CN103689561A - Health-preserving health food formula beneficial for reducing lipid and losing weight and preparation method thereof - Google Patents
Health-preserving health food formula beneficial for reducing lipid and losing weight and preparation method thereof Download PDFInfo
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- CN103689561A CN103689561A CN201210367132.9A CN201210367132A CN103689561A CN 103689561 A CN103689561 A CN 103689561A CN 201210367132 A CN201210367132 A CN 201210367132A CN 103689561 A CN103689561 A CN 103689561A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention relates to a health-preserving health food formula beneficial for reducing lipid and losing weight and a preparation method thereof. The health-preserving health food formula comprises the following raw materials in parts by weight: 1000 parts of medlar, 1000 parts of rhizoma polygonati, 1000 parts of poria cocos, 1500 parts of rhizoma dioscoreae, 1000 parts of mulberry, 1000 parts of hawthorn, 1200 parts of semen cassiae, 600 parts of lotus leaves, 700 parts of chrysanthemum, and 1000 parts of semen raphani. The health-preserving health food formula can help to reduce blood lipid and reduce body fat, and is suitable for simple obesity, hypertension, hyperlipidemia and hyperglycemia groups.
Description
Technical field
The invention discloses a kind of health preserving health-care food formula that contributes to lowering blood-fat and reducing weight and preparation method thereof.
Background technology
Along with the change of people's diet structure and life style, obesity has become worldwide epidemic disease.Fat when affecting people's image appearance, also increased the incidence of disease of various diseases.Drug therapy is the conventional means of Bariatric, and various panoramic slimming drugs appear at people's the visual field now, when people to lose weight is bought, and its side effect bringing worry that also induces one.That the present invention aims to provide a kind of formula is simple, the curative effect double effects of significantly losing weight, keep healthy, fat-weight-reducing food.
Summary of the invention
The object of this invention is to provide a kind of health preserving health-care food formula that contributes to lowering blood-fat and reducing weight and preparation method thereof.
The present invention is made by the raw material of following portions by weight: fruit of Chinese wolfberry 600-1400 part, sealwort 600-1500 part, Poria cocos 600-1500 part, Chinese yam 1000-2000 part, mulberry fruit 800-1300 part, hawthorn 800-1200 part, cassia seed 900-1500 part, lotus leaf 300-1000 part, chrysanthemum 500-1000 part, radish seed 500-1200 part.
Better weight proportion of the present invention is: fruit of Chinese wolfberry 700-1300 part, sealwort 700-1400 part, Poria cocos 700-1400 part, Chinese yam 1200-1800 part, mulberry fruit 900-1200 part, hawthorn 900-1100 part, cassia seed 1000-1400 part, lotus leaf 400-900 part, chrysanthemum 600-900 part, radish seed 600-1100 part.
The optimum weight proportioning of each composition is above: 1000 parts of the fruits of Chinese wolfberry, 1000 parts of sealworts, 1000 parts, Poria cocos, 1500 parts of Chinese yams, 1000 parts, mulberry fruit, 1000 parts of hawthorn, 1200 parts of cassia seeds, 600 parts, lotus leaf, 700 parts of chrysanthemums, 1000 parts of radish seeds.
Preparation method of the present invention comprises the following steps:
(1) each medicinal material in formula is placed in to boil carries pot, infiltrate 30 minutes, then add the deionized water of 10 times of amounts, soaking at room temperature 2 hours; Then be heated to boiling, boil and extract 2 hours, the water outlet extract that inclines, filters;
(2) again add the deionized water of 10 times of amounts of medicinal material, boil and extract 2 hours, the water outlet extract that inclines, filters;
(3) combining step (1), (2) gained filtrate, cooling, centrifugal, discards precipitation, collects supernatant;
(4) filtrate of step (3) gained is concentrated, add natural absorptive clarificant, discard precipitation, collect supernatant;
(5) by the supernatant concentration of step (4) gained, dry, pulverize, be distributed into the inner wrapping of 10 grams.
