CN103495140A - Preparation method for traditional Chinese medicament extract for regulating qi and resolving phlegm - Google Patents
Preparation method for traditional Chinese medicament extract for regulating qi and resolving phlegm Download PDFInfo
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Abstract
The invention discloses a preparation method for a traditional Chinese medicament extract for regulating qi and resolving phlegm. The preparation method comprises the following steps: performing water-extraction on the raw materials of liquorice, curcuma aromatica and calcined phlogopitum for 2 to 3 times; combining extract solutions; performing after-treatment to obtain a concentrated solution A; dissolving the raw materials of compound of glauber-salt and liquorice, borax, alum, bamboo cream and ginger juice with 5 times amount of water, and screening the solution by a 100-mesh sieve to obtain a solution B; mixing the concentrated solution A and the solution B; drying the mixed solution under reduced pressure to obtain a dried material; mixing the dried material with medicinal accessories to prepare an oral preparation. Pharmacological experiment results show that the extract disclosed by the invention has a better effect on removing phlegm compared with the original preparation with the same dose. The traditional Chinese medicament extract for regulating qi and resolving phlegm obtained by the preparation method disclosed by the invention has the characteristics that the quality is stable and controllable, the dose of a patient is reduced, the bioavailability is improved, and the treatment effect is improved. The preparation prepared by the method disclosed by the invention is approved by the majority of patients, and has remarkable economical benefits and social benefits.
Description
Technical field
The invention belongs to modernization of Chinese medicine technical field, relate to a kind of preparation method of the pleasant Chinese medicine extract that reduces phlegm.
Background technology
The dispelling pathogenic wind and eliminating phlegm ball is the current commercially available a kind of pleasant Chinese medicine reduced phlegm, and it is made by Radix Glycyrrhizae, Matrii Sulfas Exsiccatus, Radix Curcumae, Borax, Lapis Micae Aureus (forging), Alumen, Cinnabaris, bamboo trickle paste, Rhizoma Zingiberis Recens juice, Borneolum Syntheticum, Mentholum.The dispelling pathogenic wind and eliminating phlegm ball can pleasantly reduce phlegm, be mainly used in expectorant stop up gas-tight, mad epilepsy, speaking incoherently, in silence, chest and diaphragm is unfavorable for coma, dizziness tinnitus, asthma and cough.In side, Borax, Lapis Micae Aureus, Alumen reduce phlegm; The Radix Curcumae promoting QI circulation for relieving depression, removing heat from blood clears away heart-fire; The Matrii Sulfas Exsiccatus heat-clearing and toxic substances removing; Bamboo trickle paste, Rhizoma Zingiberis Recens juice clear away heart-fire and eliminate the phlegm; Cinnabaris, Herba Menthae, Borneolum Syntheticum heat clearing away, tranquillizing the mind by relieving convulsion; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, have again the merit of removing toxic substances, and all medicines share, and play altogether pleasant merit of reducing phlegm.Clinically be mainly used in expectorant to stop up the diseases such as gas-tight mad, unrest, coma more applicable.
The prescription of dispelling pathogenic wind and eliminating phlegm ball and method for making are: Radix Glycyrrhizae 200g, Matrii Sulfas Exsiccatus 100g, Radix Curcumae 200g, Borax 50g, Lapis Micae Aureus (forging) 50g, Alumen 40g, Cinnabaris 15g, bamboo trickle paste 20g, Rhizoma Zingiberis Recens juice 15g, Borneolum Syntheticum 4g, Mentholum 4g.Above ten medical materials simply, except Mentholum, bamboo trickle paste, Rhizoma Zingiberis Recens juice, Cinnabaris water flies or is ground into impalpable powder, the Borneolum Syntheticum porphyrize, the Six-elements such as all the other Radix Glycyrrhizaes are ground into coarse powder, with bamboo trickle paste, Rhizoma Zingiberis Recens juice, mix thoroughly, dry, pulverize into fine powder, with Cinnabaris, Borneolum Syntheticum and Mentholum facing-up, sieve, mix.Every 100g powder adds refined honey 65～75g and makes big honeyed pills, obtains.
The former prescription type of this medicine is honeyed pill, easily goes mouldy and microbiological contamination.Take and carry inconvenience, mouthfeel is not good, the heavy 4.5g of every ball, and children's, old man and pharyngolaryngitis patient dysphagia, take inconvenience, and patient's acceptance level is poor.And from oral slow to the gastrointestinal absorption process.These factors directly affect dispelling pathogenic wind and eliminating phlegm ball applying clinically.
