CN103751061B - Tomato leaf extract and the application in cosmetics - Google Patents
Tomato leaf extract and the application in cosmetics Download PDFInfo
- Publication number
- CN103751061B CN103751061B CN201410031744.XA CN201410031744A CN103751061B CN 103751061 B CN103751061 B CN 103751061B CN 201410031744 A CN201410031744 A CN 201410031744A CN 103751061 B CN103751061 B CN 103751061B
- Authority
- CN
- China
- Prior art keywords
- tomato leaf
- leaf extract
- solution
- dry
- cosmetics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention discloses a kind of tomato leaf extract and the application in cosmetics.Comprise following steps: step one, pulverizing: the tomato leaf of drying is crushed to 100 orders; Step 2, slightly extraction: the aqueous solution of preparation containing sodium sulfite, then add ethanol, obtain solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature; Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry; Step 4, dissolving are refined: add solvent at dry step 3 obtained, the mass volume ratio of dry and solvent is 1:5, stand at low temperature 1-2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.The tomato leaf extract working substance content that preparation method of the present invention obtains is high, can be added in multiple cosmetics, plays the crease-resistant effect of beauty treatment.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of tomato leaf extract and the application in cosmetics.
Background technology
Plant skin protection is the trend of rising in recent years, and cosmetics are after experienced by the chemicals in petrochemical industry source of synthesis, and nowadays back to nature, people start in natural plants, find effect thing making skin health vigor.
Fructus Lycopersici esculenti another name Fructus Lycopersici esculenti, Solanaceae Fructus Lycopersici esculenti platymiscium, originates in South America, extensively cultivates in China north and south, wherein maximum with Xinjiang output.As everyone knows, containing antioxidant contents such as vitamin in tamato fruit, be applied in cosmetics and have beauty treatment anti-wrinkle effect.But the leaf of Fructus Lycopersici esculenti is not is not fully researched and developed utilization, after annual Fruits of Tomatoes is plucked, tomato plant all will be discarded, and further not developed processing and utilization.In fact, same containing the abundant antioxidant such as vitamin C, flavone in tomato leaf, in beauty treatment anti-wrinkle cosmetic, there is good application prospect, but not yet have pertinent literature to report at present.
Summary of the invention
The object of the invention is to solve above-mentioned technical problem, a kind of tomato leaf method for preparing extractive of simple, efficient, environmental protection is provided, and the tomato leaf extract prepared is applied in cosmetics, play effect that beauty treatment is crease-resistant.
Object of the present invention is achieved through the following technical solutions:
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly extraction: the aqueous solution of preparation containing sodium sulfite, then add ethanol, obtain solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add solvent at dry step 3 obtained, the mass volume ratio of dry and solvent is 1:5, stand at low temperature 1-2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract;
Wherein in some embodiments, the described ethanol contend concentration slightly carried in the solution that step obtains is 30-50%, and described dissolving purification step stand at low temperature temperature is-10 DEG C ~ 0 DEG C.
Wherein in some embodiments, described sodium sulfite mass fraction is in aqueous 0.1-0.5%.
Sodium sulfite of the present invention, be the antioxidant that a kind of permission is directly added in cosmetics, sodium sulfite plays the effect preventing the readily oxidizable substance such as vitamin C, folic acid at high temperature oxidized in the manufacture of tomato leaf extract.Its addition selects the reason of 0.1%-0.5% to be in the present invention, the present inventor find in an experiment when sodium sulfite addition lower than 0.1% time, the antioxidant effect that rises not obvious, and when its addition higher than 0.5% time be easily separate out in the alcoholic solution of 30-50% containing volumetric concentration.
In a preferred embodiment of the invention, described solvent is one or more replacements in ethanol, propylene glycol, glycerol, PEG-4000, dipropylene glycol, 1,3 butylene glycol etc.Preferably, described solvent is 1,3 butylene glycol.
