CN103487592A - Vaginal secretion analysis system - Google Patents

Vaginal secretion analysis system Download PDF

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Publication number
CN103487592A
CN103487592A CN201210193789.8A CN201210193789A CN103487592A CN 103487592 A CN103487592 A CN 103487592A CN 201210193789 A CN201210193789 A CN 201210193789A CN 103487592 A CN103487592 A CN 103487592A
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detection unit
vaginal fluid
sample
vaginal
analytic system
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CN201210193789.8A
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CN103487592B (en
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王加义
王淳玉
张永威
孙滨
赵玉林
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BEIJING ZHONGSHENG JINYU DIAGNOSIS TECHNOLOGY CO., LTD.
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BEIJING ZHONGSHENG JINYU DIAGNOSIS TECHNOLOGY Co Ltd
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Abstract

The invention discloses a vaginal secretion analysis system. The system includes a morphological detection unit for detecting formed elements of vaginal secretions, a biochemical detection unit for biochemical detection of the vaginal secretions, a human-computer interaction device for data interaction with a data processing unit, and the data processing unit for processing data obtained through the morphological detection unit, the biochemical detection unit and the human-computer interaction device to obtain analysis results of the vaginal secretions. The vaginal secretions are subjected to a morphological microscopic examination, and synchronous detection and synchronous analysis of pre-produced enzyme spectra and metabolite spectra of normal bacteria and pathogenic bacteria, so that morphological results and biochemical results are combined and supplemented with each other, and thus misdiagnosis, such as a missed diagnosis, caused by no completeness, no comprehension and no systematicness of only consideration of the physics or biochemical test results is avoided. The vaginal secretion analysis system can accurately evaluate the vaginal micro ecology, and finds out all common vaginitis and vaginal infection pathogenic microorganisms.

