CN103431277B - Mixed-grain total-nutrition formulation food for traumatic or surgical patients - Google Patents
Mixed-grain total-nutrition formulation food for traumatic or surgical patients Download PDFInfo
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Abstract
The invention discloses a mixed-grain total-nutrition formulation food for traumatic or surgical patients, and relates to the field of healthcare foods. The food is prepared by mixing millet, black rice, pearl barley, glutamine, whey proteins, arginine, herbal powder, glutamic acid, stevioside, edible essence and the like. Chinese herbal medicinal ingredients, various amino acids and basic nutrition elements are combined to prepare the food with nutrition healthcare and auxiliary treatment effects for patients with wounds such as open wounds, wound infection, burn injury, surgeries and abscesses. The food is simple in process, convenient to eat, good in mouth feel, good in effect and easy to popularize and apply.
Description
Technical field
The present invention relates to health food technology field, be specifically related to a kind of for wound, the edible full nutrient formulation food of patient with operation.
Background technology
Wound definition: fall servants, be subject to external force collision, weapons damage, operation, and insect and animal biting, the paathogenic factors such as boiling hot, burning, frostbite cause skin and flesh muscles and bones and internal organ injured.When after human organism's damaged, the people that immunity is strong can resist the bacteria attack of wound very soon, and wound can heal very soon; The people that immunity is poor, particularly has a delicate constitution, the long-term sick patient who has an operation again, to the invasive ability of resisting germ a little less than, once there be wound, tend to occur the infection symptoms such as pain, heating, abscess, serious can also threat to life.Now anti-inflammation drugs is numerous, and effect is also good, but tends to occur the problem of excessive use, the destruction that can cause autoimmunity system, be the resistance of self worse and worse.Due to antibiotic abuse, also can promote the evolution of bacterium in addition, produce superbacteria, unmatched bacterium etc.Cause very large harm to nature.The present invention is just based on this, invents a kind of healing after can supplemental treatment body injured and recovers, and reduces antiphlogistic, antibiotic use, and can improve the health, and conditioning blood vessels, improve patient's immunity.
Summary of the invention
The technical problem to be solved in the present invention is, manufacture a kind of full nutrient formulation food of five cereals for edible for patients such as open wound, wound infection, burn, operation, running sores, this food can play to patient the effects such as supplemental treatment, wound healing, quickening recovery.
In order to address the above problem, the present invention utilizes millet, black rice, the seed of Job's tears, is basic nutrient raw material, has strengthened high-quality protein, has added lactalbumin; Strengthened the several amino acids such as glutamine, arginine, glutamic acid, add again traditional Chinese medicine ingredients on the basis of various nutrition, carry out promoting blood circulation and removing blood stasis, remove necrosis and promote granulation, bowl spares is regulated the flow of vital energy, dysmenorrhoea is active, has further strengthened health care and adjuvant treatment effect.
The present invention is a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, is made up: millet 18-23 part, black rice 8-12 part, seed of Job's tears 8-12 part, glutamine 15-19 part, lactalbumin 12-17 part, arginine 9-13 part, traditional Chinese medicine powder 1.3-1.7 part, glutamic acid 0.02-0.04 part, steviol glycoside 0.1-0.3 part, flavoring essence 0.011-0.015 part of the raw material of following weight portion.
The present invention is a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, is preferably made up of the raw material of following weight portion: 20 parts of millets, 10 parts of black rices, 10 parts of the seeds of Job's tears, 17 parts of glutamine, 15 parts of lactalbumins, 11 parts of arginine, 1.5 parts of traditional Chinese medicine powder, 0.03 part, glutamic acid, 0.2 part of steviol glycoside, 0.013 part of flavoring essence.
The present invention is a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, and described traditional Chinese medicine powder is made up of the raw material of following weight portion: ginseng 10-14 part, Radix Angelicae Sinensis 10-14 part, myrrh 6-10 part, Radix Astragali 8-12 part, radix paeoniae rubrathe 6-10 part, Ligusticum wallichii 8-12 part, windproof 8-12 part, balloonflower root 5-9 part, bark of official magnolia 8-12 part, dried orange peel 6-10 part, cassia twig 6-10 part, root of Dahurain angelica 8-12 part, Radix Glycyrrhizae 10-14 part.
