CN106039187A - Child Shi-kang tea and preparation method thereof - Google Patents

Child Shi-kang tea and preparation method thereof Download PDF

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CN106039187A
CN106039187A CN201610403239.2A CN201610403239A CN106039187A CN 106039187 A CN106039187 A CN 106039187A CN 201610403239 A CN201610403239 A CN 201610403239A CN 106039187 A CN106039187 A CN 106039187A
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parts
children
semen
spleen
health tea
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莫善列
欧莹
莫佳
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

Child Shi-kang tea is prepared from traditional Chinese medicinal materials in parts by weight as follows: 3-9 parts of ginseng, 3-8 parts of chicken's gizzard-membranes, 1-5 parts of kudzuvine roots, 1-5 parts of villous amomum fruits, 1-5 parts of radish seeds, 3-8 parts of gordon euryale seeds, 3-8 parts of white hyacinth beans, 3-8 parts of coix seeds, 3-8 parts of poria cocos, 1-3 parts of liquorice roots, 1-5 parts of malt, 2-6 parts of hawthorn fruits, 1-4 parts of Chinese yams, 1-4 parts of tangerine peel and 3-8 parts of lotus seeds. The child Shi-kang tea is fine in matching, adopts a reasonable formula, integrates the functions of heat clearing, toxin removal, spleen and stomach strengthening, qi regulation and digestion promotion, mainly aims to strengthen the spleen and the stomach and also has the functions of regulating viscera and regulating both qi and yin; on one hand, the tea can nourish yin and strengthen the body resistance, so that water in five elements is generated, wood in five elements is vigorous, pathogenic factors cannot linger, and on the other hand, the tea can cure diarrhoea and dispel pathogenic factors, an opposite and complementary effect is realized, vital qi is regained, the pathogenic factors are removed, and the tea has a relative good treatment effect on weakness of the spleen and the stomach of children, dyspepsia, poor appetite, abnormal defecation, sleepiness and fatigue, restless sleep, night terror, night cry and other symptoms.

Description

A kind of children's ten health tea and preparation method thereof
Background technology
The spleen and stomach in children is weak, how because of excess in feeding, the most ill, or tells greatly, caused by chronic diarrhea, impairing the spleen and stomach.Also have congenital Kidney qi is weak and causes the weakness of the spleen and stomach person day after tomorrow.Deficiency of spleen-QI, deficiency of spleen-YANG, insufficiency of stomach-QI, stomach yang deficiency can be divided into.Clinical common taste disease Suffer from, as stagnant, infantile consumption, vomit, diarrhoea etc., symptom is loss of appetite, and agitation is cry and screamed, and abdominal distention, defecates dry or dilute, and body of the tongue is inclined Red, tongue thickness in vain or thick greasy, geographic tongue, dormancy was felt unwell, was easily perspired night."Nei Jing" proposes the physiological function of taste, pathological change rule Rule.Li Dong Yuan propose " disorder of the spleen and stomach caused by internal damage, all kinds of diseases and ailments are by giving birth to " opinion, TCM holistic nursing care thought through nursing process all the time, Learn wildly from other's strong points, the data using the traditional Chinese medical science four diagnostic methods to collect analyzed, comprehensively, judgement etc. determine corresponding Nursing principles and method.
The spleen and stomach in children is weak, and transporting function is not enough, all diet are received, are digested, malabsorption and all damp-edema full or lift and lose Often, vomiting have loose bowels, or collapse of QI, have under one's command and have no right all cards of caused insufficiency of vital energy and blood, its reason all blame in taste.Children's period In the majority with deficiency syndrome, it is main that the traditional Chinese medical science advocates precautions, and proposes the thought of " superior doctor treating the disease before its onset ".Therefore at ordinary times it should be noted that pediatric diet and tableware Health, corrects monophagia and the bad habit of eating and drinking without temperance;Add in time and subtract clothes, reasonable arrangement diet;Advocate breast feeding, it is provided that Physical growth of children grows necessary nutrition;Strengthen outdoor activities, get sun, it is to avoid abdominal part is suffered from cold more.
" all infantile malnutritions all the spleen-stomach disease ", from the beginning of only incoordination between the spleen and stomach, transporting is not good for, the infantile malnutrition gas of meaning.Board loses strong fortune further, in stagnating Stop, the infantile malnutrition of meaning.Late period, then taste were deficient, and body fluid dries up, and gas is cloudy all empty, the chronic infantile malnutrition of meaning.Taste are saying of QI and blood biochemistry, taste Unstrong then QI and blood must be empty, the most then the five internal organs all damage, and accompanied symptoms happens frequently.Such as the splenopathy and liver, then deficiecny of liver-YIN, raw in liver-heat, mesh loses and nourishes; The splenopathy and the heart, then blood failing to tonify the heart, flaming of heart-fire in the interior, irritability.It is with the puckery photophobia of mesh, white membrane in eye, dysphoria and insomnia, aphtha of the mouth and tongue Can in succession occur etc. symptom.
When there is this state of an illness, eat febrifuge and JIANWEI XIAOSHI PIAN, compound recipe pancreatin dissipates or by Xiao ' erqixingcha effect not It is fairly obvious.Chinese medicine is of extensive knowledge and profound scholarship, have many good medicine benefit sides but or not unofficial biography, or underground, therefore so far there are no, and effect is bright Aobvious preventing and treating the spleen and stomach in children is weak, dyspepsia, inappetence, stool abnormity, and spirit is sleepy, sleep disorder, fright at night, night cry etc. The Chinese medicine report of disease.
Summary of the invention
It is an object of the invention to provide one can air making-up and spleen enlivening, appetite-stimulating indigestion-relieving, eliminating dampness by diuresis, the children's ten health tea of antidiarrheal, Weak for preventing and treating the spleen and stomach in children, dyspepsia, inappetence, stool abnormity, spirit is sleepy, sleep disorder, fright at night, night cry etc. Disease, all has preferable therapeutic effect.
The present invention realizes by the following technical solutions:
A kind of children's ten health tea, the composition of described children's ten health tea includes the medical material of following parts by weight: Radix Ginseng 3-9, Endothelium Corneum Gigeriae Galli 3-8, Radix Puerariae 1-5, Fructus Amomi 1-5, Semen Raphani 1-5, Semen Euryales 3-8, Semen Lablab Album 3-8, Semen Coicis 3-8, Poria 3-8, Radix Glycyrrhizae 1-3, wheat Bud 1-5, Fructus Crataegi 2-6, Rhizoma Dioscoreae 1-4, Pericarpium Citri Reticulatae 1-4, Semen Nelumbinis 3-8.