Formula of the present invention forms rationally, and manufacture craft science, carries and instant.There is the effect that regulates vascular endothelium-dependent relaxing factor, contribute to reduce blood fat.Be applicable to simple obesity and hypertension, high fat of blood, hyperglycemia population.
Analysis of drug use
The fruit of Chinese wolfberry is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..
[nature and flavor with return through] are sweet, flat.Return liver, kidney channel.
[effect and application] is nourishing liver and kidney, benefiting shrewd head.Hypopsia, the cataract or glaucoma blurred vision for the treatment of due to asthenia of essence and blood, have a dizzy spell, soreness and weakness of waist and knees, seminal emission lingering diarrhea, deafness, tooth mobility, poliosis, insomnia and dreamful sleep and the deficiency of liver-yin and kidney-yin, hectic fever night sweat, the card such as quench one's thirst.
< < Sheng Nong's herbal classic > > claims the fruit of Chinese wolfberry " to take for a long time hard muscles and bones, make light of one's life by commiting suicide not old, cold-resistant heat ".
< < book on Chinese herbal medicine converges speech > > and praises it " gas can be filled, and blood can be mended, Yang Kesheng, the moon can be grown ".
< < Compendium of Materia Medica > > records: " matrimony vine, kidney-tonifying sperm-generating, nourishing the liver, improving eyesight, hard muscles and bones, goes fatigue, and easily color, bleaches, and improving eyesight is calmed the nerves, and makes us long-lived.”
Modern medicine study confirms: it contains betaine, polysaccharide, crude fat, crude protein, carrotene, vitamin A, vitamin C, Cobastab
1, Cobastab
2and the nutritional labeling such as calcium, phosphorus, iron, zinc, manganese, linoleic acid, modern medicine study proves: the fruit of Chinese wolfberry has facilitation to immunity, has immunoregulation effect simultaneously; Can improve plasma testosterone level, play strong effect; Hematopoiesis function is had to facilitation; Normal healthy people is also had to remarkable effect in increasing leukocyte; Anti-oxidant, anti-ageing, antifatigue, anti-sudden change, antitumor, reducing blood lipid in addition, protect the liver and AFL, hypoglycemic, hypotensive, kidney tonifying, improving eyesight, beauty treatment, brain tonic, toxin expelling, protection reproductive system, 16 functions of Antiradiation injury.
Sealwort is the dry rhizome of liliaceous plant Yunnan sealwort Polygonatum kingianum Coll.et Hemsl., sealwort Polygonatum sibiricum Red. or David's-harp Polygonatum cyrtonema Hua..
[nature and flavor with return through] are sweet, flat.Return spleen, lung, kidney channel.
[effect and application] boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing.Chronic cough, weakness of the spleen and the stomach, fatigue and asthenia, poor appetite, dry food are few, the labor of lung-kidney deficiency is coughed for the few phlegm of dry cough for the treatment of lung gold impairment of both QI and YIN, can delay senility, and improve dizziness, soreness and weakness of waist and knees, poliosis, asthenia of essence and blood, the interior heat disease such as quench one's thirst.
< < Compendium of Materia Medica > >: " mend all void, stop fever and chills, replenishing essence marrow.”
< < Japan hanako materia medica > >: " mend general debility, help muscles and bones, myogenic, cold-resistant heat, beneficial taste, profit cardiopulmonary ".
Modern medicine study confirms: sealwort rhizome contains nicotinic acid, mucilaginous substance, quinones, and containing Siberian solomonseal rhizome polysaccharide first, second, the third, polygonatum rhizome oligosaccharide first, second, the third, polysaccharide first, second, third is combined into by glucose, mannose, galacturonic acid; Compound sugar first, second, third is combined into by glucose and fructose, separately containing 11 seed amino acids such as lysines.Can improve body's immunity and promote the synthetic of DNA, RNA and protein, promote lymphocyte transformation effect; There is significant anti-mycobacterium tuberculosis effect; Multiple pathogenic fungus is had to inhibitory action; Typhoid bacillus, staphylococcus aureus are also had to inhibitory action; Have and increase coronary flow and hypotensive effect, and can reducing blood lipid and alleviate Coronary Artery Atherosclerosis; Blood sugar that adrenaline is caused is too high is remarkable inhibitory action; Suppress in addition adrenocortical effect and delaying senility function; Siberian solomonseal rhizome polysaccharide has Immunestimulatory effect.