The present invention is a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, and described traditional Chinese medicine powder is preferably made up of the raw material of following weight portion: 12 parts of ginsengs, 12 parts of Radix Angelicae Sinensis, 8 parts of myrrhs, 10 parts of the Radixs Astragali, 8 parts of the radix paeoniae rubrathe, 10 parts of Ligusticum wallichiis, windproof 10 parts, 7 parts of balloonflower roots, 10 parts of the barks of official magnolia, 8 parts of dried orange peels, 8 parts of cassia twig, 10 parts of the roots of Dahurain angelica, 12 parts, Radix Glycyrrhizae.
Of the present invention a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, its preparation method comprises following processing step:
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng, Radix Angelicae Sinensis, myrrh, the Radix Astragali, the radix paeoniae rubrathe, Ligusticum wallichii, windproof, balloonflower root, the bark of official magnolia, dried orange peel, cassia twig, the root of Dahurain angelica, Radix Glycyrrhizae, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet, black rice, the seed of Job's tears, glutamine, lactalbumin, arginine, traditional Chinese medicine powder, glutamic acid, steviol glycoside, flavoring essence, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) gained scattered paste shape thing makes finished product and get final product.
Formula food of the present invention can be made powdery, granule state food, with warm water punching food, also can make block food, directly edible.
Of the present invention a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, its primary raw material is:
Millet: also claiming maize, be standing grain ancient times, is the product after millet is shelled.Except abundant irony, millet also has protein, compound vitamin B, calcareous, potassium, cellulose etc.Millet can strengthening the spleen and stomach, help is deficient and middle kidney-nourishing, except thermal detoxification.Control taste abnormal heat, gastric disorder causing nausea is vomitted, quenches one's thirst, is had loose bowels.Millet contains multiple to the useful function factor of property, energy establishing-Yang, enriching yin, aristogenesis.
Black rice: be the rice of a kind of medicine, food dual-purpose, belong to glutinous rice class.Black rice is containing protein 12 .5%, crude fat 2.7-3.8%, carbohydrate 75-84%, coarse ash 1.7-2%.The inorganic salts such as the contained manganese of black rice, zinc, copper mostly than the high 1-3 of rice doubly; More contain the special composition such as vitamin C, chlorophyll, anthocyanidin, carrotene and cardiac glycoside that rice lacks, the congee delicate fragrance boiling with black rice is glossy, soft glutinous agreeable to the taste, nutritious, there is good tonic effect, be therefore called as " rice of enriching blood ", " long-lived rice " etc.; Folks of china has saying of " meeting black must benefit ".
Modern medicine confirms, black rice has enriching yin and nourishing kidney, strengthening spleen and warming liver, strengthen the spleen and stomach, and qi and activate blood circulation, the curative effect such as nourish the liver to improve visual acuity.Often edible black rice, is conducive to that control is dizzy, dizzy, anaemia, white hair, eye illness, soreness and weakness of waist and knees, xeropulmonary cough, constipation, difficult urination, edema due to deficiency of the kidney, poor appetite, the disease such as weakness of the spleen and the stomach.
The seed of Job's tears: the kind benevolence that is grass Job's tears.The nutritive value of the seed of Job's tears is very high, is described as " king of world grass ".The seed of Job's tears can be used as grain and eats, and taste is similar with rice, and absorption easy to digest, cooks congee, does Tang Junke.Because the seed of Job's tears is nutritious, for weakness due to chronic disease, reconvalescent after being ill, old man, puerpera, children are reasonable medicinal foods, can often take.No matter for nourishing or for curing the disease, effect is comparatively mitigation all, is slightly cold and does not injure one's stomach, beneficial spleen and do not grow greasy.
Glutamine: formal name used at school 2-amino-5-carboxyl pentanamide.It is the acid amides of glutamic acid.What time following its Main Function be:
1) increasing muscle, is mainly to realize by following several respects:
For body provides essential nitrogenous source, impel myocyte's internal protein synthetic; By cell compatibilization, promote myocyte's growth and differentiation; The secretion of stimulating growth hormone, insulin and testosterone, makes body in synthetic state.
2) glutamine has forceful action.