Described children's ten health tea, its preparation method comprises the following steps:
Step one: weigh Radix Ginseng, Endothelium Corneum Gigeriae Galli, Radix Puerariae, Fructus Amomi, Semen Raphani, Semen Euryales, Semen Lablab Album, Semen Coicis, Fu by weight Siberian cocklebur, Radix Glycyrrhizae, Fructus Hordei Germinatus, Fructus Crataegi, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae and Semen Nelumbinis, pulverize respectively, crosses 60 mesh sieves, and mixing, with mixing of obtaining relative to this step The alcohol reflux of the determining alcohol 65%~75% of compound quality 4~8 times 3 times, each 2 hours, united extraction liquid, mistake Filter;Regulation filtrate acid-base value uses hydrochloric acid or NaOH solution to pH6~6.5, the mode of regulation filtrate acid-base value;Stand, filter, Decompression filtrate recycling ethanol, to without alcohol taste, stands, centrifugation, the supernatant after centrifugation, and heating is concentrated into 50 DEG C~60 Relative density at DEG C is the mastic of 1.25~1.30;
Step 2: mastic step one obtained first is dried, is then placed within super micron mill pulverizing, then passed through Sieve, it is thus achieved that 300 mesh~the micropowders of 400 mesh;
Step 3: step 2 gained micropowders is added by weight appropriate amount of auxiliary materials mixing, is prepared as respectively by conventional formulation method Plant dosage form.
It is weak that described children's ten health tea is used for preventing or treat the spleen and stomach in children in preparation, dyspepsia, inappetence, greatly Just abnormal, spirit is sleepy, sleep disorder, fright at night, night cry medicine in purposes.
Described children's ten health tea can be prepared as oral liquid, granule, electuary, powder or solution.
Described adjuvant is selected from diluent, filler, sweeting agent, excipient, lubricant, binding agent, disintegrating agent and correctives In one or more.
Diluent is starch, dextrin, Icing Sugar, lactose, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, microcrystalline Cellulose, polyethylene One or more in ketopyrrolidine etc..
Filler is starch, dextrin, sucrose, microcrystalline Cellulose, lactose, modified starch, pregelatinized Starch, low-substituted hydroxypropyl Base cellulose, glucose, mannose, xylitol, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crosslinked polyethylene pyrroles One or more in alkanone, cross-linking sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose etc..
Sweeting agent is selected from one or both in white sugar, Mel and xylose.
Excipient is that one or more mixing in mannitol, Dextran-20, Dextran 40 and dextran 60 make With.
Lubricant be the one in magnesium stearate, Pulvis Talci, calcium stearate, stearic acid, hydrogenated vegetable oil, Polyethylene Glycol or Multiple.
Binding agent is starch, pregelatinized Starch, dextrin, maltodextrin, sucrose, arabic gum, gelatin, Methyl cellulose Element, carboxymethyl cellulose, ethyl cellulose, polyethylene adjoin pyrrolidone, xanthan gum, water, wax, alcohol, hydroxypropyl cellulose and hydroxypropyl One or more in ylmethyl cellulose.
Disintegrating agent is that Sodium Hydroxymethyl Stalcs, low-substituted hydroxypropyl cellulose, polyvinylpyrrolidone and crosslinking methylol are fine One or more in dimension element sodium.
Correctives is selected from aspartame, flavoring orange essence, Mint Essence etc..
When prepared dosage form is powder, the micropowders specially step 2 obtained, every 100g micropowders, Add 50g starch, be uniformly mixed, it is thus achieved that powder.
When prepared dosage form is oral liquid, it is specially mastic step one obtained, by every 100g mastic, adds honeybee Honey 50g, sucrose 20g, sodium benzoate 0.8g and water are appropriate, mixing, and hydro-oxidation sodium test solution adjusts pH value to 5~6, adds water To 1000ml, filter, embedding, sterilizing, obtain oral liquid.
When prepared dosage form is granule, take filler, disintegrating agent, sweeting agent are dispersed in the ultra micro of step 2 gained In fine powder, add binding agent and pelletize, be dried, obtain to add correctives by the granule of 16~24 mesh sieves, mix, obtain Granule.
In the raw material of Chinese medicine that the present invention chooses, each medicine active ingredient is analyzed:
Radix Ginseng (Classification system: Panax ginseng C. A. Mey) is herbaceos perennial, happiness cool place, blade pore-free And palisade tissue, it is impossible to retaining moisture, temperature can be burnt higher than 32 degree of blades, canopy density 0.7-0.8.Within usual 3 years, bloom, 5-6 Annual bearing, the month at florescence 5-6, really the phase 6-9 month.Be grown on the height above sea level between north latitude 33 degree 48 degree, hundreds of meters based on Pinus koraiensis Theropencedrymion or broad leaved and deciduous broad leaved sylvan life, originate in Northeast China, Korea, Korea S, Japan, Russia east.The another name of Radix Ginseng Being the king of Sphallerocarpus gracilis, Herba Stellariae Saxatilis, SHENCAO, BAICAO, be one of well-known " northeast three essentials-essence ", with fine jade treasure Ganoderma, Donga Colla Corii Asini is claimed For Chinese medicine national treasure.Nature and flavor: hardship sweet, micro-are flat.Gui Jing: return spleen, lung, heart channel.Function cures mainly: strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, spleen reinforcing Lung benefiting, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung breathes with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness Weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb;Heart failure, cardiogenic shock.
Endothelium Corneum Gigeriae Galli, Chinese medicine name.For Phasianidae animal man chickenGallusgallusdomesticus BrissonDry ballast Inwall.After killing chicken, take out chicken gizzard, peel inwall, cleaning, drying immediately.Nature and flavor: sweet are flat.Gui Jing: return spleen, stomach, small intestinal, bladder Warp.Function cures mainly: invigorating the stomach and promoting digestion, arresting seminal emission.Do not disappear for food stagnation, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
Radix Puerariae is legume pueraria lobata, Latin literary famePueraria lobata (Willd.) OhwiOr Radix Puerariae rattan, Latin Literary famePueraria thomsonii Benth.Dry root.Autumn, season in winter two excavate, and Herba Gelsemii Elegantis takes advantage of fresh-cut more and becomes sheet or fritter; It is dried;Radix Puerariae rattan is practised and claims " Pachyrhizua angulatus ", removes crust more, after smoking with sulfur, the most dry, and intercept or again rip cutting two halves are dried.Radix Puerariae Sweet in the mouth is pungent cool, returns spleen, stomach, lung meridian.There is expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, rash, yang invigorating antidiarrheal, dredge the meridian passage, alcoholic intoxication.With Have a headache in fever caused by exogenous pathogens, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels, dizziness and headache, apoplectic hemiplegia, the thoracic obstruction heart Bitterly, damage of the spleen and stomach caused by alcoholism.Additionally there is obvious hypotensive activity.
