CN103610764A - Oral liquid containing mango seed extract and preparation method of oral liquid - Google Patents
Oral liquid containing mango seed extract and preparation method of oral liquid Download PDFInfo
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- CN103610764A CN103610764A CN201310620567.4A CN201310620567A CN103610764A CN 103610764 A CN103610764 A CN 103610764A CN 201310620567 A CN201310620567 A CN 201310620567A CN 103610764 A CN103610764 A CN 103610764A
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
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Abstract
The invention discloses an oral liquid containing a mango seed extract and a preparation method of the oral liquid. The preparation method comprises the following steps: cleaning mango seeds serving as a raw material, drying and smashing to 40-60 meshes; adding pure water; and performing ultrasonic extraction, clarifying, filtering, concentrating, and adding 0-10 percent of Chinese herbal medicines and 0.1-0.3 percent of sodium benzoate, sterilizing, sealing and packaging to obtain the oral liquid containing the mango seed extract. The oral liquid containing the mango seed extract is rich in amino acids, proteins, vitamins, anti-microbial substances and immune substances, can be used for preventing and treating diseases of various types of livestock, has particularly remarkable disease prevention and treatment effects during nonreactive feeding of pigs, and has the advantages of simple manufacturing process, saving in energy and time, and easiness in realization of industrial production.
Description
Technical field
The present invention relates to the oral liquid that a kind of domestic animal is used, oral liquid that the natural agricultural byproducts Semen Mangiferae indicae extract of especially take is main constituent and preparation method thereof.
Background technology
At present, domestic animal, poultry farming progressively move towards maximization, scale.And if such aquaculture model, once there is epidemic disease, will soon very fastly spread, cause domestic animal, the large-area morbidity of poultry, to raiser, cause huge economic loss.Therefore, raiser will be so that An ounce of prevention is worth a pound of cure.At present, on market, have the coldrex of preventing and treating of some domestic animal special uses; If Chinese Patent Application No. is 2008100282661 to disclose a kind of preparation method of preventing and treating domestic animal, poultry bird flu oral liquid, the consumption of its raw material is: Fructus Forsythiae 10-20 part, Herba Asari 10-25 part, Radix Ilicis Pubescentis 5-20 part, Rhizoma Anemarrhenae 15-30 part, Flos Chrysanthemi Indici 8-20 part, Radix Polygalae 10-20 part, Herba Lobeliae Chinensis 10-25 part, Fel Serpentis 2-5 part, Fel Bovis seu Bubali 10-25 part, Aloe 40-60 part, crystal sugar 25-40 part, rimantadine 5-15 part, azithromycin 3-10 part.This oral liquid has played good prevention effect to bird flu virus.But its required component is more, must cause its preparation cost can be higher; And its component is Chinese herbal medicine, taken many and also can more or less cause certain influence to the growth of domestic animal/poultry.Therefore, people begin one's study, and some are not only nutritious but also can prevent and treat the composition of medicine of epidemic disease.
Semen Mangiferae indicae: [chemical analysis] kernel is fatty, mainly contain saturated glyceride, monoolein (monoolein), diolein (diolein), glycerol three unsaturated acid esters, its fatty acid composition is: stearic acid (stearic acid), oleic acid (oleic acid), palm fibre is acid (palmitic acid) mutually, arachidic acid (arachidic acid) and a small amount of myristic acid (myristic acid).Still contain sitosterol (sitosterol), starch.Seed is containing oxygen cyanic acid.[function cures mainly] invigorating the stomach and promoting digestion; The circulation of qi promoting of reducing phlegm.Main eating accumulation; Inappetence; Cough; Hernia; Orchitis.Motherland's medical science thinks, Fructus Mangifera Indicae sweet in the mouth acid, cool in nature nontoxic, has clearing away heat and promoting production of body fluid, the diuresis of quenching one's thirst, the functions such as stomach reinforcing preventing or arresting vomiting.Kernel is loose, containing protein 6%, and fat 16%, carbohydrate 69%, can be used as medicine.
According to inventor's inspection information, there is not yet and take Semen Mangiferae indicae and prepare the relevant report of the oral liquid of preventing and treating epidemic disease that domestic animal uses as main material.
Summary of the invention
The object of the present invention is to provide that a kind of domestic animal is special-purpose, diseases prevention and treatment effect is remarkable, oral liquid containing Semen Mangiferae indicae extract that preparation technology is simple, production cost is low and preparation method thereof.
