CN103877336B - A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain - Google Patents
A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain Download PDFInfo
- Publication number
- CN103877336B CN103877336B CN201410158829.4A CN201410158829A CN103877336B CN 103877336 B CN103877336 B CN 103877336B CN 201410158829 A CN201410158829 A CN 201410158829A CN 103877336 B CN103877336 B CN 103877336B
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- chinese medicine
- traditional chinese
- fructus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain, belong to the field of Chinese medicines; The raw material of Traditional Chinese medicine lozenge effective ingredient of the present invention consists of: Herba Pteridis Multifidae, Rhizoma Polygoni Cuspidati, Fructus Seu Folium Kopsiae Officinalis, Lindera megaphylla, Herba Sonchi Oleracei, Ovum Gallus domesticus crusta, Cephalanthera falcata (Thunb) Lindl, Herba Corydalis tomentellae, Flos Lonicerae, Fructus Aristolochiae Kwangsiensis, Herba Polygalae Japonicae, Fructus Trichosanthis, Bulbus Lloydiae tibeticae, Auricled Hedyotis Herb, mountain standing grain string and Rhizoma Cimicifugae; Selected by Traditional Chinese medicine lozenge of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of reducing phlegm and fever, dispelling wind and heat pathogens, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, the resistance against diseases of effective raising body, for laryngopharynx swelling and pain, there is significant curative effect, safe without toxic side effect, the object for the treatment of both the principal and secondary aspects of a disease can be reached, fundamentally remove the misery of patient, with low cost, should be widely promoted application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain.
Background technology
Throat pain is a kind of modal disease, and it is mainly in the cold season in 1 year, and flu, tonsillitis, sinusitis, pertussis, pharyngolaryngitis and viral infection are usually all with throat pain.Most acute sore throat pain automatically can disappear within a couple of days to several weeks; But, if pain lasts exists or increased the weight of in several days, then need to see the doctor.Because if do not treated for a long time, this disease may cause rheumatic fever, harm heart and kidney.The material of any stimulation throat and oral mucosa all may cause throat pain, comprise virus, bacteriological infection, anaphylaxis, dust, medicated cigarette, waste gas, hot beverage or food, tooth or gingival infection also can involve that throat, chronic cough, bone-dry environment, regurgitation of gastric juice and sound of speaking are excessive can stimulate throat equally sometimes, and hoarseness is common side effect.
Acute pharyngitis is one of pharyngeal commonly encountered diseases, and main cause is Hemolytic streptococcus, Diplococcus pneumoniae or viral infection.Acute pharyngitis is a part for acute upper respiratory tract infection sometimes, exists with acute tonsillitis, acute rhinitis, acute laryngitis simultaneously.Sometimes acute pharyngitis is the prodrome of some acute infectious disease, such as measles, pertussis, scarlet fever etc.Main clinical manifestation is pharyngeal drying, burning sensation and through micro-pain, the pain increased subsequently, and when swallowing, pain increases the weight of, usually with general malaise, aversion to cold, heating, headache and extremities aching pain.Pharyngeal congestion during inspection, or have thick secretions, cervical lymph node tenderness, leukocyte increases.
Acute tonsillitis is a kind of commonly encountered diseases.Etiological is the infection of beta hemolytic streptococcus or other staphylococcuses or Diplococcus pneumoniae, symptoms of varying severity, general malaise, aversion to cold, heating, headache, extremities aching pain, pharyngalgia, lower neck lymph node swell and ache, check that visible pharyngeal congestion, tonsil are red and swollen, or there is purulent secretion on surface, cervical lymph node tenderness, sometimes concurrent peritonsillitis or abscess or complicated with acute rheumatic fever, myocarditis, nephritis and arthritis.Peritonsillar abscess great majority are secondary to acute tonsillitis, are especially more common in chronic tonsillitis recurrent exerbation person.Its symptom is similar to acute tonsillitis, but comparatively serious, and pharyngalgia is limited to side, and when swallowing, pain increases the weight of, and to the radiation of homonymy ear, after abscess is formed; Whole body and local symptom increase the weight of, and pharyngeal pain increases the weight of, dysphagia, language are ambiguous, difficulty in opening mouth, notably gnathospasma, and patient is face of acute ill, head deflection Ipsilateral, restriction of neck motion, palpus lymphadenectasis under Ipsilateral, and have tenderness.Acute laryngitis is the acute inflammation of larynx mucosa, and be one of common respiratory tract samples illness, cardinal symptom is hoarseness, apasm of coughing, dyspnea, and has sore throat when pronouncing and cough.Adult's General Symptoms is slight, without generating heat or having low grade fever.