Poria cocos is the dry sclerotia of On Polyporaceae Poria cocos Poria cocos (Schw.) Wolf.
[nature and flavor with return through] are sweet, light, flat.The thoughts of returning home, lung, spleen, kidney channel.
[effect and application] clearing damp and promoting diuresis, the peaceful heart of invigorating the spleen.For oedema oliguria, phlegm and retained fluid is dizzy throbs with fear, and insufficiency of the spleen food is few, and have loose bowels in loose stool, confused and worried, palpitation with fear insomnia.
< < Japan hanako materia medica > >: " mend general debility, antiabortive, warm waist knee, happy intelligence development, only forgetful.”
< < medication heart method > >: " sweet with supporing yang, the panacea of dehumidifying also for Poria cocos, the sharp key of light energy.The sweet flat yang-tonifying of taste, beneficial spleen is relieved oedema or abdominal distension through diuresis or purgation, the air guide of promoting the production of body fluid.”
Modern medicine study confirms: Poria cocos energy enhanced machine body immunity function, pachymaran has anti-atrophy of thymus gland and anti-splenomegaly and suppresses the function of tumor growth, pachymaran gavage can strengthen macrophage phagocytosis of mice, increase ANAE positive lymphocyte number, can also make mouse spleen antibody secreting cell count showed increased.Pachymaran also can make the caused big white mouse leucocyte of endoxan reduce and accelerate rise.Carboxymethylpachymaran also have immunological regulation, protecting liver, lowering enzymes, indirectly antiviral, induce and short inducement interferon, alleviate radiation side reaction, induce and urge to induce the multiple physiologically actives such as leukoregulin.
Chinese yam is the dry rhizome of Dioscoreaceae plant Chinese yam Dioscorea opposite Thumb..
[nature and flavor with return through] are sweet, flat.Returning lung, spleen, kidney channel, is the good merchantable brand of flat tonifying lung spleen kidney.
[effect and application] tonifying spleen nourishing the stomach, the beneficial lung that promotes the production of body fluid, the puckery essence of kidney tonifying.Few for insufficiency of the spleen food, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, under band, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) tonifying spleen stomach invigorating.Few for insufficiency of the spleen food, the loose stool of having loose bowels, leukorrhea.
The < < book on Chinese herbal medicine > > that looks for the truth: " enter in drugs for nourishing yin and should give birth to use, entering tonifying spleen lung medicine should use by stir-bake to yellowish." " this genus food, though gas is warm and flat, is the moon of tonifying spleen lung.Can moisten fur, longue meat ... taste is sweet double salty, again can kidney-nourishing reinforcing yin essence.”
< < Compendium of Materia Medica > >: " kidney-nourishing gas, strengthening the spleen and stomach." because it contains more nutritional labeling, easily digest and assimilate again, can be used as food and use for a long time.
< < Sheng Nong's herbal classic > >: " bowl spares, beneficial strength, longue meat ", therefore for chronic disease or weak after being ill, need nutrition adjust to mend and dysfunction of the spleen person is good merchantable brand, as seed of Job's tears yam porridge.
