CN101401860A - Externally-applied medicament composition for treating dermatosis - Google Patents
Externally-applied medicament composition for treating dermatosis Download PDFInfo
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- CN101401860A CN101401860A CNA2008102309086A CN200810230908A CN101401860A CN 101401860 A CN101401860 A CN 101401860A CN A2008102309086 A CNA2008102309086 A CN A2008102309086A CN 200810230908 A CN200810230908 A CN 200810230908A CN 101401860 A CN101401860 A CN 101401860A
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Abstract
The invention relates to an external medicament composition for treating skin diseases, which is characterized in that the composition is prepared from the following raw materials in weight portion: 50 to 300 portions of Chinese mugwort leaves, 10 to 60 portions of mint, 10 to 80 portions of dittany bark, 10 to 60 portions of radix salviae miltiorrhizae, 10 to 60 portions of radix scutellariae and 10 to 50 portions of herba schizonepetae. The preparation method adopts the prior traditional Chinese medicine preparation technique, and the external medicament composition can be prepared into external location, liniment, ointment, spraying agent, and the like suitable to be used clinically. In the invention, the traditional Chinese medicine has the efficacies of clearing away heat and expelling the wind, removing dampness to relieve itching, reducing tumescence, and the like, and is suitable for symptoms such as pruritus caused by allergic skin diseases such as hives and the like, and allergic dermatitis, neurodermitis, and the like. Through clinical observation, the external medicament composition has the advantages of short treatment time, quick symptom relieving, good curative effect, safety, no toxic and side effects, and no irritation to skin.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, relate to the dermopathic externally-applied medicinal composition of a kind of treatment specifically.
Background technology
Anaphylaxis dermatosis such as dermatitis, urticaria belongs to the regular incidence frequently-occurring disease and treats than refractory.Urticaria is commonly called as the wind pimple, and its sickness rate is very high, has the people once to do statistics, and about 1/5 people in the whole world suffered from anaphylaxis dermatosis such as urticaria.Owing to influence of various factors, the trend that this disease has sickness rate to increase clinically owing to often influence patient's life, working and learning, causes bigger misery to dermatosis patient in recent years.
Anaphylaxis dermatosis such as western medical treatment dermatitis, urticaria are except oral antihistamines at present, and external used medicine is often based on the corticosteroids preparation.Though clinical use has certain curative effect, pachylosis, atrophy take place in life-time service easily, corticosteroid dermatitis, multiple side effect such as knock-on.Inquiring into new effective medicine is the problem of seeking now, develops a kind of not only safe and reliable but also dermopathic medicine of treatment easily and effectively, also is pharmacy worker's effort target always.
Chinese medicine is low with its toxic and side effects, can prolonged and repeated use and have overwhelming superiority.
Summary of the invention
The Chinese medicine for external application that purpose of the present invention provides a kind of instant effect, short treating period, stable performance, has no side effect for the patient just---be a kind of dermopathic externally-applied medicinal composition that is used for the treatment of, for clinical and patient provide a kind of new selection.
Purpose of the present invention can realize by following technique measures:
The dermopathic externally-applied medicinal composition of treatment of the present invention is that the crude drug by the following weight ratio is prepared from, wherein: Folium Artemisiae Argyi 50-300, Herba Menthae 10-60, Cortex Dictamni 10-80, Radix Salviae Miltiorrhizae 10-60, Radix Scutellariae 10-60, Herba Schizonepetae 10-50.
The preferred prescription of pharmaceutical composition of the present invention is that the crude drug by the following weight ratio is prepared from, wherein: Folium Artemisiae Argyi 100-260, Herba Menthae 15-40, Cortex Dictamni 15-60, Radix Salviae Miltiorrhizae 15-50, Radix Scutellariae 15-40, Herba Schizonepetae 15-35.
The most preferably prescription of pharmaceutical composition of the present invention is that the crude drug by the following weight ratio is prepared from: wherein: Folium Artemisiae Argyi 200, Herba Menthae 20-30, Cortex Dictamni 20-30, Radix Salviae Miltiorrhizae 20-30, Radix Scutellariae 20-30, Herba Schizonepetae 20.