At present, the Chinese medicine and western medicine for the treatment of laryngopharynx swelling and pain is various in style, large multi-component complex, and preparation technology's difficulty is large, although all have certain curative effect, therapeutic effect is not thorough, also easily recurrence after curing, and therapeutic domain is narrow, medicine time is long, can not reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The invention provides a kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain; Selected by Traditional Chinese medicine lozenge of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of reducing phlegm and fever, dispelling wind and heat pathogens, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, the resistance against diseases of effective raising body, for laryngopharynx swelling and pain, there is significant curative effect, safe without toxic side effect, the object for the treatment of both the principal and secondary aspects of a disease can be reached, fundamentally remove the misery of patient, with low cost, should be widely promoted application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Traditional Chinese medicine lozenge for laryngopharynx swelling and pain, raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 52 ~ 76 parts of Rhizoma Polygoni Cuspidati 50 ~ 74 parts of Fructus Seu Folium Kopsiae Officinalis 46 ~ 70 parts of Lindera megaphyllas 46 ~ 70 parts
Herba Sonchi Oleracei 44 ~ 68 parts of Ovum Gallus domesticus crustas 43 ~ 67 parts of Cephalanthera falcata (Thunb) Lindl 43 ~ 67 parts of Herba Corydalis tomentellaes 41 ~ 65 parts
Flos Lonicerae 40 ~ 64 parts of Fructus Aristolochiae Kwangsiensiss 40 ~ 64 parts of Herba Polygalae Japonicae 38 ~ 62 parts of Fructus Trichosanthiss 36 ~ 60 parts
Bulbus Lloydiae tibeticae 32 ~ 56 parts of Auricled Hedyotis Herbs 31 ~ 55 parts of mountain standing grain strings 27 ~ 51 parts of Rhizoma Cimicifugaes 23 ~ 47 parts.
Raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 55 ~ 71 parts of Rhizoma Polygoni Cuspidati 53 ~ 69 parts of Fructus Seu Folium Kopsiae Officinalis 49 ~ 65 parts of Lindera megaphyllas 49 ~ 65 parts
Herba Sonchi Oleracei 48 ~ 64 parts of Ovum Gallus domesticus crustas 47 ~ 63 parts of Cephalanthera falcata (Thunb) Lindl 47 ~ 63 parts of Herba Corydalis tomentellaes 45 ~ 61 parts
Flos Lonicerae 44 ~ 60 parts of Fructus Aristolochiae Kwangsiensiss 44 ~ 60 parts of Herba Polygalae Japonicae 42 ~ 58 parts of Fructus Trichosanthiss 40 ~ 56 parts
Bulbus Lloydiae tibeticae 36 ~ 52 parts of Auricled Hedyotis Herbs 35 ~ 51 parts of mountain standing grain strings 31 ~ 47 parts of Rhizoma Cimicifugaes 27 ~ 43 parts.
Raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 59 ~ 67 parts of Rhizoma Polygoni Cuspidati 57 ~ 65 parts of Fructus Seu Folium Kopsiae Officinalis 53 ~ 61 parts of Lindera megaphyllas 53 ~ 61 parts
Herba Sonchi Oleracei 52 ~ 60 parts of Ovum Gallus domesticus crustas 51 ~ 59 parts of Cephalanthera falcata (Thunb) Lindl 51 ~ 59 parts of Herba Corydalis tomentellaes 49 ~ 57 parts
Flos Lonicerae 48 ~ 56 parts of Fructus Aristolochiae Kwangsiensiss 48 ~ 56 parts of Herba Polygalae Japonicae 46 ~ 54 parts of Fructus Trichosanthiss 44 ~ 52 parts
Bulbus Lloydiae tibeticae 40 ~ 48 parts of Auricled Hedyotis Herbs 39 ~ 47 parts of mountain standing grain strings 35 ~ 43 parts of Rhizoma Cimicifugaes 31 ~ 39 parts.
Raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 63 parts of Rhizoma Polygoni Cuspidati 61 parts of Fructus Seu Folium Kopsiae Officinalis 57 parts of Lindera megaphyllas 57 parts
Herba Sonchi Oleracei 56 parts of Ovum Gallus domesticus crustas 55 parts of Cephalanthera falcata (Thunb) Lindl 55 parts of Herba Corydalis tomentellaes 53 parts
Flos Lonicerae 52 parts of Fructus Aristolochiae Kwangsiensiss 52 parts of Herba Polygalae Japonicae 50 parts of Fructus Trichosanthiss 48 parts
Bulbus Lloydiae tibeticae 44 parts of Auricled Hedyotis Herbs 43 parts of mountain standing grain strings 39 parts of Rhizoma Cimicifugaes 35 parts.
