CN107019737A - A kind of oral liquid containing Semen Litchi extract and preparation method thereof - Google Patents
A kind of oral liquid containing Semen Litchi extract and preparation method thereof Download PDFInfo
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- CN107019737A CN107019737A CN201610060062.0A CN201610060062A CN107019737A CN 107019737 A CN107019737 A CN 107019737A CN 201610060062 A CN201610060062 A CN 201610060062A CN 107019737 A CN107019737 A CN 107019737A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A61K36/52—Juglandaceae (Walnut family)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a kind of oral liquid containing Semen Litchi extract and preparation method thereof, using semen litchi as primary raw material, described preparation method is, semen litchi is cleaned, dried, 40-60 mesh is crushed to, by adding the Semen Litchi extract oral liquid obtained after pure water, the technical process such as ultrasonic wave extraction, clarification, filtering, concentration, 0~10% Chinese herbal medicine of addition and 0.1~0.3% sodium benzoate, sterilizing encapsulation.The Semen Litchi extract oral liquid contains abundant amino acid, protein, vitamin, antibacterial and immune substance, is prevented and cured diseases available for all kinds of domestic animals, is particularly raised pigs for nonreactive, disease prevention and cure effect is notable, manufacturing process is simple, saves the energy and time, it is easy to accomplish industrialized production.
Description
Technical field
The present invention relates to a kind of oral liquid of domestic animal, especially using natural agricultural byproducts Semen Litchi extract as oral liquid of principal component and preparation method thereof.
Background technology
At present, domestic animal, poultry farming progressively move towards maximization, scale.And such aquaculture model, it if once occurring epidemic disease, very fast will soon spread, cause domestic animal, the morbidity of poultry large area, huge economic loss is caused to raiser.Therefore, raiser will be so that An ounce of prevention is worth a pound of cure.At present, what some existing domestic animals of in the market were special prevents and treats cold drug;Such as Chinese Patent Application No. discloses a kind of preventing and treating domestic animal, the preparation method of poultry bird flu oral liquid for 2008100282661, and the consumption of its raw material is:10-20 parts of the capsule of weeping forsythia, 10-25 parts of asarum, 5-20 parts of ilex pubescens, 15-30 parts of the wind-weed, 8-20 parts of chrysanthemum indicum, 10-20 parts of polygala, 10-25 parts of Chinese lobelia, 2-5 parts of snake gall, 10-25 parts of ox courage, 40-60 parts of aloe, 25-40 parts of rock sugar, 5-15 parts of Rimantadine, 3-10 parts of azithromycin.The oral liquid serves preferable prevention effect to avian influenza virus.But, its required component is more, and necessarily causing it to prepare cost can be higher;And its component is Chinese herbal medicine, having taken more the growth on domestic animal/poultry also can more or less cause certain influence.Therefore, people begin one's study, and some are not only nutritious but also can prevent and treat the composition of medicine of epidemic disease.
Semen litchi, Chinese medicine name.For sapindaceous plant lichee Litchi chinensis Sonn. dry mature seed.Summer harvesting ripe fruit, removes pericarp and meat aril, cleans, dries.This product is in Long Circle or oval, slightly flat, long 1.5~2.2cm, 1~1.5cm of diameter.Surface brownish red or purple brown, it is smoothly, glossy, slightly it is recessed and insertion waves, there are the hilum of similar round yellowish-brown, diameter about 7mm in one end.Matter is hard.Cotyledon 2, brown color.Gas is micro-, taste micro-sweet, hardship, puckery.With promoting the circulation of qi dissipating bind, cold-dispelling pain-relieving effect, available for cold hernia stomachache, testiclar gall.
According to inventor's inspection information, there is not yet preparing the relevant report of the oral liquid for preventing and treating epidemic disease of domestic animal by main material of semen litchi.
The content of the invention
It is an object of the invention to provide a kind of domestic animal is special, disease prevention and cure effect significantly, preparation technology is simple, the low oral liquid containing Semen Litchi extract of production cost and preparation method thereof.
To achieve these goals, present invention employs following technical scheme:
A kind of oral liquid containing Semen Litchi extract, wherein, in terms of weight fraction, the oral liquid is water containing 5~40% Semen Litchi extracts, 0~10% Chinese herbal medicine, 0.1~0.3% sodium benzoate, surplus;Described Chinese herbal medicine is the composition of one or both of the capsule of weeping forsythia, walnut kernel, honeysuckle, Chinese lobelia, penholder grass, purple perilla, Asiatic plantain and field pennycress any of the above proportioning combination.