Modern medicine study confirms: the main component of Chinese yam is amylase, can move in stimulating gastrointestinal road, promotes that in intestines, thing is emptying, increases Small Intestinal, contributes to digestion, step-down, hypoglycemic, prevention and cure of cardiovascular disease.The purification starch of Chinese yam can reduce lipid concn, reduces the sugared concentration of sustainer and heart and the concentration of cholesterol simultaneously.Chinese yam is rich in polysaccharide, can stimulate and regulate immune system, can increase blood leucocyte content, strengthen leukocytic phagocytosis, so Chinese yam can be used as the health care medicinal that people increase immunocompetence.In Chinese yam, contain the active ingredients such as protein (comprising 16 seed amino acids that needed by human body is wanted), carbohydrate, vitamins, there is the effect delaying senility preferably, significant prolongation life, often edible Chinese yam, good for health.
Mulberry fruit is the dry fruit ear of moraceae plants mulberry Morus alba L..
[nature and flavor with return through] are sweet, sour, cold.Return liver, kidney channel.
[effect and application] nourishing yin and supplementing blood, promotes the production of body fluid and moisturizes.Be applicable to that dizzy tinnitus, palpitation and insomnia, poliosis, thirsty, the interior heat of Tianjin wound are quenched one's thirst, blood deficiency and constipation, order be dark, tinnitus, scrofula, articular instability.
< < the southern regions of the Yunnan Province book on Chinese herbal medicine > >: " kidney-nourishing is dirty and controlling nocturnal emission with astringent drugs takes black invention order for a long time.”
< < is with ceasing living in seclusion recipe > >: " wines used as antirheumatic, walks with vigorous strides to carry out, and ceases empty wind, the clear fire of deficiency type for nourish liver and kidney, enrich blood.”
< < Bencao Shiyi > >: " sharp the five internal organs joint, logical vim and vigour.Clothes are not hungry for a long time, and spirit sedation, makes us clever, bleaches not old.”
Modern medicine study confirms: mulberry fruit is sugary, tannic acid, malic acid and Cobastab
1, B
2, C and carrotene.The aliphatic acid of Fructus Mori oil is mainly comprised of linoleic acid and stearic acid, oleic acid etc.Be improved skin (comprising scalp) blood supply, nutrition skin, makes the effects such as the delicate and Wu Fa of skin, and can delay senility, and is be healthy and strong U.S. face, antidotal good fruit and good medicine.Normal food mulberry fruit can improving eyesight, the symptom that relieving eye strain is dry and astringent.Mulberry fruit has immunologic enhancement, and spleen is had to effect of gain, and to hemolytic, reaction has humidification, can prevent human body artery sclerosis, bone arthrosclerosis, enhances metabolism.It can promote the growth of erythrocyte, prevents that leucocyte from reducing, and the illnesss such as treatment diabetes, anaemia, hypertension, high fat of blood, coronary heart disease, neurasthenia are had to auxiliary effect.Proper amount of edible can promote gastric secretion, stimulates enterocinesia and removes scorching.
Hawthorn is the dry mature fruit of rosaceous plant large-fruited Chinese hawthorn Crataegus pinnatifida Bge.var.major N.E.Br. or hawthorn Crataegus pinnatifida Bge..
[nature and flavor with return through] acid, sweet, tepor.Return spleen, stomach, Liver Channel.
[effect and application] food digesting stomach fortifying, the promoting the circulation of qi stasis of blood of faling apart, changes turbid lipopenicillinase.For carnivorous stagnant, gastral cavilty turgor, rushes down dysentery stomachache, and hemostasis is through closing, postpartum stasis blocking, trusted subordinate's shouting pain, chest impediment and cardialgia, hernia pain, hyperlipidemia.
The < < book on Chinese herbal medicine > > that looks for the truth: hawthorn, so-called invigorating the spleen person, because its spleen has dyspepsia, with the salty taste of this acid, think and wear down, in order to do food row, phlegm disappears, broken and the letting out of gas, meaning for strong, only belong to being good for for the treatment of for relieving indigestion and constipation.
< < Bencao Jingshu > >: hawthorn, strengthening the spleen and stomach, row knot gas, hemostasis disappears.
< < explaining abstruseness of the canon of materia medica > >: hawthorn, taste neutralization, the grease that disappears is long-pending.
