CN117441892A - Food with digestion promoting and stagnation removing effects and preparation method thereof - Google Patents
Food with digestion promoting and stagnation removing effects and preparation method thereof Download PDFInfo
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- CN117441892A CN117441892A CN202311504839.4A CN202311504839A CN117441892A CN 117441892 A CN117441892 A CN 117441892A CN 202311504839 A CN202311504839 A CN 202311504839A CN 117441892 A CN117441892 A CN 117441892A
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- food
- fructus
- rhizoma polygonati
- food stagnation
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Classifications
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- A—HUMAN NECESSITIES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
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- A23F3/00—Tea; Tea substitutes; Preparations thereof
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The invention discloses a food with the effects of promoting digestion and removing food stagnation, which is prepared from the following raw materials in parts by weight: 20-30 parts of hawthorn, 15-25 parts of radish seed, 18-22 parts of emblic leafflower fruit, 12-18 parts of artificially planted ginseng, 25-35 parts of Chinese yam, 18-22 parts of rhizoma polygonati, 15-25 parts of malt, 8-12 parts of chicken's gizzard-membrane, 20-30 parts of medlar, 15-25 parts of sea buckthorn, 18-22 parts of dried orange peel and 10-20 parts of poria cocos, and the preparation method of the hawthorn fruit tea is disclosed.
Description
Technical Field
The application relates to the technical field of foods, in particular to a food with the effects of promoting digestion and removing food stagnation and a preparation method thereof.
Background
Food stagnation refers to a condition in the digestive system where food is accumulated in the digestive tract before it is stopped. With the improvement of living standard and the acceleration of living rhythm, unhealthy eating modes occur, and when people eat excessively, eat excessively fast or have poor digestive functions, food is difficult to pass smoothly in the digestive tract, or children eat excessively. In this case, food may remain in the stomach or intestinal tract, resulting in the occurrence of symptoms such as dyspepsia, abdominal distention, and gastralgia. Food stagnation may also cause other health problems such as constipation, gastric acid regurgitation, gastric ulcers, etc.
The reasons for food stagnation are various, including poor eating habits, excessive stress, digestive system diseases and the like. Some common foods that cause food stagnation include high fat, high fiber, spicy or fried foods, and stimulating drinks such as coffee, alcohol, etc.
The clinical symptoms of food stagnation include poor appetite, indigestion, abdominal distending pain, refusal of pressing, eructation, acid regurgitation, anorexia, vomiting, pain, diarrhea, constipation, loose stool, thick and greasy tongue coating and slippery pulse. The traditional Chinese medicine composition is mainly used for children, and when the children eat and drink in a violent way, have food stagnation and are weak in appetite, or eat oil in a sweet and greasy way, or are spicy, the generated damp-heat is accumulated in the stomach and intestine, and the stomach and intestine can be damaged when the cold stops and the internal resistance occurs, namely viscera are injured, and the qi of the viscera is not reduced, so that abdominal pain occurs. Laxatives are used blindly, which is easy to hurt healthy qi. Chronic abuse of laxatives can cause mucosal pigmentation in the colon leading to darkening of the colon to form a colonic melanosis, a benign, self-restorable, non-inflammatory bowel disease. The colon is seen to be blackened to different degrees under the enteroscope, and the patients mainly show digestive tract symptoms such as constipation, abdominal distension, diarrhea, abdominal pain and the like.
Disclosure of Invention
The food with the effect of promoting digestion and removing food stagnation provided by the invention has the advantages of good treatment of food stagnation, obvious effect, safety and reliability.
In order to achieve the above purpose, the technical scheme of the invention is as follows:
a food with the effects of promoting digestion and removing food stagnation is prepared from the following raw materials in parts by weight: 20-30 parts of hawthorn, 15-25 parts of radish seed, 18-22 parts of emblic leafflower fruit, 12-18 parts of artificially planted ginseng, 25-35 parts of Chinese yam, 18-22 parts of rhizoma polygonati, 15-25 parts of malt, 8-12 parts of chicken's gizzard-membrane, 20-30 parts of medlar, 15-25 parts of sea buckthorn, 18-22 parts of dried orange peel and 10-20 parts of poria cocos.
