CN107693424A - A kind of whitening anti-aging skin care item and preparation method thereof - Google Patents

A kind of whitening anti-aging skin care item and preparation method thereof Download PDF

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Publication number
CN107693424A
CN107693424A CN201711056177.3A CN201711056177A CN107693424A CN 107693424 A CN107693424 A CN 107693424A CN 201711056177 A CN201711056177 A CN 201711056177A CN 107693424 A CN107693424 A CN 107693424A
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parts
extract
skin care
care item
skin
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陈海佳
葛啸虎
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
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  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of whitening anti-aging skin care item, the raw material of following parts by weight is included:5~30 parts of 15~45 parts of Jasminum sambac Air leaf cell extract, 3~25 parts of tomato leaf extract, 5~20 parts of grape seed extract, 10~25 parts of Honegsukle flower P.E and honeysuckle flower extract.Meanwhile the invention discloses the preparation method of the whitening anti-aging skin care item.Whitening anti-aging skin care item provided by the invention are made up of active skull cap components, safe and non-stimulating, can effectively remove free radical, improve skin aging state, desalinate microgroove, lift elasticity of skin.Skin cell melanin content is reduced simultaneously, makes skin whitening bright, there is good whitening anti-aging effect.

Description

A kind of whitening anti-aging skin care item and preparation method thereof
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of whitening anti-aging skin care item and preparation method thereof.
Background technology
Delay skin aging is exactly the pursuit that numerous women dream of since ancient times, and the mankind have ratio for aging at present More visible research, at present in the theory of aging, free radical theory obtains more accreditation, with itself age growth and The influence of external environment, people's interior free yl increases, and the ability for removing free radical can also decline, superfluous free radical meeting Cause body injury, bring many skin problems, such as wrinkle, spot etc. therewith.
Current domestic skin whitening, moisturizing, nti-freckle, anti-aging class product have turned into one of main product in skin care item.Manyization Cosmetics are learned to contain as mercurous, hydroquinones preparation, potential safety hazard are high.It is now wide variety of to have vitamin C, kojic acid and its spread out Biology etc., but property is unstable, meets light, hot destructible.Therefore, Chinese medicinal skin care product increasingly receives the favor of consumer.In The extract obtained after medicine is extracted uses as skin-care product additive, can be efficiently against above mentioned problem.But Chinese medicine is former The selection of material and compatibility relationship are of crucial importance to the effect of skin care item, and selection or the bad not only influence of compatibility are understood effect and may gone back Other side effects can be brought.
The content of the invention
Based on this, a kind of whitening anti-aging is provided it is an object of the invention to overcome above-mentioned the deficiencies in the prior art part Skin care item, it is made up of active skull cap components, and safety stimulates, and can effectively remove free radical, improves skin aging state, and desalination is thin Line, elasticity of skin is lifted, while there is the effect of Whitening, spot.
To achieve the above object, the technical scheme taken of the present invention is:A kind of whitening anti-aging skin care item, comprising following heavy Measure the raw material of part:15~45 parts of Jasminum sambac Air leaf cell extract, 3~25 parts of tomato leaf extract, grape seed extract 5~ 20 parts, 5~30 parts of 10~25 parts of Honegsukle flower P.E and honeysuckle flower extract.
Preferably, the whitening anti-aging skin care item include the raw material of following parts by weight:Jasminum sambac Air leaf cell extracts 20~40 parts of thing, 5~20 parts of tomato leaf extract, 8~16 parts of grape seed extract, 13~20 parts of Honegsukle flower P.E and honeysuckle 3~18 parts of flower extract.
Preferably, the whitening anti-aging skin care item include the raw material of following parts by weight:Jasminum sambac Air leaf cell extracts 7 parts of 25 parts of thing, 8 parts of tomato leaf extract, 12 parts of grape seed extract, 15 parts of Honegsukle flower P.E and honeysuckle flower extract.
Preferably, the whitening anti-aging skin care item include the raw material of following parts by weight:Jasminum sambac Air leaf cell extracts 10 parts of 30 parts of thing, 12 parts of tomato leaf extract, 10 parts of grape seed extract, 18 parts of Honegsukle flower P.E and honeysuckle flower extract.