Present invention also offers the tomato leaf extract obtained by above-mentioned preparation method, in the middle of described tomato leaf extract, general flavone content >=8Wt%, Vitamin C content >=0.3Wt%.
Present invention also offers and preparing the application in cosmetics according to above-mentioned tomato leaf extract.
Wherein in some embodiments, described tomato leaf extract is preparing the application in cosmetics, comprise substrate and tomato leaf extract, described substrate is vegetable and animals oils, mineral oil, wax, higher alcohol, fatty alcohol, silicone oil, surfactant, phospholipid, alcohols, polyalcohols, water-soluble polymer, oil-soluble polymers, mineral or deionized water, and the dosage form of described cosmetics is water preparation, cream, washing liquid or emulsion.
The present invention relative to the advantage of prior art and beneficial effect is:
1, the present invention takes full advantage of natural plants, expands the Application and Development field of tomato leaf;
2, the present invention is in the process preparing tomato leaf extract, and only through filtration, dry, centrifugal, standing several process, whole extraction process is simple and easy to operate, and production cost is low; But the content of the active component in extract still reaches higher level.
3, the present invention is in leaching process, only uses water, ethanol, 1,3 butylene glycol three kinds of solvents, does not introduce other extraction organic solvent, promote that sedimentary extraction is separated out by cryogenic freezing technology, then centrifugalize, is a kind of preparation technology of environmental protection.
Detailed description of the invention
Polyacrylamide in following embodiment/C13-14 isoparaffin/laureth-7 is commercially available prod, and commodity are called SEPIGEL305, originates from match BIC Corp of France.
Below in conjunction with preferred specific embodiment, the invention will be further described.
Embodiment 1
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly to extract: preparation mass fraction is the aqueous solution of sodium bisulfite of 0.1%, then to add ethanol to ethanol contend concentration be 30%, obtains solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add 1,3 butylene glycol at dry step 3 obtained, dry and 1, the mass volume ratio of 3-butanediol is 1:5, and-10 DEG C static 2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.
Embodiment 2
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly to extract: preparation mass fraction is the aqueous solution of sodium bisulfite of 0.3%, then to add ethanol to ethanol contend concentration be 50%, obtains solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add 1,3 butylene glycol at dry step 3 obtained, dry and 1, the mass volume ratio of 3-butanediol is 1:5, and-5 DEG C static 1 day, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.
Embodiment 3
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly to extract: preparation mass fraction is the aqueous solution of sodium bisulfite of 0.5%, then to add ethanol to ethanol contend concentration be 40%, obtains solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add 1,3 butylene glycol at dry step 3 obtained, dry and 1, the mass volume ratio of 3-butanediol is 1:5, and 0 DEG C static 2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.
The performance test of embodiment 4 tomato leaf extract
One, the stability test of tomato leaf extract
Get the transparent test bottle that 6 capacity are 100g, fill the tomato leaf extract obtained by the present embodiment 1, do stability test in room temperature (20 ± 1) DEG C, heat-resisting (45 ± 1) DEG C, cold-resistant (5 ± 1) DEG C.Result is as shown in table 1-table 4.
Table 1: the first peripheral stability test result.
Table 2: second week stability test result.
Table 3: the 3rd peripheral stability test result.
Table 4: 4th week stability test result.
From table 1-table 4, tomato leaf extract energy long-term stability prepared by the present invention is deposited.
Two, the human body patch experiment of tomato leaf extract
Organize the human body skin patch Experimental Standardization that 30 volunteers record according to " cosmetics health specification " (2007 editions), the tomato leaf extract of test obtained by the embodiment of the present invention 1, result is as shown in table 5.
