CN102657731A - Medicament for treating acute eczema - Google Patents
Medicament for treating acute eczema Download PDFInfo
- Publication number
- CN102657731A CN102657731A CN2012100755939A CN201210075593A CN102657731A CN 102657731 A CN102657731 A CN 102657731A CN 2012100755939 A CN2012100755939 A CN 2012100755939A CN 201210075593 A CN201210075593 A CN 201210075593A CN 102657731 A CN102657731 A CN 102657731A
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- CN
- China
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- parts
- medicament
- acute eczema
- cortex
- treating acute
- Prior art date
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Links
- 239000003814 drug Substances 0.000 title claims abstract description 25
- 201000004624 Dermatitis Diseases 0.000 title claims abstract description 17
- 208000010668 atopic eczema Diseases 0.000 title claims abstract description 17
- 230000001154 acute effect Effects 0.000 title claims abstract description 15
- 229940079593 drug Drugs 0.000 claims abstract description 9
- 235000000177 Indigofera tinctoria Nutrition 0.000 claims abstract description 3
- 229940097275 indigo Drugs 0.000 claims abstract description 3
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 claims abstract description 3
- 241000628997 Flos Species 0.000 claims description 5
- 239000002674 ointment Substances 0.000 claims description 5
- 210000000582 semen Anatomy 0.000 claims description 5
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims description 3
- 239000007919 dispersible tablet Substances 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- -1 instant Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003805 Musa ABB Group Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 235000015266 Plantago major Nutrition 0.000 abstract 1
- 240000003705 Senecio vulgaris Species 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 206010040882 skin lesion Diseases 0.000 description 12
- 231100000444 skin lesion Toxicity 0.000 description 12
- 208000003251 Pruritus Diseases 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 6
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 206010015150 Erythema Diseases 0.000 description 2
- 208000010201 Exanthema Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 206010040844 Skin exfoliation Diseases 0.000 description 2
- 241000209149 Zea Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 230000002354 daily effect Effects 0.000 description 2
- 230000035618 desquamation Effects 0.000 description 2
- 231100000321 erythema Toxicity 0.000 description 2
- 201000005884 exanthem Diseases 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 240000004859 Gamochaeta purpurea Species 0.000 description 1
- 230000009285 allergic inflammation Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicament for treating acute eczema which is prepared from the following materials by weight: 3 to 10 parts of belvedere fruit, 10 to 20 parts of amur corktree bark, 10 to 30 parts of argy wormwood leaf, 10 to 30 parts of groundsel, 5 to 15 parts of atractylodes, 5 to 15 parts of densefruit pittany root-bark, 5 to 15 parts of safflower, 10 to 20 parts of plantain seed, 10 to 20 parts of natural indigo and 10 to 20 parts of glaucousback threewingnut root-bark. The clinical application shows that: the medicament for treating acute eczema described in this invention uses natural medicines therein, and has advantages of quick effect, obvious treatment, good tolerability, low cost and no side-effect.
Description
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of medicament of treating acute eczema.
Background technology
Acute eczema (eczema) is a kind ofly to have the pleomorphism erythra and ooze out tendency, accompanies violent pruritus, is prone to the scytitis of outbreak repeatedly.The inflammatory skin of common epidermis that is caused by multiple internal and external factor and high dermis is sick, and it is generally acknowledged with allergy has certain relation.
But the caused a kind of delayed allergy that interacts that the acute eczema pathogeny mainly is inside and outside motivating factor.Its clinical manifestation has symmetry, exudative, pruritus property, pleomorphism and characteristics such as recurrent, contagiousness.Also be a kind of allergic inflammation dermatoses with the erythra multiformity, be symmetrically distributed, violent pruritus shows effect, is prone to develop into the chronic characteristic that is repeatedly.Can betide any position of any age, but recur or aggravate the winter of being everlasting the tendency of oozing out arranged any season, the chronic course of disease is prone to outbreak repeatedly.
At present, the needs for the medicine of treating acute eczema constantly strengthen.
Summary of the invention
The purpose of this invention is to provide a kind of medicament of treating acute eczema.
In order to realize the object of the invention; The present invention provides a kind of medicament of treating acute eczema, and it is to be processed by weight by following bulk drugs: Fructus Kochiae 3-10 part, Cortex Phellodendri 10-20 part, Folium Artemisiae Argyi 10-30 part, Herba Senecionis Scandentis 10-30 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Cortex Dictamni 5-10 part, Flos Carthami 5-15 part, Semen Plantaginis 10-20 part, Indigo Naturalis 10-20 part and Cortex tripterygii hypoglauci radicis 10-20 part.
