CN103720752A - External preparation used for promoting hair growth and nourishing hair, and preparation method thereof - Google Patents
External preparation used for promoting hair growth and nourishing hair, and preparation method thereof Download PDFInfo
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- CN103720752A CN103720752A CN201210387061.9A CN201210387061A CN103720752A CN 103720752 A CN103720752 A CN 103720752A CN 201210387061 A CN201210387061 A CN 201210387061A CN 103720752 A CN103720752 A CN 103720752A
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Abstract
The invention belongs to the field of medicine, and especially relates to an external preparation used for promoting hair growth and nourishing hair, and a preparation method thereof. 1000 parts of the external preparation comprise following ingredients, by weight, 1 to 7 parts of ginsenoside, 4 o 7 parts of cathe rine genistein, 40 to 60 parts of minoxidil, 1 to 7 parts of allantoin, 6 to 12 parts of menthol, 10 to 30 parts of azone, 200 to 350 parts of propylene glycol, 1 to 15 parts of phytosterol, 80 to 120 parts of purified water, and the balance ethyl alcohol. Beneficial effects of the external preparation are that: the external preparation is prepared via combination of traditional Chinese medicines with Western medicines; and phytosterol is added. The most significant function of phytosterol is 'intelligent management' parahormone function; phytosterol possesses a certain degree of hormone activity in body, but no hormone side effect is caused; when the hormone level of human body is higher than a normal value, phytosterol is capable of preventing bile hormone absorption, and reducing the hormone level of human body.
Description
Technical field
The present invention relates to drug world, relate in particular to a kind of hair growth promoting and hair care external preparation and preparation method thereof.
Background technology
Medicine and the cosmeceutical of hair growth are many at present, although better to alopecia areata effect, yet poor to androgenetic alopecia effect, the general correct hair quality amount of people is more and more paid attention to.
Androgenetic alopecia is modal alopecia, and former title seborrheic alopecia thinks that in scalp tissue structure, sebum secretion is hyperfunction, causes the oily matter of secretion too much, has changed the organizational structure of normal scalp.The surely real androgenetic alopecia of Recent study is to be autosome dominant disease, Hyperandrogenism or androgen sensitivity is occupied to critical role in morbidity, and its inherited character need just show under androgenic effect.Skin has androgenic target cell, scalp has 5α-reductase, it can make testosterone be converted into dihydrotestosterone, the two be positioned at the hair follicle of scalp, the androgen receptor of sebaceous gland in conjunction with forming complex, enter nucleus, be attached on the special estrogen responsive element of gene loci, thus the cell internal procedure of mediation hair growth.This process acts on the hair tissue of hereditary basis individuality, shows as mao trophophase and shortens, and resting stage hair increases relatively, and repeated action result causes hair follicle and dwindles, and terminal hair reverses to fine hair on birds or animals hair, and this kind of phenomenon is gradual with age.Morbidity can early start from teenager, and evening, patient's showed increased and be tending towards younger, was common alopecia to person in middle and old age.In the epoch of particularly day by day improving when people's living standard, to hair, beauty treatment requires to strengthen, and control androgenetic alopecia has become hot issue, become the beauty treatment of people's hair in the urgent need to, therefore research and development control androgenetic alopecia acquires a special sense.
Hair growth agent in the market has 2% or 5% minoxidil in minoxidil tincture, is pure Western medicine preparation, and alopecia areata and androgenetic alopecia are had to certain effect, is medicine for external use conventional on market, also has Radix Ginseng hair growth promoting tincture and other Chinese medicine for outer use, and alopecia is also had to certain effect.
But the therapeutic effect of above medicament is subject to certain restrictions.
Summary of the invention
The object of invention: for a kind of effective medicine that can effectively treat alopecia areata, androgenetic alopecia and other alopecias is provided, this medicine also can do hair growth promoting and hair care medicine is used.