Aforementioned pharmaceutical compositions of the present invention can be prepared into any dosage form that is suitable for using clinically according to conventional process of Chinese medicine preparation preparation, and preferred for preparation becomes external-use lotion, liniment, tincture, ointment, spray etc.
Pharmaceutical composition of the present invention can add conventional excipient, for example: penetrating agent, paste substrate, solvent, antiseptic etc. in being prepared into the process of medicament.
Its preparation method can adopt following step to realize: get above-mentioned raw materials by weight, water or aquiferous ethanol extract in the lump, and the solution concentration of extraction obtains Chinese medicine extract to an amount of.This extract can directly be made preparation, as tincture, or adds the water mixing, leaves standstill, and gets supernatant, and the agent of adding antiseptic is an amount of, adds water to the preparation full dose, gets external-use lotion or liniment.Or be mixed and made into preparation with the medicine acceptable carrier, as above-mentioned Chinese medicine extract can with mixing acceptable accessories, be prepared into various external preparation commonly used, as ointment, spray etc.
The present invention utilizes Folium Artemisiae Argyi regulate the flow of vital energy blood, removing dampness to relieve itching effect, be equipped with the Cortex Dictamni heat clearing and damp drying, the effect of the detoxifcation of dispeling the wind, is controlled the swollen sore of damp and hot pain at Radix Scutellariae clearing up internal heat by using drugs of bitter in taste and cold in nature dampness, assistant is with the Radix Salviae Miltiorrhizae promoting blood circulation to remove blood stasis, sedation-analgesia, the Herba Schizonepetae diffusing wind that induces sweat, rash, the hot wind-heat dissipating of Herba Menthae, treatment skin wind heat rubella etc., each herbal medicine is auxilliary mutually to be effects such as usefulness, performance are dispeled the wind, antipruritic, antiinflammatory, analgesia, play prove effective rapidly, the effect of reinforced effects.
Folium Artemisiae Argyi is the dried leaves of feverfew Chinese mugwort.Have the blood of regulating the flow of vital energy, by cold-damp, the effect of warming the meridian is slept peacefully in hemostasis; External treatment is fried in shallow oil the soup washout can control eczema scabies, removing dampness to relieve itching, skin pruritus etc.In addition, Folium Artemisiae Argyi is to folliculitis, and eczema has certain curative effect.
Cortex Dictamni is the dry root bark of rutaceae shaggy-fruited dittany.Bitter, cold, heat clearing and damp drying, the detoxifcation of dispeling the wind.Be used for damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, rheumatism pyretic arthralgia, jaundice dark coloured urine.
Herba Menthae is the dry aerial parts of labiate Herba Menthae.Have special fragrance, pungent sense and cool sense, dispelling wind-heat, the refresh oneself, rash has diaphoresis, the wind heat of loosing and effect such as antipruritic, is used for measles without adequate eruption, the rubella pruritus.This product light weight a surname loose, and dispelling wind and heat pathogens is arranged, and declares the merit of malicious rash.
Radix Salviae Miltiorrhizae is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.Bitter, be slightly cold, stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for the costa sternales hypochondriac pain, rheumatic arthralgia, the lump in the abdomen caking, skin infection swells and ache, the tumbling down pain of injury etc.
Radix Scutellariae is the dry root of labiate Radix Scutellariae.Feeble QI, bitter in the mouth, heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus etc.
Herba Schizonepetae is the dry aerial parts of labiate Herba Schizonepetae.Gas fragrance, little puckery and hot cold of distinguishing the flavor of, the diffusing wind that induces sweat, rash.Be used for flu, headache, measles, rubella, skin infection from the beginning of and measles without adequate eruption, rubella pruritus etc.
