CN103431393A - Coarse grain full-nutrition formula food for patients with respiratory diseases - Google Patents

Coarse grain full-nutrition formula food for patients with respiratory diseases Download PDF

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CN103431393A
CN103431393A CN201310385618XA CN201310385618A CN103431393A CN 103431393 A CN103431393 A CN 103431393A CN 201310385618X A CN201310385618X A CN 201310385618XA CN 201310385618 A CN201310385618 A CN 201310385618A CN 103431393 A CN103431393 A CN 103431393A
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chinese
patients
vitamin
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CN103431393B (en
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王宗继
焦念强
杜广青
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RIZHAO ZHONGSHENG MARINE BIOTECHNOLOGY Co.,Ltd.
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SHANDONG WEIKANG BIOMEDICAL SCIENCE AND TECHNOLOGY CO LTD
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Abstract

The invention discloses coarse grain full-nutrition formula food for patients with respiratory diseases, which relates to the technical field of healthcare food. The coarse grain full-nutrition formula food is prepared from peanut, black bean, black rice, a Chinese medicine extracting solution, vitamin C, taurine, selenium-enriched yeast, stevioside and edible essence, wherein the Chinese medicine extracting solution is a concentrated solution of an aqueous extract of fritillary, platycodon root, ephedra, motherwort, codonopsis pilosula, licorice, cassia twig, asarum, ginger and fructus schizandrae. On the basis of providing rich nutrient substances, the food disclosed by the invention further reinforces vitamin C, taurine and trace element selenium; as Chinese medicine composition ingredients are added in the food, the food has a good curative effect on such respiratory diseases as flu, bronchitis, wheeze, pneumonia, emphysema, bronchiectasis and allergic rhinitis; the food can be used as auxiliary treatment nutrient food for patients with respiratory diseases and healthcare food for preventing respiratory diseases.

Description

A kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients
Technical field
The present invention relates to the health food technology field, be specifically related to a kind of full nutrient formulation food for the respiratory disease edible for patients.
Background technology
Respiratory disease is a kind of common disease, frequently-occurring disease, and major lesions is in tracheae, bronchus, lung and thoracic cavity, and the many coughs of pathology the lighter, pectoralgia, breathing are influenced, severe one expiratory dyspnea, anoxic, even respiratory failure and lethal.The death rate in city accounts for the 3rd, accounts for first place in rural area.What more should pay attention to is due to atmosphere pollution, smoking, aging population and other factors, make chronic obstructive pulmonary disease both domestic and external (be called for short chronic obstructive pulmonary disease, comprise chronic bronchitis, pulmonary emphysema, pulmonary heart disease), bronchial astehma, lung cancer, lung's dispersivity interstitial fibrosis, and the incidence of disease, the death rate of the disease such as pulmonary infection are growing on and on.
Since the end of the year 2002, severe acute respiratory syndrome (the serious acute respiratory syndrome broken out in China and world wide, SARS) epidemic situation, due to the multiple the young and the middle aged of being born in, its infectiousness is strong, and case fatality rate is high, lacks again medicine targetedly, thereby caused the masses' fear, to national economy, bring about great losses simultaneously.The human avian influenza case fatality rate occurred in a plurality of countries at present surpasses 60%.And avian influenza virus to invade main target organ in human body be also lung.It is very large that this is just illustrating that respiratory disease is still Chinese people's health hazard, and it prevents and treats arduous task.
The controlling way of respiratory disease:
1, reconditioner body immunity function
The morbidity of respiratory system is relevant with immune dysfunction due to the disorder of immunocyte electrical activity and quantum balancing imbalance.Has immune response also occurred in the optimal stimulation thing that why human body is had no to injure? this is mainly due to immune function of human body is lacked of proper care.Immune surveillance system has recognition of nonself, eliminates the dissident, the pure stabilization of environment in keeping.When immune surveillance function is lacked of proper care, lost the recognition of nonself ability, fail to differentiate between the enemy and ourselves, the fresh flower poisonous weeds regardless of, the original material harmless to health, think that harmful enemy is that antigen is removed by mistake.Therefore, the tracheitis pathogenesis is due to immune dysfunction.Negative oxygen ion has the immunocyte quantum balancing of adjustment and albumen dish knot function, thereby reaches function normalization.Adjust immunity function, can make the immunologic function normalization of imbalance, eliminate the body allergy, reach the effect for the treatment of respiratory disease. ? 
2, regulating plant nerve dysfunction
This is two of respiratory system pathogenesis: vagal excitation is too high, and sympathetic activation, liken them to rebel faction and two kinds of force of royalist suit somebody to a T.Any drug therapy tracheitis reaches result for the treatment of by changing these two kinds of force mostly. ? 
