CN1036009C - 2-噻吩基咪唑并[2，1-b]苯并噻唑-3-乙酸衍生物，其制备方法及其药用 - Google Patents

2-噻吩基咪唑并[2，1-b]苯并噻唑-3-乙酸衍生物，其制备方法及其药用 Download PDF

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Publication number
CN1036009C
CN1036009C CN93121519A CN93121519A CN1036009C CN 1036009 C CN1036009 C CN 1036009C CN 93121519 A CN93121519 A CN 93121519A CN 93121519 A CN93121519 A CN 93121519A CN 1036009 C CN1036009 C CN 1036009C
Authority
CN
China
Prior art keywords
formula
benzothiazole
compound
imidazo
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN93121519A
Other languages
English (en)
Chinese (zh)
Other versions
CN1096029A (zh
Inventor
M·塞夫林
C·莫雷尔
M·曼加尼
P·乔治
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SYNTHETIC LABORATORY CORP
Synthelabo SA
Original Assignee
SYNTHETIC LABORATORY CORP
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Filing date
Publication date
Application filed by SYNTHETIC LABORATORY CORP filed Critical SYNTHETIC LABORATORY CORP
Publication of CN1096029A publication Critical patent/CN1096029A/zh
Application granted granted Critical
Publication of CN1036009C publication Critical patent/CN1036009C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Weting (AREA)
  • Diffracting Gratings Or Hologram Optical Elements (AREA)
CN93121519A 1992-12-30 1993-12-29 2-噻吩基咪唑并[2，1-b]苯并噻唑-3-乙酸衍生物，其制备方法及其药用 Expired - Fee Related CN1036009C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9215889 1992-12-30
FR9215889A FR2699921B1 (fr) 1992-12-30 1992-12-30 Dérivés d'acide 2-(thien-2-yl)imidazo[2,1-b]benzothiazole-3-acétique, leur préparation et leur application en thérapeutique.

Publications (2)

Publication Number Publication Date
CN1096029A CN1096029A (zh) 1994-12-07
CN1036009C true CN1036009C (zh) 1997-10-01

Family

ID=9437257

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93121519A Expired - Fee Related CN1036009C (zh) 1992-12-30 1993-12-29 2-噻吩基咪唑并[2，1-b]苯并噻唑-3-乙酸衍生物，其制备方法及其药用

Country Status (18)

Country Link
US (1) US5418248A (cg-RX-API-DMAC7.html)
EP (1) EP0605295A1 (cg-RX-API-DMAC7.html)
JP (1) JPH06234770A (cg-RX-API-DMAC7.html)
KR (1) KR0140846B1 (cg-RX-API-DMAC7.html)
CN (1) CN1036009C (cg-RX-API-DMAC7.html)
AU (1) AU666790B2 (cg-RX-API-DMAC7.html)
CA (1) CA2112555A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ282959B6 (cg-RX-API-DMAC7.html)
FI (1) FI935915L (cg-RX-API-DMAC7.html)
FR (1) FR2699921B1 (cg-RX-API-DMAC7.html)
HU (1) HUT70409A (cg-RX-API-DMAC7.html)
IL (1) IL108225A (cg-RX-API-DMAC7.html)
NO (1) NO934881L (cg-RX-API-DMAC7.html)
NZ (1) NZ250579A (cg-RX-API-DMAC7.html)
PL (1) PL301680A1 (cg-RX-API-DMAC7.html)
SK (1) SK149393A3 (cg-RX-API-DMAC7.html)
TW (1) TW257764B (cg-RX-API-DMAC7.html)
ZA (1) ZA939760B (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3783497A (en) * 1996-08-09 1998-03-06 Yamanouchi Pharmaceutical Co., Ltd. Metabotropic glutamate receptor agonists
EP2218464A1 (en) * 2009-02-11 2010-08-18 Technische Universität München Compounds for non-invasive measurement of aggregates of amyloid peptides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895863A (en) * 1987-10-20 1990-01-23 Roussel Uclaf Novel imidazo[2,1-B]benzothiazoles
US4968708A (en) * 1988-06-22 1990-11-06 Nikken Chemicals Co., Ltd. Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4896863A (en) * 1988-05-26 1990-01-30 Tim Riplinger System having material dispensing and wind up device with guide
EP0524055A1 (fr) * 1991-07-19 1993-01-20 Synthelabo Dérivés d'imidazo[2,1-b]benzothiazole-3-acétamide, leur préparation et leur application en thérapeutique
DE69325167T2 (de) * 1992-03-12 2000-01-20 Smithkline Beecham P.L.C., Brentford Kondensierte indol-derivate als 5-ht4-rezeptor-antagonisten

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895863A (en) * 1987-10-20 1990-01-23 Roussel Uclaf Novel imidazo[2,1-B]benzothiazoles
US4968708A (en) * 1988-06-22 1990-11-06 Nikken Chemicals Co., Ltd. Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same

Also Published As

Publication number Publication date
KR0140846B1 (ko) 1998-06-15
JPH06234770A (ja) 1994-08-23
CN1096029A (zh) 1994-12-07
SK149393A3 (en) 1995-02-08
FI935915A7 (fi) 1994-07-01
NO934881D0 (no) 1993-12-29
FI935915L (fi) 1994-07-01
NO934881L (no) 1994-07-01
CZ291893A3 (en) 1994-07-13
KR940014415A (ko) 1994-07-18
HUT70409A (en) 1995-10-30
HU9303785D0 (en) 1994-04-28
CA2112555A1 (en) 1994-07-01
FR2699921B1 (fr) 1995-02-10
EP0605295A1 (fr) 1994-07-06
FI935915A0 (fi) 1993-12-29
IL108225A (en) 1997-04-15
ZA939760B (en) 1994-08-18
TW257764B (cg-RX-API-DMAC7.html) 1995-09-21
CZ282959B6 (cs) 1997-11-12
AU5276293A (en) 1994-07-14
US5418248A (en) 1995-05-23
FR2699921A1 (fr) 1994-07-01
PL301680A1 (en) 1994-07-11
NZ250579A (en) 1995-07-26
IL108225A0 (en) 1994-04-12
AU666790B2 (en) 1996-02-22

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