< < day is with herbal > >: helping digestion is long-pending, row knot gas, the wide diaphragm of stomach invigorating, the blood mass at the right hypochondrium that disappears piece.
Modern medicine study confirms: the main component of hawthorn is Flavonoid substances, and cardiovascular system is had to obvious pharmacological action, and wherein Vitexin, is the medicine that a kind of antitumaous effect is stronger.The composition of another kind of outbalance is triterpene substance, has cardiac stimulant, increases coronary blood flow, improves the important function such as blood circulation.In addition, in hawthorn, contain organic acid as chlorogenic acid, caffeic acid and tannin, the acid anhydride of tanning, epicatechol, choline, acetylcholine, cupreol, carrotene and vitamin C etc., there is the effects such as reducing blood lipid, blood pressure, cardiac stimulant and arrhythmia.Haw thorn extract all has certain inhibitory action to cancer cell tumor growth, propagation and infiltration metastasis.
Cassia seed is the dry mature seed of legume Cassia tora Cassia obtusifolia L. or little Cassia tora Cassia tora L..
[nature and flavor with return through] are sweet, bitter, salty, are slightly cold.Return liver, large intestine channel.
[effect and application] removing heat to brighten vision, relaxes bowel.For the puckery pain of hot eyes, the many tear of photophobia, has a headache dizzy, and order is secretly not clear, constipation.
< < property of medicine opinion > >: sharp the five internal organs, except liver man heat.
< < Japan hanako materia medica > >: help irritability, beneficial smart water.
The just > > of < < book on Chinese herbal medicine: cassia seed improving eyesight is to grow liver and kidney benefiting, take the latent tonifying yin in town as justice, is the normal treatment of reinforcing.
Modern medicine study confirms: Cassia tora fresh seeds is containing Chrysophanol, archen, aloe-emodin, Rhein, emodin monoglucoside, emodin anthrone, Physcion, obtusin, aurantio-obtusin and rubrofusarin, Cassia tora pine, toralactone, chrysophanic acid-9-anthrone, also containing vitamin A.Pharmacological research shows that cassia seed has and reduces blood pressure and the effect of serum total cholesterol and triglycerides.The extract of cassia seed has obvious inhibitory action to pathogenic microorganism.
Lotus leaf is the dry leaf of nymphaeaceae plant lotus Nelumbo nucifera Gaertn..
[nature and flavor with return through] are bitter, flat.Return liver, spleen, stomach warp.
[effect and application] clearing away summer-heat and eliminating dampness, sending up the lucid yang, cooling blood and hemostasis.For hot summer weather polydipsia, summer heat damp diarrhea, splenasthenic diarrhea, blood-head is told nosebleed, the uterine bleeding of having blood in stool.
< < Compendium of Materia Medica > >: " lotus leaf takes it, makes us thin bad ", " hair tonic vigour, benefit helps taste, and puckery essence is turbid, scattered silt blood, detumescence pain, sends out variola ".
Modern medicine study confirms: in lotus leaf, contain multiple alkaloid: Nuciferine, N-nornuciferine, O-remove first Nuciferine, reticuline, spot Asia papaverine, Armenia's papaverine, N-methyl coclaurine, N-methyl isococlaurine, Pronuciferine, liriodendrin, dehydronuciferine; Flavone compound: Quercetin and isoquercitin; And the organic acid composition such as vitamin C, citric acid, tartaric acid, malic acid, oxalic acid, butanedioic acid.Wherein flavones and alkaloids composition have the function that regulates blood fat, and effect feature is mainly the metabolism that promotes cholesterol.
Chrysanthemum is the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..
[proterties with return through] is sweet, bitter, is slightly cold.Return lung, Liver Channel.
[effect and application] the wind heat-clearing of faling apart, flat liver improving eyesight, clearing heat and detoxicating.For anemopyretic cold, have a headache dizzy, red eye, swell pain, eyes is dim-sighted, sore and toxic.
