CN103349700A - Medicine for treating haemorrhoids and preparation method of medicine - Google Patents
Medicine for treating haemorrhoids and preparation method of medicine Download PDFInfo
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- CN103349700A CN103349700A CN2013103205348A CN201310320534A CN103349700A CN 103349700 A CN103349700 A CN 103349700A CN 2013103205348 A CN2013103205348 A CN 2013103205348A CN 201310320534 A CN201310320534 A CN 201310320534A CN 103349700 A CN103349700 A CN 103349700A
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Abstract
The invention discloses medicine for treating haemorrhoids and a preparation method of the medicine. The medicine is prepared by the following ingredients by certain weight percentage: rhizoma atractylodis, rhizoma atractylodis macrocephalae, rhubarb, cortex phellodendri, radix gentianae macrophyllae and radix saposhnikoviae. The medicine has functions of yin nourishing, fire lowering, dryness moistening, laxation, toxic heat discharging, indigestion breaking, and blood stasis resolving, and is fast and good in effect, and high in cure rate when used for treating the hemorrhoids.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hemorrhoid and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Hemorrhoid are a kind of chronic diseases of the vein group of the venous plexus generation varicose of anal orifice and rectal intestine bottom and anal mucosa and one or more softnesses of forming.Usually continue to exert oneself when defecation, cause herein that intravenous pressure raises repeatedly, vein will enlargement.The women, hindered blood circulation and often hemorrhoid can occur because pelvic cavity suffers oppression in trimester of pregnancy, and the people of many obesities also can suffer from hemorrhoid.At present, western medicine hemorrhoid poor effect, and more side effect is arranged, therefore, there is very large demand in people to the Chinese medicine of effective treatment hemorrhoid.
Summary of the invention
The inventor has finally found the medicine of effective treatment hemorrhoid, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.
Purpose of the present invention just provides a kind of composition of medicine that can effectively treat hemorrhoid.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicine of the present invention selects Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Sinensis, Semen Persicae, Fructus Aurantii Immaturus, Radix Sanguisorbae, Herba Euphorbiae Helioscopiae, Spina Gleditsiae medicine to make up, with these drug regimens so that each efficacy of drugs produces synergism, thereby can effectively treat the recurrence of hemorrhoid.Wherein select Rhizoma Atractylodis to be because its nature and flavor are arduous, temperature enters spleen, stomach warp, and spleen invigorating is arranged, dampness, and resolving depression is warded off dirty function, control wet the Sheng and be stranded spleen, the asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, dysentery is had loose bowels in vomiting, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature enters spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.Select Radix Et Rhizoma Rhei to be because its nature and flavor are bitter, cold, enter stomach, large intestine, liver footpath, the poison of purging heat is arranged, removing mass stagnates, the function of clots absorbing blood is controlled the excess-heat constipation, and delirium is gone mad, the food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, the time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia is spitted blood epistaxis, YANG jaundice, edema, stranguria with turbid discharge is urinated red, the carbuncle and ulcer toxic swelling, furuncle, burn.Select Cortex Phellodendri to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, nourishing YIN to lower pathogenic fire is arranged, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Radix Gentianae Macrophyllae to be because its nature and flavor toil is flat, enter liver, stomach, gallbladder meridian, expelling wind and removing dampness is arranged, and the blood Shujin, the function of clearing away heat and promoting diuresis, the dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture, jaundice is had blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Selecting Radix Saposhnikoviae is that temperature enters bladder, lung, spleen channel, delivers because of its property acrid-sweet flavor, dispels the wind, and wins and wets, and the function of pain relieving is controlled affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, and anemofrigid-damp arthralgia, joint is ached, and the extremity contraction is anxious, tetanus.Selecting Radix Angelicae Sinensis is that temperature enters the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after the bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Semen Persicae to be because its property bitter but sweet flavor is flat, enter the heart, liver, large intestine channel, blood stasis removing and clots absorbing is arranged, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select Fructus Aurantii Immaturus to be because its nature and flavor are bitter, cold, enter spleen, stomach warp, dispelling the stagnated QI is arranged, loose painful abdominal mass is rushed down expectorant, and the function of removing food stagnancy is controlled chest and abdomen swelling and pain, the thoracic obstruction, painful abdominal mass pain, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis.Select Radix Sanguisorbae to be because its nature and flavor picric acid, cold.Enter liver, large intestine channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, collapse, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.Select Herba Euphorbiae Helioscopiae to be because its nature and flavor are arduous, cold, poisonous, enter large and small intestinal, spleen has capable water, expectorant, parasite killing, the function of detoxifcation is controlled edematous asthma, and phlegm retention is breathed with cough, malaria, scrofula, tinea skin ulcer, Tuberculous flaccidity pipe, osteomyelitis.Select Spina Gleditsiae to be because its nature and flavor are hot, temperature is searched wind, draw out pus by applying a plaster to the affected part, and detumescence, the function of evacuation of pus is controlled carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.