The food with the effects of promoting digestion and removing food stagnation is prepared from the following raw materials in parts by weight: 20-25 parts of hawthorn, 20-25 parts of radish seed, 18-20 parts of emblic leafflower fruit, 15-18 parts of artificially planted ginseng, 25-30 parts of Chinese yam, 20-22 parts of rhizoma polygonati, 15-20 parts of malt, 10-12 parts of chicken's gizzard-membrane, 20-25 parts of medlar, 20-25 parts of sea buckthorn, 18-20 parts of dried orange peel and 15-20 parts of poria cocos.
The food with the effects of promoting digestion and removing food stagnation is prepared from the following raw materials in parts by weight: 25 parts of hawthorn, 20 parts of radish seed, 20 parts of phyllanthus emblica, 15 parts of artificially planted ginseng, 30 parts of Chinese yam, 20 parts of rhizoma polygonati, 20 parts of malt, 10 parts of chicken's gizzard-membrane, 25 parts of medlar, 20 parts of sea buckthorn, 20 parts of dried orange peel and 15 parts of poria cocos.
The food with the effects of promoting digestion and removing food stagnation is prepared from the following raw materials in parts by weight: 20 parts of hawthorn, 25 parts of radish seed, 18 parts of emblic leafflower fruit, 18 parts of artificially planted ginseng, 25 parts of Chinese yam, 22 parts of rhizoma polygonati, 15 parts of malt, 12 parts of chicken's gizzard-skin, 20 parts of medlar, 25 parts of sea buckthorn, 18 parts of dried orange peel and 20 parts of poria cocos.
The food with the effects of promoting digestion and removing food stagnation is prepared from the following raw materials in parts by weight: 30 parts of hawthorn, 15 parts of radish seed, 22 parts of emblic leafflower fruit, 12 parts of artificially planted ginseng, 35 parts of Chinese yam, 18 parts of rhizoma polygonati, 25 parts of malt, 8 parts of chicken's gizzard-membrane, 30 parts of medlar, 15 parts of sea buckthorn, 22 parts of dried orange peel and 10 parts of poria cocos.
The preparation method of the food with the effects of promoting digestion and removing food stagnation comprises the following steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into coarse powder, adding 8-12 times of water, decocting for 2 times and 1-2 hr each time, mixing extractive solutions, filtering, concentrating under reduced pressure to obtain soft extract with relative density of 1.20-1.28 at 60deg.C, spray drying, and making into granule.
The preparation method of the food with the effects of promoting digestion and removing food stagnation comprises the following steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae and Poria at 60-80deg.C, pulverizing into coarse powder with 15-30 mesh sieve, and making into teabag.
The preparation method of the food with the effects of promoting digestion and removing food stagnation comprises the following steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into coarse powder, adding 8-12 times of water, decocting for 1-2 hr each time, mixing extractive solutions, filtering, concentrating under reduced pressure to obtain soft extract with relative density of 1.20-1.28 at 60deg.C, spray drying, and making into tablet.
The preparation method of the food with the effects of promoting digestion and removing food stagnation comprises the following steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into fine powder of 80-120 mesh, adding water, making into pill, making into 4-5mm pill, and drying.
The food with the effects of promoting digestion and removing food stagnation is applied to preparing food for eliminating food stagnation.
The fructus crataegi is dried mature fruit of Crataegus pini, natiida Bge, var. MajorN.E.Br. or Crataegus pini, natifida Bge. Harvesting in autumn, slicing, and drying. Sour and sweet in nature and slightly warm. It enters spleen, stomach and liver meridians. Promoting digestion, invigorating stomach, promoting qi circulation, removing blood stasis, eliminating turbid pathogen, and reducing blood lipid. Can be used for treating food stagnation, gastric distention, diarrhea, abdominal pain, blood stasis amenorrhea, puerperal blood stasis, thoracalgia, chest pain, hernia pain, and hyperlipidemia.
