CN107126518A

CN107126518A - A kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus

Info

Publication number: CN107126518A
Application number: CN201710273617.4A
Authority: CN
Inventors: 崔丛丛
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-04-25
Filing date: 2017-04-25
Publication date: 2017-09-05

Abstract

A kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus, its raw material composition and parts by weight are：12 17 parts of great burdock achene, 7 12 parts of Asian puccoon, 49 parts of indian skullcap herb with root, 15 20 parts of eupatorium, 10 15 parts of canarium pimela, 8 12 parts of the root of kudzu vine, 25 parts of cacumen biotae, 37 parts of the tuber of dwarf lilyturf, 11 14 parts of dandelion, 9 15 parts of folium isatidis, 36 parts of lotus leaf, 8 13 parts of peach branch, 35 parts of cherry stone, 13 parts of cape jasmine, 5 10 parts of aloe, 36 parts of balsam pear, 8 13 parts of Herba Andrographitis, 35 parts of HERBA CIRSII, 11 15 parts of caulis trachelospermi, 5 10 parts of caulis lonicerae, 25 parts of Momordica grosvenori, 49 parts of rush, 12 20 parts of Sagina subulata, 10 16 parts of Radix zanthoxyli, 38 parts of indigo naturalis, 5 12 parts of the coptis, 5 10 parts of lophatherum gracile, 13 16 parts of pseudo-ginseng, 3 10 parts of moutan bark.

Description

A kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus

Technical field

The invention belongs to pharmaceutical technology field, it is related to a kind of Chinese medicine composition, and in particular to it is postoperative that one kind is used for cancer of the esophagus The Chinese medicine composition of oral care.

Background technology

The cancer of the esophagus is common tumor in digestive tract, and the whole world there are about 300,000 people and dies from the cancer of the esophagus every year.Its incidence of disease and dead Wang Shuai various countries are widely different.China is one of Esophageal Cancer area in the world, and die of illness about 150,000 people per annual.Man is more than Female, age of onset is more more than 40 years old.The typical symptom of the cancer of the esophagus is progressive dyscatabrosis, before this food of difficult dry throat, after But semiliquid diet, last water and saliva can not be swallowed.

Cancer of the esophagus early symptom often not substantially, but may have different degrees of uncomfortable sensation when swallowing thick and stiff food, is wrapped Include to swallow and sample, acupuncture sample or drawing friction sample pain are burnt after food choking feeling, breastbone.Food has stagnation to feel by slow Or foreign body sensation.Stalk choke is stagnated sense and disappeared usually through alleviation after water is swallowed.Weight, makes slow progress when light during symptom.Advanced esophageal carcinoma Typical symptom is progressive dyscatabrosis, before this food of difficult dry throat, is then semiliquid diet, and last water and saliva are not yet It can swallow.Mucoid phlegm often is told, the secretion of saliva and oesophagus for hypopharynx.Patient gradually becomes thin, is dehydrated, powerless.Continue chest Pain or backache are expressed as late period symptom, and cancer has been invaded outside oesophagus and organized.

After cancerous swelling blocks caused inflammation oedema transient remission, or part cancerous swelling comes off, obstruction can temporarily subtract Gently, constant error thinks that sb.'s illness took a favorable turn.If cancerous swelling invades recurrent nerve, hoarseness may occur in which；If oppressing cervical sympathetic ganglia, it can produce Raw Horner syndromes；If invading trachea-bronchial epithelial cell, oesophagus, tracheae or bronchial fistula can be formed, when there is swallowing water or food Acutely choke and cough, and occur infection in respiratory system.Finally there are cachectic states.If there are the Organ relative weights such as liver, brain, Huang may occur in which The states such as subcutaneous ulcer, seroperitoneum, stupor.

The method for the treatment of cancer of the esophagus is mainly operative treatment at present.Burst in after Thoracic esophageal carcinoma and radiotherapy it is possible that oral cavity Ulcer symptom, in cyclic recurrence.Patient with esophageal carcinoma is postoperative, because the state of an illness needs, there is the fasting phase.During this period, due to operation plane Wound, patient's resistance declines, and adding patient with esophageal carcinoma needs fasting for solids and liquids, salivary secretion reduction, more reduces the antibacterial energy in oral cavity Power, patient with esophageal carcinoma is not if noted oral hygiene, and intraoral bacterium is possible to as saliva enters esophagus, and in wound location Breeding is stopped, wound infection is caused.If using stomach tube in patient's treatment, rear wall is swallowed by the dead angle as cleaning, a variety of factors Postoperative patient with esophageal carcinoma will be caused to occur canker sore, and then influence postoperative rehabilitation.With continuing to develop for modern medicine, art After nurse and also gradually paid attention to, after being nursed, the recovery that correct nursing is carried out to patient affected part for disease will have It is significant.

The content of the invention

It is an object of the invention to provide a kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus, the Chinese medicine composition Selected medicinal material compatibility is suitable, and all medicine phases, which are closed, has effects that clearing heat and detoxicating, clearing heat, relieving sore-throat, eliminating stasis to subdue swelling, anti-inflammatory analgetic, can be quick Promote fester wound healing, determined curative effect.

The above-mentioned purpose of the present invention is realized by following technical proposals：

A kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus, be made the Chinese medicine composition raw material composition and Parts by weight are：12-17 parts of great burdock achene, 7-12 parts of Asian puccoon, 4-9 parts of indian skullcap herb with root, 15-20 parts of eupatorium, 10-15 parts of canarium pimela, the root of kudzu vine 8-12 parts, 2-5 parts of cacumen biotae, tuber of dwarf lilyturf 3-7 part, 11-14 parts of dandelion, 9-15 parts of folium isatidis, 3-6 parts of lotus leaf, 8-13 parts of peach branch, 3-5 parts of cherry stone, 1-3 parts of cape jasmine, 5-10 parts of aloe, 3-6 parts of balsam pear, 8-13 parts of Herba Andrographitis, 3-5 parts of HERBA CIRSII, caulis trachelospermi 11- 15 parts, 5-10 parts of caulis lonicerae, 2-5 parts of Momordica grosvenori, 4-9 parts of rush, 12-20 parts of Sagina subulata, 10-16 parts of Radix zanthoxyli, indigo naturalis 3-8 Part, 5-12 parts of the coptis, 5-10 parts of lophatherum gracile, 13-16 parts of pseudo-ginseng, 3-10 parts of moutan bark.

