CN103417837B

CN103417837B - Medlar health preserving cream of a kind of medicine-food two-purpose and preparation method thereof

Info

Publication number: CN103417837B
Application number: CN201310374038.0A
Authority: CN
Inventors: 蒋正国; 张万昌
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-08-26
Filing date: 2013-08-26
Publication date: 2016-03-30
Anticipated expiration: 2033-08-26
Also published as: CN103417837A

Abstract

The invention discloses a kind of medlar health preserving cream of medicine-food two-purpose, comprise following raw material, its composition and mass fraction be, Fructus Lycii 8 ~ 20 parts, Rhizoma Polygonati 0.5 ~ 6 part, Radix Panacis Quinquefolii 0.5 ~ 8 part.Also disclose the method for this medlar health preserving cream of preparation, comprise the steps, starting material with water is cleaned five times by (1), and then soaks 2 ~ 4h; (2) Fructus Lycii handled well through upper step inserts frying pan, and Rhizoma Polygonati, Radix Panacis Quinquefolii are chopped into lamellar and insert frying pan more respectively and decoct; (3) continue to decoct after above-mentioned medicine juice being done filtration treatment, constantly stir concentrated; (4) by the medical filtration that upper step process obtains, then pour frying pan continuation heating into, and constantly stir, be stirred to and mention stirring rod medicine juice extension flag, stop heating both to obtain soft extract.Medlar health preserving cream nature and flavor of the present invention are gentle, do not have the generation of side effect such as getting angry while playing the effects such as resisting fatigue to human body, and the medlar health preserving cream pesticide residues prepared through the method are low, heavy metal is low, and nutritional labeling is high.

Description

Medlar health preserving cream of a kind of medicine-food two-purpose and preparation method thereof

Technical field

The present invention relates to the product technical field of natural components medicine-food two-purpose, specifically a kind of medlar health preserving cream and preparation method thereof of medicine-food two-purpose.

Background technology

Fructus Lycii, the flat temperature partially of sweet in the mouth, enters Liver and kidney warp.There is nourishing the liver and kidney, nourish blood and mend essence, the merit of improving eyesight lung moistening, having a dizzy spell of kind treating the liver kidney deficiency, soreness of the waist and knees, visual deterioration, pass out semen and quench one's thirst, the diseases such as cough due to consumptive disease, prior art is except regarding Fructus Lycii as medical material simply, what also have makes food or health product Fructus Lycii, such as publication number is a kind of Nourishing wolfberry fruit ointment of CN1000341541C, its Nourishing wolfberry fruit ointment forms: Fructus Lycii 500g, Radix Angelicae Sinensis 50g, the sub-3g of Cornu Cervi disk stripping, Mel 500g makes, but this Nourishing wolfberry fruit ointment, not all crowd all edibles, because the reason of body void is different, some people there will be the symptom of getting angry after edible, make in body more scorching, do not reach health-care effect, and existing medlar health preserving cream as health product time, in order to the multiplex Colla Corii Asini of seasoning, cream received by Colla cornus cervi or Mel, diabetes patient and people with hyperlipidemia are not suitable for even avoiding, edible crowd's scope is wideless, tonic effect is waited to improve.

Summary of the invention

In order to solve the defect that above-mentioned existing Fructus Lycii medicine or food consumption crowd scope are wide, tonic effect is to be improved, medlar health preserving cream that the invention discloses a kind of medicine-food two-purpose and preparation method thereof, hyperlipidemia, diabetes patient also can be used, and realize auxiliary antilipemic, blood sugar lowering, improve the object of fatigue state.

For achieving the above object, the technical scheme adopted is, the medlar health preserving cream of a kind of medicine-food two-purpose that the present invention outputs, comprise following raw material, its composition and mass fraction are, Fructus Lycii 8 ~ 20 parts, Rhizoma Polygonati 0.5 ~ 6 part, Radix Panacis Quinquefolii 0.5 ~ 8 part, the present invention is with Fructus Lycii, Rhizoma Polygonati, Radix Panacis Quinquefolii is Main Ingredients and Appearance, take merely Fructus Lycii or medlar health preserving cream, because human body constitution natural endowment has biased, the crowd of about 1/3rd has " getting angry " symptom, as toothache, gingival swelling and pain is hemorrhage, epistaxis, aphtha of the mouth and tongue, dryness of the mouth and throat, the symptoms such as constipation, so the present invention by three kinds of compositions through scientific compatibility, the nutrition of absorption of human body Fructus Lycii is not only made to have effect of health care, there will not be side effect such as getting angry simultaneously, and this medlar health preserving cream does not separately add saccharide, the materials such as colloid, make hyperglycemia, crowd's also edible of hyperlipidemia, expand applicable crowd.

Fructus Lycii, the flat temperature partially of sweet in the mouth, enters Liver and kidney warp.There is nourishing the liver and kidney, nourish blood and mend the merit of essence, improving eyesight lung moistening, having a dizzy spell of kind treating the liver kidney deficiency, soreness of the waist and knees, visual deterioration, pass out semen and quench one's thirst, the disease such as cough due to consumptive disease.Fructus Lycii originates in the ground such as Ningxia, Gansu, Inner Mongol, Qinghai, and lycium barbarum can be used as medicine, and rather producing Fructus Lycii is wherein genuine traditional Chinese medicine material, have the laudatory title of " in peaceful Fructus Lycii unsurpassed ".

Compendium of Material Medica carries Fructus Lycii " nourishing kidney, lung moistening, improving eyesight, take hard muscles and bones, not old, resistance to cold and summer-heat of making light of one's life by commiting suicide, benefit vital essence various symptoms and signs of deficiency for a long time, beneficial color, and improving eyesight is calmed the nerves ".Materia Medica of Decoction: " master is taking fluids profusely yearningly, during nephropathy disappears." Collective Notes to the Canon of Materia medica: effects such as " nourishing the essence and strengthening QI, prosperous and powerful vaginas ", modern pharmacology Fructus Lycii extractum has blood sugar lowering, effect for reducing blood fat.Lycium barbarum polysaccharide has enhancing immunity, antitumor action.Decoct and alcohol extract have blood pressure lowering, defying age, anti-hypoxia, resisting fatigue, antioxidation, radiation resistance; protect hepatocyte in addition; promote hepatocellular new life; recover liver function, all have good preventive and therapeutic effect to diseases such as chronic hepatitis, central serous chorioretinopathy, pulmonary tuberculosis, diabetes, neurasthenias.

Though Fructus Lycii does not have the fame and prestige of Radix Ginseng, Cordyceps honorable, no matter men and women, old and young, high and low rich or poor, the person of knowledge is many, and the person of use is many, is common people's good medicine of being bestowed by heaven simply.Fructus Lycii medicine food is all good, except being used as medicine, also has multiple eating method.Wherein soft extract, boiled concentrated by more than ten hours, human body the most easily absorbs, and utilization rate is the highest, and tonic effect is best.

Rhizoma Polygonati is also a kind of tonification good merchantable brand of medicine-food two-purpose, sweet flat moist, enters spleen, lung, kidney channel.Can nourishing kidney-yin, lung moistening dry, again can tonifying spleen-yin, strengthening the spleen gas.Control deficiency of YIN cough caused by dryness, chronic cough chronic cough, use can nourishing kidney-yin, the dry and cough-relieving of lung moistening; Control the disease of weakness of the spleen and stomach, use can QI invigorating and tonifying YIN; Control deficiency of kidney-essence, the card such as soreness of the waist and knees, dizziness.Also deficiency of kidney-essence can be controlled, the diabete of YIN-fluid being insufficient.Compendium of Material Medica carries Rhizoma Polygonati to be had " mending all void, only cold and heat, replenishing essence marrow ", " Mingyi Bielu ": " main invigorating the spleen and replenishing QI, except rheumatism, settling five organs.Deficient clothes make light of one's life by commiting suicide prolong life not hungry ".Modern study, Rhizoma Polygonati is containing polygonatum polysaccharide, oligosaccharide, phlegmatic temperament and several amino acids.Polysaccharide can strengthen immunologic function and promote the synthesis of DNA, RNA and protein.Decoct has blood sugar lowering, blood fat reducing, increase coronary flow, heart tonifying, resists myocardial ischemia, resisting fatigue, antioxidation, defying age, antibacterium and fungus, antivirus action.

Radix Panacis Quinquefolii is the rare medicinal herbs of QI invigorating tonifying YIN, and it is cold in nature, sweet and micro-hardship.GUIXIN lung stomach warp.Merit arrogates to oneself boosting qi and nourishing yin, relieves inflammation or internal heat and promotes the production of body fluid, for controlling the good merchantable brand of deficiency of both vital energy and Yin and fire Sheng." Records of Tradition Chinese and Western Medicine in Combination " is said: " Radix Panacis Quinquefolii is cool in nature and mend, all wish Radix Ginsengs and by the temperature compensation person of the Radix Ginseng, all can this generation it." " Bencao Congxin " carry that " relieving restlessness is tired for tonifying the lung pathogenic fire reducing, born fluid, empty and have fiery person suitable." " book on Chinese herbal medicine is new again ": " control lung-fire prosperous, cough with copious phlegm, the deficiency of vital energy breathes out to breathe heavily, impairment caused by overstrain of losing blood, and controlling nocturnal emission with astringent drugs is calmed the nerves ".Modern study Radix Panacis Quinquefolii containing ginsenoside Rg 17 kinds of volatile oil such as saponin, 10-Pinen-3-ol such as Rb, organic acid, sterol carbene class, aminoacid, protein and polysaccharide etc.Wherein Radix Panacis Quinquefolii saponin and polysaccharide etc. are its principle active component.Radix Panacis Quinquefolii has calmness, resists myocardial ischemia, heart tonifying, shock, diuresis, hepatoprotective, anti-hypoxia, fatigue-resisting function.

This medlar health preserving cream also comprise sky essence grass 0.5 ~ 5 part, Cortex Lycii 1 ~ 10 part, Chinese wolfberry carpopodium 0.5 ~ 8 part, in 0.5 ~ 5 part, Radix Glycyrrhizae any one, two or more mixing, above-mentioned number is mass fraction, these accessory ingredients are all edible compositions well known in the art, accessory ingredients does not use the auxiliary additive of saccharide, Mel, glue and so on, so be also edible to the crowd such as diabetes patient, hypertension, formula pure natural, receive cream without glue or saccharide, achieve the medlar health preserving cream of real edible safety.