Increase strength, improve endurance.Between moving period, the increase of body acidic metabolite makes body fluid acidifying.Glutamine has the potentiality of base of generation, thereby can reduce to a certain extent reduction or the fatigue of the locomitivity that acidic materials cause.
3) immune important fuel, can strengthen immune function.
Glutamine has important immunoregulation effect, and it is that lymphocytic emiocytosis, propagation and function thereof remain necessary.As precursor and the main energy sources of Nucleic acid, glutamine can impel mitosis and the differentiation and proliferation of lymphocyte, macrophage, and the generation of increase cytokine TNF, IL-1 etc. and the mRNA of phosphatide are synthetic.The ratio of CD4/CD8 in TLC, T lymphocyte and the circulation that exogenous glutamine can obviously increase urgent patient is provided, strengthens the immunologic function of body.
4) participate in synthesizing glutathion (a kind of important antioxidant).Improve the oxidation resistance of body.
5) the basic energy source of intestines and stomach tube chamber cell.
Maintain structure and the function of gut barrier: glutamine is the essential nutriment of intestinal mucosa cellular metabolism, and the integrality that maintains intestinal mucosa epithelial structure is played a very important role.Especially under the serious stress situation such as wound, infection, fatigue, in intestinal mucosa epithelial cell, glutamine is exhausted very soon.In the time that enteron aisle lacks food, digestive juice etc. and stimulates or lack glutamine, intestinal mucosa atrophy, fine hair is thinning, shortening even comes off, and crypts shoals, and intestinal mucosal permeability increases, and intestinal immunity is impaired.Clinical practice proves, the outer approach of intestines provides glutamine all can effectively prevent intestinal mucosa atrophy, keeps normal intestinal mucosa weight, structure and protein content, strengthens intestinal cell activity, improve intestinal immunity, reduce enteric bacteria and endotoxic transposition.
6) supplement in right amount glutamine in time and can effectively prevent the decomposition of muscle protein, and can, by the aquation of cell, increase the volume of cell, promote muscle growth.Glutamine or a few can promote one of amino acid that growth hormone discharges.Research shows, oral 2 grams of glutamine just can make the level of growth hormone improve 4 times, and insulin and testosterone secretion are increased, thereby strengthens the synthesis of muscle.
Studies show that, supplement in right amount glu famine in time and can effectively prevent the decomposition of muscle protein, and can, by the aquation of cell, increase the volume of cell, promote muscle growth.Glutamine or a few can promote one of amino acid that growth hormone discharges.Separately have research to think, glutamine has the effect that muscle glycogen is assembled.
Lactalbumin: be a kind of protein being present in nearly all mammal milk, formed by 123 amino acid residues, its amino acid sequence and stereochemical structure all with lysozyme homology, be a subunit of lactose synthase.Lactalbumin is called as the king of albumen, is a kind of protein extracting from milk, have to be of high nutritive value, absorption easy to digest, to contain the features such as various active composition, and be one of generally acknowledged human body good protein replenishers.
Arginine: formal name used at school: (S)-2-Amino-5-guanidinopentanoic acid.A kind of polarity alpha amino acid that contains guanidine radicals of aliphatic alkalescence.It mainly contains following effect:
1) function in protein
The ability of arginic molecular structure, CHARGE DISTRIBUTION and formation multiple hydrogen bonding, can be combined with the molecule with negative electrical charge it.Therefore, arginine, in the periphery of protein, can produce interaction under charged environment.In protein, victory peptide spermine acid deiminase can change into citrulling by arginine.And protein methyltranferase can methylate arginine.
2) as precursor
Arginine is the direct precursor of nitric oxide, urea, ornithine and flesh butylamine, is the important essence of synthetic muscle element, and is used as the synthetic of polyamine, citrulling and glutamine.As nitric oxide production precursor, arginine can be assisted vasodilator.Asymmetric Dimethylarginine (ADMA) can constrain nitric oxide production chemical action, so ADMA is considered to the mark of vascular diseases, just as the symbol that arginine is healthy endothelial layer.
3) constrain virus replication
Cell is cultivated research and is pointed out, in the time of (in vitro) lysine outside organism and arginic ratio deflection lysine, can constrain copying of virus.Effect in treatment is but unknown, but edible arginine can affect the effectiveness of injection lysine.