Further, be made the Chinese medicine composition raw material composition and parts by weight be：12 parts of great burdock achene, Asian puccoon 10 Part, 9 parts of indian skullcap herb with root, 15 parts of eupatorium, 15 parts of canarium pimela, 8 parts of the root of kudzu vine, 5 parts of cacumen biotae, 3 parts of the tuber of dwarf lilyturf, 14 parts of dandelion, folium isatidis 9 Part, 6 parts of lotus leaf, 8 parts of peach branch, 5 parts of cherry stone, 1 part of cape jasmine, 10 parts of aloe, 6 parts of balsam pear, 8 parts of Herba Andrographitis, 3 parts of HERBA CIRSII, network 15 parts of stone rattan, 5 parts of caulis lonicerae, 3 parts of Momordica grosvenori, 5 parts of rush, 12 parts of Sagina subulata, 16 parts of Radix zanthoxyli, 3 parts of indigo naturalis, the coptis 12 Part, 5 parts of lophatherum gracile, 16 parts of pseudo-ginseng, 10 parts of moutan bark.

Further, be made the Chinese medicine composition raw material composition and parts by weight be：17 parts of great burdock achene, Asian puccoon 12 Part, 4 parts of indian skullcap herb with root, 20 parts of eupatorium, 10 parts of canarium pimela, 12 parts of the root of kudzu vine, 2 parts of cacumen biotae, 7 parts of the tuber of dwarf lilyturf, 11 parts of dandelion, folium isatidis 15 Part, 3 parts of lotus leaf, 13 parts of peach branch, 3 parts of cherry stone, 3 parts of cape jasmine, 5 parts of aloe, 4 parts of balsam pear, 10 parts of Herba Andrographitis, 4 parts of HERBA CIRSII, network 13 parts of stone rattan, 6 parts of caulis lonicerae, 4 parts of Momordica grosvenori, 8 parts of rush, 20 parts of Sagina subulata, 10 parts of Radix zanthoxyli, 8 parts of indigo naturalis, 5 parts of the coptis, 10 parts of lophatherum gracile, 13 parts of pseudo-ginseng, 3 parts of moutan bark.

Further, be made the Chinese medicine composition raw material composition and parts by weight be：13 parts of great burdock achene, 7 parts of Asian puccoon, 5 parts of indian skullcap herb with root, 18 parts of eupatorium, 11 parts of canarium pimela, 9 parts of the root of kudzu vine, 4 parts of cacumen biotae, 6 parts of the tuber of dwarf lilyturf, 12 parts of dandelion, 13 parts of folium isatidis, 4 parts of lotus leaf, 9 parts of peach branch, 4 parts of cherry stone, 2 parts of cape jasmine, 6 parts of aloe, 5 parts of balsam pear, 12 parts of Herba Andrographitis, 3 parts of HERBA CIRSII, caulis trachelospermi 12 parts, 9 parts of caulis lonicerae, 4 parts of Momordica grosvenori, 7 parts of rush, 13 parts of Sagina subulata, 11 parts of Radix zanthoxyli, 4 parts of indigo naturalis, 6 parts of the coptis, henon bamboo 6 parts of leaf, 14 parts of pseudo-ginseng, 5 parts of moutan bark.

Further, be made the Chinese medicine composition raw material composition and parts by weight be：16 parts of great burdock achene, 8 parts of Asian puccoon, 8 parts of indian skullcap herb with root, 16 parts of eupatorium, 14 parts of canarium pimela, 11 parts of the root of kudzu vine, 3 parts of cacumen biotae, 5 parts of the tuber of dwarf lilyturf, 13 parts of dandelion, 14 parts of folium isatidis, 5 parts of lotus leaf, 12 parts of peach branch, 3 parts of cherry stone, 1 part of cape jasmine, 10 parts of aloe, 4 parts of balsam pear, 11 parts of Herba Andrographitis, 4 parts of HERBA CIRSII, trachelospermum jasminoide 14 parts of rattan, 8 parts of caulis lonicerae, 3 parts of Momordica grosvenori, 6 parts of rush, 17 parts of Sagina subulata, 15 parts of Radix zanthoxyli, 7 parts of indigo naturalis, 11 parts of the coptis, 9 parts of lophatherum gracile, 13 parts of pseudo-ginseng, 7 parts of moutan bark.

Further, be made the Chinese medicine composition raw material composition and parts by weight be：15 parts of great burdock achene, 9 parts of Asian puccoon, 7 parts of indian skullcap herb with root, 19 parts of eupatorium, 13 parts of canarium pimela, 10 parts of the root of kudzu vine, 4 parts of cacumen biotae, 4 parts of the tuber of dwarf lilyturf, 11 parts of dandelion, 11 parts of folium isatidis, 5 parts of lotus leaf, 10 parts of peach branch, 5 parts of cherry stone, 3 parts of cape jasmine, 8 parts of aloe, 6 parts of balsam pear, 9 parts of Herba Andrographitis, 5 parts of HERBA CIRSII, caulis trachelospermi 12 parts, 7 parts of caulis lonicerae, 5 parts of Momordica grosvenori, 9 parts of rush, 15 parts of Sagina subulata, 12 parts of Radix zanthoxyli, 5 parts of indigo naturalis, 9 parts of the coptis, henon bamboo 8 parts of leaf, 14 parts of pseudo-ginseng, 9 parts of moutan bark.

