CN107157874A - A kind of Chinese medicine composition and its application and cosmetics - Google Patents
A kind of Chinese medicine composition and its application and cosmetics Download PDFInfo
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- CN107157874A CN107157874A CN201710346279.2A CN201710346279A CN107157874A CN 107157874 A CN107157874 A CN 107157874A CN 201710346279 A CN201710346279 A CN 201710346279A CN 107157874 A CN107157874 A CN 107157874A
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- chinese medicine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine composition and its application and cosmetics, it is related to daily cosmetics field.The Chinese medicine composition that the present invention is provided is formulated with natural Chinese traditional medicines extract, while have whitening, sun-proof, moisturizing effect, and safely, have no side effect, the peat-reek with the fruit of Chinese magnoliavine.It can be used conveniently to prepare with whitening, sun-proof and moisture-keeping function skin care formulation and cosmetics etc..
Description
Technical field
The present invention relates to daily cosmetics field, in particular to a kind of Chinese medicine composition and its application and cosmetics.
Background technology
At present, the species of cosmetics present on market is various, and different its functions of cosmetics or effect is different, for example, have
It is whitening, sun-proof, moisturizing, anti-acne, anti-aging etc..But, the cosmetics being integrated with a variety of functions are fewer
See, and existing cosmetics are made with chemical raw material more, dangerous, side effect is big.
In consideration of it, special propose the present invention.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition, the Chinese medicine composition has whitening simultaneously, it is sun-proof and
Effect of moisturizing, is used as the raw material of cosmetics, with safety, Small side effects feature.
Another object of the present invention is to provide application of the above-mentioned Chinese medicine composition in skin care formulation is prepared.Prepared
Skin care formulation has whitening, sun-proof, moisturizing effect.
Another object of the present invention is to provide application of the above-mentioned Chinese medicine composition in cosmetics are prepared.Prepared change
Cosmetic has whitening, sun-proof, moisturizing effect.
Another object of the present invention is to provide a kind of cosmetics, it contains above-mentioned Chinese medicine composition.
What the present invention was realized in：
A kind of Chinese medicine composition, it includes ginseng extract, Astragalus Root P.E, Rhizoma Polygonati Odorati extract and fruit of Chinese magnoliavine essential oil.
Application of the above-mentioned Chinese medicine composition in skin care formulation is prepared.
Application of the above-mentioned Chinese medicine composition in cosmetics are prepared.
A kind of cosmetics, it contains above-mentioned Chinese medicine composition.
Compared with prior art, the beneficial effects of the invention are as follows：
The Chinese medicine composition that the present invention is provided includes ginseng extract, Astragalus Root P.E, Rhizoma Polygonati Odorati extract and the fruit of Chinese magnoliavine
Essential oil, is formulated with natural Chinese traditional medicines extract, while having whitening, sun-proof, moisturizing effect, and is made safely, without pair
With, the peat-reek with the fruit of Chinese magnoliavine.It can apply to prepare the fields such as skin care formulation, cosmetics.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, are the conventional production that can be obtained by commercially available purchase
Product.
A kind of Chinese medicine composition of the embodiment of the present invention and its application and cosmetics are specifically described below.
On the one hand, the invention provides a kind of Chinese medicine composition, the Chinese medicine composition can have as raw material for being made
Whitening, sun-proof, moisture-keeping function cosmetics or skin care item.The Chinese medicine composition includes ginseng extract, Astragalus Root P.E, radix polygonati officinalis
Extract and fruit of Chinese magnoliavine essential oil.
Ginseng is the valuable ingredient of traditional Chinese medicine of famous China and foreign countries, and ginsenoside can improve Skin Cell radical scavenging activity, reduce certainly
Accumulated by base, it is to avoid skin comes to harm, destroyed.There is research display to find ginsenoside using D- galactolipins mice aging model
High dose group makes in exhausted mining areas skin caused by D- galactolipins that SOD vigor, hydroxyproline content are significantly raised, and MDA contains
Amount is significantly reduced, and CAT, GSH-Px vigor are significantly raised in blood, and difference has conspicuousness, illustrates ginsenoside to D- galactolipins institute
Aging mice skin has obvious anti-aging effects.Ginsenoside can increase Skin Cell antioxidation activity, and reduction is shone by UVB
Penetrate and cause photooxidation.There is research to show that Panaxatriol saponin Rb1 and Rg1 etc. can dramatically increase UVB irradiation in vitro culture skins
Intracellular antioxidase SOD, GSH and CAT activity, reduce MDA generation.Black of the ginsenoside Rb1 to melanocyte
Plain complex functionality has inhibitory action, and its possible mechanism is：Ginsenoside Rb1 has suppression to make to the NOS activity of melanocyte
With so as to influence intracellular NO to synthesize, mediating path through NO signals, play its immunoregulation function.
