CN103721147B - For treating the Chinese medicine composition of chicken coccidiasis - Google Patents
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Landscapes
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Abstract
The invention provides a kind of Chinese medicine composition for treating chicken coccidiasis, its bulk drug includes sweet wormwood, Radix Glycyrrhizae, asafoetide, giant knotweed, dandelion, azedarach, prepared rhizome of rehmannia, sargentodoxa cuneata, purslane, radix bupleuri, Selaginella tamariscina, the seed of cowherb, the Radix Astragali, the bark of official magnolia, Kaempferia galanga, wilsonii, great burdock achene, betel nut, Semen sesami nigrum, mysorethorn root, Litsea pungens and dragon's paw dish.This Chinese medicine composition has and is not likely to produce drug resistance, and toxic and side effect is minimum, has promotion body growth, strengthens immunologic function, improves the advantages such as body resistance against diseases, has significant effect in terms for the treatment of chicken coccidiasis.
Description
Technical field
The present invention relates to technical field of Chinese medicine, particularly relate to a kind of Chinese drug-treated group for treating chicken coccidiasis
Compound.
Background technology
Chicken coccidiasis (avian coccidiosis) is to be parasitized chicken by Eimeria (Eimeria) coccidia
A kind of parasitic protozoa caused in intestinal epithelial cell is sick.Intensive chicken farm is often to break out coccidia
Sick place, its incidence of disease reaches 60%～80%, and the death rate is 20%～40%, is up to 80% time serious.
Sick chicken is the infection sources of this disease, by the feed of sick chicken pollution, drinking-water, apparatus all with the presence of worm's ovum.
It is major transmission path that chicken eats into infectious egg capsule, and fly, muroid are mechanical transmission medium.Chicken is supported
Drag declines, vitamin A, vitamin K deficiency in feed, and it is sick that malnutrition all can induce this.
Suffer from chicken down in spirits, drowsiness, by Mao Songluan, close mesh drop-head, slow-witted vertical hang wing, like crowded one
Rising, crop is spoken in a low voice hydraulically full, diarrhea of having blood in stool, crissum feathers because manure contamination adhesion, happiness drink or go on a hunger strike,
Visual mucous membrane, hat, whisker are pale.Disease spiritedness symptom in latter stage, stupor, bipod turns up, stiff or spasm.
Since the sulfa drugs forties in last century is used for raising chickens production, successively there are 30 multi-medicaments
Put into clinical practice, bring unprecedented development to modern poultry husbandry, it may be said that there is no coccidiostat
Exploitation application, does not just have modern intensive poultry husbandry.But, along with the extensive application of medicine, coccidia resists
Property of medicine problem is increasingly universal and serious, and the generation of multi-drug resistance or cross-resistance substantially reduces medicine
Business service life.A lot of researchs it has proven convenient that Eimeria species almost to all used coccidiostats all
Create drug resistance, thus cause anticoccidial drug shortening service life, preventing and treating failure or poor effect, draw
Play clinical or subclinical chicken coccidiasis, cause the biggest economic loss.Eimeria species has cross resistance,
When coccidia produces drug resistance to certain coccidiostat, also can be to always producing resistance to not in contact with the medicine crossed
The property of medicine, this drug resistance often comes across between the medicine that chemical constitution is similar, the mechanism of action is close.Resistance to
The generation of the property of medicine is the result that in coccidia colony, mutated individual is repeated several times selection, and coccidia is in its life cycle
Later stage carry out generative propagation, form egg capsule, the most therefore drug resistance passes on from generation to generation.
Conventional coccidiostat is a lot, when using coccidiostat, it is necessary to problem of both consideration:
1, effectively controlling global-worm illness, the loss that global-worm illness is caused is down to minimum；2, coccidia is postponed to used anti-
Coccidia drug resistant, extends the service life of medicine.For reaching previous purpose, height to be leaned on
The coccidiostat of effect, and chicken to be made gradually produces certain protective immunity to coccidia, so needing
Reasonably to use coccidiostat.Producing drug resistance for postponing coccidia, preferable way is periodically conversion
Or the coccidiostat that the use in conjunction mechanism of action is different, it is to avoid excessively use any specific anti-ball
Worm medicine.Alternating mode between the selection of coccidiostat, treatment sequence and several program depends on perhaps
Multifactor, such as characteristic, use history, the using effect in past of various different coccidiostats；Coccidia
There is situation and certain medicine occurred the time etc. of drug resistance in sick epidemiology, drug-resistant worm plant.
Western medicine is expensive, and it is big that coccidia is easily generated drug resistance and medicine residual quantity in chicken product to medicine,
Affecting the health of people, and Chinese medicine has and is not likely to produce drug resistance, toxic and side effect is minimum, has promotion body
Growth, strengthens immunologic function, improves the advantages such as body resistance against diseases, therefore, uses Chinese herbal treatment chicken
Global-worm illness increasingly becomes focus of concern, and the present invention is exactly on the basis of theory of traditional Chinese medical science, it is provided that
A kind of Chinese medicine composition for treating chicken coccidiasis, it has Chinese medicine and has and be not likely to produce drug resistance, poison
Side effect is minimum, has promotion body growth, strengthens immunologic function, improves the advantages such as body resistance against diseases.
Summary of the invention
The technical problem to be solved is to provide a kind of Chinese traditional medicine composition for treating chicken coccidiasis
Thing, it has and is not likely to produce drug resistance, and toxic and side effect is minimum, has promotion body growth, strengthens immunity
Function, improves the advantages such as body resistance against diseases, has significant effect in terms for the treatment of chicken coccidiasis.
For solving above-mentioned technical problem, the invention provides a kind of Chinese traditional medicine composition for treating chicken coccidiasis
Thing, its bulk drug includes sweet wormwood, Radix Glycyrrhizae, asafoetide, giant knotweed, dandelion, azedarach, prepared rhizome of rehmannia, big
Blood rattan, purslane, radix bupleuri, Selaginella tamariscina, the seed of cowherb, the Radix Astragali, the bark of official magnolia, Kaempferia galanga, wilsonii, burdock
Son, betel nut, Semen sesami nigrum, mysorethorn root, Litsea pungens and dragon's paw dish.
Wherein, in described Chinese medicine composition, the weight portion of each bulk drug is respectively sweet wormwood 45 weight portion～55
Weight portion, Radix Glycyrrhizae 25 weight portion～35 weight portions, asafoetide 30 weight portion～40 weight portions, giant knotweed 55
Weight portion～65 weight portions, dandelion 45 weight portion～55 weight portions, azedarach 45 weight portion～55
Weight portion, prepared rhizome of rehmannia 25 weight portion～35 weight portions, sargentodoxa cuneata 30 weight portion～40 weight portions, dent
Amaranth 25 weight portion～35 weight portions, radix bupleuri 30 weight portion～40 weight portions, Selaginella tamariscina 25 weight portion～35
Weight portion, the seed of cowherb 20 weight portion～30 weight portions, the Radix Astragali 50 weight portion～60 weight portions, the bark of official magnolia
30 weight portions～40 weight portions, Kaempferia galanga 25 weight portion～35 weight portions, wilsonii 35 weight portion～45
Weight portion, great burdock achene 20 weight portion～30 weight portions, betel nut 25 weight portion～35 weight portions, Semen sesami nigrum
20 weight portions～30 weight portions, mysorethorn root 25 weight portion～35 weight portions, Litsea pungens 35 weight portion～
45 weight portions and dragon's paw dish 45 weight portion～55 weight portions.
