CN105726689A - Antiviral oral liquid for livestock and preparation method thereof - Google Patents
Antiviral oral liquid for livestock and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/08—Solutions
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
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Abstract
The invention relates to an antiviral oral liquid for livestock and a preparation method thereof. The antiviral oral liquid for livestock is mainly prepared by mixing the following components in parts by weight: 40-60 parts of mango leaves, 20-40 parts of papaya leaves, 3-20 parts of leaves of balsam pear and 0.1-0.3 part of sodium benzoate. The production method comprises the steps of cleaning and drying the components, grinding the components until the grain size is 40-60 mesh, adding purified water, carrying out ultrasonic extraction, clarification, filtration and concentration, adding 0.1-0.3% of sodium benzoate and carrying out sterilization and packaging, thus obtaining the antiviral oral liquid for livestock. The antiviral oral liquid for livestock and the preparation method have the advantages that the oral liquid contains mangiferin, chlorogenic acid, flavones, momordicosides and immune substances, can be used for preventing and curing various viral diseases of livestock, is especially used for non-antibiotic pig raising and has obvious disease control effects; and the preparation process is simple, has the effect of saving energy and time and easily achieves industrial production.
Description
Technical field
The present invention relates to the oral liquid of a kind of domestic animal, especially with natural agricultural byproducts Folium mangiferae, leaf of Fructus Chaenomelis, the Folium Momordicae Charantiae extract oral liquid as main constituent and preparation method thereof.
Background technology
At present, domestic animal, poultry farming progressively move towards maximization, scale.And such aquaculture model, if once there is epidemic disease, very fast will soon spread, causing the large-area morbidity of domestic animal, poultry, cause huge economic loss to raiser.Therefore, raiser will be so that An ounce of prevention is worth a pound of cure.At present, the antivirus oral liquid that on market, more existing domestic animals are special；If Chinese Patent Application No. is 2008100282661 to disclose and a kind of prevent and treat domestic animal, the preparation method of poultry bird flu oral liquid, the consumption of its raw material is: Fructus Forsythiae 10-20 part, Herba Asari 10-25 part, Radix Ilicis Pubescentis 5-20 part, Rhizoma Anemarrhenae 15-30 part, Flos Chrysanthemi Indici 8-20 part, Radix Polygalae 10-20 part, Herba Lobeliae Chinensis 10-25 part, Fel Serpentis 2-5 part, Fel Bovis seu Bubali 10-25 part, Aloe 40-60 part, crystal sugar 25-40 part, rimantadine 5-15 part, azithromycin 3-10 part.This oral liquid serves preferable prevention effect to bird flu virus.But, needed for it, component is more, necessarily causes its preparation cost can be higher；And its component is Chinese herbal medicine, how takes the growth on domestic animal/poultry and also can more or less cause certain impact.Therefore, people begin one's study, and some are the most nutritious but also can prevent and treat the composition of medicine of epidemic disease.
Folium mangiferae be plantation Fructus Mangifera Indicae during results agricultural byproducts, mango is aiphyllium, for tropical fruit tree, cultivates in South China, by village, various places, Guangdong or room residence, plant of being somewhat scattered about like the stars seen from moistening soil.Fructus Mangifera Indicae (MangiferaindicaL.) is Anacardiaceae Mangifera tropical evergreen megaphanerophyte, Fructus Mangifera Indicae distribution is the widest, having more than 70 country to produce Fructus Mangifera Indicae in the world, the Taiwan of China, Guangdong, Guangxi, Hainan, south Fujian and south of Yunnan have Fructus Mangifera Indicae to plant, and resource is the abundantest.The fruit of Fructus Mangifera Indicae plant, pit, bark and leaf all hyoscines and have uniqueness pharmacologically active, modern pharmacology research shows, mango leaf extract have relieving asthma, cough-relieving, eliminate the phlegm, antiinflammatory, analgesia, the effect such as antibacterial, antiviral, antitumor, clinical practice shows, mango leaf extract has good curative effect to respiratory inflammation and cold cough.The chemical composition forefathers of Folium mangiferae have been reported: nineteen eighty-two, containing 8 phenolic compounds such as chimonin, homomangiferin, Isomangiferin, Quercetins in report Fructus Mangifera Indicae (MangiferaindicaL.) leaf such as Lu Zhongyi, and point out that chimonin is the principle active component of Folium mangiferae.
Have for the Patents report of cultivated animals currently for Folium mangiferae:
CN201010563121.9, Main classification A23K1/18 (2006.01) I, a kind of composite immune reinforcing agent improving Mylopharyngodon piceus anti-stress and preparation method thereof；
CN201310174349.2, Main classification A23K1/18 (2006.01) I, for improving the preparation method of the feed additive of the digestive function of goose.