3, improve acidic constitution
The functional activity of each cell of human body all must carry out in a suitable acid-base balance environment, and normal person's acid-base value is that PH=7.41 is alkalescent, and the elderly is because the acid discharge miopragia easily becomes acidic constitution.In tense working pressure and stress or eat a little too much acidic foods and can cause interior environment disturbance, dysbolism can be facilitated acidic constitution for a long time.Mast cell in sour environment, its stability of destructible and de-particle reaction occurs.Therefore, the respiratory system patient should eat meat less, eats vegetable and fruit more, strengthens oneself's adjustment and alleviates psychological pressure.Respiratory disease patient is long-term inhale take in ion and body in H+(H+ with positive charge, and ion with negative electrical charge can with in and too much H+ in body), this is the key factor that determines the body inner acidic; Can protect the alkali function by the acid discharge that strengthens respiratory system, hematological system, urinary system simultaneously and improve acidic constitution, be of value to the treatment of tracheitis. ? 
4, control respiratory tract infection
Vagus nerve is distributed on bronchus and alveolar, because but the bronchitis vagus nerve stimulation makes its excitement, this is to cause one of respiratory disease reason, and ion can directly be eliminated bronchitis, minimizing, to vagal stimulation, maintains balance between sympathetic nerve and vagus nerve.In sum, the tracheitis pathogenesis is too many levels, and therefore, the medicine of single preparations of ephedrine, be difficult to prove effective.Negative oxygen ion has the characteristics of " many diseases are ruled together ", and treatment tracheitis has unique advantage.West Germany scholar Suhl is grown with the routine tracheitis patient of ion treatment 3000, efficiently reaches 97.4%.
From pathogenesis, respiratory disease morbidity is wide, infectivity, easily outbreak repeatedly, easily form chronic disease, in view of these characteristics, for respiratory disease, prevention overweights treatment, at regular life at ordinary times, reinforcement physical exercise, and the health food of assisting some can strengthen immunity all can be received good effect.
Mostly the treatment of respiratory disease is to treat to the ill by the chemicals anti-inflammation and sterilization, although but often at when treatment instant effect, but should not dig up the roots, cough that can be for a long time, pant, inflammation etc., if thereby but be aided with treatment by Chinese herbs can receive the effect that reinvigoration, beneficial gas bowl spares are dug up the roots.
The present invention just is being based on this point, meticulously forms a Chinese prescription on the basis of traditional proved recipe and clinical experience, and the party has no side effect, and respiratory disease is had to the effect of broad spectrum activity.This prescription and the food nutrition formula that improves body immunity are combined, make a kind of health food that prevention and auxiliary curing respiratory disease is all had to the effect of applauding.
Summary of the invention
The objective of the invention is to manufacture a kind of for respiratory disease patient and the edible health food of colony that potential trouble respiratory disease risk is arranged, this food can strengthen immunity prevention respiratory disease, also can play to respiratory disease the effect of auxiliary curing.
In order to reach above purpose; it is primary raw material that peanut, black soya bean, black rice are take in the present invention; add vitamin C, taurine, Se-enriched yeast forced for vitamins and trace element and can strengthen immunity, add again Chinese medicine extract and increase the therapeutic action to respiratory disease.This food, on the basis that the abundant nutrition material is provided, has further been strengthened vitamin C, taurine and trace elements of selenium, and adds the Chinese prescription composition, respirability systemic disease patient or have potential trouble respiratory disease risk person edible.
A kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients disclosed in this invention, the proportioning of its each raw material is counted with weight portion: shelled peanut 25-35 part, black soya bean 10-15 part, black rice 8-12 part, Chinese medicine extract 8-11 part, vitamin C 0.4-0.8 part, taurine 0.2-0.4 part, Se-enriched yeast 0.001-0.0013 part, steviol glycoside 0.1-0.3 part, flavoring essence 0.01-0.014 part; Wherein optimum proportioning is counted with weight portion: 30 parts, shelled peanut, 12 parts, black soya bean, 11 parts of black rices, 10 parts of Chinese medicine extracts, 0.6 part of vitamin C, 0.3 part of taurine, 0.0012 part of Se-enriched yeast, 0.2 part of steviol glycoside, 0.012 part of flavoring essence.The prescription of the Chinese medicine extract in formula is counted with weight portion: tendril-leaved fritillary bulb 11-18 part, balloonflower root 12-16 part, Chinese ephedra 8-12 part, motherwort 7-11 part, Radix Codonopsis 11-14 part, Radix Glycyrrhizae 8-12 part, cassia twig 8-12 part, root of Chinese wild ginger 7-10 part, rhizoma zingiberis 7-12 part, fruit of Chinese magnoliavine 9-11 part; Optimum Chinese prescription is counted with weight portion: 15 parts of tendril-leaved fritillary bulb, 13 parts of balloonflower roots, 10 parts, Chinese ephedra, 9 parts of motherworts, 12 parts of Radix Codonopsis, 10 parts, Radix Glycyrrhizae, 10 parts of cassia twig, 8 parts of the roots of Chinese wild ginger, 10 parts of rhizoma zingiberis, 10 parts, the fruit of Chinese magnoliavine.