In order to reach as above object, the present invention takes following technical scheme:
Scheme 1:
Hair growth promoting and a hair care external preparation, is characterized in that, 1～7 part of the material ginsenoside (Ginsenoside) who comprises following weight fraction; Soybean isoflavone (Cathe Rine Genistein) 4～7; Minoxidil (Minoxidil) 40-60 part; 1～7 part of allantoin (Allantoin); 6～12 parts of Mentholums (Menthol); 10～30 parts of azones; 200～350 parts of propylene glycol (Propylene Glycol); 1～15 part of plant sterol; 80～120 parts of purified water; Ethanol adds to 1000 parts.
The further technical scheme of the present invention is, 3 parts of the material ginsenosides (Ginsenoside) who comprises following weight fraction; 5 parts of soybean isoflavone (Cathe Rine Genistein); 50 parts of minoxidils (Minoxidil); 3 parts of allantoin (Allantoin); 10 parts of Mentholums (Menthol); 20 parts of azones; 300 parts of propylene glycol (Propylene Glycol); 7 parts of plant sterols; 100 parts of purified water; Ethanol adds to 1000 parts.
Scheme 2:
Preparation is arbitrarily described a kind of hair growth promoting and the method for hair care external preparation as above, it is characterized in that, the as above material of ratio is mixed.
Adopt as above the present invention of technical scheme, there is following beneficial effect: Chinese medicine and western medicine combination, the one, the extract of Chinese medicine, the ginsenoside who extracts from Chinese's ginseng, the soybean isoflavone extracting from Semen sojae atricolor in addition; The 2nd, our times is generally acknowledged the minoxidil that has sure hair regrowth; The 3rd, add penetration enhancers, wetting agent, promote drug absorption, improve the function of hair follicle; Most important, added plant sterol.Through physical purification, to obtain from Semen Maydis, Semen sojae atricolor, maximum function is exactly the parahormone function of " intelligent management ", it can show certain hormonal activity in vivo, but the side effect without hormone, when human hormone's level is during higher than normal value, plant sterol meeting " work ", represent the effect that it hinders gallbladder hormone to absorb, reduce human hormone's level, when human hormone's level is during lower than normal value, plant sterol meeting " conversion " becomes all hormones of human body, improves human hormone's level, thereby reaches balance.Plant sterol has very high permeability to skin, can keep skin surface moisture content, promotes skin metabolism, suppresses scytitis, can anti-sunburn, skin aging, also have the effect of hair growth promoting, hair care.Regulate human body hormonal readiness, aspect anti-ageing waiting for a long time, having special-effect.
The specific embodiment
Embodiment 1
1 part of ginsenoside (Ginsenoside); Soybean isoflavone (Cathe Rine Genistein) part; 40 parts of minoxidils (Minoxidil); 7 parts of allantoin (Allantoin); 6 parts of Mentholums (Menthol); 10 parts of azones; 200 parts of propylene glycol (Propylene Glycol); 1 part of plant sterol; 80 parts of purified water; Ethanol adds to 1000 parts.
Each material mix homogeneously is obtained to medicine.
Embodiment 2
7 parts of ginsenosides (Ginsenoside); 4 parts of soybean isoflavone (Cathe Rine Genistein); 60 parts of minoxidils (Minoxidil); 1 part of allantoin (Allantoin); 12 parts of Mentholums (Menthol); 30 parts of azones; 350 parts of propylene glycol (Propylene Glycol); 15 parts of plant sterols; 120 parts of purified water; Ethanol adds to 1000 parts.
Each material mix homogeneously is obtained to medicine.
Embodiment 3 (being optimum embodiment)
3 parts of the material ginsenosides (Ginsenoside) who comprises following weight fraction; 5 parts of soybean isoflavone (Cathe Rine Genistein); 50 parts of minoxidils (Minoxidil); 3 parts of allantoin (Allantoin); 10 parts of Mentholums (Menthol); 20 parts of azones; 300 parts of propylene glycol (Propylene Glycol); 7 parts of plant sterols; 100 parts of purified water; Ethanol adds to 1000 parts.
Each material mix homogeneously is obtained to medicine.
The medicine that the embodiment 3 of take is example preparation carries out clinical trial, and result of the test is as follows: take one week as a course for the treatment of, smear every day once;
Visible, medication effect of the present invention is very good.
More than show and described ultimate principle of the present invention, principal character and advantage of the present invention.Those skilled in the art should understand the present invention and not be restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in claimed scope.