Fructus Amomi (Classification system:Amomum villosum Lour.) another name: Fructus Amomi, Changtai Fructus Amomi (Fujian), again Name Elettaria cardamomum (L.) Maton, perennial herb.Be band and subtropical zone zingiberaceous plant fruits and seeds, be the conventional armaticity simply of the traditional Chinese medical science Medical material.Plant height 1.5-3 rice, stem is scattered;Rhizome crawls ground, to save by brown film quality scale.Rhizome is sturdy, brownish red.Seed Group's point 3 lobes, every lobe seed 5~9 pieces, seed fragrant odour and high strong, as spice, the pepperyyest, its taste is like Camphor tree.It is dish in the Orient Flavoring agent, the particularly condiment of curry dish.Then it is usually used in pastries seasoning in Scandinavia, is also that the traditional Chinese medical science is conventional simply Armaticity medical material.Gather during fruit maturation between summer, autumn, dry or cold drying.Fructus Amomi is a kind of more gentle medical herbs.Main product In country in Southeast Asia.The traditional Chinese medical science is thought, mainly acts on the stomach of human body, kidney and spleen, it is possible to circulation of qi promoting seasoning, and stomach function regulating is amusing.Fructus Amomi is normal Coordinate with Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae etc., be suitable for treating the disease such as fullness in the epigastrium and chest, abdominal distention and little diet.
Semen Raphani (Classification system:Semen Raphani) it is the mature seed of crucifer Radix Raphani.Plant between summer, autumn Son extracts Herb time ripe, dries, and rubs seed, removes impurity, dries.Nature and flavor: pungent, sweet are flat.Gui Jing: return lung, spleen, stomach warp. Effect: help digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.Cure mainly: for retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.
Semen Euryales, Chinese medicine name.For nymphaeaceae plant Semen Euryales, Latin literary fameEuryale ferox Salisb.Drying and ripening Kernel.Spherical in class, it mostly is brokenly grain, complete person's diameter 5~8mm.There are brownish red endotesta, one end yellow-white in surface, accounts for complete Body 1/3, has the hilum trace of concave point shape, removes endotesta whitening color.Matter is harder, section white, mealiness.Odorless, lightly seasoned.It is distributed in From Heilungkiang to the ground such as Yunnan, Guangdong.Nature and flavor: sweet, puckery are flat.Gui Jing: return spleen, kidney channel.There is supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, remove Effect of wet leukorrhagia stopping.It is usually used in emission and spermatorrhea, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.
Semen Lablab Album, another name bean, Semen Vignae Cylindricae, south Seem Lablab Album;Latin literary fameDolicho, lablabL.Annual voluble herb The mature seed of plant Seem Lablab Album, annual voluble herb.Seem Lablab Album originates in the torrid areas such as India, Indonesia, about in Chinese Shanxi Between introduce China.Autumn, mature fruit of gathering in season in winter two, dry, and takes out seed, then dries.Seed flat ellipse or flat oval, Light Herba Amaranthi tricoloris is white or faint yellow on surface, smooth, slightly gloss, a lateral edges bossed white semilune strophiole.Feeble QI, lightly seasoned, That chews has beany flavor.Nature and flavor: sweet, tepor.Gui Jing: return spleen, stomach warp.Function cures mainly: invigorating the spleen for eliminating dampness, and in relieve summer heat.For taste Weakness, inappetence, diarrhea, leukorrhagia, heat-damp in summer vomiting and diarrhoea, abdominal distention uncomfortable in chest.
Semen Coicis is grass Semen Coicis, Latin literary fame:Coix lacryma-jobi L. var. ma-yuen (Roman.) StapfDry mature kernal.In width egg shape or oblong, long 4~8mm, wide 3~6mm.Surface milky, Smooth, occasionally there is the yellowish-brown seed coat of remaining.The blunt circle in one end, another end is wider and nick, has 1 light brown point-like hilum.Back side boss, The outside of belly has 1 wider and deep longitudinal furrow.Matter is solid, section white, mealiness.Feeble QI, taste is micro-sweet.Tap during fruit maturation in autumn and plant Strain, dries, and lays fruit, then dries, and removes shell, yellowish-brown seed coat and impurity, collects kernel.Nature and flavor: sweet, light are cool.Return Warp: return spleen, stomach, lung meridian.Function cures mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, and row is dense in heat clearing away.For edema, tinea pedis, dysuria is wet Numbness contracture, diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis;Verruca plana.
Poria is On Polyporaceae Poria, Latin literary famePoria cocos (Schw.) WolfDry sclerotia. More than 7~JIUYUE is excavated, remove silt after digging out, bank up after " diaphoresis ", spread out and dry in the air to dry tack free, then " diaphoresis ", it is repeated several times After scattering and disappearing to existing wrinkle, the big portion of internal moisture, dry in the shade, be referred to as " Poria ";Or fresh Poria is pressed different parts cutting, dry in the shade, It is called " Cortex Sclerotii Poriae " and " Poria block ".Poria: spherical in class, oval, oblate or irregular agglomerate, size is not One.Crust is thin and coarse, and sepia, to pitchy, has obvious shrinkage texture.Body weight, matter is solid, section graininess, some tools Crack, outer layer light brown, inner white, minority pale red, Radix Pini massonianae is entertained in some centres.Odorless, lightly seasoned, that chews sticks to one's teeth.Poria Skin: for the Poria crust under cutting, shape size differs.Outside sepia is to pitchy, inner face white or light brown.Matter is more loose Soft, somewhat elastic.Poria block: for the Poria of cutting after peeling, in block lamellar, not of uniform size.White, pale red or light brown. Poria: brownish red or pale red part are cut into bulk or lamellar.Poria: cut the white portion after Poria.Nature and flavor: Sweet, light, flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention is dizzy Throbbing with fear, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Radix Glycyrrhizae is glycyrrhizic legume, Latin literary fame:Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or the dry root of Glycyrrhiza glabra L. Glycyrrhiza glabra L..Root is cylinder Shape, long 25~100cm, diameter 0.6~3.5cm.Crust degree of tightness differs.Surface red brown or taupe brown, have significant vertical wrinkle, Rill, hole skin and sparse radicula trace.Matter is solid, and section shows slightly fibroid, yellow-white, mealiness, and cambium ring is obvious, and ray is put Penetrating shape, have has crack.Rhizome is cylinder, and there is bud trace on surface, has marrow in the middle part of section.Feeble QI, taste is sweet and special.Spring, autumn two Season excavates, and removes fibrous root, dries.Nature and flavor: sweet are flat.Gui Jing: GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat clearing away Removing toxic substances, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, Extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Fructus Hordei Germinatus, Chinese medicine name.It is grown in northern areas, for grass Fructus Hordei Vulgaris, Latin literary fame moreHordeurn vulgare L.Mature fruit through germinate be dried Preparation process product.After being soaked in water by wheat grain, keep suitable epidemic disaster, When plumelet length to about 5mm, dry or cold drying.Nature and flavor: sweet are flat.Gui Jing: return spleen, stomach warp.Function cures mainly: circulation of qi promoting helps digestion, Spleen benefiting and stimulating the appetite, moves back breast relieving distension.Not disappearing for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.
