CN106071313A - A kind of feed additive for Carnis Coturnicis japonicae laying period and preparation method thereof - Google Patents

A kind of feed additive for Carnis Coturnicis japonicae laying period and preparation method thereof Download PDF

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CN106071313A
CN106071313A CN201610446990.0A CN201610446990A CN106071313A CN 106071313 A CN106071313 A CN 106071313A CN 201610446990 A CN201610446990 A CN 201610446990A CN 106071313 A CN106071313 A CN 106071313A
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herba
feed additive
raw
filtrate
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燕磊
吕明斌
唐婷婷
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Shandong New Hope Liuhe Group Co Ltd
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Shandong New Hope Liuhe Group Co Ltd
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Abstract

The invention discloses a kind of feed additive for Carnis Coturnicis japonicae laying period and preparation method thereof, wherein, feed additive includes following raw material: Massa Medicata Fermentata, Herba Saussureae Involueratae, Herba Cichorii, Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris, Foliumet Ramulus Evodiae, Fructus Mori, Herba Malvastri Coromandeliani, Rhizoma Polygonati Odorati, Ganoderma, hardship, Herba Polygoni Orientalis, DIGEN, Herba pterocephali, Lignum Pini Nodi, Semen Caesalpiniae Minacis and Xi.The invention has the beneficial effects as follows: the feed additive of the present invention can not only meet the nutritional need of Carnis Coturnicis japonicae, and Carnis Coturnicis japonicae egg production can be significantly improved and preferably prevent the generation of the disease such as food and dyspepsia disease, Hakuri, ulcerative enteritis, mycoplasma, bronchitis, constipation, product soft-shelled egg disease, there is obvious superiority, the raw material of the present invention is all natural product, has the advantages such as safety height, drug residue free, toxic and side effects.

Description

A kind of feed additive for Carnis Coturnicis japonicae laying period and preparation method thereof
Technical field
The present invention relates to Carnis Coturnicis japonicae feed additive, particularly to a kind of feed additive for Carnis Coturnicis japonicae laying period and Preparation method.
Background technology
Ovum Coturnicis japonicae has another name called quail bird egg, Carnis Coturnicis japonicae ovum.Ovum Coturnicis japonicae is considered as " Radix Ginseng in animal ".The most often food is nourishing dietetic therapy Product.Ovum Coturnicis japonicae nutritionally has unique distinction, therefore has the title of " good merchantable brand in ovum ".Subcircular, individuality is the least, the most only 5g Left and right, there is sepia speckle on surface.The nutritive value of Ovum Coturnicis japonicae is no less than egg, has preferable skin protection, skin Caring effect.Ovum Coturnicis japonicae is public Recognizing is a kind of cuisines, this little egg generally boil to well done or half-mature after shell, in salad, it is also possible to pickled, decocting in water or do Jelly food.Ovum Coturnicis japonicae is to there being the women of anemia, menoxenia, and it adjusts benefits, skin care, skin Caring function significantly, this is because Carnis Coturnicis japonicae Egg containing protein, cephalin, lecithin, lysine, cystine, vitamin a, vitamin b2, vitamin b1, vitamin d, ferrum, The nutrient substance such as phosphorus, calcium;Therefore quail crane raises development quickly, has become most economical poultry.Along with living standards of the people progressively Improving, Ovum Coturnicis japonicae demand gets more and more.
Laying rate is the important indicator during Carnis Coturnicis japonicae produces, and is the embodiment of Carnis Coturnicis japonicae economic benefit quality.Along with environmental factors Changing and the impact of disease, laying rate often becomes downward trend.Various places plant all occurs that Carnis Coturnicis japonicae laying rate declines or lays eggs now The problems such as the peak period persistent period is short.And along with growth in the living standard, people require the most increasingly for the mouthfeel of eggs Height, more people is ready to outbid to buy to raise the egg that Carnis Coturnicis japonicae produces scattered.Along with people are to meat and the demand of eggs, Carnis Coturnicis japonicae cultivation density Increasing, feedstuff consumption increases the most year by year, for the cultivation of Carnis Coturnicis japonicae, how to improve laying rate and reduces due to the big generation of cultivation density Various poultry diseases, become the focus of at present research.
Owing in existing feedstuff, great majority all can add antibiotic or the medicine containing antibiotic, although these additive energy Enough improve animal products specific yield and animal products quantity, but also create increasing negative effect, antibiotic simultaneously Use there is the drawbacks such as drug residue, drug resistance and cross infection, destroy the microbial balance in poultry body, cause poultry Fowl autogenous infection immunity, affects the normal growth promoter of poultry, affects the meat of Carnis Coturnicis japonicae and the nutritive value of Ovum Coturnicis japonicae simultaneously.
How to solve the problems referred to above, be then the problem that faced of the present invention.
Summary of the invention
In order to meet the nutritional need of Carnis Coturnicis japonicae, and Carnis Coturnicis japonicae egg production can be significantly improved and preferably prevent food and dyspepsia The generation of the diseases such as disease, Hakuri, ulcerative enteritis, mycoplasma, bronchitis, constipation, product soft-shelled egg disease, has significantly Superiority, the invention provides a kind of feed additive for Carnis Coturnicis japonicae laying period and preparation method thereof.
In order to realize foregoing invention purpose, the invention provides a kind of feed additive for Carnis Coturnicis japonicae laying period, wherein, Described feed additive includes following raw material: Massa Medicata Fermentata, Herba Saussureae Involueratae, Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris, Fructus Mori, Herba Malvastri Coromandeliani, jade Bamboo, Ganoderma, hardship, Herba Polygoni Orientalis, DIGEN, Semen Caesalpiniae Minacis and Xi.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 13-21 weight portion, Herba Saussureae Involueratae 15-35 weight Amount part, Caulis Tinosporae 10-20 weight portion, Fructus Aurantii Immaturus 15-25 weight portion, Radix Berberidis 10-30 weight portion, Herba Dracocephali Rupestris's 14-22 weight portion, Mulberry Mulberry 13-33 weight portion, Herba Malvastri Coromandeliani 14-28 weight portion, Rhizoma Polygonati Odorati 15-34 weight portion, Ganoderma 10-30 weight portion, bitter 11-21 weight Part, Herba Polygoni Orientalis 2-4 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 15-35 weight portion and Xi 11-27 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 14-20 weight portion, Herba Saussureae Involueratae 16-33 weight Amount part, Caulis Tinosporae 12-20 weight portion, Fructus Aurantii Immaturus 15-24 weight portion, Radix Berberidis 14-30 weight portion, Herba Dracocephali Rupestris's 14-20 weight portion, Mulberry Mulberry 15-32 weight portion, Herba Malvastri Coromandeliani 15-26 weight portion, Rhizoma Polygonati Odorati 18-33 weight portion, Ganoderma 10-30 weight portion, bitter 12-20 weight Part, Herba Polygoni Orientalis 2-3 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 18-35 weight portion and Xi 13-26 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, stretch Muscle rattan 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, Radix Berberidis 30 weight portion, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight Amount part, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight portion, bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portions and Xi 24 weight portion.