Preferably, it is to be processed by weight by following bulk drugs: 15 parts of 5 parts of the Fructus Kochiae, 15 parts of Cortex Phellodendris, 20 parts of Folium Artemisiae Argyis, 20 parts of Herba Senecionis Scandentiss, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts of Cortex Dictamni, 10 parts on Flos Carthami, 15 parts of Semen Plantaginiss, 15 parts of Indigo Naturaliss and Cortex tripterygii hypoglauci radiciss.
Preferably, said medicament is tablet, dispersible tablet, instant, ointment or granule.
Use natural drug in the medicament of treatment acute eczema of the present invention, find through clinical practice, have effect rapidly, therapeutic effect obviously, better tolerance, advantage with low cost, without any side effects.
The specific embodiment
Below description through the specific embodiment the present invention is described further; But this is not to be limitation of the present invention; Those skilled in the art are according to basic thought of the present invention; Can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within scope of the present invention.
The preparation of embodiment 1 ointment of the present invention
Get the Fructus Kochiae 50 grams, Cortex Phellodendri 150 grams, Folium Artemisiae Argyi 200 grams, Herba Senecionis Scandentis 200 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Cortex Dictamni 50 grams, Flos Carthami 100 grams, Semen Plantaginis 150 grams, Indigo Naturalis 150 grams and Cortex tripterygii hypoglauci radicis 150 grams; Pulverize, cross 120 mesh sieves, add Oleum sesami 100 gram furnishing pasty states; The disinfection with high pressure steam sterilization promptly gets.
Experimental example
Diagnostic criteria
The diagnostic criteria reference " clinical dermatology " of acute eczema (Zhao distinguishes clinical dermatology [M] .3 version. Nanjing: and Jiangsu science and technology publishing house, 2001:601.) draft: rapid onset, the course of disease is shorter; Skin lesion with erythema, pimple, ooze out, rotten to the corn, knot is silly, desquamation etc. is main; The lighter is little to itch, and weight person's sufferings are violent, is difficult to stand; Be and intermittently win or the paroxysmal outbreak aggravation at night.
Exclusion standard
Be associated with the eczema of severe infections; The serious concurrent disease of suffering from other system; Not by the regulation medication, not timely further consultation person.
Choose patient's 20 examples that meet above diagnostic criteria, wherein, male 10 examples, women 10 examples, age 15-42 year, 32 years old mean age.
Choosing the ointment of preparation among the embodiment 1 treats.Time spent, every place applied 30 grams with the ointment affected part of exterior coating, and every day 3 times, 3 days is 1 course of treatment, the other drug of stopping using during the treatment.
Before and after the treatment patient's symptom, sign are carried out objective scoring.Carry out with reference to " clinical dermatology " 4 grades of point systems: 1. skin lesion degree: comprise erythema, pimple, ooze out, rotten to the corn, knot is silly, desquamation.0 minute: no skin lesion or pigment alteration is only arranged; 1 minute: slight; 2 minutes: moderate; 3 minutes: severe.2. skin lesion area: be the gross area after the area addition everywhere.0 minute: no skin lesion; 1 minute: skin lesion area＜30cm
22 minutes: the skin lesion gross area was at 30～60cm
2Between; 3 minutes: skin lesion area>=60cm
23. the rash symptom of itching: conscious rash is itched.0 minute: asymptomatic; 1 minute: slight, indistinctly feel to itch, do not cause worry; 2 minutes: moderate, often can feel and itch, scratch sometimes, but do not influence daily routines, can stand; 3 minutes: serious, often can feel and itch, often scratch, and influence daily routines and sleep, be impatient at.
Curative effect determinate standard
With reference to " new Chinese medicine clinical research guideline " (Chinese Medicine science and technology publishing house, version in 2002).Recovery from illness: skin lesion and symptom complete obiteration.Produce effects: skin lesion and resolution of symptoms＞70%.Take a turn for the better: skin lesion and resolution of symptoms 50%～70%.Invalid: skin lesion and resolution of symptoms＜50% or do not have that improvement is counter sees expansion.
Through the observation of a course of treatment is arranged, find that whole patients all meet the treatment standard of recovery from illness, and during whole treatment, do not observe tangible untoward reaction.
Claims (3)
1. medicament of treating acute eczema; It is characterized in that it is to be processed by weight by following bulk drugs: Fructus Kochiae 3-10 part, Cortex Phellodendri 10-20 part, Folium Artemisiae Argyi 10-30 part, Herba Senecionis Scandentis 10-30 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Cortex Dictamni 5-10 part, Flos Carthami 5-15 part, Semen Plantaginis 10-20 part, Indigo Naturalis 10-20 part and Cortex tripterygii hypoglauci radicis 10-20 part.
