CN103442707A - 用于治疗胰腺炎的吉卡宾和衍生物 - Google Patents
用于治疗胰腺炎的吉卡宾和衍生物 Download PDFInfo
- Publication number
- CN103442707A CN103442707A CN2011800630388A CN201180063038A CN103442707A CN 103442707 A CN103442707 A CN 103442707A CN 2011800630388 A CN2011800630388 A CN 2011800630388A CN 201180063038 A CN201180063038 A CN 201180063038A CN 103442707 A CN103442707 A CN 103442707A
- Authority
- CN
- China
- Prior art keywords
- compound
- experimenter
- alkyl
- carbon
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (15)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710858297.9A CN107648210A (zh) | 2010-12-27 | 2011-12-22 | 用于治疗胰腺炎的吉卡宾和衍生物 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201061427236P | 2010-12-27 | 2010-12-27 | |
US61/427,236 | 2010-12-27 | ||
PCT/US2011/066736 WO2012092103A1 (en) | 2010-12-27 | 2011-12-22 | Gemcabene and derivatives for treating pancreatitis |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710858297.9A Division CN107648210A (zh) | 2010-12-27 | 2011-12-22 | 用于治疗胰腺炎的吉卡宾和衍生物 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN103442707A true CN103442707A (zh) | 2013-12-11 |
Family
ID=45498140
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2011800630388A Pending CN103442707A (zh) | 2010-12-27 | 2011-12-22 | 用于治疗胰腺炎的吉卡宾和衍生物 |
CN201710858297.9A Pending CN107648210A (zh) | 2010-12-27 | 2011-12-22 | 用于治疗胰腺炎的吉卡宾和衍生物 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710858297.9A Pending CN107648210A (zh) | 2010-12-27 | 2011-12-22 | 用于治疗胰腺炎的吉卡宾和衍生物 |
Country Status (14)
Country | Link |
---|---|
US (1) | US8846761B2 (zh) |
EP (2) | EP3170495B1 (zh) |
JP (3) | JP2014509305A (zh) |
CN (2) | CN103442707A (zh) |
AU (1) | AU2011352449B2 (zh) |
CA (1) | CA2822921C (zh) |
DK (1) | DK2658536T3 (zh) |
ES (1) | ES2608177T3 (zh) |
HK (1) | HK1250484A1 (zh) |
HU (1) | HUE031004T2 (zh) |
MX (1) | MX337593B (zh) |
PL (1) | PL2658536T3 (zh) |
PT (1) | PT2658536T (zh) |
WO (1) | WO2012092103A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2017118432A (ru) | 2014-11-14 | 2018-12-14 | Джемфир Терапьютикс Инк. | СПОСОБЫ И ПРОМЕЖУТОЧНЫЕ СОЕДИНЕНИЯ ДЛЯ ПОЛУЧЕНИЯ ДИАЛКАНОВЫХ ЭФИРОВ, СОДЕРЖАЩИХ КОНЦЕВУЮ α,ω-ДИКАРБОНОВОКИСЛОТНУЮ ГРУППУ |
KR20180073597A (ko) * | 2015-11-06 | 2018-07-02 | 젬파이어 세러퓨틱스 인코포레이티드 | 혼합 이상지질혈증의 치료 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0369035A1 (en) * | 1988-06-06 | 1990-05-23 | Mitsubishi Kasei Corporation | Agent for treating pancreatitis or the like |
US20030018013A1 (en) * | 2000-10-11 | 2003-01-23 | Dasseux Jean-Louis Henri | Ether compounds and compositions for cholesterol management and related uses |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
US20030105154A1 (en) * | 2001-10-24 | 2003-06-05 | Bisgaier Charles Larry | Statin-carboxyalkylether combinations |
US20020103252A1 (en) | 1997-12-12 | 2002-08-01 | Bisgaier Charles Larry | Statin-carboxyalkylether combinations |
US6861555B2 (en) | 2000-01-25 | 2005-03-01 | Warner-Lambert Company | Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith |
AU779784B2 (en) | 1999-04-01 | 2005-02-10 | Esperion Therapeutics Inc. | Ether compounds, compositions, and uses thereof |
US6645170B2 (en) | 2001-03-05 | 2003-11-11 | Bioject Medical Technologies, Inc. | Simplified disposable needle-free injection apparatus and method |