The drug dose of the present invention's combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope
Rhizoma Atractylodis 10-20 gram Rhizoma Atractylodis Macrocephalae 10-20 gram Radix Et Rhizoma Rhei 10-20 gram
Cortex Phellodendri 10-20 gram Radix Gentianae Macrophyllae 10-20 gram Radix Saposhnikoviae 10-20 gram
Radix Angelicae Sinensis 10-20 gram Semen Persicae 10-20 gram Fructus Aurantii Immaturus 10-20 gram
Radix Sanguisorbae 10-20 gram Herba Euphorbiae Helioscopiae 10-20 gram Spina Gleditsiae 10-20 gram
Preferable amount is
The Rhizoma Atractylodis 15 gram Rhizoma Atractylodis Macrocephalaes 15 gram Radix Et Rhizoma Rhei 15 grams
Cortex Phellodendri 15 gram Radix Gentianae Macrophyllae 15 gram Radix Saposhnikoviaes 15 grams
Radix Angelicae Sinensis 15 gram Semen Persicaes 15 gram Fructus Aurantii Immaturuss 15 grams
Radix Sanguisorbae 15 gram Herba Euphorbiae Helioscopiae 15 gram Spina Gleditsiaes 15 grams
The preparation method of medicine of the present invention is as follows
One, gets the raw materials ready
1, Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;
2, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;
3, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;
4, Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding are dried;
5, Radix Gentianae Macrophyllae: choose decontamination, except removing LU, slightly soak, run through section, dry;
6, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
7, Radix Angelicae Sinensis: choose decontamination, clean, run through, section is dried;
8, Semen Persicae: remove duricrust impurity, put and boil in the boiling water pot to the little wrinkle of crust, pull out, immerse in the cold water, rub with the hands and remove kind of a skin, dry, winnow with a dustpan clean;
9, Fructus Aurantii Immaturus: choose clean impurity, be soaked in water to eighty per cant saturating, pull out, profit is to interior without hard-core, and section is dried;
10, Radix Sanguisorbae: choose decontamination, wash, slightly soak, run through, be cut into sheet, dry;
11, Herba Euphorbiae Helioscopiae: get crude drug, remove undesirable root, impurity is cleaned, and slightly moistens cutting, drying;
12, Spina Gleditsiae: choose decontamination, be soaked in water, run through rear section, dry.
Two, preparation
1, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Sinensis, Semen Persicae, Fructus Aurantii Immaturus, Radix Sanguisorbae, Herba Euphorbiae Helioscopiae, the Spina Gleditsiae medicine with described weight decocts with water secondary, add for the first time 8 times of water gagings, soak after 200 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 20 minutes, and filtered to get decoction liquor for the first time.
2, the medicinal residues that filter are added 4 times of amounts of water, intense fire decocts boiling, uses slow fire boiling 20 minutes again, filters to get decoction liquor for the second time.
3, twice decoction liquor merged, simmered in water again 10 minutes, get medicinal liquid, medicinal liquid is divided into 3 doses takes.
Medicine of the present invention has nourishing YIN to lower pathogenic fire, moisturizes laxation, and the poison that purges heat, removing mass stagnate, and the effect of clots absorbing blood is used for the treatment of hemorrhoid, short treating period, instant effect, non-relapse after healing, has no side effect.