Further, be made the Chinese medicine composition raw material composition and parts by weight be：14 parts of great burdock achene, 9 parts of Asian puccoon, 6 parts of indian skullcap herb with root, 17 parts of eupatorium, 13 parts of canarium pimela, 10 parts of the root of kudzu vine, 4 parts of cacumen biotae, 4 parts of the tuber of dwarf lilyturf, 11 parts of dandelion, 11 parts of folium isatidis, 5 parts of lotus leaf, 10 parts of peach branch, 5 parts of cherry stone, 3 parts of cape jasmine, 8 parts of aloe, 3 parts of balsam pear, 8 parts of Herba Andrographitis, 5 parts of HERBA CIRSII, caulis trachelospermi 15 parts, 7 parts of caulis lonicerae, 2 parts of Momordica grosvenori, 4 parts of rush, 19 parts of Sagina subulata, 14 parts of Radix zanthoxyli, 6 parts of indigo naturalis, 7 parts of the coptis, henon bamboo 8 parts of leaf, 14 parts of pseudo-ginseng, 4 parts of moutan bark.

Chinese medicine composition provided by the present invention for the postoperative oral care of cancer of the esophagus, it is using common Chinese herbal medicine as original Material, gives full play to the property of medicine of each component：

Great burdock achene：There is dispelling wind and heat from the body, facilitaing lung promoting eruption, relieving sore-throat dissipating bind, removing toxicity for detumescence, cough due to wind-heat evil, pharynx is cured mainly Larynx swells and ache, macula is impermeable, rubella itch, sore swollen toxin.Drying and ripening selected from feverfew burdock Arctium lappa L. Fruit.

Asian puccoon：It is cold in nature, it is sweet, salty.The thoughts of returning home, Liver Channel.Its major function：Cool blood, promoting blood circulation, promoting eruption of detoxifying.

Indian skullcap herb with root：Pungent, hardship, bosom is cold；The thoughts of returning home, liver, lung channel.It is clearing heat and detoxicating, promoting blood circulation and stopping pain, hemostasia and detumescence.Main carbuncle swells malignant boil Poison, lung carbuncle, acute appendicitis, scrofula, venomous snake bite, lung heat cough and asthma, toothache, larynx numbness, pharyngalgia, arthralgia and myalgia is spitted blood, and spitting of blood is had blood in stool, fallen Play damage, traumatic bleeding, pruitus.《Quanzhou book on Chinese herbal medicine》Carry：" clearing heat and detoxicating, Huang is moved back in detumescence, and by blood broken stasis of blood, removing pus and relieving carbuncle is cool Blood stops blooding, throat.All larynxs Huang is cured mainly, lung-fire hyperpyrexia is also controlled and breathes with cough, is spitted blood, hemoptysis spitting of blood, crazy blood is had a pain, knife wound bleeding, Malignant sore carbuncle swells, tiger, dog bite.”

Eupatorium is pungent, cold in nature, returns spleen, stomach, with stomach invigorating, diuresis, clearing damp, menstruation regulating, stagnation resolvation, soothing the liver, Xie Yu, qi-regulating, The effects such as invigorating the spleen, breathing can be suppressed, make decreased heart rate, temperature decline and causes all diseases of glycosuria at hyperglycemia.

Canarium pimela：It is sour, puckery, it is mild-natured；Returns spleen, lung channel.Hemostasis, Li Shui, removing toxic substances.Main hematemesis with internal injury, phlegm blood of coughing, oedema, Acute mastitis, traumatism and bleeding.《The south of the Five Ridges is gathered medicinal herbs record》Carry：" fire forges sustainability, hemostasis and phlegm.Few salt marsh it, name olive drum, acute mastitis is from the beginning of decocting water That washes can disappear.”

The root of kudzu vine, it is sweet, pungent, it is cool in nature.Enter spleen, stomach.With rising Yang expelling pathogenic factors from muscles and skin, promoting eruption antidiarrheal, relieving restlessness stops effect of temperature.For Typhoid fever, warm headache Xiang Qiang, dysphoria with smothery sensation are quenched one's thirst, and diarrhea, dysentery, ecchymosis is impermeable, hypertension, angina pectoris, deaf.Clinically it is used for controlling High blood pressure neck pain, coronary disease and angina pectoris are treated, but also with hypoglycemic effect.

Cacumen biotae, bitter, puckery, cold nature, return lung, liver, large intestine channel, cooling blood and hemostasis, cough-relieving apophlegmatic, wind-damp dispelling dissipates pyogenic infections.It is main Spitting of blood is controlled, is spitted blood, bleeding from five sense organs or subcutaneous tissue, hematuria, bloody flux, discharging fresh blood stool, uterine bleeding is more than, coughing with a lot of sputum, arthralgia pain due to rheumatism, erysipelas, mumps, is scalded Wound.《Mingyi Bielu》：Main haematemesis, bleeding from five sense organs or subcutaneous tissue, dysentery blood, metrorrhagia are red white.Make light of one's life by commiting suicide QI invigorating, make us resistance to cold and heat, go arthritis with fixed pain caused by dampness, myogenic.

The tuber of dwarf lilyturf, sweet, slight bitter is slightly cold.The thoughts of returning home, lung, stomach.Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.For dryness of the lung dry cough.Consumptive disease is coughed Cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines；Pharyngeal diphtheria.

Dandelion：For feverfew dandelion Taraxacum mongolicum Hand.-Mazz., alkali ground dandelion Taraxacum sinicum Kitag. or the drying herb for belonging to several plants together.It is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia. For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.

Folium isatidis：Bitter, it is cold in nature.Return liver, the heart, stomach, the spleen channel.It is clearing heat and detoxicating, blood cooling and ecchymoses removing.For pyreticosis hyperpyrexia polydipsia； Coma；Macula；Spit blood；Bleeding from five sense organs or subcutaneous tissue；Jaundice；Rush down dysentery；Erysipelas；Larynx numbness；Aphtha；Mumps.