Treat a preparation method for the Traditional Chinese medicine lozenge of laryngopharynx swelling and pain, comprise following processing step:
(1) Herba Pteridis Multifidae, Herba Sonchi Oleracei and Herba Polygalae Japonicae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Rhizoma Polygoni Cuspidati, Ovum Gallus domesticus crusta and Fructus Aristolochiae Kwangsiensis are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Fructus Seu Folium Kopsiae Officinalis, Cephalanthera falcata (Thunb) Lindl and Flos Lonicerae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(4) Lindera megaphylla, Herba Corydalis tomentellae, Fructus Trichosanthis, Bulbus Lloydiae tibeticae, Auricled Hedyotis Herb and mountain standing grain string are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(5) get Rhizoma Cimicifugae removing impurity, slightly foam washing is clean, after running through, cuts sheet drying, is placed in mortar that to grind 200 order fine powders into powder for subsequent use;
(6) by juice, fine powder and the thick paste mixing obtained by above-mentioned steps (1) ~ (5), make tablet, obtain the Traditional Chinese medicine lozenge for the treatment of laryngopharynx swelling and pain of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Pteridis Multifidae: lightly seasoned, micro-hardship, cold in nature; Return large intestine, the heart, Liver Channel.Clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication; Traumatic hemorrhage is controlled in external, burn and scald." will planted by Guangxi medicine " carries: " clear large intestine, lung-heat.Control hot bloody dysentery and toothache, emesis blood.”
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature; Return liver, gallbladder, lung meridian.Heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, postnatal blood stasis does not Xia ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, traumatic injury, carbuncle sore tumefacting virus.Modern medicine study confirms, Huzhang has obvious anastalsis to traumatic hemorrhage, and for oral administration also have anastalsis to upper gastrointestinal hemorrhage; Rhizoma Polygoni Cuspidati extract has antipyretic effect, has convergence, protects from infection and antiinflammation to scald wound.
Fructus Seu Folium Kopsiae Officinalis: bitter in the mouth, pungent, warm in nature, poisonous.Anti-inflammatory analgetic, relaxing muscles and tendons and activating QI and blood in the collateral.Control pharyngolaryngitis, tonsillitis, rheumatic ostalgia, numb limbs and tense tendons.
Lindera megaphylla: acrid in the mouth, micro-hardship, warm in nature; Return liver, stomach warp.Expelling wind and removing dampness, warming middle-JIAO to promote flow of QI, reducing swelling and alleviating pain.Main air pain of dampness syndrome, numb limbs and tense tendons pain, coldness and pain in the epigastrium, hernia pain, laryngopharynx swelling and pain, tinea skin ulcer pruritus.
Herba Sonchi Oleracei: bitter in the mouth, cold in nature; GUIXIN, spleen, stomach, large intestine channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly enteritis, dysentery, jaundice, stranguria, laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, mastitis, hemorrhoid complicated by anal fistula, spit blood, epistaxis, spitting of blood, hematuria, has blood in stool, metrorrhagia.
Ovum Gallus domesticus crusta: lightly seasoned, property is put down; Return stomach, kidney channel.Control and stop drinking gastralgia, regurgitation, rickets of child, various hemorrhage, nebula of looking unfamiliar film, head body furuncle, engages discharging ear." modern Practical Chinese medicinal " carries: " roast dry grinding to the powder, boiled water takes, and controls mucosal gastritis, stomachache and rickets, pulmonary tuberculosis, bone tuberculosis etc.”
Cephalanthera falcata (Thunb) Lindl: sweet in the mouth, cold in nature; Return Liver Channel.Clearing away heat-fire, removing toxic substances.Cure mainly laryngopharynx swelling and pain, toothache, venom." Xinhua's book on Chinese herbal medicine outline " carries: " herb, has heat clearing away, the function of pathogenic fire purging.For laryngalgia, toothache.”
Herba Corydalis tomentellae: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, cool the blood dissipate blood stasis.Main influenza, laryngopharynx swelling and pain, conjunctival congestion and pain of eye, hemoptysis, spits blood, gastric heat gastralgia, hypochondriac pain due to stagnation of liverQI, damp-heat dysentery, carbuncle sore tumefacting virus, treating swelling and pain by traumatic injury.
Flos Lonicerae: sweet in the mouth, micro-hardship, cold in nature; Return lung, stomach, the heart, large intestine channel.Heat clearing away is eliminating evil, dispelling wind-heat, removing summer-heat blood poison.Modern pharmacological research shows, effective ingredient in Flos Lonicerae has antibacterial and antivirus action, obvious inhibitory action is had to staphylococcus aureus, Hemolytic streptococcus, dysentery bacterium, Bacillus typhi, meningococcus, Diplococcus pneumoniae, bacillus pyocyaneus and influenza virus etc., and can immunologic function be strengthened, antiinflammatory, antipyretic, there is obvious inhibitory action to inflammation.