Wherein, in described Chinese medicine composition, the weight portion of each bulk drug is respectively sweet wormwood 48 weight portion～52
Weight portion, Radix Glycyrrhizae 28 weight portion～32 weight portions, asafoetide 33 weight portion～37 weight portions, giant knotweed 58
Weight portion～62 weight portions, dandelion 48 weight portion～52 weight portions, azedarach 48 weight portion～52
Weight portion, prepared rhizome of rehmannia 28 weight portion～32 weight portions, sargentodoxa cuneata 33 weight portion～37 weight portions, dent
Amaranth 28 weight portion～32 weight portions, radix bupleuri 33 weight portion～37 weight portions, Selaginella tamariscina 28 weight portion～32
Weight portion, the seed of cowherb 23 weight portion～27 weight portions, the Radix Astragali 53 weight portion～57 weight portions, the bark of official magnolia
33 weight portions～37 weight portions, Kaempferia galanga 28 weight portion～32 weight portions, wilsonii 38 weight portion～42
Weight portion, great burdock achene 23 weight portion～27 weight portions, betel nut 28 weight portion～32 weight portions, Semen sesami nigrum
23 weight portions～27 weight portions, mysorethorn root 28 weight portion～32 weight portions, Litsea pungens 38 weight portion～
42 weight portions and dragon's paw dish 48 weight portion～52 weight portions.
Wherein, in described Chinese medicine composition, the weight portion of each bulk drug is respectively sweet wormwood 50 weight portion, Radix Glycyrrhizae
30 weight portions, asafoetide 35 weight portion, giant knotweed 60 weight portion, dandelion 50 weight portion, azedarach 50
Weight portion, prepared rhizome of rehmannia 30 weight portion, sargentodoxa cuneata 35 weight portion, purslane 30 weight portion, radix bupleuri 35
Weight portion, Selaginella tamariscina 30 weight portion, the seed of cowherb 25 weight portion, the Radix Astragali 55 weight portion, the bark of official magnolia 35 weight
Amount part, Kaempferia galanga 30 weight portion, wilsonii 40 weight portion, great burdock achene 25 weight portion, betel nut 30 weight
Part, Semen sesami nigrum 25 weight portion, mysorethorn root 30 weight portion, Litsea pungens 40 weight portion and dragon's paw dish 50 weight
Amount part.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, particularly as follows:
Above-mentioned raw materials medicine component is mixed by weight, it is thus achieved that mixture, put in reactor, add phase
For mixture quality 3～the water of 5 times, slow fire heating decocts 2～4 hours, and decoction liquor filters, filter residue
Add relative to previously obtained mixture quality 2～the water of 4 times, again slow fire boiling 1～3 hours,
Decoction liquor filters again, is merged by filtered fluid, concentrates and removes water, it is thus achieved that lotion, dry, pulverize, obtain
Obtain Chinese traditional medicine composition composition powders.
Present invention also offers a kind of Chinese traditional medicine composition composition powders for treating chicken coccidiasis, its raw material cartridge bag
Include sweet wormwood, Radix Glycyrrhizae, asafoetide, giant knotweed, dandelion, azedarach, prepared rhizome of rehmannia, sargentodoxa cuneata, purslane,
Radix bupleuri, Selaginella tamariscina, the seed of cowherb, the Radix Astragali, the bark of official magnolia, Kaempferia galanga, wilsonii, great burdock achene, betel nut, black sesame
Fiber crops, mysorethorn root, Litsea pungens and dragon's paw dish；
The preparation method of described Chinese traditional medicine composition composition powders is specially the most mixed for above-mentioned raw materials medicine component
Close, it is thus achieved that mixture, put in reactor, add relative to mixture quality 3～the water of 5 times, slow fire
Heating decocts 2～4 hours, and decoction liquor filters, filter residue add relative to previously obtained mixture quality 2～
The water of 4 times, again slow fire boiling 1～3 hours, decoction liquor filters again, is merged by filtered fluid, concentrates
Remove water, it is thus achieved that lotion, dry, pulverize, it is thus achieved that Chinese traditional medicine composition composition powders.
Wherein, in described Chinese traditional medicine composition composition powders the weight portion of each bulk drug be respectively sweet wormwood 45 weight portion～
55 weight portions, Radix Glycyrrhizae 25 weight portion～35 weight portions, asafoetide 30 weight portion～40 weight portions, giant knotweed
55 weight portions～65 weight portions, dandelion 45 weight portion～55 weight portions, azedarach 45 weight portion～
55 weight portions, prepared rhizome of rehmannia 25 weight portion～35 weight portions, sargentodoxa cuneata 30 weight portion～40 weight portions,
Purslane 25 weight portion～35 weight portions, radix bupleuri 30 weight portion～40 weight portions, Selaginella tamariscina 25 weight portion～
35 weight portions, the seed of cowherb 20 weight portion～30 weight portions, the Radix Astragali 50 weight portion～60 weight portions,
The bark of official magnolia 30 weight portion～40 weight portions, Kaempferia galanga 25 weight portion～35 weight portions, wilsonii 35 weight portion～
45 weight portions, great burdock achene 20 weight portion～30 weight portions, betel nut 25 weight portion～35 weight portions, black
Sesame 20 weight portion～30 weight portions, mysorethorn root 25 weight portion～35 weight portions, Litsea pungens 35 weight
Part～45 weight portions and dragon's paw dish 45 weight portion～55 weight portions.
Present invention also offers a kind of feed, it includes that feed main body and above-mentioned Chinese medicine composition are as feed
Additive, described Chinese medicine composition feed addictive accounts for the 10%～15% of feeding quality.
Beneficial effects of the present invention:
The Chinese medicine composition that the present invention provides has and is not likely to produce drug resistance, and toxic and side effect is minimum, has rush
Enter body growth, strengthen immunologic function, improve the advantages such as body resistance against diseases, in treatment chicken coccidiasis side
Mask has significant effect.
Detailed description of the invention
The invention provides a kind of Chinese medicine composition for treating chicken coccidiasis, its bulk drug include sweet wormwood,
Radix Glycyrrhizae, asafoetide, giant knotweed, dandelion, azedarach, prepared rhizome of rehmannia, sargentodoxa cuneata, purslane, radix bupleuri, volume
Cypress, the seed of cowherb, the Radix Astragali, the bark of official magnolia, Kaempferia galanga, wilsonii, great burdock achene, betel nut, Semen sesami nigrum, mysorethorn
Root, Litsea pungens and dragon's paw dish.