< < Sheng Nong's herbal classic > >: bitter is flat.Main all wind, dizzy, swell and ache, order wish is de-, lacrimation; The dead flesh of skin, dislikes rheumatism numbness.Take for a long time sharp vim and vigour, make light of one's life by commiting suicide resistance to old, prolong life.
< < Amplification on Materia Medica addendum > >: chrysanthemum, can tonifying yin.
The newly organized > > of < < book on Chinese herbal medicine: Flos Chrysanthemi, smell is gently clear, and merit is also very slow, and clothes beginning effect, can not blame with nearly merit for a long time.Lid Yang Mingneire, with Flos Chrysanthemi to, two liang, the fire in can flat stomach, and the gas not injuring one's stomach is also.
Modern medicine study confirms: chrysanthemum has prevention and cure of cardiovascular disease, antibacterial, anticancer, the anti-ageing effect of waiting for a long time.Flavone compound is as the medicinal important activity position of chrysanthemum, mainly contain: apiolin, api-genin-7-O-β-D-glucoside, apiolin-7-O-rhamnoside, apiolin-7-O-galactopyranose, acacetin, acacetin7OβDglucoside, acacetin-7-O-galactopyranose, robinin, acacetin-7-O-(6 "-O-acetyl)-β-D-Glucose glycosides, diosmetin, diosmetin-7-O-β-D-Glucose glycosides, Luteolin, Luteolin-7-O-glucoside, Quercetin, Quercetin-3-O-galactoside, quercitin, 5-hydroxyl-3 ', 4 ', 6, 7-tetramethoxy flavones, kaempferol, baicalein, gossypethyl pentamethylether, eupatilin, aurantiamarin etc.Angiocardiopathy, cancer, disease of immune system are had to significant pharmacological action.Volatile oil is the material base of chrysanthemum antibacterial action, and camphor wherein, borneol are the main component of its performance antibacterial action, especially the most obvious to the bacteriostasis of staphylococcus aureus.The beta-elemene containing in volatile oil has the pharmacological actions widely such as broad-spectrum anti-tumor.
Radish seed is the dry mature seed of crucifer radish Raphanus sativus L..
[nature and flavor with return through] are pungent, sweet, flat.Return lung, spleen, stomach warp.
[effect and the application] de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, constipation, the stagnant dysentery of rushing down, phlegm heap soil or fertilizer over and around the roots is breathed with cough.
< < Records of Tradition Chinese and Western Medicine in Combination > >: " radish seed, no matter or raw or fry, all can regulating QI to remove the stagnation, dissipate-swelling is except full, the product of this being gas, the product of non-relieving stagnant Qi.”
< < the southern regions of the Yunnan Province book on Chinese herbal medicine > >: " expansion that disappears, dissolving phlegm saliva, the place food that disappears, the area that disappears is stagnant.”
< < Compendium of Materia Medica > >: " merit of radish seed is longer than sharp gas.Raw can liter, ripe can falling, rises and tells wind phlegm, and dispersing wind and cold is sent out sore rash; Fall and determine asthma due to excessive phlegm cough, heavy after tune diarrhea, only interior pain, is all the effect of sharp gas.”
Modern medicine study confirms: the main fatty acids of radish seed, volatile oil.In volatile oil, contain methyl mercaptan, alpha-beta-hexenoic aldehyde and β-γ-hexenol.During fat is grease proofing, contain erucic acid, linoleic acid, leukotrienes, sinapic acid, glyceride, also containing antibacterial material raphanin, positive melissane, cupreol, clionasterol, 18 carbonic acid, phytolaccagenic acid, sinapine sulfate of ammoniac salt, and carbohydrate and several amino acids, vitamin etc.
Function assessment is evaluated
1, experimental animal
50 of clean level Wistar kind rats, male, body weight 130~160g.
Basal feed formula (%) is as follows: bean powder 20, pearling cone meal 20, corn flour 16, wheat bran 16, cabbage 10, fish meal 10, bone meal 5, salt 2, yeast 1.