Summary of the invention
The purpose of this invention is to provide a kind of pleasant Chinese medicine composition preparation method of reducing phlegm.For realizing this purpose, the present invention by the following technical solutions:
A kind of preparation method of the pleasant Chinese medicine extract that reduces phlegm is characterized in that being undertaken by following step:
(1) take each raw material by 4 parts, 200 parts, Radix Glycyrrhizae, 100 parts of Matrii Sulfas Exsiccatus, 200 parts of Radix Curcumaes, 50 parts of Boraxs, 50 parts of Lapis Micae Aureuses (forging), 40 parts of Alumens, 15 parts, Cinnabaris, 20 parts of bamboo trickle pastes, 15 parts of Rhizoma Zingiberis Recens juice, 4 parts of Borneolum Syntheticums, Mentholum;
(2) by Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus (forging) three flavor raw material water extraction 2-3 time, at every turn with 8-12 times of water gaging extraction 1-2 hour, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.03-1.10, obtains concentrated solution A;
(3) Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B;
(4) concentrated solution A and solution B are mixed, drying under reduced pressure or spray drying, obtain dry thing;
(5) the dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, with the acceptable pharmaceutic adjuvant mf mass pil of pharmaceutics, tablet, granule, capsule.
The preparation method of the preferred pleasant Chinese medicine extract that reduces phlegm of the present invention, adopt following method to prepare: by proportioning raw materials, to take each raw material; By Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus (forging) three flavor raw material water extraction 2 times, with 10 times of water gagings, extract 1 hour at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.03-1.08, obtains concentrated solution A; Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B; Concentrated solution A and solution B are mixed, and drying under reduced pressure or spray drying, obtain dry thing; The dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, with the acceptable pharmaceutic adjuvant mf mass pil of pharmaceutics, tablet, granule, capsule.
The acceptable pharmaceutic adjuvant of pharmaceutics of the present invention is selected from any one or a few in starch, microcrystalline Cellulose, sucrose, aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, sodium carboxymethyl cellulose, crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and sodium sulfite.
The Chinese medicine composition that technical solution of the present invention is related and preparation thereof all have good pleasant resolve phlegm effect.Can be used for treating the expectorant heap soil or fertilizer over and around the roots gas-tight, mad epilepsy, speaking incoherently, in silence, chest and diaphragm is unfavorable for coma, dizziness tinnitus, asthma and cough.By zoopery, we unexpectedly find, pharmaceutical composition prepared by technique of the present invention is compared with former dosage form, has excellent phlegm-dispelling functions.
The good effect that the pleasant Chinese medicine composition preparation method of reducing phlegm disclosed by the invention compared with prior art had is: the present invention uses theory of Chinese medical science analysis prescription to form, according to the physicochemical property of each flavour of a drug ingredient and the result of study of pharmacological action, research has obtained the preparation method of reasonable, stable active component.Adopt technical solution of the present invention, prepared pharmaceutical preparation stable and controllable for quality, that curative effect is compared with existing commercially available dosage form and significantly improved, patient's taking dose reduces, bioavailability improves, there is significant economic and social benefit.
The specific embodiment
After the preferred embodiment described in detail, being familiar with this technology personage can be well understood to, can carry out various variations and modification not breaking away under above-mentioned claim and spirit, any simple modification, equivalent variations and modification that all foundations technical spirit of the present invention is done above embodiment, all belong to the scope of technical solution of the present invention.And the present invention also is not subject to the restriction of example embodiment in description.Various traditional Chinese medicinal material raw materials of the present invention all has commercially available.
Embodiment 1:
Prepare Chinese medicine extract
One. prescription: Radix Glycyrrhizae 2000g, Matrii Sulfas Exsiccatus 1000g, Radix Curcumae 2000g, Borax 500g, Lapis Micae Aureus (forging) 500g, Alumen 400g, Cinnabaris 150g, bamboo trickle paste 200g, Rhizoma Zingiberis Recens juice 150g, Borneolum Syntheticum 40g, Mentholum 40g
Two. method for making:
Take each raw material by proportioning raw materials, standby; By Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus (forging) three flavor raw material water extraction 2 times, with 10 times of water gagings, extract 1 hour at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.05, obtains concentrated solution A; Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B; Concentrated solution A and solution B are mixed, and drying under reduced pressure or spray drying, obtain dry thing; The dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, obtain active constituents of medicine 3230 grams.