Fructus Crataegi (Classification system:Crataegus pinnatifida Bunge), have another name called fruit, Fructus Pyri Pashiae, Rosaceae mountain in mountain Short, bristly hair or beard belongs to, deciduous tree, high up to 6 meters.For circular piece, shrinkage is uneven, diameter 1~2.5cm, and thick 0.2~0.4cm.Crust is red, Tool wrinkle, has greyish white fleck.Sarcocarp buff is to light brown.Middle part transverse section tool 5 light yellow pits, but core come off more and Hollow.Visible short and thin carpopodium or calyx vestiges on some sheets.Feeble QI delicate fragrance, sour in the mouth, micro-sweet.Nature and flavor: sour, sweet, tepor.Return Warp: return spleen, stomach, Liver Channel.
Function cures mainly: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, produce Rear stasis blocking, trusted subordinate's twinge, hernia pain;Hyperlipemia.Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving effect strengthens.For meat stagnation, dysentery is not Refreshing.
Rhizoma Dioscoreae is Dioscoreaceae plant Rhizoma Dioscoreae, Latin literary fameDioscorea opposita Thunb. Dry rhizome.Winter Season stem and leaf withered after excavate, cut root head, clean, remove crust and fibrous root, with sulfur smoked after, be dried;Also there is selection loose suitable Straight dry Rhizoma Dioscoreae, puts in clear water, is dipped into without the dry heart, vexed, after smoking with sulfur, trims two ends, is twisted into plank cylindric, shines Dry, polishing, practise and claim " light yam ".Nature and flavor: sweet are flat.Gui Jing: return spleen, lung, kidney channel.Function cures mainly: spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, The kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung breathes with cough, and emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) Spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Pericarpium Citri Reticulatae, for rutaceae orange, Latin literary fameCitrus reticulata Blanco And variety is dry Dry mature peel.Harvesting ripe fruit, strips peel, dries or cold drying.Nature and flavor: bitter, pungent, temperature.Gui Jing: return lung, spleen channel. Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Semen Nelumbinis, for nymphaeaceae plant lotus, Latin literary fameNelumbo nucifera Gaertn. Dry mature seed. Ovalize or class are spherical, and long 1.2~1.8cm, diameter 0.8~1.4cm.Surface light yellowish brown to rufous, have thin longitudinal grin and Wider vein.Center, one end is papillae, and dark-brown has breach more, and its periphery is the most sagging.Matter is hard, and seed coat is thin, is difficult to Peel off.Cotyledon 2, yellow-white, plump, in have space, the green Plumula Nelumbinis of tool.Odorless is sweet in the mouth, micro-puckery;Plumula Nelumbinis bitter in the mouth.Remove lotus The heart person claim Semen Nelumbinis.Tap Receptaculum Nelumbinis during fruit maturation in autumn, take out fruit, remove peel, be dried.Concoct: slightly soak, run through, cut, Remove the heart, be dried.Nature and flavor: sweet, puckery are flat.Gui Jing: return spleen, kidney, heart channel.Function cures mainly: tonifying spleen and stopping diarrhea, kidney tonifying arresting seminal emission, and nourish heart peace God.For insufficiency of the spleen chronic diarrhea, leukorrhagia of passing out semen, palpitation and insomnia.
Monarch
Chinese medicine preparation of the present invention captures the length of all sides, and combines Long-term clinical experience addition or subtraction of changes and form.Monarch drug is: Radix Ginseng, chicken Endothelium corneum, Semen Raphani.Radix Ginseng, records according to " detailed outline ": " controlling man's all deficiency syndrome of woman, generate heat spontaneous perspiration, dizziness and headache, and food is told in regurgitation, Malaria, sliding chronic dysentery of rushing down, frequent micturition, drench drip, overstrain internal injury, apoplexy, heatstroke, flaccidity syndrome and arthralgia syndrome, spit blood, hemoptysis, hematochezia, stranguria with blood, metrorrhagia, tire Front puerperal all diseases." Endothelium Corneum Gigeriae Galli, the taste of chicken are also.In have porcelain stone, copper, ferrum all can digest, its kind blood stasis dispelling is long-pending to be understood.Not only can disappear Taste are long-pending, and no matter internal organs where has long-pending, and Endothelium Corneum Gigeriae Galli all can disappear it, is with man's mass beside the umbilicus, woman's abdominal mass, takes it for a long time, all can Cure.The card of the most all asthenia, the many stasis of bloods of its meridians are stagnant, arrange in pairs or groups with Endothelium Corneum Gigeriae Galli and Radix Ginseng, change its disease unraveling silk network stagnant.Semen Raphani, no matter Or raw or fry, all can regulating QI to remove the stagnation, relieving distension is except full, and this is the product of activating QI, the product of non-dispelling the stagnated QI.Pleasant so as to helping digestion, turn and do not feel frustrated, Because it can enter diet more, contented its of edema caused by disorder of QI is supported also.If in order to except full gate strongly fragrant, and help it with ginseng, stilbene, all medicines of art, though many clothes clothes for a long time, Also what is to feeling frustrated point.Ministerial drug is: Fructus Crataegi, Pericarpium Citri Reticulatae, Fructus Hordei Germinatus.Fructus Crataegi has regulation effect to gastrointestinal motility function, to spasm shape The gastrointestinal smooth muscle of state has inhibitory action, and the smooth muscle of relaxed state is had excitation.Pericarpium Citri Reticulatae and the same use of Fructus Crataegi, for food stagnation The stagnation of QI, abdominal distention person.Fructus Hordei Germinatus spleen reinforcing insufficiency of stomach, wide the intestines and stomach.A few taste ministerial drugs and monarch drug compatibility can improve therapeutic effect.
The children's ten health tea compatibility of the present invention is superior, reasonable recipe, melting down thermal detoxification, invigorating the spleen and regulating the stomach, the effect that helps digestion of regulating the flow of vital energy It is a stove, with invigorating the spleen and regulating the stomach as important department, people having the same aspiration and interest internal organs, take into account gas cloudy, on the one hand YIN nourishing righting, make water generating wood prosperous and do not love heresy, On the one hand rushing down clearly eliminating evil, oppose each other and yet also complement each other, eutopic reduction heresy is removed, therefore weak for treatment the spleen and stomach in children, dyspepsia, inappetence, greatly Just abnormal, spirit is sleepy, sleep disorder, and the disease such as fright at night, night cry all has preferable therapeutic effect.