Lotus leaf：Bitter, it is mild-natured；Return liver, spleen, stomach.Clearing away summerheat, sending up the lucid yang, cooling blood and hemostasis.For hot summer weather polydipsia, Summer heat damp diarrhea, splenasthenic diarrhea, blood-head tells nosebleed, uterine bleeding of having blood in stool, hypotensive, reducing blood lipid.Modern study shows that lotus leaf has reducing blood lipid work With.

Peach branch, bitter, flat, the thoughts of returning home, liver, large intestine channel, Li Shui are promoting blood circulation and removing blood stasis, and dredging collateral controls pain in the chest and abdomen.

Cherry stone：It is pungent, it is warm-natured；Return lung is passed through.Promoting eruption is delivered, the knurl that disappears goes scar, promoting qi circulation and relieving pain.Main acne rash initial stage is sent out not thoroughly Freely, cicatrix of skin, goiter and tumor, hernia pain.《Book on Chinese herbal medicine is new again》Carry：" Toxin-Vanquishing, the subcutaneous ulcer that disappears knurl.”

Its cold in nature, bitter of cape jasmine, function is with curing mainly：Purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body,《Sheng Nong's herbal classic》： " cure mainly perverse trend in five, white leprosy, red leprosy, sore ....”

Aloe：It is bitter, cold.Return liver, large intestine channel.Under rushing down, clear liver, desinsection.For constipation with heat retention；Irascibility is had a headache；Hot eyes infantile convulsion； Abdominal pain due to enterositosis；Mange；Hemorrhoid complicated by anal fistula；Solve crotons poison.

Balsam pear：It is cold in nature, bitter；Enter the heart, Liver Channel；Clearing summer heat, improving eyesight removing toxic substances, diuresis cool blood cures mainly pyreticosis polydipsia, heatstroke Erysipelas, hot eyes carbuncle swells, dysentery, the illness such as oliguresis.Heat, the effect of improving eyesight is detoxified are washed with the administration that disappears.Pharmacological research shows both at home and abroad, Balsam pear has hypoglycemic, antifertility, resists and dash forward.

Herba Andrographitis：Bitter, cold in nature, the thoughts of returning home, lung, large intestine, bladder warp, with clearing heat and detoxicating, cool blood, detumescence, the work(of eliminating dampness Effect, cures mainly cold, fever, abscess of throat, aphthae, pertussis overstrain cough, dysentery, puckery pain of heat gonorrhea, carbuncle swells sore, poisonous snake stings The card such as wound.

HERBA CIRSII, sweet, bitter, cold.The thoughts of returning home, Liver Channel.Cooling blood and hemostasis, dissipates stasis of blood removing toxicity for eliminating carbuncles.Blood-head goes out blood trouble.This moral character category is cold Cool, no matter the kind heat purified the blood point and cooling blood and hemostasis tell and cough up bleeding from five sense organs or subcutaneous tissue, the bleeding such as uterine bleeding of having blood in stool person caused by blood-heat bleeding is all optional With.And can inducing diuresis for treating strangurtia, therefore it is outstanding kind control hematuria, blood strangury, can single application, also can the compatibility dried rhizome of rehmannia, talcum, mountain Cape jasmine, lophatherum gracile etc.. Heat toxin carbuncle swells.This product can clearing heat and detoxicating, eliminating stasis to subdue swelling, with controlling pathopyretic ulcer from the beginning of the card swollen and ache.

Caulis trachelospermi, bitter in taste, pungent, cold nature.The thoughts of returning home, liver and kidney channel.Cure mainly and remove obstruction in channels to relieve pain, heat clearing and blood cooling, removing toxicity for detumescence. Main arthralgia pain due to rheumatism, soreness of waist and knee joint, muscle arteries and veins contraction, abscess of throat, furuncle swelling toxin, traumatic injury, traumatism and bleeding.

Caulis lonicerae：It is sweet, it is cold in nature.Attach to the lung and stomach meridians.It is clearing heat and detoxicating, dispelling wind dredging collateral.For warm disease heating, toxic-heat and blood stasis, carbuncle Swollen sore, beriberoid pyretic arthralgia, redness and swelling of joints heat pain.

Momordica grosvenori, it is sweet, it is cool.Return lung, large intestine channel.Major function：Clearing heat and moistening lung, laxation defaecation.For lung-fire cough caused by dryness, pharyngalgia Aphonia, dry constipation of intestines.

Rush：Base：For the stem marrow or herb of rush family plant rush.Chemical analysis：Stem marrow fibre-bearing, fat Oil, protein etc..Stem contains polysaccharide.Nature and flavor：It is sweet light, tremble with fear.Channel tropism：Enter the heart, lung, small intestinl channel.Major function：Clearing heart fire, profit Urine is treating stranguria.Control gonorrhoea, oedema, difficult urination, jaundice with damp-heat pathogen, dysphoria and insomnia, nocturnal fretfulness in infants, larynx numbness, wound.

Sagina subulata：Originate as the herb or whole herb with root of euphorbia plant Common Leafflower Herb.Nature and flavor are sweet, bitter, cool.Channel tropism：Return liver, Lung channel.Major function：Calming liver and clearing heat, promoting diuresis to remove toxic substance.Control enteritis, dysentery, catarrhal jaundice, nephritic dropsy, urinary tract infections, children Infantile malnutrition due to digestive disturbances or intestinalparasites, pinkeye mesh screen, aphtha head sore, nameless sores or boils.

Radix zanthoxyli：It is mild-natured, it is bitter, pungent, it is slightly poisonous, return stomach, Liver Channel, promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, dispelling wind and removing obstruction in the meridians.

Indigo naturalis, it is salty, tremble with fear.Return liver warp.It is clearing heat and detoxicating, cool blood, arresting convulsion.For febrile virulent maculae, blood-head tells nosebleed, pectoralgia hemoptysis, Aphtha, mumps, larynx numbness, pediatric epilepsy scared.