Radish seed is a dried mature seed of radish Raphanus sativus L. The plants are cut and dried in the sun when the fruits are ripe in summer, seeds are rubbed out, impurities are removed, and then the plants are dried in the sun. Pungent, sweet and flat in nature. Enter lung, spleen and stomach meridians. Promote digestion and remove distention, reduce qi and resolve phlegm. Is used for treating food stagnation, abdominal distention and pain, constipation, diarrhea due to accumulation of food stagnation, phlegm accumulation, asthma and cough.
Phyllanthus emblica perennial arbor plants of Phyllanthus genus of Euphorbiaceae family. Emblic leafflower fruit is recorded in books of China calendar generation, and is used as a medicine in Ben Cao Shi Yi (materia Medica for picking up body fluid, quenching thirst, moistening lung, resolving phlegm, treating cough and sore throat, relieving globefish poisoning, etc.
The artificially planted ginseng has sweet and slightly bitter taste and slightly warm nature, enters spleen and lung channels, and has the effects of reinforcing primordial qi, reinforcing spleen and benefiting lung, promoting fluid production, soothing nerves and improving intelligence. Is used for treating qi deficiency, hypofunction of pulse, spleen qi deficiency, depression of middle-jiao, asthma and cough, short breath and debilitation, thirst due to body fluid deficiency, consumptive heat and thirst, insomnia and amnesia, palpitation, sallow complexion due to blood deficiency, sexual impotence, cold womb, etc.
The rhizoma Dioscoreae is dried rhizome of Dioscorea opposita Thunb of Dioscoreaceae. Digging for 11-12 months, cutting off root, cleaning soil, scraping off the outer skin with a bamboo knife, and sun-drying or oven-drying to obtain rhizoma Dioscoreae. Coarse Mao Shanyao is selected, soaked in clear water, heated slightly, covered with cotton quilt, moistened and thoroughly mixed, then put on a wood board to be kneaded into a cylinder, cut the two ends well, dried in the sun and polished to obtain the rhizoma dioscoreae. The main functions are as follows: invigorating spleen, tonifying lung, strengthening kidney, and replenishing essence. For diarrhea due to spleen deficiency, chronic dysentery, cough due to consumptive disease, diabetes, spermatorrhea, leukorrhagia, frequent urination. Spleen and stomach tonifying, body fluid generating, lung nourishing, kidney tonifying and seminal emission astringing. Can be used for treating spleen deficiency, anorexia, chronic diarrhea, asthma and cough due to lung deficiency, spermatorrhea due to kidney deficiency, leukorrhagia, frequent urination, and diabetes due to deficiency heat. Bran-fried yam can invigorate spleen and stomach. It can be used for treating spleen deficiency, anorexia, diarrhea, loose stool, and leukorrhagia. (1) Book of changes: in the main injury, deficiency is reinforced, cold and heat evil is removed, middle energizer is reinforced, strength is improved, muscles are grown, and the hearing and eyesight are improved after long-term taking. (2) The miscellaneous records: the head and face wind, the head wind (first head wind') is dizzy, downbearing qi, stopping lumbago, treating consumptive disease, emaciation, filling five viscera, relieving dysphoria and heat, and strengthening key. (3) Drug Property theory (L): it is used for treating deficiency of the body, and has effects in invigorating five fatigue and seven injuries, removing cold wind, relieving lumbago, relieving heart-mind, invigorating heart-qi, and relieving deficiency of the body. (4) Diet therapy materia Medica: for headache, it helps to strengthen yin. (5) Japanese Sunji (Japanese Subtu) grass: has effects in strengthening tendons and bones, tranquilizing mind, and relieving amnesia. (6) Zhu Jong: raw and smashed and attached to hard toxin can dispel. (7) Typhoid implications (Shang-Cold implication): deficiency of the nourishment, clearing deficiency heat. (8) Compendium, compendium: tonifying kidney-qi, strengthening spleen and stomach, stopping diarrhea, resolving phlegm and saliva, and moistening skin and hair.