Nan Xiang: bitter in the mouth, cold in nature; Return stomach warp.Heat-clearing and toxic substances removing, regulating QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral.For acute gastroenteritis, taste-blindness rate, pharyngolaryngitis, pulmonary tuberculosis, main ulcer sore pain, stomachache, abdominalgia with intestinal abscess, rheumatic arthralgia, treating swelling and pain by traumatic injury." register planted by Guangxi medicine " carries: " refrigerantly to bring down a fever, removing toxic substances.Control dizziness, laryngalgia, gastropathy, stomachache, skin ulcer scabies, knife injury, snakebite.”
Herba Polygalae Japonicae: taste is micro-pungent, slightly warm in nature.Promoting blood circulation to remove blood stasis, eliminating phlegm and relieving cough, removing toxic substances pain relieving.For pharyngitis, tonsillitis, stomatitis, cough, infantile pneumonia, infantile malnutrition, urinary system calculus, mastitis, osteomyelitis, venom is controlled in external, furuncle furuncle and phyma." illustrated handbook planted by middle traditional Chinese medicines " carries: " root is calm, expectorant, energy intelligent promoting and the mind tranquilizing, and fall apart strongly fragrant reducing phlegm, and disappears red swollen.Control bronchitis, pneumonia, cough ant phlegm, palpitation with fear, forgetful carbuncle skin ulcer swells, sore throat.”
Fructus Trichosanthis: sweet in the mouth, micro-hardship, cold in nature; Return lung, stomach, large intestine channel.Moistening the lung and resolving phlegm, eliminating stagnation laxation.Control phlegm-heat cough, the thoracic obstruction, blocked-up chest, consumptive lung disease hemoptysis, quenches one's thirst, jaundice, constipation, carbuncle from the beginning of." detailed outline " carries: " lung moistening is dry, pathogenic fire reducing.Control cough, clearing away phlegm is tied, throat, subduing inflammation sore.”
Bulbus Lloydiae tibeticae: sweet in the mouth, micro-hardship, property is put down.Expelling phlegm for arresting cough, externally used detumescence stops blooding.For cough, asthma, bronchitis; Carbuncle sore tumefacting virus is controlled in external, traumatic hemorrhage.
Auricled Hedyotis Herb: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For cold, fever, cough due to lung-heat, laryngalgia, acute conjunctivitis, enteritis, dysentery; Venom is controlled in external, traumatic injury, carbuncle pyogenic infections from tumour or sore, mastitis, eczema.
Mountain standing grain string: sweet in the mouth, micro-puckery, cool in nature.Heat clearing away, removing toxic substances, anti-inflammatory analgetic.Cure mainly acute tonsillitis, laryngitis, stomatitis, bronchitis, burn due to hot liquid or fire.
Rhizoma Cimicifugae: acrid in the mouth, sweet, cold nature; Return lung, spleen, large intestine, stomach warp.Heat-clearing and toxic substances removing, delivers rash, ascending up spleen-Qi and Yang.Cure mainly epidemic disease fire-toxin, aphtha, pharyngalgia, macule, headache cold and heat, carbuncle sore tumefacting virus, sinking of QI of middle-JIAO, diarrhea due to hypofunction of the spleen, heavy under chronic dysentery." detailed outline " carries: " it is up that Rhizoma Cimicifugae draws positive bright clearing heat in QI system, and it is up that Radix Bupleuri draws few positive clearing heat in QI system, and this is hungry full, the raw and cold internal injury of the hungry and forced labour of weak, the first deficiency of vital energy of natural endowment element, and the most key medicine of taste tying-in also." modern medicine study confirms, Rhizoma Cimicifugae extract has the effect of antibacterial, blood pressure lowering, suppression cardiac muscle, decreased heart rate, has sedation to central nervous system.
The present invention compared with prior art, has following beneficial effect:
Selected by Traditional Chinese medicine lozenge of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of reducing phlegm and fever, dispelling wind and heat pathogens, moistening the lung and resolving phlegm, lung qi dispersing cough-relieving, the resistance against diseases of effective raising body, for laryngopharynx swelling and pain, there is significant curative effect, safe without toxic side effect, the object for the treatment of both the principal and secondary aspects of a disease can be reached, fundamentally remove the misery of patient, with low cost, should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Traditional Chinese medicine lozenge effective ingredient of the present invention and weight are:
Herba Pteridis Multifidae 71g Rhizoma Polygoni Cuspidati 69g Fructus Seu Folium Kopsiae Officinalis 65g Lindera megaphylla 65g
Herba Sonchi Oleracei 64g Ovum Gallus domesticus crusta 63g Cephalanthera falcata (Thunb) Lindl 63g Herba Corydalis tomentellae 61g
Flos Lonicerae 60g Fructus Aristolochiae Kwangsiensis 60g Herba Polygalae Japonicae 58g Fructus Trichosanthis 56g
Bulbus Lloydiae tibeticae 52g Auricled Hedyotis Herb 51g mountain standing grain string 47g Rhizoma Cimicifugae 43g.