4) nutritional supplement
Arginine is that a constituent in ornithine circulation has extremely important physiological function.Eat arginine more, can increase the activity of arginase in liver, so contribute to the ammonia in blood change urea into and excrete out, arginine is to hyperammonemia, and liver dysfunction etc. are all powerful.
Traditional Chinese medicine powder: the Chinese prescription of the traditional Chinese medicine powder in food formula of the present invention is on the basis of traditional recipe, meticulously allocates and forms through clinical testing, and this prescription Chinese medicine used is respectively:
Ginseng: property is flat, sweet, the micro-hardship of taste, tepor.Return spleen, lung channel, the heart channel of Hang-Shaoyin.Reinforce vital energy, multiple arteries and veins is admittedly de-, reinforces the spleen to benefit the lung, promote the production of body fluid to quench thirst, and the intelligence development of calming the nerves.Cure mainly that internal lesion caused by overexertion is deficient, food less, burnout, gastric disorder causing nausea tell that food, stool lingering diarrhea, void cough that syndrome characterized by dyspnea, spontaneous perspiration are cruelly de-, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's slowly frightened and for a long time void not again, the disease of all qi-blood-body fluid deficiencies.
Radix Angelicae Sinensis: taste is sweet; Pungent; Bitter; Warm in nature.Return liver; The heart; The spleen channel.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Cure mainly all cards of the deficiency of blood; Irregular menstruation; Through closing; Dysmenorrhoea; Abdominal mass knot is poly-; Uterine bleeding; Asthenia cold abdominalgia; Impotence numbness; Numbness; Intestines are dry just difficult; Heavy after dysentery characterized by blood in the stool; Ulcer sores; Injury from falling down.
Myrrh: bitter, pungent, property is flat.Enter liver, spleen, the heart, kidney channel.Loose blood detumescence, analgesic therapy myogenic.Take for a long time relaxing muscles and tendons film, promoting blood circulation, permanent tooth tooth, long beard and hair.
The Radix Astragali: property is sweet, temperature.Return lung, the spleen channel.There is invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, effect of expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, the sinking of qi of middle-jiao, rushes down prolapse of the anus for a long time, the uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult bursts, and burst and do not hold back for a long time, flaccidity of limbs due to deficiency of blood Huang, interior heat is quenched one's thirst; Chronic nephritis albuminuria, diabetes.
The radix paeoniae rubrathe: bitter, cold nature.Return Liver Channel.Clearing heat and cooling blood; Promoting blood circulation.Main febrile virulent maculae; Hematemesis and epistaxis; Discharging fresh blood stool; Red eye, swell pain; The carbuncle sore that swells; Amenorrhoea; Dysmenorrhoea; Collapse band stranguria with turbid discharge; The stagnant hypochondriac pain of the stasis of blood; Hernia lump in the abdomen is gathered; Injury from falling down.For febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, through closing dysmenorrhoea, abdominal mass stomachache, injury from falling down, the carbuncle sore that swells.
Ligusticum wallichii: taste is pungent, warm in nature.Return liver, courage, pericardium channel.Promoting blood circulation; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Cure mainly headache; Irregular menstruation; Through closing dysmenorrhoea; The stagnant raw meat pain of the stasis of blood in postpartum; Abdominal mass lump; Pain in chest and hypochondrium; Have a headache dizzy; Wind-cold-dampness arthralgia; Traumatic injury; Ulcer sores.
Windproof: taste is pungent; Sweet; Slightly warm in nature.Return urinary bladder channel; Lung channel; The spleen channel; Liver Channel.Expel pathogenic wind from the body surface, removing dampness to relieve pain, spasmolysis, antipruritic.Cure mainly and catch cold; Headache bodily pain; Arthralgia due to wind-dampness; Joint is ached; Stomachache is had loose bowels; Discharging fresh blood stool; Lockjaw; Rubella itch; Sore from the beginning of.
Balloonflower root: bitter; Pungent; Property is put down.Enter lung channel.A surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, sharp the five internal organs, fill blood, mend the exhaustion or lesion of the five internal organs, foster the spirit of nobility.Cure mainly coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache, aphthae, red eye, swell pain, uroschesis.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, hoarsen, lung carbuncle pyemesis, sore purulence does not become to burst.