Rhizoma Polygonati is dried rhizome of Polygonatum kingianum, polygonatum sibiricum, or Polygonatum cyrtonema of Liliaceae. The Chinese medicinal composition has the effects of tonifying, invigorating spleen and stomach, and relieving symptoms such as listlessness, debilitation, soreness of waist and knees, spermatorrhea, and the like. Rhizoma Polygonati also has effects of invigorating kidney and replenishing vital essence, and can be used for treating alopecia, premature graying of beard and hair, dizziness and tinnitus caused by kidney essence and yin deficiency. Rhizoma Polygonati can also strengthen tendons and bones and enhance immunity by frequent administration, thereby maintaining the health state of human body. Besides, the rhizoma polygonati can protect the heart vessels, and is relatively suitable for patients with myocardial ischemia and cerebral ischemia.
The malt is obtained by germinating and drying mature fruit of Hordeum vulgare L. Soaking wheat grains in water, maintaining proper temperature and humidity, and sun drying or low temperature drying when the buds grow to about 0.5 cm. Promoting qi circulation, resolving food stagnation, invigorating spleen, stimulating appetite, promoting lactation and relieving distention. Can be used for treating dyspepsia, abdominal distention and pain, spleen deficiency, anorexia, galactostasis, breast pain, and female weaning.
The endothelium corneum Gigeriae Galli is the inner wall of dry sandbag of pheasant fowl Gallusgallusdomesticus Brisson. After killing chicken, the chicken gizzard is taken out, the inner wall is immediately peeled off, and the chicken gizzard is cleaned and dried. Sweet in nature and flat in flavor. Enter spleen, stomach, small intestine and bladder meridians. Stomach invigorating, digestion promoting, nocturnal emission stopping, stranguria treating, and calculus removing effects. Can be used for treating dyspepsia, emesis, dysentery, infantile malnutrition, enuresis, spermatorrhea, stranguria due to stone, and hypochondriac pain due to gallbladder distention.
The fructus Lycii is mature fruit of Lycium barbarum of Solanaceae. Picking the ripe summer and autumn fruits, removing the fruit stalks, airing in a shade until the fruit peel is wrinkled, and then insolating until the outer skin is dry and hard and the pulp is soft. Can be dried by using slow fire in the presence of rain. Fructus Lycii has various health promotion effects, and is a food approved by Ministry of health for both medicine and food. Proper amount of the tea is beneficial to health, and the tea has the effects of clearing liver and improving vision when being matched with chrysanthemum and wolfberry tea. Sweet in nature and flat in nature, enters liver and kidney meridians. Nourishing liver and kidney, replenishing essence and improving eyesight.
Fructus Hippophae is deciduous shrub fruit of Elaeagnaceae. 1-2.5 m high, more thorns, strong, top-born or side-born; tender branches are brown green, old branches are black and rough; big buds, golden yellow or rust. Flowers and leaves are opened, and the flowers are hermaphroditic. Flowering period is 4-5 months, and fruit ripening period is 9-10 months. The sea buckthorn fruit is rich in nutrition, and the fruits are determined to contain active substances such as various vitamins, fatty acids, trace elements, linolin, sea buckthorn flavone, superoxide and the like and various amino acids required by human bodies. The folium Hippophae can be used for preparing health tea. In modern medical research, sea buckthorn has the effects of relieving fatigue, enhancing memory, resisting aging, strengthening physique, improving immunity, softening heart and cerebral vessels and the like.
Pericarpium Citri Tangerinae is dried mature pericarp of Citrus reticulata Blanco (Citrus reticulata Blanco) of Rutaceae and its cultivar. The medicinal materials are divided into dried orange peel and dried orange peel. Picking ripe fruits, peeling peel, and sun drying or low temperature drying. Bitter and pungent in flavor and warm in nature. Enter lung and spleen meridians. Regulate qi, invigorate spleen, dry dampness and resolve phlegm. Can be used for treating abdominal distention, anorexia, vomiting and diarrhea, cough with excessive phlegm.
