CN103735700A - Medicinal bath preparation for treating sheep ectoparasite and preparation method thereof - Google Patents
Medicinal bath preparation for treating sheep ectoparasite and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicinal bath preparation for treating sheep ectoparasite and a preparation method thereof. The bath preparation is mainly prepared from clove, castor bean, immature bitter orange, tobacco stem, pepper, sophora flavescens, gallnut, broom cypress fruit, fructus cnidii, camphor, ailanthus altissima, pumpkin seed and macleaya cordata. Sulfur powder and alum powder are added into the medicinal bath preparation; realgar is added into the medicinal bath preparation. The medicinal bath preparation can be used for effectively killing sheep ectoparasite in time, and has a remarkable effect in preventing and treating sheep ectoparasite infection, killing parasite eggs, cleaning itch-mite, louse, flea, tick and other parasite sources in the environment.
Description
Technical field
The present invention relates to a kind of sheep vermin medicine for the treatment of, relate in particular to the treatment verminal Medicatedbath lotion of sheep and compound method.
Background technology
Sheep vermin comprises acaricide, louse, flea, Ticks etc., belongs to chronic disease, the equal easy infection of various stage sheep.Ill sheep loss of appetite, poor growth, worm source is spread soon, and infectious rate is high, can make infected animal fertility performance decline, and digests and assimilates function and reduces, and even causes individual or large quantities of death, to sheep husbandry, causes economic loss in various degree.For the vermiontic treatment of sheep, current main larger chemical productss of toxicity such as the macrolide antibiotics such as avilamycin, ivermectin and metrifonate that use, take the modes such as intramuscular injection, for oral administration, partial smearing, treats not thoroughly, easily recur.Utilize medicated bath pools, with medicament preparating liquid is bathed sheep, is the essential measure of prevention and treatment sheep ectoparasitic infection, purification worm's ovum.Bathe at present the most of medicines such as 2% metrifonate solution, 2% ivermectin solution that adopt of sheep medicament, these medicines are widely used and have brought serious " 3R " problem (residual, resistance, again repeatedly), long-term a large amount of use the drug residue, Drug resistance and the environmental hazard thereof that produce to cause people's common concern, in the urgent need to the bathing medicine agent of safety, efficient, low toxicity.Along with the enhancing of health of people environmental consciousness,, low toxicity light to environmental hazard, unlikely residual, dominant direction that natural source medicine that be difficult for producing drug resistance becomes parasiticide development.Chinese medicine, especially the chemical composition of plant source Chinese medicine is various, and effect has a concertedness, for the treatment of combatting ectoparasites disease, has many target spots, the easy feature such as degraded, meets the theory of people's environmental protection.It is less that professional treatment sheep vermin is bathed agent research, can not meet the needs of scale Mutton Sheep Industry development.Therefore, efficient, the low toxicity of research and development, low-residual and with the treatment vermin medicament of environmentally compatible be current herding worker's urgent task.
Summary of the invention
The object of this invention is to provide a kind of verminal Medicatedbath lotion of sheep and compound method for the treatment of, can kill timely and effectively sheep vermin, to prevention and treatment sheep ectoparasitic infection, kill parasite egg, the parasite source effects such as environment purification acaricide, louse, flea, Ticks are remarkable.
For achieving the above object, the technical solution used in the present invention is:
Treat the verminal Medicatedbath lotion of sheep, it is characterized in that: Medicatedbath lotion is mainly comprised of Flos Caryophylli, Semen Ricini, Fructus Aurantii Immaturus, cabo, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis, Galla Chinensis, the Fructus Kochiae, Fructus Cnidii, Camphora, ailanthus altissima (mill.) swingle skin, Semen Cucurbitae, Herba Macleayae Cordatae.
The verminal Medicatedbath lotion for the treatment of sheep according to described, is characterized in that: in described Medicatedbath lotion, add Cosan and Alumen powder.
The verminal Medicatedbath lotion for the treatment of sheep according to described, is characterized in that: in described Medicatedbath lotion, add Realgar.