Further preferably, described Chinese medicine composition is only made up of above-mentioned raw materials medicine.
Fang Zhong, evil outside the sterilization of sweet wormwood, azedarach, betel nut, suppression coccidia expulsion, Radix Glycyrrhizae is invigorated the spleen and benefited qi,
Clearing heat and detoxicating, coordinating the drug actions of a prescription, asafoetide, the bark of official magnolia, Kaempferia galanga appetite-stimulating indigestion-relieving, change stagnant disappear long-pending, giant knotweed, Pu Gong
English gut purge eliminating dampness, gets rid of enterogenous endotoxin, and prepared rhizome of rehmannia, sargentodoxa cuneata blood circulation promoting and enriching, purslane cauline leaf has solution
The features such as poison, heat-clearing, detumescence, all have significant inhibitory action, bavin to Escherichia coli, shigella dysenteriae etc.
Recklessly there is anti-infectious function, the increase of the vasopermeability that histamine or serotonin cause, and energy can be suppressed
The inflammatory activity caused after effectively eliminating or alleviating coccidium infection chicken body, Selaginella tamariscina, the seed of cowherb can cool blood
Hemostasis, relieving diarrhea with astringents, can alleviate hemorrhage, the diarrhea caused because of global-worm illness, the Radix Astragali, wilsonii benefit gas
Invigorating the spleen strengthens immunity of organisms, and Fructus Corni tonifies the liver and kidney, enhancing Abwehrkraft des Koepers, great burdock achene dispelling wind and heat from the body,
Clearing heat and detoxicating, Semen sesami nigrum filling liver kidney, benefiting essence-blood, ease constipation is dry, mysorethorn root removing toxicity for detumescence, in Litsea pungens temperature
Promoting the circulation of qi, drying damp and strengthening spleen, dragon's paw dish heat-clearing desinsection.
Each bulk drug pharmacology particularly as follows:
Sweet wormwood: latin name Artemisiae Annuae Herba, bitter, pungent, cold in nature, return liver, gallbladder channel,
Having clear abnormal heat, cool blood is except steaming, except steaming, and effect of preventing malaria, cure mainly summer-heat evil and generate heat, fever due to yin deficiency,
Night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen etc. is demonstrate,proved.
Radix Glycyrrhizae: taste is sweet, property is flat, returns 12 warps, has clearing heat and detoxicating, the mediation property of medicine, the work of expelling phlegm and arresting coughing
With, and can invigorating the spleen and in, relieving spasm to stop pain, be mainly used in weakness of the spleen and the stomach abdominal distension and anorexia, weak；Can be slow
Solve contraction pain in abdomen, relax the strong and toxicity of some drugs, alleviate the medicine secondary work of poison to body
With or to GI stimulation, tonifying Qi can be played neutralize by adding Radix Glycyrrhizae, be in harmonious proportion the effect of each component.
Asafoetide: bitter, pungent, warm in nature, return kidney, stomach warp, have and disappear long-pending, dissipate ruffian, effect of desinsection,
Stagnating for meat, hemostasis abdominal mass, mass in abdomen, abdominal pain due to enterositosis etc. is demonstrate,proved.
Giant knotweed: mildly bitter flavor, cold nature, returns liver, courage, lung channel, has expelling wind and removing dampness, dissipates stasis of blood analgesic therapy, change
Effect of phlegm and relieving cough, cures mainly joint pain, jaundice with damp-heat pathogen, and through closing, lump in the abdomen, coughing with a lot of sputum, extreme misery scalds
Wound, injury from falling down, carbuncle sore tumefacting virus etc. is demonstrate,proved.
Dandelion: taste is sweet, bitter, cold in nature, enters liver, stomach warp, has clearing heat and detoxicating, the carbuncle that disappears dissipating bind, clear
Liver improving eyesight, the effect of inducing diuresis for treating strangurtia, be mainly used in the treatment of sore swollen toxin, especially notable to acute mastitis effect,
The treatment of the symptoms such as the red eye, swell pain that also can be used for liver-fire flaming, additionally, also have the effect of promoting urination and removing dampness,
For controlling the treatment of the illnesss such as jaundice with damp-heat pathogen, difficult urination, urinary system infection contamination.
Azedarach: latin name Meliae Cortex, bitter, cold in nature, return liver, spleen, stomach warp, have and kill
Worm, treats tinea, for cards such as roundworm disease, enterobiasis, abdominal pain due to enterositosis.
Prepared rhizome of rehmannia: taste is sweet, slightly warm in nature, enter liver, kidney channel, there is enriching yin of enriching blood, benefit essence fills out the effect of marrow,
Sallow for the deficiency of blood；Dizziness, palpitaition, insomnia, irregular menstruation, collapses more than；Liver-kidney Yin deficiency, night sweat,
Foot knee pain, soreness and weakness of waist and knees, Hiccough and deaf, the head is dim-sighted；Seminal emission impotence；Infertility；Menstruation is not
Adjust；Metrostaxis；Poliosis；Quench one's thirst；Constipation；Syndrome characterized by dyspnea etc. of suffering from a deficiency of the kidney is demonstrate,proved.
Sargentodoxa cuneata: bitter, property is put down, is returned liver, large intestine channel, have the carbuncle that disappears that relieves internal heat, promoting blood circulation and removing obstruction in channels, dispels the wind
The effect of desinsection, cures mainly acute and chronic appendicitis, arthralgia due to wind-dampness, dysentery characterized by blood in the stool, and blood drenches, irregular menstruation, infantile malnutrition due to digestive disturbances or intestinalparasites
Long-pending, worm pain, injury from falling down etc. is demonstrate,proved.
Purslane: latin name Portulacae herba, taste acid, cold in nature, return large intestine, Liver Channel, have clear
Thermal detoxification, Li Shui dries, and dissipates blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of the cool blood that stops blooding, master
The cards such as controlling dysentery, enteritis, ephritis, postpartum, uterine hemorrhage, had blood in stool, mastitis.
Radix bupleuri: bitter, cold nature, return liver, gallbladder channel, there is evacuation and bring down a fever, rise effect of the easypro liver of sun,
Curing mainly cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, uterus comes off,
Irregular menstruation etc. are demonstrate,proved.
Selaginella tamariscina: taste is pungent, property is put down, is returned liver, the heart channel of Hang-Shaoyin, effect that having invigorates blood circulation stimulates the menstrual flow.For through closing dysmenorrhoea,
Lump in the abdomen lump in the abdomen, injury from falling down, spit blood, uterine bleeding, to have blood in stool, prolapse of the anus etc. is demonstrate,proved.
