CN106110029A - A kind of external-applied ointment treating skin allergy and preparation method - Google Patents
A kind of external-applied ointment treating skin allergy and preparation method Download PDFInfo
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- CN106110029A CN106110029A CN201610624907.4A CN201610624907A CN106110029A CN 106110029 A CN106110029 A CN 106110029A CN 201610624907 A CN201610624907 A CN 201610624907A CN 106110029 A CN106110029 A CN 106110029A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/76—Salicaceae (Willow family), e.g. poplar
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of external-applied ointment treating skin allergy and preparation method, belong to the field of Chinese medicines；The raw material of external-applied ointment effective ingredient of the present invention forms and parts by weight are: Herba Polygoni hydropiperis, Folium Rumicis Japonici, attached column flower, Folium Baeckeae, Herba Saginae Japonicae, Herba Arthraxonis Hispidi, Folium Pruni, Lemmaphyllum microphullum Presl, Adeps Bovis seu Bubali, Radix Rumicis Patientiae, Herba Eriae Panneae, Radix Carpesii, Folium Persicae, Salix chienii Cheng, dried tuber and Flos Campsis；The selected Chinese crude drug prescription with effects such as clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, dispelling wind for relieving itching, promoting tissue regeneration and ulcer healing, cooling blood for hemostasis of external-applied ointment of the present invention is concocted, all medicines are harmonious and can directly arrive diseased region, for treatment skin allergy, there is the advantages such as instant effect, cure rate is high, have no side effect, safe ready, curative effect are lasting, be suitable to the popularization and application of skin allergy clinical treatment and nursing.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of external-applied ointment treating skin allergy and preparation method.
Background technology
Skin allergy is the most common a kind of allergy form, has the people of 20% to have phenomena of cutaneous irritation.Skin allergy also known as
For sensitive skin.Saying from medical angle, skin allergy is primarily referred to as when skin is made up by various stimulations such as untoward reaction
Product, chemicals, pollen, some food, the air etc. of pollution, cause skin occur red and swollen, itch, peel and allergic dermatitis
Deng abnormal phenomena.Sensitivity skin can be described as a kind of non-persistent skin, is a kind of skin being at any time in high alert.
Its nursing to give special heed to.
Skin allergy cardinal symptom is to itch, and is likely to form a scab with the dry bits of redness, blister or focus and ooze out simultaneously
The symptoms such as liquefaction, the shape of these focuses has nothing in common with each other with size, other skin allergy symptoms also include sneeze, runny nose,
The skin symptoms such as tearful eyes, erythra, airway obstruction.
The when of skin allergy morbidity, general skin surface has crimson, and that touches has pain, and some skin allergy there is also
Slight desquamation, even has breach, the serious skin having influence on patient so that skin tarnishes, and has influence on appearance.Skin
Allergy can destroy the immune system of health sometimes so that antibacterial etc. other lure the cause of disease this take advantage of the occasion to invade health, induce one
A little complication, some complication is the most serious, if allergy is to occur at throat, laryngopharynx swelling and pain occurs, may draw
Send out death by suffocation. skin allergy is sometimes along with violent pruritis, and patient lies awake all night, sleep quality significantly under
Fall, the life on daytime also can be greatly affected, and easily allows patient become impetuous, can not carry out orthobiosis.Skin allergy
Make the image of patient impaired, and because suffer from slight illness, in the face of the eye of other people difference, a lot of patients become not from
Letter, being far from the crowd gradually, lack exchange for a long time, the great pressure of psychological endurance so that psychological disease easily occurs in patient
Sick.
Various for treating the medicament categories of skin allergy, there are Western medicine class, Chinese patent medicine class etc., these existing treatment skins
The defect of the medicine of allergy is can not thoroughly to effect a radical cure skin allergy disease, suffers from and often showing effect at skin allergy, to the health of patient
Bring infringement and financial burden.To this end, we are badly in need of developing external-applied ointment that a kind of safety has no side effect to help patient to break away from
The misery that skin allergy brings.