A kind of collocation method of described Medicatedbath lotion, it is characterized in that: the first step, Flos Caryophylli 60g, Semen Ricini 50g, Fructus Aurantii Immaturus 40g, cabo 60g, Pericarpium Zanthoxyli 80g, Radix Sophorae Flavescentis 30g, Galla Chinensis 50g, Fructus Kochiae 30g, Fructus Cnidii 20g, Camphora 50g, ailanthus altissima (mill.) swingle skin 50g, Semen Cucurbitae 40g, Herba Macleayae Cordatae 30g are first used to cold water soak 20 minutes, be watered 2000ml, temperature fire decocts 40 minutes, remove slag and stay liquid, obtain medicinal liquid 1000ml, become a agent; Second step, mixes Cosan 280g and Alumen powder 150g to become b agent, and Realgar 70g forms c agent; The 3rd step, when a agent is cooled to 70 ℃-80 ℃, puts into a agent by b agent, fully stirs, and while being cooled to 20 ℃-30 ℃, c agent is added, and after fully stirring, is finished product medicament, standby.
Advantageous effect of the present invention is: can kill timely and effectively sheep vermin, to prevention and treatment sheep ectoparasitic infection, kill parasite egg, the parasite source effects such as environment purification acaricide, louse, flea, Ticks are remarkable.
The specific embodiment
Below in conjunction with specific embodiment, the invention will be further described:
Treat the verminal Medicatedbath lotion of sheep, it is characterized in that: Medicatedbath lotion is mainly comprised of Flos Caryophylli, Semen Ricini, Fructus Aurantii Immaturus, cabo, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis, Galla Chinensis, the Fructus Kochiae, Fructus Cnidii, Camphora, ailanthus altissima (mill.) swingle skin, Semen Cucurbitae, Herba Macleayae Cordatae.The verminal Medicatedbath lotion for the treatment of sheep according to described, is characterized in that: in described Medicatedbath lotion, add Cosan and Alumen powder.The verminal Medicatedbath lotion for the treatment of sheep according to described, is characterized in that: in described Medicatedbath lotion, add Realgar.A kind of according to the collocation method of described Medicatedbath lotion, it is characterized in that: the first step, Flos Caryophylli 60g, Semen Ricini 50g, Fructus Aurantii Immaturus 40g, cabo 60g, Pericarpium Zanthoxyli 80g, Radix Sophorae Flavescentis 30g, Galla Chinensis 50g, Fructus Kochiae 30g, Fructus Cnidii 20g, Camphora 50g, ailanthus altissima (mill.) swingle skin 50g, Semen Cucurbitae 40g, Herba Macleayae Cordatae 30g are first used to cold water soak 20 minutes, be watered 2000ml, temperature fire decocts 40 minutes, remove slag and stay liquid, obtain medicinal liquid 1000ml, become a agent; Second step, mixes Cosan 280g and Alumen powder 150g to become b agent, and Realgar 70g forms c agent; The 3rd step, when a agent is cooled to 70 ℃-80 ℃, puts into a agent by b agent, fully stirs, and while being cooled to 20 ℃-30 ℃, c agent is added, and after fully stirring, is finished product medicament, standby.
Configuration of the present invention and using method are as described below, 1, Flos Caryophylli 60g, Semen Ricini 50g, Fructus Aurantii Immaturus 40g, cabo 60 g, Pericarpium Zanthoxyli 80 g, Radix Sophorae Flavescentis 30 g, Galla Chinensis 50g, Fructus Kochiae 30g, Fructus Cnidii 20g, Camphora 50g, ailanthus altissima (mill.) swingle skin 50g, Semen Cucurbitae 40g, Herba Macleayae Cordatae 30g are first used to cold water soak 20 minutes, then be watered 2000ml, temperature fire decocts 40 minutes, remove slag and stay liquid, obtain medicinal liquid 1000ml, become a agent; 2, Cosan 280 g and Alumen powder 150 g are mixed into b agent; 3, Realgar 70 g form c agent; When 4, a agent is cooled to 70 ℃-80 ℃, b agent is put into a agent, fully stir; While being then cooled to 20 ℃-30 ℃, c agent is added, after fully stirring, be this finished product medicament, standby.5, finished product medicament is added to clear water in 1% volume ratio (being that every 1000 ml finished product medicaments can add water 99000ml), blend together water suspension, for 500 sheep dippings.During dipping, sheep body is soaked to 2-3 minute in medicinal liquid; Then head is soaked 2-3 time rapidly to each 1-2 second.