Description

The vaginal fluid analytic system
Technical field
The present invention relates to clinical medicine inspection technology field, relate in particular to a kind of vaginal fluid analytic system.
Background technology
At present, vagina infection control is faced with the low and high problem of recurrence rate of cure rate clinically, and the main cause that causes this phenomenon is usually be eager treatment and at first determine pathogenic microorganism of clinician, and this is the modal reason that causes treating unsuccessfully.
Vaginal fluid conventional sense (be called for short leukorrhea routine) is a widely used important medical inspection project clinically at present, and the method for carrying out clinically the vaginal fluid conventional sense is divided into two classes:
The first kind is to utilize microscopical morphology humidity strip Microscopical Method For Detection, can directly observe the visible component situation of vaginal fluid, find miscellaneous bacteria and epithelial cell and the leucocyte pyocytes such as vaginal fluid normal bacteria, trichomonad, fungi, but can not find the bacteria resistance function of normal dominant bacteria, can't distinguish the pathogenic of miscellaneous bacteria and be aerobic bacteria or anaerobion, also can't differentiate the pathogenic etc. of fungi.
Another kind of is to utilize biochemical method to carry out the dry chemical detection to vaginal fluid, the indexs such as the main preformation enzyme by the normal dominant bacteria of detection and pathogenic bacteria and metabolin, the function assessment situation that can reflect vagina normal bacteria and pathogenic bacteria, but the method is poor to trichomonad, fungi assay reliability, specificity is also poor, can't reflect cleanliness, and because artificial interpretation subjectivity is strong, workload is large, can affect detection speed.
At present, mostly clinically is to carry out the detection of vaginal fluid with a kind of method, and the result of detection is system, not comprehensive not, easily causes mistaken diagnosis and fails to pinpoint a disease in diagnosis, and is unfavorable for clinical treatment.
In sum, existing vaginal fluid detection system exists detection efficiency low, the problems such as the poor reliability of testing result.
Summary of the invention
(1) technical matters that will solve
The technical problem to be solved in the present invention is: how the visible component of vaginal fluid is detected and combines with biochemistry detection, structure considers the vaginal fluid analytic system of visible component analysis result and biochemical studies, to increase the reliability of testing result, improve detection efficiency.
(2) technical scheme
For addressing the above problem, the invention provides a kind of vaginal fluid analytic system, comprising:
The morphologic detection unit, detected for the visible component to vaginal fluid;
The biochemistry detection unit, detected for preformation enzyme and metabolin to vaginal fluid;
Human-computer interaction device, for carrying out data interaction with data processing unit;
Data processing unit, process and obtain the vaginal fluid analysis result for the data to obtaining by morphologic detection unit, biochemistry detection unit and human-computer interaction device.
In aforesaid vaginal fluid analytic system, described physical detection unit comprises: objective table, microscope and CCD, described CCD is for sending gathered image to data processing unit.
In aforesaid vaginal fluid analytic system, described biochemistry detection unit comprises:
The color detection module, for realizing the color measuring to testing sample;
Touch display screen, for realizing the man-machine interaction of testing process;
Heating arrangement, for being offering sample stationary temperature heating environment in testing process;
The automatic control panel that comprises single-chip microcomputer and industrial computer, wherein, described single-chip microcomputer is for realizing the control to the biochemistry detection unit, described industrial computer is for realizing man-machine interface and man-machine interaction;
External scanner, for scanning the bar code information of sample to be tested.
In aforesaid vaginal fluid analytic system, described biochemistry detection unit also comprises: for the automatically feed feeding mechanism of realizing sample to be tested, for the connecting gear that transmits sample to be tested with for the sample arm mechanism of test process automatic ration application of sample.
In aforesaid vaginal fluid analytic system, described biochemistry detection unit also comprises printer, for printing testing result.
In aforesaid vaginal fluid analytic system, described color detection module comprises color sensor, lens, LED, reaches ray machine head mechanism.
In aforesaid vaginal fluid analytic system, described heating arrangement comprises: heating plate, temperature controller, solid-state relay, temperature sensor.
In aforesaid vaginal fluid analytic system, described touch display screen is comprised of liquid crystal display and touch-screen.
(3) beneficial effect
The present invention is by synchronous detection and the Synchronization Analysis of vaginal fluid morphology microscopy and normal bacteria, pathogenic bacteria preformation zymogram, metabolite profile, morphology result and chemical result are mutually combined supplementary, avoided manually-operated subjectivity, and only consider physics or biochemistry detection result imperfect, not comprehensively, not systemic, cause clinical misdiagnosis and the problem such as fail to pinpoint a disease in diagnosis.The present invention can the accurate evaluation microecology in vaginas, finds the pathogenic microorganisms of common vagina infection; And the relative traditional detection device of system of the present invention has simple to operate, goes out analysis report advantage fast, can provide more complete analysis result to the clinician, has greatly improved clinic diagnosis efficiency.
The accompanying drawing explanation
The structural representation that Fig. 1 is vaginal fluid analytic system described in embodiment of the present invention;
The side view that Fig. 2 is biochemistry detection unit described in the embodiment of the present invention 2;
The vertical view that Fig. 3 is biochemistry detection unit described in the embodiment of the present invention 2;
The structural representation that Fig. 4 is biochemistry detection unit described in the embodiment of the present invention 1.
Embodiment
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following examples are used for the present invention is described, but are not used for limiting the scope of the invention.
Embodiment 1: as shown in Fig. 1,4, vaginal fluid analytic system of the present invention comprises:
Morphologic detection unit 1, detected for the visible component to vaginal fluid;
Biochemistry detection unit 2, detected for preformation enzyme and metabolin to vaginal fluid;
Human-computer interaction device 3, for carrying out data interaction with data processing unit 4;
