Fructus polygoni tinctorii 41g
Herba Physalis pubescentis 39g Radix Ardisiae Crispae 39g Fructus Forsythiae 33g Nux Pruni pseudocerasi 33g
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 32g Rhizoma Polygonati Verticillati 30g Caulis et folium vitis thunbergii 28g ice bag 26g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Scutellariae indicae 49g Fructus Averrhoae Carambolae 47g Chinese alpine rush 47g Herba Ixeritis Denticulatae 45g
Herba polygoni senticosi 41g Aster oreophilus Franch 40g Fructus Canarii Pimelae 39g Fructus polygoni tinctorii 35g
Herba Physalis pubescentis 33g Radix Ardisiae Crispae 33g Fructus Forsythiae 28g Nux Pruni pseudocerasi 28g
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 27g Rhizoma Polygonati Verticillati 25g Caulis et folium vitis thunbergii 23g Borneolum Syntheticum 21g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Scutellariae indicae 41g Fructus Averrhoae Carambolae 39g Chinese alpine rush 39g Herba Ixeritis Denticulatae 37g
Herba polygoni senticosi 35g Aster oreophilus Franch 34g Fructus Canarii Pimelae 33g Fructus polygoni tinctorii 29g
Herba Physalis pubescentis 27g Radix Ardisiae Crispae 27g Fructus Forsythiae 23g Nux Pruni pseudocerasi 23g
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 22g Rhizoma Polygonati Verticillati 20g Caulis et folium vitis thunbergii 18g Borneolum Syntheticum 16g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of esophageal carcinoma, select the routine clinical observation of esophageal cancer patients 200 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 100 example, wherein male 50 example, women 50 example, age 30-78 year, 40 years old mean age, the course of disease 2 months-10 years; Matched group 100 example, wherein male 50 example, women 50 example, age 30-70 year, 35 years old mean age, the course of disease 2 months-8 years.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, Therapeutic Method:
Treatment group patient takes Chinese medicine preparation of the present invention, every day 3 times, each 2, and warm water delivery service in half an hour after meal 7 days is a course for the treatment of, and taking 2 to 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
It is flat loose that matched group takes esophagus, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: pain, acupuncture sample or tractive friction sample pain after swallowing choking feeling, breastbone and under xiphoid-process, become thin, dewater, the transference cure such as unable, physical recovery is normal.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of Chinese medicine preparation of the present invention, cure 76 examples, effective 21 examples, invalid 3 examples, cure rate is 76%, total effective rate 97%.
Cure 30 examples in matched group, effective 29 examples, invalid 41 examples, cure rate is 30%, total effective rate 59%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Shandong, female, 62 years old, retired worker, Tianshui city people.Patient because of the pharyngeal inconvenience that occurs having a meal, drink water unobstructed, gas is smooth, have the symptoms such as foreign body sensation to our hospital.Be diagnosed as esophageal carcinoma on inspection.Carry out esophageal carcinoma Post operation, take 2 courses for the treatment of of Chinese medicine preparation of the present invention, pick body; Continue to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur, thoroughly cure.
2, Song, man, 42 years old, peasant, people from Datong.Patient suffers from esophageal carcinoma more than 1 year, and there is western medicine period, and food can only eat paste like food, and drinking-water is comparatively light, and gas is smooth, and esophagus has foreign body sensation strong and adjoint pain.Implementing Post operation is that 3 courses for the treatment of of Chinese medicine preparation of the present invention are taken in after treatment, and health starts to take a turn for the better; Continue to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur, thoroughly cure.
3, Lin, man, 38 years old, manager, District, Xinyang Area, Henan Province people.Before half a year there is dysphagia without obvious inducement in patient, water inlet sense of obstruction, and once sought medical advice in local hospital, outpatient service gastroscopy, is diagnosed as " esophageal carcinoma ", do not take a favorable turn, proceed to my institute after local hospital treatment.Implement Post operation in my institute and take 2 courses for the treatment of of Chinese medicine preparation of the present invention, health takes a turn for the better; After continuing to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
4, paddy, female, 46 years old, peasant, people from Guangan, Sichuan.Patient feels sense of choking with sobs when taking food before 2 years, then has the performances such as retrosternal pain, and closely over the past half year, drinking gruel also has similar sensation, does not take food and also has foreign body in esophagus sense, occurs hoarseness, the symptom such as out of breath simultaneously.Then to our hospital, be diagnosed as esophageal carcinoma on inspection.Carry out Post operation and take 2 courses for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom alleviates; Continue to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom all disappears, and follows up a case by regular visits to and does not recur, and thoroughly cures.
5, certain is practised, man, 26 years old, profession, people from Kweiyang, Guizhou.Patient occurs swallowing discomfort, companion's itching throat, pharyngalgia, cough, and the symptoms such as hoarseness, can only eat spoon meat, to our hospital, are diagnosed as esophageal carcinoma by checking.Implement Post operation and take 2 courses for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom takes a turn for the better; After continuing to take 1 course for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom disappears, wound healing, and health is fully recovered, and follows up a case by regular visits to and does not recur.
6, certain is shut out, female, 32 years old, performer, recluse in Guangdong.Without obvious inducement, patient occurs that feed is choked with sobs, feed is dry, hard food time obvious, can enter soft diet liquid food, without acid regurgitation, vomiting, without heating, spits blood and melena, and it is invalid after Supporting Therapy March to the ill to give with " esophagitis " in hospital, and rear feed is choked with sobs to feel and comparatively before increased the weight of.Go to a doctor at local hospital, be diagnosed as esophageal carcinoma.Postoperative take 3 courses for the treatment of of Chinese medicine preparation of the present invention after, above-mentioned symptom takes a turn for the better; Continue to take 1 course for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom disappears, and health is fully recovered, and follows up a case by regular visits to and does not recur, thoroughly cure.
