CN103393804A

CN103393804A - Medicine for treating postpartum hypogalactia and preparation method thereof

Info

Publication number: CN103393804A
Application number: CN2013103183508A
Authority: CN
Inventors: 张佳奇
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-07-26
Filing date: 2013-07-26
Publication date: 2013-11-20

Abstract

The invention discloses a medicine for treating postpartum hypogalactia and a preparation method thereof. The medicine is mainly prepared by bighead atractylodes rhizome, astragali radix, ginseng, angelica sinensis, the seed of cowherb, and poria cocos according to a certain weight ratio. The medicine provided in the invention can induce diuresis to alleviate edema, promote circulation of blood and stimulate the menstrual flow, and hasten parturition and promote lactation, and is rapid and favorable in curative effect, and high in curative ratio.

Description

A kind of medicine for the treatment of puerperal hypogalactia and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of puerperal hypogalactia and preparation method thereof, belong to the field of Chinese medicines.

Technical background

The puerpera when suckling milk very less or completely without, enough even can the feeding infant person, be called puerperal hypogalactia.Degree and the situation of hypogalactia are different: during the beginning suckling that has, lack, and later slightly many but still inadequate; Have completely without milk, can not feed breast fully; The normal suckling that has, after high heat or morbidity, milk is suddenly few, is not enough to feeding infant suddenly.At present, western medicine puerperal hypogalactia poor effect, and more side effect is arranged, therefore, there is very large demand in people to the Chinese medicine of rapid, effective treatment puerperal hypogalactia.

Summary of the invention

The inventor, according to the research of theory of Chinese medical science and clinical repeatedly test and checking, has finally found the medicine of rapid, effective treatment puerperal hypogalactia, thereby has completed the present invention.

Purpose of the present invention just is to provide a kind of composition of medicine that can the rapid, effective treatment puerperal hypogalactia.

Another object of the present invention just has been to provide the preparation method of this composition of medicine.

Medicine of the present invention selects the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Radix Ginseng, Radix Angelicae Sinensis, Semen Vaccariae, Poria, Radix Glycyrrhizae, Rhizoma Chuanxiong, Fructus Aurantii, Radix Pseudostellariae, Medulla Tetrapanacis medicine to make up, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can the rapid, effective treatment puerperal hypogalactia.Wherein selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature, enter spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension, have loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.Select the Radix Astragali to be because its nature and flavor are sweet, tepor, enter lung, spleen channel, give birth to the useful consolidating superficial resistance of defending, and inducing diuresis to remove edema, poison holding, the function of granulation promoting, control spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and hold back for a long time; Process with the function that the invigorating middle warmer benefit is arranged, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Radix Ginseng to be because its nature and flavor are sweet micro-sweet, temperature, enter spleen, lung meridian, and strongly invigorating primordial QI is arranged, admittedly take off, promote the production of body fluid, the function of calming the nerves, control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, the stool lingering diarrhea, empty cough with asthma is short, the spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm enters the heart, liver, spleen channel, benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Semen Vaccariae to be because its nature and flavor are bitter flat, enter liver, stomach warp, have promoting the circulation of blood to stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, the function of detumescence sore, control women's amenorrhea, galactostasis, and difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.Select Poria to be because its property slightly sweet flavor is flat, enter the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach lack of appetite, stomachache loose stool, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle, give birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separate poison of drug and alimentary toxicosis.Selecting Rhizoma Chuanxiong is because its nature and flavor suffering, and temperature, enter liver, gallbladder meridian, and activating QI to alleviate the depression is arranged, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Selecting Fructus Aurantii is because its nature and flavor toil, cool, enters lung, spleen, large intestine channel, and dispelling the stagnated QI is arranged, row expectorant, the function of removing food stagnancy, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery, proctoptosis, uterine prolapse.Selecting Radix Pseudostellariae is that tepor, enter the heart, spleen, lung three warps, and the function of tonifying the lung, spleen invigorating is arranged, and controls the cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Medulla Tetrapanacis to be because its property slightly sweet flavor is cool, enter lung, stomach warp, eliminating the pathogens from the lung is arranged, diuresis, the function of lower milk, control dysuria, gonorrhea, edema, puerpera's galactostasis, blurred vision, nasal obstruction.

The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope

The Rhizoma Atractylodis Macrocephalae 8-15 gram Radix Astragali 8-15 gram Radix Ginseng 5-10 grams

Radix Angelicae Sinensis 10-20 gram Semen Vaccariae 10-20 gram Poria 15-25 grams

Radix Glycyrrhizae 6-10 gram Rhizoma Chuanxiong 15-25 gram Fructus Aurantii 15-25 grams

Radix Pseudostellariae 6-10 gram Medulla Tetrapanacis 15-25 grams

Preferable amount is

The Rhizoma Atractylodis Macrocephalae 10 gram Radix Astragali 10 gram Radix Ginseng 6 grams

Radix Angelicae Sinensis 15 gram Semen Vaccariae 15 gram Poria 20 grams

Radix Glycyrrhizae 8 gram Rhizoma Chuanxiong 20 gram Fructus Aurantii 20 grams

Radix Pseudostellariae 8 gram Medulla Tetrapanacis 20 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, after bubble, pull out, run through, section, dry;

2, the Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;

3, Radix Ginseng: except removing LU, cutting is dried;

4, Radix Angelicae Sinensis: choose decontamination, clean, moistening, slightly dry in the air when suitable to inside and outside humidity, and section is dried;

5, Semen Vaccariae: the clean impurity of winnowing with a dustpan, put in pot, while with the slow fire stir-fry, to popping, spending six, seventy percent in vain, take out, cool;

6, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

7, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly the time to eighty per cant, run through section, airing;

8, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, after moistening, cuts into slices, and drying;

9, Fructus Aurantii: remove flesh, core, edulcoration, slightly soak, and pulls out, moisten soft, the section, dry;

10, Radix Pseudostellariae: extract fibrous root, dry;

11, Medulla Tetrapanacis: choose decontamination, section.

