Background technology
Acute eczema (eczema) is a kind ofly to have the pleomorphism erythra and ooze out tendency, accompanies violent pruritus, easily the scytitis of outbreak repeatedly.The common epidermis that is caused by multiple internal and external factor and the inflammatory skin disease of high dermis, it is generally acknowledged with allergy has certain relation.
But the caused a kind of delayed allergy that interacts that the acute eczema pathogeny mainly is inside and outside motivating factor.Its clinical manifestation has symmetry, exudative, pruritus, pleomorphism and characteristics such as recurrent, contagiousness.Also be a kind of allergic inflammation dermatoses with the erythra multiformity, be symmetrically distributed, violent pruritus shows effect, easily develops into the chronic feature that is repeatedly.Can betide any position of any age, but recur or aggravate the winter of being everlasting the tendency of oozing out be arranged any season, the chronic course of disease, easily outbreak repeatedly.
At present, the needs for the medicine for the treatment of acute eczema constantly strengthen.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of acute eczema.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of acute eczema, it is to be made by weight by following bulk drugs: Fructus Kochiae 3-10 part, Cortex Phellodendri 10-20 part, Folium Artemisiae Argyi 10-30 part, Herba Senecionis Scandentis 10-30 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Cortex Dictamni 5-10 part, Flos Carthami 5-15 part, Semen Plantaginis 10-20 part, Indigo Naturalis 10-20 part and Cortex tripterygii hypoglauci radicis 10-20 part.
Preferably, it is to be made by weight by following bulk drugs: 15 parts of 5 parts of the Fructus Kochiae, 15 parts of Cortex Phellodendris, 20 parts of Folium Artemisiae Argyis, 20 parts of Herba Senecionis Scandentiss, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 5 parts of Cortex Dictamni, 10 parts on Flos Carthami, 15 parts of Semen Plantaginiss, 15 parts of Indigo Naturaliss and Cortex tripterygii hypoglauci radiciss.
Preferably, described medicament is tablet, dispersible tablet, instant, ointment or granule.
Use natural drug in the medicament for the treatment of acute eczema of the present invention, find through clinical practice, have effect rapidly, therapeutic effect obviously, better tolerance, advantage with low cost, without any side effects.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 ointment of the present invention
Get the Fructus Kochiae 50 grams, Cortex Phellodendri 150 grams, Folium Artemisiae Argyi 200 grams, Herba Senecionis Scandentis 200 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Cortex Dictamni 50 grams, Flos Carthami 100 grams, Semen Plantaginis 150 grams, Indigo Naturalis 150 grams and Cortex tripterygii hypoglauci radicis 150 grams, pulverize, cross 120 mesh sieves, add Oleum sesami 100 gram furnishing pasty states, the disinfection with high pressure steam sterilization, namely.
Experimental example
Diagnostic criteria
The diagnostic criteria reference " clinical dermatology " of acute eczema (Zhao distinguishes clinical dermatology [M] .3 version. Nanjing: Jiangsu science and technology publishing house, 2001:601.) draft: rapid onset, the course of disease is shorter, skin lesion based on erythema, pimple, ooze out, rotten to the corn, knot is silly, desquamation etc., the lighter is little to itch, and weight person's sufferings are violent, is difficult to stand, be and intermittently win or the paroxysmal outbreak aggravation at night.
Exclusion standard
Be associated with the eczema of severe infections; The serious concurrent disease of suffering from other system; Not medication in accordance with regulations, not timely further consultation person.
Choose patient's 20 examples that meet above diagnostic criteria, wherein, male 10 examples, women 10 examples, age 15-42 year, 32 years old mean age.
Choosing the ointment of preparation among the embodiment 1 treats.Time spent, every place coating 30 restrained with the ointment affected part of exterior coating, and every day 3 times, 3 days is 1 course for the treatment of, the other drug of stopping using during the treatment.
Before and after the treatment patient's symptom, sign are carried out objective scoring.Carry out with reference to " clinical dermatology " 4 grades of point systems: 1. skin lesion degree: comprise erythema, pimple, ooze out, rotten to the corn, knot is silly, desquamation.0 minute: no skin lesion or pigment alteration is only arranged; 1 minute: slight; 2 minutes: moderate; 3 minutes: severe.2. skin lesion area: be the gross area after the area addition everywhere.0 minute: no skin lesion; 1 minute: skin lesion area<30cm
22 minutes: the skin lesion gross area was at 30~60cm
2Between; 3 minutes: skin lesion area 〉=60cm
23. the rash symptom of itching: conscious rash is itched.0 minute: asymptomatic; 1 minute: slight, indistinctly feel to itch, do not cause worry; 2 minutes: moderate, often can feel and itch, scratch sometimes, but do not influence daily routines, can stand; 3 minutes: serious, often can feel and itch, often scratch, and influence daily routines and sleep, be impatient at.
Curative effect determinate standard
With reference to " new Chinese medicine clinical research guideline " (Chinese Medicine science and technology publishing house, version in 2002).Recovery from illness: skin lesion and symptom complete obiteration.Produce effects: skin lesion and resolution of symptoms>70%.Take a turn for the better: skin lesion and resolution of symptoms 50%~70%.Invalid: skin lesion and resolution of symptoms<50% or do not have that improvement is counter sees expansion.
Through the observation of a course for the treatment of is arranged, find that whole patients all meet the treatment standard of recovery from illness, and during whole treatment, do not observe tangible untoward reaction.