The preparation method of food of the present invention is:
1) respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2) by previously described Chinese prescription, accurately take respectively: tendril-leaved fritillary bulb, balloonflower root, Chinese ephedra, motherwort, Radix Codonopsis, Radix Glycyrrhizae, cassia twig, the root of Chinese wild ginger, rhizoma zingiberis, the fruit of Chinese magnoliavine.Pulverize respectively, mix, add the purified water of 8 times of weight, reflux and decoct 1 hour, a filters to get filtrate; The purified water that adds 6 times of weight in filter residue, then the decoction 1 hour that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be Chinese medicine extract, standby;
3) take respectively shelled peanut, black soya bean, black rice, Chinese medicine extract, vitamin C, taurine, Se-enriched yeast, steviol glycoside, flavoring essence by described formula above, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
4) by 3) gained pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 30-70g, be finished product.
Nutraceutical of the present invention, can make powdery or graininess, with warm water, dissolves and to take, and also can make block food (can not baking), directly eats.
A kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients provided by the present invention, its primary raw material is:
Peanut: the protein content of peanut is 25%-30%, eight seed amino acids that peanut protein contains needed by human, and arginine content is higher than other nut, and biological value is higher than soybean.Eat a certain amount of peanut, peanut oil or (Groundnut products) every day, a large amount of albumen, fat and energy can not only be provided and can reduce the meals saturated fat and the absorption of increase unrighted acid, greatly promote these absorptions to healthy and helpful nutrient such as phytoprotein, dietary fiber, vitamin E, folic acid, potassium, magnesium, zinc, calcium.
From traditional Chinese medical science angle, peanut is good simply Chinese medicine, according to Liang Yao state traditional Chinese physician, means: " peanut has the function of happy spleen and stomach, moistening lung for removing phlegm, nourishing regulating the qi flowing in the channels, for symptom malnutritive and the cough asthma due to excessive phlegm, have curative effect.”
Peanut nutrition enriches and has the effect of moistening lung for removing phlegm, and therefore, the present invention be take it as primary raw material.
Black soya bean: black soya bean, have another name called big shield beans, material beans, zero black beans, teata glycinis and the equine beans of claiming among the people, to the laudatory title that the king in beans is arranged more.The black soya bean anti-senility, the medicine food is all good.Black soya bean is containing rich in protein, unrighted acid, phosphide, calcium, phosphorus, iron, potassium, sodium, carrotene, vitamin B1, vitamin B2, cobalamin, nicotinic acid, folic acid, choline, daizeol, saponin(e etc.Black soya bean is put down, distinguishes the flavor of sweet; Return spleen, kidney channel; Have that the lower gas of detumescence, moistening lung are scorching, the Zhichuan of eliminating the phlegm, activating blood and promoting diuresis, wind expelling stagnation removing, blood-enriching tranquillizing, improving eyesight invigorating the spleen, kidney tonifying benefit are cloudy, the effect of removing toxic substances; For oedema turgor, pathogenic wind-toxic beriberi, jaundice edema, wandering arthritis spasm, cold after delivery pain, mouthful keep silent, carbuncle sore tumefacting virus, but the antidote poison, wind-heat processed and night sweat only, crow blackout and the function of promoting longevity.
Not only nutrition and trace element is abundant, more can moistening lung scorching, the Zhichuan of eliminating the phlegm, treatment cough of black soya bean, therefore be chosen as raw material of the present invention.
Black rice: black rice is the rice of a kind of medicine, food dual-purpose, belongs to the glutinous rice class.Black rice is containing nutrients such as protein, carbohydrate, B family vitamin, vitamin E, calcium, phosphorus, potassium, magnesium, iron, zinc, nutritious; Black rice has the free radical of removing, improves the different physiological roles such as hypoferric anemia, anti allergic reaction and immunological regulation; Brass compounds in black rice can maintain the normal osmotic pressure of blood vessel, alleviates fragility of blood vessels, prevents angiorrhoxis and hemostasis; Black rice has antibiotic, the effect of reduce blood pressure, inhibition cancer cell being grown; Black rice also has the myocardial nutrition of improvement, reduces the effects such as MCO.
Black rice does not singly contain abundant nutrition and trace element, and can also improve myocardial nutrition, strengthen immunity is the good merchantable brand improved the health, therefore used for the present invention.
