CN104288497A - Medicament for treating meningitis and preparation method thereof - Google Patents

Medicament for treating meningitis and preparation method thereof Download PDF

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CN104288497A
CN104288497A CN201410522617.XA CN201410522617A CN104288497A CN 104288497 A CN104288497 A CN 104288497A CN 201410522617 A CN201410522617 A CN 201410522617A CN 104288497 A CN104288497 A CN 104288497A
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herba
folium
rhizoma polygonati
treatment
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李东
袁素萍
袁磊
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Yuan Suping
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Abstract

The invention discloses a medicament for treating meningitis and a preparation method thereof and belongs to the field of traditional Chinese medicine. The medicament comprises the active ingredients: euonymus maackii, radix polygonati officinalis, red rhodobryum, Siberian elm leaves, marshmallow root, libanotis buethorimensis, gentianopsis barbata, averrhoa carambola leaves, tea leaves, tea begonia, ambrosia artemisiifolia, sarel spleenwort herb, piemarker, variegated solomonseal rhizome, dominant pulicaria flower and long pepper. As the crude drugs are selected and combined properly and complement each other, the medicament has the efficacies of purging fire, removing toxin, activating blood circulation, replenishing blood, cooling blood, stopping bleeding, clearing away heart-fire, relieving restlessness, moistening lung, removing phlegm, replenishing vital essence, clearing away heat, promoting the secretion of saliva, dispelling wind, eliminating dampness, relieving dizziness and arresting convulsion and the like, has the advantages of rapid effectiveness, high cure rate, no toxic or side effect and high safety and convenience for treatment of meningitis, has remarkable curative effects on meningitis, and is low in price, easy to prepare and worth of wide clinical popularization and application.

Description

One is used for the treatment of meningitic medicine and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to one and be used for the treatment of meningitic medicine and preparation method.
Background technology
Meningitis is a kind of tender and lovely meninges or meninges (skim between skull and brain) infected disease.This is sick usually with the complication of antibacterial or any part of viral infection health, such as ear, hole or upper respiratory tract infection.
When suffering from meningitis, easily block narrow and small duct or stick together and cause marrowbrain circulatory disturbance, producing hydrocephalus.Be common in malpractice or treated late patient, be especially more common in neonate and young infant.Adhesive arachnoiditis is apt to occur in Foramen magnum, can hinder cerebrospinal fluid circulation; Or ependymitis forms adhesion, is the common reason causing obstructive hydrocephalus.
Except because of vomiting, frequently the reason such as to enter and can cause water and rock-soil coupling except, be also shown in brain hyponatremia, occur that mistake is slept, faint from fear, go into a coma, the symptom such as edema, whole body weakness, extremity Tendon defection, oliguria.Its occurring principle affects posthypophysis with infection, makes antidiuretic hormone secretion too much cause water retention relevant.
Because brain material injury and adhesion can make cranial nerve get involved or occur quadriplegia, also can occur the scorching and secondary epilepsy of brain abscess, entocranial artery dry what.Fulminant type epidemic encephalitis can occur together DIC, shock.In addition, otitis media, pneumonia, arthritis also occasionally can occur.
Bacteria type meningitis is that a kind of disease of especially severe needs treatment in time.If treatment is not in time, may be dead or cause permanent brain injury within a few hours.The then relatively serious but most people of virus type meningitis can recover completely, and minority leaves over sequela.
The meningitic method of current treatment mainly conventional therapy, conventional therapy is mainly based on Drug therapy, and again based on Western medicine in Drug therapy, and Western medicine has very strong side effect, have a strong impact on physical and mental health and the rehabilitation of people, therefore simple Drug therapy can not meet the requirement of patient.For this reason, we are badly in need of developing a kind of medicine and help patient and break away from the misery that meningitis brings.