The specific embodiment
Below further set forth the beneficial effect of medicine of the present invention by test example, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg divides two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, serve on 7 days every day twice, observes the administration reaction every day, and the result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] Drug therapy hemorrhoid of the present invention
1, physical data
Accept out-patient's totally 300 examples for medical treatment, its male patient's 160 examples, female patient 140 examples.
2, diagnostic criteria
Symptom one, the stool hemorrhage: it is its characteristics that Silent Neuritis, intermittence have cerise blood after an action of the bowels, also is the early stage common sympton of internal hemorrhoid or mixed hemorrhoid.Before hemorrhage generally occur in just or after an action of the bowels, simple having blood in stool arranged, also can mix with stool and descend.Color is scarlet, is spurting, drop shape, wiper cord blood etc. when it is hemorrhage.
Symptom two, dyschizia: occur crissum pain phenomenon during stool.Because the nervous system of crissum is relatively more flourishing and sharp, be easy to occur pain after being upset.Generally show as mild pain, twinge, causalgia, distending pain etc.
Symptom three, rectum pendant pain: anal orifice and rectal intestine pendant pain mainly is the symptom of external hemorrhoid.If internal hemorrhoid is infected, incarceration, strangulation to occur downright bad, can cause so violent pendant pain.The lighter has the distension bearing down, and misery then can appear heavily falling in severe one.
Symptom four, swollen thing are deviate from: the inner thing that occurs swelling of anus is deviate from, and this mainly is the symptom of middle and advanced stage internal hemorrhoid.Along with the continuous increase of internal hemorrhoid blood stasis, mucosa and tela submucosa are separated with the anus layer, during defecation, the internal hemorrhoid tuberosity can drop to below the pectinate line, is free on outside the anal canal, and per anum is deviate from.The lighter only just can deviate from when defecation outside the anus, and severe one is being coughed, presses abdomen, can deviate from when firmly squatting down.
Symptom five, flow point secretion: anus flows out secretions.Mainly overflowed by the fistula mouth, also can be discharged by anal, or overflowed by the skin of crissum.Rectal mucosa is subjected to the stimulation of hemorrhoid for a long time, causes secretions increase; Late period, internal hemorrhoid because of Sphincter ani chalasia, often had secretions to be flowed out by anus.Flow out when the lighter defecates, severe one does not flow out during defecation naturally yet.
Symptom six, pruritus ani: the hemorrhage pruritus symptom of anus and crissum skin.Mainly be that skin is moist all day, thereby produces scratchiness, causes the generation of eczema and pruritus owing to anus secretions, deviating from blood stasis and surrounding skin has been subject to stimulation.
3, Therapeutic Method
Select above-mentioned medicament, take to the patient, each serving with 1 dose, every day early, middle and late respectively the clothes 1 time, 7 days is a course for the treatment of, takes continuously 6 courses for the treatment of.
4, efficacy assessment standard
Produce effects: hemorrhoid symptom disappears, and it is normal that body constitution is recovered, and observes half a year without the recidivist;
Take a turn for the better: hemorrhoid symptom is clearly better, and body constitution is progressively recovered;
Invalid: as not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, with Drug therapy hemorrhoid patients 300 examples of the present invention, produce effects 290 examples as a result, obvious effective rate is 96.67%, 6 examples that take a turn for the better, improvement rate is 2%, invalid 4 examples, total effective rate is 98.67%.