Preferably, the whitening anti-aging skin care item include the raw material of following parts by weight:Jasminum sambac Air leaf cell extracts 15 parts of 35 parts of thing, 10 parts of tomato leaf extract, 15 parts of grape seed extract, 14 parts of Honegsukle flower P.E and honeysuckle flower extract.
It is another object of the present invention to provide the preparation method of the whitening anti-aging skin care item.
To achieve the above object, the technical scheme taken of the present invention is:A kind of preparation method of whitening anti-aging skin care item, Comprise the following steps:
(1) Jasminum sambac Air leaf cell extract, tomato leaf extract and Honegsukle flower P.E are weighed in proportion, add 65 ~85 DEG C of water, side add waterside and are slowly stirred uniformly, and 30min is incubated with after 70 DEG C;
(2) grape seed extract and honeysuckle flower extract are weighed in proportion, adds 50~65 DEG C of water, and side adds waterside and delayed Slowly stir, 30min is incubated with after 60 DEG C;
(3) mixture in step (2) is slowly added in the mixture of step (1), after stirring, is cooled to 37 DEG C Hereinafter, dispense and produce.
Preferably, 80 DEG C of water is added in the step (1);60 DEG C of water is added in step (2).
Preferably, the preparation method of the Jasminum sambac Air leaf cell extract comprises the following steps:By Jasminum sambac Air Leaf crushes, and the mass fraction for adding 13 times of coarse powder weight is 80% ethanol, vacuum is placed in as in the environment of 0.5MPa, in 65 DEG C ultrasonic extraction 20min, ultrasonic power 400W.
Preferably, the tomato leaf extract is tomato leaf alcohol extracting thing, is prepared by following methods:By tomato leaf powder Be broken to can cross 80 mesh sieves, add its 15 times of volume of weight mass fraction be 75% ethanol, heating and refluxing extraction 3 times, every time 2h, merges extract solution, filtering, and filtrate decompression is removed ethanol, is drying to obtain.
Preferably, the grape seed extract is grape pip alcohol extracting thing, is prepared by following methods:Grape pip is broken Powder, the mass fraction for adding its 10 times of volume of weight is 80% ethanol, heating and refluxing extraction 2 times, each 1h, merges extraction Liquid, filtering, filtrate decompression are removed ethanol, are drying to obtain.
Preferably, the Honegsukle flower P.E is honeysuckle alcohol extracting thing, is prepared by following steps:By honeysuckle powder Broken, the mass fraction for adding coarse powder 10 times of volumes of weight is 80% ethanol, heating and refluxing extraction 3 times, each 1h, merges extraction Liquid, concentration remove ethanol, are drying to obtain.
Preferably, the honeysuckle flower extract is honeysuckle flowers alcohol extracting thing, is prepared by following methods:By honeysuckle pollen The broken mesh sieve of mistake 60, by solid-liquid ratio 1:12 addition mass fractions are 80% ethanol, and water-bath refluxing extraction 3 is carried out under the conditions of 85 DEG C It is secondary, each 2h, filter while hot, merging filtrate, concentration removes ethanol, is drying to obtain.
Present inventor has found by substantial amounts of research, by Jasminum sambac Air leaf cell extract, tomato leaf extract, Grape seed extract, Honegsukle flower P.E and honeysuckle flower extract prepare skin care item as raw material compounding, have between each raw material Good cooperative effect, there is significant whitening anti-aging effect.The compatibility amount of raw material is that inventor unites by substantial amounts of research Meter analysis is got, and each raw material can play good synergy in the amount ranges, not have any side-effects simultaneously.
Relative to prior art, beneficial effects of the present invention are:Whitening anti-aging skin care item of the present invention by natural activity into It is grouped into, safety stimulates, and can effectively remove free radical, improves skin aging state, desalinates microgroove, lifts elasticity of skin.Simultaneously Skin cell melanin content is reduced, makes skin whitening bright, there is good whitening anti-aging effect.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.
Embodiment 1
A kind of embodiment of whitening anti-aging skin care item of the present invention, include the raw material of following parts by weight:Jasminum sambac Air leaf 15 parts of cell extract, 3 parts of tomato leaf extract, 5 parts of grape seed extract, 10 parts of Honegsukle flower P.E and honeysuckle flower extract 5 parts.
