CN103688177B - 狼疮抗凝物检测用血液凝固时间的测定方法 - Google Patents

狼疮抗凝物检测用血液凝固时间的测定方法 Download PDF

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CN103688177B
CN103688177B CN201280029832.5A CN201280029832A CN103688177B CN 103688177 B CN103688177 B CN 103688177B CN 201280029832 A CN201280029832 A CN 201280029832A CN 103688177 B CN103688177 B CN 103688177B
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blood coagulation
blood
time
plasma
reagent
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CN103688177A (zh
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家子正裕
森川千鹤
服部惠子
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SCHOOL JURIDICAL PERSON HIGASHI-NIPPON-GAKUEN
Sekisui Medical Co Ltd
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SCHOOL JURIDICAL PERSON HIGASHI-NIPPON-GAKUEN
Sekisui Medical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201280029832.5A 2011-06-17 2012-06-15 狼疮抗凝物检测用血液凝固时间的测定方法 Active CN103688177B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011135174 2011-06-17
JP2011-135174 2011-06-17
PCT/JP2012/065434 WO2012173260A1 (ja) 2011-06-17 2012-06-15 ループスアンチコアグラント検出用血液凝固時間の測定方法

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CN103688177A CN103688177A (zh) 2014-03-26
CN103688177B true CN103688177B (zh) 2017-07-04

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US (1) US9970046B2 (enExample)
EP (1) EP2722675B1 (enExample)
JP (2) JP5640189B2 (enExample)
KR (1) KR102001662B1 (enExample)
CN (1) CN103688177B (enExample)
CA (1) CA2839125C (enExample)
ES (1) ES2613723T3 (enExample)
WO (1) WO2012173260A1 (enExample)

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JP6564849B2 (ja) 2015-03-20 2019-09-04 株式会社日立ハイテクノロジーズ 自動分析装置及び自動分析方法
JP6871673B2 (ja) * 2015-03-31 2021-05-12 学校法人東日本学園 血液検体を判定するための方法、装置及びコンピュータプログラム、並びに血液検体分析装置
JP6499488B2 (ja) * 2015-03-31 2019-04-10 学校法人東日本学園 凝固時間の測定方法、ループスアンチコアグラントの存否の判定方法及びループスアンチコアグラント検出用試薬キット
WO2017189294A1 (en) 2016-04-25 2017-11-02 Instrumentation Laboratory Company Method and kit for identifying lupus anticoagulant (la) associated with antiphospholipid syndrome
JP6837851B2 (ja) * 2017-01-31 2021-03-03 シスメックス株式会社 血液検体の判定方法、並びに血液検体の分析のための装置及びコンピュータプログラム
CN108761104A (zh) * 2018-05-21 2018-11-06 深圳优迪生物技术有限公司 凝血激活剂及其应用
CN109709344A (zh) * 2018-12-29 2019-05-03 贵州金玖生物技术有限公司 一种活化凝血检测试剂、其制备方法及其应用
CN113366319B (zh) * 2019-01-31 2024-11-19 积水医疗株式会社 血液检体的凝血特性的分析方法
CN112557665B (zh) * 2020-11-10 2023-06-09 北京美创新跃医疗器械有限公司 一种狼疮抗凝物的确认试剂及其制备方法
CN114778858A (zh) * 2022-06-23 2022-07-22 深圳市帝迈生物技术有限公司 一种狼疮抗凝物检测试剂盒

Citations (3)

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US4877741A (en) * 1988-10-24 1989-10-31 The United States Of America As Represented By The Secretary Of The Air Force Treatment of human plasma with brown recluse spider toxin to emulate a lupus anticoagulant
CN1336178A (zh) * 2001-08-16 2002-02-20 四川高维系统工程技术有限公司 凝血因子ⅸ复合物的制备方法
CN101903030A (zh) * 2007-12-21 2010-12-01 灵感生物制药学有限公司 含海藻糖的稳定化因子ix制剂

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DE2461969A1 (de) 1974-12-31 1976-07-08 Behringwerke Ag Stabiles blutplasma, verfahren zu dessen herstellung und seine verwendung als vergleichsplasma bei gerinnungs- untersuchungen
JPH0650999B2 (ja) 1988-09-12 1994-07-06 日本商事株式会社 血液凝固因子安定化法
JP3055933B2 (ja) 1989-07-20 2000-06-26 アナリティカル・コントロール・システムズ・インコーポレーテッド 改良された安定な凝固対照
JPH06324048A (ja) 1993-05-15 1994-11-25 Shimizu Seiyaku Kk 血液凝固能検査用試薬及び血液凝固能の検査方法
DE19749197A1 (de) * 1997-11-07 1999-05-12 Dade Behring Marburg Gmbh Verfahren zur Bestimmung des antikoagulatorischen Potentials einer Probe
US20030044872A1 (en) * 1999-12-24 2003-03-06 Masahiro Okuda Means of stabilizing compositions and reagents
KR101006070B1 (ko) 2001-12-21 2011-01-06 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ⅶ 폴리펩티드의 액체 조성물
RU2364626C2 (ru) 2003-03-18 2009-08-20 Ново Нордиск Хелт Кэр Аг Способ получения, способ очистки и способ стабилизации полипептидов фактора vii, ix и x
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US4877741A (en) * 1988-10-24 1989-10-31 The United States Of America As Represented By The Secretary Of The Air Force Treatment of human plasma with brown recluse spider toxin to emulate a lupus anticoagulant
CN1336178A (zh) * 2001-08-16 2002-02-20 四川高维系统工程技术有限公司 凝血因子ⅸ复合物的制备方法
CN101903030A (zh) * 2007-12-21 2010-12-01 灵感生物制药学有限公司 含海藻糖的稳定化因子ix制剂

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
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血液凝固補正試驗;香川和彥;《檢查と技術》;20060801;第34卷(第8期);第736页右栏第段-739页右栏第2段，图2-图4 *

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Publication number Publication date
JPWO2012173260A1 (ja) 2015-02-23
JP6025105B2 (ja) 2016-11-16
CA2839125C (en) 2019-08-06
US20140127726A1 (en) 2014-05-08
JP2014209134A (ja) 2014-11-06
KR102001662B1 (ko) 2019-10-01
US9970046B2 (en) 2018-05-15
EP2722675B1 (en) 2017-01-11
EP2722675A4 (en) 2015-02-25
KR20140033422A (ko) 2014-03-18
EP2722675A1 (en) 2014-04-23
ES2613723T3 (es) 2017-05-25
WO2012173260A1 (ja) 2012-12-20
CA2839125A1 (en) 2012-12-20
CN103688177A (zh) 2014-03-26
JP5640189B2 (ja) 2014-12-17

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