US20040229954A1 (en) * | 2003-05-16 | 2004-11-18 | Macdougall Diane Elaine | Selective manipulation of triglyceride, HDL and LDL parameters with 6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethylhexanoic acid monocalcium salt |
US7345190B2 (en) | 2003-11-12 | 2008-03-18 | Ssv Therapeutics, Inc. | Carnitine conjugates as dual prodrugs and uses thereof |
-
2011
- 2011-12-22 CN CN2011800630388A patent/CN103442707A/zh active Pending
- 2011-12-22 AU AU2011352449A patent/AU2011352449B2/en not_active Ceased
- 2011-12-22 MX MX2013007310A patent/MX337593B/es active IP Right Grant
- 2011-12-22 JP JP2013546406A patent/JP2014509305A/ja not_active Withdrawn
- 2011-12-22 EP EP16192597.9A patent/EP3170495B1/en active Active
- 2011-12-22 CN CN201710858297.9A patent/CN107648210A/zh active Pending
- 2011-12-22 CA CA2822921A patent/CA2822921C/en active Active
- 2011-12-22 DK DK11810759.8T patent/DK2658536T3/en active
- 2011-12-22 US US13/334,384 patent/US8846761B2/en active Active
- 2011-12-22 ES ES11810759.8T patent/ES2608177T3/es active Active
- 2011-12-22 WO PCT/US2011/066736 patent/WO2012092103A1/en active Application Filing
- 2011-12-22 HU HUE11810759A patent/HUE031004T2/en unknown
- 2011-12-22 EP EP11810759.8A patent/EP2658536B1/en active Active
- 2011-12-22 PT PT118107598T patent/PT2658536T/pt unknown
- 2011-12-22 PL PL11810759T patent/PL2658536T3/pl unknown
-
2015
- 2015-09-10 JP JP2015178843A patent/JP6207560B2/ja active Active
-
2017
- 2017-09-04 JP JP2017169145A patent/JP2018027953A/ja active Pending
-
2018
- 2018-08-01 HK HK18109899.3A patent/HK1250484A1/zh unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0369035A1 (en) * | 1988-06-06 | 1990-05-23 | Mitsubishi Kasei Corporation | Agent for treating pancreatitis or the like |
US20030018013A1 (en) * | 2000-10-11 | 2003-01-23 | Dasseux Jean-Louis Henri | Ether compounds and compositions for cholesterol management and related uses |
Non-Patent Citations (2)
Title |
---|
HAROLD E. BAYS等: "Effectiveness and tolerability of a new lipid-altering agent,gemcabene,in patients with low levels of high-density lipoprotein cholesterol", 《THE AMERICAN JOURNAL OF CARDIOLOGY》 * |
无: "Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report", 《CIRCULATION》 * |
Also Published As
Publication number | Publication date |
---|---|
CA2822921A1 (en) | 2012-07-05 |
AU2011352449A1 (en) | 2013-07-11 |
JP2018027953A (ja) | 2018-02-22 |
US8846761B2 (en) | 2014-09-30 |
JP2014509305A (ja) | 2014-04-17 |
JP6207560B2 (ja) | 2017-10-04 |
PL2658536T3 (pl) | 2017-04-28 |
MX2013007310A (es) | 2013-10-25 |
MX337593B (es) | 2016-03-11 |
EP2658536A1 (en) | 2013-11-06 |
CA2822921C (en) | 2018-07-17 |
EP3170495B1 (en) | 2023-04-26 |
PT2658536T (pt) | 2016-12-22 |
AU2011352449B2 (en) | 2015-06-18 |
EP2658536B1 (en) | 2016-10-19 |
JP2016028075A (ja) | 2016-02-25 |
HUE031004T2 (en) | 2017-06-28 |
ES2608177T3 (es) | 2017-04-06 |
US20120165411A1 (en) | 2012-06-28 |
EP3170495A1 (en) | 2017-05-24 |
DK2658536T3 (en) | 2017-01-09 |
WO2012092103A1 (en) | 2012-07-05 |
HK1250484A1 (zh) | 2018-12-21 |
CN107648210A (zh) | 2018-02-02 |
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C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20150127 Address after: michigan Applicant after: Yao Shi Treatment Co. Address before: Michigan Applicant before: Gemphire Therapeutics Inc. |
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