The seed of cowherb: bitter, property puts down, enters liver, stomach warp, and having invigorates blood circulation stimulates the menstrual flow, and lactogenesis disappears carbuncle, diuresis
Treating stranguria effect, cures mainly blood stasis through closing, dysmenorrhoea, difficult labour；Lack of lactation after delivery, acute mastitis swells and ache；Heat is drenched,
The cards such as blood drenches, urolithiasis.
The Radix Astragali: taste is sweet, warm in nature, returns lung, the spleen channel, has help spleen soil, rises and lift yang-energy, Gu table is only
Sweat, torr sore myogenic etc. acts on, and is mainly used in treating spleen-lung Qi deficiency caused weak anorexia and loose stool, the heart
Throbbing with fear and breathe hard, the visceral organ ptosis of the sinking of qi of middle-jiao, Qi dysfunction in blood control uterine bleeding is had blood in stool, and rushes down prolapse of the anus for a long time；Exterior deficiency
Not solid spontaneous sweating；Insufficiency of vital energy and blood, yang-energy sore on the decline does not rises, purulence becomes not burst, burst the most not
Hold back；And the deficiency of vital energy loses the oedema of fortune, the symptom such as difficult urination.The Radix Astragali mainly has immunological regulation, resists
Virus, protect the liver and protect kidney, remove harmful free radicals and the effect such as anti-oxidant.In the Radix Astragali main disease-resistant
Poison composition is astragalus polyose.The antivirus action of the Radix Astragali is mainly strengthened by polysaccharide component therein
The immunity of body realizes.Astragalus polyose Main Function in vivo is to promote immunocyte
Propagation, enhancing cellular immunity and humoral immune function, and body can be induced to produce some interferon.
The bark of official magnolia: bitter, pungent, warm in nature, return the spleen channel；Stomach warp；Large intestine channel, has promoting the circulation of qi and disappears long-pending；Eliminating dampness
Except full；Effect of relieving asthma, cures mainly stagnation of QI due to dyspepsia；Abdominal distention constipation；Damp retention in middle-jiao, gastral cavity ruffian is vomited and diarrhoea；
Phlegm stops up the circulation of vital energy in the wrong direction；Fullness sensation in chest such as is breathed with cough at the card.
Kaempferia galanga: warm in nature, taste is pungent, returns stomach warp, has in temperature, helps digestion, and effect of pain relieving cures mainly the heart
Abdomen crymodynia, stops dyspepsia, traumatic injury, toothache, and diet does not disappear to wait and demonstrate,proves.
Fructus Corni: taste is sour, puckery, slightly warm in nature, returns liver, kidney channel, has and tonify the liver and kidney, and puckery essence takes off admittedly
Effect.For dizziness tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, under uterine bleeding band, profuse sweating is empty
De-.Interior heat such as is quenched one's thirst at the card.
Wilsonii: latin name Acanthopanacis Senticosi Radix et Rhizoma seu Caulis,
Taste is pungent, bitter, micro-sweet, warm in nature, enters spleen, kidney, the heart channel of Hang-Shaoyin, has and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, dispels the wind
Effect of dehumidifying, for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence is soft, be slow in action, body void is thin and weak,
Traumatic injury, fracture, oedema, tinea pedis, uncontrolled urination such as are itched at the card.
Great burdock achene: taste is pungent is bitter；Cold in nature, return lung, stomach warp, there is dispelling wind and heat from the body, clearing heat and detoxicating promoting eruption,
A surname's lung profit pharynx dissipates swollen effect, cure mainly anemopyretic cold, warm disease from the beginning of；Wind-heat or cough with lung heat, cough up phlegm not
Freely；Abscess of throat；Macula is impermeable；At the measles initial stage, rash goes out not smooth and rubella itch；Sore swollen toxin and Zha
The cheeks etc. are demonstrate,proved.
Betel nut: bitter, pungent, warm in nature, return stomach, large intestine channel, there is desinsection, disappear long-pending, promoting the circulation of qi, Li Shui,
The cards such as effect of preventing malaria, cures mainly abdominal pain due to enterositosis, stagnates and rushes down dysentery, tenesmus, oedema tinea pedis, malaria.
Semen sesami nigrum: taste is sweet, property is put down, is returned liver, kidney, large intestine channel, have filling liver kidney, benefiting essence-blood, ease constipation
Dry effect, for dizzy, Hiccough and deaf, poliosis, post disease alopecia, the dry constipation of intestines etc. is demonstrate,proved.
Mysorethorn root: bitter, pungent, property puts down, has and dispel rheumatism, effect of removing toxicity for detumescence, cures mainly flu
Heating, cough, abscess of throat, toothache, arthralgia due to wind-dampness, hepatitis, dysentery, stranguria, pruitus,
Venomous snake bites etc. are demonstrate,proved.
Litsea pungens: bitter, pungent, warm in nature, there is promoting the circulation of qi in temperature, drying damp and strengthening spleen, effect of removing toxicity for detumescence,
Cure mainly stomach cold stomachache, summer-heat and damp vomit and diarrhoea, eat stagnant glutted, dysmenorrhoea, sore swell and ache wait demonstrate,prove.
Dragon's paw dish: taste is sweet, micro-puckery, cool in nature, there is removing toxic substances, diuresis, effect of expelling parasite, cure mainly rheumatism
Arthritis, urinary tract infections, parasitosis.
The Chinese medicine composition that the present invention provides contains the material killing or suppressing pathogenic microorganism, can directly kill
Dead polypide or suppression polypide, the growth of worm's ovum, simultaneously, moreover it is possible to excitating organism immunity, strengthen leucocyte
Phagocytosis, promote that antibody is formed, on the one hand the Anti-human globulin test of this Chinese medicine composition, is suppression ball
The growth of worm, is on the other hand the immunologic function by regulating body, produces nospecific immunity to strengthen
Body disease-resistant power, thus eliminate pathogen and alleviate its to histiocytic damage, recover the normal of body
Physiological function.
In described Chinese medicine composition the weight portion of each bulk drug be respectively sweet wormwood 45 weight portion～55 weight portions,
Radix Glycyrrhizae 25 weight portion～35 weight portions, asafoetide 30 weight portion～40 weight portions, giant knotweed 55 weight portion～
65 weight portions, dandelion 45 weight portion～55 weight portions, azedarach 45 weight portion～55 weight portions,
Prepared rhizome of rehmannia 25 weight portion～35 weight portions, sargentodoxa cuneata 30 weight portion～40 weight portions, purslane 25 weight
Amount part～35 weight portions, radix bupleuri 30 weight portion～40 weight portions, Selaginella tamariscina 25 weight portion～35 weight portions,
The seed of cowherb 20 weight portion～30 weight portions, the Radix Astragali 50 weight portion～60 weight portions, the bark of official magnolia 30 weight
Part～40 weight portions, Kaempferia galanga 25 weight portion～35 weight portions, wilsonii 35 weight portion～45 weight portions,
Great burdock achene 20 weight portion～30 weight portions, betel nut 25 weight portion～35 weight portions, Semen sesami nigrum 20 weight
Part～30 weight portions, mysorethorn root 25 weight portion～35 weight portions, Litsea pungens 35 weight portion～45 weight
Part and dragon's paw dish 45 weight portion～55 weight portions.
