CN103432265B - A kind of Chinese medicinal composition preparation treating fever of children and preparation method thereof - Google Patents
A kind of Chinese medicinal composition preparation treating fever of children and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine composition treating fever of children and preparation method thereof.Traditional Chinese medicine composite composition is made up of Radix Platycodonis 10 15 parts, Herba Houttuyniae 25 35 parts, Folium Perillae 25 35 parts, 8 12 parts of Radix Glycyrrhizae.By Radix Platycodonis, Herba Houttuyniae, Folium Perillae, Radix Glycyrrhizae boiling twice, filter, obtain filtrate.Gained medicinal residues filter, and merging filtrate is concentrated into the 1/2 of filtrate volume, obtains concentrated solution.Above-mentioned concentrated solution is concentrated into 80 DEG C of thick extractum recording relative density 1.21 1.25.Shift-in baking oven, dries to moisture less than 5%, takes out, make capsule, tablet, decoction, granule or oral solutions by state of the art for 50 70 DEG C.
Description
Technical field
The present invention relates to a kind of Chinese medicinal composition preparation treating fever of children and preparation method thereof, belong to Chinese medicine neck
Territory.
Background technology
Heating is one of modal symptom of infantile common cold disease, is the defensive reaction of health that various disease causes, and sends out
Heat refers to that pathologic body temperature raises, or conscious heating is main symptom.Heating is that human body is anti-to a kind of whole body of virulence factor
Should, for clinical pole common sympton, it is, in general, that heat production and heat radiation are under the regulation of heat center, make body temperature maintain on 37 DEG C
Under, every day, body temperature difference was less than 1 DEG C.The heat production ＞ heat radiation that any reason causes, then will cause body temperature to raise, referred to as heating,
The cause of disease of fever of children is a lot, can be divided into infectious and non-infectious clinically, common with infectivity, infects and includes antibacterial sense
Dye and virus infect and fungal infection etc., if flu etc. is the modal cause of disease, need first, it is settled that the cause of disease, pin for heating
The cause of disease is processed, when body temperature raises (38 DEG C～39 DEG C) its health be responsible for swallow antibacterial leukocyte phagocytic activity add
By force, heating will attract great attention more than 38 degree, easily cause children with high fever induced convulsions during hyperpyrexia, so must control volume
Temperature, the method mainly using drug cooling and Physical temperature-lowering, Chinese medicine fever of children has certain advantage, the most not
There is the toxic and side effects of Western medicine, the most also occur in that the Chinese medicine preparation of some treatment fever of children, but these treat children's
The Chinese medicine preparation of heating has certain curative effect to children's, but effective percentage is the best, and pharmaceutical preparation is many.
Summary of the invention
For the problem of above-mentioned existence, the present invention provides a kind of Chinese medicinal composition preparation treating fever of children and preparation thereof
Method
The technical solution adopted in the present invention is:
A kind of Chinese medicinal composition preparation treating fever of children, including the raw material of following weight portion:
Radix Platycodonis 10-15 part, Herba Houttuyniae 25-35 part, Folium Perillae 25-35 part, Radix Glycyrrhizae 8-12 part.
Further preferred as technique scheme, described Chinese medicinal composition preparation includes the former material of following weight portion
Material:
Radix Platycodonis 12 parts, Herba Houttuyniae 30 parts, Folium Perillae 30 parts, 10 parts of Radix Glycyrrhizae.
The present invention treats the Chinese medicinal composition preparation of fever of children, and dosage form is capsule, tablet, decoction, granule or mouth
Take liquor.
The preparation method of a kind of Chinese medicinal composition preparation treating fever of children, comprises the following steps:
A, proportionally take the mixing of each composition of raw material, boiling 30 minutes water decoction.
B, by Radix Platycodonis, Herba Houttuyniae, Folium Perillae, Radix Glycyrrhizae boiling twice, filter, filtrate is concentrated into the 1/2 of filtrate volume,
Concentrated solution.
Gained medicinal residues filter, and merging filtrate is concentrated into the 1/2 of filtrate volume, obtains concentrated solution.
C, above-mentioned concentrated solution are concentrated into 80 DEG C of thick extractum recording relative density 1.21～1.25.Shift-in baking oven, 50-70 DEG C
Dry to moisture less than 5%, take out
Capsule, tablet, decoction, granule or oral solutions is controlled into by state of the art.
In above raw material,
Radix Platycodonis bitter in the mouth, pungent, property is put down.Return lung meridian.Effect lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.Radix Platycodonis is still regulated the flow of vital energy, invigorates blood circulation, is disappeared
Food, sedative action.Now research Radix Platycodonis has calmness, analgesia, refrigeration function, has antibacterial action, to multiple coccus, bacillus and cotton-shaped
Epidermophyton has inhibitory action, has antiinflammatory and immunological enhancement.