Cortex Lycii is lycii radicis,cortex, and property is sweet cold, returns lung, liver, kidney channel, has clearing away deficiency-heat, clearing away heat and cooling blood, the merit of lung heat clearing pathogenic fire reducing.Clinical being commonly used to treats fever due to yin deficiency, especially arrogates to oneself and controls asthenia hectic fever due to YIN-deficiency, vexed night sweat.The haematemesis of bleeding due to blood-heat, epistaxis, all cards of hematuria can be controlled again.Also can lung heat clearing fire and control cough due to lung-heat." Treatise on Dietetic Therapy ": " heat of boning is quenched one's thirst." " pearl sac ": " separate hectic fever due to YIN-deficiency flesh heat, quench one's thirst, rheumatalgia, hard muscles and bones, removing heat from blood." modern study Cortex Lycii is containing cinnamic acid, betanin, bitter Ke's alkali A, Fructus Lycii element A, Fructus Lycii element B, linoleic acid, linolenic acid and phenols etc.This product decoct can suppress Bacillus typhi, paratyphoid bacillus A, bacterium flexneri.Water extract, ethanol extraction have stronger refrigeration function, also have certain hypotensive effect, Cortex Lycii are added in composition of the present invention, make medlar health preserving cream of the present invention have effect of secondary buck, and can restrain the inclined using warming therapy of Fructus Lycii.

It essence grass, be again Fructus Lycii Seedling, have another name called Fructus Lycii head, Herba mesonae chinensis, be the young stem and leaf of Fructus Lycii, hardship, Gan Erliang.Enter the heart, lung, spleen, kidney four warp.There is the liver and the kidney tonifying, promoting the production of body fluid to quench thirst, expelling wind and removing dampness, effect of blood circulation promoting and blood stasis dispelling.Cure mainly deficient fever, excessive thirst, the confused disease such as pain, nyctalopia of hiding from view, bleeding not during menses, hot carbuncle toxin of conjunctival congestion.Its " gas can be made to fill, and blood can be mended, Yang Kesheng, and sun can be grown, and rheumatism can be gone, and has perfect here wonderful " is praised in " book on Chinese herbal medicine converge with speech "." Japan hanako materia medica " thinks its " relieving restlessness Fructus Alpiniae Oxyphyllae, mend wind, the pyretic toxicity that disappears, loose skin ulcer between five kinds of strain and seven kinds of impairment, high aspiration gas, peeling skin joint swell "." Fructus Lycii head ... hungry people is satiated with food as delicacy " is claimed in " the melon menu " of king's huge rock.The main aminoacid containing tens kinds of needed by human such as betanin, carotene, ascorbic acid, linoleic acid, aspartic acid, glutamic acid, methionine, taurines in medlar bud, and be rich in the trace element of the multiple needed by human such as calcium Ca, ferrum Fe, zinc Zn, selenium Se, vitamin B1, vitamin B2, vitamin C.Fructus Lycii Seedling is the good merchantable brand of medicine-food two-purpose.Sky essence grass is added to medlar health preserving cream of the present invention and has the effect increasing body immunity.

Chinese wolfberry carpopodium is the coupling part between FRUCTUS LYCII and branch, bitter in the mouth, property is put down, have a surname to send out, rise, walk table, rash, acne removing, skin care, white skin, improving eyesight, control effect of five kinds of strain and seven kinds of impairment, Chinese wolfberry carpopodium is added among composition by the present invention auxiliary hyperglycemic, blood pressure reduction effect.

Radix Glycyrrhizae, treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Raw by pathogenic fire purging heat, ripe use is fallen apart exterior cold, and go pharyngalgia, except pathogenic heat, slow healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening, is added to Radix Glycyrrhizae in composition of the present invention and assists medlar health preserving cream to overcome the defect of easily getting angry.

The invention also discloses the method preparing medicine-food two-purpose medlar health preserving cream, comprise the steps, (1) Fructus Lycii of 8 ~ 20 parts, the Rhizoma Polygonati of 0.5 ~ 6 part, the Radix Panacis Quinquefolii water of 0.5 ~ 8 part are cleaned five times, and then soaks 2 ~ 4h, above-mentioned number is mass fraction; Fully medical material is cleaned, then be soaked in water impurity, residual pesticide etc. removed;

(2) Fructus Lycii handled well through upper step inserts frying pan, Rhizoma Polygonati, Radix Panacis Quinquefolii are chopped into lamellar and insert frying pan respectively again, in each frying pan discharge water and be 10:1 with the ratio of quality and the number of copies of medical material, medicine juice is taken out after each decoction 2h, adding water again makes the quality proportioning of water and medical material constant, steaming and decocting three times, finally mixes all medicine juice, is placed in container and places 6h altogether; Fructus Lycii, Rhizoma Polygonati, Radix Panacis Quinquefolii need a large amount of water when decocting, and place 6h, just in time can make the medicinal residues precipitation remained, well medicine juice and medicinal residues juice be separated;

(3) be again placed in frying pan after above-mentioned medicine juice being done filtration treatment, after being heated to boiling, using slow fire instead, constantly stir concentrated medicament; Carry out further filtering and medicine juice further can being purified to medicine juice, then excessive moisture is evaporated, make sticky being convenient to of medicinal liquid follow-uply obtain paste;

(4) by the medical filtration that upper step process obtains, then pour the heating of frying pan maintenance slow fire into, and constantly stir, be stirred to and mention stirring rod medicine juice extension flag, stop heating both to obtain paste.Do not use colloid, Mel etc. can obtain medlar health preserving cream before hanging flag, expand use crowd.

When the raw material of medlar health preserving cream also comprises sky essence grass, Cortex Lycii, Chinese wolfberry carpopodium, Radix Glycyrrhizae, the concrete operations of described method step (1), (2) are, (1) Fructus Lycii of 8 ~ 20 parts, the Rhizoma Polygonati of 0.5 ~ 6 part, the Radix Panacis Quinquefolii of 0.5 ~ 8 part, the sky essence grass of 0.5 ~ 5 part, the Cortex Lycii of 1 ~ 10 part, 0.5 ~ 8 part of Chinese wolfberry carpopodium, the Radix Glycyrrhizae use water of 0.5 ~ 5 part are cleaned five times, and then soaking 2 ~ 4h, above-mentioned number is mass fraction; When adding other composition again, the step of cleaning is identical.

(2) Fructus Lycii, Rhizoma Polygonati, Radix Panacis Quinquefolii is 1. decocted: the Fructus Lycii handled well through upper step is inserted frying pan, Rhizoma Polygonati, Radix Panacis Quinquefolii are chopped into lamellar and insert frying pan respectively again, in each frying pan discharge water and be 10:1 with the ratio of quality and the number of copies of medical material, medicine juice is taken out after each decoction 2h, adding water again makes the quality proportioning of water and medical material constant, decoct three times altogether, finally all medicine juice are mixed;

2. Cortex Lycii, sky essence grass, Chinese wolfberry carpopodium, Radix Glycyrrhizae is decocted: the smart grass in the Cortex Lycii handled well through (1), sky, Chinese wolfberry carpopodium, Radix Glycyrrhizae are inserted in frying pan respectively, the water added in each frying pan all exceeds medical material 3 ~ 5cm, first soak 6 ~ 8 hours, then decoct 2 times, each elder generation boils with high heat, with slow fire boiling 2 hours after boiling, filtration obtains medicine juice, before second time decocts, wanting supplementing water to ensure, it is highly constant, filter the medicinal liquid obtained after twice decoction to be incorporated in above-mentioned Fructus Lycii admixing medical solutions, be placed in container and place 6h.The Cortex Lycii etc. added is mostly root bark or lobate, and first soak and medical material is soaked, its effective ingredient is easily fried, then decocts and just can obtain the beneficial in composition in 4 hours.

After described step (4) obtains medlar health preserving cream, spend when also not leaving while hot, pour into fast and to have cleaned and in the container of sterilizing, Temperature fall at ambient temperature, until medlar health preserving cream temperature is cool to room temperature, row capping is preserved again, the temperature of preserving is 2 ~ 8 DEG C, a year and a half can be preserved at most, this is the condition that population family refrigerator can both obtain, storage conditions does not need the environment of special experimental laboratory, but because not adding other material any in medlar health preserving cream, preserving at most can not more than 1 year half.

In sum, beneficial effect of the present invention, one, by scientific and reasonable formula, solve and take merely Fructus Lycii or take single medlar health preserving cream, some crowd is not suitable for, and easily occurs the side effect of " getting angry " symptom.

Its two, processing technology unlike the prior art, has been accomplished the composition of pure natural, has not been added colloid, Mel, also do not add antiseptic, edible safety, even if the personages such as diabetes, hyperlipidemia, hypertension also can take, edible crowd is extensive.

Its three, by the interpolation of other auxiliary ingredients, make this medlar health preserving cream blood fat reducing, blood pressure lowering, hypoglycemic activity strengthen, improve the effect of immunity, antifatigue effect also strengthens simultaneously.

Its four, medlar health preserving paste formulation of the present invention is all the composition of medicine-food two-purpose, both can regard the adjuvant drug of hyperlipidemia, diabetes, also can as resisting fatigue, improve immunity health food eat.

Detailed description of the invention

Content of the present invention is further illustrated below in conjunction with concrete case of implementing.

Embodiment one: the medlar health preserving cream of a kind of medicine-food two-purpose that the present invention develops, comprises following raw material, its composition and mass fraction be, Fructus Lycii 10 parts, Rhizoma Polygonati 1 part, Radix Panacis Quinquefolii 1 part.

Prepare the method for above-mentioned medicine-food two-purpose medlar health preserving cream, comprise the steps, the Fructus Lycii of 10 parts, the Rhizoma Polygonati of 1 part, the Radix Panacis Quinquefolii water of 1 part are cleaned five times, and then soak 2 ~ 4h by (1), and above-mentioned number is mass fraction;

(2) Fructus Lycii handled well through upper step inserts frying pan, Rhizoma Polygonati, Radix Panacis Quinquefolii are chopped into lamellar and insert frying pan respectively again, in each frying pan discharge water and be 10:1 with the ratio of quality and the number of copies of medical material, medicine juice is taken out after each decoction 2h, adding water again makes the quality proportioning of water and medical material constant, decoct three times altogether, finally all medicine juice are mixed, be placed in container and place 6h;

(3) be again placed in frying pan after above-mentioned medicine juice being done filtration treatment, after being heated to boiling, use slow fire instead, being constantly stirred to medicinal liquid is thick paste, obtains concentrated medicament;

(4) by the medical filtration that upper step process obtains, then pour the heating of frying pan maintenance slow fire into, and constantly stir, be stirred to and mention stirring rod medicine juice extension flag, stop heating both to obtain paste.