Treat a preparation method for the Traditional Chinese medicine lozenge of laryngopharynx swelling and pain, comprise following processing step:
(1) Herba Pteridis Multifidae, Herba Sonchi Oleracei and Herba Polygalae Japonicae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Rhizoma Polygoni Cuspidati, Ovum Gallus domesticus crusta and Fructus Aristolochiae Kwangsiensis are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Fructus Seu Folium Kopsiae Officinalis, Cephalanthera falcata (Thunb) Lindl and Flos Lonicerae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(4) Lindera megaphylla, Herba Corydalis tomentellae, Fructus Trichosanthis, Bulbus Lloydiae tibeticae, Auricled Hedyotis Herb and mountain standing grain string are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(5) get Rhizoma Cimicifugae removing impurity, slightly foam washing is clean, after running through, cuts sheet drying, is placed in mortar that to grind 200 order fine powders into powder for subsequent use;
(6) by juice, fine powder and the thick paste mixing obtained by above-mentioned steps (1) ~ (5), make tablet, obtain the Traditional Chinese medicine lozenge for the treatment of laryngopharynx swelling and pain of the present invention.
Usage and dosage: buccal, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Traditional Chinese medicine lozenge effective ingredient of the present invention and weight are:
Herba Pteridis Multifidae 67g Rhizoma Polygoni Cuspidati 65g Fructus Seu Folium Kopsiae Officinalis 61g Lindera megaphylla 61g
Herba Sonchi Oleracei 60g Ovum Gallus domesticus crusta 59g Cephalanthera falcata (Thunb) Lindl 59g Herba Corydalis tomentellae 57g
Flos Lonicerae 56g Fructus Aristolochiae Kwangsiensis 56g Herba Polygalae Japonicae 54g Fructus Trichosanthis 52g
Bulbus Lloydiae tibeticae 48g Auricled Hedyotis Herb 47g mountain standing grain string 43g Rhizoma Cimicifugae 39g.
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Traditional Chinese medicine lozenge effective ingredient of the present invention and weight are:
Herba Pteridis Multifidae 63g Rhizoma Polygoni Cuspidati 61g Fructus Seu Folium Kopsiae Officinalis 57g Lindera megaphylla 57g
Herba Sonchi Oleracei 56g Ovum Gallus domesticus crusta 55g Cephalanthera falcata (Thunb) Lindl 55g Herba Corydalis tomentellae 53g
Flos Lonicerae 52g Fructus Aristolochiae Kwangsiensis 52g Herba Polygalae Japonicae 50g Fructus Trichosanthis 48g
Bulbus Lloydiae tibeticae 44g Auricled Hedyotis Herb 43g mountain standing grain string 39g Rhizoma Cimicifugae 35g.
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Traditional Chinese medicine lozenge effective ingredient of the present invention and weight are:
Herba Pteridis Multifidae 59g Rhizoma Polygoni Cuspidati 57g Fructus Seu Folium Kopsiae Officinalis 53g Lindera megaphylla 53g
Herba Sonchi Oleracei 52g Ovum Gallus domesticus crusta 51g Cephalanthera falcata (Thunb) Lindl 51g Herba Corydalis tomentellae 49g
Flos Lonicerae 48g Fructus Aristolochiae Kwangsiensis 48g Herba Polygalae Japonicae 46g Fructus Trichosanthis 44g
Bulbus Lloydiae tibeticae 40g Auricled Hedyotis Herb 39g mountain standing grain string 35g Rhizoma Cimicifugae 31g.
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Traditional Chinese medicine lozenge effective ingredient of the present invention and weight are:
Herba Pteridis Multifidae 55g Rhizoma Polygoni Cuspidati 53g Fructus Seu Folium Kopsiae Officinalis 49g Lindera megaphylla 49g
Herba Sonchi Oleracei 48g Ovum Gallus domesticus crusta 47g Cephalanthera falcata (Thunb) Lindl 47g Herba Corydalis tomentellae 45g
Flos Lonicerae 44g Fructus Aristolochiae Kwangsiensis 44g Herba Polygalae Japonicae 42g Fructus Trichosanthis 40g
Bulbus Lloydiae tibeticae 36g Auricled Hedyotis Herb 35g mountain standing grain string 31g Rhizoma Cimicifugae 27g.
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Traditional Chinese medicine lozenge for the treatment of laryngopharynx swelling and pain, select the routine clinical observation of laryngopharynx swelling and pain patient 382 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 191 example, wherein male 95 example, women 96 example, 20 ~ 67 years old age, 43.5 years old mean age, average 3.1 years of the course of disease; Matched group 191 example, wherein male 96 example, women 95 example, 21 ~ 66 years old age, 43.5 years old mean age, average 2.9 years of the course of disease.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Traditional Chinese medicine lozenge of the present invention, buccal, every day 2 times, each 1 time sooner or later, each 1 (every sheet 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes cefadroxil, oral, adult's 1g ~ 2g/ day, divide and take for 2 times, occasionally can cause allergy, use is avoided to other cephalosporin allergy sufferers, the suitable decrement of renal insufficiency person, small number of patients has the untoward reaction such as erythra, stomachache, the diarrhoea of feeling sick, and accidental transaminase raises.