The prominent substantive distinguishing features of the present invention with significantly progress is:
1, the Chinese medicine preparation of the present invention presses theory of Chinese medical science by Radix Ginseng, Endothelium Corneum Gigeriae Galli, Radix Puerariae, Fructus Amomi, Semen Raphani, Semen Euryales, Semen Lablab Album, the heart of a lotus seed Semen Coicis, Poria, Radix Glycyrrhizae, Fructus Hordei Germinatus, Fructus Crataegi, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae and Semen Nelumbinis are prepared from by medicine technique, with reference to Chinese medicine pharmacology at all times Research Achievement, weak to the spleen and stomach in children based on Chinese medicine, dyspepsia, inappetence, stool abnormity, spirit is sleepy, and sleep is not Peace, pathogenetic understanding of the disease such as fright at night, night cry and Therapeutic Principle, it is possible to rapidly and effectively treat, compatibility is proper, treatment Effective, expense is low, has no side effect;
2, the children's ten health tea of the present invention has natural, safe and nontoxic, efficient, raising immunity of organisms compared to existing technology Advantage, can adjust the imbalance state of body, reaches effect for the treatment of both the principal and secondary aspects of a disease;
3, the children's ten health tea of the present invention, its determined curative effect, safe ready, it is not necessary to hospitalization;
4, the children's ten health tea compatibility of the present invention is superior, reasonable recipe, and melting down thermal detoxification, invigorating the spleen and regulating the stomach, the effect that helps digestion of regulating the flow of vital energy are One stove, with invigorating the spleen and regulating the stomach as important department, people having the same aspiration and interest internal organs, take into account gas cloudy, on the one hand YIN nourishing righting, make water generating wood prosperous and do not love heresy, one Aspect is rushed down clearly eliminating evil, opposes each other and yet also complement each other, and eutopic reduction heresy is removed, therefore weak for treatment the spleen and stomach in children, dyspepsia, inappetence, stool Abnormal, spirit is sleepy, sleep disorder, and the disease such as fright at night, night cry all has preferable therapeutic effect;
5, the children's ten health tea expense of the present invention is than less expensive, instant effect, and curative effect is short, and cure rate is high.
Detailed description of the invention
Embodiment 1
A kind of children's ten health tea, the composition of described children's ten health tea includes the medical material of following parts by weight: Radix Ginseng 3, Endothelium Corneum Gigeriae Galli 3, Radix Puerariae 1, Fructus Amomi 1, Semen Raphani 1, Semen Euryales 3, Semen Lablab Album 3, Semen Coicis 3, Poria 3, Radix Glycyrrhizae 1, Fructus Hordei Germinatus 1, Fructus Crataegi 2, Rhizoma Dioscoreae 1, Pericarpium Citri Reticulatae 1, Semen Nelumbinis 3.
Described children's ten health tea, its preparation method comprises the following steps:
Step one: weigh Radix Ginseng, Endothelium Corneum Gigeriae Galli, Radix Puerariae, Fructus Amomi, Semen Raphani, Semen Euryales, Semen Lablab Album, Semen Coicis, Fu by weight Siberian cocklebur, Radix Glycyrrhizae, Fructus Hordei Germinatus, Fructus Crataegi, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae and Semen Nelumbinis, pulverize respectively, crosses 60 mesh sieves, and mixing, with mixing of obtaining relative to this step The alcohol reflux of the determining alcohol 65%~75% of compound quality 4~8 times 3 times, each 2 hours, united extraction liquid, filters Regulation filtrate acid-base value uses hydrochloric acid or NaOH solution to pH6~6.5, the mode of regulation filtrate acid-base value;Stand, filter, filter Liquid decompression recycling ethanol, to without alcohol taste, stands, centrifugation, the supernatant after centrifugation, and heating is concentrated into 50 DEG C~60 DEG C Under the mastic that relative density is 1.25~1.30;
Step 2: mastic step one obtained first is dried, is then placed within super micron mill pulverizing, then passed through Sieve, it is thus achieved that 300 mesh~the micropowders of 400 mesh;
Step 3: step 2 gained micropowders is added by weight appropriate amount of auxiliary materials mixing, is prepared as respectively by conventional formulation method Plant dosage form.
It is weak that described children's ten health tea is used for preventing or treat the spleen and stomach in children in preparation, dyspepsia, inappetence, greatly Just abnormal, spirit is sleepy, sleep disorder, fright at night, night cry medicine in purposes.
Described children's ten health tea can be prepared as oral liquid, granule, electuary, powder or solution.
Described adjuvant is selected from diluent, filler, sweeting agent, excipient, lubricant, binding agent, disintegrating agent and correctives In one or more.
Diluent is starch, dextrin, Icing Sugar, lactose, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, microcrystalline Cellulose, polyethylene One or more in ketopyrrolidine etc..
Filler is starch, dextrin, sucrose, microcrystalline Cellulose, lactose, modified starch, pregelatinized Starch, low-substituted hydroxypropyl Base cellulose, glucose, mannose, xylitol, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crosslinked polyethylene pyrroles One or more in alkanone, cross-linking sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose etc..
Sweeting agent is selected from one or both in white sugar, Mel and xylose.
Excipient is that one or more mixing in mannitol, Dextran-20, Dextran 40 and dextran 60 make With.
Lubricant be the one in magnesium stearate, Pulvis Talci, calcium stearate, stearic acid, hydrogenated vegetable oil, Polyethylene Glycol or Multiple.
Binding agent is starch, pregelatinized Starch, dextrin, maltodextrin, sucrose, arabic gum, gelatin, Methyl cellulose Element, carboxymethyl cellulose, ethyl cellulose, polyethylene adjoin pyrrolidone, xanthan gum, water, wax, alcohol, hydroxypropyl cellulose and hydroxypropyl One or more in ylmethyl cellulose.
Disintegrating agent is that Sodium Hydroxymethyl Stalcs, low-substituted hydroxypropyl cellulose, polyvinylpyrrolidone and crosslinking methylol are fine One or more in dimension element sodium.
Correctives is selected from aspartame, flavoring orange essence, Mint Essence etc..
When prepared dosage form is powder, the micropowders specially step 2 obtained, every 100g micropowders, Add 50g starch, be uniformly mixed, it is thus achieved that powder.
When prepared dosage form is oral liquid, it is specially mastic step one obtained, by every 100g mastic, adds honeybee Honey 50g, sucrose 20g, sodium benzoate 0.8g and water are appropriate, mixing, and hydro-oxidation sodium test solution adjusts pH value to 5~6, adds water To 1000ml, filter, embedding, sterilizing, obtain oral liquid.
When prepared dosage form is granule, take filler, disintegrating agent, sweeting agent are dispersed in the ultra micro of step 2 gained In fine powder, add binding agent and pelletize, be dried, obtain to add correctives by the granule of 16~24 mesh sieves, mix, obtain Granule.
Embodiment 2
A kind of children's ten health tea, the composition of described children's ten health tea includes the medical material of following parts by weight: Radix Ginseng 6, Endothelium Corneum Gigeriae Galli 5.5, Radix Puerariae 3, Fructus Amomi 3, Semen Raphani 3, Semen Euryales 5.5, Semen Lablab Album 5.5, Semen Coicis 5.5, Poria 5.5, Radix Glycyrrhizae 2, Fructus Hordei Germinatus 3, Fructus Crataegi 4, Rhizoma Dioscoreae 2.5, Pericarpium Citri Reticulatae 2.5, Semen Nelumbinis 5.5.