Described feed additive also includes that raw material is: Foliumet Ramulus Evodiae, Herba pterocephali, Lignum Pini Nodi and Herba Cichorii.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 13-21 weight portion, Herba Saussureae Involueratae 15-35 weight Amount part, Caulis Tinosporae 10-20 weight portion, Fructus Aurantii Immaturus 15-25 weight portion, Radix Berberidis 10-30 weight portion, Herba Dracocephali Rupestris's 14-22 weight portion, Mulberry Mulberry 13-33 weight portion, Herba Malvastri Coromandeliani 14-28 weight portion, Rhizoma Polygonati Odorati 15-34 weight portion, Ganoderma 10-30 weight portion, bitter 11-21 weight Part, Herba Polygoni Orientalis 2-4 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 15-35 weight portion, Xi 11-27 weight portion, Foliumet Ramulus Evodiae 3-5 weight portion, 10-26 weight portion, Herba pterocephali 15-35 weight portion, Lignum Pini Nodi 10-20 weight portion and Herba Cichorii 14-32 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, stretch Muscle rattan 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, Radix Berberidis 30 weight portion, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight Amount part, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight portion, bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portions, Xi 24 weight portion, Foliumet Ramulus Evodiae 4 weight portion, 24 weight portions, Herba pterocephali 33 weight portion, Lignum Pini Nodi 15 weight Part and Herba Cichorii 26 weight portion.
The dosage form of feed additive is powder, and its preparation method is:
The first step, mixes described raw material score ratio by weight, puts into pulverizer and carries out pulverizing or directly shredding, and loads to decoct and holds In device, add raw material or the raw material of directly chopping that suitable quantity of water makes its submergence pulverize, after soaking 30-50 minute, be heated to boiling After 30-50 minute, separating fried liquid, raw material slag again adds water and carries out decocting 2-3 time, respectively is isolated by fried liquid every time, merges All of fried liquid, then after filtering, take filtrate and abandon filtering residue;
Second step, after filtrate cools down, adding relative to the determining alcohol of liquid weight 1-2 times after concentrating is 80-90% ethanol, fills Dividing mix homogeneously, stand overnight so that it is precipitation, obtain filtrate after taking its supernatant liquid filtering next day, precipitate determining alcohol is 50- The ethanol of 60% is cleaned, and collects washing liquid and merges with filtrate, after ethanol is regained in decompression, stands 0.5-1 hour, makes precipitation complete, mistake Filter, filtrate low-temperature evaporation, it is thus achieved that paste;
3rd step: paste placed in spray dryer be dried, it is ensured that inlet temperature at 180 DEG C-200 DEG C, leaving air temp 70 DEG C-90 DEG C, it is ground into 200 mesh-300 mesh subsequently, it is thus achieved that powder.
The dosage form of feed additive is powder, and its preparation method is:
The first step, is mixed Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris and Fructus Mori in described ratio, with relative to the mixing obtained The ethanol that determining alcohol is 80%~90% of 3~5 times of material amount dissolves, and extracts after being heated to reflux 1~3 hour, filters, obtains first Filtrate;Filtering residue is dissolved with the ethanol of the determining alcohol 80%~90% of 1~2 times of the mixture quality relative to acquisition again, Extract after being heated to reflux 1~2 hour, filter, obtain the second filtrate;Merge the first filtrate and the second filtrate must mix filter Liquid, decompression recycling ethanol and be concentrated into mixing filter liquor concentration be 0.7~0.9g crude drug/mL, through the macroporous absorption tree that volume is 5L Fat post eluting, first with deionized water or the distilled water eluting of 5 times of resin column volumes, then with the determining alcohol of 3 times of resin column volumes be 80%~90% ethanol elution, collects ethanol elution, and concentrating under reduced pressure removes ethanol, is dried and is ground into powder;
Second step, is mixed DIGEN, Semen Caesalpiniae Minacis and Xi in described ratio, adds 2~4 relative to the mixture quality obtained The ethanol of determining alcohol 80%~90% again, heating and refluxing extraction 1~2 times, extracting solution merges, is centrifuged remove impurity with tube centrifuge, When extracting solution after remove impurity is evaporated under conditions of 60 DEG C~70 DEG C 60 DEG C, relative density is the cream of 1.20~1.23 Body, the mastic spray dryer after concentrating is dried to powder;
3rd step, is mixed surplus stock in described ratio, adds the water dissolution relative to 2~4 times of mixture quality obtained, Heating decocts 2~4 hours, filters;By filtering residue again with the water dissolution relative to 1~2 times of mixture quality obtained, again Heating decocts 1~2 hour, filters;Merging the filtrate of twice, concentrating under reduced pressure removes moisture, is dried and is ground into powder;
4th step, the powder mixing that the first step, second step and the 3rd step are obtained, it is screened into the fine powder of 80~120 mesh subsequently, will The fine powder obtained puts in mixing and blending machine and stirs, and i.e. obtains powder.
Described feed additive addition in feedstuff is interpolation 3-7g, the most every kilogram of feed in every kilogram of feed Middle interpolation 4-6g.
Technical solution of the present invention has the benefit that the feed additive of the present invention can not only meet the battalion of Carnis Coturnicis japonicae Foster demand, and Carnis Coturnicis japonicae egg production can be significantly improved and preferably prevent food and dyspepsia disease, Hakuri, ulcerative enteritis, prop up The generation of the diseases such as substance disease, bronchitis, constipation, product soft-shelled egg disease, has obvious superiority, and the raw material of the present invention is all Natural product, has the advantages such as safety height, drug residue free, toxic and side effects.
Detailed description of the invention
The invention provides a kind of feed additive for Carnis Coturnicis japonicae laying period, including following raw material: Massa Medicata Fermentata, Herba Saussureae Involueratae, Herba Cichorii, Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris, Foliumet Ramulus Evodiae, Fructus Mori, Herba Malvastri Coromandeliani, Rhizoma Polygonati Odorati, Ganoderma, hardship, Herba Polygoni Orientalis, DIGEN, , Herba pterocephali, Lignum Pini Nodi, Semen Caesalpiniae Minacis and Xi.
The characteristic of above-mentioned raw materials is as follows:
Xi: another name: Herba Patriniae, Thalaspi arvense L..Source: Cruciferae Xi platymiscium Xi Thlaspi arvense L., with Herb and seed are used as medicine.Spring and summer gathers herb, dries;Autumn in summer fruit picking branch, dries, lays seed.Nature and flavor: herb: bitter, sweet, flat. Cure mainly: herb: heat-clearing and toxic substances removing, inducing diuresis and reducing edema, and middle appetizing.For appendicitis, lung abscess, carbuncle furuncle and phyma poison, erysipelas, endometrium Inflammation, leucorrhea, nephritis, cirrhotic ascites, infantile dyspepsia.
Lignum Pini Nodi: source: predominantly Pinus tabulaeformis tabulaeformis Carr, is secondly 1. Pinus densifloras (short leaf Pinus densifloras) Pinus densiflora Sieb. et Zucc., 2. Folium seu Strobilus Pini sibiricae Pinus sibirica (Loud.) Mayr., 3. Pinus koraiensis (Korean pine) Pinus koraiensis Sieb. et Zucc., 4. Pinus armandi Franch-P. Komavovii Lavl. (Lignum Pini Nodi, five palpus pines) Pinus armandii Franch. the knob and the Lignum Pini Nodi of Pinus massoniana Lamb, pinus yunnanensis faranch, Pinus kesiya Royle ex Gordon var. langbianensis (A.Chev) Gaussen etc., or for pinaster grown after sick.The whole year can adopt, Dry.Nature and flavor: bitter, temperature.Cure mainly: expelling wind and removing dampness, activating collaterals to relieve pain.For rheumatic arthritis, lumbago and skelalgia, Kaschin-Beck disease, traumatic injury swells Bitterly.