Embodiment 2:
Prepare Chinese medicine extract
One. prescription: Radix Glycyrrhizae 2000g, Matrii Sulfas Exsiccatus 1000g, Radix Curcumae 2000g, Borax 500g, Lapis Micae Aureus (forging) 500g, Alumen 400g, Cinnabaris 150g, bamboo trickle paste 200g, Rhizoma Zingiberis Recens juice 150g, Borneolum Syntheticum 40g, Mentholum 40g
Two. method for making:
Take each raw material by proportioning raw materials, standby; By 12 times of amounts, the 10 times of water gagings extractions for raw material of Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus (forging) three flavors, extract 2 hours at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.10, obtains concentrated solution A; Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B; Concentrated solution A and solution B are mixed, and drying under reduced pressure or spray drying, obtain dry thing; The dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, obtain active constituents of medicine 3300 grams.
Embodiment 3:
Prepare Chinese medicine extract
One. prescription: Radix Glycyrrhizae 200g, Matrii Sulfas Exsiccatus 100g, Radix Curcumae 200g, Borax 50g, Lapis Micae Aureus (forging) 50g, Alumen 40g, Cinnabaris 15g, bamboo trickle paste 20g, Rhizoma Zingiberis Recens juice 15g, Borneolum Syntheticum 4g, Mentholum 4g
Two. method for making:
Take each raw material by proportioning raw materials, standby; By 8 times of amounts, the 10 times of water gagings extractions for raw material of Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus (forging) three flavors, extract 2 hours at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.03, obtains concentrated solution A; Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B; Concentrated solution A and solution B are mixed, and drying under reduced pressure or spray drying, obtain dry thing; The dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, obtain active constituents of medicine 333 grams.
Embodiment 4:
Prepare Chinese medicine extract
One. prescription: Radix Glycyrrhizae 200g, Matrii Sulfas Exsiccatus 100g, Radix Curcumae 200g, Borax 50g, Lapis Micae Aureus (forging) 50g, Alumen 40g, Cinnabaris 15g, bamboo trickle paste 20g, Rhizoma Zingiberis Recens juice 15g, Borneolum Syntheticum 4g, Mentholum 4g
Two. method for making:
Take each raw material by proportioning raw materials, standby; By 8 times of amounts, 10 times of amounts, the 12 times of water gagings extractions for raw material of Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus (forging) three flavors, extract 1 hour at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.08, obtains concentrated solution A; Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B; Concentrated solution A and solution B are mixed, and drying under reduced pressure or spray drying, obtain dry thing; The dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, obtain active constituents of medicine 350 grams.
Embodiment 5: prepare tablet
The active component 300g that embodiment 1 obtains, add dextrin 200g, sucrose 80g, and magnesium stearate 0.9g, tabletting, obtain tablet, and every is 0.4g.
Embodiment 6: prepare granule
The active component 500g that embodiment 2 obtains, add dextrin 100g, xylitol 400g, and citric acid 1g, aspartame 1g granulates, and obtains granule, and every bag is 2.5g.
Embodiment 7:
Zoopery one: the impact of extract of the present invention on the mice phlegm-dispelling functions
One. materials and methods
(lot number: 130103), in Tianjin, newly Pharmaceutical limited company reaches the production of core hall pharmaceutical factory to the dispelling pathogenic wind and eliminating phlegm ball
Animal: the ICR mice is provided by Beijing Vital River Experimental Animals Technology Co., Ltd..
Ammonium chloride (lot number: 20120128), dragon Xinghua, Asia-Pacific, Tianjin work company limited
Phenol red (lot number: 20121129), rich Dihua, Tianjin work company limited
UV7504 ultraviolet-uisible spectrophotometer: Shanghai precision instrument company limited
Get 60 of healthy ICR mices, body weight 18-22g, be divided at random 5 groups, be blank group, ammonium chloride positive controls (0.5g/kg), dispelling pathogenic wind and eliminating phlegm extract of bolus (press embodiment 1 method preparation) is low, high dose group (1.6,3.2g crude drug/kg), dispelling pathogenic wind and eliminating phlegm ball group (1.6g crude drug/kg), give isopyknic pure water except blank group, other administration groups are all by the continuous gastric infusion of above-mentioned dosage 7 days, and the administration volume is 20ml/kg.Fasting 12h before the last administration, 0.5 hour phenol red normal saline solution 10ml/kg of lumbar injection 5% after the last administration, 0.5 after hour, disconnected neck is put to death mice, peel off the trachea surrounding tissue, cut from the thyroid cartilage to one section trachea of trachea bifurcation, put into the test tube that fills alkaline normal saline (normal saline 2ml+1N sodium hydroxide 0.1ml) solution, after room temperature is placed 2 hours, the trachea eluent is surveyed to its absorbance with ultraviolet-uisible spectrophotometer in 546nm wavelength place, by phenol red standard curve, calculate every phenol red content of mice trachea.Experimental data is added up with variance analysis.
Two. result: in Table 1.