Summary of the invention
The invention provides a kind of external-applied ointment treating skin allergy and preparation method；The selected tool of external-applied ointment of the present invention
The Chinese crude drug prescription having the effects such as clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, dispelling wind for relieving itching, promoting tissue regeneration and ulcer healing, cooling blood for hemostasis is concocted, and all medicines are harmonious
Can directly arrive diseased region, for treatment skin allergy have instant effect, cure rate is high, have no side effect, safe ready, treatment
The advantages such as effect is lasting, are suitable to the popularization and application of skin allergy clinical treatment and nursing.
For achieving the above object, technical scheme is implemented as follows:
A kind of external-applied ointment treating skin allergy, makes raw material composition and the weight portion of described external-applied ointment effective ingredient
Number is:
Make described external-applied ointment effective ingredient raw material composition and parts by weight be:
Make described external-applied ointment effective ingredient raw material composition and parts by weight be:
Make described external-applied ointment effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of external-applied ointment treating skin allergy, comprises the following steps that:
(1) Herba Polygoni hydropiperis, Folium Baeckeae, Herba Arthraxonis Hispidi, Folium Pruni, Radix Carpesii, Folium Persicae, Salix chienii Cheng and dried tuber are put in container, add distillation
Water boil extracts 3 times, adds 8-10 times amount distilled water immersion first 4-5 hour, and heated and boiled is extracted 3-4 hour；Second time adds 8-
10 times amount distilled water heated and boiled are extracted 2-3 hour, and third time adds 6-8 times amount distilled water heated and boiled and extracts 1-2 hour, merges
Extracting solution, filters, obtains filtrate, be condensed into dry extract standby.It is 90% alcoholic solution that dry extract adds volumetric concentration, stands,
Being extracted by supernatant, the extractum precipitated is standby；
(2) Folium Rumicis Japonici, attached column flower, Herba Saginae Japonicae, Adeps Bovis seu Bubali and Herba Eriae Panneae are twisted respectively juice, filter impurity, stay juice, standby；
(3) by Lemmaphyllum microphullum Presl and Radix Rumicis Patientiae microwave drying, grind into powder, obtained the fine powder of 140 mesh, standby；
(4) Flos Campsis is immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pour in pot, slow fire parch, after cooling,
Smash to pieces and grind into powder, obtained the fine powder of 160 mesh, standby；
(5) step (1)-extractum of (4) gained, juice and fine powder are mixed, after adding vaseline, be prepared as externally-applied ointment
Agent product, is the external-applied ointment of described treatment skin allergy.
The property of medicine of Chinese medicine used by the present invention is as follows:
Herba Polygoni hydropiperis: acrid in the mouth, hardship, property is put down；Return spleen, stomach, large intestine channel.The stagnant removing dampness of row, dissipating blood stasis stops blooding, dispelling wind for relieving itching, removing toxic substances.Main wet
Stagnant internal resistance, the vexed stomachache of gastral cavity, have loose bowels, dysentery, infantile malnutrition, metrorrhagia, amenorrhea due to stagnation of blood dysmenorrhea, traumatic injury, rheumatic arthralgia, have blood in stool,
Traumatic hemorrhage, skin pruritus, eczema, rubella, tinea pedis, carbuncle, venom.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " profit
Wet disappear stagnant, killing parasites for relieving itching.Control bacillary dysentery, enteritis, rheumatalgia, skin eczema.”
Folium Rumicis Japonici: sweet in the mouth, cold in nature.Cooling blood for hemostasis, relieving constipation, removing toxic substances and promoting subsidence of swelling, killing parasites for relieving itching.Main discharging fresh blood stool, constipation, children's
Infantile malnutrition ulcerative carbuncle toxic swelling, scabies." Guizhou side among the people medicine collection " carries: " external disappears and hinders swollen sore." modern medicine study confirmation, Folium Rumicis Japonici
Decoct in vitro anthrax is planted bacillus and diphtheria corynebacterium has obvious inhibiting effect, to staphylococcus aureus, group B streptococcus,
Escherichia coli, Bacillus typhi and dysentery bacterium etc. also have certain antibacterial action.
Attached column flower: mildly bitter flavor, pungent, cool in nature.Heat-clearing and toxic substances removing, dampness removing is antipruritic, reducing swelling and alleviating pain.Main dysentery, skin infection, eczema, skin
Skin pruritus, caterpillar stabs, traumatic injury.