Table 5: patch test
| Tested object | Content measurement | Test result | Judge |
| 30 volunteers | Skin enclosed type patch is tested | 30 routine experimenters are negative reaction | Judge the Potential feasibility that tested material has no adverse reaction to human body skin |
Three, the vitamin C of tomato leaf extract and general flavone content test
3.1 test purpose
3.1.1 vitamin C and general flavone content in the tomato leaf extract prepared by the embodiment of the present invention is recorded;
3.1.2 investigate tomato leaf method for preparing extractive and slightly propose the impact on vitamin C in extract and general flavone content of ethanol contend concentration in step solution.
3.2 method of testing
Comparative example 1
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly to extract: preparation mass fraction is the aqueous solution of sodium bisulfite of 0.1%, then to add ethanol to ethanol contend concentration be 20%, obtains solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add 1,3 butylene glycol at dry step 3 obtained, dry and 1, the mass volume ratio of 3-butanediol is 1:5, and-10 DEG C static 2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.
Comparative example 2
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly to extract: preparation mass fraction is the aqueous solution of sodium bisulfite of 0.1%, then to add ethanol to ethanol contend concentration be 60%, obtains solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add 1,3 butylene glycol at dry step 3 obtained, dry and 1, the mass volume ratio of 3-butanediol is 1:5, and-10 DEG C static 2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.
The each 100g of tomato leaf extract obtained by Example 1-3 and comparative example 1-2, mensuration Vitamin C content (see: " in fruit, vegetable, mensuration-uv-spectrophotometric rapid assay methods of Vitamin C content is inquired into " that [spectrographic laboratory] the 23rd volume the 4th is interim) and general flavone content (see: " wild Dendrocalamus giganteus Munro Folium Bambosae flavone content and Antioxidative Activity Determination experiment thereof " that [western forest-science] the 42nd volume the 2nd is interim), test result is as following table 6:
Table 6: working substance content
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 | Comparative example 1 | |
| Total flavones (mg/100g) | 8210.1 | 8105.0 | 8127.5 | 2531.4 | 4230.2 |
| Vitamin c (mg/100g) | 342.1 | 325.4 | 305.2 | 114.7 | 156.2 |
As can be seen from Table 6, in the tomato leaf extract that the present embodiment 1-3 is obtained, vitamin C average content is 324.2mg/100g, and total flavones average content is 8147.5mg/100g, can approximate representation be in this extract, general flavone content >=8Wt%, Vitamin C content >=0.3Wt%.In addition, the Vitamin C content obtained by comparative example 1-2 and general flavone content, all lower than embodiment 1-3, illustrate that in the thick extraction step solution of tomato leaf method for preparing extractive, ethanol contend concentration controls at 30%-50% more excellent.
Four, the antioxidant activity test of tomato leaf extract
4.1 test purpose
4.1.1 the antioxidant activity of tomato leaf extract prepared by the present invention is measured;
4.1.2 the mass percent of tomato leaf method for preparing extractive thick extraction step solution sulfite hydrogen sodium is investigated on the impact of extract antioxidant activity.
4.2 method of testing
Comparative example 3:
A preparation method for tomato leaf extract, comprises following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly to extract: preparation mass fraction is the aqueous solution of sodium bisulfite of 0.05%, then to add ethanol to ethanol contend concentration be 30%, obtains solution.In the tomato leaf crushed material of step one, add this solution, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: add 1,3 butylene glycol at dry step 3 obtained, dry and 1, the mass volume ratio of 3-butanediol is 1:5, and-10 DEG C static 2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract.
Example 1 and each 100g of tomato leaf extract obtained by comparative example 3, antioxidant activity is measured (see Wang Qi, Tian Diying, Yang Ronghua by DPPH method, the comparison of fruit and vegerable Antioxidative Activity Determination method, [food and fermentation industries] 5 phases in 2008), the antioxidant activity recording the tomato leaf extract obtained by embodiment 1 is 95.73%, and the antioxidant activity of the tomato leaf extract obtained by comparative example 3 is 60.21%.Illustrate that the tomato leaf extract obtained by the embodiment of the present invention has good antioxidant activity, also illustrate that the mass percent of tomato leaf method for preparing extractive thick extraction step solution sulfite hydrogen sodium controls at 0.1-0.5% more excellent.