Embodiment 2
A kind of embodiment of whitening anti-aging skin care item of the present invention, include the raw material of following parts by weight:Jasminum sambac Air leaf 45 parts of cell extract, 25 parts of tomato leaf extract, 20 parts of grape seed extract, 25 parts of Honegsukle flower P.E and honeysuckle flowers are extracted 30 parts of thing.
Embodiment 3
A kind of embodiment of whitening anti-aging skin care item of the present invention, include the raw material of following parts by weight:Jasminum sambac Air leaf 25 parts of cell extract, 8 parts of tomato leaf extract, 12 parts of grape seed extract, 15 parts of Honegsukle flower P.E and honeysuckle flowers are extracted 7 parts of thing.
Embodiment 4
A kind of embodiment of whitening anti-aging skin care item of the present invention, include the raw material of following parts by weight:Jasminum sambac Air leaf 30 parts of cell extract, 12 parts of tomato leaf extract, 10 parts of grape seed extract, 18 parts of Honegsukle flower P.E and honeysuckle flowers are extracted 10 parts of thing.
Embodiment 5
A kind of embodiment of whitening anti-aging skin care item of the present invention, include the raw material of following parts by weight:Jasminum sambac Air leaf 35 parts of cell extract, 10 parts of tomato leaf extract, 15 parts of grape seed extract, 14 parts of Honegsukle flower P.E and honeysuckle flowers are extracted 15 parts of thing.
Embodiment 6
A kind of embodiment of whitening anti-aging skin care item preparation method of the present invention, comprises the following steps:
(1) Jasminum sambac Air leaf cell extract, tomato leaf extract and Honegsukle flower P.E are weighed in proportion, add 65 DEG C water, side add waterside be slowly stirred uniformly, with after 70 DEG C insulation 30min;(2) weigh in proportion grape seed extract and Honeysuckle flower extract, 50 DEG C of water is added, side adds waterside and is slowly stirred uniformly, and 30min is incubated with after 60 DEG C;(3) will step Suddenly the mixture in (2) is slowly added in the mixture of step (1), after stirring, is cooled to less than 37 DEG C, is dispensed and produce.
The preparation method of the Jasminum sambac Air leaf cell extract comprises the following steps:Jasminum sambac Air leaf is crushed, The mass fraction for adding 13 times of coarse powder weight is 80% ethanol, vacuum is placed in as in the environment of 0.5MPa, in 65 DEG C of ultrasounds Extract 20min, ultrasonic power 400W.
The tomato leaf extract is tomato leaf alcohol extracting thing, is prepared by following methods:Tomato leaf is crushed to energy 80 mesh sieves are crossed, the mass fraction for adding its 15 times of volume of weight is 75% ethanol, heating and refluxing extraction 3 times, each 2h, is merged Extract solution, filtering, filtrate decompression are removed ethanol, are drying to obtain.
The grape seed extract is grape pip alcohol extracting thing, is prepared by following methods:By grape pip flour, add The mass fraction of its 10 times of volume of weight is 80% ethanol, heating and refluxing extraction 2 times, each 1h, merges extract solution, is filtered, Filtrate decompression removes ethanol, is drying to obtain.
The Honegsukle flower P.E is honeysuckle alcohol extracting thing, is prepared by following steps:Honeysuckle is crushed, added The mass fraction of 10 times of volumes of coarse powder weight is 80% ethanol, heating and refluxing extraction 3 times, each 1h, merges extract solution, concentration Ethanol is removed, is drying to obtain.
The honeysuckle flower extract is honeysuckle flowers alcohol extracting thing, is prepared by following methods:Honeysuckle flowers crushed 60 Mesh sieve, by solid-liquid ratio 1:12 addition mass fractions are 80% ethanol, water-bath refluxing extraction are carried out under the conditions of 85 DEG C 3 times, every time 2h, filter while hot, merging filtrate, concentration removes ethanol, is drying to obtain.
Embodiment 7
A kind of embodiment of whitening anti-aging skin care item preparation method of the present invention, comprises the following steps:
(1) Jasminum sambac Air leaf cell extract, tomato leaf extract and Honegsukle flower P.E are weighed in proportion, add 85 DEG C water, side add waterside be slowly stirred uniformly, with after 70 DEG C insulation 30min;(2) weigh in proportion grape seed extract and Honeysuckle flower extract, 65 DEG C of water is added, side adds waterside and is slowly stirred uniformly, and 30min is incubated with after 60 DEG C;(3) will step Suddenly the mixture in (2) is slowly added in the mixture of step (1), after stirring, is cooled to less than 37 DEG C, is dispensed and produce.