Further preferably, in described Chinese medicine composition, the weight portion of each bulk drug is respectively sweet wormwood 48 weight
Part～52 weight portions, Radix Glycyrrhizae 28 weight portion～32 weight portions, asafoetide 33 weight portion～37 weight portions,
Giant knotweed 58 weight portion～62 weight portions, dandelion 48 weight portion～52 weight portions, azedarach 48 weight
Part～52 weight portions, prepared rhizome of rehmannia 28 weight portion～32 weight portions, sargentodoxa cuneata 33 weight portion～37 weight
Part, purslane 28 weight portion～32 weight portions, radix bupleuri 33 weight portion～37 weight portions, Selaginella tamariscina 28 weight
Amount part～32 weight portions, the seed of cowherb 23 weight portion～27 weight portions, the Radix Astragali 53 weight portion～57 weights
Amount part, the bark of official magnolia 33 weight portion～37 weight portions, Kaempferia galanga 28 weight portion～32 weight portions, wilsonii 38
Weight portion～42 weight portions, great burdock achene 23 weight portion～27 weight portions, betel nut 28 weight portion～32 weights
Amount part, Semen sesami nigrum 23 weight portion～27 weight portions, mysorethorn root 28 weight portion～32 weight portions, Litsea pungens
38 weight portions～42 weight portions and dragon's paw dish 48 weight portion～52 weight portions.
Most preferably, in described Chinese medicine composition, the weight portion of each bulk drug is respectively sweet wormwood 50 weight portion, sweet
Grass 30 weight portions, asafoetide 35 weight portion, giant knotweed 60 weight portion, dandelion 50 weight portion, azedarach
50 weight portions, prepared rhizome of rehmannia 30 weight portion, sargentodoxa cuneata 35 weight portion, purslane 30 weight portion, radix bupleuri
35 weight portions, Selaginella tamariscina 30 weight portion, the seed of cowherb 25 weight portion, the Radix Astragali 55 weight portion, the bark of official magnolia 35
Weight portion, Kaempferia galanga 30 weight portion, wilsonii 40 weight portion, great burdock achene 25 weight portion, betel nut 30 weight
Amount part, Semen sesami nigrum 25 weight portion, mysorethorn root 30 weight portion, Litsea pungens 40 weight portion and dragon's paw dish 50
Weight portion.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, particularly as follows:
Above-mentioned raw materials medicine component is mixed by weight, it is thus achieved that mixture, put in reactor, add phase
For mixture quality 3～the water of 5 times, slow fire heating decocts 2～4 hours, and decoction liquor filters, filter residue
Add relative to previously obtained mixture quality 2～the water of 4 times, again slow fire boiling 1～3 hours,
Decoction liquor filters again, is merged by filtered fluid, concentrates and removes water, it is thus achieved that lotion, dry, pulverize, obtain
Obtain Chinese traditional medicine composition composition powders.
The using method of the above-mentioned Chinese medicine composition of the present invention is at needs by the stirring of this Chinese traditional medicine composition composition powders
In the feed of feeding, the addition of this Chinese traditional medicine composition composition powders is the 10%～15% of feeding quality, enters one
Step is preferably 12%.
Present invention also offers the preparation method of above-mentioned feed, comprising:
The first step, prepares Chinese medicine composition feed addictive according to the method described above；
Second step, the material composition taking above-mentioned feed in proportion is all grouped together, and puts into compound stirring
Machine stirs 150 minutes, puts into after taking-up in ring mode pulverizer and be ground into powder, then take out and put into
In dryer, the aridity controlling dried material is 70%～80%, and baking time is 50～70 points
Clock, puts into after removal and cooling in multiplex mixer and stirs 190 minutes, put into ring mode bulking machine after taking-up
In expanded, control bulking machine temperature between 70 DEG C～80 DEG C, the expanded time is 1～2 hour, control
The aridity of material to be extruded processed is 80%～90%, proceeds to produce in ring mode grit machine after taking-up
Precipitation hard particles feed, then sieves by 40 meshes.
Hereinafter use embodiment to describe embodiments of the present invention in detail, whereby how the present invention is applied
Technological means solves technical problem, and the process that realizes reaching technique effect can fully understand and real according to this
Execute.
Embodiment 1 Chinese traditional medicine composition composition powders 1
By sweet wormwood 50g, Radix Glycyrrhizae 30g, asafoetide 35g, giant knotweed 60g, dandelion 50g, azedarach 50g,
Prepared rhizome of rehmannia 30g, sargentodoxa cuneata 35g, purslane 30g, radix bupleuri 35g, Selaginella tamariscina 30g, seed of cowherb 25g,
Radix Astragali 55g, bark of official magnolia 35g, Kaempferia galanga 30g, wilsonii 40g, great burdock achene 25g, betel nut 30g, Semen sesami nigrum
25g, mysorethorn root 30g, Litsea pungens 40g and dragon's paw dish 50g mixing, it is thus achieved that mixture, put into reactor
In, adding the water of 3.5kg, slow fire heating decocts 3 hours, and decoction liquor filters, and filter residue adds 2.5kg
Water, again slow fire boiling 3 hours, decoction liquor filters again, is merged by filtered fluid, concentrates and removes water,
Obtain lotion, dry, pulverize, it is thus achieved that Chinese traditional medicine composition composition powders 1.
Embodiment 2 Chinese traditional medicine composition composition powders 2
By sweet wormwood 48g, Radix Glycyrrhizae 28g, asafoetide 33g, giant knotweed 58g, dandelion 48g, azedarach 48g,
Prepared rhizome of rehmannia 28g, sargentodoxa cuneata 33g, purslane 28g, radix bupleuri 33g, Selaginella tamariscina 28g, seed of cowherb 23g,
Radix Astragali 53g, bark of official magnolia 33g, Kaempferia galanga 28g, wilsonii 38g, great burdock achene 23g, betel nut 28g, Semen sesami nigrum
23g, mysorethorn root 28g, Litsea pungens 38g and dragon's paw dish 48g mixing, it is thus achieved that mixture, put into reactor
In, adding the water of 3.5kg, slow fire heating decocts 3 hours, and decoction liquor filters, and filter residue adds 2.5kg
Water, again slow fire boiling 3 hours, decoction liquor filters again, is merged by filtered fluid, concentrates and removes water,
Obtain lotion, dry, pulverize, it is thus achieved that Chinese traditional medicine composition composition powders 2.