Described children's ten health tea, its preparation method comprises the following steps:
Step one: weigh Radix Ginseng, Endothelium Corneum Gigeriae Galli, Radix Puerariae, Fructus Amomi, Semen Raphani, Semen Euryales, Semen Lablab Album, Semen Coicis, Fu by weight Siberian cocklebur, Radix Glycyrrhizae, Fructus Hordei Germinatus, Fructus Crataegi, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae and Semen Nelumbinis, pulverize respectively, crosses 60 mesh sieves, and mixing, with mixing of obtaining relative to this step The alcohol reflux of the determining alcohol 65%~75% of compound quality 4~8 times 3 times, each 2 hours, united extraction liquid, mistake Filter;Regulation filtrate acid-base value uses hydrochloric acid or NaOH solution to pH6~6.5, the mode of regulation filtrate acid-base value;Stand, filter, Decompression filtrate recycling ethanol, to without alcohol taste, stands, centrifugation, the supernatant after centrifugation, and heating is concentrated into 50 DEG C~60 Relative density at DEG C is the mastic of 1.25~1.30;
Step 2: mastic step one obtained first is dried, is then placed within super micron mill pulverizing, then passed through Sieve, it is thus achieved that 300 mesh~the micropowders of 400 mesh;
Step 3: step 2 gained micropowders is added by weight appropriate amount of auxiliary materials mixing, is prepared as respectively by conventional formulation method Plant dosage form.
It is weak that described children's ten health tea is used for preventing or treat the spleen and stomach in children in preparation, dyspepsia, inappetence, greatly Just abnormal, spirit is sleepy, sleep disorder, fright at night, night cry medicine in purposes.
Described children's ten health tea can be prepared as oral liquid, granule, electuary, powder or solution.
Described adjuvant is selected from diluent, filler, sweeting agent, excipient, lubricant, binding agent, disintegrating agent and correctives In one or more.
Diluent is starch, dextrin, Icing Sugar, lactose, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, microcrystalline Cellulose, polyethylene One or more in ketopyrrolidine etc..
Filler is starch, dextrin, sucrose, microcrystalline Cellulose, lactose, modified starch, pregelatinized Starch, low-substituted hydroxypropyl Base cellulose, glucose, mannose, xylitol, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crosslinked polyethylene pyrroles One or more in alkanone, cross-linking sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose etc..
Sweeting agent is selected from one or both in white sugar, Mel and xylose.
Excipient is that one or more mixing in mannitol, Dextran-20, Dextran 40 and dextran 60 make With.
Lubricant be the one in magnesium stearate, Pulvis Talci, calcium stearate, stearic acid, hydrogenated vegetable oil, Polyethylene Glycol or Multiple.
Binding agent is starch, pregelatinized Starch, dextrin, maltodextrin, sucrose, arabic gum, gelatin, Methyl cellulose Element, carboxymethyl cellulose, ethyl cellulose, polyethylene adjoin pyrrolidone, xanthan gum, water, wax, alcohol, hydroxypropyl cellulose and hydroxypropyl One or more in ylmethyl cellulose.
Disintegrating agent is that Sodium Hydroxymethyl Stalcs, low-substituted hydroxypropyl cellulose, polyvinylpyrrolidone and crosslinking methylol are fine One or more in dimension element sodium.
Correctives is selected from aspartame, flavoring orange essence, Mint Essence etc..
When prepared dosage form is powder, the micropowders specially step 2 obtained, every 100g micropowders, Add 50g starch, be uniformly mixed, it is thus achieved that powder.
When prepared dosage form is oral liquid, it is specially mastic step one obtained, by every 100g mastic, adds honeybee Honey 50g, sucrose 20g, sodium benzoate 0.8g and water are appropriate, mixing, and hydro-oxidation sodium test solution adjusts pH value to 5~6, adds water To 1000ml, filter, embedding, sterilizing, obtain oral liquid.
When prepared dosage form is granule, take filler, disintegrating agent, sweeting agent are dispersed in the ultra micro of step 2 gained In fine powder, add binding agent and pelletize, be dried, obtain to add correctives by the granule of 16~24 mesh sieves, mix, obtain Granule.
Embodiment 3
A kind of children's ten health tea, the composition of described children's ten health tea includes the medical material of following parts by weight: Radix Ginseng 9, Endothelium Corneum Gigeriae Galli 8, Radix Puerariae 5, Fructus Amomi 5, Semen Raphani 5, Semen Euryales 8, Semen Lablab Album 8, Semen Coicis 8, Poria 8, Radix Glycyrrhizae 3, Fructus Hordei Germinatus 5, Fructus Crataegi 6, Rhizoma Dioscoreae 4, Pericarpium Citri Reticulatae 4, Semen Nelumbinis 8.
Described children's ten health tea, its preparation method comprises the following steps:
Step one: weigh Radix Ginseng, Endothelium Corneum Gigeriae Galli, Radix Puerariae, Fructus Amomi, Semen Raphani, Semen Euryales, Semen Lablab Album, Semen Coicis, Fu by weight Siberian cocklebur, Radix Glycyrrhizae, Fructus Hordei Germinatus, Fructus Crataegi, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae and Semen Nelumbinis, pulverize respectively, crosses 60 mesh sieves, and mixing, with mixing of obtaining relative to this step The alcohol reflux of the determining alcohol 65%~75% of compound quality 4~8 times 3 times, each 2 hours, united extraction liquid, mistake Filter;Regulation filtrate acid-base value uses hydrochloric acid or NaOH solution to pH6~6.5, the mode of regulation filtrate acid-base value;Stand, filter, Decompression filtrate recycling ethanol, to without alcohol taste, stands, centrifugation, the supernatant after centrifugation, and heating is concentrated into 50 DEG C~60 Relative density at DEG C is the mastic of 1.25~1.30;
Step 2: mastic step one obtained first is dried, is then placed within super micron mill pulverizing, then passed through Sieve, it is thus achieved that 300 mesh~the micropowders of 400 mesh;
Step 3: step 2 gained micropowders is added by weight appropriate amount of auxiliary materials mixing, is prepared as respectively by conventional formulation method Plant dosage form.
It is weak that described children's ten health tea is used for preventing or treat the spleen and stomach in children in preparation, dyspepsia, inappetence, greatly Just abnormal, spirit is sleepy, sleep disorder, fright at night, night cry medicine in purposes.
Described children's ten health tea can be prepared as oral liquid, granule, electuary, powder or solution.
Described adjuvant is selected from diluent, filler, sweeting agent, excipient, lubricant, binding agent, disintegrating agent and correctives In one or more.
Diluent is starch, dextrin, Icing Sugar, lactose, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, microcrystalline Cellulose, polyethylene One or more in ketopyrrolidine etc..
Filler is starch, dextrin, sucrose, microcrystalline Cellulose, lactose, modified starch, pregelatinized Starch, low-substituted hydroxypropyl Base cellulose, glucose, mannose, xylitol, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crosslinked polyethylene pyrroles One or more in alkanone, cross-linking sodium carboxymethyl cellulose, low-substituted hydroxypropyl cellulose etc..