The Jasminum sambac Air leaf cell extract, tomato leaf extract, grape seed extract, Honegsukle flower P.E and bear Coltsfoot method for preparing extractive is the same as embodiment 6.
Embodiment 8
A kind of embodiment of whitening anti-aging skin care item preparation method of the present invention, comprises the following steps:
(1) Jasminum sambac Air leaf cell extract, tomato leaf extract and Honegsukle flower P.E are weighed in proportion, add 80 DEG C water, side add waterside be slowly stirred uniformly, with after 70 DEG C insulation 30min;(2) weigh in proportion grape seed extract and Honeysuckle flower extract, 60 DEG C of water is added, side adds waterside and is slowly stirred uniformly, and 30min is incubated with after 60 DEG C;(3) will step Suddenly the mixture in (2) is slowly added in the mixture of step (1), after stirring, is cooled to less than 37 DEG C, is dispensed and produce.
The Jasminum sambac Air leaf cell extract, tomato leaf extract, grape seed extract, Honegsukle flower P.E and bear Coltsfoot method for preparing extractive is the same as embodiment 6.
Embodiment 9
The present embodiment is tested the effect of skin care item in embodiment 1~5.
(1) method of testing
200 healthy women subjects are chosen, the age is between 30~55 years old.All subjects are randomly divided into 5 Test group, respectively using the skin care item in embodiment 1~5.Appropriate skin care item are taken after subject's morning and evening face cleaning of all test groups Face is applied to, and softly massages 2~3min, promotes to absorb.Trial employment period prevents solar exposure, and prohibits the use of other skin cares Product.After continuous use one month, all subjects are carried out with detection and the record of using effect.
(2) effect assessment standard
1st, the whitening effect of skin care item of the present invention is evaluated using the rate of change of dermal melanin content and brightness, specifically Method is as follows:
(1) dermal melanin content:Use Japanese Minolta CD-2600 spectrophotometric analysis subject's face skin Melanin content situation of change.It uses Lab color systems, collects the reflected light vertical with skin surface, in its measurement parameter B reflection from Huang to indigo plant color variation range (value changes scope:+ 60 yellow~-60 are blue), be in the black pigment of skin content Positive correlation, this is relevant with melanin reflection gold-tinted.Before on-test, first the melanin content of each subject's skin is entered Row detection, and record;After testing 3 weeks, the melanin of each subject's skin is detected again, and records.Utilize with Lower formula calculates the melanin rate of descent of skin:Numerical value before melanin rate of descent=(numerical value after numerical value-experiment before experiment)/experiment × 100%.Melanin content rate of descent is bigger, shows that whitening effect is better.
(2) skin brightness:Using the brightness of skin measurement system (VISIA) measurement skin, skin is more bright, is worth It is higher, and skin is more dim, is worth lower.Before on-test, first the brightness of each subject's skin is detected, And record;After experiment one month, the brightness of each subject's skin is detected again, and records.Utilize following public affairs Formula calculates the rate of change of the brightness of skin:Numerical value before brightness rate of change=(numerical value before numerical value-experiment after experiment)/experiment × 100%.Brightness climbing is bigger, shows that whitening effect is better.
2nd, the anti-aging effects of skin care item of the present invention, specific method are evaluated using dermatoglyph degree and the rate of change of elasticity It is as follows:
(1) dermatoglyph degree:Determined using German skin image analysis system (Skin Visiometer SV600) tested The texture situation of person's face skin.Before on-test, first the texture of the skin of each subject is detected, and Record;After experiment one month, the texture of the skin of each subject is detected again, and records.Utilize following public affairs Formula calculates the texture rate of descent of skin:Numerical value before texture rate of descent=(numerical value after numerical value-experiment before experiment)/experiment × 100%.Texture rate of descent is bigger, shows that anti-aging effects are better.
(2) skin elasticity:Subject's face flesh is determined using skin elasticity tester (Cutometer dual MPA580) The elastic numerical value change situation of skin is to evaluate the elastic stage of skin, and numerical value is higher, and surface elasticity of skin is better.On-test it Before, first the elasticity of each subject's skin is detected, and records;After experiment one month, again to each subject The elasticity of skin is detected, and is recorded.The elastic climbing of skin is calculated using below equation:Elastic climbing=(examination Test numerical value before rear numerical value-experiment) numerical value × 100% before/experiment.Elastic climbing is bigger, shows that anti-aging effects are better.