: another name: Canis familiaris L. Pericarpium Zanthoxyli, Radix Zanthoxyli Avicennae [Fujian, Guangdong], chicken Hu, seed of Zanthoxylum armatum DC.(Z.Planispinum Sieb.et Zucc.) [Hainan], Zanthoxylum avicennae, Ramulus Kalopanacis seu Araliae [Guangdong, Guangxi].Source: Rutaceae xanthoxylum Zanthoxylum avicennae (Lam.) DC., with root, leaf It is used as medicine with fruit.Root can be adopted the whole year;Leaf can be adopted at any time;Really adopt winter, dry.Nature and flavor: bitter, pungent, tepor.Cure mainly: expelling wind and removing dampness, live Blood and relieving pain.Root: icterohepatitis, oedema due to nephritis, rheumatic arthritis.Really: stomachache, stomachache.Leaf: traumatic injury, lumbar muscle strain, Mastitis, furuncle and phyma.
Bitter: another name: Fructus Seu Herba Pubescentis, Herba seu Fructus Physalis Minimae, Herba seu Fructus Physalis Minimae, yellow Miss, little Calyx seu fructus physalis, Piao Piaocao, Da Epao.Source: Solanaceae Monkey flower hardship Physalis Pubescens L., with fruit, root or all herbal medicine.Xia Qiu gathers, using fresh herb or dry.Property Taste: bitter, cold.Cure mainly: heat-clearing and toxic substances removing, swelling diuretic.For laryngopharynx swelling and pain, parotitis, acute and chronic tracheitis, lung abscess, dysentery, Orchitis, dysuria;Impetigo is controlled in external.
Rhizoma Polygonati Odorati: another name: Rhizoma Polygonati Odorati, beautiful ginseng, tail ginseng, bell are as dish, little shaft of a writing brush dish, Herba Hedyotis cantonensis root, Kao Shanzhu.Source: this product is hundred The dry rhizome of conjunction section plant Rhizoma Polygonati Odorati Polygonatum odoratum (Mill.) Druce.Autumn excavates, and removes fibrous root, washes Only, shine to after softness, repeatedly rub, dry in the sun to without hard-core, dry;Or after steaming thoroughly, rub to translucent, dry.Nature and flavor: sweet, micro- Cold.Gui Jing: attach to the lung and stomach meridians.Cure mainly: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Hinder for lung stomach-Yin, cough caused by dryness-heat, dry throat and mouth, interior-heat Quench one's thirst.
Herba Polygoni Orientalis: source: for the aerial parts of polygonaceae plant smartweed Polygonum orientale L..Summer, autumn extract ground Upper part, after maybe laying Fructus Polygoni Orientalis, remaining aerial parts collects, and dries.Nature and flavor: pungent, temperature.Slightly poisonous.Cure mainly: Expelling wind and removing dampness, promoting blood circulation and stopping pain.For rheumatic arthritis.
Herba Malvastri Coromandeliani: another name: Coromadel Coast Falsemallow Herb, mountain Corchorus olitorius L., great Ye Hemerocallis citrina Baroni is violent, Prunus davidiana is young.Source: Malvaceae Herba Malvastri Coromandeliani platymiscium Herba Malvastri Coromandeliani Malvastrum coromandelium (L.) Garcke, with all herbal medicine.Autumn excavates, and cleans, and chopping is dried respectively.Property Taste: sweet, light is cool.Curing mainly: clearing away heat-damp and promoting diuresis, detoxify dissipating blood stasis.For enteritis of catching a cold, dysentery, icterohepatitis, rheumatic arthritis;Outward With controlling traumatic injury, furuncle, carbuncle.
Foliumet Ramulus Evodiae: source: " south of the Five Ridges gather medicinal herbs record ".Source: for the leaf that rutaceae three bifurcation is bitter.Can adopt at any time.Nature and flavor: Hardship, cold.1. " south of the Five Ridges gather medicinal herbs record ": " bitter in the mouth, cold in nature." 2. " Guangxi Chinese medicinal herbal ": " is bitter micro-pungent, cool, nontoxic." 3. " Yunnan medium-height grass Medicine selects ": " slightly poisonous." cure mainly: heat clearing away, removing toxic substances, dispel the wind, dehumidifying.Control laryngopharynx swelling and pain, malaria, icterohepatitis, rheumatic ostalgia, Eczema, dermatitis, skin infection.1. " south of the Five Ridges gather medicinal herbs record ": " heat clearing away poison.Control traumatic injury heating to have a pain." 2. " Nanning City's medicine will ": " heat clearing away Removing toxic substances, relaxing muscles and tendons and activating QI and blood in the collateral, wind-damp dispelling, antipruritic.Control traumatic injury, skin infection, malaria." 3. " Guangxi Chinese medicinal herbal ": " dispelling the wind and dampness pathogens osteodynia, sense Touch eruptive disease." 4. Guangzhou army " conventional Chinese herbal medicine handbook ": " heat-clearing and toxic substances removing, dampness removing to stop itchin.Prevent and treat influenza, epidemic encephalitis, encephalitis B; Treatment tonsillitis, pharyngolaryngitis, icterohepatitis, worm venom, furuncle and phyma, eczema, dermatitis, hemorrhoid."
Herba Dracocephali Rupestris: another name: Mao Jiancao, tippy tea, tippy tea.Source: Labiatae Herba Dracocephali Rupestris Dracocephalum rupestre Hance, with all herbal medicine.Nature and flavor: pungent are cool.Cure mainly: antipyretic antiinflammatory.Cure mainly headache due to pathogenic wind-dampness, laryngalgia cough, thoracic cavity distension.
Caulis Tinosporae: another name: Herba Lycopodii, the raw palpus (" Guangxi Chinese veterinarian's medicine is planted ") in nothing ground, blue or green Herba Lycopodii (" Luchuan is herbal "), cut Not dead (" Nanning City's medicine will "), relaxing muscles and tendons rattan (Guangzhou army " conventional Chinese herbal medicine handbook ").Source: " Nanning City's medicine will ".Come Source: for the stem of menispermaceous plants Tinospora sinensis.The whole year can adopt.Nature and flavor: " Nanning City's medicine will ": " bitter, cold." cure mainly: 1. " south Peaceful city medicine will ": " relaxing muscles and tendons and activating QI and blood in the collateral, parasite killing.External application traumatic injury tendon breaking, rheumatic ostalgia;Relaxing muscles and tendons and activating QI and blood in the collateral for oral administration." 2. Guangzhou army is " often Use Chinese herbal medicine handbook ": " relaxing muscles and tendons and activating QI and blood in the collateral, clearing away heat-damp and promoting diuresis.Dispelling the wind and dampness pathogens bones and muscles pain, lumbar muscle strain, traumatic injury."
Fructus Aurantii Immaturus: source: this product is rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety or Fructus Citri sinensis The dry young fruit of Citrus sinensis Osbeck.5~be collected from the fruit fallen June, remove impurity, crosscutting from middle part be Two halves, dry or cold drying, and smaller directly dries or cold drying.Nature and flavor: bitter, pungent, sour, temperature.Gui Jing: return spleen, stomach warp. Cure mainly: dispelling the stagnated QI removing food stagnancy, scattered painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, weight after dysentery, constipation, the expectorant stagnant vapour lock thoracic obstruction, Blocked-up chest;Gastroptosis, proctoptosis, uterine prolapse.