It is used as the preferred of each component content of the present invention:In terms of weight fraction, the oral liquid is water containing 15~30% Semen Litchi extracts, 5~10% Chinese herbal medicines, 0.1~0.3% sodium benzoate, surplus.
As further illustrating for the present invention, above-described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
In the oral liquid of the present invention, principle active component is Semen Litchi extract, and it contains abundant amino acid, protein, vitamin, antibacterial and immune substance, and the disease prevention and cure effect to domestic animal especially hog is very notable;And semen litchi wide material sources, purchasing price are also low, therefore it is easily achieved industrialized production.In order to make the disease prevention and cure of oral liquid better, the Chinese herbal medicine of some disease preventing and treatings can also be added in oral liquid.
The capsule of weeping forsythia:Medicinal plant, stem, leaf, fruit, root can be used as medicine.Its pharmacological action such as there is antibacterial, cardiac stimulant, diuresis, town to tell, the diseases such as the acute anemopyretic cold of conventional forsythia fruit for treating, carbuncle sore tumefacting virus, scrofula, urinary tract infections, are Shuanghuanglian oral liquid, dual coptis powder, heat-clearing and detoxicating oral liquid, the primary raw material for connecting the Chinese medicine preparations such as careless antipyretic oral liquid, flos ionicerae and fructus forsythiae infusion for detoxication.The capsule of weeping forsythia has broad-spectrum antibacterial action and antiinflammatory action, there is very strong inhibitory action to staphylococcus aureus, Hayes shigella dysenteriae, has certain inhibitory action to other pathogenic bacteria, influenza virus, fungi.
Walnut kernel:Also known as juglandis,semen, juglandis,semen is containing crude protein 22.18%, and the wherein composition of soluble protein is arginine and aspartic acid based on glutamic acid, secondly.Thick lipid 64.23%, wherein neutral lipid accounts for 93.05%;Aliphatic acid composition is mainly Asia acid 64.48%-69.95% and oleic acid 13.89%-15.36% in triacylglycerol 82.05% in neutral lipid, sterol ester 3.86%, the total fat of free fatty 4.80%. and neutral lipid;Triacylglycerol institute fatty acids are mainly leukotrienes 69.98;Sterol ester non-saponified portions is mainly cupreol, and has a small amount of campesterol, stigmasterol, oat steroid -5- enols, beans steroid -7- dilute alcohols;Carbohydrate 13%;A variety of free essential amino acids;Isoleucine, leucine, tryptophan, phenylalanine, valine, threonine and lysine etc., its content are the 47.50% of total amino acid.Function:The strong body of qi-restoratives, offer nutrition, anti-inflammation and sterilization, maintaining skin, Semen Persicae have direct inhibiting bacteria and diminishing inflammation to act on.According to clinical report, walnut kernel is mashed to the walnut tar zinc oxide paste being made, treatment dermatitis, eczema are efficient up to 100%.
Honeysuckle:Honeysuckle is cold in nature, sweet, enters lung, the heart, stomach, has effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treat wind, cures mainly disease under turgor, warm disease heating, the disease such as heat toxin large carbuncle and tumour.It has certain curative effect for illnesss such as dizzy dizziness, thirst, hidrosis unhappiness, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, parotitis, suppurative tonsillitis.
Chinese lobelia:Chinese lobelia is the whole herb with root of Campanulaceae Chinese lobelia.Effect of Chinese lobelia is clearing heat and detoxicating, inducing diuresis for removing edema.The effect of Chinese lobelia is to control venomous snake bite, carbuncle swells furunculosis, tonsillitis, warm rash, tinea pedis, traumatic injury.Chinese lobelia alias has half of flower, arrow beans grass, flag, monolithic bud, anxious solution rope, Hedyotis diffusa Willd, thin rice grass, HERBA HEDYOTIS DIFFUSAE, fish tail flower, half of chrysanthemum, Semi-pinnated Brake Herb, milk is careless with the wind, small lotus flower grass, continuous beeweed, blow that blood grass, Veronicastrum Herb, infantile malnutrition due to digestive disturbances or intestinalparasites are careless, cured grass skating, golden aster grass, golden pheasant tongue, film clips lotus, Pian Lian, the edible kernel of melon seeds be careless in vain, snake pecks careless, long cordyceps sinensis.
Penholder grass:Also known as marsh horsetail herb, hay 15~302 milligrams of % containing alkaloid, wherein having equisetine, palustridine, a small amount of nicotinamides etc..Also containing aconitic acid and Kaempferol -8- rhamnose glucose -7- glycosides, MSM, thymidine etc..It is mild-natured, sweet and slightly bitter taste.Effect:Dispelling wind, improving eyesight, promoting blood circulation, relaxing muscles and tendons.Control tearing against wind, pterygium, traumatic injury, intestines wind, bleeding.