The bark of official magnolia: bitter; Pungent; Warm in nature.Return through the spleen channel; Stomach warp; Large intestine channel.Promoting the circulation of qi disappears long-pending; Eliminating dampness is except full; Relieving asthma.Cure mainly stagnation of QI due to dyspepsia; Abdominal distention constipation; Damp retention in middle-jiao, gastral cavity ruffian is vomited and diarrhoea; Phlegm is stopped up the circulation of vital energy in the wrong direction; Fullness sensation in chest is breathed with cough.
Dried orange peel: bitter, pungent, warm in nature.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For chest gastral cavity turgor, food is few vomits and diarrhoea, coughing with a lot of sputum.
Cassia twig: taste is pungent, sweet, warm in nature.The thoughts of returning home, lung, urinary bladder channel.Sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, helps yang transforming qi, making the adverse-rising QI downwards.
The root of Dahurain angelica: warm in nature, taste is pungent, micro-sweet.Enter lung, spleen, stomach warp.For Yangming Channel guiding drug.Dispel rheumatism; Logical surreptitiously pain relieving; Detumescence and apocenosis.Main cold headache; Pain in the supra-orbital bone; Toothache; Nasal obstruction; Nasosinusitis; Wet victory is rushed down for a long time; Women leukorrhea; Ulcer sores; Venomous snake bite.For cold headache, pain in the supra-orbital bone, nasal obstruction, nasosinusitis, toothache, leukorrhea, sore swells and ache.
Radix Glycyrrhizae: taste is sweet, property is flat, nontoxic.Cure mainly vital organs of the human body fever and chills perverse trend, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Raw purging intense heat heat, the ripe use exterior cold of fall apart of use, goes pharyngalgia, removes heat symptoms caused by an exopathgen, delays healthy tendency, yin-nourishing blood, tonifying spleen and stomach, moistening lung.
Glutamic acid: 2-amino-5-carboxyl valeric acid.Form one of 20 kinds of common alpha amino acids of protein.Glutamic acid can be in medicine, because glutamic acid is one of amino acid forming in protein, although it is not the necessary amino acid of human body, it can be used as carbon nitrogen nutrition and organism metabolism, has higher nutritive value.After glutamic acid is absorbed by the body, easy and blood ammonia forms paddy acyl ammonia, can remove the toxic action of ammonia in metabolic process, thereby can prevent and treat hepatic coma, and protection liver, is the ancillary drug of patients with liver diseases.Brain tissue can only be oxidized glutamic acid, and can not be oxidized other amino acid, therefore glutamine can be used as the energy matter of brain tissue, improves and maintains cerebral function.Glutamic acid is as nerve center and corticocerebral tonic, for treating cerebral concussion or neurotrosis, epilepsy and mentally retarded child all being had to certain curative effect.
Steviol glycoside: be a kind of sucrose succedaneum, can not increase in the situation of heat, increase the sweet taste of food.
Compared with prior art, disclosed by the invention a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, there is following characteristics and significantly technological progress:
1, the present invention is compounded with traditional Chinese medicine ingredients, several amino acids and basic nutrient first, makes a kind of food to the nutritious health cares of body trauma patient such as open wound, wound infection, burn, operation, running sore and adjuvant treatment efficacy.Through verification, also do not have at present like product to occur.
2, grope through repetition test, study intensively and mix composition of raw materials of the present invention and Chinese prescription, the food making by this formula, the protein of its basic nutrient, strengthening and amino acid also have traditional Chinese medicine ingredients to complement each other, act synergistically, and show beat all technique effect.See embodiment 8.
3, food of the present invention can be for the supplemental treatment of the body trauma patients such as open wound, wound infection, burn, operation, running sore, and this food technology is simple, instant edible, mouthfeel is good, effect is good.