Chinese medicine extract: the present invention's Chinese medicine extract used is by the accurate weighing ingredients of Chinese prescription above, pulverizes the purified water that adds 8 times, refluxes and decocts 1 hour, and a filters to get filtrate; Filter residue is added again to the water of 6 times, continuing to reflux decocts 1 hour, and the b that filters to get filtrate, mix a and b, and 1/2 of simmer down to original volume, be Chinese medicine extract.Wherein ingredients is respectively:
Tendril-leaved fritillary bulb: cool in nature, sweet flat.Enter lung channel, stomach warp.The resolving sputum and relieving asthma that moistens the lung and relieve the cough, clearing heat and eliminating phlegm.
Balloonflower root: bitter; Hot; Property is put down.Enter lung channel.A surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, sharp the five internal organs, fill blood, mend the exhaustion or lesion of the five internal organs, foster the spirit of nobility.Cure mainly coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache, aphthae, red eye, swell pain, uroschesis.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, hoarsen, the lung carbuncle pyemesis, sore purulence does not become to burst.
Chinese ephedra: property is hot, micro-hardship, temperature.Return lung, urinary bladder channel.Pulvis Diaphoreticus is cold, freeings lung and relieving asthma, and inducing diuresis for removing edema.For anemofrigid cold, uncomfortable in chest breathing with cough, geomantic omen edema; Bronchial astehma.
Motherwort: mildly bitter flavor, micro-suffering.Be slightly cold, property is sliding.Enter the heart, liver, urinary bladder channel.Invigorate blood circulation, the stasis of blood of dispelling, menstruation regulating, water disappears.Control irregular menstruation, threatened abortion difficult labour, placenta retension, postpartum anemic fainting, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rush down blood, the carbuncle sore that swells.
Radix Codonopsis: property is sweet, flat.Return spleen, lung channel.There is tonifying middle-Jiao and Qi, the effect of invigorating the spleen benefit lung.For a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst.
Radix Glycyrrhizae: distinguish the flavor of sweet, property is flat, nontoxic.Cure mainly vital organs of the human body fever and chills perverse trend, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Give birth to and use purging intense heat heat, the ripe use exterior cold of fall apart, go pharyngalgia, remove heat symptoms caused by an exopathgen, delay healthy tendency, yin-nourishing blood, tonifying spleen and stomach, moistening lung.
Cassia twig: acrid, sweet, warm.The thoughts of returning home, lung, urinary bladder channel.The sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, help yang transforming qi, making the adverse-rising QI downwards.
The root of Chinese wild ginger: property suffering, temperature.The thoughts of returning home, lung, kidney channel.Expelling wind and clearing away cold, understand things pain-stopping, warming lung to reduce watery phlegm.For anemofrigid cold, headache, toothache, the nasal obstruction nasosinusitis, arthralgia due to wind-dampness, phlegm and retained fluid is breathed with cough.
Rhizoma zingiberis: property is hot, hot.Return spleen, stomach, kidney, the heart, lung channel.The rhizoma zingiberis warming spleen and stomach for dispelling cold, Hui Yang promotes blood circulation, the eliminating dampness dissolving phlegm.For coldness and pain in the epigastrium, vomiting is had loose bowels, the cold weak pulse of limb, and phlegm and retained fluid is breathed with cough.
The fruit of Chinese magnoliavine: property acid, sweet, temperature.Return lung, the heart, kidney channel.There is convergence astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, the effect of kidney calming.For the void of coughing for a long time, breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the feeble pulse of losing heart, interior heat is quenched one's thirst, palpitation and insomnia.
Chinese medicine extract prescription used in the present invention is allotment and determining meticulously on the basis of summing up clinical experience and traditional proved recipe, and has passed through long clinical examination.From the clinical testing the party to influenza, bronchitis, pant, the respiratory disease such as pneumonia, pulmonary emphysema, bronchiectasis and allergic rhinitis has result for the treatment of preferably.
Vitamin C: being again L-AA, is a kind of water soluble vitamin.Vitamin C has very high using value aspect antiviral and preventing viral infectious disease.Because vitamin C can improve the immunity of human body: leucocyte contains abundant vitamin C, and when organism infection, intraleukocytic vitamin C sharply reduces.Vitamin C can strengthen chemotaxis and the deformability of neutrophil leucocyte, improves sterilizing ability.Promote lymphoblastic generation, improve body to the identification of external and malignant cell and kill.Participate in the synthetic of immunoglobulin (Ig).Improve CI complement esterase active, increase the generation of complement CI.Promote the generation of interferon, viral interference mRNA transcribes, and suppresses viral hyperplasia.Vitamin C can also improve the emergency capability of body in addition: human body is subject to abnormal stimulation, as severe pain, cold, anoxic, spiritual strong stimulation, can cause the tense situation of resisting abnormal stimulation.This state, with a series of healths, comprises sympathetic activation, adrenal medella and cortin secretion increasing.The adrenaline that adrenal medella is secreted and norepinephrine are to have tyrosine to be transformed, in the participation of this process need VC.