Massa Medicata Fermentata: source: " property of medicine opinion ".Source: after adding flour or wheat bran mixing for medicines such as Herba polygoni hydropiperis, Herba Artemisiae Annuae, Semen Armeniacae Amarums, through sending out The herbal leaven of ferment.Nature and flavor: sweet, acrid, warm.1. " pearl sac ": " pungent." 2. Materia Medica of Decoction: " hot air heating, sweet in the mouth." 3. " the southern regions of the Yunnan Province is originally Grass ": " property is put down, sweet in the mouth." 4. " detailed outline ": " sweet, acrid, warm, nontoxic." return through: enter spleen, stomach warp.1. Materia Medica of Decoction: " enter foot sun bright Warp." 2. " Thunder God concocts property of medicine solution ": " enters spleen, stomach two warp." 3. " book on Chinese herbal medicine is through solving ": " enters liver channel of foot-Jueyin, the stomach channel of foot-Yang-ming." Cure mainly: invigorating the spleen and regulating the stomach, help digestion in tune.Controlling retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen is hard Long-pending.1. " property of medicine opinion ": " digesting and absorbing the essence of foodstuff dyspepsia, crux stagnates, spleen invigorating warming the stomach." 2. Zhang Yuansu: " nourishing the stomach gas.Control also white chaste tree." 3. " soup Liquid book on Chinese herbal medicine ": " treating pathogenic wind in internal organs, the therapeutic method to keep the adverse QI flowing downwards in tune, whet the appetite the dyspepsia that disappears.Main cholera heart diaphragm gas, expectorant is inverse, relieving restlessness, broken crux and benefit Void, removes cold air, except the intestines and stomach is filled in, and not lower food.Children's's abdomen can be controlled hard greatly as dish, fullness in the chest, frequent fetal movement, or lumbago rob the heart, under Blood is more than." 4. " detailed outline ": " removing stagnancy of indigested food and making QI downward, expectorant lets out dysentery distension against cholera.Sprain lumbago person, forged wine decoction being taken warmly of quenching effective, woman People is intended to galactopoiesis person puerperal, and stir-fry is ground wine and taken two money, day two." 5. " book on Chinese herbal medicine is stated ": " cure the wound summer-heat, and being affected by fluid-retention is eaten, and hinders overstrain, and malaria flatulence due to stagnation of QI is demonstrate,proved, Edema distension gathers, cough due to fluid-retention, vomiting regurgitation, cholera, and blood-retention is pained, gastric abscess, hypochondriac pain, numbness flaccidity dizziness, heavy sensation of the body, it is impossible to Food, jaundice." 6. " book on Chinese herbal medicine is the newest ": " scrofula that disappears cellulitis tumor."
Semen Caesalpiniae Minacis: another name: Semen Caesalpiniae Minacis (" the SHENGCAO property of medicine is standby to be wanted "), crow medicated pillow (" medical material compilation of data "), soil Semen Caesalpiniae Minacis, blue or green Serpentis Son (" Nanning City's medicine will "), cat core (" Guangxi Chinese medicinal herbal "), wide Semen Caesalpiniae Minacis (" Traditional Chinese Medicine in Sichuan will ").Source: " revise and enlarge pseudo-medicine Bar is distinguished ".Source: for the seed of leguminous plant south Serpentis.8~JIUYUE between adopt mature fruit, take out seed, dry.Nature and flavor: bitter, Cold.1. " revise and enlarge pseudo-medicated strip to distinguish ": " taste is the most pained." 2. " Nanning City's medicine will ": " is bitter, cold, nontoxic." return through " Traditional Chinese Medicine in Sichuan Will ": " enter the heart, spleen, kidney three warp." cure mainly: dissipating blood stasis, pain relieving, heat clearing away, dry.Control hiccup, dysentery, stranguria with turbid discharge, hematuria, traumatic injury. 1. " the SHENGCAO property of medicine standby want ": " control traumatic injury wound, pain relieving, beat and rotten apply it." 2. " Guangxi wild resource plant ": " controls abnormal pigmentary deposit on the skin acute filthy disease."③ " Nanning City's medicine will ": " control skin infection, hematuria." 4. " Guangxi Chinese medicinal herbal ": " controls the cards such as fasting dysentery, nocturnal emission, stranguria with turbid discharge.Among the people with controlling Influenza." 5. " Traditional Chinese Medicine in Sichuan will ": " stimulating appetite, clear away heart-fire relieving restlessness, and dehumidifying is reduced phlegm and internal heat.Control hiccup more than." 6. " in Guangdong Medicine ": " control folder color typhoid fever;Decoct washing head leprosy."
DIGEN: another name: ground Radix Solani Melongenae (" Zhejiang conventional medical herbs among the people "), Herba Melastomatis dodecandri root (" the main poisonous plants in south ").Source: " south of the Five Ridges gather medicinal herbs record ".Source: for the root on Melastomateae plants ground.8~December gather.Nature and flavor: " east, Fujian book on Chinese herbal medicine ": " property is put down, taste Micro-sweet acid." return through: " east, Fujian book on Chinese herbal medicine ": " enters liver, kidney, spleen, lung four warp." cure mainly: invigorate blood circulation, hemostasis, dampness removing, removing toxic substances.Control dysmenorrhea, Puerperal abdonimal pain, metrorrhagia, leucorrhea, dysentery, scrofula, toothache.1. " Zhiwu Mingshi Tukao ": " control strain." 2. " south of the Five Ridges gather medicinal herbs record ": " Control puerperal abdonimal pain, dysentery with red and white feces." 3. " east, Fujian book on Chinese herbal medicine ": " can stop blooding and invigorate blood circulation, the hernia that disappears of detoxifying.Control dysmenorrhea, metrorrhagia and leukorrhagia, dysentery, hemorrhoid complicated by anal fistula, wind Rash, hernia." 4. Guangzhou army " conventional Chinese herbal medicine handbook ": " relieving dysentery with astringents, relaxing muscles and tendons and activating QI and blood in the collateral, enriching blood to prevent miscarriage.Control enteritis, bacillary dysentery; Lumbago and skelalgia, rheumatic ostalgia;Pregnant woman anemia, frequent fetal movement, menorrhagia." 5. " Fujian Chinese herbal medicine ": " invigorating the spleen and replenishing QI."
Fructus Mori: source: this product is the dry fruit ear of moraceae plants Mulberry Morus alba L..4~fruit in June gather when reddening, Dry, or slightly steam after dry.Nature and flavor: sweet, sour, cold.Gui Jing: GUIXIN, liver, kidney channel.Cure mainly: YIN nourishing of enriching blood, promote the production of body fluid and moisturize.For Vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
Herba Saussureae Involueratae: source: Compositae Genus Saussurea plant Saussurea laniceps Saussurea laniceps Hand.-Mazz. With Saussurea eriocephala S. eriocephala Franch, it is used as medicine with whole herb with root.Summer gathers, and Herb pulls up, and trembles clean silt, Dry.Nature and flavor: hardship sweet, micro-, temperature.Cure mainly: kidney invigorating and YANG supporting, regulating menstruation, hemostasis.For snow blindness, have a toothache, rheumatic arthritis, sexual impotence, Menoxenia, metrorrhagia, leucorrhea;Wound hemorrhage is controlled in external.
Herba Cichorii: source: this strain Uygur nationality conventional crude drugs.For feverfew saussurea intybus Cichorium Glandulosum Boiss.et Hout and the aerial parts of Herba Cichorii Cichorium intybus L..Autumn taps, and removes miscellaneous Matter, dries.Nature and flavor: micro-hardship, salty are cool.Cure mainly: liver heat removing function of gallbladder promoting, invigorating the stomach and promoting digestion, inducing diuresis to remove edema.For jaundice due to damp-heat, stomachache food Few, edema oliguria.