Folium Baeckeae: bitter in the mouth, pungent, cool in nature.Blood-activating analgetic, heat clearing away unit of weight measurement, about six liang poison, inducing diuresis for treating stranguria syndrome, killing parasites for relieving itching.Main traumatic injury, tripe is hard
Change, diarrhea of heat type, pyretic stranguria, dysuria, pudendal pruritus, tinea pedis, eczema, skin pruritus, scabies, burn due to hot liquid or fire, worm venom." in Guangxi
Medicine will " carry: " there is diuresis promoting effect.Control bladder heat, dysuria, pudendal pruritus, skin steam.Decoct washing skin rotten itch, eczema；
Leaf, smashes deposited, controls Scolopendra wound, branch and leaf, steam oil, controls skin ulcer leprosy etc..”
Herba Saginae Japonicae: bitter in the mouth, pungent, cool in nature；Return liver, stomach warp.Removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching.Main dermatitis rhus, tinea alba, eczema, red
Poison, scrofula, innominate toxic swelling, venom, nasal sinusitis, caries pain, internal traumatic injury." Guizhou side among the people medicine collection " carries: " carbuncle is controlled in external
Swollen, sore；Suck and control dental caries.”
Herba Arthraxonis Hispidi: bitter in the mouth, property is put down.Relieving cough and relieving asthma, parasite killing detoxifies.Main chronic cough is panted, hepatitis, pharyngolaryngitis, stomatitis, rhinitis,
Lymphadenitis, mastitis, skin infection scabies." herbal classic " carries: " main chronic cough dyspnea due to adverse flow of lung-QI is inverse, trembles with fear for a long time, palpitation with fear, crusted scabies, and white bald infections gas kills
Skin small worm.”
Folium Pruni: acrid in the mouth, hardship, slightly cool in nature；Return liver, spleen channel.Expelling wind and removing dampness, improving eyesight.Main edema, skin pruritus, the many tear of mesh disease,
Ulcerative carbuncle scrofula." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " apply big malignant boil.”
Lemmaphyllum microphullum Presl: acrid in the mouth, cool, the micro-hardship of property；Return lung, liver, stomach warp.Clearing away lung-heat to relieve cough, cooling blood for hemostasis, heat-clearing and toxic substances removing.Main lung-heat
Cough, lung abscess, spitting of blood, spit blood, epistaxis, hematuria, have blood in stool, metrorrhagia, laryngopharynx swelling and pain, parotitis, dysentery, scrofula, ulcerative carbuncle toxic swelling, skin
Skin pruritus due to damp pathogen, acute toothache, rheumatic ostalgia.Supplement to the Herbal carries: " tinea pedis swells for main carbuncle, rubella.Smash deposited it, also boil soup and wash swollen
Place.”
Adeps Bovis seu Bubali: acrid in the mouth, micro-hardship, cool in nature.Induce sweat, regulate the flow of vital energy, clearing away summer-heat, dampness removing.Main cold, fever, heatstroke, chest and diaphragm distension, stomachache
Vomiting and diarrhoea dysentery, jaundice, edema, leukorrhagia, children's's cellulitis is long-pending, and measles, skin pruritus, skin infection swells and ache, traumatic injury.
Radix Rumicis Patientiae: bitter in the mouth, acid, cold in nature.Heat-clearing and toxic substances removing, hemostasia and detumescence, relieving constipation, parasite killing.Main haematemesis, epistaxis, have blood in stool, collapse
Leakage, leucorrhea with red and white discharge, purpura, dysentery, hepatitis, constipation, dysuria, ulcerative carbuncle toxic swelling, scabies, traumatic injury, burn and scald.
" Shaanxi Chinese herbal medicine " carries: " promoting blood circulation to remove blood stasis, hemostasis, heat-clearing and toxic substances removing, loosening bowel to relieve constipation.Control traumatic injury, internal hemorrhage, purpura disease, Tang Huo
Wound, fester skin ulcer, tinea, appendicitis, chronic enteritis, constipation.”
Herba Eriae Panneae: bitter in the mouth, cool in nature；Return lung, heart channel.Eliminating stasis to stop pain, heat-clearing and toxic substances removing.Main lumbago and skelalgia, traumatic injury, fracture, carbuncle
Furuncle swells, burn and scald, drug intoxication." choosing of Simao, Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, synthetism.Control traumatic injury to damage
Wound, fracture, ulcerative carbuncle furuncle and phyma, burn and scald, drug intoxication.”