High fat nutrient fodder formula is as follows: in every 100g basal feed, add milk powder 10g, lard 10g, 1 piece, egg, 10 of cleum jecoris piscis concentratums and fresh moyashi 250g.
2, test method
Be divided at random basic, normal, high dosage group, Normal group, obese model group, every group of 10 animals.Three every of dosage groups are fed to measure and are respectively 2.5g/kg, 5g/kg, 10g/kg, and every day is gavage regularly, and gavage amount is 0.2ml/10g, and Normal group and obese model group rat give the physiological saline of equivalent, and gavage is 35 days continuously.Except Normal group gives basal feed, all the other each groups all give high fat nutrient fodder and feed.
(1) body weight and fat are heavy
After off-test, weigh, cut open the belly and get body fat (testis and perinephric fat pad) and be placed on filter paper and suck tissue fluid, weigh, calculate fat/body ratio.
(2) blood fat
Abdominal aortic blood after off-test, measures T-CHOL (TC), triglycerides (TG), three indexs of HDL (HDL-C) after separation of serum.
3, result of the test
(1) impact on body weight
From table 1, test last obese model group rat body weight and increase higher than Normal group, learn by statistics check, difference has conspicuousness (p < 0.05), and the fat model manufacturing success of animal is described.And feed each dosage group rat body weight raise high fat nutrient fodder simultaneously, increase all lower than obese model group, learn by statistics check, middle and high dosage group rat body weight increases and obese model group comparing difference has conspicuousness or highly significant (p < 0.05 or P < 0.01)
Note: with Normal group comparison: #P < 0.05; With obese model group comparison: * P < 0.05, * * P < 0.01.
(2) impact on body fat
From table 2, test the body fat weight in wet base of last obese model treated animal and fat/body than all higher than Normal group, learn by statistics check, difference has highly significant (p < 0.01), illustrate that the fat model manufacturing of animal is successful.Feed simultaneously and raise each dosage treated animal body fat weight in wet base of high fat nutrient fodder and fat/body than all lower than obese model group, learn by statistics check, the body fat weight in wet base of middle and high dosage treated animal and fat/body ratio and the comparison of obese model group, difference has conspicuousness or highly significant (p < 0.05 or P < 0.01).
(3) impact on serum TC, TG, HDL-C
From table 3, obese model group Serum TC and TG content, all higher than Normal group, are learned check by statistics, and difference has highly significant (p < 0.05), and the fat model manufacturing success of animal is described.High, middle dosage group Serum TC, TG content and obese model group relatively have obvious reduction, and difference all has conspicuousness (p < 0.05); High, medium and low dosage group rat blood serum HDL-C value and Normal group and the comparison of obese model group, there are no significant for difference (p > 0.05).
Note: with Normal group comparison: ##P < 0.01; With obese model group comparison: * P < 0.05, * * P < 0.01.
Note: with Normal group comparison: #P < 0.05; With obese model group comparison: * P < 0.05.
4, conclusion (of pressure testing)
This result of the test shows, product of the present invention can prevent the increase of feeding high fat nutrient fodder rat body weight and body fat content effectively, prevents the rising of T-CHOL and triglyceride levels in its serum.This very likely, obesity on the high side to grease in society people diet and hyperlipidemia population to be the situation that rejuvenation rises helpful.
The specific embodiment
The preparation of embodiment 1 extract and product
By optimum weight proportioning, take 1000 parts of the fruits of Chinese wolfberry, 1000 parts of sealworts, 1000 parts, Poria cocos, 1500 parts of Chinese yams, 1000 parts, mulberry fruit, 1000 parts of hawthorn, 1200 parts of cassia seeds, 600 parts, lotus leaf, 700 parts of chrysanthemums, 1000 parts of radish seeds.Adding 10 times of amount deionization poach carries 2 times, each 2 hours, leach cooking liquid filtration, centrifugal (3000 revs/min) 30 minutes, get supernatant, be concentrated into liquid than 1: 2 (60 ℃), after add natural absorptive clarificant, then centrifugal (3000 revs/min) 30 minutes, get supernatant and continue be concentrated into relative density>=1.27gml
-1after, belt drying, is ground into fine powder, is distributed into the inner wrapping of 10 grams of left and right.