After described step (4) obtains medlar health preserving cream, spend when also not leaving while hot, pour into fast and to have cleaned and in the container of sterilizing, Temperature fall at ambient temperature, until medlar health preserving cream temperature is cool to room temperature, then row capping is preserved, and at room temperature the holding time can more than 6 months.

Be further illustrated below by way of listing several example effect to this medlar health preserving cream taking medlar health preserving cream,

(1) Li Xiuying, sex: female, age: 70 years old, medical history: chronic gastritis 15 years, is interrupted and takes omeprazole capsule and domperidone tablet, occasionally has gastral cavilty portion uncomfortable, hypertension history 8 years, oral nifedipine slow-release sheet 10mg/ time, every day 2 times and enalapril 10mg/ time, every day 1/ time, blood pressure maintains 140-160/90-100mmHg at ordinary times, fat of previously having a blood test is high, and do not give treatment, diet suitably controls.

Patient takes the cream time: amount to January from 2013-06-18 to 2013 year 07-18.

Patient takes cream method: patient per gets after medlar health preserving cream 10ml adds water to 100ml and drinks, every day 1 time.

The former antihypertensive drugs of following the service during patient takes medlar health preserving cream, periodic monitoring blood pressure.

Health guidance during taking medlar health preserving cream: less salt, low fat, glucose-diet, fasting raw food stimulates food, and smooth feelings will, moderate exercise, avoids suffering from cold.

Patient takes main clinical manifestation before medlar health preserving cream: dizzy, dizzy, tinnitus, and nighttime sleep is poor, defecation normally, red tongue, stringy and thready pulse.Have a medical check-up: BP150/90mmHg, heart rate 80 beats/min, two lung (-).Liver and kidney merit is looked into normal before taking medlar health preserving cream; Blood glucose 6.1mmol/L; Triglyceride 2.80mmol/L; T-CHOL 6.8mmol/L; HDL1 .23mmol/L; Low density lipoprotein, LDL 4.53mmol/L.

Patient takes main clinical manifestation after medlar health preserving cream January: dizzy, is dizzyly comparatively before clearly better, and tinnitus disappears, and nighttime sleep improves, and body of the tongue is slightly red, stringy pulse.Fluctuation of blood pressure is detected at about 120-130/80-90mmhg during taking cream.Liver and kidney merit is checked normal after taking plaster; Blood glucose 5.2mmol/L; Triglyceride 2.10mmol/L; T-CHOL 5.1mmol/L; HDL1 .51mmol/L; Low density lipoprotein, LDL 3.31mmol/L.

Sum up: patient to take before and after medlar health preserving cream dizzy, dizzy, tinnitus, and nighttime sleep has clear improvement, blood pressure also controls well simultaneously, and blood fat obviously declines, and the side effect such as to damage, get angry without Liver and kidney merit.

(2) Liu Xuejuan, sex: female, age: 35 years old, medical history: postoperative 1 year of ovarian cyst surgical removal, postoperative eumenorrhea.Without other chronic medical histories and infection medical history.

Patient takes the cream time: amount to January from 2013-06-21 to 2013 year 07-21.

Health guidance during patient takes medlar health preserving cream: general food, fasting raw food stimulates and greasy food, and smooth feelings will, moderate exercise, avoids suffering from cold.

Patient takes main clinical manifestation before medlar health preserving cream: fatiguability, and dizzy, the dizzy and tinnitus of paroxysmal, after tired obviously, nighttime sleep is poor, and normally, body of the tongue is light red, deep-thready pulse for defecation.Have a medical check-up: BP90/60mmHg, heart rate 80 beats/min, two lung (-).Liver and kidney merit is looked into normal before taking medlar health preserving cream; Blood glucose 5.2mmol/L, blood fat is normal.Hematochrome is normal.

Main clinical manifestation after patient takes medlar health preserving cream January: dizzy, dizzy and tinnitus disappears, and fatiguability sense disappears, and nighttime sleep improves, and body of the tongue is light red, thready pulse.Fluctuation of blood pressure is detected at about 90-100/60-70mmhg during taking cream.Liver and kidney merit is checked normal after taking plaster; Blood glucose is normal.

Sum up: patient takes feeling of fatigue after medlar health preserving cream and disappears, dizzy, dizzy, tinnitus, and nighttime sleep has clear improvement, simultaneously blood pressure comparatively before go up, blood glucose and blood fat normal, without the infringement of hepatic and renal function, symptom of getting angry without endocrine regulation, aphtha of the mouth and tongue etc.

(3) Zhou Jianmin, sex: man, age: 43 years old, medical history: hypertension history 5 years, oral nifedipine slow-release sheet 10mg/ time, every day 2 times, enalapril 10mg/ time, every day 1 time, enteric coated aspirin 0.1g, every day 1 time, blood pressure maintains 140-160/100-110mmHg at ordinary times.Previously without other chronic medical history and infection medical history.

Patient takes the cream time: amount to January from 2013-06-08 to 2013 year 07-08.

Health guidance during taking medlar health preserving cream: less salt, low fat diet, fasting raw food stimulates food, and smooth feelings will, moderate exercise, avoids suffering from cold.

Patient takes main clinical manifestation before medlar health preserving cream: dizzy, nighttime sleep can, appetite is good, and defecation is normal, red tongue, stringy pulse.Have a medical check-up: BP150/105mmHg, heart rate 80 beats/min, two lung (-).Liver and kidney merit is looked into normal before taking medlar health preserving cream; Blood glucose 5.2mmol/L; Triglyceride 2.90mmol/L; T-CHOL 6.5mmol/L; HDL1 .65mmol/L; Low density lipoprotein, LDL 4.53mmol/L.

Patient takes main clinical manifestation after medlar health preserving cream January: dizziness is clearly better, red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 120-130/80-90mmhg during taking cream.Liver and kidney merit is checked normal after taking plaster; Blood glucose 5.5mmol/L; Triglyceride 2.10mmol/L; T-CHOL 5.2mmol/L; HDL1 .16mmol/L; Low density lipoprotein, LDL 3.09mmol/L.

Sum up: patient take medlar health preserving cream before and after dizziness have clear improvement, simultaneously controlling of blood pressure is good, and blood fat obviously declines, and damages without Liver and kidney merit.

(4) Wang little Feng, sex: female, age: 40 years old, medical history: without chronic medical history and infection medical history.

Patient takes the cream time: amount to January from 2013-06-20 to 2013 year 07-20.

Patient takes main clinical manifestation before medlar health preserving cream: hyperhidrosis susceptible, fatigue and weak, dim complexion, and uneasy sleeping at night, has a dizzy spell, after tired obviously, and red tongue, white and thin fur, thready pulse without strength.Have a medical check-up: BP80/50mmhg.Heart rate 80 beats/min, two lung (-).Before taking medlar health preserving cream, Liver and kidney merit is normal; Blood glucose 3.4mmol/L; Triglyceride 1.30mmol/L; T-CHOL 4.3mmol/L; HDL1 .36mmol/L; Low density lipoprotein, LDL 2.64mmol/L.

Patient takes main clinical manifestation after medlar health preserving cream January: feeling of fatigue disappears, and sleep obviously improves, and period in a medicine is caught a cold, and sweating is obviously alleviated, and dizzyly takes a turn for the better, complexion comparatively before ruddy, body of the tongue is light red, white and thin fur, stringy and thready pulse.Have a medical check-up: BP100/65mmHg, heart rate 78 beats/min, two lung (-). check Liver and kidney merit after taking plaster normal, blood glucose 4.3mmol/L; Triglyceride 1.70mmol/L; T-CHOL 4.2mmol/L; HDL1 .42mmol/L; Low density lipoprotein, LDL 2.21mmol/L.

Sum up: patient takes feeling of fatigue after medlar health preserving cream and disappears, and susceptible is alleviated, and dizzy and nighttime sleep has clear improvement, and complexion takes a turn for the better, simultaneously blood pressure comparatively before go up, without the infringement of hepatic and renal function.

(5) Han Xuemei, sex female, 45 years old age, medical history: nothing.

Take the cream time: 2013-04-14 to 2013 year 07-14, once a day, each 10ml adds water to 100ml and drinks.

Main clinical manifestation and lab testing contrast during patient consumes:

Take front main clinical manifestation: hyperhidrosis susceptible, fatiguability, dreaminess is insomnia, and two is just normal, red tongue, few tongue, thready and rapid pulse.Have a medical check-up: BP100/70mmhg.Heart rate 83 beats/min, two lung (-).

Lab testing Liver and kidney merit, electrolyte are normal; Blood glucose 3.6mmol/L; Triglyceride 2.6mmol/L; T-CHOL 5.0mmol/L; HDL1 .36mmol/L; Low density lipoprotein, LDL 2.64mmol/L.

Take medlar health preserving cream one and a half months, main clinical manifestation, tired and sleep makes moderate progress, and sweating takes a turn for the better, red tongue, white and thin fur, thready pulse.Have a medical check-up: BP100/75mmhg, heart rate 80 beats/min, two lung (-).

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 3.5mmol/L; Triglyceride 2.01mmol/L; T-CHOL 4.4mmol/L; HDL1 .32mmol/L; Low density lipoprotein, LDL 2.13mmol/L.

After taking medlar health preserving cream March, main clinical manifestation, tired and sleep obviously improves, and period in a medicine is caught a cold, and sweating is obviously alleviated, and body of the tongue is light red, white and thin fur, thready pulse.Have a medical check-up: BP100/75mmhg, heart rate 78 beats/min, two lung (-).

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 4.6mmol/L; Triglyceride 1.8mmol/L; T-CHOL 4.1mmol/L; HDL1 .52mmol/L; Low density lipoprotein, LDL 2.04mmol/L.

Implement case two: the present invention is a kind of medlar health preserving cream of medicine-food two-purpose, comprises following raw material, its composition and mass fraction be, Fructus Lycii 8 parts, Rhizoma Polygonati 0.5 part, Radix Panacis Quinquefolii 0.5 part, day essence grass 0.5 part.