Detailed description of the invention
The preparation of embodiment 1 nutrient powder of the present invention
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng 100g, Radix Angelicae Sinensis 100g, myrrh 60g, Radix Astragali 80g, radix paeoniae rubrathe 60g, Ligusticum wallichii 80g, windproof 80g, balloonflower root 50g, bark of official magnolia 80g, dried orange peel 60g, cassia twig 60g, root of Dahurain angelica 80g, Radix Glycyrrhizae 100g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet 18kg, black rice 8kg, seed of Job's tears 8kg, glutamine 15kg, lactalbumin 12kg, arginine 9kg, traditional Chinese medicine powder 1.3kg, glutamic acid 0.02kg, steviol glycoside 0.1kg, flavoring essence 0.011kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 2 nutrient powder of the present invention
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng 140g, Radix Angelicae Sinensis 140g, myrrh 100g, Radix Astragali 120g, radix paeoniae rubrathe 100g, Ligusticum wallichii 120g, windproof 120g, balloonflower root 90g, bark of official magnolia 120g, dried orange peel 100g, cassia twig 100g, root of Dahurain angelica 120g, Radix Glycyrrhizae 140g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet 23kg, black rice 12kg, seed of Job's tears 12kg, glutamine 19kg, lactalbumin 17kg, arginine 13kg, traditional Chinese medicine powder 1.7kg, glutamic acid 0.04kg, steviol glycoside 0.3kg, flavoring essence 0.015kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 3 nutrient powder of the present invention
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng 110g, Radix Angelicae Sinensis 110g, myrrh 70g, Radix Astragali 90g, radix paeoniae rubrathe 70g, Ligusticum wallichii 90g, windproof 90g, balloonflower root 60g, bark of official magnolia 90g, dried orange peel 70g, cassia twig 70g, root of Dahurain angelica 90g, Radix Glycyrrhizae 110g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet 19kg, black rice 9kg, seed of Job's tears 9kg, glutamine 16kg, lactalbumin 13kg, arginine 10kg, traditional Chinese medicine powder 1.4kg, glutamic acid 0.025kg, steviol glycoside 0.15kg, flavoring essence 0.012kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 4 nutrient powder of the present invention
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng 130g, Radix Angelicae Sinensis 130g, myrrh 90g, Radix Astragali 110g, radix paeoniae rubrathe 90g, Ligusticum wallichii 110g, windproof 110g, balloonflower root 80g, bark of official magnolia 110g, dried orange peel 90g, cassia twig 90g, root of Dahurain angelica 110g, Radix Glycyrrhizae 130g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet 22kg, black rice 11kg, seed of Job's tears 11kg, glutamine 18kg, lactalbumin 16kg, arginine 12kg, traditional Chinese medicine powder 1.6kg, glutamic acid 0.03kg, steviol glycoside 0.2kg, flavoring essence 0.014kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 5 nutrient powder of the present invention
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng 130g, Radix Angelicae Sinensis 110g, myrrh 90g, Radix Astragali 90g, radix paeoniae rubrathe 90g, Ligusticum wallichii 90g, windproof 110g, balloonflower root 60g, bark of official magnolia 110g, dried orange peel 70g, cassia twig 90g, root of Dahurain angelica 90g, Radix Glycyrrhizae 130g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet 22kg, black rice 9kg, seed of Job's tears 11kg, glutamine 16kg, lactalbumin 16kg, arginine 10kg, traditional Chinese medicine powder 1.6kg, glutamic acid 0.02kg, steviol glycoside 0.2kg, flavoring essence 0.012kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
The preparation of embodiment 6 nutrient powder of the present invention
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take each taste Chinese medicine by described formula above: ginseng 120g, Radix Angelicae Sinensis 120g, myrrh 80g, Radix Astragali 100g, radix paeoniae rubrathe 80g, Ligusticum wallichii 100g, windproof 100g, balloonflower root 70g, bark of official magnolia 100g, dried orange peel 80g, cassia twig 80g, root of Dahurain angelica 100g, Radix Glycyrrhizae 120g, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) accurately take various raw meal by described formula above: millet 20kg, black rice 10kg, seed of Job's tears 10kg, glutamine 17kg, lactalbumin 15kg, arginine 11kg, traditional Chinese medicine powder 1.5kg, glutamic acid 0.03kg, steviol glycoside 0.2kg, flavoring essence 0.013kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
Embodiment 7 does not add the preparation of the nutrient powder of the present invention of traditional Chinese medicine powder
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) accurately take various raw meal by described formula above: millet 20kg, black rice 10kg, seed of Job's tears 10kg, glutamine 17kg, lactalbumin 15kg, arginine 11kg, glutamic acid 0.03kg, steviol glycoside 0.2kg, flavoring essence 0.013kg, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
3) by 2) oven dry of gained scattered paste shape thing, pulverize, levigate, cross 80 mesh sieves, 50g/ bag packaging, is finished product.