Summary of the invention
The invention provides one and be used for the treatment of meningitic medicine and preparation method; It is suitable that medical material compatibility chosen by medicine of the present invention, bring out the best in each other, there is eliminating fire and detoxication, blood circulation promoting and enriching, cooling blood for hemostasis, the relieving restlessness that clears away heart-fire, moistening the lung and resolving phlegm, replenishing YIN and removing heat, promote the production of body fluid, expelling wind and removing dampness, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. the effects such as arresting convulsion, for treatment meningitis have instant effect, cure rate high, have no side effect, the advantage of safe ready, significant curative effect is had to meningitis, low price, easily prepares, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
One is used for the treatment of meningitic medicine, and raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 25-45 part Rhizoma Polygonati Odorati 20-40 part Rhodobryum roseum Limpr. 18-38 part Folium ulmi pumilae 18-38 part
Radix althaeae roseae 16-36 part Radix Libanotidis buchotomensis 15-35 part Herba Gentianopsis Paludosae 14-34 part Folium Averrhoae Carambolae 13-33 part
Folium Camelliae sinensis 13-33 part Rhizoma Begoniae Fimbristipulatae 12-32 part Herba stachydis kouyangensis 12-32 part Herba Asplenii Sarelii 11-31 part
Herba Abutili 10-30 part Rhizoma Polygonati punctati 9-29 part Pulicaria insignis Drumm. 8-28 part Fructus Piperis Longi 6-26 part.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 40 portions of Rhizoma Polygonati Odorati 35 parts of Rhodobryum roseum Limpr.s 33 parts of Folium ulmi pumilaves 33 parts
Radix althaeae roseae 31 parts of Radix Libanotidis buchotomensis 30 parts of Herba Gentianopsis Paludosae 29 parts of Folium Averrhoae Carambolae 28 parts
Folium Camelliae sinensis 28 parts of Rhizoma Begoniae Fimbristipulataes 27 parts of Herba stachydis kouyangensiss 27 parts of Herba Asplenii Sareliis 26 parts
Herba Abutili 25 parts of Rhizoma Polygonati punctati 24 parts of Pulicaria insignis Drumm. 23 parts of Fructus Piperis Longi 21 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 35 portions of Rhizoma Polygonati Odorati 30 parts of Rhodobryum roseum Limpr.s 28 parts of Folium ulmi pumilaves 28 parts
Radix althaeae roseae 26 parts of Radix Libanotidis buchotomensis 25 parts of Herba Gentianopsis Paludosae 24 parts of Folium Averrhoae Carambolae 23 parts
Folium Camelliae sinensis 23 parts of Rhizoma Begoniae Fimbristipulataes 22 parts of Herba stachydis kouyangensiss 22 parts of Herba Asplenii Sareliis 21 parts
Herba Abutili 20 parts of Rhizoma Polygonati punctati 19 parts of Pulicaria insignis Drumm. 18 parts of Fructus Piperis Longi 16 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 30 portions of Rhizoma Polygonati Odorati 25 parts of Rhodobryum roseum Limpr.s 23 parts of Folium ulmi pumilaves 23 parts
Radix althaeae roseae 21 parts of Radix Libanotidis buchotomensis 20 parts of Herba Gentianopsis Paludosae 19 parts of Folium Averrhoae Carambolae 18 parts
Folium Camelliae sinensis 18 parts of Rhizoma Begoniae Fimbristipulataes 17 parts of Herba stachydis kouyangensiss 17 parts of Herba Asplenii Sareliis 16 parts
Herba Abutili 15 parts of Rhizoma Polygonati punctati 14 parts of Pulicaria insignis Drumm. 13 parts of Fructus Piperis Longi 11 parts.
Be used for the treatment of a preparation method for meningitic medicine, comprise following processing step:
(1) Herba Euonymi Bungeani, Rhizoma Polygonati Odorati are immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pours in pot, and slow fire parch, after cooling, is smashed to pieces and ground into powder, crosses 160 order fine powders, for subsequent use;
(2) Rhodobryum roseum Limpr., Folium ulmi pumilae, Herba Gentianopsis Paludosae, Folium Averrhoae Carambolae, Folium Camelliae sinensis, Rhizoma Begoniae Fimbristipulatae, Herba stachydis kouyangensis, Rhizoma Polygonati punctati, Pulicaria insignis Drumm. and Fructus Piperis Longi are put into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge three extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) by Radix althaeae roseae, Radix Libanotidis buchotomensis and Herba Abutili decontamination, dry, smash to pieces and grind into powder, cross 180 order fine powders, for subsequent use;
(4) getting Herba Asplenii Sarelii enters to burn burnt, dry in the air cool after, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(5) by fine powder obtained to step (1), step (3) and step (4) and the obtained dry extract mixing of step (2), make tablet, be and be of the present inventionly used for the treatment of meningitic medicine.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Euonymi Bungeani: bitter in the mouth, pungent, cool in nature; Return liver,spleen,kidney warp.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Main air wet arthritis, lumbago, traumatic injury wound is swollen, thromboangiitis obliterans, lung abscess, epistaxis, furuncle toxic swelling." Zhejiang conventional medical herbs among the people " carries: " eliminating inflammation and expelling toxin, wind-damp dispelling are invigorated blood circulation, the kidney invigorating.”
Rhizoma Polygonati Odorati: sweet in the mouth, property is put down; Attach to the lung and stomach meridians.Nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Main cough caused by dryness, chronic cough, the dry throat and mouth of calentura cloudy liquid consumption wound, interior-heat is quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizzy, muscle arteries and veins spasm and pain." property of medicine opinion " carries: " disease cold and heat time main, interior tonifying for the deficiency, removes asthenia exopathogenic heat, and headache is uneasy.”
Rhodobryum roseum Limpr.: lightly seasoned, micro-hardship, property is put down; GUIXIN warp.Nourish heart, calm the nerves, calm.Main heart disease, nervous, severe palpitation, neurasthenia." choosing of Simao, Yunnan Chinese herbal medicine " carries: " calmness of calming the nerves.Control nervous, cardiopalmus, heart disease.”
Folium ulmi pumilae: sweet in the mouth, property is put down.Clearing away heat and promoting diuresis, calms the nerves, expelling phlegm for arresting cough.Main edema, dysuria, stranguria caused by urinary stone, turbid urine, insomnia, summer-heat is stranded vexed, and abundant expectoration is coughed, wine (looking into skin) nose." Treatise on Dietetic Therapy " carries: " diuresis, main stranguria caused by urinary stone.”
Radix althaeae roseae: sweet in the mouth, salty, cold nature; GUIXIN, lung, large intestine, urinary bladder channel.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, removing toxic substances and promoting pus discharge.Main stranguria, leukorrhagia, dysentery, spits blood, metrorrhagia, traumatic hemorrhage, sore swollen toxin, scalds and burns.Supplement to the Herbal carries: " root and stem, and host and guest is hot, diuresis, loose pus and blood dislikes juice.”
Radix Libanotidis buchotomensis: acrid in the mouth, sweet, warm in nature.Deliver cold expelling, expelling wind and removing dampness, reducing swelling and alleviating pain.Main anemofrigid cold, headache, toothache, rheumatic arthralgia, rheumatic arthralgia, muscles and bones is numb, and traumatic injury wound is swollen." Shaanxi Chinese herbal medicine " carries: " dispersing wind-cold, wind-damp dispelling, analgesia, strengthening the spleen and stomach, cough-relieving, removing toxic substances.Cure cold wind and cold, general aching, cough, headache, and toothache, arthralgia, traumatic injury, rheumatism bones and muscles pain, numbness, Radix Aconiti Taipeici is poisoning.”
Herba Gentianopsis Paludosae: bitter in the mouth, cold in nature; GUIXIN, Liver Channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Main fever caused by exogenous pathogens, hepatitis, cholecystitis, headache conjunctival congestion, wound swells and ache, furuncle toxic swelling.
Folium Averrhoae Carambolae: puckery, hardship, cold in nature; Return liver, spleen channel.Expelling wind and removing dampness, heat-clearing and toxic substances removing, pain relieving.Main anemopyretic cold, dysuria, puerperal edema, swollen ulcer drug, dermatitis rhus, treating swelling and pain by traumatic injury." south of the Five Ridges gather medicinal herbs record " carries: " mash deposited skin ulcer, pain relieving, heat radiation poison, hemostasis, draws out the pus, granulation promoting.”
Folium Camelliae sinensis: bitter in the mouth, sweet, cool in nature; GUIXIN, lung, stomach, liver,spleen,kidney warp.Refresh oneself, relieving thirst and restlessness, eliminates indigestion and phlegm, and diuresis is detoxified.Main headache, blurred vision, conjunctival congestion, kind sleeping of sleeping, flu, restlessness and thirst, food stagnation, halitosis, phlegm dyspnea, epilepsy, dysuria, dysentery, larynx swells, skin infection furuncle intestinal, burn due to hot liquid or fire more." daily book on Chinese herbal medicine " carries: " relieving restlessness is quenched the thirst, and separates greasy clear god.Drink is decocted in stir-fry, controls pyretic toxicity dysentery with red and white feces; Drink is decocted, only headache with rhizome of chuanxiong Qiong, Bulbus Allii Fistulosi." modern medicine study confirmation, Folium Camelliae sinensis preserved material or decoct, in test tube, all have antibacterial action to various dysentery bacterium, and its inhibitory potency is equally matched with Rhizoma Coptidis.
Rhizoma Begoniae Fimbristipulatae: sweet in the mouth, cool in nature.Clearing away heat and cooling blood, relieving cough and resolving phlegm, removing toxic substances and promoting subsidence of swelling.Main exogenous high fever, heatstroke, cough due to lung-heat, laryngopharynx swelling and pain, furuncle, scrofula, scabies, burn and scald, traumatic injury stasis of blood pain." the practical Chinese herbal medicine in Guangxi newly selects " carries: " removing heat from blood and promoting blood circulation, anti-inflammatory analgetic.Cure mainly spitting of blood, abdominal pain due to blood stasis, bruise, fracture, burn, tinea scabies.”
Herba stachydis kouyangensis: lightly seasoned, micro-hardship, cool in nature; Return spleen, heart channel.Antiinflammatory, removing toxic substances, evacuation of pus.Cure mainly furuncle, osteomyelitis." Yunnan Chinese herbal medicine " carries: " eliminating inflammation and expelling toxin is drawn out the pus.Control furuncle, osteomyelitis, mash deposited affected part with fresh grass.”
Herba Asplenii Sarelii: bitter in the mouth, cold in nature; Return gallbladder, stomach warp.Heat-clearing and toxic substances removing, evacuation of pus is subsided a swelling.Main infection, laryngopharynx swelling and pain, all high carbuncle sore swell." Hunan medicine will " carries: " hemostasia and promoting granulation, eliminating inflammation and expelling toxin.”
Herba Abutili: bitter in the mouth, property is put down; Return spleen, stomach warp.Clearing away heat-damp and promoting diuresis, removing toxic substances is had one's ideas straightened out.Main dysentery, otitis media, tinnitus, deaf, orchitis, suppurative tonsillitis, swollen ulcer drug." Chinese herbal medicine is commonly used in Shanghai " carries: " herb: removing toxic substances, dispels the wind.Control dysentery, otitis media, tinnitus, deaf, joint aches.”
Rhizoma Polygonati punctati: sweet in the mouth, hardship, property is put down; Return spleen channel.Spleen reinforcing benefit blood, removing toxicity for eliminating carbuncles.Main insufficiency of the spleen insufficiency of blood, dizzy few food, fatigue and weakness, swollen ulcer drug.
Pulicaria insignis Drumm.: bitter in the mouth, cold in nature.Anti-inflammatory analgetic, clearing away heat from blood, dispel the wind poison.Control various inflammation, anthrax, erysipelas.
Fructus Piperis Longi: acrid in the mouth, hot in nature; Return spleen, stomach, large intestine, lung, bladder, liver, kidney channel.Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.Main coldness and pain in the epigastrium, vomiting, has loose bowels, headache, toothache, nasal sinusitis, angina pectoris." detailed outline " carries: " Fructus Piperis Longi is headache, nasal sinusitis, toothache key medicine, gets it and hotly can enter Yangming Channel and to fall apart superficial heat." modern medicine study confirmation, the quintessence oil proposed in Fructus Piperis Longi all has inhibitory action to white and staphylococcus aureus and bacillus subtilis, Bacillus cereus, escherichia coli, dysentery bacterium etc.
The present invention compared with prior art, has following beneficial effect:
It is suitable that medical material compatibility chosen by medicine of the present invention, bring out the best in each other, there is eliminating fire and detoxication, blood circulation promoting and enriching, cooling blood for hemostasis, the relieving restlessness that clears away heart-fire, moistening the lung and resolving phlegm, replenishing YIN and removing heat, promote the production of body fluid, expelling wind and removing dampness, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. the effects such as arresting convulsion, for treatment meningitis have instant effect, cure rate high, have no side effect, the advantage of safe ready, significant curative effect is had to meningitis, low price, easily prepares, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Herba Euonymi Bungeani 43g Rhizoma Polygonati Odorati 39g Rhodobryum roseum Limpr. 37g Folium ulmi pumilae 37g
Radix althaeae roseae 35g Radix Libanotidis buchotomensis 34g Herba Gentianopsis Paludosae 33g Folium Averrhoae Carambolae 32g
Folium Camelliae sinensis 32g Rhizoma Begoniae Fimbristipulatae 30g Herba stachydis kouyangensis 30g Herba Asplenii Sarelii 29g
Herba Abutili 29g Rhizoma Polygonati punctati 28g Pulicaria insignis Drumm. 27g Fructus Piperis Longi 25g.
The preparation method of medicine of the present invention, comprises following processing step:
(1) Herba Euonymi Bungeani, Rhizoma Polygonati Odorati are immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pours in pot, and slow fire parch, after cooling, is smashed to pieces and ground into powder, crosses 160 order fine powders, for subsequent use;
(2) Rhodobryum roseum Limpr., Folium ulmi pumilae, Herba Gentianopsis Paludosae, Folium Averrhoae Carambolae, Folium Camelliae sinensis, Rhizoma Begoniae Fimbristipulatae, Herba stachydis kouyangensis, Rhizoma Polygonati punctati, Pulicaria insignis Drumm. and Fructus Piperis Longi are put into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge three extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) by Radix althaeae roseae, Radix Libanotidis buchotomensis and Herba Abutili decontamination, dry, smash to pieces and grind into powder, cross 180 order fine powders, for subsequent use;
(4) getting Herba Asplenii Sarelii enters to burn burnt, dry in the air cool after, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(5) by fine powder obtained to step (1), step (3) and step (4) and the obtained dry extract mixing of step (2), make tablet, be and be of the present inventionly used for the treatment of meningitic medicine.
Usage and dosage: oral, every day 3 times, each 2, within 7 days, be a course for the treatment of, 2 to 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Herba Euonymi Bungeani 40g Rhizoma Polygonati Odorati 35g Rhodobryum roseum Limpr. 33g Folium ulmi pumilae 33g
Radix althaeae roseae 31g Radix Libanotidis buchotomensis 30g Herba Gentianopsis Paludosae 29g Folium Averrhoae Carambolae 28g
Folium Camelliae sinensis 28g Rhizoma Begoniae Fimbristipulatae 27g Herba stachydis kouyangensis 27g Herba Asplenii Sarelii 26g
Herba Abutili 25g Rhizoma Polygonati punctati 24g Pulicaria insignis Drumm. 23g Fructus Piperis Longi 21g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Herba Euonymi Bungeani 35g Rhizoma Polygonati Odorati 30g Rhodobryum roseum Limpr. 28g Folium ulmi pumilae 28g
Radix althaeae roseae 26g Radix Libanotidis buchotomensis 25g Herba Gentianopsis Paludosae 24g Folium Averrhoae Carambolae 23g
Folium Camelliae sinensis 23g Rhizoma Begoniae Fimbristipulatae 22g Herba stachydis kouyangensis 22g Herba Asplenii Sarelii 21g
Herba Abutili 20g Rhizoma Polygonati punctati 19g Pulicaria insignis Drumm. 18g Fructus Piperis Longi 16g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Herba Euonymi Bungeani 30g Rhizoma Polygonati Odorati 25g Rhodobryum roseum Limpr. 23g Folium ulmi pumilae 23g
Radix althaeae roseae 21g Radix Libanotidis buchotomensis 20g Herba Gentianopsis Paludosae 19g Folium Averrhoae Carambolae 18g
Folium Camelliae sinensis 18g Rhizoma Begoniae Fimbristipulatae 17g Herba stachydis kouyangensis 17g Herba Asplenii Sarelii 16g
Herba Abutili 15g Rhizoma Polygonati punctati 14g Pulicaria insignis Drumm. 13g Fructus Piperis Longi 11g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the meningitic medicine for the treatment of, select the routine clinical observation of meningitis patient 100 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 50 example, wherein male 25 example, women 25 example, age 14-68 year, 35 years old mean age, the course of disease 1 year-8 years; Matched group 50 example, wherein male 25 example, women 25 example, age 25-70 year, 38 years old mean age, the course of disease course of disease 1 year-8 years.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes medicine of the present invention, every day 3 times, each 2, and warm water delivery service in half an hour after meal 7 days is a course for the treatment of, takes 2 to 3 courses for the treatment of continuously, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes TONGBI PIAN, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: transference cures such as generating heat, have a headache, vomit, be drowsiness, physical recovery is normal.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 38 examples, effective 9 examples, invalid 3 examples, cure rate is 76%, total effective rate 94%.