Herba Houttuyniae acrid in the mouth, cold nature, there is heat-clearing and toxic substances removing；Removing pus and relieving carbuncle；Effect of inducing diuresis for treating stranguria syndrome, treats lung abscess vomiting pus；
Expectorant dyspnea of heat type is coughed；Larynx；Hematodiarrhoea；For treating lung-heat, expectorant heat, lung abscess, cough the key medicine of vomiting bloody pus.Can be additionally used in pathopyretic ulcer, wet
Pyretic stranguria is demonstrate,proved, damp-heat dysentery.
Folium Perillae effect relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach.For anemofrigid cold, vomiting and nausea of coughing, vomiting during pregnancy, fish Eriocheir sinensis is poisoned.Purple
Folium Perillae can dissipate exterior cold, and diaphoresis power is relatively strong, for wind and cold table disease, sees aversion to cold, heating, the disease such as lossless
Radix Glycyrrhizae effect invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, tired
Idle weak, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
The traditional Chinese medical science thinks that fever of children is mainly yang-energy stasis in vivo, it is impossible to normal a surname has carried out the coffin upon burial.Because children's Yang Chang has
Remaining, the physiological characteristics of YIN often being in shortage, a lot of acute and chronic diseases card all has the symptom of heating.Therefore ZHU Dan-xi: all children's are ill the hottest.King
Willing party: the disease of children's, the hottest in the majority.Heating is simply divided into exterior heat interior-heat deficiency-heat excess-heat fever of children to demonstrate,prove by " A complete work on Pediatrics, a collection and arrangement of the chief contents from ancient pediatrics, written by Chen Fuzheng " can
It is divided into two big classes: fever caused by exogenous pathogens and interior syndrome generate heat.
Present invention application Folium Perillae relieving exterior syndrome and dispelling cold, reaches yang-energy thoroughly. Herba Houttuyniae heat-clearing and toxic substances removing, lung heat clearing defend Radix Platycodonis lung qi dispersing eliminate the phlegm,
To regulate the flow of vital energy and calm the nerves. Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing four medicine coordinates plays heat clearing away of inducing sweat altogether, the merit that lung qi dispersing is regulated the flow of vital energy
The present invention compared with prior art, has the advantage that monarch of the present invention, minister, helps, makes respectively to execute its effect, have medication
Few, instant effect, side effect is little, rapid recovery clinical symptoms, and therapeutic effect is good.Raw material of the present invention is bought convenient, low price,
Easy to make, it is worthy of popularization.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1,
A kind of treat fever of children Chinese medicinal composition preparation, described medicine is made up of the raw material of following weight portion:
Radix Platycodonis 10 parts, Herba Houttuyniae 25 parts, Folium Perillae 25 parts, 8 parts of Radix Glycyrrhizae.
The present invention treats the Chinese medicinal composition preparation of fever of children, and dosage form is capsule, decoction, tablet, granule or mouth
Take liquor.
Preparation method, comprises the following steps:
A, proportionally take the mixing of each composition of raw material, boiling 30 minutes water decoction.
B, by Radix Platycodonis, Herba Houttuyniae, Folium Perillae, Radix Glycyrrhizae boiling twice, filter, filtrate is concentrated into the 1/2 of filtrate volume,
Concentrated solution.
Gained medicinal residues filter, and merging filtrate is concentrated into the 1/2 of filtrate volume, obtains concentrated solution.
C, above-mentioned concentrated solution are concentrated into 80 DEG C of thick extractum recording relative density 1.21～1.25.Shift-in baking oven, 50-70 DEG C
Dry to moisture less than 5%, take out
Capsule, tablet, granule or oral solutions is controlled into by state of the art.
Embodiment 2,
A kind of treat fever of children Chinese medicinal composition preparation, described medicine is made up of the raw material of following weight portion:
Radix Platycodonis 12 parts, Herba Houttuyniae 30 parts, Folium Perillae 30 parts, 10 parts of Radix Glycyrrhizae.
Preparation method is same as in Example 1
Embodiment 3,
A kind of treat fever of children Chinese medicinal composition preparation, described medicine is made up of the raw material of following weight portion:
Radix Platycodonis 15 parts, Herba Houttuyniae 35 parts, Folium Perillae 35 parts, 12 parts of Radix Glycyrrhizae.
Preparation method is same as in Example 1.