To achieve these goals, the present invention has adopted following technical scheme:
Containing an oral liquid for Semen Mangiferae indicae extract, wherein, in weight fraction, this oral liquid is water containing 5～40% Semen Mangiferae indicae extracts, 0～10% Chinese herbal medicine, 0.1～0.3% sodium benzoate, surplus; Described Chinese herbal medicine is the compositions of one or more any proportioning combinations in Fructus Forsythiae, Semen Juglandis, Flos Lonicerae, Herba Lobeliae Chinensis, penholder grass, Folium Perillae, Herba Plantaginis and Herba Patriniae.
As each constituent content of the present invention preferably: in weight fraction, this oral liquid is water containing 15～30% Semen Mangiferae indicae extracts, 5～10% Chinese herbal medicine, 0.1～0.3% sodium benzoate, surplus.
As of the present invention, further illustrate, above-described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
In oral liquid of the present invention, main effective ingredient is Semen Mangiferae indicae extract, and it contains abundant aminoacid, protein, vitamin, antibacterial and immune material, very remarkable to the diseases prevention and treatment effect of domestic animal especially family pig; And Semen Mangiferae indicae wide material sources, purchasing price are also low, be therefore easy to realize suitability for industrialized production.In order to make the diseases prevention and treatment effect of oral liquid better, can also in oral liquid, add the Chinese herbal medicine of some disease preventing and treating.
Fructus Forsythiae: medicinal plants, stem, leaf, fruit, root all can be used as medicine.It has antibacterial, heart tonifying, diuresis, town the pharmacological action such as to tell, the diseases such as the conventional acute anemopyretic cold of forsythia fruit for treating, carbuncle sore tumefacting virus, tuberculous lymphadenitis, urinary tract infection are the primary raw material of the Chinese medicine preparation such as SHUANGHUANGLIAN KOUFUYE, SHUANGHUANGLIAN FENZHENJI, QINGRE JIEDU KOUFUYE, the careless antipyretic oral liquid of company, flos ionicerae and fructus forsythiae infusion for detoxication.Fructus Forsythiae has broad-spectrum antibacterial action and antiinflammatory action, and staphylococcus aureus, Hayes dysentery bacterium are had to very strong inhibitory action, and other pathogenic bacterium, influenza virus, fungus are had to certain inhibitory action.
Semen Juglandis: have another name called semen juglandis, semen juglandis is containing crude protein 22.18%, and wherein the composition of soluble protein be take glutamic acid as main, is secondly arginine and aspartic acid.Thick lipid 64.23%, wherein neutral lipid accounts for 93.05%; In neutral lipid, triacylglycerol 82.05%, sterolester 3.86%, and in the total fat of free fatty 4.80%. and neutral lipid, fatty acid composition is mainly sub-sour 64.48%-69.95% and oleic acid 13.89%-15.36%; Triacylglycerol institute fatty acids is mainly linolenic acid 69.98; The non-saponification of sterol ester is partly mainly cupreol, and has a small amount of campesterol, stigmasterol, Herba bromi japonici steroid-5-enol, the rare alcohol of bean steroid-7-; Saccharide 13%; Multiple free essential amino acids; Isoleucine, leucine, tryptophan, phenylalanine, valine, threonine and lysine etc., its content is total amino acids 47.50%.Function: the strong body of tonify deficiency, provide nutrition, anti-inflammation and sterilization, maintaining skin, Semen Persicae to have direct inhibiting bacteria and diminishing inflammation effect.According to clinical report, Semen Juglandis is mashed to the Semen Juglandis tar zinc oxide paste of making, treatment dermatitis, eczema, effective percentage can reach 100%.
Flos Lonicerae: Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has the effect of heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treatment wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Herba Lobeliae Chinensis: Herba Lobeliae Chinensis is the whole herb with root of Campanulaceae Herba Lobeliae Chinensis.The effect of Herba Lobeliae Chinensis is heat-clearing and toxic substances removing, inducing diuresis to remove edema.The effect of Herba Lobeliae Chinensis is to control venom, carbuncle furuncle, tonsillitis, warm rash, tinea pedis, traumatic injury.Herba Lobeliae Chinensis another name has half ray flower, arrow bean grass, with the wind flag, monolithic bud, suddenly separate rope, Chinese Lobelia, Herba Lobeliae Chinensis, Herba Hedyotidis Diffusae, fish tail flower, half of chrysanthemum, Herba Pteridis Semipinnatae, milk grass, little Flos Nelumbinis grass, continuous beeweed, blow blood grass, Herba veronicastri villosuli, infantile malnutrition grass, white wax grass skating, golden aster grass, golden pheasant tongue, film clips lotus, Pian Lian, the edible kernel of melon seeds is careless, Serpentis pecks grass, snake is careless.