Radix Astragali flavone can not only remove free radical and induce membrane lipid peroxidatio, and to hydrogen peroxide or gamma-rays institute
DNA fracture damage is caused to have the protection effect of highly significant.Studies have reported that Astragaloside IV, which has, improves wrinkle and non-creped skin
The effect of skin biological characteristics of fibroblasts, prevents the production of wrinkle.Study display thin with Astragaloside IV pretreatment HaCaT
Born of the same parents, cytoactive only declines 7%~20% after UVB irradiations, and inflammatory cytokine TNF-α, IL-6 secretions significantly reduce (P<
0.05), apoptosis rate is remarkably decreased (P<0.05), hence it is demonstrated that Astragaloside IV has light-protection energy, UVB can be mitigated to skin
The damaging action of skin keratinocyte.
Radix polygonati officinalis medicinal history is long,《Sheng Nong's herbal classic》Be classified as top grade, call its " long term usage goes to face black dry, good color, moisten,
Make light of one's life by commiting suicide not old ", both：Radix polygonati officinalis has moist skin, made light of one's life by commiting suicide not always, can control maiden's colour of skin droop.Liu Ning is made of Rhizoma Polygonati Odorati extract
Facial mask, therapeutic intervention is carried out to dry skin female face, it is found that radix polygonati officinalis facial mask has to dry skin women Face and cheek water content
The effect that positivity is intervened, can definitely improve dry skin water content, and few side effects.
Fructus Schisandrae Chinensis volatile oil main component is terpenoid.Identified studies have reported that being separated from schisandra plant
200 compositions, including 34 triterpenes components, its structure is mostly lanostane-type.Fructus Schisandrae Chinensis volatile oil does not contain aldehyde
And ketones component, they study show volatile oil largely for ter penoidses (including monoterpenes, oxygen-containing monoterpenes, sesquiterpenoids,
Oxygen-containing sesquiterpenoids), still there are the oxydants such as a small amount of alcohol, acid in addition.Have been reported that to the dry fruit of fructus schisandrae through vapor
Obtained volatile oil is distilled, GC-MS qualitative and quantitative analysis is carried out, 81 components are detected altogether.50 compounds therein are identified, it is right
Wherein 5 compositions have carried out qualitative, quantitative determination, and wherein main component has：B-Myrcena, C- cadinenes, D- cadinenes, flores aurantii
The tertiary alcohol, D- cadinols.
Based on this, the Chinese medicine composition that provides of the present invention with natural Chinese traditional medicines extract ginseng extract, Astragalus Root P.E,
Rhizoma Polygonati Odorati extract and fruit of Chinese magnoliavine essential oil are formulated, with whitening, sun-proof, moisturizing effect, and safely, have no side effect simultaneously
Peat-reek with the fruit of Chinese magnoliavine.
Further, in some embodiments of the present invention, it includes by weight：0.1-1 parts of ginseng extract,
0.1-1 parts of 2-3 parts of Astragalus Root P.E, 20-30 parts of Rhizoma Polygonati Odorati extract and fruit of Chinese magnoliavine essential oil.It is formulated using aforementioned proportion
The whitening of Chinese medicine composition, sun-proof, moisturizing effect are good.Wherein, fruit of Chinese magnoliavine essential oil boiling point under conditions of normal temperature, normal pressure is less than
180℃。
Further, in some embodiments of the present invention, above-mentioned ginseng extract, Astragalus Root P.E, radix polygonati officinalis are extracted
Thing is water extract.