Beneficial effect of the present invention is as follows:
Medicine of the present invention proves through clinical use: has effects such as clearing away heat and expelling wind, removing damp to relieve itching, detumescence, is applicable to the skin pruritus that anaphylaxis dermatosis such as urticaria cause, and disease such as allergic dermatitis, neurodermatitis.Compared with the prior art, the present invention also has the treatment time weak point, and relief of symptoms is fast, and good effect, and safe without toxic side effect are to the skin nonirritant.
The specific embodiment
The present invention is further described below with reference to embodiment, but this should be interpreted as the following example that only limits to of the present invention.All technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1:
Present embodiment adopts following proportioning and processing step to realize:
Get Folium Artemisiae Argyi 200g by weight, Herba Menthae 30g, Cortex Dictamni 30g, Radix Salviae Miltiorrhizae 20g, Radix Scutellariae 20g, Herba Schizonepetae 20g decoct with water twice, each 30 minutes, collecting decoction filters, and adding preservative agent is an amount of, adjust volume to 1000ml with solvent at last, packing promptly gets Chinese medicine lotion.
Embodiment 2:
Present embodiment adopts following proportioning and processing step to realize:
Get Folium Artemisiae Argyi 220g by weight, Herba Menthae 25g, Cortex Dictamni 30g, Radix Salviae Miltiorrhizae 25g, Radix Scutellariae 20g, Herba Schizonepetae 15g, pulverize separately becomes coarse powder, according to the percolation under fluid extract and the extractum item (Chinese Pharmacopoeia version appendix in 2005 IQ), with containing the alcohol amount is that 80% ethanol is made solvent, flood after 48 hours slowly percolation, it is an amount of to collect percolate, is that 80% second alcohol and water is adjusted to 1000ml to contain the alcohol amount, make that to contain alcohol amount be 70%～75%, filter, packing promptly gets tincture.
Embodiment 3:
Present embodiment adopts following proportioning and processing step to realize:
Get Folium Artemisiae Argyi 185g by weight, Herba Menthae 35g, Cortex Dictamni 45g, Radix Salviae Miltiorrhizae 15g, Radix Scutellariae 15g, Herba Schizonepetae 30g, pulverize separately becomes coarse powder, is that 80% ethanol is made solvent with containing the alcohol amount, reflux, extract, is inferior, and each 1 hour, merge extractive liquid, was adjusted to 1000ml, filter, packing promptly gets Chinese medicinal liniment.
Embodiment 4:
Present embodiment adopts following proportioning and processing step to realize:
Get Folium Artemisiae Argyi 250g by weight, Herba Menthae 20g, Cortex Dictamni 40g, Radix Salviae Miltiorrhizae 20g, Radix Scutellariae 30g, Herba Schizonepetae 20g decoct with water twice, each 30 minutes, collecting decoction filters, and is evaporated to the extractum shape, adds antiseptic 0.1% (percentage by weight), stir, packing promptly gets Chinese medicine ointment.
Claims (3)
1. dermopathic externally-applied medicinal composition of treatment, it is characterized in that: this medicine is that the crude drug by the following weight ratio is prepared from, wherein: Folium Artemisiae Argyi 50-300, Herba Menthae 10-60, Cortex Dictamni 10-80, Radix Salviae Miltiorrhizae 10-60, Radix Scutellariae 10-60, Herba Schizonepetae 10-50.
2, pharmaceutical composition according to claim 1 is characterized in that: described medicine is that the crude drug by the following weight ratio is prepared from, wherein: Folium Artemisiae Argyi 100-260, Herba Menthae 15-40, Cortex Dictamni 15-60, Radix Salviae Miltiorrhizae 15-50, Radix Scutellariae 15-40, Herba Schizonepetae 15-35.