Radix Carpesii: bitter in the mouth, pungent, cold in nature；Return liver, lung meridian.Heat clearing away, reduces phlegm, removing toxic substances, parasite killing, removing blood stasis with potent drugs, hemostasis.Main tonsillitis, larynx
Numbness, anxious chronic infantile convulsion, toothache, furuncle swelling toxin, hemorrhoid complicated by anal fistula, itchy skin eruption, venom, malnutrition due to parasitic infestation, abdominal mass due to blood stasis, spit blood, epistaxis, stranguria with blood, wound
Hinder hemorrhage.Tang Materia Medica carries: " main removing blood stasis, granulation promoting, quench the thirst, diuresis, kills three worms.Except all poison swell furuncle, fistula hemorrhoid, penetrate in incised wound.
The more than person of itching over the body urticaria, that wipes is vertical own.”
Folium Persicae: bitter in the mouth, pungent, property is put down；Return spleen, kidney channel.Expelling wind and clearing away heat, parasite killing.Main wind syndrome of head, headache, migratory arthralgia, malaria, eczema,
Skin infection, tinea skin ulcer." Guizhou side among the people medicine collection " carries: " to boil water wash, dispelling the wind and dampness pathogens；External subduing inflammation.”
Salix chienii Cheng: acrid in the mouth, hardship, cold in nature.Heat-clearing and toxic substances removing, dispelling wind for relieving itching, pain relieving.Main cold, fever, laryngopharynx swelling and pain, skin scabies
Itch, cystitis, urethritis, traumatic pain.
Dried tuber: bitter in the mouth, pungent, cool in nature；Return liver, lung meridian.Activating QI to alleviate the depression, dispelling wind for relieving itching, wide born of the same parents' profit expectorant.Master is uncomfortable in chest does not relaxes, wind
Rash pruritus, carbuncle is with toxic swelling." carrying out rock book on Chinese herbal medicine " carries: " control skin pruritus, all over the raw wind of body.”
Flos Campsis: sour in the mouth, cold nature；Return Liver Channel.Clearing away heat and cooling blood, blood stasis-eliminating and stagnation-dissipating, dispelling wind for relieving itching.Main amenorrhea due to stagnation of blood, dysmenorrhea,
Lump in the abdomen, metrorrhagia and metrostaxis, heat in blood pruritus due to wind pathogen, skin ulcer scabies falls into rash, rosacea." detailed outline " carry: " Ling Leihua and root, sweet acid and tremble with fear, stem and leaf band
Hardship, promoting the circulation of blood divides, the fire second of the three ten-day periods of the hot season of dehematizing, therefore the card of all diseases of main product breast metrorrhagia and blood hot air wind producing is also." modern medicine study confirmation, insult
Apigenin during clouds are spent has moderate spasmolysis, also antiulcer action to smooth muscle, and cupreol has hypercholesterolemia, stops
Cough, anticancer, antiinflammatory etc. acts on.
The present invention compared with prior art, has the advantages that
External-applied ointment of the present invention is selected has clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, dispelling wind for relieving itching, promoting tissue regeneration and ulcer healing, cooling blood for hemostasis etc.