Prepare the method for above-mentioned medicine-food two-purpose medlar health preserving cream, comprise the steps, the Fructus Lycii of 8 parts, the Rhizoma Polygonati of 0.5 part, the Radix Panacis Quinquefolii of 0.5 part, the sky careless water of essence of 0.5 part are cleaned five times, and then soak 2 ~ 4h by (1), and above-mentioned number is mass fraction;

(2) Fructus Lycii, Rhizoma Polygonati, Radix Panacis Quinquefolii is 1. decocted: the Fructus Lycii handled well through upper step is inserted frying pan, Rhizoma Polygonati, Radix Panacis Quinquefolii are chopped into lamellar and insert frying pan respectively again, in each frying pan discharge water and be 10:1 with the ratio of quality and the number of copies of medical material, medicine juice is taken out after each decoction 2h, adding water again makes the quality proportioning of water and medical material constant, steaming and decocting three times, finally mixes all medicine juice altogether;

2. sky essence grass is decocted, the sky essence grass handled well through (1) is inserted in frying pan, the water added in frying pan all exceeds medical material 3 ~ 5cm, first soaks 6 ~ 8 hours, then decocts 2 times, each elder generation boils with high heat, with slow fire boiling 2 hours after boiling, filter and obtain medicine juice, before second time decocts, wanting supplementing water to ensure, it is highly constant, filter the medicinal liquid obtained after twice decoction to be incorporated in above-mentioned Fructus Lycii admixing medical solutions, be placed in container and place 6h;

After described step (4) obtains medlar health preserving cream, spend when also not leaving while hot, pour into fast and to have cleaned and in the container of sterilizing, Temperature fall at ambient temperature, until medlar health preserving cream temperature is cool to room temperature, row capping is preserved again, and then the holding time is no more than 1 year half to insert the chill space of 2 ~ 8 DEG C.

The beneficial effect that the present embodiment medlar health preserving cream is described is tested below by way of carrying out immunity of organism to mice.

1, on the impact of mouse blood Carbon clearance rate

Mice 60, male and female half and half, are divided into 6 groups (NS, medlar liquid, transfer factor group, YQD, YQZ, YQX groups) at random, often organize 10.Continuous gavage 10d.After last administration 30 points, mice is by every 10g body weight tail vein injection Chinese ink 0.1mL (normal saline dilution).Timing immediately after injection, respectively at after injection the 2nd, 10min capillary pipette gets blood 20 μ L from vena orbitalis posterior clump respectively, is dissolved in 1mL0.1%Na ₂cO ₃shake up in solution, densitometric (OD value).Mice cervical dislocation is lethal, and get liver, spleen, thymus weighs, calculating K=(LgOD ₁-LgOD ₂)/(t ₂-t ₁), Carbon clearance rate (x ± n) n=10, x representative be the meansigma methods of speed,

Remarks: compare * p<0.05 with normal saline group, * * p<0.01.

2, Organs Weight is mensuration

Gauge index after Thymus and spleen is weighed, thymus index=(thymic weight (mg)/mice weights (g)) × 10, index and spleen index=(spleen weight (mg)/mice weights (g)) × 10, immune organ weight (x ± n) n=10

Remarks: compare * p<0.05 with normal saline group; * p<0.01.

Above-mentioned result of the test shows: carbon clearance test be according to carbon granules in blood flow by the speed cleaned up, judge the function of monocytes/macrophages.After graininess foreign body vein injects Mouse Blood circulation, can be removed by mononuclear cell rapidly, mainly by the macrophage phagocytic of settling down at liver and spleen.When foreign body amount is constant, in its blood flow, clearance of particles rate can reflect monocytes/macrophages phagocytic function.Carbon clearance rate declines, and the function of reflection monocytes/macrophages reduces.Thymus and spleen is the main immune organ of body, and the change of its relative weight occupies critical role in immunity evaluation, and Thymus and spleen index significantly reduces, and reflects immune function depression.Result: the medlar health preserving cream of various dose all can enhancing immune function of mice in various degree.The each dosage group of medlar health preserving cream comparatively normal saline group mouse blood Carbon clearance rate increases (P<0.05), and mouse thymus, index and spleen index comparatively normal saline group obviously increase (P<0.01).Conclusion: medlar health preserving cream can strengthen mice body's immunity.

Below have chosen the case that part human body uses medlar health preserving cream, effect of medlar health preserving cream be further illustrated,

(1) Liu Lixia, sex female, 53 years old age, medical history without.

Take 2013-04-18 to 2013 year cream time 07-18 once a day, each 10ml adds to 200ml diseases caused by retention of fluid and uses.

Main clinical manifestation and lab testing contrast during patient consumes, before taking, main clinical manifestation: hyperhidrosis susceptible, fatigue and weak, dim complexion, uneasy sleeping at night, has a dizzy spell, red tongue, white and thin fur, thready pulse without strength.Have a medical check-up: BP120/80mmhg.Heart rate 80 beats/min, two lung (-).

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 7.4mmol/L; Triglyceride 2.6mmol/L; T-CHOL 5.0mmol/L; HDL1 .36mmol/L; Low density lipoprotein, LDL 2.64mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation, having a dizzy spell and sleeping makes moderate progress, and spirit is comparatively front to take a turn for the better, and sweating takes a turn for the better, and complexion is comparatively front to take a turn for the better, red tongue, white and thin fur, stringy and thready pulse.Have a medical check-up: BP120/75mmhg, heart rate 80 beats/min, two lung (-).

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 6.6mmol/L; Triglyceride 3.2mmol/L; T-CHOL 5.3mmol/L; HDL1 .14mmol/L; Low density lipoprotein, LDL 2.71mmol/L.

After edible medlar health preserving cream March, main clinical manifestation, tired and sleep obviously improves, period in a medicine is caught a cold, and sweating is obviously alleviated, and body of the tongue is light red, white and thin fur, thready pulse.Have a medical check-up: BP100/75mmhg, heart rate 78 beats/min, two lung (-).

Lab testing Liver and kidney merit, electrolyte are normal; Blood glucose 5.6mmol/L; Triglyceride 2.1mmol/L; T-CHOL 4.5mmol/L; HDL1 .37mmol/L; Low density lipoprotein, LDL 2.21mmol/L.

(2) Zou Xingyi, sex man, 52 years old age, medical history without.

Take 2013-04-17 to 2013 year cream time 07-17, once a day, each 10ml adds water to 200ml and drinks.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, be interrupted headache, fatiguability, nighttime sleep can, red tongue, yellow and thin fur, stringy and thready pulse.Have a medical check-up: BP130/80mmhg.Heart rate 80 beats/min, two lung (-).

Lab testing Liver and kidney merit, electrolyte are normal; Blood glucose 6.2mmol/L; Triglyceride 3.5mmol/L; T-CHOL 5.2mmol/L; High density lipoprotein 0.75mmol/L; Low density lipoprotein, LDL 2.39mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, headache takes a turn for the better, fatiguability comparatively before alleviate, nighttime sleep can, red tongue, yellow and thin fur, stringy and thready pulse.Have a medical check-up: BP120/75mmhg, heart rate 78 beats/min, two lung (-).

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 5.4mmol/L; Triglyceride 2.70mmol/L; T-CHOL 4.1mmol/L; High density lipoprotein 0.88mmol/L; Low density lipoprotein, LDL 1.99mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy, headache, fatiguability transference cure, nighttime sleep can, red tongue, yellow and thin fur, stringy pulse.Have a medical check-up: BP120/75mmhg, heart rate 78 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.0mmol/L; Triglyceride 2.0mmol/L; T-CHOL 4.0mmol/L; HDL1 .36mmol/L; Low density lipoprotein, LDL 1.48mmol/L.

(3) Zhang Yaohong, sex man, 45 years old age, medical history without.

Take 2013-04-14 to 2013 year cream time 07-14, once a day, each 10ml, adds water to 200ml and drinks.

Main clinical manifestation and lab testing contrast during patient consumes, take front main clinical manifestation: paroxysmal is dizzy, fatiguability, red tongue, tongue is white, stringy pulse.Have a medical check-up: BP130/90mmhg, heart rate 88 beats/min, two lung (-).

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 5.2mmol/L; Triglyceride 3.2mmol/L; T-CHOL 5.4mmol/L; High density lipoprotein 0.78mmol/L; Low density lipoprotein, LDL 2.64mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, fatiguability is comparatively front to take a turn for the better, red tongue, few tongue, stringy pulse.Fluctuation of blood pressure is detected at about 120-130/80-85mmhg during taking cream.

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 4.1mmol/L; Triglyceride 2.70mmol/L; T-CHOL 4.0mmol/L; High density lipoprotein 0.83mmol/L; Low density lipoprotein, LDL 1.94mmol/L.

Edible medlar health preserving cream three months, main clinical manifestation, dizzy disappearance, fatiguability improves, and body of the tongue is light red, white and thin fur, stringy pulse.Fluctuation of blood pressure is detected at about 110-120/70-80mmhg during taking cream.

Lab testing, Liver and kidney merit, electrolyte are normal; Blood glucose 4.2mmol/L; Triglyceride 1.93mmol/L; T-CHOL 4.2mmol/L; HDL1 .38mmol/L; Low density lipoprotein, LDL 1.54mmol/L.

(4) Sun Fuqin, sex female, 58 years old age, medical history without.

Take 2013-4-09 to 2013 year cream time 07-09, once a day, each 10ml adds water to 200ml and drinks.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, tinnitus, hyperhidrosis, susceptible, sleep poor, hectic fever in the afternoon, red tongue, thready and rapid pulse.Have a medical check-up: BP120/80mmhg, heart rate 98 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.5mmol/L; Triglyceride 3.80mmol/L; T-CHOL 6.1mmol/L; HDL1 .70mmol/L; Low density lipoprotein, LDL 2.67mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, take a turn for the better before tinnitus and sleep comparatively, sweating takes a turn for the better, and hectic fever in the afternoon takes a turn for the better, red tongue, thready pulse.Fluctuation of blood pressure is detected at about 110-112/75-80mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.3mmol/L; Triglyceride 2.70mmol/L; T-CHOL 5.4mmol/L; HDL1 .95mmol/L; Low density lipoprotein, LDL 2.35mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy, tinnitus and sleep are comparatively before clearly better, and sweating obviously improves, and nearly January has no flu, red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 110-120/70-80mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.5mmol/L; Triglyceride 1.8mmol/L; T-CHOL 4.5mmol/L; HDL2 .15mmol/L; Low density lipoprotein, LDL 1.83mmol/L.