Each taste composition of a agent all has obvious parasiticide and demodicid mite is active, and different pharmaceutical worm effective site and effect are different, multiple active drug associating, get long keep away short, the toxic removing of invigorating blood circulation, heat-clearing and toxic substances removing, killing parasites for relieving itching, the multiplication of Pesticidal and sterilizing effect, for alleviating, vermin symptom effect is remarkable; The acid of b agent sulfur nature and flavor, temperature, slightly poisonous, its effect is removing toxic substances, parasite killing, cures mainly the multiple epizootic diseases such as scabies, louse; Alumen Main Ingredients and Appearance is calomel, property and flavor of peppery and cold, and its effect is that killing parasites for relieving itching also cures mainly scabies etc., can suppress various skin fungus and staphylococcus aureus; C agent Realgar all has counteracting toxic substances, parasite killing, antipruritic effect, in order to effect a permanent cure.
A agent+b agent+c agent, combination and compatibility at specified conditions and temperature, there is the functions such as clearing heat and removing internal wetness, dispelling wind for relieving itching, detoxicating and killing parasites, without Drug resistance, can make this preparation direct reach disease institute, deeply, except sick, reach specimen and all control object, can effectively kill the vermins such as acaricide, be the vermiontic specially good effect good medicine for the treatment of sheep.According to test, this finished product medicament is blended together after water suspension in 1% volume ratio, activity is not less than the drug effect of avilamycin aqueous solution and 2% the metrifonate solution of 2mg/L, and manufacture, using method are simple, and effective time is quick.The present invention is simple in veterinary clinic application, numerous raisers can prepare voluntarily, treatment voluntarily, evident in efficacy, have natural, efficient, toxic and side effects is little, safe, the residual plurality of advantages such as few, and raw material sources are wide, cost is low, technique is simple, there is good economic benefit and social benefit, can extensive use when treatment sheep vermin.
That this Medicatedbath lotion is used contrast situation with ivermectin powder, metrifonate powder below:
Select ivermectin powder (manufacturer: Weiyuan, Hebei animal pharmaceutical estate company limited, 20130420), metrifonate powder (manufacturer: farmland, Zhengzhou Chemical Co., Ltd. lot number:, 20130112) and this invention medicament lot number:, ivermectin powder and metrifonate powder are formulated as respectively the medicinal liquid of 2mg/L and 2%, the medicinal liquid that product configuration of the present invention is 1%.
Selection suffers from the boer goat of the parasitic disease such as acaricide and louse, and body weight, age, 15 sheep that the state of an illness is close, be divided into A, B, tri-groups of C, 5 every group at random.Three groups of sheep feeding and management conditions are consistent.The ivermectin medicinal liquid dipping of 2mg/L for A group; The metrifonate medicinal liquid dipping of B group 2%; C organizes the medicinal liquid dipping of the present invention with 1%.Once a day, continuous 28 days.
Observe sheep behavior and dermatosis and score, observe sheep tickle behavior and pathological changes and other behaviors on time, use microscopy acarid, and record dermatosis situation.Dermatosis score value situation is as follows, 0 minute: sick sheep, without tickle and itch, becomes and crust skin without self inflicted injury sexually transmitted disease (STD); 1 minute: low-grade infection, pruritus, without cutin proliferative lesion; 2 minutes: have and thicken on a small quantity canescence crust, limitation extremity and nose; 3 minutes: the coarse dry crusts sample of the canescence pathological changes that skin has bulk to thicken, area is greater than 5cm
2; 4 minutes: special severe infection, violent pruritus, extremity, face, tail, foot all have the crust of bulk hypertrophy, and area surpasses 10cm
2, lose weight.With pocket knife, dip in edge that 50% glycerol gently scrapes crust position to till hemorrhage, put container numbering into, take back lab testing.To the score value of scoring of the pathological changes of acaricide, in testing 0 d, 7 d, each inspection record of 28 d once, microscopy acaricide carries out respectively in 7d, 28 d, the situations such as the clinical spirit of every group of sheep of observation experiment process, appetite, incrustation pathological changes.
7d after dipping, A organizes acaricide lesion score than not front 62.5%, the B of the minimizing group of administration minimizing 53.1%, C group minimizing 93.7%; 28d after administration, A organizes acaricide lesion score than not front 97.5%, the B of the minimizing group of administration minimizing 99.4%, C group minimizing 100%.Through microscopy, 7 d A groups have 1 sheep positive, and B group has 2 sheep positives, and C group does not have the positive, and each is organized cure rate and is respectively 80%, 60%, 100%; Each group of 28 d microscopies is all negative.