The Chinese crude drug prescription of effect is concocted, and all medicines are harmonious and can directly arrive diseased region, and treatment skin allergy is had to instant effect, controls
The advantages such as more rate is high, have no side effect, safe ready, curative effect are lasting, the popularization being suitable to skin allergy clinical treatment and nursing should
With.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of external-applied ointment effective ingredient of the present invention forms and weight is:
The processing step of external-applied ointment preparation method of the present invention is:
(1) Herba Polygoni hydropiperis, Folium Baeckeae, Herba Arthraxonis Hispidi, Folium Pruni, Radix Carpesii, Folium Persicae, Salix chienii Cheng and dried tuber are put in container, add distillation
Water boil extracts 3 times, adds 8-10 times amount distilled water immersion first 4-5 hour, and heated and boiled is extracted 3-4 hour；Second time adds 8-
10 times amount distilled water heated and boiled are extracted 2-3 hour, and third time adds 6-8 times amount distilled water heated and boiled and extracts 1-2 hour, merges
Extracting solution, filters, obtains filtrate, be condensed into dry extract standby.It is 90% alcoholic solution that dry extract adds volumetric concentration, stands,
Being extracted by supernatant, the extractum precipitated is standby；
(2) Folium Rumicis Japonici, attached column flower, Herba Saginae Japonicae, Adeps Bovis seu Bubali and Herba Eriae Panneae are twisted respectively juice, filter impurity, stay juice, standby；
(3) by Lemmaphyllum microphullum Presl and Radix Rumicis Patientiae microwave drying, grind into powder, obtained the fine powder of 140 mesh, standby；
(4) Flos Campsis is immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pour in pot, slow fire parch, after cooling,
Smash to pieces and grind into powder, obtained the fine powder of 160 mesh, standby；
(5) step (1)-extractum of (4) gained, juice and fine powder are mixed, after adding vaseline, be prepared as externally-applied ointment
Agent product, is the external-applied ointment of described treatment skin allergy.
Usage and dosage: three times a day, each 3-6g, uniform application is in affected part.Within 6 days, it is a course for the treatment of, usual 1-2 the course for the treatment of
Onset.
Embodiment 2
The raw material of external-applied ointment effective ingredient of the present invention forms and weight is:
The external-applied ointment preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of external-applied ointment effective ingredient of the present invention forms and weight is:
The external-applied ointment preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of external-applied ointment effective ingredient of the present invention forms and weight is:
The external-applied ointment preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
Selecting the skin allergy patient 140 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group
70 examples, wherein male 35 example, women 35 example, age 10-70 year, 42.8 years old mean age, course of disease 1-20.Matched group 70 example,
Wherein male 35 example, women 35 example, age 10-69 year, 43 years old mean age, course of disease 1-20；The course of disease of two groups of cases, symptom
Light and heavy degree is basically identical, without significant difference, has comparability.
2, medicament selection:
Treatment group patient smears external-applied ointment of the present invention, and three times a day, each 3-6g, 6 days is a course for the treatment of, generally to adult
1-2 the course for the treatment of is effective, and pertinacious disease needs 3-4 the course for the treatment of.
Matched group smears betamethasone neomycin emulsifiable paste, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: face decortication, cervical region flushing, high dermis can have edema, bubble sample edema, dermatorrhagia speckle, special official report body
Matter, skin abrasion, corse sweat pore, systemic anaphylaxis, skin have the transference cures such as pruritus scratch.
(2) effective: above-mentioned symptom has been alleviated.
(3) invalid: disease is unchanged.
4, result:
Smear in the treatment group of external-applied ointment of the present invention, cure 49 examples, effective 18 examples, invalid 3 examples, cure rate 70%, always
Effective percentage 95.7%.
Matched group is cured 12 examples, effective 20 examples, invalid 38 examples, cure rate 17.1%, total effective rate 45.7%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Hao, female, 20 years old, student, Xiamen of Fujian Province people.It is block that entire patient's skin is dispersed in the limitation that differs in size
Edema welt, little to the grain of rice, greatly to hand size, slightly above surrounding skin, very itch incomparable.To local hospital dermatological treatment
Unsatisfactory curative effect, and have and increase the weight of trend.The most to our hospital, it is diagnosed as skin allergy on inspection.Smear external-applied ointment of the present invention 1
After the course for the treatment of, above-mentioned symptom takes a turn for the better；Continuing to smear 2 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom disappears, and follows up a case by regular visits to the most multiple
Send out.
2, Wang, female, 27 years old, white collar, people from Guangan, Sichuan.There is face redness, cervical region flushing, scabies in patient after eating up seafood
The symptom such as itch, deliver to me through household and institute go to a doctor, be skin allergy by diagnosis.After smear 1 course for the treatment of of external-applied ointment of the present invention,
Above-mentioned symptom takes a turn for the better；Continuing to smear 1 course for the treatment of of external-applied ointment of the present invention, above-mentioned symptom is wholly absent, and follows up a case by regular visits to not recur.