Forced for vitamins C of the present invention can allow the eater strengthen immunity and anti-virus ability, thereby can prevent and treat respiratory disease.
Taurine: taurine claims again Tau.Be a kind of non-protein amino acid of sulfur-bearing, exist with free state in vivo, do not participate in the biosynthesis of albumen in body.Taurine can promote pituitrin secretion, the activation pancreas function, thereby improve the state of organism endocrine system, to organism metabolism with useful adjusting; And there is the enhancing that promotes organism immunity and the effect of antifatigue.
It is in order to allow the eater further strengthen immunity and anti-fatigue ability that the present invention strengthens taurine, thereby respiratory disease is had to good resistance.
Se-enriched yeast: Se-enriched yeast is exactly to add the selenium element in the process of culture yeasts, absorbed selenium during yeast growth, the protein of selenium in the yeast body and polysaccharide organic are combined and are converted into Biological Selenium, thereby eliminated chemical selenium (as sodium selenite), the toxicity of human body and stomach are stimulated, make the selenium utilization that can more efficiently, more safely be absorbed by the body.Se-enriched yeast be also up to now domestic the most efficiently, the selenium-replenishing preparation that the safest, nutrition is the most balanced.
The edible Se-enriched yeast of the present invention is the finished product Se-enriched yeast powder above containing selenium 2000mg/kg, and adding Se-enriched yeast is for reinforced micro-element selenium, because the selenium element is the vectorial mineral nutrient of needed by human, in human body, can't synthesize.And selenium can strengthen body immunity, scarce selenium can cause the immunocompetence of human body to descend.
Strengthening selenium can allow the eater further strengthen immunity.
Compared with prior art, a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients disclosed by the invention has following characteristics and significantly technological progress:
1, food nutrition provided by the present invention is abundant, contains a large amount of protein, multiple unrighted acid, trace element, vitamin etc., and these abundant nutritional labelings are that trouble patient and person in poor health are badly in need of.Abundant nutrition foundation can strengthen the ability of resisting respiratory disease.
2, food provided by the present invention has also been strengthened vitamin C, taurine, selenium; through a series of formula, grope; find a proportioning that these three kinds of materials and abundant base nutrients matter can be complemented each other; thereby can more effectively strengthen immunity of organisms, anti-virus ability; strengthen physique, allow the eater there is good resistance to respiratory disease.
3, food provided by the present invention has also added Chinese medicine extract, by formula repeatedly, grope, find a proportioning that traditional Chinese medicine ingredients, trace element and abundant nutrient are acted synergistically, present significant curative effect in the process of auxiliary curing respiratory disease, the analysis result of concrete visible embodiment 6.
4, the without any side effects and harm of food provided by the present invention, singly not can be used as the aid nutrition product in when treatment, can also be as the health products of the colony that trouble respiratory disease potential risk is arranged.
the specific embodiment:
Form is described in further detail foregoing of the present invention again by the following examples, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following embodiment, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
The preparation of embodiment 1 compound prescription nutrient powder:
1, respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2, by Chinese prescription above, accurately take respectively: tendril-leaved fritillary bulb 1100g, balloonflower root 1200g, Chinese ephedra 800g, motherwort 700g, Radix Codonopsis 1100g, Radix Glycyrrhizae 800g, cassia twig 800g, root of Chinese wild ginger 700g, rhizoma zingiberis 700g, fruit of Chinese magnoliavine 900g.Pulverize respectively, mix, add the purified water of 8 times of weight, reflux and decoct 1 hour, a filters to get filtrate; The purified water that adds 6 times of weight in filter residue, then the decoction 1 hour that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be Chinese medicine extract, standby;
3, take respectively shelled peanut 25kg, black soya bean 10kg, black rice 8kg, Chinese medicine extract 8kg, vitamin C 0.4kg, taurine 0.2kg, Se-enriched yeast 0.001kg, steviol glycoside 0.1kg, flavoring essence 0.01kg, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
4, will mix pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 30-70g, be finished product.