3, efficacy determination:
(1) cure: laryngopharynx swelling and pain symptom all disappears, test chamber inspection recovers normal.
(2) effective: laryngopharynx swelling and pain symptom is obviously alleviated, test chamber inspection takes a turn for the better to some extent.
(3) effective: laryngopharynx swelling and pain symptom is alleviated to some extent, and test chamber inspection is clearly better.
(4) invalid: by treating rear laryngopharynx swelling and pain symptom without alleviating or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Pan, man, 21 years old, people from Dalian.Patient's pharyngalgia is generated heat, and occur pharyngalgia, heating after suffering from cold, body temperature 38 DEG C, clinic, community gives azithromycin 0.5 dead point every day once, symptom obviously alleviates for three days on end, within after drug withdrawal second day, occurs pharyngalgia again, without heating, heavy when pharyngalgia is comparatively fallen ill, and right side is obvious, water of dare not taking food.Admission examination, pharynx mucosa acute congestion, tonsil II degree of enlargement, right side palatoglossal arch swelling, slightly protuberance, take Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom is alleviated to some extent, and after continuing to take 1 course for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to so far without recurrence.
2, certain is shut out, female, 27 years old, people from Nanjing.There are pharyngalgia, low grade fever 2 days after patient suffers from cold, without cough and dyspnea, admission examination, pharynx mucosa acute congestion, uvula congestion and edema, the enlargement of pharynx rear wall lymph follicle, tonsil is little, and laryngeal mirror is shown in larynx and swallows normal, gives Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom is alleviated to some extent, after continuing to take 2 courses for the treatment of, and transference cure, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
3, remaining certain, man, 31 years old, people from Wuhu.Patient Gao Re, pharyngalgia companioned with headache, the whole body is weak, and joint aches was examined over 2 days, body temperature 39 DEG C of having a medical check-up, pharynx mucosa acute congestion, and the congested enlargement of tonsil, crypts is shown in purulent secretion.Tonsil week, laryngeal mirror was shown in epiglottis, larynx normally without protuberance, blood leukocytes sum: 15.2 medical science three bases × 109/L, neutral leaflet 0.85.Give Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom obviously alleviates, and after taking 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
4, certain is worn, female, 34 years old, Xiamen of Fujian Province people.Patient's dry cough, abundant expectoration, itching throat, pharyngalgia, red lip, and with uneasy sleeping at night, red tip of the tongue is red, tongue is white, taken Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom alleviates to some extent, after continuing to take 1 course for the treatment of, transference cure, recovery from illness.
5, the summer, man, 40 years old, Yunfu, guangdong Province people.Patient is right side pharyngalgia repeatedly, uncomfortable, foreign body sensation half a year, once presses treatment of chronic pharyngitis, without positive effect, this time pharyngalgia, with spitting of blood twice, amount is few, each 1-2 mouth is fresh blood, morbidity and with heating, without cough and expectoration, without sensation of oppression over the chest with shortness of breath, do not affect feed, have a medical check-up and see pharynx mucosa chronic congestion, tonsil not enlargement, mucosa slightly swelling below the tonsil of right side is shown in by laryngeal mirror, protuberance, mucosa is smooth, vocal cord movement is good, Pyriform sinus is symmetrical, cervical region does not touch enlarged lymph node, patient diagnosis " the other gap of pharynx infects ", broad ectrum antibiotic one week, pain relief, but swelling does not disappear, upon somebody's introduction, take Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom is alleviated to some extent, after continuing to take 2 courses for the treatment of, transference cure, recovery from illness, follow up a case by regular visits to so far without recurrence.
6, certain is appointed, female, 45 years old, zunyi, guizhou people.Patient's foreign body in pharynx sense 1 year, with pharyngeal abnormal flavour, without heating and pharyngalgia, oral antibiotic is treated, and fail to respond to any medical treatment, Hou Qu hospital haves a medical check-up: see that bilateral amygdala two degree is large, there is yellow-white granular substance at crypts place, can wipe away, without hemorrhage, take Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom obviously alleviates, after taking 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
Claims (5)
1. treat a Traditional Chinese medicine lozenge for laryngopharynx swelling and pain, it is characterized in that: raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 52 ~ 76 parts of Rhizoma Polygoni Cuspidati 50 ~ 74 parts of Fructus Seu Folium Kopsiae Officinalis 46 ~ 70 parts of Lindera megaphyllas 46 ~ 70 parts
Herba Sonchi Oleracei 44 ~ 68 parts of Ovum Gallus domesticus crustas 43 ~ 67 parts of Cephalanthera falcata (Thunb) Lindl 43 ~ 67 parts of Herba Corydalis tomentellaes 41 ~ 65 parts
Flos Lonicerae 40 ~ 64 parts of Fructus Aristolochiae Kwangsiensiss 40 ~ 64 parts of Herba Polygalae Japonicae 38 ~ 62 parts of Fructus Trichosanthiss 36 ~ 60 parts
Bulbus Lloydiae tibeticae 32 ~ 56 parts of Auricled Hedyotis Herbs 31 ~ 55 parts of mountain standing grain strings 27 ~ 51 parts of Rhizoma Cimicifugaes 23 ~ 47 parts.