3, field, man, 40 years old, manager, Guizhou Liu Panshui people.Patient, because of being not acclimatized of going on business to strange land, causes going out on the face
The little red pimple now differed in size, to our hospital, it is diagnosed as skin allergy on inspection.After smear external-applied ointment of the present invention
1 course for the treatment of, little red pimple reduces；Continuing to smear 1 course for the treatment of of external-applied ointment of the present invention, little red pimple disappears, follows up a case by regular visits to not recur.
4, virgin certain, man, 30 years old, security personnel, people from Nantong.Patient arrives pharmacy voluntarily and buys eye drop because of ocular pruritis, and second
Find nose both sides skin banding erythema when it morning rises, have pruritis.The most to our hospital, it is diagnosed as contact dermatitis.Give
After smearing 2 courses for the treatment of of external-applied ointment of the present invention, skin allergy symptom alleviates, and picks body；Continue to smear external-applied ointment 1 of the present invention
The individual course for the treatment of, skin allergy symptom is wholly absent, and follows up a case by regular visits to not recur.
5, willow, man, 35 years old, business personnel, people from Yibin, Sichuan.Patient continues within 2 weeks, occur that trunk, Head And Face, extremity are dispersed in
Property erythema, erythema flaring is big, merge and extend to whole body, conscious slight pruritus.To our hospital, it is diagnosed as skin mistake on inspection
Quick.After smearing 1 course for the treatment of of external-applied ointment of the present invention, above-mentioned symptom takes a turn for the better；Continue to smear 1 course for the treatment of of external-applied ointment of the present invention
After, above-mentioned symptom all disappears, and follows up a case by regular visits to not recur.
6, poplar, female, 60 years old, peasant, people from Yichang.Patient plays erythema companion's scabies for 1 year inside preabdomen, both thighs
Itching, buy " PIYANPINGSHUANG " by oneself and be coated with outward, pruritus slightly alleviates, but skin lesion expanded range.The most to our hospital, it is diagnosed as skin on inspection
Allergy.Smearing 2 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom takes a turn for the better；Continue to smear external-applied ointment of the present invention 1 treatment
Journey, above-mentioned symptom is wholly absent, and health is fully recovered, and follows up a case by regular visits to not recur.
Claims (5)
1. the external-applied ointment treating skin allergy, it is characterised in that: make the raw material group of described external-applied ointment effective ingredient
Become and parts by weight be:
Herba Polygoni hydropiperis 64-84 part Folium Rumicis Japonici 62-82 part attached column flower 60-80 part Folium Baeckeae 57-77 part
Herba Saginae Japonicae 54-74 part Herba Arthraxonis Hispidi 52-72 part Folium Pruni 47-67 part Lemmaphyllum microphullum Presl 42-62 part
Adeps Bovis seu Bubali 37-57 part Radix Rumicis Patientiae 32-52 part Herba Eriae Panneae 27-47 part Radix Carpesii 22-42 part
Folium Persicae 17-37 part Salix chienii Cheng 12-32 part dried tuber 7-27 part Flos Campsis 7-19 part.
A kind of external-applied ointment treating skin allergy the most according to claim 1, it is characterised in that: make described medicine for external use
The raw material of cream effective ingredient forms and parts by weight are:
Herba Polygoni hydropiperis 77 parts of attached columns of 79 parts of Folium Rumicis Japonici spend 75 parts of Folium Baeckeaes 72 parts
69 parts of Herba Arthraxonis Hispidis of Herba Saginae Japonicae, 62 parts of Lemmaphyllum microphullum Presls of 67 parts of Folium Pruni 57 parts
52 parts of Radix Rumicis Patientiae of Adeps Bovis seu Bubali, 42 parts of Radix Carpesiis of 47 parts of Herba Eriae Panneae 37 parts
32 parts of Salix chienii Cheng of Folium Persicae, 22 parts of Flos Campsiss of 27 portions of dried tubers 16 parts.
A kind of external-applied ointment treating skin allergy the most according to claim 1, it is characterised in that: make described medicine for external use
The raw material of cream effective ingredient forms and parts by weight are:
Herba Polygoni hydropiperis 72 parts of attached columns of 74 parts of Folium Rumicis Japonici spend 70 parts of Folium Baeckeaes 67 parts
64 parts of Herba Arthraxonis Hispidis of Herba Saginae Japonicae, 57 parts of Lemmaphyllum microphullum Presls of 62 parts of Folium Pruni 52 parts
47 parts of Radix Rumicis Patientiae of Adeps Bovis seu Bubali, 37 parts of Radix Carpesiis of 42 parts of Herba Eriae Panneae 32 parts
27 parts of Salix chienii Cheng of Folium Persicae, 17 parts of Flos Campsiss of 22 portions of dried tubers 13 parts.