Penholder grass: have another name called Herba Equiseti Palustris, Radix Glycyrrhizae, containing 15～302 milligrams of % of alkaloid, wherein has equisetine, palustridine, nicotinamide in a small amount etc.Also contain equisetic acid and nimbecetin-8-rhamnose glucose-7-glycoside, MSM, thymus pyrimidine etc.Property is put down, sweet and slightly bitter taste.Effect: dispelling wind, improving eyesight, invigorates blood circulation, relaxing muscles and tendons.Control epiphora induced by wind, pterygium, traumatic injury, hemorrhoidal hamorrhage, internal hemorrhoid with bleeding.
Folium Perillae: call weak, red Soviet Union, common perilla, fragrant Soviet Union etc., formal name used at school Perillafrutescens L., is Labiatae annual herb plant.It can diaphoresis cold expelling to separate pathogenic factor in the exterior, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, resolving depression preventing or arresting vomiting, therefore wind and cold table disease is doublely seen to symptoms of emesis uncomfortable in chest, use this product, be very suitable; Or without table disease, have the stagnation of QI not smooth symptom, also can be used for a surname logical.
Herba Plantaginis: have eliminate the phlegm, antitussive, antiasthmatic effect and resisting pathogenic microbes effect.
Herba Patriniae: i.e. Herba Ixeritis chinensis; Acrid in the mouth, hardship, be slightly cold; Heat-clearing and toxic substances removing, removing heat from blood, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing; For acute appendicitis, the high heat of lung abscess, coughs vomiting bloody pus, pyretic toxicity skin ulcer furuncle, and furuncle is bitterly swollen, breast abdomen pain, appendicitis, enteritis, dysentery, puerperal abdonimal pain, dysmenorrhea.
Sodium benzoate: benzoic acid is called again benzoic acid, therefore sodium benzoate claims again sodium benzoate.Benzoic acid is insoluble in water at normal temperatures, and micro-volatilization in air (particularly hot-air), has hygroscopicity, approximately 0.34g/100ml under room temperature; But be dissolved in hot water; Also be dissolved in ethanol, chloroform and nonvolatile oil.Multiselect sodium benzoate in use; The character of benzoic acid and sodium benzoate and antiseptic property are all similar.Sodium benzoate is mostly white particle, odorless or micro-band Benzoinum abnormal smells from the patient, and taste is micro-sweet, has convergence; (room temperature) soluble in water 53.0g/100ml left and right, PH is in 8 left and right; Sodium benzoate is also acid antiseptic, nothing sterilization, bacteriostasis in alkaline medium; Its anticorrosion best PH is 2.5-4.0, and when PH5.0,5% solution bactericidal effect neither be fine.Sodium benzoate lipophile is larger, and easily permeates cell membranes enters in cyton, and the permeability of interference cell film suppresses cell membrane to amino acid whose absorption; Enter the intracellular alkali storage of cyton internal ionization acidify, and suppress the activity of the respiratory enzyme system of cell, stop S-acetyl-coenzyme-A condensation reaction, thereby play the object of food antiseptic.Sodium benzoate is the antiseptic for oral liquid preparation, the effect that has antiseptic to turn sour, extend the shelf life, and consumption too much can produce harm to human liver, even carcinogenic.According to GB2760-1996 state health standards regulation, in meat system food, must not use sodium benzoate.
A method of preparing the above-mentioned oral liquid containing Semen Mangiferae indicae extract, comprises the following steps:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 40～60 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract, Chinese herbal medicine and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 5～40% Semen Mangiferae indicae extracts, 0～10% Chinese herbal medicine, 0.1～0.3% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Advantage of the present invention:
This Semen Mangiferae indicae extract oral liquid contains abundant aminoacid, protein, vitamin, antibacterial and immune material, integrate nutrition and drug effect, can be used for all kinds of domestic animals prevents and cures diseases, especially for nonreactive, raise pigs, diseases prevention and treatment effect is remarkable, and manufacturing process is simple, energy savings and time, and production cost is low, be easy to realize suitability for industrialized production.
The specific embodiment
Below in conjunction with embodiment, the present invention is further described, but protection scope of the present invention is not limited to these embodiment.