Claims (3)
1. hair growth promoting and a hair care external preparation, is characterized in that, 1～7 part of the material ginsenoside (Ginsenoside) who comprises following weight fraction; Soybean isoflavone (Cathe Rine Genistein) 4～7; 40～60 parts of minoxidils (Minoxidil); 1～7 part of allantoin (Allantoin); 6～12 parts of Mentholums (Menthol); 10～30 parts of azones; 200～350 parts of propylene glycol (Propylene Glycol); 1～15 part of plant sterol; 80～120 parts of purified water; Ethanol adds to 1000 parts.
2. a kind of hair growth promoting as claimed in claim 1 and hair care external preparation, is characterized in that, 3 parts of the material ginsenosides (Ginsenoside) who comprises following weight fraction; 5 parts of soybean isoflavone (Cathe Rine Genistein); 50 parts of minoxidils (Minoxidil); 3 parts of allantoin (Allantoin); 10 parts of Mentholums (Menthol); 20 parts of azones; 300 parts of propylene glycol (Propylene Glycol); 7 parts of plant sterols; 100 parts of purified water; Ethanol adds to 1000 parts.
3. arbitrarily described a kind of hair growth promotings and the method for hair care external preparation of preparation claim 1 or 2, is characterized in that, the as above material of ratio is mixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210387061.9A CN103720752A (en) | 2012-10-15 | 2012-10-15 | External preparation used for promoting hair growth and nourishing hair, and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210387061.9A CN103720752A (en) | 2012-10-15 | 2012-10-15 | External preparation used for promoting hair growth and nourishing hair, and preparation method thereof |
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| CN103720752A true CN103720752A (en) | 2014-04-16 |
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| CN201210387061.9A Pending CN103720752A (en) | 2012-10-15 | 2012-10-15 | External preparation used for promoting hair growth and nourishing hair, and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106389519A (en) * | 2016-11-30 | 2017-02-15 | 郑州仁宏医药科技有限公司 | Western medicine compound preparation for treating leukotrichia and alopecia and preparation method thereof |
| CN109010432A (en) * | 2018-10-18 | 2018-12-18 | 苏州工业园区服务外包职业学院 | A kind of Chinese and western medicinal composition of hair growth and its application |
Citations (3)
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| US20020183297A1 (en) * | 2001-02-14 | 2002-12-05 | Niazi Sarfaraz K. | Pharmaceutical composition for the treatment of alopecia |
| WO2005000258A1 (en) * | 2003-06-27 | 2005-01-06 | Amorepacific Corporation | Self-assembled polymeric nanoparticles containing physiologically active ingredients and external application containing the nanoparticles |
| CN1812764A (en) * | 2003-06-27 | 2006-08-02 | 株式会社太平洋 | Self-assembled polymeric nanoparticles containing physiologically active ingredients and external application containing the nanoparticles |
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2012
- 2012-10-15 CN CN201210387061.9A patent/CN103720752A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020183297A1 (en) * | 2001-02-14 | 2002-12-05 | Niazi Sarfaraz K. | Pharmaceutical composition for the treatment of alopecia |
| WO2005000258A1 (en) * | 2003-06-27 | 2005-01-06 | Amorepacific Corporation | Self-assembled polymeric nanoparticles containing physiologically active ingredients and external application containing the nanoparticles |
| CN1812764A (en) * | 2003-06-27 | 2006-08-02 | 株式会社太平洋 | Self-assembled polymeric nanoparticles containing physiologically active ingredients and external application containing the nanoparticles |
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| 颜红侠等: "《日用化学品制造原理与技术》", 28 February 2011, article "生发剂", pages: 207 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106389519A (en) * | 2016-11-30 | 2017-02-15 | 郑州仁宏医药科技有限公司 | Western medicine compound preparation for treating leukotrichia and alopecia and preparation method thereof |
| CN109010432A (en) * | 2018-10-18 | 2018-12-18 | 苏州工业园区服务外包职业学院 | A kind of Chinese and western medicinal composition of hair growth and its application |
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Application publication date: 20140416 |
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