The preparation of embodiment 2 compound prescription nutrient powder:
1, respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2, by Chinese prescription above, accurately take respectively: tendril-leaved fritillary bulb 1800g, balloonflower root 1600g, Chinese ephedra 1200g, motherwort 1100g, Radix Codonopsis 1400g, Radix Glycyrrhizae 1200g, cassia twig 1200g, root of Chinese wild ginger 1000g, rhizoma zingiberis 1200g, fruit of Chinese magnoliavine 1100g.Pulverize respectively, mix, add the purified water of 8 times of weight, reflux and decoct 1 hour, a filters to get filtrate; The purified water that adds 6 times of weight in filter residue, then the decoction 1 hour that refluxes, b filters to get filtrate; Filtrate a and b are mixed, make cumulative volume be reduced to 1/2 of original volume, be Chinese medicine extract, standby;
3, take respectively shelled peanut 35kg, black soya bean 15kg, black rice 12kg, Chinese medicine extract 11kg, vitamin C 0.8kg, taurine 0.4kg, Se-enriched yeast 0.0013kg, steviol glycoside 0.3kg, flavoring essence 0.014kg, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
4, will mix pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 30-70g, be finished product.
The preparation of embodiment 3 compound prescription nutrient powder:
1, respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2, by Chinese prescription above, accurately take respectively: tendril-leaved fritillary bulb 1300g, balloonflower root 1500g, Chinese ephedra 900g, motherwort 800g, Radix Codonopsis 1300g, Radix Glycyrrhizae 1100g, cassia twig 900g, root of Chinese wild ginger 900g, rhizoma zingiberis 900g, fruit of Chinese magnoliavine 1000g.Pulverize respectively, mix, add the purified water of 8 times of weight, reflux and decoct 1 hour, a filters to get filtrate; The purified water that adds 6 times of weight in filter residue, then the decoction 1 hour that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be Chinese medicine extract, standby;
3, take respectively shelled peanut 33kg, black soya bean 12kg, black rice 9kg, Chinese medicine extract 9kg, vitamin C 0.5kg, taurine 0.2kg, Se-enriched yeast 0.0011kg, steviol glycoside 0.2kg, flavoring essence 0.012kg, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
4, will mix pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 30-70g, be finished product.
The preparation of embodiment 4 compound prescription nutrient powder:
1, respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2, by Chinese prescription above, accurately take respectively: tendril-leaved fritillary bulb 1500g, balloonflower root 1300g, Chinese ephedra 1000g, motherwort 900g, Radix Codonopsis 1200g, Radix Glycyrrhizae 1000g, cassia twig 1000g, root of Chinese wild ginger 800g, rhizoma zingiberis 1000g, fruit of Chinese magnoliavine 1000g.Pulverize respectively, mix, add the purified water of 8 times of weight, reflux and decoct 1 hour, a filters to get filtrate; Add again the purified water of 6 times of weight in filter residue, then the decoction 1 hour that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be Chinese medicine extract, standby;
3, take respectively shelled peanut 30kg, black soya bean 12kg, black rice 11kg, Chinese medicine extract 10kg, vitamin C 0.6kg, taurine 0.3kg, Se-enriched yeast 0.0012kg, steviol glycoside 0.2kg, flavoring essence 0.012kg, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
4, will mix pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 50g, be finished product.
Embodiment 5 does not add the preparation of the compound prescription nutrient powder of Chinese medicine extract:
1, respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2, take respectively shelled peanut 30kg, black soya bean 12kg, black rice 11kg, vitamin C 0.6kg, taurine 0.3kg, Se-enriched yeast 0.0012kg, steviol glycoside 0.2kg, flavoring essence 0.012kg, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
3, will mix pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 50g, be finished product.
For clinical testing.
The clinical trial of embodiment 6 compound prescription nutrient powder of the present invention:
Clinical trial divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 4 and embodiment 5 gained nutrient powder.
Experimental animal: regular grade NIH mouse, body weight 18g ± 2g, male and female half and half.
Method and result:
Figure 704037DEST_PATH_IMAGE001
by two kinds of each 50g of nutrient powder, be modulated into pasty state by the 150ml warm water respectively.