Further, in some embodiments of the present invention, above-mentioned fruit of Chinese magnoliavine essential oil can be made by the following method：With
The fruit of Chinese magnoliavine is raw material, and magnolia vine fruit oil is obtained through squeezing or the method such as carbon dioxide supercritical extraction, obtain magnolia vine fruit oil through distillation,
After the methods such as decompression molecular distillation, short-range molecular distillation are refined, fruit of Chinese magnoliavine essential oil is obtained.Certainly, fruit of Chinese magnoliavine essential oil can also lead to
Market is crossed to be commercially available.
Further, in some embodiments of the present invention, above-mentioned Chinese medicine composition also includes emulsifying agent.
On the other hand, the application the invention provides above-mentioned Chinese medicine composition in skin care formulation is prepared.
For example, the excipient by above-mentioned Chinese medicine composition in proportion with conventional cosmetic is mixed for beautifying skin
Repair the skin conditioner of the function such as with whitening, sun-proof, moisturizing.
The type of the skin conditioner can be the various forms of injection, face cream, emulsion, aqueous or conventional cosmetics；Either
According to purpose classification skin care and beauty all kinds of postpartum cosmetics, including but not limited to cleansing cream, cleansing soap, cleaning
Breast, facial mask, toner, massage cream, emulsion, nourishing cream, cosmetic cream, foundation cream or muffin etc..
Further, in above-mentioned application, skin care formulation also contains excipient.
Further, in above-mentioned application, by weight percentage, 1%~50% Chinese medicine group is contained in skin care formulation
Compound.Preferably, content of the Chinese medicine composition in skin care formulation is 25%.
Another further aspect, the invention provides application of the above-mentioned Chinese medicine composition in cosmetics are prepared.
Yet another aspect, the invention provides a kind of cosmetics (or skin care item), it contains above-mentioned Chinese medicine composition.
The feature and performance to the present invention are described in further detail with reference to embodiments.
Embodiment 1
The Chinese medicine composition that the present embodiment is provided, it includes following component：Ginseng extract 0.2kg, Astragalus Root P.E
2kg, Rhizoma Polygonati Odorati extract 20kg, fruit of Chinese magnoliavine essential oil 0.1kg and emulsifying agent.
The Chinese medicine composition that the present embodiment is provided is prepared via a method which：
By 0.2kg ginseng extracts, after 2kg Astragalus Root P.Es and 20kg Rhizoma Polygonati Odorati extracts are sufficiently mixed, addition is gone in right amount
Ionized water, stirs, and then adds 0.1kg fruit ofs Chinese magnoliavine essential oil and emulsifying agent, and stirring is equal.
Embodiment 2
The Chinese medicine composition that the present embodiment is provided, it includes following component：
Ginseng extract 1kg, Astragalus Root P.E 3kg, Rhizoma Polygonati Odorati extract 30kg, fruit of Chinese magnoliavine essential oil 1kg and emulsifying agent.
The Chinese medicine composition that the present embodiment is provided is prepared via a method which：
By 1kg ginseng extracts, after 3kg Astragalus Root P.Es and 30kg Rhizoma Polygonati Odorati extracts are sufficiently mixed, deionized water is added,
Stir, then add 1kg fruit ofs Chinese magnoliavine essential oil and emulsifying agent, stirring is equal.
Embodiment 3
The Chinese medicine composition that the present embodiment is provided, it includes following component：
Ginseng extract 0.1kg, Astragalus Root P.E 2kg, Rhizoma Polygonati Odorati extract 30kg, fruit of Chinese magnoliavine essential oil 0.5kg and emulsification
Agent.
The Chinese medicine composition that the present embodiment is provided is prepared via a method which：
By 0.1kg ginseng extracts, after 2kg Astragalus Root P.Es and 30kg Rhizoma Polygonati Odorati extracts are sufficiently mixed, addition is gone in right amount
Ionized water, stirs, and then adds 0.5kg fruit ofs Chinese magnoliavine essential oil and emulsifying agent, and stirring is equal.
Embodiment 4
Present embodiments provide it is a kind of have whitening, sun-proof, moisture-keeping function skin care formulation, it is prepared as follows.
The Chinese medicine composition that Example 3 is provided is by weight percentage the 1% ratio excipient conventional with cosmetics
Mixing, you can the skin care formulation repaired available for beautifying skin is made.