The coptis, it is bitter, tremble with fear.The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Major function：Heat-clearing and damp-drying drug, purging intense heat and detonicating.For wet Hot feeling of fullness, vomits acid regurgitation, and rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache is quenched one's thirst, Carbuncle swells furunculosis；Eczema is controlled outside, wet sore, duct is suppurated.It is burning hot that prepared RHIZOMA COPTIDIS with vino is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For hot eyes, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach and Stomach preventing or arresting vomiting.Mutually tied for fever and chills, damp and hot middle resistance, feeling of fullness vomiting.The easypro liver anti-vomiting of cornel coptis.For liver-stomach disharmony, vomiting is gulped down Acid.

Lophatherum gracile：It is sweet, light, tremble with fear.The thoughts of returning home, stomach, small intestinl channel.Effect is with curing mainly：Clearing heat and relieving fidgetness, diuresis.For pyreticosis polydipsia, Hot urination drenches pain, aphthae.

Pseudo-ginseng：Pseudo-ginseng property sugariness slight bitter, warm-natured, Return liver, stomach are used as medicine with root, root-like stock.It is rare traditional Chinese medicine, raw use can Hemostasia and dissipation blood stasis, swelling and pain relieving, with good hemostasia effect, significant hematopoiesis function；Coronary microcirculation, three can be tightened and improved Seven are used as medicine with a long history, act on the peculiar treasured being considered as by ancient Chinese medicine doctor in medicine, therefore have the saying of " invaluable ".Pseudo-ginseng " taste micro-sweet And bitter, the taste quite like ginseng." " all canes flutter hurt, and the dripping person of hemostasis chews stopping for rotten net for catching birds or fish immediately, and bruise person is to dissipate.If by During cane, one, two money are first taken, then the blood not centre of punch, it is preferably taken especially after cane, postpartum clothes are also good.On the whole this medicine temperature, sweet and slightly bitter taste, and Bright, cloudy blood system of fainting the medicine of sun, therefore all blood disease can be controlled ".《Book on Chinese herbal medicine is looked for the truth》Record：" pseudo-ginseng, common people only know function hemostasis and pain-relieving. Hardly realize that pain aches work because of blood stasis, blood stops blood because of deposited dissipate.The bitter temperature of pseudo-ginseng smell, can be in its blood stasis of blood systemization." pseudo-ginseng can increase Coronary blood flow, reducing heart rate reduces myocardial oxygen consumption, and the myocardium oxygen-resistant ability of increase improves microcirculation, releases smooth muscle spasm Effect.

Moutan bark, it is bitter, pungent, it is slightly cold.The thoughts of returning home, liver and kidney channel.Clearing heat and cooling blood, it is promoting blood circulation and removing blood stasis.For febrile virulent maculae, nosebleed of spitting blood Blood, night fever abating at dawn, lossless hectic fever due to yin, closed dysmenorrhea, carbuncle sore tumefacting virus, the pain of injury caused by falling and tumbling.

Medicinal material compatibility selected by a kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus of the present invention is suitable, all medicine phases Conjunction has effects that clearing heat and detoxicating, clearing heat, relieving sore-throat, eliminating stasis to subdue swelling, anti-inflammatory analgetic, can rapidly promote the wound healing that festers, curative effect is true Cut, for having the advantages that instant effect, cure rate are high for cancer of the esophagus post-operative recovery, have no toxic side effect, safe ready, can be extensive For cancer of the esophagus post-operative recovery.

Embodiment

To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with embodiment to this hair Bright technical scheme is clearly and completely described.Obviously, described embodiment is the part of the present invention, rather than entirely The embodiment in portion.Based on described embodiments of the invention, those of ordinary skill in the art are before without creative work The every other embodiment obtained is put, the scope of protection of the invention is belonged to.

A kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus of the present invention, the bulk drug of the Chinese medicine composition By great burdock achene, Asian puccoon, indian skullcap herb with root, eupatorium, canarium pimela, the root of kudzu vine, cacumen biotae, the tuber of dwarf lilyturf, dandelion, folium isatidis, lotus leaf, peach branch, cherry Core, cape jasmine, aloe, balsam pear, Herba Andrographitis, HERBA CIRSII, caulis trachelospermi, caulis lonicerae, Momordica grosvenori, rush, Sagina subulata, Radix zanthoxyli, green grass or young crops Black pigment used by women in ancient times to paint their eyebrows, the coptis, lophatherum gracile, pseudo-ginseng, moutan bark composition.

A kind of raw material of Chinese medicine composition for the postoperative oral care of cancer of the esophagus of the present invention is constituted and weight is：

12 parts of great burdock achene, 10 parts of Asian puccoon, 9 parts of indian skullcap herb with root, 15 parts of eupatorium, 15 parts of canarium pimela, 8 parts of the root of kudzu vine, 5 parts of cacumen biotae, wheat 3 parts of winter, 14 parts of dandelion, 9 parts of folium isatidis, 6 parts of lotus leaf, 8 parts of peach branch, 5 parts of cherry stone, 1 part of cape jasmine, 10 parts of aloe, balsam pear 6 Part, 8 parts of Herba Andrographitis, 3 parts of HERBA CIRSII, 15 parts of caulis trachelospermi, 5 parts of caulis lonicerae, 3 parts of Momordica grosvenori, 5 parts of rush, 12 parts of Sagina subulata, two 16 parts of face pin, 3 parts of indigo naturalis, 12 parts of the coptis, 5 parts of lophatherum gracile, 16 parts of pseudo-ginseng, 10 parts of moutan bark.

Embodiment 2：

17 parts of great burdock achene, 12 parts of Asian puccoon, 4 parts of indian skullcap herb with root, 20 parts of eupatorium, 10 parts of canarium pimela, 12 parts of the root of kudzu vine, 2 parts of cacumen biotae, wheat 7 parts of winter, 11 parts of dandelion, 15 parts of folium isatidis, 3 parts of lotus leaf, 13 parts of peach branch, 3 parts of cherry stone, 3 parts of cape jasmine, 5 parts of aloe, balsam pear 4 Part, 10 parts of Herba Andrographitis, 4 parts of HERBA CIRSII, 13 parts of caulis trachelospermi, 6 parts of caulis lonicerae, 4 parts of Momordica grosvenori, 8 parts of rush, 20 parts of Sagina subulata, 10 parts of Radix zanthoxyli, 8 parts of indigo naturalis, 5 parts of the coptis, 10 parts of lophatherum gracile, 13 parts of pseudo-ginseng, 3 parts of moutan bark.