3rd, the evaluation criterion of security of the present invention is as shown in table 1:
The evaluation criterion of 1 security of the present invention of table
(3) test result
After one month, the using effect of all subjects is counted, as a result as shown in table 2.
The skin care item measure of merit result of the present invention of table 2
As shown in Table 2, skin care item are respectively provided with extraordinary whitening and resisted in the embodiment of the present invention 1~5 (test group 1~5) Aging effects, average black cellulose content rate of descent is up to more than 30%, and average texture degree rate of descent is up to more than 35%.Subject reacts After skin care item of the present invention, skin wrinkle significantly reduces, and becomes to compact flexible, pale glossy.And all subjects Do not occur phenomena such as allergy, general red, itch or long acne in use, it is safe and non-stimulating.Wherein, (the test group of embodiment 5 5) the skin care item whitening and anti-aging effect in is best.
Embodiment 10
Skin care item of the present invention include Jasminum sambac Air leaf cell extract, tomato leaf extract, grape seed extract, gold and silver Flower extract and honeysuckle flower extract.To study influence of the selection of raw material of skin care articles to whitening and anti-aging effect, this implementation Raw material selection of the example to skin care item is tested.
(1) experimental design
To inquire into influence of the selection of raw material to skin care item effect of the present invention, contrived experiment group 1~6, specifically such as the institute of table 3 Show.The dosage of each raw material is the same as embodiment 5, the same implementation of preparation method of each raw material extracting method and skin care item in experimental group 1~6 Example 8.
The experimental group of table 3 designs
(2) experimental method
1st, skin care item whitening effect is tested:TYR inhibition of enzyme activity is tested
Tyrosinase is rate-limiting enzyme main in melanin forming process, and the active size of the enzyme decides that melanin is formed Quantity, its activity it is higher, then product melanin generation it is more.Therefore, it is effective reduction melanin to suppress tyrosinase activity A kind of approach of generation.Catalytic reaction can occur for TYR enzyme and its substrate TYR, when being added in reaction system After having the reagent that TYR inhibition of enzyme activity acts on, inhibitory action can be produced to catalytic reaction, L- is added with by measure Before and after the reagent of tyrosinase activity inhibitory action at 475nm absorbance change, have TYR enzymatic activity to evaluate this The reagent of inhibitory action is to the inhibiting rate of TYR enzymatic activity, and inhibiting rate is higher, and whitening effect is better.
Test method is:PBS, sample solution to be tested and tyrosine solution are added into test tube successively, in 35 DEG C of water-baths 10min, TYR enzyme liquid is then added, mix, 30min is incubated at 35 DEG C, the rapid reaction solution that determines is at 475mm Light absorption value.It is experiment that control group, which is added with the isometric distilled water of testing sample solution, the sample solution to be tested, in experiment The skin care item that group 1~6 is prepared, addition volume is 0.5mL.Inhibiting rate is calculated by below equation:Inhibiting rate=(control Group light absorption value-sample sets light absorption value)/control group light absorption value × 100%.
2nd, skin care item anti-aging effects are tested:Remove the experiment of DPPH free radicals
DPPH is a kind of very stable free radical, if composition can be removed, then it represents that composition has reduction hydroxyl certainly By the effect of base or oxyradical.DPPH has a characteristic absorption peak at 517nm, when running into free radical scavenger, DPPH diminishes in the absorbance of maximum absorption wave strong point.Therefore, composition pair can be evaluated by determining the change of absorbance DPPH elimination effect, so as to evaluate its anti-aging effects.
Test method is:The skin care item and 2mL 20mmol/L DPPH solution in 2mL experimental groups 1~6 are taken respectively, are mixed After react 30min, determine absorbance of each experimental group reaction solution at 517nm wavelength rapidly, control solvent is with absolute ethyl alcohol generation Replace.Clearance rate is calculated as follows:Clearance rate=[1- (A1-A2)/A3] × 100.Wherein, A1 is that 2mL DPPH solution and 2mL are real Test the absorbance of the reaction solution of group 1~6 skin care item composition;A2 is the skin care item of 2mL experimental groups 1~6 and 2mL absolute ethyl alcohols composition The absorbance of reaction solution;A3 is the absorbance of 2mL DPPH solution and the reaction solution of 2mL absolute ethyl alcohols composition.