Embodiment 3 Chinese traditional medicine composition composition powders 3
By sweet wormwood 52g, Radix Glycyrrhizae 32g, asafoetide 37g, giant knotweed 62g, dandelion 52g, azedarach 52g,
Prepared rhizome of rehmannia 32g, sargentodoxa cuneata 37g, purslane 32g, radix bupleuri 37g, Selaginella tamariscina 32g, seed of cowherb 27g,
Radix Astragali 57g, bark of official magnolia 37g, Kaempferia galanga 32g, wilsonii 42g, great burdock achene 27g, betel nut 32g, Semen sesami nigrum
27g, mysorethorn root 32g, Litsea pungens 42g and dragon's paw dish 52g mixing, it is thus achieved that mixture, put into reactor
In, adding the water of 3.5kg, slow fire heating decocts 3 hours, and decoction liquor filters, and filter residue adds 2.5kg
Water, again slow fire boiling 3 hours, decoction liquor filters again, is merged by filtered fluid, concentrates and removes water,
Obtain lotion, dry, pulverize, it is thus achieved that Chinese traditional medicine composition composition powders 1.
Embodiment 4 toxicology test
Acute toxicity testing
Selecting Kunming mouse 20, female half and half, body weight (20+2) g, by Qingdao City animal used as test
The heart provides, and the powder 1 embodiment 1 prepared is dissolved in distilled water, is prepared as the solution of 1g/ml,
Gavage mouse, through preliminary experiment, fail to detect the LD of oral administration50, therefore survey its maximal tolerance dose,
With the administration volume of 2.0ml/10g body weight, gavage 2 times/d, be spaced 6h, to observation post administration 7d, record
Animal dead and toxicity symptom, at the end of experiment, process all animals, dissect, visually observe
Each main organs lesion tissue situation, after gavaging 140g crude drug/kg for 2 times, animal activity, feed water inlet
Not showing any abnormalities, observe 7d animal dead, gross necropsy has no the obvious abnormal of main organs tissue.
Long term toxicity test
Select 40 male SD rats, weight (180 ± 20) g, Qingdao City's Experimental Animal Center carry
Confession, is randomly divided into 2 groups, blank group and Chinese drug-treated group, often group 20, and blank group is distilled
Water, the powder 1 that embodiment 1 is prepared by Chinese drug-treated group is dissolved in distilled water, is prepared as the solution of 1g/ml,
Gavaging rat, the amount of gavaging is 50g crude drug/kg, on every Mondays to gastric infusion in morning Saturday 1 time, continuously
180d, be administered volume be 2mL/100g body weight, be administered before and be administered during every day observe the general shape of rat
State, sign, food ration, drinking-water and ight soil situation.During administration 90d after last is administered 24h, each group
Extract 6, male and female half and half；After during 180d, last is administered 24h, each group extraction 6, male and female half and half；
After drug withdrawal, 30d respectively organizes extraction 6, male and female half and half, anaesthetizes with urethane, takes blood from abdominal aortic,
Each group is all killed and takes animal, checks hematology and blood parameters, after taking blood, amass wealth by heavy taxation at once core, liver,
Kidney, spleen, lung, adrenal gland, thyroid gland, thymus gland, testis, ovary, uterus, brain, prostate etc. are dirty
Device is weighed, according to weight calculator official's weight coefficient and make pathological examination.
On inspection, during successive administration, the activity of animal, body weight, food ration, stool and hair light
Pool degree no abnormality seen, animal has no dead, and naked eyes have no obvious pathology, each group rat peripheral blood picture inspection
Looking into all in normal range (NR), the raw tea index of blood is all in normal range (NR), and Chinese drug-treated group Rats Organs and Tissues coefficient is with blank
Control group is compared and is not significantly different from.
Embodiment 5 zoopery
Experimental agents: diclazuril, Jiangsu animal drug factory produces；Dissipating of the embodiment of the present invention 1 preparation
Agent 1.
Animal used as test: provided 30 age in days health hybrid meat chicken totally 800 by Qingdao City certain body raiser.
It is uninfected by global-worm illness, the most unused any coccidia chemoprophylaxis and treatment after testing.
Test worm strain: E. pubescens Msxim is provided by Qingdao Agricultural University's animal medicine laboratory,
Purebred Eimeria egg capsule liquid for 16.8 ten thousand/ml of egg capsule concentration.
Packet and treatment:
800 chickens are randomly divided into 5 groups, and often group 200, is respectively as follows: the first infection administration group, will
Inoculate 100,000 E. pubescens Msxim, after symptom occurs, gavage the embodiment of the present invention 1 and prepare
Powder 1, be dissolved in water, it is thus achieved that 1g/ml crude drug concentration, gavage for ill chicken, every day fills
Dosing is 50ml；Second infects administration group, will inoculate 100,000 E. pubescens Msxim, and occur
After symptom, every day feeding 1mg/kg diclazuril；Infect and be not administered group, by soft for inoculation 100,000
Tender Eimeria egg capsule, after there is symptom, is not administered；Control group, does not infect egg capsule, without appointing
What drug therapy.
The preparation of egg capsule: take the egg capsule liquid 125ml that concentration is 16.8 ten thousand/ml, with point dilutions such as water
Becoming 2 parts, be placed in CEN-TR IFU GE TDL-5 type centrifuge, 3000r/min is centrifuged 3 times,
10min every time.Abandoning supernatant after centrifugal, takes out lower floor's egg capsule and is made into the homogeneous solution of 210ml,
Egg capsule liquid concentration now is 100,000/ml.
Inoculation egg capsule liquid: chicken syringe gavages 1.0ml egg capsule liquid to (100,000 egg capsules) in crop.
Feeding and management method is raised routinely, the raising situation of timing every day viewing test chicken and incidence
Deng.
Therapeutic evaluation:
Ight soil is scored: with reference to the standard of Morehouse (1970), i.e. 4d after artificial challenge opens
Beginning to observe blood stool situation, score by every chicken, and make group mean, normal fecal stools remembers 0 point,
Every day every, chicken averagely occurred that how many heap ight soil remembers how many points the most respectively.
Lesion score: with reference to the standard of (1970) such as John son, cuts open all test chickens of inspection, according to cuing open inspection
In rear intestinal, the order of severity of pathology is scored, and remembers 0 point without pathology, and Minimal change remembers 1 point, caecum wall
Thicken little to medium hemorrhage note 2 points, inside had a lot of clot to remember 3 points, because coccidium infection death remembers 4
Point.And make group mean.
Pathology value: with reference to the standard of M erck Sharp, the most often organize lesion score average × 10 of chicken.
Egg capsule counts: infecting after egg capsule the 5th, 6, in the ight soil of 7d excretion, each group is divided multiple spot respectively
Selected part bloody stool and fresh normal ight soil 1g typically, weighs 1g after 7d mixes again.