Data processing unit 4, process and obtain the vaginal fluid analysis result for the data to obtaining by physical detection unit 1, biochemistry detection unit 2 and human-computer interaction device 3.
Described physical detection unit comprises: objective table 5, microscope 6 and CCD7, described CCD7 is for sending gathered image to data processing unit 4.
Described biochemistry detection unit 2 comprises:
Color detection module 8, for realizing the color measuring to testing sample;
Touch display screen 9, for realizing the man-machine interaction of testing process;
Heating arrangement 10, for being offering sample stationary temperature heating environment in testing process;
The automatic control panel 11 that comprises single-chip microcomputer and industrial computer, wherein, described single-chip microcomputer is for realizing the control to the biochemistry detection unit, described industrial computer is for realizing man-machine interface and man-machine interaction;
External scanner 12, for scanning the bar code information of sample to be tested.
Described biochemistry detection unit 2 also comprises printer 16, for printing testing result.
Described color detection module comprises color sensor, lens, LED, reaches ray machine head mechanism.
Described heating arrangement comprises: heating plate, temperature controller, solid-state relay, temperature sensor.
Described touch display screen is comprised of liquid crystal display and touch-screen.
Embodiment 2: as Figure 1-3, the present embodiment as different from Example 1: the biochemistry detection unit 2 in the present embodiment also comprises: for the automatically feed feeding mechanism 13 of realizing sample to be tested, for the connecting gear 14 that transmits sample to be tested with for the sample arm mechanism 15 of test process automatic ration application of sample.
The course of work of the present embodiment mesophytization detecting unit 2:
After bar code information with external scanner 12 scanning samples to be tested, input relevant information on touch display screen 9, after having inputted, sample to be tested is put into to the porch of feeding mechanism 13, the optocoupler of porch detects sample and puts in place after signal, feeding mechanism 13 automatic feeds, after charging completes, connecting gear 14 starts to transmit inward, and sample arm mechanism 15 starts imbibition, when sample is transported to the application of sample position, sample arm mechanism 15 starts application of sample.After application of sample completes, connecting gear 14 continues to transmit, when sample to be tested is transported to detection position, and the detection for the first time of 8 pairs of samples to be tested of color detection module, after having detected, sample to be tested enters flat-temperature zone and is heated by heating arrangement 10.After within 10 minutes, having heated, by 15 pairs of samples to be tested of sample arm mechanism, carry out application of sample for the second time, application of sample completes, and after waiting for 3 minutes, by 8 pairs of samples to be tested of color detection module, carries out color detection for the second time.After detection completes, printer 16 is printed testing result, simultaneously, by network interface, testing result is transferred to data processing unit 4.
The course of work of embodiment 1 mesophytization detecting unit is compared with the present embodiment, and its difference is manually to complete the functions such as application of sample, charging.
The course of work of morphologic detection unit in the present embodiment:
After the bar code information of external scanner 12 scanned samples, sample to be tested is put on the objective table 5 of microscope 6, data processing unit 4 is controlled the stepper motor of X, Y-direction on microscope 6, realize the motion of sample, data processing unit 4 gathers the sample image of CCD7, carry out in real time analyzing and processing, analyze the shape facility of visible component in vaginal fluid and calculate the ratio of each visible component.
Embodiment 3: a kind of method of utilizing aforementioned system to carry out the vaginal fluid analysis comprises the following steps:
Color, proterties and the smell of morphologic detection unit inspection vaginal fluid, the form of normal bacteria, epithelial cell, miscellaneous bacteria, pathogenic microorganisms and leucocyte or pyocyte, quantity;
The biochemical function feature of normal bacteria, miscellaneous bacteria and the pathogenic microorganisms of biochemistry detection unit inspection vaginal fluid;
The data processing unit comprehensive morphological is learned the testing result of detecting unit and biochemistry detection unit, and the information analysis of human-computer interaction device input draws the vagina infection situation.
The visible component information of vaginal fluid comprises: the physics indexs such as the color of vaginal fluid, proterties, smell; The indexs such as normal bacteria quantity, form; The index such as cellular morphology, quantity; The indexs such as leucocyte or pyocyte form, quantity; The indexs such as various miscellaneous bacteria forms, quantity; Other microorganisms, as biochemistry detection information such as fungi, trichomonad, mycoplasma, Chlamydia, HPV viruses, comprise the indexs such as preformation zymogram metabolite profile that reflect normal bacteria, pathogenic bacteria drug resistance and functional character.After analysis completes, after inputting relevant information by human-computer interaction device, gather the biochemical analysis result of vaginal fluid, the information of human-computer interaction device typing and all results that visible component is analyzed by data processing unit, the biochemical indicators such as vaginal fluid visible component and normal bacteria, pathogenic bacteria preformation zymogram, metabolite profile are carried out to the analysis-by-synthesis evaluation, provide evaluation result, and formation diagnosis report, directly print result and outputing in the infosystem of hospital.
Vaginal fluid analytic system of the present invention is based on the permutation and combination of vaginal fluid proterties, biochemistry and morphology aspect, in conjunction with mode multifactor, multilevel, weighted ratio carry out assay, the method is for pioneering up to now; Native system has been realized the standardization of test item, the property recognized each other that has increased measurement result and reliability by the unification to test item and detection index.
Above embodiment is only for illustrating the present invention; and be not limitation of the present invention; the those of ordinary skill in relevant technologies field; without departing from the spirit and scope of the present invention; can also make a variety of changes and modification; therefore all technical schemes that are equal to also belong to category of the present invention, and scope of patent protection of the present invention should be defined by the claims.