Herba pterocephali: another name: ear of maize head, lion grass.Source: Dipsacaceae wing head flower plant Radix Pterocephaili Pterocephalus hookeri (Clarke) Hoeck, is used as medicine with whole herb with root.It is complete that 7 the end of month took band root during alabastrum Grass, cleans cutting, dries.Nature and flavor: bitter, cold.Slightly poisonous.Curing mainly: clearing away heat and expelling pathogen in the exterior, clear away heart-fire removing heat from blood.For cold, fever and various The fever that epidemic febrile disease causes, in the heart dysphoria with smothery sensation, hemoptysis, spit blood, hematuria, have blood in stool.
Radix Berberidis: another name: draw point thorn (" Tian Bao book on Chinese herbal medicine "), Radix Berberidis soulieanae (" catalogue planted by Guizhou medicine ").Source: " classification medical herbs Property ".Source: for root bark or the peel of stem of Berberidaceae plant thorn black pearl, berberis brachypoda Maxim, black stone pearl etc..Root bark can be adopted the whole year.Peel of stem Spring, autumn gather, and take stem branch and scrape off crust, strip the endothelium of buff.Dry.Nature and flavor: " Traditional Chinese Medicine in Sichuan will ": " cold in nature, micro- Hardship, nontoxic." cure mainly: heat clearing away, dampness removing, dissipating blood stasis.Control bloody dysentery, jaundice, pharyngalgia, conjunctival congestion, traumatic injury.1. " classify herbal ": " Control traumatic injury, over-strained hemoptysis." 2. " Traditional Chinese Medicine in Sichuan will ": " heat-clearing and toxic substances removing, antiphlogistic antibacterial.Control conjunctival congestion, bloody dysentery, haematemesis impairment caused by overstrain, Laryngopharynx swelling and pain, diarrhoea, toothache, earache, traumatic injury is red and swollen." 3. " Guizhou medical herbs ": " is antipyretic, dampness removing, dissipating blood stasis, and pain relieving is cool Blood."
Ganoderma: another name: Ganoderma lucidum seu Japonicum, Ganoderma, Ganoderma Lucidum.Source: this product is On Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Ganoderma Lucidum(Leyss.ex Fr.) the dry son of Karst. or Ganoderma Ganoderma sinense Zhao, Xu et Zhang is real Body.The whole year gathers, and removes impurity, wipes out the lower end stem with rotten wood, silt or culture matrix, dry in the shade or 40~50 DEG C of bakings Dry.Nature and flavor: sweet are flat.Gui Jing: GUIXIN, lung, liver, kidney channel.Cure mainly: invigorating QI and tranquilization, relieving cough and asthma.For dizziness sleeplessness, cardiopalmus gas Short, asthenia cough with asthma.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 13-21 weight portion, Herba Saussureae Involueratae 15-35 weight Amount part, Caulis Tinosporae 10-20 weight portion, Fructus Aurantii Immaturus 15-25 weight portion, Radix Berberidis 10-30 weight portion, Herba Dracocephali Rupestris's 14-22 weight portion, Mulberry Mulberry 13-33 weight portion, Herba Malvastri Coromandeliani 14-28 weight portion, Rhizoma Polygonati Odorati 15-34 weight portion, Ganoderma 10-30 weight portion, bitter 11-21 weight Part, Herba Polygoni Orientalis 2-4 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 15-35 weight portion and Xi 11-27 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 14-20 weight portion, Herba Saussureae Involueratae 16-33 weight Amount part, Caulis Tinosporae 12-20 weight portion, Fructus Aurantii Immaturus 15-24 weight portion, Radix Berberidis 14-30 weight portion, Herba Dracocephali Rupestris's 14-20 weight portion, Mulberry Mulberry 15-32 weight portion, Herba Malvastri Coromandeliani 15-26 weight portion, Rhizoma Polygonati Odorati 18-33 weight portion, Ganoderma 10-30 weight portion, bitter 12-20 weight Part, Herba Polygoni Orientalis 2-3 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 18-35 weight portion and Xi 13-26 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, stretch Muscle rattan 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, Radix Berberidis 30 weight portion, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight Amount part, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight portion, bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portions and Xi 24 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 13-21 weight portion, Herba Saussureae Involueratae 15-35 weight Amount part, Caulis Tinosporae 10-20 weight portion, Fructus Aurantii Immaturus 15-25 weight portion, Radix Berberidis 10-30 weight portion, Herba Dracocephali Rupestris's 14-22 weight portion, Mulberry Mulberry 13-33 weight portion, Herba Malvastri Coromandeliani 14-28 weight portion, Rhizoma Polygonati Odorati 15-34 weight portion, Ganoderma 10-30 weight portion, bitter 11-21 weight Part, Herba Polygoni Orientalis 2-4 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 15-35 weight portion, Xi 11-27 weight portion, Foliumet Ramulus Evodiae 3-5 weight portion, 10-26 weight portion, Herba pterocephali 15-35 weight portion, Lignum Pini Nodi 10-20 weight portion and Herba Cichorii 14-32 weight portion.
Described feed additive is made up of the raw material of following parts by weight: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, stretch Muscle rattan 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, Radix Berberidis 30 weight portion, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight Amount part, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight portion, bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portions, Xi 24 weight portion, Foliumet Ramulus Evodiae 4 weight portion, 24 weight portions, Herba pterocephali 33 weight portion, Lignum Pini Nodi 15 weight Part and Herba Cichorii 26 weight portion.
The dosage form of feed additive is powder, and its preparation method is:
The first step, mixes described raw material score ratio by weight, puts into pulverizer and carries out pulverizing or directly shredding, and loads to decoct and holds In device, add raw material or the raw material of directly chopping that suitable quantity of water makes its submergence pulverize, after soaking 30-50 minute, be heated to boiling After 30-50 minute, separating fried liquid, raw material slag again adds water and carries out decocting 2-3 time, respectively is isolated by fried liquid every time, merges All of fried liquid, then after filtering, take filtrate and abandon filtering residue;
Second step, after filtrate cools down, adding relative to the determining alcohol of liquid weight 1-2 times after concentrating is 80-90% ethanol, fills Dividing mix homogeneously, stand overnight so that it is precipitation, obtain filtrate after taking its supernatant liquid filtering next day, precipitate determining alcohol is 50- The ethanol of 60% is cleaned, and collects washing liquid and merges with filtrate, after ethanol is regained in decompression, stands 0.5-1 hour, makes precipitation complete, mistake Filter, filtrate low-temperature evaporation, it is thus achieved that paste;
3rd step: paste placed in spray dryer be dried, it is ensured that inlet temperature at 180 DEG C-200 DEG C, leaving air temp 70 DEG C-90 DEG C, it is ground into 200 mesh-300 mesh subsequently, it is thus achieved that powder.