2. a kind of Traditional Chinese medicine lozenge for the treatment of laryngopharynx swelling and pain according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 55 ~ 71 parts of Rhizoma Polygoni Cuspidati 53 ~ 69 parts of Fructus Seu Folium Kopsiae Officinalis 49 ~ 65 parts of Lindera megaphyllas 49 ~ 65 parts
Herba Sonchi Oleracei 48 ~ 64 parts of Ovum Gallus domesticus crustas 47 ~ 63 parts of Cephalanthera falcata (Thunb) Lindl 47 ~ 63 parts of Herba Corydalis tomentellaes 45 ~ 61 parts
Flos Lonicerae 44 ~ 60 parts of Fructus Aristolochiae Kwangsiensiss 44 ~ 60 parts of Herba Polygalae Japonicae 42 ~ 58 parts of Fructus Trichosanthiss 40 ~ 56 parts
Bulbus Lloydiae tibeticae 36 ~ 52 parts of Auricled Hedyotis Herbs 35 ~ 51 parts of mountain standing grain strings 31 ~ 47 parts of Rhizoma Cimicifugaes 27 ~ 43 parts.
3. a kind of Traditional Chinese medicine lozenge for the treatment of laryngopharynx swelling and pain according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 59 ~ 67 parts of Rhizoma Polygoni Cuspidati 57 ~ 65 parts of Fructus Seu Folium Kopsiae Officinalis 53 ~ 61 parts of Lindera megaphyllas 53 ~ 61 parts
Herba Sonchi Oleracei 52 ~ 60 parts of Ovum Gallus domesticus crustas 51 ~ 59 parts of Cephalanthera falcata (Thunb) Lindl 51 ~ 59 parts of Herba Corydalis tomentellaes 49 ~ 57 parts
Flos Lonicerae 48 ~ 56 parts of Fructus Aristolochiae Kwangsiensiss 48 ~ 56 parts of Herba Polygalae Japonicae 46 ~ 54 parts of Fructus Trichosanthiss 44 ~ 52 parts
Bulbus Lloydiae tibeticae 40 ~ 48 parts of Auricled Hedyotis Herbs 39 ~ 47 parts of mountain standing grain strings 35 ~ 43 parts of Rhizoma Cimicifugaes 31 ~ 39 parts.
4. a kind of Traditional Chinese medicine lozenge for the treatment of laryngopharynx swelling and pain according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Traditional Chinese medicine lozenge effective ingredient are:
Herba Pteridis Multifidae 63 parts of Rhizoma Polygoni Cuspidati 61 parts of Fructus Seu Folium Kopsiae Officinalis 57 parts of Lindera megaphyllas 57 parts
Herba Sonchi Oleracei 56 parts of Ovum Gallus domesticus crustas 55 parts of Cephalanthera falcata (Thunb) Lindl 55 parts of Herba Corydalis tomentellaes 53 parts
Flos Lonicerae 52 parts of Fructus Aristolochiae Kwangsiensiss 52 parts of Herba Polygalae Japonicae 50 parts of Fructus Trichosanthiss 48 parts
Bulbus Lloydiae tibeticae 44 parts of Auricled Hedyotis Herbs 43 parts of mountain standing grain strings 39 parts of Rhizoma Cimicifugaes 35 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Traditional Chinese medicine lozenge of laryngopharynx swelling and pain, it is characterized in that: comprise following processing step:
(1) Herba Pteridis Multifidae, Herba Sonchi Oleracei and Herba Polygalae Japonicae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Rhizoma Polygoni Cuspidati, Ovum Gallus domesticus crusta and Fructus Aristolochiae Kwangsiensis are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Fructus Seu Folium Kopsiae Officinalis, Cephalanthera falcata (Thunb) Lindl and Flos Lonicerae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(4) Lindera megaphylla, Herba Corydalis tomentellae, Fructus Trichosanthis, Bulbus Lloydiae tibeticae, Auricled Hedyotis Herb and mountain standing grain string are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(5) get Rhizoma Cimicifugae removing impurity, slightly foam washing is clean, after running through, cuts sheet drying, is placed in mortar that to grind 200 order fine powders into powder for subsequent use;
(6) by juice, fine powder and the thick paste mixing obtained by above-mentioned steps (1) ~ (5), make tablet, obtain the Traditional Chinese medicine lozenge of described treatment laryngopharynx swelling and pain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410158829.4A CN103877336B (en) | 2014-04-20 | 2014-04-20 | A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410158829.4A CN103877336B (en) | 2014-04-20 | 2014-04-20 | A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103877336A CN103877336A (en) | 2014-06-25 |
| CN103877336B true CN103877336B (en) | 2016-03-30 |
Family
ID=50946672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410158829.4A Expired - Fee Related CN103877336B (en) | 2014-04-20 | 2014-04-20 | A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103877336B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728983A (en) * | 2015-11-19 | 2017-05-31 | 哈尔滨圣吉药业股份有限公司 | A kind of fibert strengthening the spleen and stomach electuary and preparation method thereof |