Claims (8)

1. a vaginal fluid analytic system, is characterized in that, comprising:
Morphologic detection unit (1), detected for the visible component to vaginal fluid;
Biochemistry detection unit (2), detected for preformation enzyme and metabolin to vaginal fluid;
Human-computer interaction device (3), for carrying out data interaction with data processing unit;
Data processing unit (4), process and obtain the vaginal fluid analysis result for the data to obtaining by morphologic detection unit (1), biochemistry detection unit (2) and human-computer interaction device (3).
2. vaginal fluid analytic system as claimed in claim 1, it is characterized in that, described morphologic detection unit (1) comprising: objective table (5), microscope (6) and CCD (7), described CCD (7) sends data processing unit (4) to for the image gathered.
3. vaginal fluid analytic system as claimed in claim 1, is characterized in that, described biochemistry detection unit (2) comprising:
Color detection module (8), for realizing the color measuring to testing sample;
Touch display screen (9), for realizing the man-machine interaction of testing process;
Heating arrangement (10), for being offering sample stationary temperature heating environment in testing process;
The automatic control panel (11) that comprises single-chip microcomputer and industrial computer, wherein, described single-chip microcomputer is for realizing the control to biochemistry detection unit (2), described industrial computer is for realizing man-machine interface and man-machine interaction;
External scanner (12), for scanning the bar code information of sample to be tested.
4. vaginal fluid analytic system as claimed in claim 3, it is characterized in that, described biochemistry detection unit (2) also comprises: for the automatically feed feeding mechanism (13) of realizing sample to be tested, for the connecting gear (14) that transmits sample to be tested with for the sample arm mechanism (15) of test process automatic ration application of sample.
5. vaginal fluid analytic system as described as claim 3 or 4, is characterized in that, described biochemistry detection unit (2) also comprises printer (16), for printing testing result.
6. vaginal fluid analytic system as claimed in claim 1, is characterized in that, described color detection module (8) comprises color sensor, lens, LED, reaches ray machine head mechanism.
7. vaginal fluid analytic system as claimed in claim 1, is characterized in that, described heating arrangement (9) comprising: heating plate, temperature controller, solid-state relay, temperature sensor.
8. vaginal fluid analytic system as claimed in claim 1, is characterized in that, described touch display screen (10) is comprised of liquid crystal display and touch-screen.
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Cited By (7)

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CN103823049A (en) * 2014-02-27 2014-05-28 科宝智慧医疗科技(上海)有限公司 Analyzer of visible component of body fluid
CN105372439A (en) * 2015-12-01 2016-03-02 江苏硕世生物科技有限公司 Female reproductive tract microecology evaluation and detection system
CN110133312A (en) * 2019-06-14 2019-08-16 瓜藤科技(深圳)有限公司 Vaginal fluid detection device and method
CN111458493A (en) * 2019-01-22 2020-07-28 北京中生金域诊断技术股份有限公司 Multifunctional biochemical analyzer
CN114088508A (en) * 2021-11-24 2022-02-25 平顶山市计划生育科学技术研究所 Detection system for female reproduction
CN114112619A (en) * 2021-11-24 2022-03-01 平顶山市计划生育科学技术研究所 Detection method for female reproduction
CN114966072A (en) * 2022-08-02 2022-08-30 深圳市瑞图生物技术有限公司 Gynecological sample analyzer and gynecological sample analysis method

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Cited By (12)

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CN103823049A (en) * 2014-02-27 2014-05-28 科宝智慧医疗科技(上海)有限公司 Analyzer of visible component of body fluid
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CN105372439A (en) * 2015-12-01 2016-03-02 江苏硕世生物科技有限公司 Female reproductive tract microecology evaluation and detection system
CN111458493A (en) * 2019-01-22 2020-07-28 北京中生金域诊断技术股份有限公司 Multifunctional biochemical analyzer
CN111458493B (en) * 2019-01-22 2024-04-12 北京中生金域诊断技术股份有限公司 Multifunctional biochemical analyzer
CN110133312A (en) * 2019-06-14 2019-08-16 瓜藤科技(深圳)有限公司 Vaginal fluid detection device and method
CN110133312B (en) * 2019-06-14 2024-01-12 瓜藤生物科技(深圳)有限公司 Vaginal secretion detection device and method
CN114088508A (en) * 2021-11-24 2022-02-25 平顶山市计划生育科学技术研究所 Detection system for female reproduction
CN114112619A (en) * 2021-11-24 2022-03-01 平顶山市计划生育科学技术研究所 Detection method for female reproduction
CN114112619B (en) * 2021-11-24 2024-03-29 平顶山市计划生育科学技术研究所 Female reproductive detection method
CN114966072A (en) * 2022-08-02 2022-08-30 深圳市瑞图生物技术有限公司 Gynecological sample analyzer and gynecological sample analysis method
CN114966072B (en) * 2022-08-02 2022-11-18 深圳市瑞图生物技术有限公司 Gynecological sample analyzer and gynecological sample analysis method

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Address after: 102200 No. 6, Spark Street, Changping District science and Technology Park, Beijing

Patentee after: BEIJING ZHONGSHENG JINYU DIAGNOSIS TECHNOLOGY CO., LTD.

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Patentee before: Beijing Zhongsheng Jinyu Diagnosis Technology Co., Ltd.