Sweeting agent is selected from one or both in white sugar, Mel and xylose.
Excipient is that one or more mixing in mannitol, Dextran-20, Dextran 40 and dextran 60 make With.
Lubricant be the one in magnesium stearate, Pulvis Talci, calcium stearate, stearic acid, hydrogenated vegetable oil, Polyethylene Glycol or Multiple.
Binding agent is starch, pregelatinized Starch, dextrin, maltodextrin, sucrose, arabic gum, gelatin, Methyl cellulose Element, carboxymethyl cellulose, ethyl cellulose, polyethylene adjoin pyrrolidone, xanthan gum, water, wax, alcohol, hydroxypropyl cellulose and hydroxypropyl One or more in ylmethyl cellulose.
Disintegrating agent is that Sodium Hydroxymethyl Stalcs, low-substituted hydroxypropyl cellulose, polyvinylpyrrolidone and crosslinking methylol are fine One or more in dimension element sodium.
Correctives is selected from aspartame, flavoring orange essence, Mint Essence etc..
When prepared dosage form is powder, the micropowders specially step 2 obtained, every 100g micropowders, Add 50g starch, be uniformly mixed, it is thus achieved that powder.
When prepared dosage form is oral liquid, it is specially mastic step one obtained, by every 100g mastic, adds honeybee Honey 50g, sucrose 20g, sodium benzoate 0.8g and water are appropriate, mixing, and hydro-oxidation sodium test solution adjusts pH value to 5~6, adds water To 1000ml, filter, embedding, sterilizing, obtain oral liquid.
When prepared dosage form is granule, take filler, disintegrating agent, sweeting agent are dispersed in the ultra micro of step 2 gained In fine powder, add binding agent and pelletize, be dried, obtain to add correctives by the granule of 16~24 mesh sieves, mix, obtain Granule.
The present invention treats the application effect of the Chinese medicine preparation of urinary system calculus
Children's ten health tea of the present invention is studied at the beginning of 2013 and manufactures experimently out, and treats to part children's, and experimenter has 203 Name, wherein has weakness of the spleen and stomach, dyspepsia, inappetence, stool abnormity, and spirit is sleepy, sleep disorder, the disease such as fright at night, night cry. The children's ten health tea using the present invention is treated, and every day 2-3 time, 7 days courses for the treatment of, result patient takes rear effective percentage and reaches Within more than 98%, 2-3 days, symptom considerably reduces, and within 5-7 days, is almost recovered, except 5 symptom more severe cases need hospital treatment with Outward, 198 the most do not spend hospital, the most do not take Western medicine.
Case study on implementation:
Case one: Huang, 5 years old, because spleen and stomach function is bad, as long as occurring that anorexia, situation particular about food have half a year.And due to length Phase has no appetite, and nutrition does not catches up with, the growth of each side such as the brain of Huang, also poor than age cohorts.Whole people also seems Emaciation and sallow complexion, lethargy.Little Huang anorexia, particular about food, all lack of proper care because of taste, start upon somebody's introduction to take children's ten health tea of the present invention Carry out attempting treatment, every day 3 doses.After taking medicine 3 days slowly overeat a bit, after taking 1 course for the treatment of, Huang has a good complexion, appetite The biggest.
Case two: leaf, female, 8 months, because of do not think after fever caused by exogenous pathogens breast food, time and vomit, within two days, only fed two bottles of Fructus Citri tangerinaes Water, drips breast and does not enters, take Western medicine invalid.Start to take children's ten health tea of the present invention upon somebody's introduction to carry out attempting treatment, every day 2 doses. Symptom on the same day of taking medicine takes a turn for the better, and can simply take food, fully recover after taking 3 days after taking 2 days.
Case three: beam, female, 4 years old.Infant, because of gluttonous snacks, engendered loss of appetite before half a year, poor appetite, slightly Many feeds, just have loose bowels next day, just in carry food debris secretly, health is day by day become thin, angel, easily perspire.Repeatedly treat through doctor trained in Western medicine, not Being clearly better, thin white fur of tongue, arteries and veins is soft weak.Dialectical for weakness of the spleen and stomach, transporting is lost strong.Start to take the present invention upon somebody's introduction little Youngster ten health tea carries out attempting treatment, every day 3 doses.After 2 days, spirit takes a turn for the better, and diet can enter Vegetable.Spirit day after taking 5 days Good, to have rosy cheeks, diet is normal, can enter the most greasy product.After one course for the treatment of, seeing that infant is energetic, diet is just Often, two just self-regulated.
Case four: Hu, man, in July, to have a fever recently, flow thin nasal discharge, aquiform stool of having loose bowels medication in 3 days is invalid.Survey body temperature 38 DEG C, Since the head of a family tells idiopathy, appetite spirit is poor, accompanies uneasiness of crying and screaming.Start to take children's ten health tea of the present invention upon somebody's introduction to taste Examination treatment, every day 2 doses.Symptom on the same day of taking medicine takes a turn for the better, and takes transference cure after 2 days, fully recovers after taking 3 days.
Case five: Huang, man, 8 months, the sleep disorder bimester of near, cry and scream, irritability, startle, hyperhidrosis, defecation Normally, appetite is normal.Sick latter 5 months beginning recurrent diarrhea 3 times, each 57 days, without jaundice medical history and special history of taking medicine.Through people Introduction starts to take children's ten health tea of the present invention and carries out attempting treatment, every day 2 doses.After taking medicine 2 days, symptom takes a turn for the better, after taking 5 days Transference cure, fully recovers after taking a course for the treatment of, sees that infant is energetic, and diet is normal, two just self-regulateds.
Case six: beam, female, in June, more than May of becoming thin, refusing to eat is admitted to hospital for 2 days.Infant birth plays body weight not the later moon Increase, and gradually become thin.Closely February, spirit was poor, and appetite substantially goes down.Nearly 2 days appetite differences, enter vomiting right after eating, and sob is low;Spirit extreme difference. Do not generate heat, do not cough, without diarrhoea.Start to take children's ten health tea of the present invention upon somebody's introduction to carry out attempting treatment, every day 2 Agent.After taking medicine 2 days, symptom takes a turn for the better, and takes transference cure after 5 days, fully recovers, see that infant is energetic, diet after taking a course for the treatment of Normally, two just self-regulated.