(3) experimental result
After experiment terminates, the effect for the skin care item that each experimental group different material is prepared is evaluated, as a result such as table 4 It is shown:
The experimental result of table 4
From above-mentioned experimental result, it is anti-ageing that 5 kinds of raw materials of skin care item of the present invention can obtain best whitening when using simultaneously Old effect (experimental group 1).The composition of skin care item of the present invention is that inventor obtains by numerous studies, can be produced very between each component Good synergy.Lack any raw material, its effect can be all remarkably decreased (experimental group 2~6).Other lack two kinds or three The experimental result of kind raw material is similar with the present embodiment, and specific data are omitted.
Embodiment 11
Whitening anti-aging skin care item of the present invention, include the raw material of following parts by weight:Skin care item of the present invention are planted comprising Jasmine 15~40 parts of thing leaf cell extract, 5~20 parts of tomato leaf extract, 5~20 parts of grape seed extract, Honegsukle flower P.E 5 ~20 parts and 5~20 parts of honeysuckle flower extract.To study influence of the raw material of skin care articles compatibility amount of the present invention to effect, the present embodiment The usage amount of each raw material of skin care item is studied.
(1) experimental design
The present embodiment carries by taking the usage amount of Jasminum sambac Air leaf cell extract as an example to inquire into Jasminum sambac Air leaf cell Take influence of the usage amount of thing to skin care item whitening anti-aging effect of the present invention, contrived experiment group 7~11, it is specific as shown in table 5. The dosage of each other raw materials of experimental group is with embodiment 5, and the preparation method of each raw material extracting method and skin care item is the same as embodiment 8.
The experimental group of table 5 designs
Experimental group Jasminum sambac Air leaf cell extract usage amount/parts by weight
Experimental group 7 15 parts
Experimental group 8 40 parts
Experimental group 9 32 parts
Experimental group 10 14 parts
Experimental group 11 41 parts
(2) experimental method
The present embodiment experimental method is the same as embodiment 10.
(3) experimental result
After experiment terminates, the effect for the skin care item that each experimental group raw material is prepared is evaluated, and evaluation criterion is the same as real Example 10 is applied, as a result as shown in table 6:
The experimental result of table 6
From above-mentioned experimental result, the usage amount of skin care item Jasminum sambac Air leaf cell extract of the present invention is 15~40 Good whitening and anti-aging effect can be obtained between parts by weight when (experimental group 7~9), usage amount not in this range The using effect of skin care item can be significantly affected by increasing or decreasing (experimental group 10~11).The use of each raw material of skin care item of the present invention Amount is that inventor passes through the best proportion that counts of many experiments, and the usage amount of each raw material can be with the range of parts by weight of the present invention Ensure that skin care item obtain good using effect, any one raw material usage amount increases or decreases the association that can all influence between raw material Same effect, the effect of so as to influence skin care item.Tomato leaf extract, grape seed extract, Honegsukle flower P.E and honeysuckle flowers carry Take the experimental result of thing usage amount similar with the present embodiment, specific data are omitted.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention And scope.

Claims (9)

1. a kind of whitening anti-aging skin care item, it is characterised in that include the raw material of following parts by weight:Jasminum sambac Air leaf cell carries Take 15~45 parts of thing, 3~25 parts of tomato leaf extract, 5~20 parts of grape seed extract and is born 10~25 parts of Honegsukle flower P.E 5~30 parts of coltsfoot extract.
2. whitening anti-aging skin care item according to claim 1, it is characterised in that include the raw material of following parts by weight:Jasmine 20~40 parts of jasmine flowering plant leaf cell extract, 5~20 parts of tomato leaf extract, 8~16 parts of grape seed extract, honeysuckle carries Take 3~18 parts of 13~20 parts of thing and honeysuckle flower extract.
3. whitening anti-aging skin care item according to claim 1, it is characterised in that include the raw material of following parts by weight:Jasmine 35 parts of jasmine flowering plant leaf cell extract, 10 parts of tomato leaf extract, 15 parts of grape seed extract, 14 parts of Honegsukle flower P.E and 15 parts of honeysuckle flower extract.