Poria is the dry sclerotium of Wolf, a fungus of the Polyporaceae family, poria cocos (Schw.) co. Digging for more than 7-9 months, removing sediment after digging out, piling up for "sweating", spreading out and airing until the surface is dry, then "sweating", repeating for several times until most of internal moisture is lost, and drying in the shade, namely "Fuling Zhi"; or cutting fresh Poria into pieces according to different parts, and drying in the shade, which are called "Poria block" and "Poria tablet", respectively. Sweet and light in taste and neutral in nature. It enters heart, lung, spleen and kidney meridians. Induce diuresis and excrete dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm retention, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae and Poria are all food and medicine, and are safe and reliable.
Song Daichen the cloud is not selected in the theory of three cause and extremely one disease pattern and the internal and external cause free: the recipe includes "treating food intake chongdo, chong cheese, rare land and water, preserved fruit with impurity, instant cold drink, strong wine, delay in the longitudinal desire, taking stomach as five viscera sea, spleen qi to operate, stomach distention, spleen stagnation, spleen qi obstruction, yu Fa, vomiting. "food stagnation blocks qi movement, so spleen strengthening and qi supplementing are needed on the basis of promoting digestion and removing stagnation; and in the "Lin Zhi Yu Yi Su-Jie Xuexiong": the grains of are not changed, and the damp and wind are also present; the loose stool, dirty and dirty, damp and hot; clear and white, wet and cold in loose stool; the soft body is soft and weak, and the damp is self-sinking; the retention of qi is not prohibited for a long time, and the damp-retention will be lost. ", food stagnation is easy to generate stagnated heat, and it is necessary to dispel stasis and clear heat, nourish yin and benefit stomach. The theory of the "spleen disease … … deficiency with abdominal fullness and borborygmus" in the theory of the Su Wen and zang-organ qi method, the theory of the Su Wen and the Mai Wen essence "also includes the following points: the stomach pulse is distended and the stomach pulse is deficient. On the other hand, deficiency of spleen and stomach, malnutrition of food, food stagnation, diarrhea and other diarrhea can be caused, and the effects of strengthening spleen and tonifying qi can be achieved on the basis of the previous therapeutic principle. The normal function of the stomach and intestine depends on the normal movement of the qi movement, and qi stagnation can cause slow down or even stagnation of the gastrointestinal peristalsis to lead to constipation, and the pathogenesis is qi stagnation, so the treatment method of regulating qi and stomach is used as a guiding drug. The invention relates to a hawthorn fruit, radish seed and phyllanthus emblica which are used as monarch drugs for promoting digestion, removing food stagnation, promoting blood circulation, removing blood stasis, relieving stuffiness, dredging viscera, promoting digestion and invigorating stomach; the artificially planted ginseng, the Chinese yam and the rhizoma polygonati invigorate spleen and replenish qi, warm middle-jiao and invigorate yang, invigorate qi and promote circulation, and the malt and the chicken's gizzard-membrane promote circulation of qi and promote digestion, invigorate spleen and promote appetite, and are jointly ministerial drugs; fructus Lycii, fructus Hippophae, as adjuvant drug, has effects in nourishing yin and invigorating stomach; pericarpium Citri Reticulatae and Poria regulate qi and harmonize stomach, and the whole formula can promote digestion and remove food stagnation, nourish yin and benefit stomach, and remove food stagnation together.
Detailed Description
The invention is further described below in conjunction with the detailed description. It is to be understood that these examples are illustrative of the present invention and are not intended to limit the scope of the present invention. Further, it is understood that various changes and modifications of the present invention may be made by those skilled in the art after reading the description of the present invention, and that such equivalents are intended to fall within the scope of the claims appended hereto.