Cure 10 examples in matched group, effective 19 examples, invalid 21 examples, cure rate is 20%, total effective rate 58%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Bao, female, 60 years old, retired worker, From Shandong Rizhao people.Patient, because occurring that heating, headache, vomiting, spirit are poor, the symptom such as to become thin, is sent to my institute medical, is diagnosed as meningitis after inspection.After take 3 courses for the treatment of of medicine of the present invention after, above-mentioned symptom alleviates; Continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, and follows up a case by regular visits to and does not recur, thoroughly cure.
2, Hao, man, 48 years old, civil servant, people from Hefei ,Anhui.Patient suffers from meningitis more than 2 years, after local hospital is treated, does not take a favorable turn.For further diagnosis and treatment, to our hospital.After take 2 courses for the treatment of of medicine of the present invention, health starts to take a turn for the better; Continue to take 2 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur, thoroughly cure.
3, Zhao, female, 38 years old, teacher, Quanzhou, Fujian people.Patient found meningitis before 2 years, carries out diagnosis and treatment, do not take a favorable turn in Duo Jia hospital, introduced to our hospital through friend.After take 2 courses for the treatment of of medicine of the present invention, health takes a turn for the better, and after continuing to take 2 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
4, in certain, man, 26 years old, security personnel, people from Changsha.Patient has a high fever lasting 3 days, and with ear and upper respiratory tract infection, to our hospital, be diagnosed as meningitis by checking.After take 2 courses for the treatment of of medicine of the present invention, hyperpyrexia is moved back, and ear and upper respiratory tract infection symptoms alleviate; Continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom all disappears, and follows up a case by regular visits to and does not recur, and thoroughly cures.
5, Yao, man, 18 years old, student, Zhengzhou, henan people.Patient is to our hospital because there is the symptoms such as headache, Nausea and vomiting, rhinorrhea, pharyngalgia, is diagnosed as meningitis by checking.After take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better; After continuing to take 3 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
6, Liu, female, 8 years old, student, Shantou, Guangdong people.There is projection hyperpyrexia without obvious inducement in patient, thermal spike hyperpyrexia reaches 40.2 DEG C, and the tired behaviour of companion is uneasy, vomiting.Then give me institute to go to a doctor, physical examination is diagnosed as purulent meningitis.After taking 2 courses for the treatment of of medicine of the present invention, pick body; After continuing to take 2 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur, thoroughly cure.

Claims (5)

1. be used for the treatment of a meningitic medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 25-45 part Rhizoma Polygonati Odorati 20-40 part Rhodobryum roseum Limpr. 18-38 part Folium ulmi pumilae 18-38 part
Radix althaeae roseae 16-36 part Radix Libanotidis buchotomensis 15-35 part Herba Gentianopsis Paludosae 14-34 part Folium Averrhoae Carambolae 13-33 part
Folium Camelliae sinensis 13-33 part Rhizoma Begoniae Fimbristipulatae 12-32 part Herba stachydis kouyangensis 12-32 part Herba Asplenii Sarelii 11-31 part
Herba Abutili 10-30 part Rhizoma Polygonati punctati 9-29 part Pulicaria insignis Drumm. 8-28 part Fructus Piperis Longi 6-26 part.