Leaf of Fructus Chaenomelis be plantation Fructus Chaenomelis during results agricultural byproducts, central containing abundant nutritional labeling；Main component includes: containing alkaloid, inside has carpaine, pseudocarpaine, dehydrogenation carpaine (dehydrocapaine) I and II, choline (choline), also contains carotenoid, globulariacitrin (rutin).Again containing aminoacid: agedoite (asparagine), leucine (leucine), phenylalanine (pheny-lalanine), valine (valine), methionine (methionine), alanine (alanine), beta Alanine (β-alanine), butyrine (α-aminobutyric acid), glutamic acid (glutamic acid), aspartic acid (aspartic acid).Leaf of Fructus Chaenomelis mixed feed can promote the health of domestic animal, Fast Growth, nontoxic secondary residual, helps domestic animal resist the disease.
Folium Momordicae Charantiae be plantation Fructus Momordicae charantiae during results agricultural byproducts, central containing abundant nutritional labeling；Main component includes: containing alkaloid, inside has a kind momordicine, pseudo-kind momordicine, dehydrogenation kind momordicine (dehydrocapaine) I and II, choline (choline), also contains carotenoid, globulariacitrin (rutin).Again containing aminoacid: agedoite (asparagine), leucine (leucine), phenylalanine (pheny-lalanine), valine (valine), methionine (methionine), alanine (alanine), beta Alanine (β-alanine), butyrine (α-aminobutyric acid), glutamic acid (glutamic acid), aspartic acid (aspartic acid).Folium Momordicae Charantiae composite feed additive can promote the health of domestic animal, Fast Growth, nontoxic secondary residual, helps domestic animal resist the disease.
According to inventor's inspection information, there is not yet the relevant report of the oral liquid preventing and treating epidemic disease preparing domestic animal with Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae for main material.
Summary of the invention
It is an object of the invention to provide that a kind of domestic animal is special, diseases prevention and treatment effect notable, antivirus veterinary oral liquid that preparation technology is simple, production cost is low and preparation method thereof.
To achieve these goals, present invention employs techniques below scheme:
A kind of antivirus veterinary oral liquid, it is characterized in that: this oral liquid is containing 20～80% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, and this extract is formed by terms of weight fraction: 40～60 parts of Folium mangiferaes, 20～40 parts of leaf of Fructus Chaenomelis, 3～20 parts of Folium Momordicae Charantiaes, 0.1～0.3 part of sodium benzoate..
Preferred as each constituent content of the present invention: in terms of weight fraction, in terms of weight fraction, this oral liquid is containing 20～80% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, and this extract is formed by terms of weight fraction: 40 parts of Folium mangiferaes, 40 parts of leaf of Fructus Chaenomelis, 20 parts of Folium Momordicae Charantiaes, 0.1 part of sodium benzoate.
Further illustrating as the present invention, above-described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
In the oral liquid of the present invention, principle active component is Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, and it contains abundant aminoacid, protein, vitamin, antibacterial and immune material, the most notable to the diseases prevention and treatment effect of domestic animal especially family pig；And Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae wide material sources, purchasing price are the lowest, are thus susceptible to realize industrialized production.In order to make the diseases prevention and treatment of oral liquid better, it is also possible to add some sweeting agents in oral liquid.
Sodium benzoate: benzoic acid is also called benzoic acid, therefore sodium benzoate is also known as sodium benzoate.Benzoic acid is insoluble in water at normal temperatures, micro-volatilization in air (particularly hot-air), has hygroscopicity, about 0.34g/100ml under room temperature；But it is dissolved in hot water；It also is soluble in ethanol, chloroform and nonvolatile oil.In use select sodium benzoate more；Benzoic acid and the character of sodium benzoate and antiseptic property are the most similar.Sodium benzoate is mostly white particle, odorless or micro-strip Benzoinum abnormal smells from the patient, and taste is micro-sweet, has convergence；(room temperature) soluble in water about 53.0g/100ml, PH is about 8；Sodium benzoate is also acid preservative, without sterilization, bacteriostasis in alkaline medium；The optimal PH of its anticorrosion is 2.5-4.0, and when PH5.0, the solution bactericidal effect of 5% is not fine.Sodium benzoate is the preservative for oral liquid preparation, has and prevents the rotten effect turned sour, extend the shelf life.
A kind of method preparing above-mentioned antivirus veterinary oral liquid, comprises the following steps:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae are cleaned up, be dried, pulverize, then cross 40～60 mesh, add water 5-10 times, ultrasonic extraction, clarify, filter, concentrate after acquisition antivirus veterinary extract concentrated solution；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.1～0.3% sodium benzoate be dissolved in wherein or be dissolved in water after be added thereto, configuration is containing 20～80% semi-finished product oral liquid of antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
Advantages of the present invention:
This Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract oral liquid contain abundant aminoacid, protein, vitamin, antibacterial and immune material, integrate nutrition and drug effect, can be used for all kinds of domestic animal to prevent and cure diseases, cultivate especially for nonreactive, diseases prevention and treatment effect is notable, and manufacturing process is simple, saves the energy and time, and production cost is low, it is easy to accomplish industrialized production.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described, but protection scope of the present invention is not limited to these embodiments.