(5) Zhang Huilan, sex female, 69 years old age, medical history without.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: have a dizzy spell, hyperhidrosis, night obviously, susceptible, fatiguability, sleep poor, red tongue, deep-thready pulse.Have a medical check-up: BP110/80mmhg, heart rate 88 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 6.1mmol/L; Triglyceride 2.4mmol/L; T-CHOL 5.3mmol/L; HDL1 .13mmol/L; Low density lipoprotein, LDL 3.08mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: have a dizzy spell and sleep comparatively and take a turn for the better, sweating takes a turn for the better, and feeling of fatigue is alleviated, red tongue, deep-thready pulse.Fluctuation of blood pressure is detected at about 110-115/75-80mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.6mmol/L; Triglyceride 2.10mmol/L; T-CHOL 4.90mmol/L; High density lipoprotein 0.92mmol/L; Low density lipoprotein, LDL 2.59mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy, dizzy and sleep is comparatively before clearly better, and sweating obviously improves, and nearly January has no flu, red tongue, thready pulse.Fluctuation of blood pressure is detected at about 110-120/75-80mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.9mmol/L; Triglyceride 1.71mmol/L; T-CHOL 4.35mmol/L; High density lipoprotein 0.78mmol/L; Low density lipoprotein, LDL 1.89mmol/L.

Embodiment three: the medlar health preserving cream of a kind of medicine-food two-purpose that the present invention sends, comprises following raw material, its composition and mass fraction be, Fructus Lycii 20 parts, Rhizoma Polygonati 6 parts, Radix Panacis Quinquefolii 8 part, day essence grass 5 parts, Cortex Lycii 1 part.

Prepare the method for above-mentioned medicine-food two-purpose medlar health preserving cream, comprise the steps, (1) Fructus Lycii of 20 parts, the Rhizoma Polygonati of 6 parts, the Radix Panacis Quinquefolii of 8 parts, the sky essence grass of 5 parts, the Cortex Lycii water of 1 part are cleaned five times, and then soaks 2 ~ 4h, above-mentioned number is mass fraction;

2. sky essence grass, Cortex Lycii is decocted, the sky essence handled well through (1) is careless, Cortex Lycii is inserted in frying pan respectively, the water added in frying pan all exceeds medical material 3 ~ 5cm, first soaks 6 ~ 8 hours, then decocts 2 times, each elder generation boils with high heat, with slow fire boiling 2 hours after boiling, filter and obtain medicine juice, before second time decocts, wanting supplementing water to ensure, it is highly constant, filter the medicinal liquid obtained after twice decoction to be incorporated in above-mentioned Fructus Lycii admixing medical solutions, be placed in container and place 6h;

Effect that following selected part hyperlipemic patients is taken after this medlar health preserving cream is explained,

(1) Kang Hua, sex: man, the age: 43 years old, medical history: hyperlipidemia medical history 2 years, be once interrupted and take simvastatin 10mg/ time, every day 1/ time, blood fat controls bad, previously without hypertension and diabetic history, denies other chronic medical history and infects medical history.

Patient takes the cream time: amount to January from 2013-06-06 to 2013 year 07-06.

Patient takes cream method: patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

Patient did not take fat-reducing medicament during taking medlar health preserving cream, controlled feed high lipid food.

Patient takes main clinical manifestation before medlar health preserving cream: dizzy, easily perspires, nighttime sleep can, appetite is good, and defecation is normal, red tongue, stringy pulse.Have a medical check-up: BP130/90mmHg, heart rate 80 beats/min, two lung (-).Liver and kidney merit is looked into normal before taking medlar health preserving cream; Blood glucose 5.2mmol/L; Triglyceride 3.80mmol/L; T-CHOL 8.4mmol/L; HDL1 .65mmol/L; Low density lipoprotein, LDL 5.02mmol/L.

Patient takes main clinical manifestation after medlar health preserving cream January: dizziness is clearly better, and sweating takes a turn for the better, red tongue, stringy pulse.Take measuring blood pressure 120/80mmHg after cream.Liver and kidney merit is checked normal after taking plaster; Blood glucose 5.5mmol/L; Triglyceride 2.70mmol/L; T-CHOL 6.5mmol/L; HDL1 .16mmol/L; Low density lipoprotein, LDL 4.15mmol/L.

Sum up: patient take medlar health preserving cream before and after dizziness have clear improvement, blood pressure is normal, and blood fat obviously declines, and damages without Liver and kidney merit.

(2) Meng Zhanbiao, sex man, 59 years old age, medical history diabetes 5 years, application Novolin 50R, coronary heart disease 2 years.

Take 2013-4-07 to 2013 year cream time 07-07, get after medlar health preserving cream 10ml adds water to 200ml at every turn and drink, every day 1 time.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, fatiguability, paroxysmal chest distress and palpitation symptoms, and once, thirsty, susceptible, sleeps poor, red tongue, stringy and thready pulse in a few days outbreak.Have a medical check-up: BP140/90mmhg, heart rate 80 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 7.0mmol/L; Triglyceride 2.40mmol/L; T-CHOL 4.2mmol/L; High density lipoprotein 0.88mmol/L; Low density lipoprotein, LDL 2.23mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation, dizzy and thirsty improvement, occasionally has uncomfortable in chest, cardiopalmus, red tongue, stringy and thready pulse.Fluctuation of blood pressure is detected at about 130-135/80-90mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 6.4mmol/L; Triglyceride 2.20mmol/L; T-CHOL 4.0mmol/L; High density lipoprotein 0.79mmol/L; Low density lipoprotein, LDL 2.02mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizziness is clearly better, thirsty disappearance, occasionally has chest distress and palpitation symptoms, short duration red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 120-130/80mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.6mmol/L; Triglyceride 1.98mmol/L; T-CHOL 4.1mmol/L; High density lipoprotein 0.85mmol/L; Low density lipoprotein, LDL 1.91mmol/L.

(3) fourth power, sex man, 59 years old age, medical history: diabetes 5 years, application Novolin 50R, coronary heart disease 2 years.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy and thirsty improvement, occasionally has uncomfortable in chest, cardiopalmus, red tongue, stringy and thready pulse.Fluctuation of blood pressure is detected at about 130-135/80-90mmhg during taking cream.

Embodiment four: the medlar health preserving cream of a kind of medicine-food two-purpose that the present invention sends, comprises following raw material, its composition and mass fraction be, Fructus Lycii 15 parts, Rhizoma Polygonati 3 parts, Radix Panacis Quinquefolii 3 part, day essence grass 2 parts, Cortex Lycii 10 parts, Chinese wolfberry carpopodium 0.5 part.

Prepare the method for above-mentioned medicine-food two-purpose medlar health preserving cream, comprise the steps, (1) Fructus Lycii of 15 parts, the Rhizoma Polygonati of 3 parts, the Radix Panacis Quinquefolii of 3 parts, sky essence grass, the Cortex Lycii of 10 parts, the Chinese wolfberry carpopodium water of 0.5 part of 2 parts are cleaned five times, and then soaking 2 ~ 4h, above-mentioned number is mass fraction;

2. sky essence grass, Cortex Lycii, Chinese wolfberry carpopodium is decocted, the sky essence grass handled well through (1), Cortex Lycii, Chinese wolfberry carpopodium are inserted in frying pan respectively, the water added in frying pan all exceeds medical material 3 ~ 5cm, first soaks 6 ~ 8 hours, then decocts 2 times, each elder generation boils with high heat, with slow fire boiling 2 hours after boiling, filter and obtain medicine juice, before second time decocts, wanting supplementing water to ensure, it is highly constant, filter the medicinal liquid obtained after twice decoction to be incorporated in above-mentioned Fructus Lycii admixing medical solutions, be placed in container and place 6h;

(3) be again placed in frying pan after above-mentioned medicine juice being done filtration treatment, after being heated to boiling, using slow fire instead, constantly stir medicinal liquid, obtain concentrated medicament;

After described step (4) obtains medlar health preserving cream, spend when also not leaving while hot, pour into fast and to have cleaned and in the container of sterilizing, Temperature fall at ambient temperature, until medlar health preserving cream temperature is cool to room temperature, row capping is preserved again, and then the holding time is no more than 1 year to insert the chill space of 2 ~ 8 DEG C.

The effect of case to medlar health preserving cream of the present invention of following selected part hypertension, hyperglycemic patients is further illustrated.

One, the selection of clinical observation on the therapeutic effect crowd is as follows: (1) select age 30-80 year between, have fatiguability or health check-up to have blood glucose, blood fat rising person; Chinese medical discrimination belongs to the hepatic and renal YIN deficiency or type of deficiency of both QI and YIN crowd as observation group; (2) without severe primary disease and psychotics such as cardiovascular and cerebrovascular vessel, liver, kidney and hemopoietic systems.

Two, clinical data: select 50 routine blood glucose raise crowds (wherein male 28 example, women 22 example, the age 45-75 year between, course of disease several months to the several years, not etc. range of blood sugar was not at below 11mmol/L, and wherein complicated hypertension person 18 example, merges hyperlipidemia person 14 example).Select 50 routine hyperlipidemia populations (wherein male 29 example, women 21 example, the age 40-75 year between, course of disease several months to the several years, not etc. wherein complicated hypertension person 24 example, did not merge hyperglycemia 12 example).Select 120 routine fatiguability crowds (wherein male 60 example, women 60 example, the age 30-80 year between, course of disease several months to the several years wait wherein complicated hypertension person 24 example, merge hyperglycemia 32 example, merge hyperlipidemia 28 example).

Three, instructions of taking: medlar health preserving cream 10ml/ time, drinks on an empty stomach after the 100-200ml that adds water dilutes, every day 1 time, serve on January.Remarks: period in a medicine continues with former oral dose protopathy medicine to control blood glucose and blood pressure.

Four, observational technique: the detection of the conventional and hepatic and renal function of conventional promoting the circulation of blood, blood fat, blood glucose before experiment, will meet choice criteria person and include the object of observation in.Patient follows up a case by regular visits to the situation after taking and side effect after taking first quarter moon, follow up a case by regular visits to after January, parallel Liver and kidney merit and blood glucose, lipids detection, observe the curative effect.

Five, efficacy assessment standard: effectively: main clinic symptoms is alleviated, in blood fat monitoring, triglyceride, T-CHOL, low density lipoprotein, LDL any one decrease beyond 20% before and after taking, or high density lipoprotein increases to over 20%; Blood glucose is relatively stable is effective; Invalid: clinical symptoms without alleviation, blood fat monitoring in triglyceride, T-CHOL, low density lipoprotein, LDL none take before and after under be reduced to 20%; Blood glucose fluctuation is more invalid.