Embodiment 3：

13 parts of great burdock achene, 7 parts of Asian puccoon, 5 parts of indian skullcap herb with root, 18 parts of eupatorium, 11 parts of canarium pimela, 9 parts of the root of kudzu vine, 4 parts of cacumen biotae, the tuber of dwarf lilyturf 6 parts, 12 parts of dandelion, 13 parts of folium isatidis, 4 parts of lotus leaf, 9 parts of peach branch, 4 parts of cherry stone, 2 parts of cape jasmine, 6 parts of aloe, 5 parts of balsam pear, 12 parts of Herba Andrographitis, 3 parts of HERBA CIRSII, 12 parts of caulis trachelospermi, 9 parts of caulis lonicerae, 4 parts of Momordica grosvenori, 7 parts of rush, 13 parts of Sagina subulata, two sides 11 parts of pin, 4 parts of indigo naturalis, 6 parts of the coptis, 6 parts of lophatherum gracile, 14 parts of pseudo-ginseng, 5 parts of moutan bark.

Embodiment 4：

16 parts of great burdock achene, 8 parts of Asian puccoon, 8 parts of indian skullcap herb with root, 16 parts of eupatorium, 14 parts of canarium pimela, 11 parts of the root of kudzu vine, 3 parts of cacumen biotae, wheat 5 parts of winter, 13 parts of dandelion, 14 parts of folium isatidis, 5 parts of lotus leaf, 12 parts of peach branch, 3 parts of cherry stone, 1 part of cape jasmine, 10 parts of aloe, balsam pear 4 Part, 11 parts of Herba Andrographitis, 4 parts of HERBA CIRSII, 14 parts of caulis trachelospermi, 8 parts of caulis lonicerae, 3 parts of Momordica grosvenori, 6 parts of rush, 17 parts of Sagina subulata, 15 parts of Radix zanthoxyli, 7 parts of indigo naturalis, 11 parts of the coptis, 9 parts of lophatherum gracile, 13 parts of pseudo-ginseng, 7 parts of moutan bark.

Embodiment 5：

15 parts of great burdock achene, 9 parts of Asian puccoon, 7 parts of indian skullcap herb with root, 19 parts of eupatorium, 13 parts of canarium pimela, 10 parts of the root of kudzu vine, 4 parts of cacumen biotae, wheat 4 parts of winter, 11 parts of dandelion, 11 parts of folium isatidis, 5 parts of lotus leaf, 10 parts of peach branch, 5 parts of cherry stone, 3 parts of cape jasmine, 8 parts of aloe, balsam pear 6 Part, 9 parts of Herba Andrographitis, 5 parts of HERBA CIRSII, 12 parts of caulis trachelospermi, 7 parts of caulis lonicerae, 5 parts of Momordica grosvenori, 9 parts of rush, 15 parts of Sagina subulata, two 12 parts of face pin, 5 parts of indigo naturalis, 9 parts of the coptis, 8 parts of lophatherum gracile, 14 parts of pseudo-ginseng, 9 parts of moutan bark.

Embodiment 6：

14 parts of great burdock achene, 9 parts of Asian puccoon, 6 parts of indian skullcap herb with root, 17 parts of eupatorium, 13 parts of canarium pimela, 10 parts of the root of kudzu vine, 4 parts of cacumen biotae, wheat 4 parts of winter, 11 parts of dandelion, 11 parts of folium isatidis, 5 parts of lotus leaf, 10 parts of peach branch, 5 parts of cherry stone, 3 parts of cape jasmine, 8 parts of aloe, balsam pear 3 Part, 8 parts of Herba Andrographitis, 5 parts of HERBA CIRSII, 15 parts of caulis trachelospermi, 7 parts of caulis lonicerae, 2 parts of Momordica grosvenori, 4 parts of rush, 19 parts of Sagina subulata, two 14 parts of face pin, 6 parts of indigo naturalis, 7 parts of the coptis, 8 parts of lophatherum gracile, 14 parts of pseudo-ginseng, 4 parts of moutan bark.

The preparation method of Chinese medicine composition described in 1-6 of the embodiment of the present invention, comprises the following steps：

(1) take folium isatidis, indian skullcap herb with root, aloe, balsam pear to twist juice, filter impurity, stay juice, it is standby；

(2) after surplus stock medicine is mixed, crushed by pulverizer, medicinal powder fineness is 40-60 mesh；

(3) it is 90%-95%'s to add medicinal powder made from step (2) relative to 4-6 times of determining alcohol measured of medicinal powder quality Soaked 1.5-2.5 hours in ethanol, heating extraction 2 times, every time backflow 2.5-3 hours, take supernatant, merge extract solution, 150- 200 mesh are filtered, and obtain the first extract solution；The determining alcohol that the dregs of a decoction that filtering is obtained add relative to 2-3 times of the dregs of a decoction quality is 85%-90% ethanol, is heated to reflux 2 hours, extracts, and filtering obtains the second extract solution；First extract solution and second are extracted Liquid merges, and be concentrated under reduced pressure removing alcohol solvent, dries, and obtains dry cream, 80 mesh fine powders are made after crushing；

(4) fine powder made from juice made from step (1), step (3) is mixed, after drying, tablet is made.

Clinical reasoning：

In order to verify the effect of Chinese medicine composition of the present invention, in September, 2014 in May, -2016,343 are randomly choosed at outpatient service Example esophageal cancer patients clinical observation, patient is randomly divided into two groups, treatment group 173, wherein male 80, women 93, age 26-62 Sui, average age 41.7 years old, the course of disease -9 years 4 months；Control group 170, wherein male 85, women 85, age 27-63 Sui, average age 42.5 years old, the course of disease -8 years 3 months.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without aobvious Difference is write, with comparativity.