The clinical testing of 8 product nutrient powder of embodiment
Clinical testing is divided into two parts, and Part I is acute and chronic toxicity test, and Part II is clinical effectiveness experiment.
(1) animal acute toxicity and chronic toxicity experiment:
Preliminary experiment shows, nutrient powder of the present invention, and toxicity is very little, cannot measure LD
50, therefore, according to maximum dosage feeding.
1, animal acute toxicity test
Medicine: the embodiment of the present invention 6 and embodiment 7 gained nutrient powder.
Experimental animal: regular grade NIH mouse, body weight 18g ± 2g, male and female half and half.
Method and result:
1) by two kinds of each 50g of nutrient powder, be modulated into pasty state by 150ml warm water respectively.
2) experiment mice is divided at random to two groups of male and female half and half, two kinds of nutrient powder of feeding are stuck with paste respectively, volume 2ml/10g body weight, and close observation 8h also notes down, and continues to observe 7 days;
3) in 7 days, mouse is without death, and behavior is active, and food ration is as usual, and hair color light, without loose dirty, is had a liking for saliva without fainting from fear, and eye, mouth, nose, ear and crissum are without abnormal secretion, without the rotten toe of docking.From two groups, select respectively 10 execution, finding of naked eye: in the heart, liver, lung, stomach and the important organ such as thymus gland, no abnormality seen changes, and shows that two kinds of these nutrient powder are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 6 and embodiment 7 gained nutrient powder.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
1) configuration of two kinds of nutrient powder: be divided into high, medium and low three dosage groups, be respectively 240,120,60 times of edible for patients amount, be mixed into pasty state with warm water 1:1 respectively;
2) experimental mouse is divided into two groups at random, the nutrition that feeding modulates continuously is respectively stuck with paste, feeding 60 days continuously, observe animal general toxic reaction and the order of severity, after execution, check each position by operational procedure, and carry out hematology, the pathological examination of the main organs such as ALT, BUN and the heart, liver, spleen, lung, kidney, stomach;
3) through long-term feeding, all there is not toxic reaction in two groups of rats.Physically well develop.Naked eyes outward appearance and main organs no abnormality seen.Peripheral hemogram and Serum ALT, BUN and control group relatively change without pathologic.All not significant changes such as the pathological replacement heart, liver, spleen, lung, kidney, stomach, therefore, think through proved by pathology, two kinds of nutrient powder all show without chronic toxicity animal.
By above two toxicity tests, prove that the nutrient powder that the present invention makes by embodiment 6 and embodiment 7 is safe, have no side effect, can be by edible for patients.
(2) clinical effectiveness test
1, experimental subjects
Wounded patient 180 people, all from same hospital, wherein male 132 people, female 68 people, slight wound is totally 120 people, and severely injured 60 people are divided into tri-groups of A, B, C at random, every group of 60 people, slight wound 40 people, severely injured 20 people; A organizes 35.6 years old mean age, and B organizes 37.1 years old mean age, and C organizes 34.2 years old mean age.
2, test method
A, B, tri-groups of C all adopt normal trauma care mode to treat injured afterwards.Organize as a control group with A, except normal therapeutic, take placebo (a kind of and similar starch of product of the present invention, without any therapeutic action); B group, except normal therapeutic, is taken the embodiment of the present invention 6 gained nutrient powder; C group, except normal therapeutic, is taken the embodiment of the present invention 7 gained nutrient powder.The dose of three groups is 50g/ time, and three times on the one, be 5 hours interval time.Slight wound patient starts to take from injured, and severely injured patient took after injured 3 days, continues to use until wound heals completely.
3, evaluation criterion
For injured object, whether wound infects, infection symptoms disappears speed, wound healing speed, more after scar size etc., can be used as the judgment criteria of the drug effect in injury treatment process.Therefore, this experiment just adopts these standards as the judgment criteria of weighing nutrient powder effect of the present invention.
4, experimental result: through the tracing observation to all experimental subjects, show that experimental result is in table 1.
