CN1768841A - Chinese medicinal compound formulation for treating skin disease - Google Patents
Chinese medicinal compound formulation for treating skin disease Download PDFInfo
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- CN1768841A CN1768841A CNA2005100196696A CN200510019669A CN1768841A CN 1768841 A CN1768841 A CN 1768841A CN A2005100196696 A CNA2005100196696 A CN A2005100196696A CN 200510019669 A CN200510019669 A CN 200510019669A CN 1768841 A CN1768841 A CN 1768841A
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Abstract
The invention provides a Chinese medicinal compound preparation for treating skin diseases, which is prepared from the raw materials including safflower, clove, pricklyash peel, atractylodes rhizome, corktree bark, broom cypress fruit, Chinese dittany bark, roor of sessile stemona, Chinese mugwort leafmulberry leaf, cortex pseudolaricis, cnidium fruit, flavescent sophora root, centipede, camphor, 2-hydroxybenzoic acid, benzene carboxylic acid, dimethyl sulfoxide and 50-60% of ethanol.
Description
Technical field
The present invention relates to the dermopathic medicament of a kind of treatment, be specifically related to a kind of compound Chinese medicinal preparation for the treatment of skin pruritus.
Background technology
Dermopathic sickness rate China south crowd up to more than 80%.In high temperature humid areas such as China the Yellow River, the Yangtze river basin and subtropical zone, the Middle East, Europe, America, most people suffer from the different tinea of weight, pruritus, and thousands of people endures dermopathic torment to the fullest extent.
The kind of the medicament of existing treatment skin pruritus (as dermatosiss such as the tinea manuum, tinea pedis, tinea corporis) is more, as: " the clean health lotion of skin " that Qinghai Gela Dandong Pharmaceutical Industry Co., Ltd. produces has heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation, pain relieving, antipruritic, be used for acute and chronic dermatitis, skin pruritus, the tinea manuum, tinea pedis." skin-cleaning and itch-stopping tincture " that Guizhou Tongkang Pharmaceutical Industry Co., Ltd. produces has removing pathogenic heat from blood and toxic substance from the body, and dispelling wind for relieving itching is used for the psoriasis due to the heat in blood wind-dryness, and the tinea skin pruritus.Medicament in the external of existing treatment skin pruritus, as the patent No.: 98112960.9, denomination of invention is: Fukangmei tinea ointment.Weak point is: use every day repeatedly, a couple of days is a course of treatment, and curative effect is slow, to cure effective percentage not high.
Summary of the invention
The object of the present invention is to provide that a kind of consumption is few, curative effect is fast, cure the high dermopathic compound Chinese medicinal preparation of treatment of effective percentage.
To achieve these goals, technical scheme of the present invention is: the dermopathic compound Chinese medicinal preparation of a kind of treatment, it is characterized in that it comprises that Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide and concentration (weight) are that 50～60% ethanol raw material is prepared from, the shared parts by weight of each component are:
Flos Carthami 2.5～2.8, Flos Caryophylli 2.5～2.8, Pericarpium Zanthoxyli 4.5～5.5, Rhizoma Atractylodis 4.5～5.5,
Cortex Phellodendri 4.5～5.5, the Fructus Kochiae 4.5～5.5, Cortex Dictamni 4.5～5.5, the Radix Stemonae 9～11,
Folium Artemisiae Argyi 9～11, Cortex Pseudolaricis 9～11, Fructus Cnidii 14～16, Radix Sophorae Flavescentis 19～21,
Scolopendra 40～90, Camphora 9～11, salicylic acid 19～21, benzoic acid 34～36,
Dimethyl sulfoxide 27～33, ethanol 225～275.
Described each component optimum weight umber is:
Flos Carthami 2.6, Flos Caryophylli 2.6, Pericarpium Zanthoxyli 5.0, Rhizoma Atractylodis 5.0,
Cortex Phellodendri 5.0, the Fructus Kochiae 5.0, Cortex Dictamni 5.0, the Radix Stemonae 10,
Folium Artemisiae Argyi 10, Cortex Pseudolaricis 10, Fructus Cnidii 15, Radix Sophorae Flavescentis 20,
Scolopendra 60, Camphora 10, salicylic acid 20, benzoic acid 35,
Dimethyl sulfoxide 30, ethanol 250.
Also comprise jasmin essence in the described component, the shared parts by weight of jasmin essence are: 0.5～0.8.
Described a kind of preparation method for the treatment of dermopathic compound Chinese medicinal preparation comprises the steps:
1). raw material is chosen: by the shared parts by weight of each component be: Flos Carthami 2.5～2.8, Flos Caryophylli 2.5～2.8, Pericarpium Zanthoxyli 4.5～5.5, Rhizoma Atractylodis 4.5～5.5, Cortex Phellodendri 4.5～5.5, the Fructus Kochiae 4.5～5.5, Cortex Dictamni 4.5～5.5, the Radix Stemonae 9～11, Folium Artemisiae Argyi 9～11, Cortex Pseudolaricis 9～11, Fructus Cnidii 14～16, Radix Sophorae Flavescentis 19～21, Scolopendra 40～90, Camphora 9～11, salicylic acid 19～21, benzoic acid 34～36, dimethyl sulfoxide 27～33, concentration (weight) is that 50～60% ethanol 225～275 is chosen Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide and ethanol.
2). Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis and Scolopendra are ground into coarse powder, contain in the container, and add parts by weight and be: 160～180 parts, concentration (weight) are 50～60% ethanol, Mi Gai, flooded seven, and collected impregnation liquid; The concentration that adds for the second time surplus is 50～60% ethanol in the slag charge of dipping for the first time, and Mi Gai flood three, collected impregnation liquid, with the first time impregnation liquid merge, left standstill filtration 24 hours.
3). get filtrate, camphorate, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence, mixing promptly gets product.
The present invention adopts above-mentioned component and proportioning, Cortex Dictamni: heat clearing and damp drying, the detoxifcation of dispeling the wind; Have the effect of killing parasites for relieving itching, be used for eczema, rubella, scabies skin ulcer leprosy etc.Radix Sophorae Flavescentis: the nature and flavor bitter cold has heat clearing and damp drying, parasite killing, antipruritic effect; Be used for swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.Scolopendra: endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain; Have antalgesic-antipruritic antidotal effect, be used for mosquito bite.Cortex Pseudolaricis: suffering, temperature; Has parasite killing, the itching relieving effect; Be used for the scabies pruritus.Fructus Cnidii: warm in nature, the acrid in the mouth hardship has that dampness is dispeled the wind, the killing parasites for relieving itching effect; Be used for pruritus ani, pruritus vulvae, eczema etc.The Fructus Kochiae: cold in nature, the acrid in the mouth hardship has clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching effect; Be used for pruritus vulvae, eczema and urticaria etc.Benzoic acid: disinfection preservative has killing action to common bacteria, fungus.Pericarpium Zanthoxyli: suffering, temperature has the effect of warming middle-JIAO to relieve pain, killing parasites for relieving itching; Be used for the treatment of the eczema pruritus.Dimethyl sulfoxide: cutaneous permeable agent.Camphora: antipruritic, analgesia and local irritant effect are arranged.Salicylic acid: cutin dissolving softening agent, and antibacterial, itching-relieving action is arranged.Effects such as that the Flos Carthami in the prescription, Flos Caryophylli, Rhizoma Atractylodis, the Radix Stemonae, Cortex Phellodendri and Folium Artemisiae Argyi have is antipruritic, cold expelling, pain relieving.Above-mentioned medicine has synergism together, therefore has the effect of treatment skin pruritus.
The present invention's (trade name: " pruritus logical gram ") has changed that product of the same type uses repeatedly every day, a couple of days is the conventional method of a course of treatment, and beriberi, pruritus, goose palm effective percentage are reached more than 98%, use and once keep half a year at least, even 3-5 does not recur; Compare domestic and international product of the same type, characteristics such as it has, and consumption is little, produce effects is fast, cure rate is high, difficult recurrence in a short time.The present invention both had been different from the strong and stimulating of chemical drugs, and it is slow to be different from the Chinese medicine preparation produce effects again, and its double length of getting both merges the Chinese-western medicine preparation technology, makes this product that unique curative effect be arranged, and has reached advanced international level.The feedback of this product development achievement after medical authoritative department clinical practice and patient's use, evident in efficacy to the tinea manuum, tinea pedis, tinea corporis, easy to use, general itching skin disease also there is positive effect, allow the patient really away from many worries such as the tinea manuum, tinea pedis, tinea corporis.
The using method of product of the present invention: every day 2 times is wiped with " the logical gram of pruritus " direct spray in the clean back of drying, affected part.Notice that this product zest is big, it is too much unsuitable that each spray is applied medicinal lotion or ointment, and mucosa and surrounding skin thereof are avoided usefulness, and there is burning sensation at the place of applying medicinal lotion or ointment during the treatment, and illing skin is rubescent, and the continuous use illing skin comes off.
The specific embodiment
Example 1: the dermopathic compound Chinese medicinal preparation of a kind of treatment, it comprises that Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence and concentration (weight) are that 50～60% ethanol raw material is prepared from, and the shared parts by weight of each component are:
Flos Carthami 2.5, Flos Caryophylli 2.5, Pericarpium Zanthoxyli 4.5, Rhizoma Atractylodis 4.5,
Cortex Phellodendri 4.5, the Fructus Kochiae 4.5, Cortex Dictamni 4.5, the Radix Stemonae 9,
Folium Artemisiae Argyi 9, Cortex Pseudolaricis 9, Fructus Cnidii 14, Radix Sophorae Flavescentis 19,
Scolopendra 40, Camphora 9, salicylic acid 19, benzoic acid 34,
Dimethyl sulfoxide 27, ethanol 225, jasmin essence 0.5.
Described a kind of preparation method for the treatment of dermopathic compound Chinese medicinal preparation comprises the steps:
1). raw material is chosen: by the shared parts by weight of each component be: Flos Carthami 2.5, Flos Caryophylli 2.5, Pericarpium Zanthoxyli 4.5, Rhizoma Atractylodis 4.5, Cortex Phellodendri 4.5, the Fructus Kochiae 4.5, Cortex Dictamni 4.5, the Radix Stemonae 9, Folium Artemisiae Argyi 9, Cortex Pseudolaricis 9, Fructus Cnidii 14, Radix Sophorae Flavescentis 19, Scolopendra 40, Camphora 9, salicylic acid 19, benzoic acid 34, dimethyl sulfoxide 27, jasmin essence 0.5, ethanol 225 is chosen Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence and ethanol.
2). Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis and Scolopendra are ground into coarse powder, contain in the container, and add parts by weight and be: 160 parts, concentration (weight) are 50～60% ethanol, Mi Gai, flooded seven, and collected impregnation liquid; The concentration (weight) that adds for the second time surplus is 50～60% ethanol in the slag charge of dipping for the first time, and Mi Gai flood three, collected impregnation liquid, with the first time impregnation liquid merge, left standstill filtration 24 hours.
3). get filtrate, camphorate, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence, mixing promptly gets product.
Example 2: the dermopathic compound Chinese medicinal preparation of a kind of treatment, it is characterized in that it comprises that Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence and concentration are that 50～60% ethanol raw material is prepared from, the shared parts by weight of each component are:
Flos Carthami 2.6, Flos Caryophylli 2.6, Pericarpium Zanthoxyli 5.0, Rhizoma Atractylodis 5.0,
Cortex Phellodendri 5.0, the Fructus Kochiae 5.0, Cortex Dictamni 5.0, the Radix Stemonae 10,
Folium Artemisiae Argyi 10, Cortex Pseudolaricis 10, Fructus Cnidii 15, Radix Sophorae Flavescentis 20,
Scolopendra 60, Camphora 10, salicylic acid 20, benzoic acid 35,
Dimethyl sulfoxide 30, ethanol 250, jasmin essence 0.6.
Described a kind of preparation method for the treatment of dermopathic compound Chinese medicinal preparation comprises the steps:
1). raw material is chosen: by the shared parts by weight of each component be: Flos Carthami 2.6, Flos Caryophylli 2.6, Pericarpium Zanthoxyli 5.0, Rhizoma Atractylodis 5.0, Cortex Phellodendri 5.0, the Fructus Kochiae 5.0, Cortex Dictamni 5.0, the Radix Stemonae 10, Folium Artemisiae Argyi 10, Cortex Pseudolaricis 10, Fructus Cnidii 15, Radix Sophorae Flavescentis 20, Scolopendra 60, Camphora 10, salicylic acid 20, benzoic acid 35, dimethyl sulfoxide 30, jasmin essence 0.6, ethanol 250 is chosen Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence and ethanol.
2). Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis and Scolopendra are ground into coarse powder, contain in the container, and add parts by weight and be: 180 parts, concentration are 50～60% ethanol, Mi Gai, flooded seven, and collected impregnation liquid; The concentration that adds for the second time surplus is 50～60% ethanol in the slag charge of dipping for the first time, and Mi Gai flood three, collected impregnation liquid, with the first time impregnation liquid merge, left standstill filtration 24 hours.
3). get filtrate, camphorate, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence, mixing promptly gets product.
Example 3: the dermopathic compound Chinese medicinal preparation of a kind of treatment, it comprises that Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence and concentration are that 50～60% ethanol raw material is prepared from, and the shared parts by weight of each component are:
Flos Carthami 2.8, Flos Caryophylli 2.8, Pericarpium Zanthoxyli 5.5, Rhizoma Atractylodis 5.5,
Cortex Phellodendri 5.5, the Fructus Kochiae 5.5, Cortex Dictamni 5.5, the Radix Stemonae 11,
Folium Artemisiae Argyi 11, Cortex Pseudolaricis 11, Fructus Cnidii 16, Radix Sophorae Flavescentis 21,
Scolopendra 90, Camphora 11, salicylic acid 21, benzoic acid 36,
Dimethyl sulfoxide 33, ethanol 275, jasmin essence 0.6.
Described a kind of preparation method for the treatment of dermopathic compound Chinese medicinal preparation comprises the steps:
1). raw material is chosen: by the shared parts by weight of each component be: Flos Carthami 2.8, Flos Caryophylli 2.8, Pericarpium Zanthoxyli 5.5, Rhizoma Atractylodis 5.5, Cortex Phellodendri 5.5, the Fructus Kochiae 5.5, Cortex Dictamni 5.5, the Radix Stemonae 11, Folium Artemisiae Argyi 11, Cortex Pseudolaricis 11, Fructus Cnidii 16, Radix Sophorae Flavescentis 21, Scolopendra 90, Camphora 11, salicylic acid 21, benzoic acid 36, dimethyl sulfoxide 33, jasmin essence 0.6, ethanol 275 is chosen Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence and ethanol.
2). Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis and Scolopendra are ground into coarse powder, contain in the container, and add parts by weight and be: 180 parts, concentration are 50～60% ethanol, Mi Gai, flooded seven, and collected impregnation liquid; The concentration that adds for the second time surplus is 50～60% ethanol in the slag charge of dipping for the first time, and Mi Gai flood three, collected impregnation liquid, with the first time impregnation liquid merge, left standstill filtration 24 hours.
3). get filtrate, camphorate, salicylic acid, benzoic acid, dimethyl sulfoxide, jasmin essence, mixing promptly gets product.
Claims (3)
1. treat dermopathic compound Chinese medicinal preparation for one kind, it is characterized in that it comprises that Flos Carthami, Flos Caryophylli, Pericarpium Zanthoxyli, Rhizoma Atractylodis, Cortex Phellodendri, the Fructus Kochiae, Cortex Dictamni, the Radix Stemonae, Folium Artemisiae Argyi, Cortex Pseudolaricis, Fructus Cnidii, Radix Sophorae Flavescentis, Scolopendra, Camphora, salicylic acid, benzoic acid, dimethyl sulfoxide and concentration are that 50～60% ethanol raw material is prepared from, the shared parts by weight of each component are:
Flos Carthami 2.5～2.8, Flos Caryophylli 2.5～2.8, Pericarpium Zanthoxyli 4.5～5.5, Rhizoma Atractylodis 4.5～5.5,
Cortex Phellodendri 4.5～5.5, the Fructus Kochiae 4.5～5.5, Cortex Dictamni 4.5～5.5, the Radix Stemonae 9～11,
Folium Artemisiae Argyi 9～11, Cortex Pseudolaricis 9～11, Fructus Cnidii 14～16, Radix Sophorae Flavescentis 19～21,
Scolopendra 40～90, Camphora 9～11, salicylic acid 19～21, benzoic acid 34～36,
Dimethyl sulfoxide 27～33, ethanol 225～275.
2. the dermopathic compound Chinese medicinal preparation of a kind of treatment according to claim 1 is characterized in that the shared parts by weight of described each component are:
Flos Carthami 2.6, Flos Caryophylli 2.6, Pericarpium Zanthoxyli 5.0, Rhizoma Atractylodis 5.0,
Cortex Phellodendri 5.0, the Fructus Kochiae 5.0, Cortex Dictamni 5.0, the Radix Stemonae 10,
Folium Artemisiae Argyi 10, Cortex Pseudolaricis 10, Fructus Cnidii 15, Radix Sophorae Flavescentis 20,
Scolopendra 60, Camphora 10, salicylic acid 20, benzoic acid 35,
Dimethyl sulfoxide 30, ethanol 250.
3. the dermopathic compound Chinese medicinal preparation of a kind of treatment according to claim 1 and 2 is characterized in that also comprising in the described component jasmin essence, and the shared parts by weight of jasmin essence are: 0.5～0.8.
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| CN101156939B (en) * | 2006-10-06 | 2011-06-08 | 刘宝环 | A medicine for treating tinea manuum |
| CN101690708B (en) * | 2009-10-15 | 2011-06-15 | 山东益母妇女用品有限公司 | Cleaning and nursing solution for female pudenda and preparation method thereof |
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| CN101690708B (en) * | 2009-10-15 | 2011-06-15 | 山东益母妇女用品有限公司 | Cleaning and nursing solution for female pudenda and preparation method thereof |
| CN102357221A (en) * | 2011-10-21 | 2012-02-22 | 马良玉 | Chinese patent drug lotion for treating fungal infection of hands |
| CN102657731A (en) * | 2012-03-21 | 2012-09-12 | 罗莉 | Medicament for treating acute eczema |
| CN102727800B (en) * | 2012-06-19 | 2013-11-06 | 朱林 | Multi-purpose tinea drug and preparation method thereof |
| CN102727800A (en) * | 2012-06-19 | 2012-10-17 | 朱林 | Multi-purpose tinea drug and preparation method thereof |
| CN102764331B (en) * | 2012-07-30 | 2013-06-12 | 陈丽杰 | External medicine for treating nail ringworm and whitlow |
| CN102764331A (en) * | 2012-07-30 | 2012-11-07 | 陈丽杰 | External medicine for treating nail ringworm and whitlow |
| CN103223132B (en) * | 2013-05-17 | 2014-05-21 | 陈孔春 | Medicine for treating allergic dermatitis and preparation method thereof |
| CN103223132A (en) * | 2013-05-17 | 2013-07-31 | 陈孔春 | Medicine for treating allergic dermatitis and preparation method thereof |
| CN103385927A (en) * | 2013-07-16 | 2013-11-13 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicine composition for the treatment of animal acariasis |
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