Treatment method：

Treatment group：Patient distinguishes tablet manufactured by oral embodiment 3, and 3 times a day, and 2 tablets once, after meal half an hour Nei Wenkai Water delivery service, 7 days as one therapeutic course continuously takes 2 to 4 courses for the treatment of, and serious patient increases the amount of discretion.

Control group：Take esophagus flat scattered, by specification is used, and serious patient increases the amount of discretion.

Therapeutic evaluation

Cure：Swallow after choking feeling, breastbone and pain, acupuncture sample or drawing friction sample pain under xiphoid-process, become thin, be dehydrated, The symptom such as powerless disappears, and physical recovery is normal.

Effectively：Above-mentioned symptom has been alleviated.

It is invalid：Illness is unchanged.

Result of the test

Result of the test statistical analysis is as shown in table 1：

The efficient comparative analysis of 1 two groups of patients of table

Group	Number of cases	Cure	Effectively	It is invalid	It is total effective
						Treatment group	173	127 (73.4%)	45 (26.0%)	1 (0.6%)	172 (99.4%)
Control group	170	54 (31.8%)	47 (27.6%)	69 (40.6%)	101 (59.4%)

Wherein, total effective rate=cure rate+obvious effective rate.

Conclusion (of pressure testing)

Compared with control group, the average cure rate for the treatment of group is 99.4%, and control group is 59.4%, and treatment group compares control group It is high 40 percentage points, illustrate that Chinese medicine composition of the present invention has very significant technical advantage compared with prior art, obtain New, creative breakthrough.

Model case：

Case 1

Certain is practised, 35 years old, Qingdao people from Shinan District.Patient because of the pharyngeal inconvenience that occurs having a meal, drink water that unobstructed, gas is not smooth, has foreign matter The symptoms such as sense are to our hospital.Cancer of the esophagus is diagnosed as on inspection.Cancer of the esophagus Post operation is carried out, Chinese medicine preparation 2 of the present invention is taken The course for the treatment of, picks body；Continue to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, body recovery from illness, follow-up is not recurred, thoroughly cured.

Case 2

Peng, 54 years old, Qingdao Jimo people.Patient suffers from cancer of the esophagus more than 1 year, during which has western medicine, food can only eat paste Shape food, drinks water lighter, gas is not smooth, and esophagus has foreign body sensation strong and with pain.Implement Post operation to take for after treatment 3 courses for the treatment of of Chinese medicine preparation of the present invention, body starts to take a turn for the better；Continue to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, body is fully recovered, with Visit is not recurred, is thoroughly cured.

Case 3：

Deng, 42 years old, Jinan City people from Lixia District.Patient occur swallowing it is uncomfortable, itch with pharynx, pharyngalgia, cough, hoarseness etc. Symptom, can only eat spoon meat, to our hospital, and cancer of the esophagus is diagnosed as by checking.Implement Post operation to take in the present invention 2 courses for the treatment of of medicine preparation, above-mentioned symptom takes a turn for the better；Continue to take after 1 course for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom disappears, wound Healing, body recovery from illness, follow-up is not recurred.

Finally it should be noted that：The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although The present invention is described in detail with reference to the foregoing embodiments, it will be understood by those within the art that：It still may be used To be modified to the technical scheme described in foregoing embodiments, or equivalent substitution is carried out to which part technical characteristic； And these modifications or replacement, the essence of appropriate technical solution is departed from the scope of various embodiments of the present invention technical scheme.

Claims

1. a kind of Chinese medicine composition for the postoperative oral care of cancer of the esophagus, it is characterised in that：The Chinese medicine composition is made Raw material is constituted and parts by weight are：12-17 parts of great burdock achene, 7-12 parts of Asian puccoon, 4-9 parts of indian skullcap herb with root, 15-20 parts of eupatorium, canarium pimela 10- 15 parts, 8-12 parts of the root of kudzu vine, 2-5 parts of cacumen biotae, tuber of dwarf lilyturf 3-7 part, 11-14 parts of dandelion, 9-15 parts of folium isatidis, 3-6 parts of lotus leaf, peach 8-13 parts of branch, 3-5 parts of cherry stone, 1-3 parts of cape jasmine, 5-10 parts of aloe, 3-6 parts of balsam pear, 8-13 parts of Herba Andrographitis, 3-5 parts of HERBA CIRSII, 11-15 parts of caulis trachelospermi, 5-10 parts of caulis lonicerae, 2-5 parts of Momordica grosvenori, 4-9 parts of rush, 12-20 parts of Sagina subulata, Radix zanthoxyli 10-16 Part, 3-8 parts of indigo naturalis, 5-12 parts of the coptis, 5-10 parts of lophatherum gracile, 13-16 parts of pseudo-ginseng, 3-10 parts of moutan bark.

2. the Chinese medicine composition according to claim 1 for the postoperative oral care of cancer of the esophagus, it is characterised in that：Institute is made State Chinese medicine composition raw material composition and parts by weight be：12 parts of great burdock achene, 10 parts of Asian puccoon, 9 parts of indian skullcap herb with root, 15 parts of eupatorium, crow 15 parts of olive, 8 parts of the root of kudzu vine, 5 parts of cacumen biotae, 3 parts of the tuber of dwarf lilyturf, 14 parts of dandelion, 9 parts of folium isatidis, 6 parts of lotus leaf, 8 parts of peach branch, cherry stone 5 Part, 1 part of cape jasmine, 10 parts of aloe, 6 parts of balsam pear, 8 parts of Herba Andrographitis, 3 parts of HERBA CIRSII, 15 parts of caulis trachelospermi, 5 parts of caulis lonicerae, Momordica grosvenori 3 Part, 5 parts of rush, 12 parts of Sagina subulata, 16 parts of Radix zanthoxyli, 3 parts of indigo naturalis, 12 parts of the coptis, 5 parts of lophatherum gracile, 16 parts of pseudo-ginseng, moutan bark 10 parts.