Experimental example 5
5.1 whitenings are tested
5.1.1 the Chinese medicine composition using the offer of embodiment 2 is as sample, with 1640 culture mediums containing 10% calf serum
It is diluted, is configured to respectively containing 5%, 10%, 20% Chinese medicine composition sample solution as solvent；Using ursin as
Positive control medicine, is configured to containing 5%, 10%, 20% ursin solution respectively.
5.1.2 by cultured melanocyte B16, adjustment cell concentration is 2 × 105Individual/mL, 96 orifice plates add per hole
100uL adjusts the nutrient solution of cell concentration.37 DEG C, 5%CO2Incubator culture 24 hours.
5.1.3 after supporting 24 hours, incline culture medium, adds and contains the Chinese medicine composition sample solution 100uL with postponing, its
Middle sample A, sample B and each 20 hole of each concentration of ursin, while setting blank control.37 DEG C, 5%CO2Incubator culture 24
Hour.
5.1.4 support and terminate preceding 4 hours, add MTT 20uL/ holes, culture end is inclined nutrient solution, addition DMSO 150uL/
Hole, is vibrated 10 minutes, and absorbance is surveyed under ELIASA 540nm wavelength.
5.1.5 analysis finds Chinese medicine composition sample solution concentration at 10%, to melanocyte B16 propagation have compared with
Strong inhibitory action, inhibiting rate is respectively 31.78%, while having with the inhibiting rate (14.64%) of the ursin of same concentration aobvious
Difference is write, shows that the Chinese medicine composition that embodiment 2 is provided has whitening effect, and whitening effect is notable.
5.2 sun-proof experiments
The skin conditioner prepared by Chinese medicine composition provided with embodiment 2 and 3 carries out sun-proof contrast test, while observing it
UV protection effect and adverse reaction to skin.
It is ignorant to product composition using mono blind method, i.e. subject, subject is grouped at random, respectively common sunscreen
White group (a), adds the product group (b) of the Chinese medicine composition of embodiment 2, adds the product group (c) of the Chinese medicine composition of embodiment 3, general
Logical face cream group (e).Every group of 10 people, the daily early upper surface portion of subject smears different product 1 time by group.To overall sun-proof after one week
Effect is evaluated.Sun-proof result is divided into Three Estate：DeGrain (×), effect is general (O), and effect is significantly (√).Comment
Valency method：The people of make up artist 5 is chosen as judging panel, every judging panel is at the scene without under AC conditions, according to subject's blee, skin
The sun-proof grade of the independent evaluation test sample of skin situation.
Conclusion：Using after the suncream for adding Chinese medicine Chinese medicine composition of the present invention, sun-proof result is notable, with compareing after use
Compare, skin of face bleaches, skin colour brightens.Being irritating to the skin property of this compound formulation is not found.There is 1 people to have slightly mistake
The red phenomenon of itching of quick, skin, after disabling 1 day, allergic symptom disappears.
5.3 moisturizings are tested
Detection method referenced patent application number is 2015106795492 patent application.Specifically, selection 36 is tested
Person, in humidity identical environment, is divided into 4 groups, every group of 9 people, group 1 smears the Chinese medicine composition of embodiment 1；Group 2, which is smeared, to be implemented
The Chinese medicine composition of example 2；Group 3 smears the Chinese medicine composition of embodiment 3；Group 4 smears vaseline.Daily with 1.5 μ l/cm2Smear
Even density coating inner forearm face (is cleaned, daily early 8 points and late 8 points each one before smearing every time with gentle cleaning agent twice
It is secondary), continuous 30 smear testing result behind day, and as a result contrast is represented using the effect after preceding and use with average value.
Using the moisture testers of Corneometer CM 825.It is measured unit used and expressed with A.C.U.
(Arbitrarym, its value falls within 30-40CapacitanceUnits), measurement range is from 0 to 120A.C.U., and these values are relative
In the water content of epicuticle, the depth of measurement is about that 20-40A.C.U. is Dry, and is that height contains in more than 120A.C.U.
Water skin.Test result is shown in Table 1 after one month.
Table 1
| Group | Before use | After 30 days |
| Group 1 | 73 | 89c |
| Group 2 | 74 | 98a |
| Group 3 | 72 | 90b |
| Group 4 | 73 | 81d |
Note：Lowercase represents significant difference, P<0.05.