Table 1 nutrient powder experimental result of the present invention
Illustrate: because of wound severe infection (occurring whole body heating) person, all can occur the symptom of wound low-grade infection person (the red and swollen pain of wound), in this table statistics, all be not counted in the number of low-grade infection; The average number of days of wound healing refers to wound surface healing, scabs, instead of refers to wound recovery from illness, because severely injured patient is often injured in the sinews or bones, the course of disease is very long, cannot add up.
5, interpretation of result
As can be seen from Table 1, B group patient treatment situation is significantly better than two other group, although C group is not added traditional Chinese medicine ingredients, but still there is certain adjuvant treatment effect, this explanation, the protein of traditional Chinese medicine ingredients and strengthening, amino acid also have synergy have well occurred between basic nutrient, have shown beat all technological achievement.
Claims (6)
1. for wound, the edible full nutrient formulation food of five cereals of patient with operation, it is characterized in that being made by the raw material of following weight portion: millet 18-23 part, black rice 8-12 part, seed of Job's tears 8-12 part, glutamine 15-19 part, lactalbumin 12-17 part, arginine 9-13 part, traditional Chinese medicine powder 1.3-1.7 part, glutamic acid 0.02-0.04 part, steviol glycoside 0.1-0.3 part, flavoring essence 0.011-0.015 part;
Described traditional Chinese medicine powder is made up of the raw material of following weight portion: ginseng 10-14 part, Radix Angelicae Sinensis 10-14 part, myrrh 6-10 part, Radix Astragali 8-12 part, radix paeoniae rubrathe 6-10 part, Ligusticum wallichii 8-12 part, windproof 8-12 part, balloonflower root 5-9 part, bark of official magnolia 8-12 part, dried orange peel 6-10 part, cassia twig 6-10 part, root of Dahurain angelica 8-12 part, Radix Glycyrrhizae 10-14 part.
2. as claimed in claim 1 a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, it is characterized in that being made by the raw material of following weight portion: 20 parts of millets, 10 parts of black rices, 10 parts of the seeds of Job's tears, 17 parts of glutamine, 15 parts of lactalbumins, 11 parts of arginine, 1.5 parts of traditional Chinese medicine powder, 0.03 part, glutamic acid, 0.2 part of steviol glycoside, 0.013 part of flavoring essence.
3. as claimed in claim 1 or 2 a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation, it is characterized in that described traditional Chinese medicine powder is made up of the raw material of following weight portion: 12 parts of ginsengs, 12 parts of Radix Angelicae Sinensis, 8 parts of myrrhs, 10 parts of the Radixs Astragali, 8 parts of the radix paeoniae rubrathe, 10 parts of Ligusticum wallichiis, windproof 10 parts, 7 parts of balloonflower roots, 10 parts of the barks of official magnolia, 8 parts of dried orange peels, 8 parts of cassia twig, 10 parts of the roots of Dahurain angelica, 12 parts, Radix Glycyrrhizae.
4. a kind of preparation method for the edible full nutrient formulation food of five cereals of wound, patient with operation as described in claim 1, is characterized in that comprising following processing step:
1) millet, black rice, the seed of Job's tears are cleaned, dry, ground, cross 100 mesh sieves, for subsequent use;
2) take each taste Chinese medicine: ginseng, Radix Angelicae Sinensis, myrrh, the Radix Astragali, the radix paeoniae rubrathe, Ligusticum wallichii, windproof, balloonflower root, the bark of official magnolia, dried orange peel, cassia twig, the root of Dahurain angelica, Radix Glycyrrhizae, cut into slices respectively, dry, grind, cross 80 mesh sieves, mix, be traditional Chinese medicine powder, for subsequent use;
3) take various raw meal: millet, black rice, the seed of Job's tears, glutamine, lactalbumin, arginine, traditional Chinese medicine powder, glutamic acid, steviol glycoside, flavoring essence, mix, add purified water furnishing scattered paste shape, be heated to 100 DEG C, keep 5 minutes, cooling;
4) by 3) gained scattered paste shape thing makes finished product and get final product.
5. a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation as described in as arbitrary in claim 1 or 2, is characterized in that: described formula food can be made powdery, graininess or bulk.
6. a kind of for wound, the edible full nutrient formulation food of five cereals of patient with operation as described in as arbitrary in claim 1 or 2, is characterized in that: described formula food can be for the supplemental treatment of body trauma patient and nutrition and health care.
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