Six, therapeutic outcome:

1, the therapeutic outcome of hyperglycemia: see following to hyperglycemia population clinical efficacy statistical table,

Observe treatment total number of persons (people)	Effectively (people)	Invalid (people)	Effective percentage (%)
				50	45	5	90

Through t inspection, treatment group is done to compare before and after treatment, all has significant difference (p < 0.01), illustrates that I has good auxiliary therapeutic action to the hepatic and renal YIN deficiency or type of deficiency of both QI and YIN hyperglycemia by institute's self-control medlar health preserving cream.

2. the therapeutic outcome of hyperlipidemia: see following to people with hyperlipidemia clinical efficacy statistical table,

Observe treatment total number of persons (people)	Effectively (people)	Invalid (people)	Effective percentage (%)
				50	42	8	84

Through t inspection, treatment group is done to compare before and after treatment, all has significant difference (p < 0.01), illustrates that I has good auxiliary therapeutic action to the hepatic and renal YIN deficiency or type of deficiency of both QI and YIN hyperlipidemia by institute's self-control medlar health preserving cream.

3, fatigable therapeutic outcome: see following to fatiguability crowd clinical efficacy statistical table,

Observe treatment total number of persons (people)	Effectively (people)	Invalid (people)	Effective percentage (%)
				120	114	6	95

Through t inspection, treatment group is done to compare before and after treatment, all has significant difference (p < 0.01), illustrates that I has good auxiliary therapeutic action to the hepatic and renal YIN deficiency or type of deficiency of both QI and YIN fatiguability by institute's self-control medlar health preserving cream.

Untoward reaction: we amount to and observe case 150 example (because some patients in observation group has fatigue and hyperglycemia, hyperlipidemia the phenomenon of depositing), do not find obvious adverse reaction and toxic and side effects in observing time.

Below comform selected part hypertension in multiple-case, hyperglycemia sufferer clinical case effect of medlar health preserving cream of the present invention is described.

(1) Yang Lixin, sex man, at 60 years old age, medical history: diabetic history 2 years, most high fasting blood glucose 12.2mmol/L, oral administration of metformin 0.25g/ time, every day 3 times, fasting glucose fluctuates between 7-9mmol/L.Without hypertension and other chronic disease histories and infect medical history.

Patient takes the cream time: amount to January from 2013-06-15 to 2013 year 07-15.

Patient continues during taking medlar health preserving cream and takes metformin, periodic monitoring blood glucose with former dosage.

Patient takes main clinical manifestation before medlar health preserving cream: fatiguability, polydipsia polyuria, appetite can, stool is normal, dizzy, sleep can, red tongue, few Tianjin, thready and rapid pulse.Have a medical check-up: BP120/80mmHg, heart rate 95 beats/min, two lung (-).Liver and kidney merit is looked into normal before taking medlar health preserving cream; Blood glucose 8.7mmol/L; Blood fat is normal.

Patient takes main clinical manifestation after medlar health preserving cream January: fatiguability disappears, appetite can, stool is normal, dizzyly alleviates, sleep can, the light red white and thin fur of body of the tongue, stringy and thready pulse.Have a medical check-up: BP120/80mmHg, heart rate 85 beats/min, two lung (-).Liver and kidney merit is looked into normal after taking medlar health preserving cream; Fasting glucose 5.4mmol/L; Blood fat is normal.

(2) Dong Shuxia, sex female, at 50 years old age, medical history: hypertension history 2 years, oral nifedipine slow-release sheet 10mg/ time, every day 2 times and captopril 25mg/ time, every day 2/ time, blood pressure maintains 140-150/90-100mmHg at ordinary times.Previously without other chronic medical history and infection medical history.

Patient takes main clinical manifestation before medlar health preserving cream: dizzy, paroxysmal vertigo, nighttime sleep can, appetite is general, and two is just normal, red tongue, stringy pulse.Have a medical check-up: BP150/100mmHg, heart rate 80 beats/min, two lung (-).Liver and kidney merit is looked into normal before taking medlar health preserving cream; Blood glucose 5.2mmol/L; Triglyceride 3.70mmol/L; T-CHOL 7.6mmol/L; HDL1 .05mmol/L; Low density lipoprotein, LDL 4.27mmol/L.

Patient takes main clinical manifestation after medlar health preserving cream January: dizziness is clearly better, dizzy disappearance, sleep can, red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 120-130/80-90mmhg during taking cream.Liver and kidney merit is checked normal after taking plaster; Blood glucose 5.5mmol/L; Triglyceride 2.20mmol/L; T-CHOL 5.6mmol/L; HDL1 .41mmol/L; Low density lipoprotein, LDL 3.42mmol/L.

Sum up: patient take medlar health preserving cream before and after dizziness have clear improvement, simultaneously blood pressure also controls well, and blood fat obviously declines, and damages without Liver and kidney merit.

(3) Liu Yuechun, sex female, 47 years old age, medical history hypertension history 3 years.

Take 2013-04-14 to 2013 year cream time 07-14, patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, hyperhidrosis, uneasy sleeping at night, irritable, red tongue, few tongue, stringy and thready pulse.Have a medical check-up: BP150/100mmhg, heart rate 88 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.6mmol/L; Triglyceride 2.4mmol/L; T-CHOL 7.0mmol/L; HDL1 .18mmol/L; Low density lipoprotein, LDL 4.14mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, hyperhidrosis, uneasy sleeping at night takes a turn for the better, and irritable alleviates, red tongue, few tongue, stringy and thready pulse.Fluctuation of blood pressure is detected at about 135-145/90-95mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.8mmol/L; Triglyceride 1.60mmol/L; T-CHOL 5.6mmol/L; HDL1 .29mmol/L; Low density lipoprotein, LDL 3.58mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy, hyperhidrosis, uneasy sleeping at night obviously improves, and emotion takes a turn for the better, and body of the tongue is light red, white and thin fur, and arteries and veins is string slightly.Fluctuation of blood pressure is detected at about 120-130/80-90mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.4mmol/L; Triglyceride 1.33mmol/L; T-CHOL 4.8mmol/L; HDL1 .48mmol/L; Low density lipoprotein, LDL 2.84mmol/L.

(4) name Zhang Zhen is firm, sex man, 63 years old age, medical history: hypertension history 6 years, cerebral infarction 1 year.

Take 2013-04-15 to 2013 year cream time 07-15, patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, dizzy, nighttime sleep is poor, the mile abnormality during limb activity of right side, red tongue, stringy and thready pulse.Have a medical check-up: BP160/100mmhg, heart rate 80 beats/min, two lung (-). right side lower-limb muscular strength 4 grades.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 6.2mmol/L; Triglyceride 2.01mmol/L; T-CHOL 6.8mmol/L; HDL1 .25mmol/L; Low density lipoprotein, LDL 4.34mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, dizzy and sleep is comparatively front to take a turn for the better, red tongue, stringy and thready pulse.Fluctuation of blood pressure is detected at about 145-150/90-95mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.0mmol/L; Triglyceride 0.9mmol/L; T-CHOL 5.7mmol/L; HDL1 .51mmol/L; Low density lipoprotein, LDL 3.78mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy, dizzy and sleep is comparatively before clearly better, red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 130-140/80-90mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.6mmol/L; Triglyceride 1.2mmol/L; T-CHOL 4.6mmol/L; HDL1 .32mmol/L; Low density lipoprotein, LDL 2.94mmol/L.

(5) Meng Jinju, sex female, at 70 years old age, medical history: hypertension history 10 years, cerebral infarction 3 years, takes 2013-04-15 to 2013 year cream time 07-15, and patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, dizzy, sleep poor, mile abnormality when left limb is movable, red tongue, stringy and thready pulse.Have a medical check-up: BP165/100mmhg, heart rate 90 beats/min, two lung (-). left side lower-limb muscular strength 4 grades.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 6.5mmol/L; Triglyceride 2.84mmol/L; T-CHOL 6.47mmol/L; HDL1 .18mmol/L; Low density lipoprotein, LDL 3.58mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, dizzy and sleep is comparatively front to take a turn for the better, red tongue, stringy and thready pulse.Fluctuation of blood pressure is detected at about 140-150/90-95mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.6mmol/L; Triglyceride 2.20mmol/L; T-CHOL 5.3mmol/L; HDL1 .29mmol/L; Low density lipoprotein, LDL 3.01mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy, dizzy and sleep is comparatively before clearly better, red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 130-145/80-90mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.9mmol/L; Triglyceride 1.72mmol/L; T-CHOL 4.8mmol/L; HDL1 .45mmol/L; Low density lipoprotein, LDL 2.37mmol/L.

Embodiment five: the medlar health preserving cream of a kind of medicine-food two-purpose that the present invention sends, comprises following raw material, its composition and mass fraction be, Fructus Lycii 17 parts, Rhizoma Polygonati 0.8 part, Radix Panacis Quinquefolii 4 part, day essence grass 4 parts, Cortex Lycii 5 parts, Chinese wolfberry carpopodium 8 parts, 0.5 part, Radix Glycyrrhizae.

Prepare the method for above-mentioned medicine-food two-purpose medlar health preserving cream, comprise the steps, (1) Fructus Lycii of 17 parts, the Rhizoma Polygonati of 0.8 part, the Radix Panacis Quinquefolii of 4 parts, sky essence grass, the Cortex Lycii of 5 parts, the Chinese wolfberry carpopodium of 8 parts, the Radix Glycyrrhizae use water of 0.5 part of 4 parts are cleaned five times, and then soaking 2 ~ 4h, above-mentioned number is mass fraction;

2. sky essence grass, Cortex Lycii, Chinese wolfberry carpopodium, Radix Glycyrrhizae is decocted, the sky essence grass handled well through (1), Cortex Lycii, Chinese wolfberry carpopodium, Radix Glycyrrhizae are inserted in frying pan respectively, the water added in frying pan all exceeds medical material 3 ~ 5cm, first soak 6 ~ 8 hours, then decoct 2 times, each elder generation boils with high heat, with slow fire boiling 2 hours after boiling, filtration obtains medicine juice, before second time decocts, wanting supplementing water to ensure, it is highly constant, filter the medicinal liquid obtained after twice decoction to be incorporated in above-mentioned Fructus Lycii admixing medical solutions, be placed in container and place 6h;

(4) by the medical filtration that upper step process obtains, then pour the heating of frying pan maintenance slow fire into, constantly stir, be stirred to and mention stirring rod medicine juice extension flag, stop heating both to obtain paste.