A kind of external-applied ointment treating skin allergy the most according to claim 1, it is characterised in that: make described medicine for external use
The raw material of cream effective ingredient forms and parts by weight are:
Herba Polygoni hydropiperis 67 parts of attached columns of 69 parts of Folium Rumicis Japonici spend 65 parts of Folium Baeckeaes 62 parts
59 parts of Herba Arthraxonis Hispidis of Herba Saginae Japonicae, 52 parts of Lemmaphyllum microphullum Presls of 57 parts of Folium Pruni 47 parts
42 parts of Radix Rumicis Patientiae of Adeps Bovis seu Bubali, 32 parts of Radix Carpesiis of 37 parts of Herba Eriae Panneae 27 parts
22 parts of Salix chienii Cheng of Folium Persicae, 12 parts of Flos Campsiss of 17 portions of dried tubers 10 parts.
5. a preparation method for the external-applied ointment of the treatment skin allergy as described in any one of claim 1-4, its feature exists
In: comprise the following steps that:
(1) Herba Polygoni hydropiperis, Folium Baeckeae, Herba Arthraxonis Hispidi, Folium Pruni, Radix Carpesii, Folium Persicae, Salix chienii Cheng and dried tuber are put in container, add distillation decocting in water
Boiling is extracted 3 times, adds 8-10 times amount distilled water immersion first 4-5 hour, and heated and boiled is extracted 3-4 hour；Second time adds 8-10 times
Amount distilled water heated and boiled is extracted 2-3 hour, and third time adds 6-8 times amount distilled water heated and boiled and extracts 1-2 hour, united extraction
Liquid, filters, obtains filtrate, be condensed into dry extract standby；It is 90% alcoholic solution that dry extract adds volumetric concentration, stands, by supernatant
Liquid extracts, and the extractum precipitated is standby；
(2) Folium Rumicis Japonici, attached column flower, Herba Saginae Japonicae, Adeps Bovis seu Bubali and Herba Eriae Panneae are twisted respectively juice, filter impurity, stay juice, standby；
(3) by Lemmaphyllum microphullum Presl and Radix Rumicis Patientiae microwave drying, grind into powder, obtained the fine powder of 140 mesh, standby；
(4) Flos Campsis is immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pour in pot, slow fire parch, after cooling, smash to pieces
Grind into powder, obtained the fine powder of 160 mesh, standby；
(5) step (1)-extractum of (4) gained, juice and fine powder are mixed, after adding vaseline, be prepared as externally-applied soft ointment and produce
Product, are the external-applied ointment of described treatment skin allergy.
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| CN201610624907.4A CN106110029A (en) | 2016-07-30 | 2016-07-30 | A kind of external-applied ointment treating skin allergy and preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111714556A (en) * | 2020-08-09 | 2020-09-29 | 仲崇允 | A topical Chinese medicinal preparation for treating dermatoses |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103356890A (en) * | 2013-07-31 | 2013-10-23 | 徐冰娜 | Externally-applied traditional Chinese medicinal preparation for treating skin allergy and pruritus, and preparation method thereof |
| CN104840580A (en) * | 2015-04-30 | 2015-08-19 | 济南骄泰信息技术有限公司 | Traditional Chinese medicine for skin allergy nursing |
-
2016
- 2016-07-30 CN CN201610624907.4A patent/CN106110029A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103356890A (en) * | 2013-07-31 | 2013-10-23 | 徐冰娜 | Externally-applied traditional Chinese medicinal preparation for treating skin allergy and pruritus, and preparation method thereof |
| CN104840580A (en) * | 2015-04-30 | 2015-08-19 | 济南骄泰信息技术有限公司 | Traditional Chinese medicine for skin allergy nursing |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111714556A (en) * | 2020-08-09 | 2020-09-29 | 仲崇允 | A topical Chinese medicinal preparation for treating dermatoses |
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