Embodiment 2 product treatment simple obesity
Experimenter Wang, man, 40 years old, height 170cm, body weight 87kg, BMI=30.1.Take product of the present invention 60 days, during diet with daily consistent, motion conditions is with daily consistent.After test, lose weight 6.8%, physique content reduces 4.0%, and its deltoid muscle subcutaneous fat thickness and hip circumference all decrease.
During test-meal, experimenter does not observe obvious allergy and other bad reactions, and spirit, sleep, diet, stool and urine are in order.Edible tested material is after 60 days, and experimenter's blood pressure, heart rate, routine blood test, urine just routine and biochemical indicator are showed no obvious abnormalities variation, and the inspections such as electrocardiogram, Abdominal B type ultrasonography, Chest X-rays are showed no extremely, point out this given the test agent to body health without obvious damage.
Claims (5)
1. a health preserving health-care food formula that contributes to lowering blood-fat and reducing weight, is characterized in that raw material used and parts by weight thereof: fruit of Chinese wolfberry 600-1400 part, sealwort 600-1500 part, Poria cocos 600-1500 part, Chinese yam 1000-2000 part, mulberry fruit 800-1300 part, hawthorn 800-1200 part, cassia seed 900-1500 part, lotus leaf 300-1000 part, chrysanthemum 500-1000 part, radish seed 500-1200 part.
2. a kind of health preserving health-care food formula that contributes to lowering blood-fat and reducing weight according to claim 1, is characterized in that raw material used and parts by weight thereof: fruit of Chinese wolfberry 700-1300 part, sealwort 700-1400 part, Poria cocos 700-1400 part, Chinese yam 1200-1800 part, mulberry fruit 900-1200 part, hawthorn 900-1100 part, cassia seed 1000-1400 part, lotus leaf 400-900 part, chrysanthemum 600-900 part, radish seed 600-1100 part.
3. a kind of health preserving health-care food formula that contributes to lowering blood-fat and reducing weight according to claim 1, is characterized in that raw material used and parts by weight thereof: 1000 parts of the fruits of Chinese wolfberry, 1000 parts of sealworts, 1000 parts, Poria cocos, 1500 parts of Chinese yams, 1000 parts, mulberry fruit, 1000 parts of hawthorn, 1200 parts of cassia seeds, 600 parts, lotus leaf, 700 parts of chrysanthemums, 1000 parts of radish seeds.
4. according to a kind of preparation method who contributes to the health preserving health-care food of lowering blood-fat and reducing weight described in claim 1,2 or 3, it is characterized in that preparation process carries out according to the following steps:
(1) each medicinal material in formula is placed in to boil carries pot, infiltrate 30 minutes, then add the deionized water of 10 times of amounts, soaking at room temperature 2 hours; Then be heated to boiling, boil and extract 2 hours, the water outlet extract that inclines, filters;
(2) again add the deionized water of 10 times of amounts of medicinal material, boil and extract 2 hours, the water outlet extract that inclines, filters;
(3) combining step (1), (2) gained filtrate, cooling, centrifugal, discards precipitation, collects supernatant;
(4) filtrate of step (3) gained is concentrated, add natural absorptive clarificant, discard precipitation, collect supernatant;
(5) by the supernatant concentration of step (4) gained, dry, pulverize, be distributed into the inner wrapping of 10 grams.
5. according to a kind of health preserving health-care food that contributes to lowering blood-fat and reducing weight described in claim 1,2 or 3, it is characterized in that: the present invention contributes to reduce blood fat and reduces body fat, is applicable to simple obesity and hypertension, high fat of blood, hyperglycemia population.
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