CN103764100A - 有机溶剂中小肾上腺素能激动剂盐形式的制剂 - Google Patents

有机溶剂中小肾上腺素能激动剂盐形式的制剂 Download PDF

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Publication number
CN103764100A
CN103764100A CN201280036959.XA CN201280036959A CN103764100A CN 103764100 A CN103764100 A CN 103764100A CN 201280036959 A CN201280036959 A CN 201280036959A CN 103764100 A CN103764100 A CN 103764100A
Authority
CN
China
Prior art keywords
preparation
vasoconstrictor
norepinephrine
skin
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280036959.XA
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English (en)
Chinese (zh)
Inventor
威廉·E·法尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PROCERTUS BIOPHARM Inc
Original Assignee
PROCERTUS BIOPHARM Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PROCERTUS BIOPHARM Inc filed Critical PROCERTUS BIOPHARM Inc
Publication of CN103764100A publication Critical patent/CN103764100A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201280036959.XA 2011-06-02 2012-03-09 有机溶剂中小肾上腺素能激动剂盐形式的制剂 Pending CN103764100A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161492664P 2011-06-02 2011-06-02
US61/492,664 2011-06-02
PCT/US2012/028446 WO2012166227A1 (en) 2011-06-02 2012-03-09 Formulation of small adrenergic agonist salt forms in organic solvents

Publications (1)

Publication Number Publication Date
CN103764100A true CN103764100A (zh) 2014-04-30

Family

ID=47259712

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280036959.XA Pending CN103764100A (zh) 2011-06-02 2012-03-09 有机溶剂中小肾上腺素能激动剂盐形式的制剂

Country Status (6)

Country Link
US (1) US20140343159A1 (https=)
EP (1) EP2713988A4 (https=)
JP (1) JP2014515400A (https=)
CN (1) CN103764100A (https=)
AU (1) AU2012262947A1 (https=)
WO (1) WO2012166227A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2990031B1 (en) * 2014-08-28 2019-11-13 Sun Pharmaceutical Industries Ltd Parenteral dosage form of norepinephrine
US9937117B2 (en) 2015-07-09 2018-04-10 Galderma S.A. Method of reducing hair loss associated with chemotherapy
WO2020148609A1 (en) * 2019-01-10 2020-07-23 Sun Pharmaceutical Industries Limited A stable aqueous injectable solution of epinephrine
CN119212680A (zh) * 2022-03-04 2024-12-27 瓦索达纳米有限公司 局部组合物和方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101198362A (zh) * 2005-06-17 2008-06-11 威斯康星校友研究基金会 在癌症化疗和放疗时保护细胞的局部血管收缩剂制品和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4643586A (en) * 1983-01-12 1987-02-17 Hansen Jens S Equipment and method for calibration of instruments having a temperature sensing unit
CA2154979A1 (en) * 1995-07-28 1997-01-29 Kenneth T. Armstrong Topical phenylephrine preparation
US7405080B2 (en) * 2000-03-23 2008-07-29 Voellmy Richard W Compositions and methods relating to prevention of chemotherapy-induced alopecia
US7229630B2 (en) * 2002-06-20 2007-06-12 Novalar Pharmaceuticals, Inc. Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof
EP1998742A2 (en) * 2006-03-08 2008-12-10 Nuviance, INC. Transdermal drug delivery compositions and topical compositions for application on the skin
EP2313037A1 (en) * 2008-06-30 2011-04-27 Oron Zachar Dermal application of vasoconstrictors
US8969331B2 (en) * 2008-10-01 2015-03-03 Roman Kelner Treatment of skin and mucosal superficial wounds using adrenergic receptor agonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101198362A (zh) * 2005-06-17 2008-06-11 威斯康星校友研究基金会 在癌症化疗和放疗时保护细胞的局部血管收缩剂制品和方法

Also Published As

Publication number Publication date
EP2713988A4 (en) 2015-03-04
US20140343159A1 (en) 2014-11-20
AU2012262947A1 (en) 2014-01-16
EP2713988A1 (en) 2014-04-09
WO2012166227A1 (en) 2012-12-06
JP2014515400A (ja) 2014-06-30

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