Five, the crease-resistant effect of beauty treatment of the cosmetics of tomato leaf extract is added with.
Tomato leaf extract is applied in the cosmetics of each dosage form, the substrate of these cosmetics be vegetable and animals oils, mineral oil, wax, higher alcohol, fatty alcohol, silicone oil, surfactant, phospholipid, alcohols, polyalcohols, water-soluble polymer, oil-soluble polymers class, mineral or deionization who, the dosage form of cosmetics is water preparation, cream, washing liquid or emulsion.
Below illustrate dosage form of the present invention example.
[dosage form example 1] cosmetic water
Toner/smoothing toner comprises the component of following mass percent: glycerol 5%, propylene glycol 5%, 1,3 butylene glycol 5%, allantoin 1%, hyaluronate sodium 0.05%, tomato leaf extract 5%, cellulose gum 0.01%, antiseptic 0.2%, water surplus.
This cosmetic water can be prepared by following technique: join in agitated kettle by glycerol, propylene glycol, 1,3 butylene glycol, allantoin, hyaluronate sodium, cellulose gum, water, be heated to 85 DEG C; Stirring is cooled to 30-40 DEG C and adds antiseptic, tomato leaf extract.
[dosage form example 2] essence cream
Essence cream comprises the component of following mass percent: cetearyl alcohol 2%, caprylic/capric triglyceride 5%, squalane 3%, polydimethylsiloxane 2%, ring five polydimethylsiloxane 5%, glycerol 5%, 1,3 butylene glycol 3%, allantoin 0.2%, tomato leaf extract 5%, HANSHENGJIAO 0.3%, polyacrylamide and C13-14 isoparaffin and cinnamic alcohol ether-70.8%, antiseptic 0.3%, water surplus.
This essence cream can be prepared by following technique: cetearyl alcohol, caprylic/capric triglyceride, squalane, polydimethylsiloxane, ring five polydimethylsiloxane are added in oil phase pot as A, are heated to 80 DEG C; Glycerol, 1,3 butylene glycol, allantoin, HANSHENGJIAO, water are added in emulsifying pot as B, are heated to 80 DEG C; A is added to B phase homogenizing 2-3 minute; Add polyacrylamide and C13-14 isoparaffin and cinnamic alcohol ether-7 homogenizing 2-3 minute; Stirring is cooled to 30-40 DEG C and adds tomato leaf extract, antiseptic.
The evaluation of atraumatic human body is carried out to the essence cream prepared by dosage form example 2, as a control group with a commercially available cream frost laying claim to the crease-resistant effect of good beauty treatment simultaneously.
Tested object: each experimental group is 20 women (35-50 year); Test zone: crows feet area; Use: twice daily, continue use 4 weeks; Test event: the soft degree of skin, wrinkle depth (crows feet area).Result on trial refers to table 7.
Table 7: atraumatic human body evaluation test result
As can be seen from Table 7, the essence cream prepared by the present invention shows good beauty treatment anti-wrinkle effect compared with matched group commercially available prod.