The clinical case choosing several patient in multiple-case of below comforming is further illustrated medlar health preserving cream effect of the present invention.

(1) Wan Xuehan, sex man, 68 years old age, medical history hypertension history 10 years, cerebral infarction 3 years.

Take 2013-04-16 to 2013 year cream time 07-16, patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

Main clinical manifestation and lab testing contrast during patient consumes, take front main clinical manifestation: dizzy, dizzy, tinnitus, nighttime sleep is poor, mile abnormality when left limb is movable, red tongue, stringy pulse.Have a medical check-up: BP165/100mmhg, heart rate 78 beats/min, two lung (-). left side lower-limb muscular strength 4 grades.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 6.2mmol/L; Triglyceride 5.61mmol/L; T-CHOL 7.8mmol/L; High density lipoprotein 0.85mmol/L; Low density lipoprotein, LDL 4.05mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: take a turn for the better before dizzy, dizzy, tinnitus and sleep comparatively, red tongue, stringy and thready pulse.Fluctuation of blood pressure is detected at about 150-160/90-100mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.8mmol/L; Triglyceride 4.1mmol/L; T-CHOL 6.5mmol/L; High density lipoprotein 0.95mmol/L; Low density lipoprotein, LDL 3.69mmol/L.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.6mmol/L; Triglyceride 2.52mmol/L; T-CHOL 4.6mmol/L; HDL1 .38mmol/L; Low density lipoprotein, LDL 2.63mmol/L.

(2) Zhang Huilan, sex female, 69 years old age, medical history without.

Take 2013-4-09 to 2013 year cream time 07-09, patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.9mmol/L; Triglyceride 1.71mmol/L; T-CHOL 4.35mmol/L; High density lipoprotein 0.78mmol/L; Low density lipoprotein, LDL 1.89mmol/L.To get angry phenomenon without aphtha of the mouth and tongue, scorching etc. in edible medlar health preserving cream process.

(3) Chen Fengxia, sex female, 60 years old age, medical history without.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, tinnitus, hyperhidrosis, susceptible, sleep poor, hectic fever in the afternoon, red tongue, thready and rapid pulse.Have a medical check-up: BP100/60mmhg, heart rate 98 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.7mmol/L; Triglyceride 2.50mmol/L; T-CHOL 5.2mmol/L; HDL1 .02mmol/L; Low density lipoprotein, LDL 3.04mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: dizzy, take a turn for the better before tinnitus and sleep comparatively, sweating takes a turn for the better, and hectic fever in the afternoon takes a turn for the better, red tongue, thready pulse.Fluctuation of blood pressure is detected at about 100-110/70-75mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.5mmol/L; Triglyceride 2.20mmol/L; T-CHOL 4.9mmol/L; High density lipoprotein 0.95mmol/L; Low density lipoprotein, LDL 2.75mmol/L.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.4mmol/L; Triglyceride 1.60mmol/L; T-CHOL 4.5mmol/L; High density lipoprotein 0.95mmol/L; Low density lipoprotein, LDL 2.23mmol/L.Take without any discomfort in medlar health preserving cream process, have no side effect generation.

(4) Ma Chunmei, sex female, 40 years old age, medical history without.

Take 2013-04-05 to 2013 year cream time 07-05, patient per gets after medlar health preserving cream 10ml adds water to 200ml and drinks, every day 1 time.

Main clinical manifestation and lab testing contrast during patient consumes, take front main clinical manifestation: hyperhidrosis susceptible, fatiguability, dim complexion, uneasy sleeping at night, has a dizzy spell, red tongue, white and thin fur, thready pulse without strength.Have a medical check-up: BP100/60mmhg.Heart rate 80 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.7mmol/L; Triglyceride 2.30mmol/L; T-CHOL 4.8mmol/L; High density lipoprotein 0.92mmol/L; Low density lipoprotein, LDL 2.83mmol/L.

Edible medlar health preserving cream one and a half months, main clinical manifestation: having a dizzy spell and sleeping makes moderate progress, spirit is comparatively front to take a turn for the better, and sweating takes a turn for the better, and complexion is comparatively front to take a turn for the better, red tongue, white and thin fur, thready pulse.Have a medical check-up: BP110/70mmhg, heart rate 75 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.5mmol/L; Triglyceride 2.0mmol/L; T-CHOL 4.5mmol/L; High density lipoprotein level 0.89mmol/L; Low density lipoprotein, LDL 2.56mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: tired and sleep obviously improves, and period in a medicine is caught a cold, and sweating is obviously alleviated, and body of the tongue is light red, white and thin fur, thready pulse.Have a medical check-up: BP100/70mmhg, heart rate 78 beats/min, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.0mmol/L; Triglyceride 1.7mmol/L; T-CHOL 4.4mmol/L; High density lipoprotein 0.78mmol/L; Low density lipoprotein, LDL 2.14mmol/L.

(5) buy sky virtue, sex female, 45 years old age, medical history without.

During patient consumes, main clinical manifestation and lab testing contrast, take front main clinical manifestation: dizzy, paroxysmal cardiopalmus, sweating, without uncomfortable in chest, fatiguability, sleeps poor, soreness of the waist and knees, red tongue, deep-thready pulse.Have a medical check-up: BP90/60mmhg, heart rate 88 beats/min, occasional premature beat, two lung (-).

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 5.2mmol/L; Triglyceride 1.10mmol/L; T-CHOL 5.5mmol/L; HDL1 .4mmol/L; Low density lipoprotein, LDL 3.60mmol/L.

Edible medlar health preserving cream 1 first quarter moon, main clinical manifestation: dizzy and feeling of fatigue takes a turn for the better, and soreness of the waist and knees is alleviated, even had palpitation sweating, without uncomfortable in chest, sleep improvement, red tongue, deep-thready pulse.During taking cream, fluctuation of blood pressure is at about 90-100/60-70mmhg.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.8mmol/L; Triglyceride 1.20mmol/L; T-CHOL 4.6mmol/L; HDL1 .21mmol/L; Low density lipoprotein, LDL 2.58mmol/L.

After edible medlar health preserving cream March, main clinical manifestation: dizzy and feeling of fatigue is obviously alleviated, occur without cardiopalmus, sweating obviously improves, sleep improvement, red tongue, stringy pulse.Fluctuation of blood pressure is detected at about 100-110/70-75mmhg during taking cream.

Lab testing: Liver and kidney merit, electrolyte are normal; Blood glucose 4.5mmol/L; Triglyceride 1.20mmol/L; T-CHOL 4.3mmol/L; HDL1 .05mmol/L; Low density lipoprotein, LDL 1.95mmol/L.Generation without any side effects in edible medlar health preserving cream process.

Embodiment six: the medlar health preserving cream of a kind of medicine-food two-purpose that the present invention sends, comprise following raw material, its composition and mass fraction are that Fructus Lycii 12 parts, Rhizoma Polygonati 5 parts, Radix Panacis Quinquefolii 2 part, day essence grass 3 parts, Cortex Lycii 7 parts, Chinese wolfberry carpopodium 2 parts, 3 parts, Radix Glycyrrhizae, preparation method is with embodiment five.

Medlar health preserving paste composition of the present invention is detected, do not detect pesticide composition, the Difenoconazole detected, the amount of Acetamiprid are all less than national standard, belong to safe product, the medlar health preserving cream non agricultural chemical residuum prepared through the inventive method or residual quantity low, good pure natural, pollution-free food

Following table is the testing result of every kg medlar health preserving cream Pesticides,

Test item and unit	Testing result
		Fenpropathrin mg/kg	Do not detect
Prochloraz mg/kg	Do not detect
		Chlopyrifos mg/kg	Do not detect
Pyridaben mg/kg	Do not detect
		Triazophos mg/kg	Do not detect
Difenoconazole mg/kg	0.018
		Metalaxyl mg/kg	Do not detect
Captan mg/kg	Do not detect
		Profenofos mg/kg	Do not detect
Triazolone mg/kg	Do not detect
		Clofentezine mg/kg	Do not detect
Propiconazole mg/kg	Do not detect
		Bravo mg/kg	Do not detect
5a,6,9,9a-hexahydro-6,9-methano-2,4 mg/kg	Do not detect
		Vinclozolin mg/kg	Do not detect
Omethoate mg/kg	Do not detect
		Fenthion mg/kg	Do not detect
Carbofuran mg/kg	Do not detect
		3-hydroxyl carbofuran mg/kg	Do not detect
Bis(4-fluorophenyl)methyl(1H-1,2,4-triazol-1-ylmethyl)silane mg/kg	Do not detect
		Acetamiprid mg/kg	0.522 18 -->
Hexythiazox mg/kg	Do not detect
		Methomyl mg/kg	Do not detect
Imidacloprid mg/kg	Do not detect
		Carbendazim mg/kg	Do not detect
Thiophanate-methyl mg/kg	Do not detect

Be below heavy metal in nutrition in every 100g medlar health preserving cream and every kg medlar health preserving cream, trace element containing scale,

Inspection item and unit	Assay
		Total sugar g/100g	54.6
Total acid g/100g	2.3
		Lycium barbarum polysaccharide g/100g	5.64
Betanin g/100g	0.32
		Flavone g/100g	0.048
Crude protein g/100g	7.20
		Aspartic acid g/100g	1.03
Threonine g/100g	0.14
		Serine g/100g	0.28
Glutamic acid g/100g	0.90
		Proline g/100g	0.78
Glycine g/100g	0.048
		Alanine g/100g	0.32
Cystine g/100g	0.019
		Valine g/100g	0.074
Methionine g/100g	0.011
		Isoleucine g/100g	0.028
Leucine g/100g	0.070
		Tyrosine g/100g	0.023
Phenylalanine g/100g	0.022
		Histidine g/100g	0.18
Lysine g/100g	0.022
		Arginine g/100g	0.088
Total amino acid content g/100g	4.04
		Arsenic mg/kg	0.0096
Plumbous mg/kg	0.074
		Cadmium mg/kg	0.018
Chromium mg/kg	0.26
		Manganese mg/kg	4.58
Zinc mg/kg	7.2
		Copper mg/kg	1.86

This medlar health preserving cream contains the trace element such as aminoacid, zinc in 17 of needed by human as can be seen from the above table, and content of beary metal is also starkly lower than the food limit index of national regulation.