Example 1: 25g of hawthorn, 20g of radish seed, 20g of phyllanthus emblica, 15g of artificially planted ginseng, 30g of Chinese yam, 20g of rhizoma polygonati, 20g of malt, 10g of chicken's gizzard-membrane, 25g of medlar, 20g of sea buckthorn, 20g of dried orange peel and 15g of poria cocos.
Drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into coarse powder, adding 8-12 times of water, decocting for 2 times and 1-2 hr each time, mixing extractive solutions, filtering, concentrating under reduced pressure to obtain soft extract with relative density of 1.20-1.28 at 60deg.C, spray drying, and making into granule.
Example 2: 20g of hawthorn, 25g of radish seed, 18g of phyllanthus emblica, 18g of artificially planted ginseng, 25g of Chinese yam, 22g of rhizoma polygonati, 15g of malt, 12g of chicken's gizzard-membrane, 20g of medlar, 25g of sea buckthorn, 18g of dried orange peel and 20g of poria cocos.
Drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae and Poria at 60-80deg.C, pulverizing into coarse powder with 15-30 mesh sieve, and making into teabag.
Example 3: 30g of hawthorn, 15g of radish seed, 22g of phyllanthus emblica, 12g of artificially planted ginseng, 35g of Chinese yam, 18g of rhizoma polygonati, 25g of malt, 8g of chicken's gizzard-membrane, 30g of medlar, 15g of sea buckthorn, 22g of dried orange peel and 10g of poria cocos.
Drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into coarse powder, adding 8-12 times of water, decocting for 1-2 hr each time, mixing extractive solutions, filtering, concentrating under reduced pressure to obtain soft extract with relative density of 1.20-1.28 at 60deg.C, spray drying, and making into tablet.
Example 4: 25g of hawthorn, 20g of radish seed, 20g of phyllanthus emblica, 15g of artificially planted ginseng, 30g of Chinese yam, 20g of rhizoma polygonati, 20g of malt, 10g of chicken's gizzard-membrane, 25g of medlar, 20g of sea buckthorn, 20g of dried orange peel and 15g of poria cocos.
Drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into fine powder of 80-120 mesh, adding water, making into pill, making into 4-5mm pill, and drying.
Example 5: effects on gastrointestinal motility in food stagnation model rats
1. And (3) molding: SPF-grade healthy SD rats, 40, male and female, weight (160+ -15) g, are provided by experimental animal centers of Jiangxi Chinese medical university, are divided into four groups, wherein one group is a normal group, the other three groups are a model group, the invention group and a positive medicine group respectively, on the basis of conventional feed, high-protein and high-calorie feed (the mixture of dried fish floss, bean powder, flour and milk powder is uniformly mixed according to the ratio of 1:2:1:1) is taken, and the model is continuously manufactured for 15 days, and the appetite of the rats is reduced, the actions are slow, the eyes are squinted, the spirit is low, the stomach is fluctuant after the model is manufactured, so that the model is proved to be successful.
2. Administration: after the molding is successful, each group is fed with conventional feed, and the normal group and the model group are filled with a proper amount of physiological saline, and the group takes 7.5g of the raw medicinal materials per kg/d of the granule prepared in the embodiment 1; the positive medicine group takes Baohe pill (national medicine standard Z34020521, shanghai Baobao Anqing pharmaceutical Co., ltd.) 7.5g raw medicine/kg/d, and is taken 1 time a day and continuously drenched for 30d.
3. Measurement of small intestine thrust rate: and after the experiment is finished, the rat is killed immediately after cervical dislocation, the system film is rapidly separated, the small intestine is taken out and is directly paved on white paper, and the distance from the pylorus to the full length of the ileocecum part and the pylorus to the front edge of the semi-solid paste of the carbon powder is measured. The small intestine thrust rate was calculated as the percentage of the distance from the pylorus to the leading edge of the semi-solid paste at the carbon end to the full length of the ileocecum:
small intestine propulsion (%) = (carbon powder semisolid paste was propelled in small intestine distance/rat small intestine full length) ×100%.