Embodiment 1:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 5% Semen Mangiferae indicae extract, 0.1% sodium benzoate, surplus.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 40 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 5% Semen Mangiferae indicae extract, 0.1% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Embodiment 2:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 40% Semen Mangiferae indicae extract, 0.3% sodium benzoate, surplus.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 60 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 40% Semen Mangiferae indicae extract, 0.3% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Embodiment 3:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 25% Semen Mangiferae indicae extract, 0.2% sodium benzoate, surplus.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 50 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 25% Semen Mangiferae indicae extract, 0.2% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Embodiment 4:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 5% Semen Mangiferae indicae extract, 1% Chinese herbal medicine, 0.1% sodium benzoate, surplus; Described Chinese herbal medicine is that Fructus Forsythiae, Semen Juglandis, Flos Lonicerae, Herba Lobeliae Chinensis, penholder grass, Folium Perillae, Herba Plantaginis and Herba Patriniae are by the compositions of any proportioning combination.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 40 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 5% Semen Mangiferae indicae extract, 1% Chinese herbal medicine, 0.1% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Embodiment 5:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 40% Semen Mangiferae indicae extract, 10% Chinese herbal medicine, 0.3% sodium benzoate, surplus; Described Chinese herbal medicine is that Fructus Forsythiae, Semen Juglandis, Flos Lonicerae, Herba Lobeliae Chinensis, penholder grass, Folium Perillae, Herba Plantaginis and Herba Patriniae are by the compositions of any proportioning combination.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 60 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 40% Semen Mangiferae indicae extract, 10% Chinese herbal medicine, 0.3% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Embodiment 6:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 15% Semen Mangiferae indicae extract, 5% Chinese herbal medicine, 0.3% sodium benzoate, surplus; Described Chinese herbal medicine is that Fructus Forsythiae, Semen Juglandis, Herba Lobeliae Chinensis, penholder grass, Folium Perillae, Herba Plantaginis and Herba Patriniae are by the compositions of any proportioning combination.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 50 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 15% Semen Mangiferae indicae extract, 5% Chinese herbal medicine, 0.3% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Embodiment 7:
Containing an oral liquid for Semen Mangiferae indicae extract, in weight fraction, this oral liquid is water containing 30% Semen Mangiferae indicae extract, 8% Chinese herbal medicine, 0.2% sodium benzoate, surplus; Described Chinese herbal medicine is that Fructus Forsythiae, Semen Juglandis, Flos Lonicerae, Herba Lobeliae Chinensis, penholder grass and Herba Patriniae are by the compositions of any proportioning combination.Described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
The preparation method of being somebody's turn to do the oral liquid that contains Semen Mangiferae indicae extract is as follows:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 40 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 30% Semen Mangiferae indicae extract, 8% Chinese herbal medicine, 0.2% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
Claims (4)
1. containing an oral liquid for Semen Mangiferae indicae extract, it is characterized in that: in weight fraction, this oral liquid is water containing 5～40% Semen Mangiferae indicae extracts, 0～10% Chinese herbal medicine, 0.1～0.3% sodium benzoate, surplus; Described Chinese herbal medicine is one or more compositionss that combine by any proportioning in Fructus Forsythiae, Semen Juglandis, Flos Lonicerae, Herba Lobeliae Chinensis, penholder grass, Folium Perillae, Herba Plantaginis and Herba Patriniae.
2. the oral liquid containing Semen Mangiferae indicae extract according to claim 1, is characterized in that: in weight fraction, this oral liquid is water containing 15～30% Semen Mangiferae indicae extracts, 5～10% Chinese herbal medicine, 0.1～0.3% sodium benzoate, surplus.
3. the oral liquid containing Semen Mangiferae indicae extract according to claim 1 and 2, is characterized in that: described Semen Mangiferae indicae extract is the product that Semen Mangiferae indicae is obtained after cleaning, be dried, pulverize, add water, ultrasonic extraction, clarification, filtration, concentrating.
4. a method of preparing the oral liquid containing Semen Mangiferae indicae extract as described in as arbitrary in claim 1-3, is characterized in that: comprise the following steps:
(1) extraction of Semen Mangiferae indicae extract
After Semen Mangiferae indicae is cleaned up, be dried, pulverize, then cross 40～60 orders, add water, ultrasonic extraction, clarification, filtration, the concentrated rear Semen Mangiferae indicae extract that obtains;
(2) Semen Mangiferae indicae extract, Chinese herbal medicine and the sodium benzoate that step (1) are extracted are soluble in water, and configuration is containing the semi-finished product oral liquid of 5～40% Semen Mangiferae indicae extracts, 0～10% Chinese herbal medicine, 0.1～0.3% sodium benzoate;
(3) the semi-finished product oral liquid of step (2) is carried out to sterilizing, encapsulation, obtain finished product oral liquid.
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