2. one according to claim 1 is used for the treatment of meningitic medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 40 portions of Rhizoma Polygonati Odorati 35 parts of Rhodobryum roseum Limpr.s 33 parts of Folium ulmi pumilaves 33 parts
Radix althaeae roseae 31 parts of Radix Libanotidis buchotomensis 30 parts of Herba Gentianopsis Paludosae 29 parts of Folium Averrhoae Carambolae 28 parts
Folium Camelliae sinensis 28 parts of Rhizoma Begoniae Fimbristipulataes 27 parts of Herba stachydis kouyangensiss 27 parts of Herba Asplenii Sareliis 26 parts
Herba Abutili 25 parts of Rhizoma Polygonati punctati 24 parts of Pulicaria insignis Drumm. 23 parts of Fructus Piperis Longi 21 parts.
3. one according to claim 1 is used for the treatment of meningitic medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 35 portions of Rhizoma Polygonati Odorati 30 parts of Rhodobryum roseum Limpr.s 28 parts of Folium ulmi pumilaves 28 parts
Radix althaeae roseae 26 parts of Radix Libanotidis buchotomensis 25 parts of Herba Gentianopsis Paludosae 24 parts of Folium Averrhoae Carambolae 23 parts
Folium Camelliae sinensis 23 parts of Rhizoma Begoniae Fimbristipulataes 22 parts of Herba stachydis kouyangensiss 22 parts of Herba Asplenii Sareliis 21 parts
Herba Abutili 20 parts of Rhizoma Polygonati punctati 19 parts of Pulicaria insignis Drumm. 18 parts of Fructus Piperis Longi 16 parts.
4. one according to claim 1 is used for the treatment of meningitic medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Euonymi Bungeani 30 portions of Rhizoma Polygonati Odorati 25 parts of Rhodobryum roseum Limpr.s 23 parts of Folium ulmi pumilaves 23 parts
Radix althaeae roseae 21 parts of Radix Libanotidis buchotomensis 20 parts of Herba Gentianopsis Paludosae 19 parts of Folium Averrhoae Carambolae 18 parts
Folium Camelliae sinensis 18 parts of Rhizoma Begoniae Fimbristipulataes 17 parts of Herba stachydis kouyangensiss 17 parts of Herba Asplenii Sareliis 16 parts
Herba Abutili 15 parts of Rhizoma Polygonati punctati 14 parts of Pulicaria insignis Drumm. 13 parts of Fructus Piperis Longi 11 parts.
5. the preparation method being used for the treatment of meningitic medicine as described in claim 1-4, is characterized in that: comprise following processing step:
(1) Herba Euonymi Bungeani, Rhizoma Polygonati Odorati are immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pours in pot, and slow fire parch, after cooling, is smashed to pieces and ground into powder, crosses 160 order fine powders, for subsequent use;
(2) Rhodobryum roseum Limpr., Folium ulmi pumilae, Herba Gentianopsis Paludosae, Folium Averrhoae Carambolae, Folium Camelliae sinensis, Rhizoma Begoniae Fimbristipulatae, Herba stachydis kouyangensis, Rhizoma Polygonati punctati, Pulicaria insignis Drumm. and Fructus Piperis Longi are put into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge three extracting solution, filter, obtain filtrate, be condensed into dry extract for subsequent use;
(3) by Radix althaeae roseae, Radix Libanotidis buchotomensis and Herba Abutili decontamination, dry, smash to pieces and grind into powder, cross 180 order fine powders, for subsequent use;
(4) getting Herba Asplenii Sarelii enters to burn burnt, dry in the air cool after, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(5) by fine powder obtained to step (1), step (3) and step (4) and the obtained dry extract mixing of step (2), make tablet, be and be of the present inventionly used for the treatment of meningitic medicine.
CN201410522617.XA 2014-10-04 2014-10-04 Medicament for treating meningitis and preparation method thereof Pending CN104288497A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758625A (en) * 2015-04-25 2015-07-08 万素芹 Medicine used for treating vestibular neuritis and preparation method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101940727A (en) * 2009-07-03 2011-01-12 王学文 Chinese medicinal preparation for treating epidemic meningitis
CN103070902A (en) * 2012-12-24 2013-05-01 唐雅蓉 Drug for curing epidemic meningitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101940727A (en) * 2009-07-03 2011-01-12 王学文 Chinese medicinal preparation for treating epidemic meningitis
CN103070902A (en) * 2012-12-24 2013-05-01 唐雅蓉 Drug for curing epidemic meningitis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758625A (en) * 2015-04-25 2015-07-08 万素芹 Medicine used for treating vestibular neuritis and preparation method

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