The dosage form of feed additive is powder, and its preparation method is:
The first step, is mixed Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris and Fructus Mori in described ratio, with relative to the mixing obtained The ethanol that determining alcohol is 80%~90% of 3~5 times of material amount dissolves, and extracts after being heated to reflux 1~3 hour, filters, obtains first Filtrate;Filtering residue is dissolved with the ethanol of the determining alcohol 80%~90% of 1~2 times of the mixture quality relative to acquisition again, Extract after being heated to reflux 1~2 hour, filter, obtain the second filtrate;Merge the first filtrate and the second filtrate must mix filter Liquid, decompression recycling ethanol and be concentrated into mixing filter liquor concentration be 0.7~0.9g crude drug/mL, through the macroporous absorption tree that volume is 5L Fat post eluting, first with deionized water or the distilled water eluting of 5 times of resin column volumes, then with the determining alcohol of 3 times of resin column volumes be 80%~90% ethanol elution, collects ethanol elution, and concentrating under reduced pressure removes ethanol, is dried and is ground into powder;
Second step, is mixed DIGEN, Semen Caesalpiniae Minacis and Xi in described ratio, adds 2~4 relative to the mixture quality obtained The ethanol of determining alcohol 80%~90% again, heating and refluxing extraction 1~2 times, extracting solution merges, is centrifuged remove impurity with tube centrifuge, When extracting solution after remove impurity is evaporated under conditions of 60 DEG C~70 DEG C 60 DEG C, relative density is the cream of 1.20~1.23 Body, the mastic spray dryer after concentrating is dried to powder;
3rd step, is mixed surplus stock in described ratio, adds the water dissolution relative to 2~4 times of mixture quality obtained, Heating decocts 2~4 hours, filters;By filtering residue again with the water dissolution relative to 1~2 times of mixture quality obtained, again Heating decocts 1~2 hour, filters;Merging the filtrate of twice, concentrating under reduced pressure removes moisture, is dried and is ground into powder;
4th step, the powder mixing that the first step, second step and the 3rd step are obtained, it is screened into the fine powder of 80~120 mesh subsequently, will The fine powder obtained puts in mixing and blending machine and stirs, and i.e. obtains powder.
Hereinafter using embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve whereby Certainly technical problem, and the process that realizes reaching technique effect can fully understand and implement according to this.
Embodiment 1 feed additive 1
Embodiments providing a kind of feed additive for Carnis Coturnicis japonicae laying period, described feed additive is by following weight The raw material of number is made: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, Caulis Tinosporae 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, Radix Berberidis 30 weight portions, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight portion, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight portion, Bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portion and Xi 24 weight portion;
Its preparation method is:
The first step, mixes described raw material score ratio by weight, puts into pulverizer and pulverizes, and loads and decocts in container, adds Suitable quantity of water makes the raw material that its submergence is pulverized, and after soaking 35 minutes, after being heated to seething with excitement 40 minutes, separates fried liquid, and raw material slag is again Secondary adding water carries out decocting 2 times, respectively is isolated by fried liquid every time, merges all of fried liquid, then after filtering, takes filtrate and abandon Filtering residue;
Second step, after filtrate cools down, adding relative to the determining alcohol of liquid weight 1.5 times after concentrating is 85% ethanol, the most mixed Closing uniformly, stand overnight so that it is precipitation, obtain filtrate after taking its supernatant liquid filtering next day, precipitate determining alcohol is the second of 55% Alcohol is cleaned, and collects washing liquid and merges with filtrate, after ethanol is regained in decompression, stands 0.5 hour, makes precipitation complete, filters, and filtrate is low Temperature evaporation, it is thus achieved that paste;
3rd step: paste placed in spray dryer be dried, it is ensured that inlet temperature at 190 DEG C, leaving air temp 80 DEG C, subsequently It is ground into 300 mesh, it is thus achieved that powder.
Above-mentioned feed additive addition in feedstuff is interpolation 3g in every kilogram of feed.
Embodiment 2 feed additive 2
The invention provides a kind of feed additive for Carnis Coturnicis japonicae laying period, described feed additive is by following parts by weight Raw material is made: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, Caulis Tinosporae 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, Radix Berberidis 30 weight Part, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight portion, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight portion, hardship 18 Weight portion, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portion, Xi 24 weight portion, Foliumet Ramulus Evodiae 4 weight Part, 24 weight portions, Herba pterocephali 33 weight portion, Lignum Pini Nodi 15 weight portion and Herba Cichorii 26 weight portion;
Its preparation method is:
The first step, is mixed Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris and Fructus Mori in described ratio, with relative to the mixing obtained The ethanol that determining alcohol is 85% of 4 times of material amount dissolves, and extracts after being heated to reflux 2 hours, filters, obtains the first filtrate;Will filter Slag dissolves with the ethanol of the determining alcohol 85% of 1.5 times of the mixture quality relative to acquisition again, carries after being heated to reflux 2 hours Take, filter, obtain the second filtrate;Merging the first filtrate and the second filtrate must mix filtrate, decompression recycling ethanol also concentrates It is 0.8g crude drug/mL to mixing filter liquor concentration, through the macroporous adsorptive resins eluting that volume is 5L, first with 5 times of resin column volumes Deionized water or distilled water eluting, then be 85% ethanol elution with the determining alcohol of 3 times of resin column volumes, collect ethanol elution Liquid, concentrating under reduced pressure removes ethanol, is dried and is ground into powder;
Second step, is mixed DIGEN, Semen Caesalpiniae Minacis and Xi in described ratio, adds 3 times relative to the mixture quality obtained The ethanol of determining alcohol 85%, heating and refluxing extraction 1.5 times, extracting solution merges, is centrifuged remove impurity with tube centrifuge, after remove impurity Extracting solution when being evaporated to 60 DEG C under conditions of 65 DEG C relative density be the mastic of 1.22, the mastic after concentrating sprays Mist exsiccator is dried to powder;
3rd step, is mixed surplus stock in described ratio, adds the water dissolution relative to 3 times of mixture quality obtained, adds Heat decocts 4 hours, filters;By filtering residue again with the water dissolution of 1.5 times of the mixture quality relative to acquisition, again heat and decoct Boil 2 hours, filter;Merging the filtrate of twice, concentrating under reduced pressure removes moisture, is dried and is ground into powder;
4th step, the powder mixing that the first step, second step and the 3rd step are obtained, it is screened into the fine powder of 100 mesh subsequently, will obtain Fine powder put in mixing and blending machine and stir, i.e. obtain powder.
Above-mentioned feed additive addition in feedstuff is interpolation 5g in every kilogram of feed.
Toxicity test
(1) application NIH mice 40, SPF level, male and female half and half, body weight 18~22g, carry out acute toxicity test.Mice is divided at random It is two groups, often group 20, i.e. matched group and administration group, fasting 12 hours before experiment;Feedstuff prepared by embodiments of the invention 1 Additive 1 is dissolved in water, and (concentration is 6.58g crude drug/ml, maximum concentration) gavage, gavage volume is that 5ml/kg(i.e. single is given Pharmaceutical quantities is 32.9 crude drugs/kg), matched group gives normal saline, within one day, is administered 2 times, delivery time 6 hours, gives Continuous Observation 14 days after medicine, and record mice toxic reaction and death toll.Test result indicate that: compare with matched group, give After medicine, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase the most normal.
(2) feed additive of the embodiment of the present invention 2 is used to mice by 10.78,20.35 and 33.48g crude drugs/kg even After continuous 16 weeks (1.0ml/100g body weight, every day 2 times) of medication and drug withdrawal 4 weeks, result shows: the Chinese medicine of the present invention hair to mice Send out, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, the index such as blood fat all have no significant effect, internal organs meat Eye does not find that difference change and histological indications show, after medication 16 weeks and drug withdrawal 4 weeks, Organs of Mice is all without obvious Change.Illustrate that feed additive of the present invention is little to toxicity after mice long-term prescription, after drug withdrawal, also there is no difference reaction, application peace Entirely.