Two, preparation

1, the Rhizoma Atractylodis Macrocephalae of described weight, the Radix Astragali, Radix Ginseng, Radix Angelicae Sinensis, Semen Vaccariae, Poria, Radix Glycyrrhizae, Rhizoma Chuanxiong, Fructus Aurantii, Radix Pseudostellariae, Medulla Tetrapanacis medicine are decocted with water to secondary, add for the first time 6 times of amounts of water, soak after 160 minutes, intense fire decocts boiling 10 minutes, used again slow fire boiling 20 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.

2, the medicinal residues of filtration are added to 4 times of amounts of water, boil with high heat, then used slow fire boiling 15 minutes, filter to obtain decoction liquor for the second time.

3, twice decoction liquor merged and stir, be divided into 4 doses and take.

Medicine of the present invention has activating QI to alleviate the depression, inducing diuresis to remove edema, and promoting the circulation of blood is stimulated the menstrual flow, and expedites the emergence of the function of stimulating milk secretion, is used for the treatment of puerperal hypogalactia, short treating period, instant effect, non-relapse after healing, has no side effect.

The specific embodiment

Below by test example, further set forth the beneficial effect of medicine of the present invention, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, every day 2 times, serve on 7 days, observes the administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] Drug therapy puerperal hypogalactia of the present invention

1, physical data

Accept out-patient's totally 350 examples for medical treatment.

2, diagnostic criteria

" puerperal hypogalactia " mostly occurs 2-3 days puerperal to two weeks.Check breast and milk character, can assist diagnosis.The milk that must cause with crater nipple and cracked nipple is clinically stopped up long-pending obstructed, and dysilthia is differentiated mutually.During nursing baby in lactation period for puerpera agalactosis or completely without, even be not enough to can not feeding infant, be main bases.Puerperal, milk was very less or completely without being called " puerperal hypogalactia ".

3, Therapeutic Method

Select above-mentioned medicament, to the patient, take, each serving with 1 dose, every day early, respectively take 1 evening, and 5 days is a course for the treatment of, takes continuously 4 courses for the treatment of.

4, efficacy assessment standard

Produce effects: after medication treatment, milk is supplied with normal, can meet baby's normal nursing;

Take a turn for the better: by agalactia, transfer to breast is arranged, but milk still can not meet baby's demand;

Invalid: as not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, with Drug therapy puerperal hypogalactia patient of the present invention 350 examples, produce effects 335 examples as a result, obvious effective rate is 95.71%, 10 examples that take a turn for the better, improvement rate is 2.86%, invalid 5 examples, total effective rate is 98.57%.

Claims

1. medicine for the treatment of puerperal hypogalactia, it is characterized in that: it is to be made by the crude drug in following weight range:

Radix Pseudostellariae 6-10 gram Medulla Tetrapanacis 15-25 grams.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Radix Angelicae Sinensis 15 gram Semen Vaccariae 15 gram Poria 20 grams

Radix Glycyrrhizae 8 gram Rhizoma Chuanxiong 20 gram Fructus Aurantii 20 grams

Radix Pseudostellariae 8 gram Medulla Tetrapanacis 20 grams.

3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:

(1) get the raw materials ready

(1) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, after bubble, pull out, run through, section, dry;

(2) Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;

(3) Radix Ginseng: except removing LU, cutting is dried;

(4) Radix Angelicae Sinensis: choose decontamination, clean, moistening, slightly dry in the air when suitable to inside and outside humidity, and section is dried;

(5) Semen Vaccariae: the clean impurity of winnowing with a dustpan, put in pot, while with the slow fire stir-fry, to popping, spending six, seventy percent in vain, take out, cool;

(6) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

(7) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly the time to eighty per cant, run through section, airing;

(8) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, after moistening, cuts into slices, and drying;

(9) Fructus Aurantii: remove flesh, core, edulcoration, slightly soak, and pulls out, moisten soft, the section, dry;

(10) Radix Pseudostellariae: extract fibrous root, dry;

(11) Medulla Tetrapanacis: choose decontamination, section;

(2) preparation

(1) Rhizoma Atractylodis Macrocephalae of described weight, the Radix Astragali, Radix Ginseng, Radix Angelicae Sinensis, Semen Vaccariae, Poria, Radix Glycyrrhizae, Rhizoma Chuanxiong, Fructus Aurantii, Radix Pseudostellariae, Medulla Tetrapanacis medicine are decocted with water to secondary, add for the first time 6 times of amounts of water, soak after 160 minutes, intense fire decocts boiling 10 minutes, used again slow fire boiling 20 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time;

(2) medicinal residues of filtration are added to 4 times of amounts of water, boil with high heat, then used slow fire boiling 15 minutes, filter to obtain decoction liquor for the second time;

(3) twice decoction liquor merged and stir, be divided into 4 doses and take.