| CN105435071A (en) * | 2015-12-25 | 2016-03-30 | 太仓新亚逊生物科技有限公司 | Traditional Chinese medicinal buccal tablet for clearing throat |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732500A (en) * | 2008-11-11 | 2010-06-16 | 戚寰 | Medicine for preventing and treating acute and chronic pharyngitis and sphagitis |
| CN102988495A (en) * | 2012-12-27 | 2013-03-27 | 江苏老蚕坊蚕桑生物科技开发有限公司 | Compound throat cool tablet |
| CN103083551A (en) * | 2013-01-24 | 2013-05-08 | 尹桂华 | Traditional Chinese medicine composition for treating infantile suppurative tonsillitis |
-
2014
- 2014-04-20 CN CN201410158829.4A patent/CN103877336B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732500A (en) * | 2008-11-11 | 2010-06-16 | 戚寰 | Medicine for preventing and treating acute and chronic pharyngitis and sphagitis |
| CN102988495A (en) * | 2012-12-27 | 2013-03-27 | 江苏老蚕坊蚕桑生物科技开发有限公司 | Compound throat cool tablet |
| CN103083551A (en) * | 2013-01-24 | 2013-05-08 | 尹桂华 | Traditional Chinese medicine composition for treating infantile suppurative tonsillitis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103877336A (en) | 2014-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103505656B (en) | Chinese medicine preparation for treating stomatitis | |
| CN104524227B (en) | A kind of Chinese medicine preparation and preparation method being used for the treatment of dental caries | |
| CN103611128A (en) | Mouth wash for preventing dental ulcer | |
| CN103877336B (en) | A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of laryngopharynx swelling and pain | |
| CN103735780B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis | |
| CN104306867A (en) | Traditional Chinese medicine preparation for curing viral myocarditis and preparation method | |
| CN104721510A (en) | Jiedu Zhitong preparation for acute pharyngitis and preparing method thereof | |
| CN103877397A (en) | Medicine for treating radiation-induced pulmonary injury and preparation method thereof | |
| CN103735773B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of tonsil inflammation | |
| CN103845718A (en) | Medicine for treating cough and asthma and preparation method thereof | |
| CN103989836A (en) | Traditional Chinese medicine preparation for treating appendicitis and preparation method thereof | |
| CN102641442B (en) | Traditional Chinese medicine preparation for treating recurrent aphthae | |
| CN103638369B (en) | Traditional Chinese medicinal preparation for treating mastitis | |
| CN105477472A (en) | Medicament for treating periodontitis | |
| CN105496924A (en) | Toothpaste for treating periodontitis | |
| CN105561007A (en) | Traditional Chinese medicine preparation for treating infantile influenza and preparation method | |
| CN104324171A (en) | Traditional Chinese medicine preparation capable of treating chronic gastritis | |
| CN103877466B (en) | A kind of medicine and preparation method for the treatment of cough with copious phlegm | |
| CN104173807A (en) | Medicament for treating virus meningitis and preparation method thereof | |
| CN103877304A (en) | Drug for treating gall-stone and preparation method thereof | |
| CN104258147A (en) | Traditional Chinese medicine preparation for treating breast liposarcoma and preparation method of traditional Chinese medicine preparation | |
| CN104288481A (en) | Traditional Chinese medicine preparation for treating wind heat type infantile bronchitis | |
| CN106075249A (en) | A kind of medicine treating periodontitis and preparation method | |
| CN107823586A (en) | A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration | |
| CN103977221A (en) | Medicine for treating capillary bronchitis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Xia Weihua Inventor before: Ci Wenxue Inventor before: Yang Xiaoping Inventor before: Zhang Jinghong |
|
| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170828 Address after: 466300 No. 5 West Ring Road, old town, Shenqiu County, Henan Patentee after: Xia Weihua Address before: The holy city of Shandong province Weifang city 262700 Street No. 98, Shouguang City, Shouguang City Hospital of traditional Chinese Medicine Patentee before: Ci Wenxue |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160330 Termination date: 20180420 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |