CN105561077A - Product for treating dermatitis and eczema and preparation method thereof - Google Patents
Product for treating dermatitis and eczema and preparation method thereof Download PDFInfo
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- CN105561077A CN105561077A CN201610073084.0A CN201610073084A CN105561077A CN 105561077 A CN105561077 A CN 105561077A CN 201610073084 A CN201610073084 A CN 201610073084A CN 105561077 A CN105561077 A CN 105561077A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a product for treating dermatitis and eczema. Every 1000 ml of the finished product is prepared from, by weight, 90-110 g of fructus xanthii, 90-110 g of fructus tribuli, 15-30 g of flos caryophylli, 90-120 g of common cnidium fruits, 3-10 g of pricklyash peels, 40-60 g of fructus gleditsiae sinensis, 90-120 g of rhizoma polygonati, 25-50 g of rhizoma coptidis, 50-70 g of herba houttuyniae, 70-100 g of rhizoma smilacis glabrae, 90-120 g of roots or all-grass of Achyranthes aspera L. and 60-90 g of pericarpium granati. The product is good in treatment effect and free of toxic or side effect.
Description
Technical field
The invention belongs to Chinese medicine health care product technical field, be specifically related to a kind of product and preparation method thereof for the treatment of dermatitis, eczema.
Background technology
Pruritus disease is the commonly encountered diseases of department of dermatologry, and main manifestations is for only having skin pruritus and without constitutional skin lesion, and treatment relative difficulty, easily recurs.Pruritus is one of main subjective symptoms of multiple dermatosis, and itching skin disease mainly comprises skin pruritus, neurodermatitis, papular urticaria, chronic eczema, tinea manus and pedis, scabies, prurigo nodularis and dermatitis aestivale etc.Because the itching skin disease cause of disease is complicated, inducement is more, is department of dermatologry common clinical, frequently-occurring disease, and account for Dermatology Outpatient Department patient's more than 80%, bring considerable distress to patient, quality of life obviously declines.
China's most area is because of the multiple dermatosis of climate reasons, also easily makes original dermatosis increase the weight of.Under high hot weather, wind heat, perspiration drainage difficulty and summer, another common disease-eczema etc. caused skin pruritus, due to pruritus, scratched, and easily causes the infection of staphylococcus, streptococcus and fungus, skin pruritus increases the weight of, causes and fester.Clinically adopt for oral administration and external, current skin pruritus treatment mainly applies antibiotic and hormone, and side effect is very large, and short-term has certain effect more, will recurrent exerbation once stop using, and has certain dependency.
Summary of the invention
Technical problem to be solved by this invention is for above-mentioned the deficiencies in the prior art, provides a kind of product and preparation method thereof controlling treatment dermatitis that is effective, that have no side effect, eczema.
For solving the problems of the technologies described above, the technical solution used in the present invention is, a kind of product for the treatment of dermatitis, eczema, in every 1000ml finished product, the raw material that effective ingredient comprises following weight is made: Fructus Xanthii 90 ~ 110g, Fructus Tribuli 90 ~ 110g, Flos Caryophylli 15 ~ 30g, Fructus Cnidii 90 ~ 120g, Fructus Zanthoxyli 3 ~ 10g, Chinese honey locust (fruit) 40 ~ 60g, Rhizoma Polygonati 90 ~ 120g, Rhizoma Coptidis 25 ~ 50g, Herba Houttuyniae 50 ~ 70g, Rhizoma Smilacis Glabrae 70 ~ 100g, Radix Achyranthis 90 ~ 120g, Pericarpium Granati 60 ~ 90g.
Further, for strengthening the property of medicine, the raw material of following weight is also comprised: volumetric concentration is the ethanol 900 ~ 1100ml of 95%, Borneolum Syntheticum 2 ~ 4g, chlorhexidine acetate 2 ~ 3g.
Further, in every 1000ml finished product, the raw material that effective ingredient comprises following weight is made: Fructus Xanthii 100g, Fructus Tribuli 100g, Flos Caryophylli 20g, Fructus Cnidii 100g, Fructus Zanthoxyli 6g, Chinese honey locust (fruit) 50g, Rhizoma Polygonati 100g, Rhizoma Coptidis 30g, Herba Houttuyniae 60g, Rhizoma Smilacis Glabrae 90g, Radix Achyranthis 100g, Pericarpium Granati 80g.
The invention also discloses above-mentioned a kind of preparation method of product for the treatment of dermatitis, eczema, the method comprises as follows: take following solid material: Fructus Xanthii, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit), Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati, and mix; Measure ethanol, and above-mentioned mixed solid material is added in described ethanol, soak 5 ~ 9 days, after filtration, obtain supernatant.
Further, take following raw material: Borneolum Syntheticum and chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, lysate is joined in above-mentioned supernatant, stirs, get product.
Further, this solid material add volumetric concentration be in the ethanol of 95% before, adopt destructor above-mentioned solid material is ground into powdery.
Further, when soaking, every 4 ~ 6h, described solid material is stirred once.
Further, also comprise finished product to divide and be filled in spray bottle.
In a kind of product for the treatment of skin pruritus of the present invention and preparation method thereof, the raw material of employing has following characteristic:
Fructus Xanthii: record in Shennong's Herbal and cure mainly the solid numbness of rheumatism, wind-repellent itching-relieving, record in " Japan hanako materia medica " and control scrofula, Jie tinea and pruritus.
Fructus Tribuli records wet dissipation removing blood stasis in " book on Chinese herbal medicine is new again ", eliminating carbuncle cellulitis, sore-toxin dispersing, records Fructus Tribuli in " prescriptions worth thousand gold " and controls urine skin ulcer, ripely smashes puncturevine caltrop leaf, with water and painting.
Flos Caryophylli: record treatment edema due to wind pathogen poison swollen in " Mingyi Bielu ", remove bad odor, treat cholera pained.Rhizoma Smilacis Glabrae records treatment malignant boil in Compendium of Material Medica, the effect of carbuncle, record and grind as smalls with this product, and vinegar dresses in " the southern regions of the Yunnan Province book on Chinese herbal medicine ", and treatment carbuncle skin ulcer redness is festered, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Fructus Cnidii: in " Chinese medicine voluminous dictionary ", record that dampness is dispeled the wind, killing parasites for relieving itching, for eczema pruritus.
Fructus Zanthoxyli: record warming middle-JIAO to relieve pain, killing parasites for relieving itching in " middle pharmacopeia ", external treatment eczema, pudendal pruritus.
Chinese honey locust (fruit): record mass dissipating and swelling eliminating in " Chinese medicine voluminous dictionary ", external treatment carbuncle.
Rhizoma Polygonati records anti-hypoxia, resisting fatigue, anti-aging effects in " Chinese medicine voluminous dictionary ", can strengthen immunologic function, strengthens metabolism, and modern medicine proves that Rhizoma Polygonati has antioxidation, slow down aging, antiviral, anastalsis.
Rhizoma Coptidis: record removing toxic substances, parasite killing in " Chinese medicine voluminous dictionary ", row pyretic toxicity when controlling, typhoid fever, for skin sore, eczema, the burning hot wound of soup.In the Pharmacopoeia of the People's Republic of China, record heat clearing and damp drying, external treatment eczema, eczema, auditory meatus is suppurated, carbuncle furuncle.
Herba Houttuyniae: record heat-clearing and toxic substances removing in " property of medicine opinion ", eliminating carbuncle evacuation of pus, controls the diseases such as carbuncle sore.It is swollen that Flos Caryophylli records treatment edema due to wind pathogen poison in " Mingyi Bielu ", removes bad odor, treat cholera pained.
Rhizoma Smilacis Glabrae: record treatment malignant boil in Compendium of Material Medica, the effect of carbuncle, records and grind as smalls with this product, and vinegar dresses in " the southern regions of the Yunnan Province book on Chinese herbal medicine ", and treatment carbuncle skin ulcer redness is festered, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Radix Achyranthis: record blood circulation promoting and blood stasis dispelling in " detailed outline is picked up any lost article from the road ", control traumatic injury, tetanus, kindly again can manage skin ulcer, and record the sterilization that purifies the blood in " south of the Five Ridges gather medicinal herbs record ", fall apart blood and relieving pain, manages beriberi.
Pericarpium Granati: record anthelmintic at the Pharmacopoeia of the People's Republic of China, antidiarrheal, the effect of hemostasis, controls Jie tinea.Record in " book on Chinese herbal medicine asks former " and wash speckle, the effect of mange." Shandong Chinese herbal medicine handbook " two Pericarpium Granatis (parch to black), grind to the powder, with Oleum Sesami furnishing pasty state.Medicine oil shakes up by the used time, dips in the even painting affected part of medicine, semimonthly, control psoriasis with brush pen.
The present invention is a kind of treat dermatitis, eczema the beneficial effect of product and preparation method thereof as follows: 1. therapeutic effect is good, has no side effect.2. skin can not produce dependency, and has protective effect to skin.3. raw material is easy to get, and cost is low.4. preparation method is simple.
Detailed description of the invention
Embodiment 1
Treat a product for dermatitis, eczema, in every 1000ml finished product, the solid material that effective ingredient comprises following weight is made: Fructus Xanthii 90g, Fructus Tribuli 80g, Flos Caryophylli 15g, Fructus Cnidii 90g, Fructus Zanthoxyli 4g, Chinese honey locust (fruit) 40g, Rhizoma Polygonati 90g, Rhizoma Coptidis 25g, Herba Houttuyniae 50g, Rhizoma Smilacis Glabrae 70g, Radix Achyranthis 90g, Pericarpium Granati 70g; Also comprise the ethanol 900ml that volumetric concentration is 95%, Borneolum Syntheticum 2g, chlorhexidine acetate 2g.
The invention discloses above-mentioned a kind of preparation method of product for the treatment of dermatitis, eczema, the method comprises as follows: take following solid material: Fructus Xanthii, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit), Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati; Measure the ethanol that volumetric concentration is 95%, and above-mentioned mixed solid material is ground into powdery, adding volumetric concentration is in the ethanol of 95%, soaks 6 days, is stirred once by solid material every 4h, obtains supernatant after filtration.Take Borneolum Syntheticum and chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, lysate is joined in above-mentioned supernatant, stirs, get product, then finished product is divided and be filled in spray bottle.
Embodiment 2
Treat a product for dermatitis, eczema, the solid material that effective ingredient comprises following weight is made: Fructus Xanthii 100g, Fructus Tribuli 100g, Flos Caryophylli 20g, Fructus Cnidii 100g, Fructus Zanthoxyli 6g, Chinese honey locust (fruit) 50g, Rhizoma Polygonati 100g, Rhizoma Coptidis 30g, Herba Houttuyniae 60g, Rhizoma Smilacis Glabrae 90g, Radix Achyranthis 100g, Pericarpium Granati 80g; Also comprise the ethanol 1000ml that volumetric concentration is 95%, Borneolum Syntheticum 3g, chlorhexidine acetate 25g.
The invention discloses above-mentioned a kind of preparation method of product for the treatment of dermatitis, eczema, the method comprises as follows: take following solid material: Fructus Xanthii, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit) g, Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati; Measure the ethanol that volumetric concentration is 95%, and above-mentioned mixed solid material is ground into powdery, adding volumetric concentration is in the ethanol of 95%, soaks 7 days, is stirred once by solid material every 5h, obtains supernatant after filtration.Take Borneolum Syntheticum and chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, above-mentioned lysate is joined in above-mentioned supernatant, stirs, get product, then finished product is divided and be filled in spray bottle.
Embodiment 3
Treat a product for dermatitis, eczema, in every 1000ml finished product, the solid material that effective ingredient comprises following weight is made: Fructus Xanthii 110g, Fructus Tribuli 100g, Flos Caryophylli 15g, Fructus Cnidii 90g, Fructus Zanthoxyli 3g, Chinese honey locust (fruit) 40g, Rhizoma Polygonati 90g, Rhizoma Coptidis 25g, Herba Houttuyniae 50g, Rhizoma Smilacis Glabrae 70g, Radix Achyranthis 90g, Pericarpium Granati 60g; Also comprise the ethanol 900ml that volumetric concentration is 95%, Borneolum Syntheticum 2g, chlorhexidine acetate 2g.
The invention discloses above-mentioned a kind of preparation method of product for the treatment of dermatitis, eczema, the method comprises as follows: take following solid material: Fructus Xanthii, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit), Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati; Measure the ethanol that volumetric concentration is 95%, and above-mentioned mixed solid material is ground into powdery, adding volumetric concentration is in the ethanol of 95%, soaks 9 days, is stirred once by solid material every 6h, obtains supernatant after filtration.Take Borneolum Syntheticum and chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, above-mentioned lysate is joined in above-mentioned supernatant, stirs, get product, then finished product is divided and be filled in spray bottle.
Embodiment 4
Treat a product for dermatitis, eczema, in every 1000ml finished product, the solid material that effective ingredient comprises following weight is made: Fructus Xanthii 110g, Fructus Tribuli 100g, Flos Caryophylli 30g, Fructus Cnidii 120g, Fructus Zanthoxyli 10g, Chinese honey locust (fruit) 50g, Rhizoma Polygonati 110g, Rhizoma Coptidis 05g, Herba Houttuyniae 60g, Rhizoma Smilacis Glabrae 100g, Radix Achyranthis 110g, Pericarpium Granati 80g; Also comprise the ethanol 1050ml that volumetric concentration is 95%, Borneolum Syntheticum 3g, chlorhexidine acetate 3g.
The invention discloses above-mentioned a kind of preparation method of product for the treatment of dermatitis, eczema, the method comprises as follows: take following solid material: Fructus Xanthii, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit), Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati; Measure the ethanol that volumetric concentration is 95%, and above-mentioned mixed solid material is ground into powdery, adding volumetric concentration is in the ethanol of 95%, soaks 5 days, is stirred once by solid material every 6h, obtains supernatant after filtration.Take lower Borneolum Syntheticum chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, above-mentioned lysate is joined in above-mentioned supernatant, stirs, get product, then finished product is divided and be filled in spray bottle.
Embodiment 5
Treat a product for dermatitis, eczema, in every 1000ml finished product, the solid material that effective ingredient comprises following weight is made: Fructus Xanthii 100g, Fructus Tribuli 110g, Flos Caryophylli 30g, Fructus Cnidii 120g, Fructus Zanthoxyli 10g, Chinese honey locust (fruit) 60g, Rhizoma Polygonati 120g, Rhizoma Coptidis 50g, Herba Houttuyniae 70g, Rhizoma Smilacis Glabrae 100g, Radix Achyranthis 120g, Pericarpium Granati 90g; Also comprise the ethanol 1100ml that volumetric concentration is 95%, Borneolum Syntheticum 4g, chlorhexidine acetate 3g.
The invention discloses above-mentioned a kind of preparation method of product for the treatment of dermatitis, eczema, the method comprises as follows: the solid material taking following weight: the grey ears or side handles of a utensil, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit), Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati; Measure the ethanol that volumetric concentration is 95%, and above-mentioned mixed solid material is ground into powdery, adding volumetric concentration is in the ethanol of 95%, soaks 5 days, is stirred once by solid material every 6h, obtains supernatant after filtration.Take Borneolum Syntheticum and chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, above-mentioned lysate is joined in above-mentioned supernatant, stirs, get product, then finished product is divided and be filled in spray bottle.
In actual use, therapeutic effect of the present invention is good, and patient can not be made to produce dependency, patient A, skin for a long time by the puzzlement of dermatitis, eczema, again and again always.After using the product in this invention, one day 2 ~ 3 times, initial when using 5 days, skin is no longer itched, and then continues again to use, and the skin of dermatitis, eczema recovers completely, effective more, does not leave the sequela of dermatitis, eczema skin.
Claims (8)
1. treat a product for dermatitis, eczema, it is characterized in that, in every 1000ml finished product, the raw material that effective ingredient comprises following weight is made: Fructus Xanthii 90 ~ 110g, Fructus Tribuli 90 ~ 110g, Flos Caryophylli 15 ~ 30g, Fructus Cnidii 90 ~ 120g, Fructus Zanthoxyli 3 ~ 10g, Chinese honey locust (fruit) 40 ~ 60g, Rhizoma Polygonati 90 ~ 120g, Rhizoma Coptidis 25 ~ 50g, Herba Houttuyniae 50 ~ 70g, Rhizoma Smilacis Glabrae 70 ~ 100g, Radix Achyranthis 90 ~ 120g, Pericarpium Granati 60 ~ 90g.
2. according to a kind of product for the treatment of dermatitis, eczema according to claim 1, it is characterized in that, also comprise the raw material of following weight: volumetric concentration is the ethanol 900 ~ 1100ml of 95%, Borneolum Syntheticum 2 ~ 4g, chlorhexidine acetate 2 ~ 3g.
3. according to a kind of product for the treatment of dermatitis, eczema described in claim 1 or 2, it is characterized in that, in every 1000ml finished product, the raw material that effective ingredient comprises following weight is made: Fructus Xanthii 100g, Fructus Tribuli 100g, Flos Caryophylli 20g, Fructus Cnidii 100g, Fructus Zanthoxyli 6g, Chinese honey locust (fruit) 50g, Rhizoma Polygonati 100g, Rhizoma Coptidis 30g, Herba Houttuyniae 60g, Rhizoma Smilacis Glabrae 90g, Radix Achyranthis 100g, Pericarpium Granati 80g.
4. treat the preparation method of product of dermatitis, eczema according to a kind of according to any one of claim 2 ~ 3, it is characterized in that, the method comprises as follows: take following solid material: Fructus Xanthii, Fructus Tribuli, Flos Caryophylli, Fructus Cnidii, Fructus Zanthoxyli, Chinese honey locust (fruit), Rhizoma Polygonati, Rhizoma Coptidis, Herba Houttuyniae, Rhizoma Smilacis Glabrae, Radix Achyranthis, Pericarpium Granati, and mix; Measure ethanol, and above-mentioned mixed solid material is added in described ethanol, soak 5 ~ 9 days, after filtration, obtain supernatant.
5. according to a kind of preparation method of product for the treatment of dermatitis, eczema according to claim 4, it is characterized in that, the method also comprises, take following raw material: Borneolum Syntheticum and chlorhexidine acetate, adopt ethanol Borneolum Syntheticum and chlorhexidine acetate to be dissolved, obtain lysate, described lysate is joined in above-mentioned supernatant, stir, get product.
6. treat the preparation method of product of dermatitis, eczema according to a kind of described in claim 4 or 5, it is characterized in that, described solid material add volumetric concentration be in the ethanol of 95% before, adopt destructor that above-mentioned solid material is ground into powdery.
7. according to a kind of preparation method of product for the treatment of dermatitis, eczema according to claim 6, it is characterized in that, when soaking, every 4 ~ 6h, described solid material being stirred once.
8. according to a kind of preparation method of product for the treatment of dermatitis, eczema according to claim 7, it is characterized in that, also comprise finished product to divide and be filled in spray bottle.
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Cited By (1)
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CN106310063A (en) * | 2016-09-27 | 2017-01-11 | 泰山医学院 | Compound gel for treating eczema and preparation method thereof |
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CN103041173A (en) * | 2012-12-31 | 2013-04-17 | 青岛华仁信息技术开发有限公司 | Traditional Chinese medicine external preparation for curing dermatitis and eczema and preparing method thereof |
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CN103041173A (en) * | 2012-12-31 | 2013-04-17 | 青岛华仁信息技术开发有限公司 | Traditional Chinese medicine external preparation for curing dermatitis and eczema and preparing method thereof |
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CN106310063A (en) * | 2016-09-27 | 2017-01-11 | 泰山医学院 | Compound gel for treating eczema and preparation method thereof |
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