Contrast test:
Gaotang County, Liaocheng of Shandong Province Carnis Coturnicis japonicae plant, in by the end of December, 2014, by be in laying period and healthy 300, female, Male ratio is 1:1, is randomly divided into three experimental grouies, often organizes 100, respectively embodiment 1 group, embodiment 2 groups and matched group, this Using the feed additive 1 addition in conventional feed in inventive embodiments 1 group is interpolation 3g, embodiment in every kilogram of feed Using the feed additive 2 addition in conventional feed in 2 groups is interpolation 5g in every kilogram of feed, and matched group uses tradition to raise Material is fed, and three experimental grouies are fed 35 days continuously, adds up the quantity of laying eggs of the 15-24 days after laying eggs, egg size amount, fragmentation The quantity of egg, the morbidity quantity of various diseases, and randomly draw 10 Ovum Coturnicis japonicae, and the thickness of detection Carnis Coturnicis japonicae eggshell, Ovum Coturnicis japonicae The content of various nutritional labelings, and calculate the average thickness of Ovum Coturnicis japonicae eggshell, averagely containing of the various nutritional labeling of Ovum Coturnicis japonicae Amount;Result of the test is as follows:
Table 1 is that the Carnis Coturnicis japonicae of each group lays eggs quantity, egg size amount and the quantity of fragmentation egg:
Group Quantity of laying eggs (piece) Egg size amount (kg) The quantity (individual) of fragmentation egg
Matched group 872 43.9 54
Embodiment 1 group 970 54.27 22
Embodiment 2 groups 987 69.45 17
From the data of table 1 it can be seen that compared with the Carnis Coturnicis japonicae using tradition quail feed to feed, use and be added with present invention enforcement The Carnis Coturnicis japonicae of the forage feed of the additive of 1 group-embodiment of example 2 groups, its quantity of laying eggs, egg size amount are all higher than matched group, fragmentation egg Quantity significantly lower than matched group, so the quail feed additive that 1 group-embodiment of the embodiment of the present invention 2 groups provides can carry Lay eggs quantity and the egg size amount of high Carnis Coturnicis japonicae, reduces the quantity of fragmentation egg;It can thus be appreciated that this feed additive is through this preparation method Make make with common process technique compared with, alimentation is effective, has obvious superiority.
Table 2 is morbidity quantitative comparison's situation of the various disease of Carnis Coturnicis japonicae of each group:
Group Anorexia is sick (only) with dyspepsia Hakuri (only) Ulcerative enteritis (only) Mycoplasma (only) Bronchitis (only) Constipation (only) Produce soft-shelled egg sick (only)
Matched group 5 4 7 5 6 9 6
Embodiment 1 group 1 0 1 1 2 2 3
Embodiment 2 groups 0 0 0 0 0 1 0
Data from table 2: compared with the Carnis Coturnicis japonicae that conventional feed is fed, use 1 group-embodiment of the embodiment of the present invention 2 groups The Carnis Coturnicis japonicae of the forage feed of additive, wherein, food and dyspepsia disease, Hakuri, ulcerative enteritis, mycoplasma, bronchitis, just Secret, to produce soft-shelled egg sick sickness rate is significantly less than matched group, illustrates that the feed ratio conventional feed being added with this feed additive has The most prophylactic effect;Illustrate that this feed additive ingredient draws is more preferable, it is possible to preferably prevention food is sick with dyspepsia, white The generation of the diseases such as dysentery disease, ulcerative enteritis, mycoplasma, bronchitis, constipation, product soft-shelled egg disease, has the most superior Property.
Table 3 is the thickness (10 Ovum Coturnicis japonicae of extraction, unit mm) of the Carnis Coturnicis japonicae eggshell of each group:
Group 1 2 3 4 5 6 7 8 9 10 Meansigma methods
Matched group 0.37 0.34 0.47 0.35 0.36 0.33 0.38 0.37 0.32 0.33 3.98
Embodiment 1 group 0.42 0.44 0.51 0.43 0.45 0.39 0.41 0.42 0.37 0.49 0.43
Embodiment 2 groups 0.45 0.61 0.67 0.55 0.58 0.59 0.53 0.47 0.63 0.65 0.52
From the data of table 3 it can be seen that compared with the Carnis Coturnicis japonicae using tradition quail feed to feed, use and be added with present invention enforcement The Carnis Coturnicis japonicae of the forage feed of the additive of 1 group-embodiment of example 2 groups, its shell thickness laid eggs is better than matched group, and explanation is added with Feed additive of the present invention meets the nutritional need of Carnis Coturnicis japonicae, has obvious superiority.
Table 4 is the Analysis of Nutritive Composition (10 Ovum Coturnicis japonicae of extraction) of the Ovum Coturnicis japonicae of each group
Group Weight (g) Protein (g) Fat (g) Carbohydrate (g) Riboflavin Vitamin (ug) Energy (kilocalorie)
Matched group 49.71 7.53 5.63 1.09 0.27 173.65 84.07
Embodiment 1 group 67.12 9.94 6.96 1.30 0.43 179.03 107.32
Embodiment 2 groups 69.04 10.35 7.28 1.49 0.49 195.46 115.96
From the data of table 4 it can be seen that compared with the Carnis Coturnicis japonicae using tradition quail feed to feed, use and be added with present invention enforcement The Carnis Coturnicis japonicae of the forage feed of the additive of 1 group-embodiment of example 2 groups, the weight of Ovum Coturnicis japonicae, protein, fat, carbohydrate, Riboflavin, vitamin and energy have obvious superiority.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.

Claims (9)

1. the feed additive for Carnis Coturnicis japonicae laying period, it is characterised in that described feed additive includes following raw material: god Song, Herba Saussureae Involueratae, Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris, Fructus Mori, Herba Malvastri Coromandeliani, Rhizoma Polygonati Odorati, Ganoderma, hardship, Herba Polygoni Orientalis, DIGEN, bitter stone Lotus and Xi.
Feed additive the most according to claim 1, it is characterised in that described feed additive is by following parts by weight Raw material is made: Massa Medicata Fermentata 13-21 weight portion, Herba Saussureae Involueratae 15-35 weight portion, Caulis Tinosporae 10-20 weight portion, Fructus Aurantii Immaturus 15-25 weight portion, Radix Berberidis 10-30 weight portion, Herba Dracocephali Rupestris's 14-22 weight portion, Fructus Mori 13-33 weight portion, Herba Malvastri Coromandeliani 14-28 weight portion, Rhizoma Polygonati Odorati 15-34 Weight portion, Ganoderma 10-30 weight portion, bitter 11-21 weight portion, Herba Polygoni Orientalis 2-4 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 15-35 weight portion and Xi 11-27 weight portion.
Feed additive the most according to claim 1 and 2, it is characterised in that described feed additive is by following weight portion The raw material of number is made: Massa Medicata Fermentata 14-20 weight portion, Herba Saussureae Involueratae 16-33 weight portion, Caulis Tinosporae 12-20 weight portion, Fructus Aurantii Immaturus 15-24 weight Amount part, Radix Berberidis 14-30 weight portion, Herba Dracocephali Rupestris's 14-20 weight portion, Fructus Mori 15-32 weight portion, Herba Malvastri Coromandeliani 15-26 weight portion, Rhizoma Polygonati Odorati 18-33 weight portion, Ganoderma 10-30 weight portion, bitter 12-20 weight portion, Herba Polygoni Orientalis 2-3 weight portion, DIGEN 10-20 weight portion, Semen Caesalpiniae Minacis 18-35 weight portion and Xi 13-26 weight portion.
4. according to the feed additive described in any one of claim 1-3, it is characterised in that described feed additive is by following heavy Amount number raw material make: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, Caulis Tinosporae 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, three Pin 30 weight portion, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight portion, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight Part, bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portion and Xi 24 weight portion.
