CN103443092B - 用作α7胆碱受体调节剂的吡咯衍生物 - Google Patents

用作α7胆碱受体调节剂的吡咯衍生物 Download PDF

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Publication number
CN103443092B
CN103443092B CN201280013694.1A CN201280013694A CN103443092B CN 103443092 B CN103443092 B CN 103443092B CN 201280013694 A CN201280013694 A CN 201280013694A CN 103443092 B CN103443092 B CN 103443092B
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methyl
pyrrol
benzenesulfonamide
propionyl
dimethyl
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CN103443092A (zh
Inventor
N·辛哈
G·贾纳
N·P·卡切
S·K·阿杜尔卡
G·D·哈特那普雷
V·P·帕列
R·K·卡姆博杰
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Lupin Ltd
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
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    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/47—Quinolines; Isoquinolines
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201280013694.1A 2011-02-03 2012-01-31 用作α7胆碱受体调节剂的吡咯衍生物 Expired - Fee Related CN103443092B (zh)

Applications Claiming Priority (3)

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IN151KO2011 2011-02-03
IN151/KOL/2011 2011-02-03
PCT/IB2012/050442 WO2012104782A1 (en) 2011-02-03 2012-01-31 Pyrrole derivatives used as modulators of alpha7 nachr

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CN103443092A CN103443092A (zh) 2013-12-11
CN103443092B true CN103443092B (zh) 2015-11-25

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US (1) US20130310419A1 (https=)
EP (1) EP2670744B1 (https=)
JP (1) JP5865397B2 (https=)
KR (1) KR20140041442A (https=)
CN (1) CN103443092B (https=)
AU (1) AU2012213086B2 (https=)
BR (1) BR112013019893A2 (https=)
CA (1) CA2825519A1 (https=)
MX (1) MX344701B (https=)
SG (1) SG192078A1 (https=)
WO (1) WO2012104782A1 (https=)

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