It can be seen that from the result of table 1, using Chinese medicine composition provided in an embodiment of the present invention, its moistening effect is significantly higher than all
Intellectual circle is preferable.
To sum up, the Chinese medicine composition that the present invention is provided includes, with natural Chinese traditional medicines extract ginseng extract, astragalus extraction
Thing, Rhizoma Polygonati Odorati extract and fruit of Chinese magnoliavine essential oil are formulated, while have whitening, sun-proof, moisturizing effect, and safely, nothing
Side effect, the peat-reek with the fruit of Chinese magnoliavine.It can apply to prepare the fields such as skin care formulation, cosmetics.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, for the skill of this area
For art personnel, the present invention can have various modifications and variations.Within the spirit and principles of the invention, that is made any repaiies
Change, equivalent substitution, improvement etc., should be included in the scope of the protection.
Claims (10)
1. a kind of Chinese medicine composition, it is characterised in that it includes ginseng extract, Astragalus Root P.E, Rhizoma Polygonati Odorati extract and five
Taste essential oil.
2. Chinese medicine composition according to claim 1, it is characterised in that it includes by weight：The ginseng is extracted
0.1-1 parts of thing, described Astragalus Root P.E 2-3 parts, described Rhizoma Polygonati Odorati extract 20-30 parts and 0.1-1 parts of the fruit of Chinese magnoliavine essential oil.
3. the Chinese medicine composition according to any one of claim 1-2, it is characterised in that the ginseng extract, described
Astragalus Root P.E and the Rhizoma Polygonati Odorati extract are each water extract.
4. the Chinese medicine composition according to any one of claim 1-2, it is characterised in that the fruit of Chinese magnoliavine essential oil is normal
Boiling point is less than 180 DEG C under conditions of temperature, normal pressure.
5. the Chinese medicine composition according to any one of claim 1-2, it is characterised in that the Chinese medicine composition also includes
Emulsifying agent.
6. application of the Chinese medicine composition any one of claim 1-5 in skin care formulation is prepared.
7. application according to claim 6, it is characterised in that the skin care formulation also contains excipient.
8. the application according to claim 6 or 7, it is characterised in that the Chinese medicine composition is in the skin care formulation
Mass percent is 1-50%.
9. application of the Chinese medicine composition any one of claim 1-5 in cosmetics are prepared.
10. a kind of cosmetics, it is characterised in that it contains the Chinese medicine composition any one of claim 1-5.
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| CN201710346279.2A CN107157874A (en) | 2017-05-16 | 2017-05-16 | A kind of Chinese medicine composition and its application and cosmetics |
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| CN201710346279.2A CN107157874A (en) | 2017-05-16 | 2017-05-16 | A kind of Chinese medicine composition and its application and cosmetics |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108714112A (en) * | 2018-06-12 | 2018-10-30 | 无限极（中国）有限公司 | Composition and the moisturizing containing the composition and/or oxidation resistant cosmetics |
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| CN106551888A (en) * | 2016-11-17 | 2017-04-05 | 长沙玉容本草保健食品有限责任公司 | Anti-ageing anti-wrinkle face cream of a kind of beautiful face and preparation method thereof |
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2017
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|---|---|---|---|---|
| CN101129325A (en) * | 2007-07-28 | 2008-02-27 | 惠中兴 | Whitening speckle-removing spot-removing nourishing powder |
| CN106309263A (en) * | 2016-08-09 | 2017-01-11 | 郑州景鸿畜牧科技有限公司 | Plant whitening nutritional night cream |
| KR101714543B1 (en) * | 2016-09-02 | 2017-03-13 | 강원대학교산학협력단 | Aroma composition for psycholigical stability and reducing stress comprising Schisandra chinensis essential oil and Angelica gigas essential oil as effective component |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108714112A (en) * | 2018-06-12 | 2018-10-30 | 无限极（中国）有限公司 | Composition and the moisturizing containing the composition and/or oxidation resistant cosmetics |
| CN108714112B (en) * | 2018-06-12 | 2021-04-27 | 无限极（中国）有限公司 | Composition and moisturizing and/or antioxidant cosmetic containing same |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170915 |
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| RJ01 | Rejection of invention patent application after publication |