4. Effect on rat small intestine thrust: the results are shown in Table 1.
TABLE 1 influence on the intestinal motility of rats in the food retention model (%)
Group of | Small intestine propulsive rate (%) |
Normal group | 73.67±8.59 |
Model group | 55.90±6.71# |
Positive medicine group | 81.43±5.04** |
The invention group | 87.83±9.13** |
Note that: compared with the normal control group, the #P is less than 0.05; p <0.05, P < 0.01 compared to model control.
Compared with the normal control group, the small intestine propulsion rate of the rats in the model control group is relatively low, and the difference has statistical significance (P is less than 0.05), which indicates that the modeling is successful. After 30d administration, compared with a model control group, the small intestine propulsion rates of the positive control group and the rats in the group are improved, the differences have statistical significance (P is less than 0.01), and the effect of the group in the group is better than that of the group in the positive medicine.
Example 6: clinical trials
1. The experimental object: 100 outpatients all accord with the diagnosis standard of the infant food stagnation. After informed consent, the treatment group and the control group were randomized into 50 cases. In the control group, 27 men and 23 women are aged 6 months-5 years, and the course of disease is 2-12 months. The treatment group comprises 28 men and 22 women, the ages of 6 months-5 years, and the disease course of 2-12 months. The gender, age and course of disease of the two groups of patients were statistically analyzed, and the differences were not statistically significant (P > 0.05).
50 cases of children patients in the control group of the study are orally taken to ensure that the children patients are protected by pills (national medicine standard Z34020521, shanghai Baobao Longan Qingqing pharmaceutical Co., ltd.) and orally taken for 10 pills each time for 3 times/d. One treatment course is 2 weeks, and 2 treatment courses are taken. 50 infants in the treatment group are given the granule of example 1 12 g/time, 3 times/d, and the dosage of the infants with the age of less than 2 years old is halved. One treatment course is 2 weeks, and 2 treatment courses are taken. And (5) comparing and evaluating the two groups of clinical treatment effects after the treatment is finished.
2. Diagnostic criteria: the traditional Chinese medicine accords with the syndrome differentiation and typing standard of accumulation and stagnation proposed in the traditional Chinese medicine syndrome diagnosis curative effect standard, namely the clinical symptoms of accumulation and stagnation of diet include poor appetite, inappetence, abdominal distending pain, refusal of pressing, eructation, acid regurgitation, anorexia, vomiting, pain, diarrhea, pain relief after diarrhea, or constipation, loose stool, thick and greasy tongue fur and slippery pulse.
3. Curative effect judgment criteria: according to the traditional Chinese medicine disease diagnosis curative effect standard, the clinical curative effect is divided into: the effect is shown: after treatment, the clinical symptoms of the children patients are resolved, the appetite and the appetite are improved by 75 percent compared with the original level, and the integral of clinical symptoms is reduced by 70 percent or more. The method is effective: after treatment, clinical symptoms of the children are relieved, the appetite is improved by 50% compared with the original level, and the integral of clinical symptoms is reduced by 30% -70%. Invalidation: after treatment, the clinical symptoms of the children are unchanged, the appetite is not improved, and the integral of clinical symptoms is reduced by less than 30 percent. Total efficacy = (total number of cases-number of ineffective cases)/total case×100%
4. The treatment results are shown in Table 2.
Table 2 comparison of clinical efficacy
Group of | Has obvious effect | Effective and effective | Invalidation of | The total effective rate is% |
Treatment group | 24 | 23 | 3 | 94 |
Control group | 17 | 24 | 9 | 82 |
Table 2 shows the comparison of the two therapeutic effects, the total effective rate of the treatment group is 94%, and the total effective rate of the control group is 82%. The two groups of treatment effects are obviously different compared (P < 0.05), which shows that the treatment effect of the treatment group is better than that of the control group.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. The food with the effects of promoting digestion and removing food stagnation is characterized by being prepared from the following raw materials in parts by weight: 20-30 parts of hawthorn, 15-25 parts of radish seed, 18-22 parts of emblic leafflower fruit, 12-18 parts of artificially planted ginseng, 25-35 parts of Chinese yam, 18-22 parts of rhizoma polygonati, 15-25 parts of malt, 8-12 parts of chicken's gizzard-membrane, 20-30 parts of medlar, 15-25 parts of sea buckthorn, 18-22 parts of dried orange peel and 10-20 parts of poria cocos.