Contrast test:
Criterion of therapeutical effect is drafted with reference to<<traditional Chinese medical science Pediatrics Department Illnesses Diagnoses criterion of therapeutical effect>>: axil temperature 37.5～38 DEG C are low grade fever,
38.1～39 DEG C are generated heat for moderate, and 39.1～40.5 DEG C is high heat, and ＞ 40.5 DEG C is excessive heat, includes treatment in 38.1～39 DEG C
Scope. effective: the oral drugs body temperature that generates heat after two hours is normal, less than 37.5 DEG C effectively: oral drugs generated heat after two hours
Turn remain above 37.5 DEG C invalid: oral drugs generate heat unchanged after two hours or increase
Choose 400 example fever of children patients (including acute/chronic bronchitis cough, upper respiratory tract infection, pneumonia, disease
Toxicity cold patients), randomly select 300 examples as treatment group, as a control group, wherein 300 example patients are divided into and controlling other 100 examples
Treatment group 1, treatment group 2 and treatment group 3, the 100 example patients that the treatment of each treatment group randomly selects, treatment group 1 uses the present invention real
The water decoction executing example 1 preparation is treated, and the water decoction that treatment group 2 uses the embodiment of the present invention 2 to prepare is treated, treatment group
3 use the water decoction of the embodiment of the present invention 3 preparation to treat.
The patient of matched group uses conventional application ibuprofen suspension to be administered orally, and is simultaneous for the cause of disease and treats.Treatment group
Add medicine water decoction of the present invention, be simultaneous for the cause of disease and treat.
Therapeutic outcome such as following table:
From data above table it can be seen that treatment group effective percentage obvious effective rate is apparently higher than matched group, the cure rate for the treatment of group 2
Effective percentage is higher than remaining treatment group, and treatment group in sum 2 prescription is maximally efficient.
Claims (3)
1. treat a Chinese medicine composition for fever of children, it is characterized in that: described Chinese medicine composition is by the former material of following weight portion
Material is made:
Radix Platycodonis 10-15 part, Herba Houttuyniae 25-35 part, Folium Perillae 25-35 part, Radix Glycyrrhizae 8-12 part.
2. the Chinese medicine composition treating fever of children as claimed in claim 1, is characterized in that: described Chinese medicine composition is by following
The raw material of weight portion is made:
Radix Platycodonis 12 parts, Herba Houttuyniae 30 parts, Folium Perillae 30 parts, 10 parts of Radix Glycyrrhizae.
3. the Chinese medicine composition treating fever of children as claimed in claim 1 or 2, is characterized in that: described Chinese medicine composition agent
Type is: capsule, tablet, decoction, granule or oral solutions.
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| CN105168582A (en) * | 2015-10-12 | 2015-12-23 | 长沙秋点兵信息科技有限公司 | Traditional Chinese medicine composite for treating child cold and preparation method thereof |
| CN105535927A (en) * | 2016-01-29 | 2016-05-04 | 山东中海制药有限公司 | Medicine used for treating influenza, upper respiratory infection and viral pneumonia |
| CN109602875B (en) * | 2019-01-28 | 2021-05-11 | 帅云飞 | Traditional Chinese medicine composition for treating infantile fever as well as preparation method and application thereof |
| CN111328899A (en) * | 2020-02-25 | 2020-06-26 | 深圳神思汉方生物科技有限公司 | Orange, cattail and perilla herb substituted tea and preparation method thereof |
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| CN101147788A (en) * | 2007-04-11 | 2008-03-26 | 秦庆吉 | Medicine for treating cold and upper respiratory tract infection and its lung inflammation |
| CN101439175A (en) * | 2008-12-25 | 2009-05-27 | 杭州万得富生物技术有限公司 | Chinese medicine preparation for treating nephropathogenic infectious bronchitis in chicken |
| CN102743666A (en) * | 2012-06-07 | 2012-10-24 | 无为县陡沟镇中心卫生院 | Electuary for treating exogenous fever |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101147788A (en) * | 2007-04-11 | 2008-03-26 | 秦庆吉 | Medicine for treating cold and upper respiratory tract infection and its lung inflammation |
| CN101439175A (en) * | 2008-12-25 | 2009-05-27 | 杭州万得富生物技术有限公司 | Chinese medicine preparation for treating nephropathogenic infectious bronchitis in chicken |
| CN102743666A (en) * | 2012-06-07 | 2012-10-24 | 无为县陡沟镇中心卫生院 | Electuary for treating exogenous fever |
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Inventor after: Liu Chunyan Inventor after: Chu Lingzhi Inventor after: Luan Honghuan Inventor before: Sun Fengqing |
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Effective date of registration: 20160623 Address after: Derek street in Jimo City, Shandong province 266200 Qingdao City No. 4 people's Hospital of Jimo City Applicant after: Liu Chunyan Address before: The third people's Hospital of Shandong Province, No. 3 Haiyang city 265100 Shandong city of Yantai province Haiyang City, Hai Hua Lu Applicant before: Sun Fengqing |
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