The different groups of table 1 are to the vermiontic therapeutic effect of sheep
| Group | Number of elements | 0 d lesion score | 7 d lesion scores | 28 d lesion scores | 7 d microscopies | 28 d microscopies | Behavior tickles | 7d cures number (only) | 7d cure rate (%) |
| A | 5 | 3.2 | 1.2 | 0.08 | + | — | — | 4 | 80 |
| B | 5 | 3.2 | 1.5 | 0.02 | — | — | — | 3 | 60 |
| C | 5 | 3.2 | 0.2 | 0 | — | — | — | 5 | 100 |
28d, A group weightening finish 43.6%, B group weightening finish 24.1%, C group weightening finish 59.1%.Through t check, C group is organized comparing difference significantly (P < 0.01) with A group, B respectively.Refer to table 2.
The different groups of table 2 are treated disease sheep front and back body weight change
Kg、%
| Group | 0 d | 28 d | Weightening finish | Rate of body weight gain |
| A | 16.5±1.45 | 23.7±0.60 | 7.20±0.85 | 43.6 |
| B | 15.8±2.08 | 19.6±1.90 | 3.80±0.62 | 24.1 |
| C | 15.9±1.80 | 25.3±2.70 | 9.40±0.28 | 59.1 |
It is normal that each organizes the clinical spiritual expression of sheep experimentation, without improper performances such as poisoning, inappetence.At medication 10d-15d crust, start to come off, and the behavior that respectively tickles disappears, after grow newborn red skin, each group sampling check demodicid mite that lives is negative.
Embodiment recited above is described the preferred embodiment of the present invention; not design of the present invention and protection domain are limited; do not departing under the prerequisite of design concept of the present invention; various modification and improvement that in this area, common engineers and technicians make technical scheme of the present invention, all should fall into protection scope of the present invention.
Claims (4)
1. the verminal Medicatedbath lotion for the treatment of sheep, is characterized in that: Medicatedbath lotion is mainly comprised of Flos Caryophylli, Semen Ricini, Fructus Aurantii Immaturus, cabo, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis, Galla Chinensis, the Fructus Kochiae, Fructus Cnidii, Camphora, ailanthus altissima (mill.) swingle skin, Semen Cucurbitae, Herba Macleayae Cordatae.
2. the verminal Medicatedbath lotion for the treatment of sheep according to claim 1, is characterized in that: in described Medicatedbath lotion, add Cosan and Alumen powder.
3. the verminal Medicatedbath lotion for the treatment of sheep according to claim 1 and 2, is characterized in that: in described Medicatedbath lotion, add Realgar.
4. the collocation method of Medicatedbath lotion described in a claim 1-3, it is characterized in that: the first step, Flos Caryophylli 60g, Semen Ricini 50g, Fructus Aurantii Immaturus 40g, cabo 60g, Pericarpium Zanthoxyli 80g, Radix Sophorae Flavescentis 30g, Galla Chinensis 50g, Fructus Kochiae 30g, Fructus Cnidii 20g, Camphora 50g, ailanthus altissima (mill.) swingle skin 50g, Semen Cucurbitae 40g, Herba Macleayae Cordatae 30g are first used to cold water soak 20 minutes, be watered 2000ml, temperature fire decocts 40 minutes, remove slag and stay liquid, obtain medicinal liquid 1000ml, become a agent; Second step, mixes Cosan 280g and Alumen powder 150g to become b agent, and Realgar 70g forms c agent; The 3rd step, when a agent is cooled to 70 ℃-80 ℃, puts into a agent by b agent, fully stirs, and while being cooled to 20 ℃-30 ℃, c agent is added, and after fully stirring, is finished product medicament, standby.
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| CN105796802A (en) * | 2016-04-11 | 2016-07-27 | 马鞍山市金农牧业有限公司 | External spray for goat Sarcoptidosis |
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| CN106902206A (en) * | 2017-03-14 | 2017-06-30 | 滁州新源农业科技有限公司 | A kind of pulvis and preparation method for preventing and treating pig epidermis parasite |
| CN107927001A (en) * | 2017-11-27 | 2018-04-20 | 桂林斯泰硕农农业科技有限公司 | The method for preventing Bu Funa oleanders aphid evil |
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