Purple perilla:Alias is weak, red Soviet Union, common perilla, fragrant Soviet Union etc., scientific name
Perillafrutescens L., are Labiatae annual herb plant.It can sweating cold dispelling it is evil with inducing diaphoresis, and can promoting the circulation of qi it is wide in, solve strongly fragrant preventing or arresting vomiting, it is therefore simultaneous seeing symptoms of emesis uncomfortable in chest to chill table disease, be very much suitable using this product;Or have the not smooth symptom of the stagnation of the circulation of vital energy without table disease, it can also be used to Xuan Tong.
Asiatic plantain:With the effect of eliminating the phlegm, antibechic, antiasthmatic effect and resisting pathogenic microbes.
Field pennycress:That is Chinese ixeris herb;Pungent, hardship, is slightly cold;It is clearing heat and detoxicating, cool blood, the carbuncle that disappears apocenosis, stasis-dispelling and pain-killing;For acute appendicitis, lung carbuncle hyperpyrexia coughs vomiting of pus and blood, and heat toxin sore malignant boil, boil pain is swollen, chest and abdomen pain, appendicitis, enteritis, dysentery, postpartum abdominal pain, dysmenorrhoea.
Sodium benzoate:Benzoic acid is also known as benzoic acid, therefore sodium benzoate is also known as sodium benzoate.Benzoic acid is insoluble in water at normal temperatures, in air(Particularly hot-air)In micro- volatilization, have hygroscopicity, about 0.34g/100ml under normal temperature;But it is dissolved in hot water;It also is soluble in ethanol, chloroform and nonvolatile oil.It is in use to select sodium benzoate more;The character and antiseptic property of benzoic acid and sodium benzoate are all similar.Sodium benzoate is mostly white particle, odorless or micro-strip styrax smell, and the micro- sweet tea of taste has convergence;It is soluble in water(Normal temperature)53.0g/100ml left and right, PH is 8 or so;Sodium benzoate is also acid preservative, without sterilization, bacteriostasis in alkaline medium;The optimal PH of its anti-corrosion is 2.5-4.0, and in PH5.0,5% solution bactericidal effect is nor very well.Sodium benzoate lipophile is larger, and easy penetration cell film enters in cell body, the permeability of interference cell film, suppresses absorption of the cell membrane to amino acid;Intracellular alkali storage is acidified into cell body internal ionization, and suppresses the activity of the breathing enzyme system of cell, acetyl coenzyme A condensation reaction is prevented, so as to play the purpose of food antiseptic.Sodium benzoate is the preservative for oral liquid preparation, and having prevents the rotten effect turned sour, extended the shelf life, and consumption excessively can produce harm to human liver, or even carcinogenic.
Provided according to the state health standards of GB2760-1996, sodium benzoate must not be used in meat system food.
A kind of method for preparing the above-mentioned oral liquid containing Semen Litchi extract, comprises the following steps:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 40~60 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract of extraction, Chinese herbal medicine and sodium benzoate are soluble in water, and configuration contains 5~40% Semen Litchi extracts, 0~10% Chinese herbal medicine, the semi-finished product oral liquid of 0.1~0.3% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Advantages of the present invention:
The Semen Litchi extract oral liquid contains abundant amino acid, protein, vitamin, antibacterial and immune substance, integrate nutrition and drug effect, prevented and cured diseases available for all kinds of domestic animals, particularly it is used to nonreactive raise pigs, significantly, manufacturing process is simple for disease prevention and cure effect, saves the energy and time, and production cost is low, it is easy to accomplish industrialized production.
Embodiment
With reference to embodiment, the present invention is further described, but protection scope of the present invention is not limited to these embodiments.