Embodiment 1:
A kind of antivirus veterinary oral liquid, in terms of weight fraction, this oral liquid is water containing 20% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, 0.1% sodium benzoate, surplus.Described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
The preparation method of this antivirus veterinary oral liquid is as follows:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After 40 parts of Folium mangiferaes, 40 parts of leaf of Fructus Chaenomelis, 20 parts of Folium Momordicae Charantiaes are cleaned up, be dried, pulverize, then cross 40 mesh, add water, ultrasonic extraction, clarify, filter, concentrate after obtain Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.1% sodium benzoate is added thereto after being dissolved in wherein or being dissolved in water, the configuration semi-finished product oral liquid containing 20% antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
Embodiment 2:
A kind of antivirus veterinary oral liquid, in terms of weight fraction, this oral liquid is water containing 80% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, 0.1% sodium benzoate, surplus.Described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
The preparation method of this antivirus veterinary oral liquid is as follows:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After 60 parts of Folium mangiferaes, 20 parts of leaf of Fructus Chaenomelis, 20 parts of Folium Momordicae Charantiae leaves are cleaned up, be dried, pulverize, then cross 60 mesh, add water, ultrasonic extraction, clarify, filter, concentrate after obtain Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.1% sodium benzoate is added thereto after being dissolved in wherein or being dissolved in water, the configuration semi-finished product oral liquid containing 80% antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
Embodiment 3:
A kind of antivirus veterinary oral liquid, in terms of weight fraction, this oral liquid is water containing 50% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, 0.1% sodium benzoate, surplus.Described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
The preparation method of this antivirus veterinary oral liquid is as follows:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After 50 parts of Folium mangiferaes, 30 parts of leaf of Fructus Chaenomelis, 10 parts of Folium Momordicae Charantiaes are cleaned up, be dried, pulverize, then cross 40 mesh, add water, ultrasonic extraction, clarify, filter, concentrate after obtain Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.1% sodium benzoate is added thereto after being dissolved in wherein or being dissolved in water, the configuration semi-finished product oral liquid containing 50% antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
Embodiment 4:
A kind of antivirus veterinary oral liquid, in terms of weight fraction, this oral liquid is water containing 50% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, 0.1% sodium benzoate, surplus.Described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
The preparation method of this antivirus veterinary oral liquid is as follows:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After 45 parts of Folium mangiferaes, 35 parts of leaf of Fructus Chaenomelis, 10 parts of Folium Momordicae Charantiaes are cleaned up, be dried, pulverize, then cross 40 mesh, add water, ultrasonic extraction, clarify, filter, concentrate after obtain Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.2% sodium benzoate is added thereto after being dissolved in wherein or being dissolved in water, the configuration semi-finished product oral liquid containing 50% antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
Embodiment 5:
A kind of antivirus veterinary oral liquid, in terms of weight fraction, this oral liquid is water containing 50% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, 0.1% sodium benzoate, surplus.Described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
The preparation method of this antivirus veterinary oral liquid is as follows:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After 60 parts of Folium mangiferaes, 37 parts of leaf of Fructus Chaenomelis, 3 parts of Folium Momordicae Charantiaes are cleaned up, be dried, pulverize, then cross 40 mesh, add water, ultrasonic extraction, clarify, filter, concentrate after obtain Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.3% sodium benzoate is added thereto after being dissolved in wherein or being dissolved in water, the configuration semi-finished product oral liquid containing 50% antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
Claims (4)
1. an antivirus veterinary oral liquid, it is characterized in that: this oral liquid is containing 20～80% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, and this extract is formed by terms of weight fraction: 40～60 parts of Folium mangiferaes, 20～40 parts of leaf of Fructus Chaenomelis, 3～20 parts of Folium Momordicae Charantiaes, 0.1～0.3 part of sodium benzoate.
Antivirus veterinary oral liquid the most according to claim 1, it is characterized in that: in terms of weight fraction, this oral liquid is containing 20～80% Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract, and this extract is formed by terms of weight fraction: 40 parts of Folium mangiferaes, 40 parts of leaf of Fructus Chaenomelis, 20 parts of Folium Momordicae Charantiaes, 0.1 part of sodium benzoate.
Antivirus veterinary oral liquid the most according to claim 1 and 2, it is characterised in that: described Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract be by Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae is cleaned, be dried, pulverize, add water, ultrasonic extraction, clarify, filter, concentrate the product obtained afterwards.
4. the method for the antivirus veterinary oral liquid that a kind is prepared as described in claim 1-3 is arbitrary, it is characterised in that: comprise the following steps:
(1) extraction of Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract
After Folium mangiferae, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae are cleaned up, be dried, pulverize, then cross 40～60 mesh, add water 5-10 times, ultrasonic extraction, clarify, filter, concentrate after acquisition antivirus veterinary extract concentrated solution；
(2) Folium mangiferae that step (1) extracted, leaf of Fructus Chaenomelis, Folium Momordicae Charantiae extract concentrated solution, 0.1～0.3% sodium benzoate be dissolved in wherein or be dissolved in water after be added thereto, configuration is containing 20～80% semi-finished product oral liquid of antivirus extract concentrated solution；
(3) the semi-finished product oral liquid of step (2) is carried out sterilizing, encapsulation, i.e. obtain finished product oral liquid.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038666A (en) * | 2016-07-29 | 2016-10-26 | 桂林实力科技有限公司 | Bitter melon leaf extract and application thereof |
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