Claims (5)
1. for a Chinese medicine preparation for esophageal carcinoma post-operative recovery, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 33-65 part Fructus Averrhoae Carambolae 31-63 part Chinese alpine rush 31-63 part Herba Ixeritis Denticulatae 29-61 part
Herba polygoni senticosi 29-53 part Aster oreophilus Franch 28-52 part Fructus Canarii Pimelae 27-51 part Fructus polygoni tinctorii 23-47 part
Herba Physalis pubescentis 21-45 part Radix Ardisiae Crispae 21-45 part Fructus Forsythiae 18-38 part Nux Pruni pseudocerasi 18-38 part
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 17-37 part Rhizoma Polygonati Verticillati 15-35 Fen Caulis et folium vitis thunbergii 13-33 part Borneolum Syntheticum 11-31 part.
2. a kind of Chinese medicine preparation for esophageal carcinoma post-operative recovery according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 57 parts of Fructus Averrhoae Carambolaes 55 portions of Chinese alpine rush 55 parts of Herba Ixeritis Denticulataes 53 parts
Herba polygoni senticosi 47 parts of Aster oreophilus Franch 46 portions of Fructus Canarii Pimelaes 45 parts of Fructus polygoni tinctorii 41 parts
Herba Physalis pubescentis 39 parts of Radix Ardisiae Crispaes 39 parts of Fructus Forsythiaes 33 parts of Nux Pruni pseudocerasis 33 parts
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 32 parts of Rhizoma Polygonati Verticillati 30 Fen Caulis et folium vitis thunbergii 28 parts of Borneolum Syntheticums 26 parts.
3. a kind of Chinese medicine preparation for esophageal carcinoma post-operative recovery according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 49 parts of Fructus Averrhoae Carambolaes 47 portions of Chinese alpine rush 47 parts of Herba Ixeritis Denticulataes 45 parts
Herba polygoni senticosi 41 parts of Aster oreophilus Franch 40 portions of Fructus Canarii Pimelaes 39 parts of Fructus polygoni tinctorii 35 parts
Herba Physalis pubescentis 33 parts of Radix Ardisiae Crispaes 33 parts of Fructus Forsythiaes 28 parts of Nux Pruni pseudocerasis 28 parts
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 27 parts of Rhizoma Polygonati Verticillati 25 Fen Caulis et folium vitis thunbergii 23 parts of Borneolum Syntheticums 21 parts.
4. a kind of Chinese medicine preparation for esophageal carcinoma post-operative recovery according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Scutellariae indicae 41 parts of Fructus Averrhoae Carambolaes 39 portions of Chinese alpine rush 39 parts of Herba Ixeritis Denticulataes 37 parts
Herba polygoni senticosi 35 parts of Aster oreophilus Franch 34 portions of Fructus Canarii Pimelaes 33 parts of Fructus polygoni tinctorii 29 parts
Herba Physalis pubescentis 27 parts of Radix Ardisiae Crispaes 27 parts of Fructus Forsythiaes 23 parts of Nux Pruni pseudocerasis 23 parts
Camellia sinensis O. Ktze. Var. macrophylla Sieb. 22 parts of Rhizoma Polygonati Verticillati 20 Fen Caulis et folium vitis thunbergii 18 parts of Borneolum Syntheticums 16 parts.
5. a preparation method for the Chinese medicine preparation for esophageal carcinoma post-operative recovery as described in claim 1-4, is characterized in that: comprise following processing step:
(1) by Herba Scutellariae indicae with Herba Physalis pubescentis is cleaned, put into container, smash to pieces, stay juice for subsequent use;
(2) by Fructus Averrhoae Carambolae, Chinese alpine rush, Herba Ixeritis Denticulatae, Aster oreophilus Franch, Fructus Canarii Pimelae, Fructus polygoni tinctorii, Radix Ardisiae Crispae, Fructus Forsythiae, Nux Pruni pseudocerasi, Camellia sinensis O. Ktze. Var. macrophylla Sieb. with Caulis et folium vitis thunbergii puts into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge extractive liquid, filters, filtrate is condensed into the thick paste of relative density 1.10 ~ 1.15 at 60 DEG C, for subsequent use;
(3) Herba polygoni senticosi and Rhizoma Polygonati Verticillati are dried, grind into powder, cross 120 order fine powders, for subsequent use;
(4) ethanol of Borneolum Syntheticum 5ml90% is melted, obtain solution for standby;
(5) fine powder that thick paste juice obtained for step (1), step (2) obtained, step (3) are obtained and the solution mixing that step (4) obtains, make tablet, be the described Chinese medicine preparation for the postoperative mouth care of esophageal carcinoma.
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| CN101683499A (en) * | 2008-09-24 | 2010-03-31 | 王孙勇 | Cancer curing capsule |
| CN103656088A (en) * | 2013-12-11 | 2014-03-26 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicinal powder for treating dental ulcer |
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| CN101683499A (en) * | 2008-09-24 | 2010-03-31 | 王孙勇 | Cancer curing capsule |
| CN103656088A (en) * | 2013-12-11 | 2014-03-26 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicinal powder for treating dental ulcer |
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| 复方中药外治法治疗复发性口疮80例临床观察;李文胜等;《四川中医》;20090430;第27卷(第04期);第100页第1栏第4段至第2栏第1段 * |
| 食管癌根治术后口腔炎发生的原因及对策;范宁;《职业与健康》;20060831;第22卷(第16期);第1320页第1栏第2段至第1321页第2栏第3段 * |
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