Evaluated by above physicochemical property detection, human body patch test and atraumatic human body, prove that tomato leaf extract is a kind of steady quality, index and definite ingredients, there is the vegetable raw material of crease-resistant effect of improving looks, safe and non-stimulating, independent or other function raw material composite can be used in the cosmetics of any dosage form as function raw material.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (5)
1. a preparation method for tomato leaf extract, comprises the following steps:
Step one, pulverizing: the tomato leaf of drying is crushed to 100 orders;
Step 2, slightly extraction: the aqueous solution of preparation containing sodium sulfite, then add ethanol, obtain solution, this solution is added in the tomato leaf crushed material of step one, crushed material and solution quality, than being 1:10 ~ 1:20, extracting 4-6 hour, repeat extraction three times at 60-90 DEG C of temperature;
Step 3, filtration drying: the crude extract of step 2 is cooled to 20-30 DEG C, with 1000-2000 order filter cloth filtering insoluble matter, be evaporated to 1/5 to 1/10 of extracting liquid volume in step 2, then carry out vacuum drying and obtain dry;
Step 4, dissolving are refined: again the dry that step 3 obtains is added solvent, the mass volume ratio of dry and solvent is 1:5, stand at low temperature 1-2 days, in centrifuges with the centrifugal 30min of rotating speed 5000rpm, collect supernatant, obtain refining tomato leaf extract;
It is characterized in that, the described ethanol contend concentration slightly carried in the solution that step obtains is 30-50%, and described dissolving purification step stand at low temperature temperature is-10 DEG C ~ 0 DEG C, and described sodium sulfite mass fraction is in aqueous 0.1-0.5%.
2. the preparation method of tomato leaf extract according to claim 1, is characterized in that, the solvent added in described dissolving purification step is 1,3 butylene glycol.
3. the tomato leaf extract according to claim 1 or 2 obtained by preparation method.
4. tomato leaf extract according to claim 3 is preparing the application in cosmetics.
5. tomato leaf extract according to claim 4 is preparing the application in cosmetics, described toiletry bag is containing substrate and tomato leaf extract, it is characterized in that: in the middle of described tomato leaf extract, general flavone content >=8Wt%, Vitamin C content >=0.3Wt%; Described substrate is vegetable and animals oils, mineral oil, silicone oil, phospholipid, alcohols or deionized water; The dosage form of described cosmetics is water preparation, cream, washing liquid or emulsion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410031744.XA CN103751061B (en) | 2014-01-23 | 2014-01-23 | Tomato leaf extract and the application in cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410031744.XA CN103751061B (en) | 2014-01-23 | 2014-01-23 | Tomato leaf extract and the application in cosmetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103751061A CN103751061A (en) | 2014-04-30 |
| CN103751061B true CN103751061B (en) | 2016-01-20 |
Family
ID=50518500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410031744.XA Active CN103751061B (en) | 2014-01-23 | 2014-01-23 | Tomato leaf extract and the application in cosmetics |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103751061B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625700A (en) * | 2017-10-18 | 2018-01-26 | 佛山市飞时达新材料科技有限公司 | A kind of skin whitening, moisturizing cosmetics and preparation method thereof |
| CN107693424A (en) * | 2017-10-31 | 2018-02-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of whitening anti-aging skin care item and preparation method thereof |
| CN111084795A (en) * | 2019-09-12 | 2020-05-01 | 天津芸熙生物技术有限公司 | Preparation process of compound preparation extracted from sandalwood leaves at low temperature |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430968A (en) * | 2003-01-30 | 2003-07-23 | 复旦大学 | Injection liquid of extractive gingko leaves and its preparing method |
| CN1919219A (en) * | 2005-08-26 | 2007-02-28 | 蔡南桂 | Refining method of ginko total chromocor and method for preparing ginko damo injection |
| CN102224831A (en) * | 2011-04-28 | 2011-10-26 | 上海交通大学 | Control method of tetranychus cinnabarinus based on tomato extracts |
-
2014