4. whitening anti-aging skin care item according to claim 1, it is characterised in that include the raw material of following parts by weight:Jasmine 30 parts of jasmine flowering plant leaf cell extract, 12 parts of tomato leaf extract, 10 parts of grape seed extract, 18 parts of Honegsukle flower P.E and 10 parts of honeysuckle flower extract.
5. whitening anti-aging skin care item according to claim 1, it is characterised in that include the raw material of following parts by weight:Jasmine 25 parts of jasmine flowering plant leaf cell extract, 8 parts of tomato leaf extract, 12 parts of grape seed extract, 15 parts of Honegsukle flower P.E and 7 parts of honeysuckle flower extract.
6. according to the preparation method of any one of Claims 1 to 5 whitening anti-aging skin care item, it is characterised in that including with Lower step:
(1) Jasminum sambac Air leaf cell extract, tomato leaf extract and Honegsukle flower P.E are weighed in proportion, add 65~85 DEG C water, side add waterside be slowly stirred uniformly, with after 70 DEG C insulation 30min;
(2) grape seed extract and honeysuckle flower extract are weighed in proportion, adds 50~65 DEG C of water, and side adds waterside and slowly stirred Mix uniformly, 30min is incubated with after 60 DEG C;
(3) mixture in step (2) is slowly added in the mixture of step (1), after stirring, be cooled to 37 DEG C with Under, dispense and produce.
7. preparation method according to claim 6, it is characterised in that 80 DEG C of water is added in the step (1);Step (2) 60 DEG C of water is added in.
8. preparation method according to claim 6, it is characterised in that the preparation of the Jasminum sambac Air leaf cell extract Method comprises the following steps:Jasminum sambac Air leaf is crushed, the mass fraction for adding 13 times of coarse powder weight is 80% ethanol, is put In the environment of vacuum is 0.5MPa, in 65 DEG C of ultrasonic extraction 20min, ultrasonic power 400W.
9. preparation method according to claim 6, it is characterised in that the tomato leaf extract is tomato leaf alcohol extracting Thing;The grape seed extract is grape pip alcohol extracting thing;The Honegsukle flower P.E is honeysuckle alcohol extracting thing;The honeysuckle Flower extract is honeysuckle flowers alcohol extracting thing.
CN201711056177.3A 2017-10-31 2017-10-31 A kind of whitening anti-aging skin care item and preparation method thereof Withdrawn CN107693424A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110478290A (en) * 2019-08-19 2019-11-22 爱思开百朗德生物科技(海门)有限公司 A kind of cosmetic composition and preparation method thereof with moisturizing senile-resistant efficacy
CN117883340A (en) * 2024-01-09 2024-04-16 广州市脊柱医学研究中心 A method for preparing composition containing multiple natural plant components and skin care product thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103751061A (en) * 2014-01-23 2014-04-30 广州丹奇日用化工厂有限公司 Tomato leaf extract and application thereof in cosmetics
CN104622758A (en) * 2015-02-11 2015-05-20 广州赛莱拉干细胞科技股份有限公司 Preparation method and application of jasmine plant leaf cell extract
CN106852830A (en) * 2016-12-03 2017-06-16 长沙协浩吉生物工程有限公司 A kind of compound method of cleawhite over-night essences

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103751061A (en) * 2014-01-23 2014-04-30 广州丹奇日用化工厂有限公司 Tomato leaf extract and application thereof in cosmetics
CN104622758A (en) * 2015-02-11 2015-05-20 广州赛莱拉干细胞科技股份有限公司 Preparation method and application of jasmine plant leaf cell extract
CN106852830A (en) * 2016-12-03 2017-06-16 长沙协浩吉生物工程有限公司 A kind of compound method of cleawhite over-night essences

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110478290A (en) * 2019-08-19 2019-11-22 爱思开百朗德生物科技(海门)有限公司 A kind of cosmetic composition and preparation method thereof with moisturizing senile-resistant efficacy
CN117883340A (en) * 2024-01-09 2024-04-16 广州市脊柱医学研究中心 A method for preparing composition containing multiple natural plant components and skin care product thereof
CN117883340B (en) * 2024-01-09 2024-08-16 广州市脊柱医学研究中心 A method for preparing composition containing multiple natural plant components and skin care product thereof

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Application publication date: 20180216