Add 9ml physiological saline, be placed in mortar and be lightly ground, after homogeneous solution to be programmed, take 1ml and add
Saturated saline solution 8ml, is placed in 10ml test tube, then vibration shakes up, and draws appropriate equal with glue head dropper
Even solution topping up is in M cM aster counter, after being full of counting chamber, is placed in XS-212-201 raw
Reason basis of microscopic observation counting.First the first lattice finding the counting chamber upper left corner start counting up, from top to bottom
" S " type counting, counts up to the worm's ovum number in 100 lattice of counting chamber from top to bottom.Worm by 100 lattice
Ovum number is multiplied by 600 and is egg capsule counter value, counts each group of egg sac number the most respectively.
Egg capsule index: egg capsule index=control group or test group egg sac number/infection be not administered group egg sac number ×
100%.
Egg capsule value: the clear standard in reference angle field, when i.e. egg capsule index is less than 1%, egg capsule value is 0；1%～
5 it are designated as when 25%；26%～50% is 10；It is 20 when 51%～75%；76%～100%
Time be 40.
Percentage weight increase: the average weight gain of rate of body weight gain=each infected group/control group group average weight gain ×
100%.
Anticoccidial index (ACI): use the standard of Merck & Co., Inc., it may be assumed that anticoccidial index=(weightening finish percentage
Rate+survival rate)-(pathology value+egg capsule value).ACI≤120 are invalid, during ACI=120～160 is
Deng effective, ACI=160～180 is good, and ACI > 180 is outstanding.
Result:
Death condition after inoculation coccidian oocyst: after inoculation coccidian oocyst, death condition is shown in Table 1.First infects
Administration group, after inoculation egg capsule, 4d starts dead 16, dead 8 of 2d, 3d after medication
Dead 2, dead 26 altogether, second infects administration group 4d after inoculation egg capsule starts dead 19, uses
Dead 7 of 2d after medicine, dead 3 of 3d, dead 29 altogether, the 3rd infects administration group exists
After inoculation egg capsule, 4d starts dead 16, dead 12 of 2d after medication, 3d dead 7
Only, dead 4 of 4d, dead 39 altogether, infect and be not administered group dead 133 altogether, control group is not
Death occurs.
Table 1 is each group chicken death situation after inoculating coccidian oocyst
| Group | Chicken number (only) | Death toll (only) | The death rate (%) |
| First infects administration group | 200 | 16 | 8 |
| Second infects administration group | 200 | 39 | 19.5 |
| Infect and be not administered group | 200 | 133 | 66.5 |
| Control group | 200 | 0 | 0 |
Ight soil is scored: the first infection administration group and second infects administration group 4d chicken after inoculation egg capsule and opens
Beginning bloody stool occur, 5d starts to be administered, and 6d bloody stool significantly reduces, and 5d bloody stool is the most serious,
And infect and be not administered group 6d the most seriously, 7d starts to reduce.The mean score of each group is shown in Table 2.
Anticoccidial index (ACI)
As can be seen from Table 2 first infect administration group relatively infect be not administered group anticoccidial index significantly improve (P
< 0.01), it also significantly improves (P < 0.01) than the second infection administration group anticoccidial index.
Table 2 is each group chicken manure just egg capsule numeration situation after inoculating coccidian oocyst
Lesion score and pathology value: from table 3 it can be seen that first infects administration group and the second infection administration
Group pathology value is not all administered group significantly lower than infecting, and first infects the relatively second infection of administration group pathology value is administered
Organize lower.
Lesion score and the pathology value of each group of chicken tested by table 3
The body weight of table 4 off-test front and rear each test group chicken and Gain weight
All above-mentioned primary implement these intellectual properties, do not set limit other forms enforcement this
Plant new product and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised,
To realize similar implementation status.But, all modifications or transformation belong to reservation based on new product of the present invention
Right.
The above, be only presently preferred embodiments of the present invention, is not that the present invention makees other form
Restriction, any those skilled in the art are changed possibly also with the technology contents of the disclosure above
Or it is modified as the Equivalent embodiments of equivalent variations.But every without departing from technical solution of the present invention content, depend on
Any simple modification, equivalent variations and remodeling above example made according to the technical spirit of the present invention,
Still fall within the protection domain of technical solution of the present invention.
Claims (6)
1. one kind for treating the Chinese medicine composition of chicken coccidiasis, it is characterised in that: bulk drug by sweet wormwood,
Radix Glycyrrhizae, asafoetide, giant knotweed, dandelion, azedarach, prepared rhizome of rehmannia, sargentodoxa cuneata, purslane, radix bupleuri, volume
Cypress, the seed of cowherb, the Radix Astragali, the bark of official magnolia, Kaempferia galanga, wilsonii, great burdock achene, betel nut, Semen sesami nigrum, mysorethorn
Root, Litsea pungens and dragon's paw dish are constituted；
In described Chinese medicine composition the weight portion of each bulk drug be respectively sweet wormwood 45 weight portion～55 weight portions,
Radix Glycyrrhizae 25 weight portion～35 weight portions, asafoetide 30 weight portion～40 weight portions, giant knotweed 55 weight portion～
65 weight portions, dandelion 45 weight portion～55 weight portions, azedarach 45 weight portion～55 weight portions,
Prepared rhizome of rehmannia 25 weight portion～35 weight portions, sargentodoxa cuneata 30 weight portion～40 weight portions, purslane 25 weight
Amount part～35 weight portions, radix bupleuri 30 weight portion～40 weight portions, Selaginella tamariscina 25 weight portion～35 weight portions,
The seed of cowherb 20 weight portion～30 weight portions, the Radix Astragali 50 weight portion～60 weight portions, the bark of official magnolia 30 weight
Part～40 weight portions, Kaempferia galanga 25 weight portion～35 weight portions, wilsonii 35 weight portion～45 weight portions,
Great burdock achene 20 weight portion～30 weight portions, betel nut 25 weight portion～35 weight portions, Semen sesami nigrum 20 weight
Part～30 weight portions, mysorethorn root 25 weight portion～35 weight portions, Litsea pungens 35 weight portion～45 weight
Part and dragon's paw dish 45 weight portion～55 weight portions.
2. Chinese medicine composition as claimed in claim 1, it is characterised in that: each in described Chinese medicine composition
The weight portion of bulk drug is respectively sweet wormwood 48 weight portion～52 weight portions, Radix Glycyrrhizae 28 weight portion～32 weight
Part, asafoetide 33 weight portion～37 weight portions, giant knotweed 58 weight portion～62 weight portions, dandelion 48 weight
Amount part～52 weight portions, azedarach 48 weight portion～52 weight portions, prepared rhizome of rehmannia 28 weight portion～32 weights
Amount part, sargentodoxa cuneata 33 weight portion～37 weight portions, purslane 28 weight portion～32 weight portions, radix bupleuri
33 weight portions～37 weight portions, Selaginella tamariscina 28 weight portion～32 weight portions, the seed of cowherb 23 weight portion～
27 weight portions, the Radix Astragali 53 weight portion～57 weight portions, the bark of official magnolia 33 weight portion～37 weight portions, Kaempferia galanga
28 weight portions～32 weight portions, wilsonii 38 weight portion～42 weight portions, great burdock achene 23 weight portion～
27 weight portions, betel nut 28 weight portion～32 weight portions, Semen sesami nigrum 23 weight portion～27 weight portions, cloud
Real root 28 weight portion～32 weight portions, Litsea pungens 38 weight portion～42 weight portions and dragon's paw dish 48 weight
Part～52 weight portions.