5. according to the feed additive described in any one of claim 1-4, it is characterised in that described feed additive also includes former Material is: Foliumet Ramulus Evodiae, Herba pterocephali, Lignum Pini Nodi and Herba Cichorii.
6. according to the feed additive described in any one of claim 1-5, it is characterised in that described feed additive is by following heavy The raw material of amount number is made: Massa Medicata Fermentata 13-21 weight portion, Herba Saussureae Involueratae 15-35 weight portion, Caulis Tinosporae 10-20 weight portion, Fructus Aurantii Immaturus 15- 25 weight portions, Radix Berberidis 10-30 weight portion, Herba Dracocephali Rupestris's 14-22 weight portion, Fructus Mori 13-33 weight portion, Herba Malvastri Coromandeliani 14-28 weight portion, Rhizoma Polygonati Odorati 15-34 weight portion, Ganoderma 10-30 weight portion, bitter 11-21 weight portion, Herba Polygoni Orientalis 2-4 weight portion, DIGEN 10-20 weight Part, Semen Caesalpiniae Minacis 15-35 weight portion, Xi 11-27 weight portion, Foliumet Ramulus Evodiae 3-5 weight portion, 10-26 weight portion, Herba pterocephali 15-35 weight portion, Lignum Pini Nodi 10-20 weight portion and Herba Cichorii 14-32 weight portion.
7. according to the feed additive described in any one of claim 1-6, it is characterised in that described feed additive is by following heavy Amount number raw material make: Massa Medicata Fermentata 16 weight portion, Herba Saussureae Involueratae 32 weight portion, Caulis Tinosporae 20 weight portion, Fructus Aurantii Immaturus 16 weight portion, three Pin 30 weight portion, Herba Dracocephali Rupestris 15 weight portion, Fructus Mori 30 weight portion, Herba Malvastri Coromandeliani 24 weight portion, Rhizoma Polygonati Odorati 32 weight portion, Ganoderma 25 weight Part, bitter 18 weight portions, Herba Polygoni Orientalis 2 weight portion, DIGEN 15 weight portion, Semen Caesalpiniae Minacis 33 weight portion, Xi 24 weight portion, three bifurcations hardships Leaf 4 weight portion, 24 weight portions, Herba pterocephali 33 weight portion, Lignum Pini Nodi 15 weight portion and Herba Cichorii 26 weight portion.
8. according to the feed additive described in any one of claim 1-7, it is characterised in that the dosage form of feed additive is powder Agent, its preparation method is:
The first step, mixes described raw material score ratio by weight, puts into pulverizer and carries out pulverizing or directly shredding, and loads to decoct and holds In device, add raw material or the raw material of directly chopping that suitable quantity of water makes its submergence pulverize, after soaking 30-50 minute, be heated to boiling After 30-50 minute, separating fried liquid, raw material slag again adds water and carries out decocting 2-3 time, respectively is isolated by fried liquid every time, merges All of fried liquid, then after filtering, take filtrate and abandon filtering residue;
Second step, after filtrate cools down, adding relative to the determining alcohol of liquid weight 1-2 times after concentrating is 80-90% ethanol, fills Dividing mix homogeneously, stand overnight so that it is precipitation, obtain filtrate after taking its supernatant liquid filtering next day, precipitate determining alcohol is 50- The ethanol of 60% is cleaned, and collects washing liquid and merges with filtrate, after ethanol is regained in decompression, stands 0.5-1 hour, makes precipitation complete, mistake Filter, filtrate low-temperature evaporation, it is thus achieved that paste;
3rd step: paste placed in spray dryer be dried, it is ensured that inlet temperature at 180 DEG C-200 DEG C, leaving air temp 70 DEG C-90 DEG C, it is ground into 200 mesh-300 mesh subsequently, it is thus achieved that powder.
9. the preparation method of the feed additive as described in any one of claim 1-7, it is characterised in that feed additive Dosage form be powder, its preparation method is:
The first step, is mixed Caulis Tinosporae, Fructus Aurantii Immaturus, Radix Berberidis, Herba Dracocephali Rupestris and Fructus Mori in described ratio, with relative to the mixing obtained The ethanol that determining alcohol is 80%~90% of 3~5 times of material amount dissolves, and extracts after being heated to reflux 1~3 hour, filters, obtains first Filtrate;Filtering residue is dissolved with the ethanol of the determining alcohol 80%~90% of 1~2 times of the mixture quality relative to acquisition again, Extract after being heated to reflux 1~2 hour, filter, obtain the second filtrate;Merge the first filtrate and the second filtrate must mix filter Liquid, decompression recycling ethanol and be concentrated into mixing filter liquor concentration be 0.7~0.9g crude drug/mL, through the macroporous absorption tree that volume is 5L Fat post eluting, first with deionized water or the distilled water eluting of 5 times of resin column volumes, then with the determining alcohol of 3 times of resin column volumes be 80%~90% ethanol elution, collects ethanol elution, and concentrating under reduced pressure removes ethanol, is dried and is ground into powder;
Second step, is mixed DIGEN, Semen Caesalpiniae Minacis and Xi in described ratio, adds 2~4 relative to the mixture quality obtained The ethanol of determining alcohol 80%~90% again, heating and refluxing extraction 1~2 times, extracting solution merges, is centrifuged remove impurity with tube centrifuge, When extracting solution after remove impurity is evaporated under conditions of 60 DEG C~70 DEG C 60 DEG C, relative density is the cream of 1.20~1.23 Body, the mastic spray dryer after concentrating is dried to powder;
3rd step, is mixed surplus stock in described ratio, adds the water dissolution relative to 2~4 times of mixture quality obtained, Heating decocts 2~4 hours, filters;By filtering residue again with the water dissolution relative to 1~2 times of mixture quality obtained, again Heating decocts 1~2 hour, filters;Merging the filtrate of twice, concentrating under reduced pressure removes moisture, is dried and is ground into powder;
4th step, the powder mixing that the first step, second step and the 3rd step are obtained, it is screened into the fine powder of 80~120 mesh subsequently, will The fine powder obtained puts in mixing and blending machine and stirs, and i.e. obtains powder.
CN201610446990.0A 2016-06-21 2016-06-21 A kind of feed additive for Carnis Coturnicis japonicae laying period and preparation method thereof Pending CN106071313A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107156521A (en) * 2017-06-22 2017-09-15 湖南天柱山禽业综合开发有限公司 A kind of laying hen special feed and preparation method thereof

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CN103461694A (en) * 2013-08-09 2013-12-25 江苏农林职业技术学院 Chinese herbal medicinal additive for improving laying rate of quails, and preparation method and application thereof
CN104171739A (en) * 2014-08-22 2014-12-03 徐州福润禽业食品有限公司 Traditional Chinese medicine compound feed for egg quails and preparation method thereof
CN104489385A (en) * 2014-12-19 2015-04-08 天津万达嘉禾饲料有限公司 Chinese-herbal-medicine feed for quails

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103461694A (en) * 2013-08-09 2013-12-25 江苏农林职业技术学院 Chinese herbal medicinal additive for improving laying rate of quails, and preparation method and application thereof
CN104171739A (en) * 2014-08-22 2014-12-03 徐州福润禽业食品有限公司 Traditional Chinese medicine compound feed for egg quails and preparation method thereof
CN104489385A (en) * 2014-12-19 2015-04-08 天津万达嘉禾饲料有限公司 Chinese-herbal-medicine feed for quails

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107156521A (en) * 2017-06-22 2017-09-15 湖南天柱山禽业综合开发有限公司 A kind of laying hen special feed and preparation method thereof

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Application publication date: 20161109