2. The food with the effect of promoting digestion and removing food stagnation according to claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 20-25 parts of hawthorn, 20-25 parts of radish seed, 18-20 parts of emblic leafflower fruit, 15-18 parts of artificially planted ginseng, 25-30 parts of Chinese yam, 20-22 parts of rhizoma polygonati, 15-20 parts of malt, 10-12 parts of chicken's gizzard-membrane, 20-25 parts of medlar, 20-25 parts of sea buckthorn, 18-20 parts of dried orange peel and 15-20 parts of poria cocos.
3. The food with the effect of promoting digestion and removing food stagnation according to claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 25 parts of hawthorn, 20 parts of radish seed, 20 parts of phyllanthus emblica, 15 parts of artificially planted ginseng, 30 parts of Chinese yam, 20 parts of rhizoma polygonati, 20 parts of malt, 10 parts of chicken's gizzard-membrane, 25 parts of medlar, 20 parts of sea buckthorn, 20 parts of dried orange peel and 15 parts of poria cocos.
4. The food with the effect of promoting digestion and removing food stagnation according to claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 20 parts of hawthorn, 25 parts of radish seed, 18 parts of emblic leafflower fruit, 18 parts of artificially planted ginseng, 25 parts of Chinese yam, 22 parts of rhizoma polygonati, 15 parts of malt, 12 parts of chicken's gizzard-skin, 20 parts of medlar, 25 parts of sea buckthorn, 18 parts of dried orange peel and 20 parts of poria cocos.
5. The food with the effect of promoting digestion and removing food stagnation according to claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 30 parts of hawthorn, 15 parts of radish seed, 22 parts of emblic leafflower fruit, 12 parts of artificially planted ginseng, 35 parts of Chinese yam, 18 parts of rhizoma polygonati, 25 parts of malt, 8 parts of chicken's gizzard-membrane, 30 parts of medlar, 15 parts of sea buckthorn, 22 parts of dried orange peel and 10 parts of poria cocos.
6. The food having the effect of promoting digestion and removing food stagnation according to claim 1, characterized in that the preparation method comprises the steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into coarse powder, adding 8-12 times of water, decocting for 2 times and 1-2 hr each time, mixing extractive solutions, filtering, concentrating under reduced pressure to obtain soft extract with relative density of 1.20-1.28 at 60deg.C, spray drying, and making into granule.
7. The food having the effect of promoting digestion and removing food stagnation according to claim 1, characterized in that the preparation method comprises the steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae and Poria at 60-80deg.C, pulverizing into coarse powder with 15-30 mesh sieve, and making into teabag.
8. The food having the effect of promoting digestion and removing food stagnation according to claim 1, characterized in that the preparation method comprises the steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into coarse powder, adding 8-12 times of water, decocting for 1-2 hr each time, mixing extractive solutions, filtering, concentrating under reduced pressure to obtain soft extract with relative density of 1.20-1.28 at 60deg.C, spray drying, and making into tablet.
9. The food having the effect of promoting digestion and removing food stagnation according to claim 1, characterized in that the preparation method comprises the steps of: drying fructus crataegi, raphani semen, fructus Phyllanthi, artificially planted Ginseng radix, rhizoma Dioscoreae, rhizoma Polygonati, fructus Hordei Germinatus, endothelium corneum Gigeriae Galli, fructus Lycii, fructus Hippophae, pericarpium Citri Tangerinae, and Poria, pulverizing into fine powder of 80-120 mesh, adding water, making into pill, making into 4-5mm pill, and drying.
10. Use of a food product with digestion promoting and food stagnation removing effects according to claim 1 for preparing a food product for eliminating food stagnation.
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