3, pharmaceutical composition according to claim 2 is characterized in that: described medicine is that the crude drug by the following weight ratio is prepared from: wherein: Folium Artemisiae Argyi 200, Herba Menthae 20-30, Cortex Dictamni 20-30, Radix Salviae Miltiorrhizae 20-30, Radix Scutellariae 20-30, Herba Schizonepetae 20.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102309086A CN101401860A (en) | 2008-11-17 | 2008-11-17 | Externally-applied medicament composition for treating dermatosis |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008102309086A CN101401860A (en) | 2008-11-17 | 2008-11-17 | Externally-applied medicament composition for treating dermatosis |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018797A (en) * | 2010-11-26 | 2011-04-20 | 新时代健康产业（集团）有限公司 | Traditional Chinese medicine composition with allergy soothing effect, preparation and preparation method thereof |
| CN104288309A (en) * | 2014-10-11 | 2015-01-21 | 高旭利 | Traditional Chinese herbal medicine composition for bathing |
| CN104435862A (en) * | 2014-12-19 | 2015-03-25 | 付生国 | Traditional Chinese medicinal ointment for treating neurodermatitis and preparation method of traditional Chinese medicinal ointment |
| CN104474507A (en) * | 2014-11-26 | 2015-04-01 | 李坤 | Medicine for treating urticaria and preparation method of medicine |
| CN104922554A (en) * | 2015-06-01 | 2015-09-23 | 陈永泉 | Traditional Chinese medicine for treating chronic urticaria |
| CN105213556A (en) * | 2015-09-30 | 2016-01-06 | 罗奕珺 | A kind of traditional Chinese medicine liniment for treating pruritus and preparation method thereof |
| CN105343278A (en) * | 2015-12-15 | 2016-02-24 | 李国深 | Traditional Chinese medicine composition for infant itching dispelling |
| CN105535208A (en) * | 2016-03-16 | 2016-05-04 | 烟台市蓝洋之草医药生物科技有限公司 | Traditional Chinese medicine liniment for treating skin itches and preparation method thereof |
| CN113648372A (en) * | 2021-09-10 | 2021-11-16 | 张掖市中医医院 | A topical ointment for treating dermatoses, and its preparation method |
-
2008
- 2008-11-17 CN CNA2008102309086A patent/CN101401860A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018797A (en) * | 2010-11-26 | 2011-04-20 | 新时代健康产业（集团）有限公司 | Traditional Chinese medicine composition with allergy soothing effect, preparation and preparation method thereof |
| CN102018797B (en) * | 2010-11-26 | 2011-12-07 | 新时代健康产业（集团）有限公司 | Traditional Chinese medicine composition with allergy soothing effect, preparation and preparation method thereof |
| CN104288309A (en) * | 2014-10-11 | 2015-01-21 | 高旭利 | Traditional Chinese herbal medicine composition for bathing |
| CN104474507A (en) * | 2014-11-26 | 2015-04-01 | 李坤 | Medicine for treating urticaria and preparation method of medicine |
| CN104435862A (en) * | 2014-12-19 | 2015-03-25 | 付生国 | Traditional Chinese medicinal ointment for treating neurodermatitis and preparation method of traditional Chinese medicinal ointment |
| CN104922554A (en) * | 2015-06-01 | 2015-09-23 | 陈永泉 | Traditional Chinese medicine for treating chronic urticaria |
| CN105213556A (en) * | 2015-09-30 | 2016-01-06 | 罗奕珺 | A kind of traditional Chinese medicine liniment for treating pruritus and preparation method thereof |
| CN105343278A (en) * | 2015-12-15 | 2016-02-24 | 李国深 | Traditional Chinese medicine composition for infant itching dispelling |
| CN105535208A (en) * | 2016-03-16 | 2016-05-04 | 烟台市蓝洋之草医药生物科技有限公司 | Traditional Chinese medicine liniment for treating skin itches and preparation method thereof |
| CN105832864A (en) * | 2016-03-16 | 2016-08-10 | 烟台市蓝洋之草医药生物科技有限公司 | Purpose of traditional Chinese medicine liniment for preparing medicine for treating pruritus |
| CN113648372A (en) * | 2021-09-10 | 2021-11-16 | 张掖市中医医院 | A topical ointment for treating dermatoses, and its preparation method |
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