Claims (3)
1. medicine for the treatment of hemorrhoid, it is characterized in that: it is to be made by the crude drug in the following weight range:
Rhizoma Atractylodis 10-20 gram Rhizoma Atractylodis Macrocephalae 10-20 gram Radix Et Rhizoma Rhei 10-20 gram
Cortex Phellodendri 10-20 gram Radix Gentianae Macrophyllae 10-20 gram Radix Saposhnikoviae 10-20 gram
Radix Angelicae Sinensis 10-20 gram Semen Persicae 10-20 gram Fructus Aurantii Immaturus 10-20 gram
Radix Sanguisorbae 10-20 gram Herba Euphorbiae Helioscopiae 10-20 gram Spina Gleditsiae 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The Rhizoma Atractylodis 15 gram Rhizoma Atractylodis Macrocephalaes 15 gram Radix Et Rhizoma Rhei 15 grams
Cortex Phellodendri 15 gram Radix Gentianae Macrophyllae 15 gram Radix Saposhnikoviaes 15 grams
Radix Angelicae Sinensis 15 gram Semen Persicaes 15 gram Fructus Aurantii Immaturuss 15 grams
Radix Sanguisorbae 15 gram Herba Euphorbiae Helioscopiae 15 gram Spina Gleditsiaes 15 grams.
3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:
(1) gets the raw materials ready
(1) Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;
(2) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;
(3) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;
(4) Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding are dried;
(5) Radix Gentianae Macrophyllae: choose decontamination, except removing LU, slightly soak, run through section, dry;
(6) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(7) Radix Angelicae Sinensis: choose decontamination, clean, run through, section is dried;
(8) Semen Persicae: remove duricrust impurity, put and boil in the boiling water pot to the little wrinkle of crust, pull out, immerse in the cold water, rub with the hands and remove kind of a skin, dry, winnow with a dustpan clean;
(9) Fructus Aurantii Immaturus: choose clean impurity, be soaked in water to eighty per cant saturating, pull out, profit is to interior without hard-core, and section is dried;
(10) Radix Sanguisorbae: choose decontamination, wash, slightly soak, run through, be cut into sheet, dry;
(11) Herba Euphorbiae Helioscopiae: get crude drug, remove undesirable root, impurity is cleaned, and slightly moistens cutting, drying;
(12) Spina Gleditsiae: choose decontamination, be soaked in water, run through rear section, dry;
(2) preparation
(1) Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Radix Angelicae Sinensis, Semen Persicae, Fructus Aurantii Immaturus, Radix Sanguisorbae, Herba Euphorbiae Helioscopiae, the Spina Gleditsiae medicine with described weight decocts with water secondary, add for the first time 8 times of water gagings, soak after 200 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 20 minutes, and filtered to get decoction liquor for the first time;
(2) medicinal residues that filter are added 4 times of amounts of water, intense fire decocts boiling, uses slow fire boiling 20 minutes again, filters to get decoction liquor for the second time;
(3) twice decoction liquor merged, simmered in water again 10 minutes, get medicinal liquid, medicinal liquid is divided into 3 doses takes.
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| CN101129677A (en) * | 2007-09-14 | 2008-02-27 | 景午辰 | Quick-effective pill for hemorrhoid |
| CN101979031A (en) * | 2010-10-28 | 2011-02-23 | 李桂宾 | Medicament for treating hemorrhoids and preparation method thereof |
| CN102772711A (en) * | 2012-08-21 | 2012-11-14 | 杨兰英 | Medicament for treating haemorrhoids and preparation method thereof |
| CN102772553A (en) * | 2012-07-31 | 2012-11-14 | 王之渊 | Medicine for treating haemorrhoids and preparation method thereof |
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2013
- 2013-07-29 CN CN2013103205348A patent/CN103349700A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1768831A (en) * | 2004-11-05 | 2006-05-10 | 兰州佛光制药有限公司 | Medicine for treating piles and its preparing process |
| CN1969884A (en) * | 2005-11-25 | 2007-05-30 | 胡开平 | Medicament for treating piles |
| CN101129677A (en) * | 2007-09-14 | 2008-02-27 | 景午辰 | Quick-effective pill for hemorrhoid |
| CN101979031A (en) * | 2010-10-28 | 2011-02-23 | 李桂宾 | Medicament for treating hemorrhoids and preparation method thereof |
| CN102772553A (en) * | 2012-07-31 | 2012-11-14 | 王之渊 | Medicine for treating haemorrhoids and preparation method thereof |
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Non-Patent Citations (2)
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| 汪昂（清）: "《汤头歌诀》", 30 April 2010, 北方妇女儿童出版社 * |
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Application publication date: 20131016 |