- 2014-01-23 CN CN201410031744.XA patent/CN103751061B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430968A (en) * | 2003-01-30 | 2003-07-23 | 复旦大学 | Injection liquid of extractive gingko leaves and its preparing method |
| CN1919219A (en) * | 2005-08-26 | 2007-02-28 | 蔡南桂 | Refining method of ginko total chromocor and method for preparing ginko damo injection |
| CN102224831A (en) * | 2011-04-28 | 2011-10-26 | 上海交通大学 | Control method of tetranychus cinnabarinus based on tomato extracts |
Non-Patent Citations (2)
| Title |
|---|
| 《西红柿叶中茄尼醇的提取及测定》;吴锦明等;《理化检验—化学分册》;20101231;第46卷;第698-699页 * |
| 番茄叶中总黄酮提取工艺及含量测定的研究;杜成智等;《湖北农业科学》;20140120;第53卷(第2期);第392-394页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103751061A (en) | 2014-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5269160B2 (en) | Bioactive liquid composition and method for producing the same | |
| CN106389175B (en) | A kind of nourishing and moisturizing lotion containing Rosa Damascana | |
| CN102670436A (en) | Skin-whitening anti-aging cosmetic containing Cistanche tubulosa extract and its preparation method | |
| CN103976909B (en) | A kind of Herba Leibnitziae extracting solution and its preparation method and application | |
| CN103251532A (en) | Tea flower skin cream containing tea flower | |
| CN105147550A (en) | Whitening and moisture-preserving mask liquid containing common nostoc extract and preparation method thereof | |
| CN102113987A (en) | Cosmetic containing natural plant extractives and preparation method thereof | |
| CN103751061B (en) | Tomato leaf extract and the application in cosmetics | |
| CN105250180A (en) | Rose fresh water and preparation method and application thereof | |
| CN102240254A (en) | Snow lotus herb extract and preparation method and application thereof | |
| CN107468568A (en) | A kind of persimmon leaf polyphenol with whitening sun protection activity and its preparation method and application | |
| Huang et al. | Simultaneous recovery of glycyrrhizic acid and liquiritin from Chinese licorice root (Glycyrrhiza uralensis Fisch) by aqueous two-phase system and evaluation biological activities of extracts | |
| US20150182443A1 (en) | Traditional chinese medicine extract composition with whitening skin-care function adn its preparation method | |
| CN107737061A (en) | A kind of cosmetic composition and preparation method thereof | |
| CN102630943A (en) | Spirulina gamma-linolenic acid extractive and preparation method thereof | |
| KR101676292B1 (en) | Cosmetic composition comprising an mixed extract of tangle, okra and yam and manufacturing method thereof | |
| CN101843311A (en) | Method for preparing hippophae rhamnoides seed micro powder capsules | |
| CN107375025A (en) | A kind of anti-acne toner and preparation method thereof | |
| Jeong et al. | Cosmetic effect of mixed plant extracts including Saururus Chinensis, Morus Bombycis stem and Morus Papyrifera stem | |
| CN102178629B (en) | Silybum marianum essential oil skin-care cream and preparation method thereof | |
| CN110179698A (en) | A kind of skin whitening, moisturizing frost and preparation method thereof of the extract of Ke containing multiple-ear rock | |
| CN105616217B (en) | A kind of preparation method of plant moisturizing skin care item | |
| JP4748962B2 (en) | Moisturizer, cell activator, whitening agent, and antioxidant | |
| CN106860120A (en) | A kind of anti-apolexis composition, its preparation method and application | |
| CN102311510A (en) | Method for extracting perillafrutescens L. polysaccharide from perillafrutescens L. seeds and purifying perillafrutescens L. polysaccharide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20151029 Address after: Two road 510545 in Guangdong Province, Baiyun District of Guangzhou City Land Development Zone Park No. 3 Applicant after: Guangzhou Qian Baidu cosmetics company limited Address before: 510370 Guangdong province Guangzhou City Creek Road in Panlong industrial zone of Liwan District dragon two friends of a 6 storey industrial building Applicant before: Guangzhou Danqi Daily Chemical Factory Co., Ltd. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: He Shiwen Inventor before: Cai Yiwen Inventor before: Yang Guangqun |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170405 Address after: 510440 Guangzhou, Baiyun District, Guangdong Luo Gang Village Xinxing Industrial Zone, No. 1 Patentee after: Guangzhou Hesheng Cosmetics Co., Ltd. Address before: Two road 510545 in Guangdong Province, Baiyun District of Guangzhou City Land Development Zone Park No. 3 Patentee before: Guangzhou Qian Baidu cosmetics company limited |