3. Chinese medicine composition as claimed in claim 1 or 2, it is characterised in that: described Chinese medicine composition
In the weight portion of each bulk drug be respectively sweet wormwood 50 weight portion, Radix Glycyrrhizae 30 weight portion, asafoetide 35 weight portion,
Giant knotweed 60 weight portion, dandelion 50 weight portion, azedarach 50 weight portion, prepared rhizome of rehmannia 30 weight portion,
Sargentodoxa cuneata 35 weight portion, purslane 30 weight portion, radix bupleuri 35 weight portion, Selaginella tamariscina 30 weight portion, king
Do not stay row 25 weight portion, the Radix Astragali 55 weight portion, the bark of official magnolia 35 weight portion, Kaempferia galanga 30 weight portion, thorn five
Add 40 weight portions, great burdock achene 25 weight portion, betel nut 30 weight portion, Semen sesami nigrum 25 weight portion, mysorethorn
Root 30 weight portion, Litsea pungens 40 weight portion and dragon's paw dish 50 weight portion.
4. the preparation method of Chinese medicine composition described in claim 1 or 2, it is characterised in that:
Above-mentioned raw materials medicine component is mixed by weight, it is thus achieved that mixture, put in reactor, add phase
For mixture quality 3～the water of 5 times, slow fire heating decocts 2～4 hours, and decoction liquor filters, filter residue
Add relative to previously obtained mixture quality 2～the water of 4 times, again slow fire boiling 1～3 hours,
Decoction liquor filters again, is merged by filtered fluid, concentrates and removes water, it is thus achieved that lotion, dry, pulverize, obtain
Obtain Chinese traditional medicine composition composition powders.
5. the Chinese traditional medicine composition composition powders being used for treating chicken coccidiasis, it is characterised in that: bulk drug is by green grass or young crops
Wormwood artemisia, Radix Glycyrrhizae, asafoetide, giant knotweed, dandelion, azedarach, prepared rhizome of rehmannia, sargentodoxa cuneata, purslane, radix bupleuri,
Selaginella tamariscina, the seed of cowherb, the Radix Astragali, the bark of official magnolia, Kaempferia galanga, wilsonii, great burdock achene, betel nut, Semen sesami nigrum, cloud
Real root, Litsea pungens and dragon's paw dish are constituted；
In described Chinese traditional medicine composition composition powders, the weight portion of each bulk drug is respectively sweet wormwood 45 weight portion～55 weights
Amount part, Radix Glycyrrhizae 25 weight portion～35 weight portions, asafoetide 30 weight portion～40 weight portions, giant knotweed 55 weight
Amount part～65 weight portions, dandelion 45 weight portion～55 weight portions, azedarach 45 weight portion～55 weights
Amount part, prepared rhizome of rehmannia 25 weight portion～35 weight portions, sargentodoxa cuneata 30 weight portion～40 weight portions, purslane
25 weight portions～35 weight portions, radix bupleuri 30 weight portion～40 weight portions, Selaginella tamariscina 25 weight portion～35 weights
Amount part, the seed of cowherb 20 weight portion～30 weight portions, the Radix Astragali 50 weight portion～60 weight portions, the bark of official magnolia
30 weight portions～40 weight portions, Kaempferia galanga 25 weight portion～35 weight portions, wilsonii 35 weight portion～45
Weight portion, great burdock achene 20 weight portion～30 weight portions, betel nut 25 weight portion～35 weight portions, Semen sesami nigrum
20 weight portions～30 weight portions, mysorethorn root 25 weight portion～35 weight portions, Litsea pungens 35 weight portion～
45 weight portions and dragon's paw dish 45 weight portion～55 weight portions；
The preparation method of described Chinese traditional medicine composition composition powders is specially the most mixed for above-mentioned raw materials medicine component
Close, it is thus achieved that mixture, put in reactor, add relative to mixture quality 3～the water of 5 times, slow fire
Heating decocts 2～4 hours, and decoction liquor filters, filter residue add relative to previously obtained mixture quality 2～
The water of 4 times, again slow fire boiling 1～3 hours, decoction liquor filters again, is merged by filtered fluid, concentrates
Remove water, it is thus achieved that lotion, dry, pulverize, it is thus achieved that Chinese traditional medicine composition composition powders.
6. a feed, it is characterised in that: include feed main body and the claim as feed addictive
Chinese medicine composition described in 1 or 2, described Chinese medicine composition feed addictive account for feeding quality 10%～
15%.
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| CN103251858A (en) * | 2013-05-13 | 2013-08-21 | 安徽农业大学 | Traditional Chinese medicine composite for resisting parasite of free-ranging chicken and preparation method thereof |
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| CN103251858A (en) * | 2013-05-13 | 2013-08-21 | 安徽农业大学 | Traditional Chinese medicine composite for resisting parasite of free-ranging chicken and preparation method thereof |
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Effective date of registration: 20170504 Address after: 257499 Shandong city of Dongying province Lijin Economic Development Zone Patentee after: SHANDONG XINHE BIOLOGICAL PHARMACEUTICAL Co.,Ltd. Address before: Qingdao City, Shandong province 266033 Taiwan Liu Road No. 138 B Patentee before: Yang Gaolin |
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Denomination of invention: Traditional Chinese medicine composition for treating chicken coccidiosis Effective date of registration: 20210617 Granted publication date: 20160817 Pledgee: Dongying Lijin sub branch of Bank of Qilu Co.,Ltd. Pledgor: SHANDONG XINHE BIOLOGICAL PHARMACEUTICAL Co.,Ltd. Registration number: Y2021980004833 |
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Date of cancellation: 20220624 Granted publication date: 20160817 Pledgee: Dongying Lijin sub branch of Bank of Qilu Co.,Ltd. Pledgor: SHANDONG XINHE BIOLOGICAL PHARMACEUTICAL Co.,Ltd. Registration number: Y2021980004833 |
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Denomination of invention: Traditional Chinese medicine composition for treating chicken Coccidiosis Effective date of registration: 20230609 Granted publication date: 20160817 Pledgee: Dongying Lijin sub branch of Bank of Qilu Co.,Ltd. Pledgor: SHANDONG XINHE BIOLOGICAL PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980043309 |
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Granted publication date: 20160817 Pledgee: Dongying Lijin sub branch of Bank of Qilu Co.,Ltd. Pledgor: SHANDONG XINHE BIOLOGICAL PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980043309 |
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