Embodiment 1:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 5% Semen Litchi extract, 0.1% sodium benzoate, surplus.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 40 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 5% Semen Litchi extract, the semi-finished product oral liquid of 0.1% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Embodiment 2:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 40% Semen Litchi extract, 0.3% sodium benzoate, surplus.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 60 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 40% Semen Litchi extract, the semi-finished product oral liquid of 0.3% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Embodiment 3:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 25% Semen Litchi extract, 0.2% sodium benzoate, surplus.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 50 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 25% Semen Litchi extract, the semi-finished product oral liquid of 0.2% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Embodiment 4:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 5% Semen Litchi extract, 1% Chinese herbal medicine, 0.1% sodium benzoate, surplus;Described Chinese herbal medicine is the composition of the capsule of weeping forsythia, walnut kernel, honeysuckle, Chinese lobelia, penholder grass, purple perilla, Asiatic plantain and field pennycress by any proportioning combination.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 40 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 5% Semen Litchi extract, 1% Chinese herbal medicine, the semi-finished product oral liquid of 0.1% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Embodiment 5:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 40% Semen Litchi extract, 10% Chinese herbal medicine, 0.3% sodium benzoate, surplus;Described Chinese herbal medicine is the composition of the capsule of weeping forsythia, walnut kernel, honeysuckle, Chinese lobelia, penholder grass, purple perilla, Asiatic plantain and field pennycress by any proportioning combination.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 60 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 40% Semen Litchi extract, 10% Chinese herbal medicine, the semi-finished product oral liquid of 0.3% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Embodiment 6:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 15% Semen Litchi extract, 5% Chinese herbal medicine, 0.3% sodium benzoate, surplus;Described Chinese herbal medicine is the composition of the capsule of weeping forsythia, walnut kernel, Chinese lobelia, penholder grass, purple perilla, Asiatic plantain and field pennycress by any proportioning combination.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 50 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 15% Semen Litchi extract, 5% Chinese herbal medicine, the semi-finished product oral liquid of 0.3% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Embodiment 7:
A kind of oral liquid containing Semen Litchi extract, in terms of weight fraction, the oral liquid is water containing 30% Semen Litchi extract, 8% Chinese herbal medicine, 0.2% sodium benzoate, surplus;Described Chinese herbal medicine is the composition of the capsule of weeping forsythia, walnut kernel, honeysuckle, Chinese lobelia, penholder grass and field pennycress by any proportioning combination.Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
The preparation method of the oral liquid containing Semen Litchi extract is as follows:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 40 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract and sodium benzoate of extraction are soluble in water, and configuration contains 30% Semen Litchi extract, 8% Chinese herbal medicine, the semi-finished product oral liquid of 0.2% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
Claims (4)
1. a kind of oral liquid containing Semen Litchi extract, it is characterised in that:In terms of weight fraction, the oral liquid is water containing 5~40% Semen Litchi extracts, 0~10% Chinese herbal medicine, 0.1~0.3% sodium benzoate, surplus;Described Chinese herbal medicine is more than one or both of the capsule of weeping forsythia, walnut kernel, honeysuckle, Chinese lobelia, penholder grass, purple perilla, the Asiatic plantain and field pennycress composition by any proportioning combination.
2. the oral liquid according to claim 1 containing Semen Litchi extract, it is characterised in that:In terms of weight fraction, the oral liquid is water containing 15~30% Semen Litchi extracts, 5~10% Chinese herbal medicines, 0.1~0.3% sodium benzoate, surplus.
3. the oral liquid according to claim 1 or 2 containing Semen Litchi extract, it is characterised in that:Described Semen Litchi extract be by semen litchi it is cleaned, dry, crush, add water, ultrasonic wave extraction, clarification, filtering, the product obtained after concentration.
4. a kind of method for preparing the oral liquid containing Semen Litchi extract as described in claim 1-3 is any, it is characterised in that:Comprise the following steps:
(1)The extraction of Semen Litchi extract
After semen litchi is cleaned up, it is dried, crushes, then cross 40~60 mesh, adds water, ultrasonic wave extraction, clarification, filtering, obtains Semen Litchi extract after concentration;
(2)By step(1)The Semen Litchi extract of extraction, Chinese herbal medicine and sodium benzoate are soluble in water, and configuration contains 5~40% Semen Litchi extracts, 0~10% Chinese herbal medicine, the semi-finished product oral liquid of 0.1~0.3% sodium benzoate;
(3)By step(2)Semi-finished product oral liquid sterilized, encapsulated, that is, obtain finished product oral liquid.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109181934A (en) * | 2018-09-30 | 2019-01-11 | 广西秀美壮乡能源环保有限公司 | A kind of Brewing equipment of fen-flavor type white spirit |
US10568866B1 (en) * | 2018-10-05 | 2020-02-25 | Matthias W. Rath | Composition and its use for increasing innate immune health |
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2016
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109181934A (en) * | 2018-09-30 | 2019-01-11 | 广西秀美壮乡能源环保有限公司 | A kind of Brewing equipment of fen-flavor type white spirit |
US10568866B1 (en) * | 2018-10-05 | 2020-02-25 | Matthias W. Rath | Composition and its use for increasing innate immune health |
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