3. the Chinese medicine composition according to claim 1 for the postoperative oral care of cancer of the esophagus, it is characterised in that：Institute is made State Chinese medicine composition raw material composition and parts by weight be：17 parts of great burdock achene, 12 parts of Asian puccoon, 4 parts of indian skullcap herb with root, 20 parts of eupatorium, crow 10 parts of olive, 12 parts of the root of kudzu vine, 2 parts of cacumen biotae, 7 parts of the tuber of dwarf lilyturf, 11 parts of dandelion, 15 parts of folium isatidis, 3 parts of lotus leaf, 13 parts of peach branch, cherry 3 parts of core, 3 parts of cape jasmine, 5 parts of aloe, 4 parts of balsam pear, 10 parts of Herba Andrographitis, 4 parts of HERBA CIRSII, 13 parts of caulis trachelospermi, 6 parts of caulis lonicerae, arhat Really 4 parts, 8 parts of rush, 20 parts of Sagina subulata, 10 parts of Radix zanthoxyli, 8 parts of indigo naturalis, 5 parts of the coptis, 10 parts of lophatherum gracile, 13 parts of pseudo-ginseng is male 3 parts of the root bark of tree peony.

4. the Chinese medicine composition according to claim 1 for the postoperative oral care of cancer of the esophagus, it is characterised in that：Institute is made State Chinese medicine composition raw material composition and parts by weight be：13 parts of great burdock achene, 7 parts of Asian puccoon, 5 parts of indian skullcap herb with root, 18 parts of eupatorium, canarium pimela 11 parts, 9 parts of the root of kudzu vine, 4 parts of cacumen biotae, 6 parts of the tuber of dwarf lilyturf, 12 parts of dandelion, 13 parts of folium isatidis, 4 parts of lotus leaf, 9 parts of peach branch, cherry stone 4 Part, 2 parts of cape jasmine, 6 parts of aloe, 5 parts of balsam pear, 12 parts of Herba Andrographitis, 3 parts of HERBA CIRSII, 12 parts of caulis trachelospermi, 9 parts of caulis lonicerae, Momordica grosvenori 4 Part, 7 parts of rush, 13 parts of Sagina subulata, 11 parts of Radix zanthoxyli, 4 parts of indigo naturalis, 6 parts of the coptis, 6 parts of lophatherum gracile, 14 parts of pseudo-ginseng, moutan bark 5 Part.

5. the Chinese medicine composition according to claim 1 for the postoperative oral care of cancer of the esophagus, it is characterised in that：Institute is made State Chinese medicine composition raw material composition and parts by weight be：16 parts of great burdock achene, 8 parts of Asian puccoon, 8 parts of indian skullcap herb with root, 16 parts of eupatorium, canarium pimela 14 parts, 11 parts of the root of kudzu vine, 3 parts of cacumen biotae, 5 parts of the tuber of dwarf lilyturf, 13 parts of dandelion, 14 parts of folium isatidis, 5 parts of lotus leaf, 12 parts of peach branch, cherry stone 3 parts, 1 part of cape jasmine, 10 parts of aloe, 4 parts of balsam pear, 11 parts of Herba Andrographitis, 4 parts of HERBA CIRSII, 14 parts of caulis trachelospermi, 8 parts of caulis lonicerae, Momordica grosvenori 3 parts, 6 parts of rush, 17 parts of Sagina subulata, 15 parts of Radix zanthoxyli, 7 parts of indigo naturalis, 11 parts of the coptis, 9 parts of lophatherum gracile, 13 parts of pseudo-ginseng, tree peony 7 parts of skin.

6. the Chinese medicine composition according to claim 1 for the postoperative oral care of cancer of the esophagus, it is characterised in that：Institute is made State Chinese medicine composition raw material composition and parts by weight be：15 parts of great burdock achene, 9 parts of Asian puccoon, 7 parts of indian skullcap herb with root, 19 parts of eupatorium, canarium pimela 13 parts, 10 parts of the root of kudzu vine, 4 parts of cacumen biotae, 4 parts of the tuber of dwarf lilyturf, 11 parts of dandelion, 11 parts of folium isatidis, 5 parts of lotus leaf, 10 parts of peach branch, cherry stone 5 parts, 3 parts of cape jasmine, 8 parts of aloe, 6 parts of balsam pear, 9 parts of Herba Andrographitis, 5 parts of HERBA CIRSII, 12 parts of caulis trachelospermi, 7 parts of caulis lonicerae, Momordica grosvenori 5 Part, 9 parts of rush, 15 parts of Sagina subulata, 12 parts of Radix zanthoxyli, 5 parts of indigo naturalis, 9 parts of the coptis, 8 parts of lophatherum gracile, 14 parts of pseudo-ginseng, moutan bark 9 Part.

7. the Chinese medicine composition according to claim 1 for the postoperative oral care of cancer of the esophagus, it is characterised in that：Institute is made State Chinese medicine composition raw material composition and parts by weight be：14 parts of great burdock achene, 9 parts of Asian puccoon, 6 parts of indian skullcap herb with root, 17 parts of eupatorium, canarium pimela 13 parts, 10 parts of the root of kudzu vine, 4 parts of cacumen biotae, 4 parts of the tuber of dwarf lilyturf, 11 parts of dandelion, 11 parts of folium isatidis, 5 parts of lotus leaf, 10 parts of peach branch, cherry stone 5 parts, 3 parts of cape jasmine, 8 parts of aloe, 3 parts of balsam pear, 8 parts of Herba Andrographitis, 5 parts of HERBA CIRSII, 15 parts of caulis trachelospermi, 7 parts of caulis lonicerae, Momordica grosvenori 2 Part, 4 parts of rush, 19 parts of Sagina subulata, 14 parts of Radix zanthoxyli, 6 parts of indigo naturalis, 7 parts of the coptis, 8 parts of lophatherum gracile, 14 parts of pseudo-ginseng, moutan bark 4 Part.