Seldom there is simple deficiency syndrome or simple excess syndrome in children's's gastrointestinal dysfunction, dyspepsia, and most of infant taste are empty Weak, once eating and drinking without temperance, nurse improper easily cause " stagnating " phenomenon, the deficiency in origin domination of pathogen, simulataneous insufficiency and excessive disease occur.Children's of the present invention Ten health tea have spleen benefiting and stimulating the appetite, effect of removing food stagnancy reason intestinal, cure mainly weakness of the spleen and stomach, dyspepsia, inappetence, stool abnormity, essence God is sleepy, sleep disorder, the disease such as fright at night, night cry.Rhizoma Dioscoreae in children's ten health tea side of the present invention, can spleen invigorating qi-restoratives;Poria born fluid, Loosing the interspaces of skin and muscles;Semen Euryales sweet in the mouth spleen reinforcing, therefore energy dampness removing, and stomachache of having loose bowels can be controlled;It is aided with Fructus Hordei Germinatus, hawthorn digesting intestinal stasis relieving;Pericarpium Citri Reticulatae can spleen invigorating Astringing intestine to stop diarrhea, regulates the flow of vital energy in tune, recovers gastrointestinal function, and can enhancing human body immunity power.According to clinical verification, children's ten health tea of the present invention " is mended And the most stagnant, disappear and do not hinder ", treating both the principal and secondary aspects of a disease, treatment the spleen and stomach in children is weak, dyspepsia, inappetence, stool abnormity, spirit Sleepy, sleep disorder, the disease such as fright at night, night cry is evident in efficacy, and clinic is promoted.

Claims (8)

1. a children's ten health tea, it is characterised in that the composition of described children's ten health tea includes the Chinese medicines of following parts by weight Material: Radix Ginseng 3-9, Endothelium Corneum Gigeriae Galli 3-8, Radix Puerariae 1-5, Fructus Amomi 1-5, Semen Raphani 1-5, Semen Euryales 3-8, Semen Lablab Album 3-8, Semen Coicis 3-8, Fu Siberian cocklebur 3-8, Radix Glycyrrhizae 1-3, Fructus Hordei Germinatus 1-5, Fructus Crataegi 2-6, Rhizoma Dioscoreae 1-4, Pericarpium Citri Reticulatae 1-4, Semen Nelumbinis 3-8.
Children's ten health tea the most according to claim 1, it is characterised in that its preparation method comprises the following steps:
Step one: weigh Radix Ginseng, Endothelium Corneum Gigeriae Galli, Radix Puerariae, Fructus Amomi, Semen Raphani, Semen Euryales, Semen Lablab Album, Semen Coicis, Fu by weight Siberian cocklebur, Radix Glycyrrhizae, Fructus Hordei Germinatus, Fructus Crataegi, Rhizoma Dioscoreae, Pericarpium Citri Reticulatae and Semen Nelumbinis, pulverize respectively, crosses 60 mesh sieves, and mixing, with mixing of obtaining relative to this step The alcohol reflux of the determining alcohol 65%~75% of compound quality 4~8 times 3 times, each 2 hours, united extraction liquid, mistake Filter;Regulation filtrate acid-base value uses hydrochloric acid or NaOH solution to pH6~6.5, the mode of regulation filtrate acid-base value;Stand, filter, Decompression filtrate recycling ethanol, to without alcohol taste, stands, centrifugation, the supernatant after centrifugation, and heating is concentrated into 50 DEG C~60 Relative density at DEG C is the mastic of 1.25~1.30;
Step 2: mastic step one obtained first is dried, is then placed within super micron mill pulverizing, then passed through Sieve, it is thus achieved that 300 mesh~the micropowders of 400 mesh;
Step 3: step 2 gained micropowders is added by weight appropriate amount of auxiliary materials mixing, is prepared as respectively by conventional formulation method Plant dosage form.
It is weak that children's ten health tea the most according to claim 1 is used for preventing or treat the spleen and stomach in children in preparation, dyspepsia, Inappetence, stool abnormity, spirit sleepy, sleep disorder, fright at night, night cry medicine in purposes.
Children's ten health tea the most according to claim 1, it is characterised in that: described children's ten health tea can be prepared as being administered orally Liquid, granule, electuary, powder or solution.
5. according to the preparation method of children's described in claim 20 health tea, it is characterised in that described adjuvant selected from diluent, One or more in filler, sweeting agent, excipient, lubricant, binding agent, disintegrating agent and correctives.
The preparation method of children's ten health tea the most according to claim 2, it is characterised in that: when prepared dosage form is powder Time, it is specially micropowders step 2 obtained, every 100g micropowders, adds 50g starch, be uniformly mixed, obtain Obtain powder.
The preparation method of children's ten health tea the most according to claim 2, it is characterised in that: when prepared dosage form is oral During liquid, it is specially mastic step one obtained, by every 100g mastic, adds Mel 50g, sucrose 20g, sodium benzoate 0.8g And water is appropriate, mixing, hydro-oxidation sodium test solution is adjusted pH value to 5~6, is added water to 1000ml, filters, embedding, sterilizing, obtain mouth Take liquid.
The preparation method of children's ten health tea the most according to claim 2, it is characterised in that: when prepared dosage form is granule Time, take filler, disintegrating agent, sweeting agent are dispersed in the micropowders of step 2 gained, add binding agent and pelletize, be dried, To adding correctives, mixing by the granule of 16~24 mesh sieves, obtain granule.
CN201610403239.2A 2016-06-12 2016-06-12 Child Shi-kang tea and preparation method thereof Pending CN106039187A (en)

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CN106615465A (en) * 2016-12-28 2017-05-10 张四清 Digestion-promoting and stomach-strengthening tea
CN107890542A (en) * 2017-12-26 2018-04-10 湖南知达医药科技有限公司 Treat the Chinese medicine composition and its preparation method of diarrhoea
CN108379537A (en) * 2018-05-09 2018-08-10 丛念滋 A kind of infant's invigorating the spleen to arrest diarrhea herbaceous plant drink
CN108402238A (en) * 2018-03-20 2018-08-17 重庆旭焰实业有限公司 A kind of honey citron tea and its preparation method and application
CN108669533A (en) * 2018-03-30 2018-10-19 杭州多源科技有限公司 A kind of meal replacing food and preparation method thereof of conditioning shield stomach
CN112006137A (en) * 2020-09-17 2020-12-01 傅松涛 Spleen-tonifying and stomach-nourishing Su-radish tea and preparation method thereof

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106615465A (en) * 2016-12-28 2017-05-10 张四清 Digestion-promoting and stomach-strengthening tea
CN107890542A (en) * 2017-12-26 2018-04-10 湖南知达医药科技有限公司 Treat the Chinese medicine composition and its preparation method of diarrhoea
CN108402238A (en) * 2018-03-20 2018-08-17 重庆旭焰实业有限公司 A kind of honey citron tea and its preparation method and application
CN108669533A (en) * 2018-03-30 2018-10-19 杭州多源科技有限公司 A kind of meal replacing food and preparation method thereof of conditioning shield stomach
CN108379537A (en) * 2018-05-09 2018-08-10 丛念滋 A kind of infant's invigorating the spleen to arrest diarrhea herbaceous plant drink
CN112006137A (en) * 2020-09-17 2020-12-01 傅松涛 Spleen-tonifying and stomach-nourishing Su-radish tea and preparation method thereof

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