The table 1 extract administration impact on the mice phlegm-dispelling functions in seven days (
)
| Group | Number of animals (only) | Dosage (g crude drug/kg) | Phenol red concentration (ug/ml) |
| Blank group | 12 | —— | 1.53±0.24 |
| The ammonium chloride group | 12 | 0.5 | 2.88±0.91** |
| Dispelling pathogenic wind and eliminating phlegm extract of bolus low dose group | 12 | 1.6 | 2.64±0.25**# |
| Dispelling pathogenic wind and eliminating phlegm extract of bolus high dose group | 12 | 3.2 | 2.97±0.71** |
| Dispelling pathogenic wind and eliminating phlegm ball group | 12 | 1.6 | 2.24±0.66* |
Compare * P<0.05 with the blank group, * * P<0.01 with dispelling pathogenic wind and eliminating phlegm ball group than # P<0.05
Result shows: the dispelling pathogenic wind and eliminating phlegm extract of bolus is low, high dose group and blank group relatively, utmost point significant difference (P<0.01) is all arranged, point out this extract can obviously promote the phenol red excretion amount of mice trachea, and present certain dose-effect relationship, illustrate that this invention extract has good phlegm-dispelling functions.Under Isodose, the dispelling pathogenic wind and eliminating phlegm extract of bolus compares with former dosage form under Isodose, and significant difference (P<0.05) is arranged, and points out extract phlegm-dispelling functions of the present invention to be better than former dosage form.
Claims (3)
1. the preparation method of the pleasant Chinese medicine extract that reduces phlegm is characterized in that being undertaken by following step:
(1) by 200 parts, Radix Glycyrrhizae, 100 parts of Matrii Sulfas Exsiccatus, 200 parts of Radix Curcumaes, 50 parts of Boraxs, forge 4 parts of 50 parts of Lapis Micae Aureuses, 40 parts of Alumens, 15 parts, Cinnabaris, 20 parts of bamboo trickle pastes, 15 parts of Rhizoma Zingiberis Recens juice, 4 parts of Borneolum Syntheticums, Mentholum and take each raw material;
(2) Radix Glycyrrhizae, Radix Curcumae, Lapis Micae Aureus are forged to three flavor raw material water extractions 2-3 time, extracted 1-2 hour with 8-12 times of water gaging at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.03-1.10, obtains concentrated solution A;
(3) Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B;
(4) concentrated solution A and solution B are mixed, drying under reduced pressure or spray drying, obtain dry thing;
(5) the dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, with the acceptable pharmaceutic adjuvant mf mass pil of pharmaceutics, tablet, capsule, granule.
2. preparation method claimed in claim 1, wherein the pleasant Chinese medicine extract that reduces phlegm adopts following method to prepare: by proportioning raw materials, take each raw material; By Radix Glycyrrhizae, Radix Curcumae, forge Lapis Micae Aureus three flavor raw material water extraction 2 times, with 10 times of water gagings, extract 1 hour at every turn, merge extractive liquid,, being concentrated into relative density under 50-60 ℃ of condition is 1.03-1.08, obtains concentrated solution A; Matrii Sulfas Exsiccatus, Borax, Alumen, bamboo trickle paste, Rhizoma Zingiberis Recens juice five tastes raw material are dissolved with 5 times of water gagings, cross 100 mesh sieves, obtain solution B; Concentrated solution A and solution B are mixed, and drying under reduced pressure or spray drying, obtain dry thing; The dry thing obtained is ground into to fine powder, flies or be ground into the Cinnabaris of impalpable powder, Borneolum Syntheticum and the Mentholum facing-up of porphyrize with water, with the acceptable pharmaceutic adjuvant mf mass pil of pharmaceutics, tablet, capsule.
3. the preparation method of the described Chinese medicine extract of claim 1-2 any one, the acceptable pharmaceutic adjuvant of wherein said pharmaceutics is selected from any one or a few in starch, microcrystalline Cellulose, sucrose, aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, sodium carboxymethyl cellulose, crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and sodium sulfite.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258143A (en) * | 2014-09-29 | 2015-01-07 | 章财华 | Traditional Chinese medicine for treating depressive psychosis caused by vital energy and phlegm stagnation |
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2013
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Non-Patent Citations (2)
| Title |
|---|
| 张兆旺: "《中药药剂学》", 31 January 2003, 中国中医药出版社 * |
| 胡永盛，等: "《新编中成药》", 31 May 1987, 吉林科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258143A (en) * | 2014-09-29 | 2015-01-07 | 章财华 | Traditional Chinese medicine for treating depressive psychosis caused by vital energy and phlegm stagnation |
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Application publication date: 20140108 |