Effect below by way of medlar health preserving cream of the present invention blood fat reducing is described the test of mice: by mice 70, be divided into 7 groups at random, i.e. dosage (0.5g/kg) group, medlar health preserving cream side high dose (1.5g/kg) group in Normal group, hyperlipidemia model group, simvastatin (1.25mg/kg) group, medlar liquid group, medlar health preserving cream side low dosage (0.25g/kg) group, medlar health preserving cream side, often organize 10, male and female half and half.Model control group and Normal group give equal-volume normal saline, and all the other are group gastric infusion respectively respectively, every day 1 time, continuous 10d.After last administration 2h, except Normal group, all the other 5 groups of Intraperitoneal injection fresh egg yolk Emulsion 0.1mL/10g.Pluck eyeball after 20h, get blood, before getting blood, water is can't help in 12h fasting, measures mice serum TC, TG, HDL-C, LDL-C,

Below the impact of medlar health preserving cream on induced Hyperlipidemia in Mice,

Group	Dosage	TC	TG	HDL-C	LDLC
						Normal saline group	0.4ml	3.1995±0.4333	1.8459±0.3712	2.6300±0.3483	0.9249±0.3821
Model group	0.4ml	4.5423±0.5133△△	2.5703±0.4497△△	2.2173±0.1115△	2.0330±0.6838△△
						Simvastatin	1.25mg/kg	3.2322±0.7245**	1.9566±0.4778**	2.7731±0.2179**	1.1656±0.9225*
Fructus Lycii group	1.5g/kg	4.1787±1.0186	2.2537±0.5416	2.8880±0.4807**	1.5788±1.2126
						Medlar health preserving cream is high	1.5g/kg	3.7012±0.5124*	1.9350±0.2780**	2.9407±0.6246**	1.0451±0.2332**
In medlar health preserving cream	0.5g/kg	3.9207±0.3668	1.8321±0.4010**	3.1926±0.5091**	1.5913±0.4082
						Medlar health preserving cream is low	0.25g/kg	4.4488±0.9777	2.3658±0.6505	2.7274±0.3634*	1.4939±0.6667

Remarks: with normal saline group than △ p<0.05; △ △ p<0.01; With model group than * p<0.05; * p<0.01.

Result: model group mice serum TC, TG, LDL-C content comparatively normal saline group obviously raises (P<0.01), Serum HDL-C serum content comparatively normal saline group reduces (P<0.05); Medlar health preserving cream 1.5g/ (kgd) dosage group mice serum TC, TG, LDL-C content has reduction (P<0.05 or P<0.01) in various degree compared with model group, and Serum HDL-C serum content obviously raises (P<0.01); Medlar health preserving cream 0.5g/ (kgd) dosage group serum TC, the LDL-C comparatively above index of model group are showed no difference, only have serum TG obviously to reduce (P<0.01), Serum HDL-C serum content obviously raises (P<0.01); Medlar health preserving cream 0.25g/ (kgd) dosage group serum TC, TG, LDL-C comparatively above index of model group are showed no difference, and only Serum HDL-C serum content raises (P<0.05).

Conclusion: medlar health preserving cream can reduction model group with hyperlipemia mice serum T-CHOL (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) in various degree, the content of high density lipoprotein increasing cholesterol (HDL-C).

Medlar health preserving cream is eaten to mice and carries out oxygen deficit tolerance test:

Get mice 60, be divided into 6 groups at random, often organize 10, be respectively saline control group (NS), medlar liquid, Radix Ginseng decocting liquid group, oral liquid high (YQD), in (YQZ), low (YQX) dosage group, the continuous gavage 10d of mice.After last administration 30min (operation repetitive), put into the 150mL port grinding bottle (1 every bottle) filling 15g sodica calx, seal, bottleneck is coated with vaseline, with respiratory arrest for dead indication, record envelope bottleneck is the time-to-live to the time that mouse breathing stops, and calculates the survival time under hypoxic condition prolongation percentage rate=(administration group the survival time under hypoxic condition-normal group the survival time under hypoxic condition)/normal group the survival time under hypoxic condition × 100

The results are shown in following table,

Group	Dosage (g/kg)	Time-to-live (dividing)	Prolonged survival period percentage rate (%)
				Normal saline group		25.02±5.418
Ginseng decoction group	1	32.76±8.365*	30.9
				Medlar liquid group	1.5	33.16±6.726*	32.5
Medlar health preserving cream is high	5	34.52±6.985*	37.9
				In medlar health preserving cream	2.5	32.96±8.042*	31.7 20 -->
Medlar health preserving cream is low	1.25	29.71±11.56	18.7

Remarks: compare * p<0.05 with normal saline group; * p<0.01.

Oxygen deficit tolerance is anoxia is a kind of stressor, and body can be caused to produce the reaction of various irritability, and vital movement midbrain and myocardial ischemia are mice normobaric hypoxia main causes of death.

Result: experimental result shows, the medlar health preserving cream of various dose all can the time-to-live of prolongation mice under airtight anoxia condition in various degree, improves heart and brain hypoxia-bearing capability, reduce Tissue oxygen consumption.The time-to-live of medlar health preserving cream 1.25 ~ 5g/ (kgd) dosage group compares with normal saline group; difference significance; wherein organize the time-to-live with 5g/ (kgd) the longest, reach (34.52 ± 6.985) min, be better than other each dosage group; The effect of 2.5g/ (kgd) dosage group is taken second place.Increase mouse survival time lengthening rate with medlar health preserving unguentum amount rises gradually, and when medlar health preserving cream 5g/ (kgd) dosage, rate elongation maximum (37.9%), is better than other each dosage group; The effect of 2.5g/ (kgd) dosage group is taken second place.

Conclusion: medlar health preserving cream has the function improving laboratory animal hypoxia-bearing capability.

Below medlar health preserving cream is taken by anti-fatigue effect being described to Loaned swimming test to mice:

Get mice 60, be divided into 6 groups at random, often organize 10, be respectively saline control group (NS), Radix Ginseng decocting liquid group, oral liquid high (YQD), in (YQZ), low (YQX) dosage group,, the continuous gavage 10d of mice.After last administration 60min (operation repetitive), then carry out swimming test.Mouse tail heavy burden 1g, bucket (control water depth 25cm, water temperature is at 25 ~ 27 DEG C) swimming in 60cm diameter exhausts death to power.The impact of medlar health preserving cream side on the mice burden swimming time sees the following form,

Group	Dosage (g/kg)	Swimming time (dividing)	Extend percentage rate (%)
				Normal saline group		26.1±14.5
Ginseng decoction group	1	46.1±22.6	76.6
				Medlar health preserving cream is high	5	72.1±25.4	176.2
In medlar health preserving cream	2.5	68.5±37.2	162.5
				Medlar health preserving cream is low	1.25	48.6±36.1	86.2

Swimming with a load attached to the body experiment is that namely sports fatigue refers to can not continue its function on a specified level and (or) can not maintain the phenomenon of body movement ability decline of predetermined exercise intensity by the organism physiology process that body movement itself is caused.Its evaluation methodology mainly contains 2 kinds: exercise tolerance test and detection cause the change of tired biochemical indicator.The time that power exhausts measures body persistent movement until can react the endurance of body, exercise tolerance is reflection organism fatigue index the most intuitively, this experimental selection Loaned swimming test of mice, just result in the generation of tired sensation during motion just because of biochemical change, 4 biochemical indicators that therefore during the motion of this experimental selection, change is obvious, its intensity of variation is consistent with sports load and intensity are as the evaluation index of resisting fatigue.

Result: experimental result shows; the medlar health preserving cream of various dose all can prolongation mice burden swimming time in various degree; medlar health preserving cream 1.25 ~ 5g/ (kgd) the dosage group mice burden swimming time compares with normal saline group; difference significance; wherein organize the mice burden swimming time with 5g/ (kgd) the longest; reach (72.1 ± 25.4) min, be better than other each dosage group; The effect of 2.5g/ (kgd) dosage group is taken second place.Increase mice burden swimming time lengthening rate with medlar health preserving unguentum amount rises gradually, and when medlar health preserving cream 5g/ (kgd) dosage, rate elongation maximum (176.2%), is better than other each dosage group; The effect of 2.5g/ (kgd) dosage group is taken second place.

Conclusion: medlar health preserving cream has the effect of the walking weight load extending mice, improves anti-fatigue ability.

Any restriction of technique scheme not to technical scheme, those skilled in the art all embody principle of the present invention to some variations that wherein some part may be made, and belong within protection scope of the present invention.

Claims

1. prepare a method for medicine-food two-purpose medlar health preserving cream, it is characterized in that, comprise the steps:

(1) Fructus Lycii of 8 ~ 20 parts, the Rhizoma Polygonati of 0.5 ~ 6 part, the Radix Panacis Quinquefolii of 0.5 ~ 8 part, the sky essence grass of 0.5 ~ 5 part, the Cortex Lycii of 1 ~ 10 part, 0.5 ~ 8 part of Chinese wolfberry carpopodium, the Radix Glycyrrhizae use water of 0.5 ~ 5 part are cleaned five times, and then soaking 2 ~ 4h, above-mentioned number is mass fraction;

2. Cortex Lycii, sky essence grass, Chinese wolfberry carpopodium, Radix Glycyrrhizae is decocted: the smart grass in the Cortex Lycii handled well through step (1), sky, Chinese wolfberry carpopodium, Radix Glycyrrhizae are inserted in frying pan respectively, the water added in each frying pan all exceeds medical material 3 ~ 5cm, first soak 6 ~ 8 hours, then decoct 2 times, each elder generation boils with high heat, with slow fire boiling 2 hours after boiling, filtration obtains medicine juice, before second time decocts, wanting supplementing water to ensure, it is highly constant, filter the medicinal liquid obtained after twice decoction to be incorporated in above-mentioned Fructus Lycii admixing medical solutions, be placed in container and place 6h;

(4) by the medical filtration that upper step process obtains, then pour the heating of frying pan maintenance slow fire into, and constantly stir, be stirred to and mention stirring rod medicine juice extension flag, stop heating namely obtaining the medlar oil of medicine-food two-purpose.

2. the method preparing medicine-food two-purpose medlar health preserving cream according to claim 1, it is characterized in that, after described step (4) obtains medlar health preserving cream, spend when also not leaving while hot, pour into fast and to have cleaned and in the container of sterilizing, Temperature fall at ambient temperature, until medlar health preserving cream temperature is cool to room temperature, row capping is preserved again, and the temperature of preservation is 2 ~ 8 DEG C.