Figure 841757DEST_PATH_IMAGE002
experiment mice is divided into to two groups of male and female half and half at random, and two kinds of nutrient powder of feeding are stuck with paste respectively, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days;
Figure 428597DEST_PATH_IMAGE003
in 7 days, mouse is without death, and behavior is active, and food ration is as usual, and the hair color light, without loose dirty, is had a liking for saliva without fainting from fear, and eye, mouth, nose, ear and crissum are without abnormal secretion, without the rotten toe of docking.Select respectively 5 execution from two groups, finding of naked eye: reach the important organs such as thymus gland in the heart, liver, lung, stomach, no abnormality seen changes, and shows that two kinds of these nutrient powder are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 4 and embodiment 5 gained nutrient powder.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
Figure 182926DEST_PATH_IMAGE001
the configuration of two kinds of nutrient powder: be divided into high, medium and low three dosage groups, be respectively 200,100,50 times of edible for patients amount, be mixed into pasty state with warm water 1:1 respectively;
Figure 388779DEST_PATH_IMAGE002
experimental rats is divided into to two groups at random, the nutrition that feeding modulates is continuously respectively stuck with paste, feeding is 40 days continuously, observe animal general toxic reaction and the order of severity, check each position by operational procedure after execution, and carry out the pathological examination of the main organs such as hematology, ALT, BUN and the heart, liver, spleen, lung, kidney, stomach;
Figure 912165DEST_PATH_IMAGE003
through long-term feeding, toxic reaction does not all appear in two groups of rats.Grow good.Naked eyes outward appearance and main organs no abnormality seen.Peripheral hemogram and Serum ALT, BUN and control group relatively change without pathologic.All not significant changes such as the pathological replacement heart, liver, spleen, lung, kidney, stomach, therefore can think, through proved by pathology, two kinds of nutrition are stuck with paste animal is showed without chronic toxicity.
By above two toxicity tests, prove that the nutrient powder that the present invention makes by embodiment 4 and embodiment 5 is safe, have no side effect, can be used for clinical patients is carried out to clinical testing.
(2) clinical effectiveness experiment:
Experiment collection to easily catching a cold, volunteer 300 people of the respiratory diseases such as tracheitis, cough, male 150 people, female 150 people, be divided into tri-groups of A, B, C at random, A organizes 100 people, the men and women is 50 people respectively, age 14-61 year; B organizes 100 people, each 50 people of men and women, age 15-64 year; C organizes 100 people, each 50 people of men and women, age 14-63 year.Experimental period, from year May in March, 2013 to 2013, amounts to 60 days, catches a cold just multiple season.
1, experimental technique: the A group is taken placebo (a kind of gelatinized corn starch without any curative effect), is also every day three times, each 50g.The B group is taken food of the present invention (obtained by embodiment 4), every day three times, and each 50g, the C group is taken the obtained product of the embodiment of the present invention 5 (not adding Chinese medicine extract).It is exactly a kind of health care nutrition powder that three groups of experimental subjects all are apprised of taken.Added up respectively number of patients in 60 days.Ill rear experimental subjects will be treated normally to suffered from respiratory disease, in treatment, also will adhere to taking product of the present invention or placebo, adds up the treatment situation of suffering from the patient in two groups.
2, criterion: take the number of suffering from respiratory disease in every group and the time of ill rear healing is judge index.
3, experimental result: table 1 is in 60 days troubles state of an illness condition statistics of experiment
Figure 935484DEST_PATH_IMAGE004
Illustrate: because other reasons, the A group has 13 people to end experiment, and 87 people complete experiment; The B group has 8 people to end experiment, and 92 people complete experiment; The C group has 11 termination experiments, and 89 people complete experiment.Flu number A group has 11 people, twice, 5 people that catches a cold to catch a cold 3 times; The B group has 5 people, twice, 1 people that catches a cold to catch a cold 3 times; The C group has 9 people, twice, 3 people that catches a cold to catch a cold 3 times.Patient's mean treatment number of days is coughed two groups and is added up with flu and tracheitis pneumonia, and other respiratory diseases are oversize not at the row of statistics because of disease time.
4, interpretation: as can be seen from Table 1, in B group experimenter, the number of patients of every kind of disease is minimum, and the C group is taken second place, and the A group at most; And in the B group the number of twice flu and three times also far less than the A group, the number of C group mediates.For the treatment number of days B after ill, organize also much smaller than the A group.These presentation of results, the nutrient powder that does not add Chinese medicine extract also has auxiliary curing and strengthens immunity, but after having added the traditional Chinese medicine ingredients of seldom measuring, both synergies increase auxiliary curing and the effect that strengthens immunity greatly.In addition, A group experimenter 92 people are continuing to take in nutrient powder 60 days, and without any discomfort and side effect, proving again nutrient powder provided by the invention is safe.

Claims (8)

1. the full nutrient formulation food of five cereals for the respiratory disease edible for patients; it is characterized in that: take shelled peanut, black soya bean, black rice is raw material; add Chinese medicine extract, vitamin C, taurine, Se-enriched yeast, steviol glycoside, flavoring essence, hybrid process is made.
2. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1, it is characterized in that: the formula of described food is by weight: shelled peanut 25-35 part, black soya bean 10-15 part, black rice 8-12 part, Chinese medicine extract 8-11 part, vitamin C 0.4-0.8 part, taurine 0.2-0.4 part, Se-enriched yeast 0.001-0.0013 part, steviol glycoside 0.1-0.3 part, flavoring essence 0.01-0.014 part.
3. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1, it is characterized in that: the formula of described food is by weight: 30 parts, shelled peanut, 12 parts, black soya bean, 11 parts of black rices, 10 parts of Chinese medicine extracts, 0.6 part of vitamin C, 0.3 part of taurine, 0.0012 part of Se-enriched yeast, 0. part of steviol glycoside, 0.012 part of flavoring essence.
4. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1, is characterized in that the formula of described Chinese medicine extract is by weight: tendril-leaved fritillary bulb 11-18 part, balloonflower root 12-16 part, Chinese ephedra 8-12 part, motherwort 7-11 part, Radix Codonopsis 11-14 part, Radix Glycyrrhizae 8-12 part, cassia twig 8-12 part, root of Chinese wild ginger 7-10 part, rhizoma zingiberis 7-12 part, fruit of Chinese magnoliavine 9-11 part.
5. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1, it is characterized in that: the formula of described Chinese medicine extract is by weight: 15 parts of tendril-leaved fritillary bulb, 13 parts of balloonflower roots, 10 parts, Chinese ephedra, 9 parts of motherworts, 12 parts of Radix Codonopsis, 10 parts, Radix Glycyrrhizae, 10 parts of cassia twig, 8 parts of the roots of Chinese wild ginger, 10 parts of rhizoma zingiberis, 10 parts, the fruit of Chinese magnoliavine.
6. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1 is characterized in that the preparation method of described food comprises following steps:
1) respectively by shelled peanut, black soya bean, black rice, clean, dry, ground 80 mesh sieves, standby;
2) by the described Chinese prescription of claim 3 or 4, accurately take respectively: tendril-leaved fritillary bulb, balloonflower root, Chinese ephedra, motherwort, Radix Codonopsis, Radix Glycyrrhizae, cassia twig, the root of Chinese wild ginger, rhizoma zingiberis, the fruit of Chinese magnoliavine, pulverize respectively, mix, add the purified water of 8 times of weight, reflux and decoct 1 hour, a filters to get filtrate; The purified water that adds 6 times of weight in filter residue, then the decoction 1 hour that refluxes, b filters to get filtrate; Filtrate a and b are mixed, be Chinese medicine extract, standby;
3) by right, want 1 or 2 described formulas to take respectively shelled peanut, black soya bean, black rice, Chinese medicine extract, vitamin C, taurine, Se-enriched yeast, steviol glycoside, flavoring essence, by all raw materials except vitamin C, add purified water, be mixed into scattered paste shape, be heated to 100 ℃, keep 5 minutes, be cooled to room temperature, add vitamin C, mix;
4) by 3) gained pastel vacuum drying (temperature is not higher than 50 ℃), grind, cross 60 mesh sieves, press every bag of encapsulation of 30-70g, be finished product.
7. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1, it is characterized in that: described food can be made powdery, graininess or block food.
8. a kind of full nutrient formulation food of five cereals for the respiratory disease edible for patients as claimed in claim 1, it is characterized in that: described food can be used as the nutraceutical of auxiliary curing respiratory disease, also can be used as the health products of prevention respiratory disease.
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CN105361159A (en) * 2015-11-30 2016-03-02 济南鲁拓生物制药有限公司 Air pollution caused respiratory disease preventing caffeine health-care product and preparation method thereof
CN106805235A (en) * 2017-01-17 2017-06-09 恩施硒域传奇健康管理有限公司 A kind of full nutrition formula food suitable for respiratory disease patient
CN108651987A (en) * 2018-04-29 2018-10-16 广东伊茗药业有限公司 A kind of full nutrition formula food suitable for respiratory disease patient

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CN102783643A (en) * 2012-08-15 2012-11-21 北京惠伴康健电子商务有限公司 Fragrant-grinding five-cereal health preserving powder
CN103173319A (en) * 2013-04-15 2013-06-26 余豪 Medlar fruit wine with health care function, and preparation method thereof

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CN1092301A (en) * 1993-03-15 1994-09-21 孙恩德 Black health care dietetic treatment reinforcing agent
CN101390618A (en) * 2008-10-15 2009-03-25 王维权 Series nutrition porridge powder and production method thereof
CN101869244A (en) * 2010-06-21 2010-10-27 金勇� Method for producing puffed food with stable selenium content
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* Cited by examiner, † Cited by third party
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CN105361159A (en) * 2015-11-30 2016-03-02 济南鲁拓生物制药有限公司 Air pollution caused respiratory disease preventing caffeine health-care product and preparation method thereof
CN106805235A (en) * 2017-01-17 2017-06-09 恩施硒域传奇健康管理有限公司 A kind of full nutrition formula food suitable for respiratory disease patient
CN108651987A (en) * 2018-04-29 2018-10-16 广东伊茗药业有限公司 A kind of full nutrition formula food suitable for respiratory disease patient

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