2. the medicament of treatment acute eczema according to claim 1; It is characterized in that it is to be processed by weight by following bulk drugs: 15 parts of 5 parts of the Fructus Kochiae, 15 parts of Cortex Phellodendris, 20 parts of Folium Artemisiae Argyis, 20 parts of Herba Senecionis Scandentiss, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts of Cortex Dictamni, 10 parts on Flos Carthami, 15 parts of Semen Plantaginiss, 15 parts of Indigo Naturaliss and Cortex tripterygii hypoglauci radiciss.
3. the medicament of treatment acute eczema according to claim 1 and 2 is characterized in that, said medicament is tablet, dispersible tablet, instant, ointment or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210075593 CN102657731B (en) | 2012-03-21 | 2012-03-21 | Medicament for treating acute eczema |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210075593 CN102657731B (en) | 2012-03-21 | 2012-03-21 | Medicament for treating acute eczema |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657731A true CN102657731A (en) | 2012-09-12 |
| CN102657731B CN102657731B (en) | 2013-08-07 |
Family
ID=46767399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210075593 Active CN102657731B (en) | 2012-03-21 | 2012-03-21 | Medicament for treating acute eczema |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102657731B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933397A (en) * | 2014-04-22 | 2014-07-23 | 湖州康企药业有限公司 | Medicine for treating eczema |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08283167A (en) * | 1995-04-13 | 1996-10-29 | Harunire Kikaku:Kk | Lotion for skin disease |
| CN1214261A (en) * | 1998-10-21 | 1999-04-21 | 余际康 | Oral medicine for curing dermatosis |
| CN1768841A (en) * | 2005-10-27 | 2006-05-10 | 湖北鼎龙制药有限公司 | Chinese medicinal compound formulation for treating skin disease |
| KR20080101821A (en) * | 2008-08-27 | 2008-11-21 | 김선일 | Cosmetic included to flos |
| CN101804166A (en) * | 2010-05-05 | 2010-08-18 | 余静 | Traditional Chinese medicine composition for treating dermatitis and eczema of infants |
| WO2011126295A2 (en) * | 2010-04-06 | 2011-10-13 | (주)아모레퍼시픽 | Wrapping fermentation method using medicinal leaves, and composition for external skin application using same |
| CN102343055A (en) * | 2011-09-28 | 2012-02-08 | 李军 | Traditional Chinese medicine composition for treating eczema |
-
2012
- 2012-03-21 CN CN 201210075593 patent/CN102657731B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08283167A (en) * | 1995-04-13 | 1996-10-29 | Harunire Kikaku:Kk | Lotion for skin disease |
| CN1214261A (en) * | 1998-10-21 | 1999-04-21 | 余际康 | Oral medicine for curing dermatosis |
| CN1768841A (en) * | 2005-10-27 | 2006-05-10 | 湖北鼎龙制药有限公司 | Chinese medicinal compound formulation for treating skin disease |
| KR20080101821A (en) * | 2008-08-27 | 2008-11-21 | 김선일 | Cosmetic included to flos |
| WO2011126295A2 (en) * | 2010-04-06 | 2011-10-13 | (주)아모레퍼시픽 | Wrapping fermentation method using medicinal leaves, and composition for external skin application using same |
| CN101804166A (en) * | 2010-05-05 | 2010-08-18 | 余静 | Traditional Chinese medicine composition for treating dermatitis and eczema of infants |
| CN102343055A (en) * | 2011-09-28 | 2012-02-08 | 李军 | Traditional Chinese medicine composition for treating eczema |
Non-Patent Citations (1)
| Title |
|---|
| 李元文等: "《皮肤病》", 31 January 2002, 人民卫生出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933397A (en) * | 2014-04-22 | 2014-07-23 | 湖州康企药业有限公司 | Medicine for treating eczema |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102657731B (en) | 2013-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: LIYANG SHANGHUANG HOSPITALS Free format text: FORMER OWNER: LUO LI Effective date: 20131122 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272100 JINING, SHANDONG PROVINCE TO: 213314 CHANGZHOU, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20131122 Address after: 213314, Huang Zhen Town, Liyang, Jiangsu, Changzhou Patentee after: Liyang Huang Zhen Town Health Center Address before: 272100 emergency department, Central People's Hospital, Jining 44, South North Street, Middle District, Shandong, Jining, Shandong Patentee before: Luo Li |