CN104127831A - Traditional Chinese medicine for treating pantalgia after childbirth caused by exogenous pathogen and preparation method thereof - Google Patents

Traditional Chinese medicine for treating pantalgia after childbirth caused by exogenous pathogen and preparation method thereof Download PDF

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CN104127831A
CN104127831A CN201410416060.1A CN201410416060A CN104127831A CN 104127831 A CN104127831 A CN 104127831A CN 201410416060 A CN201410416060 A CN 201410416060A CN 104127831 A CN104127831 A CN 104127831A
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radix
rhizoma
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caulis
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张梅
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Abstract

The invention discloses a traditional Chinese medicine for treating pantalgia after childbirth caused by exogenous pathogen and a preparation method thereof. The traditional Chinese medicine comprises the following raw herbal materials: schizonepeta, notopterygium root, Chinese parsnip root, radix angelicae, radices ligustici sinensis, fistular onion stalk, tamarix chinensis, lycopodium clavatum, berba aristolochiae mollissimae, caulis sinomenii, morinda officinalis, fructus liquidambaris, Chinese starjasmine stem, suberect spatholobus stem, flowers carthami, ligusticum wallichii, rhizoma corydalis, turmeric, cowherb seed, codonopsis pilosula, astragalus membranaceus, Chinese yam, liquorice, rhodiola rosea, short-pedicel aconite root, common fenugreek seed, taxillus chinensis danser, stachys sieboldii, erythrina indica lam, deer-horn glue and chestnut. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicine has the efficacies of nourishing the blood to expel wind, and dispelling cold and removing dampness, syndrome differentiation and treatment is carried out on the basis of the whole view of organism, natural green medicinal materials are selected, the pharmacological effect is through to a focus of infection, and the traditional Chinese medicine is short in treatment course, good in curative effect, small in toxic and side effects, free of an untoward effect, low in cost, and simple in preparation process, also can play a certain health effect on the organism when the pantalgia after childbirth is treated, and can be clinically popularized to meet the clinical treatment requirements of the pantalgia after childbirth.

Description

A kind of Chinese medicine and preparation method for the treatment of the evil type puerperal general pain of sense
Technical field
The present invention relates to pharmaceutical technology, particularly a kind of Chinese medicine and preparation method for the treatment of the evil type puerperal general pain of sense.
 
Background technology
Puerperal general pain, occurs between puerperal that limbs joint is miserable, pain, numbness, is weighing sense person, is called " puerperal general pain ". and primary disease betides puerperal, belongs to puerperal disease category.Puerpera is because childbirth is lost blood, and consumption is hindered energy, and vessels of the whole body being deficient, easily suffers from general pain, and Etiological has blood deficiency, suffers from a deficiency of the kidney, blood stasis and being invaded by exogenous pathogen etc.
Several pain are below that women often runs into puerperal:
1. wound pain: when childbirth, be difficult to give birth to because perineal position tension makes fetus, doctor has cut a cutter at vaginal orifice.Given birth to baby after several months, knife-edge part wound is still swelled, and presses slightly just pain, and it is very awkward that convalescent new mother can feel at heart.
In general, the scar tissue main component of wound is collagen fiber.Recover a period of time collagen fiber and can be decomposed, absorb, make scar tissue deliquescing, diminish, pain alleviates or disappears.Have minority puerpera to belong to cicatrix body constitution, wound is too much synthetic at healing stage collagen fiber, causes cicatrix hypertrophy, exceeds surrounding skin, has pain and irregular lump, keloid that Here it is while pressing.
2. wrist pain: the new mother who has starts to baby's changing babies' napkin in " in puerperal period ", washes clothes, and also can do some other housework.Soon after, can think that suddenly finger and wrist often ache, especially writing, take chopsticks, the son of cheering, more severe during by feeding bottle, sometimes even can ache and wake up in one's sleep.
When childbirth, open in parent skin pore and joint, and puerperal, QI and blood deficiency, suffered from cold once catch the wind, and wind and cold can be trapped in articular muscle, causes " puerperal fever ".If give baby's changing babies' napkin, breast-feed and do other housework, Overexertion can cause the damage in muscle joint, causes tendon and the nerve injury of finger and wrist, causes " wrist extensor tendinitis " and " complication of wrist ", occurs finger and wrist pain.
3. thigh root pain: given birth to after child, felt some pain of thigh root always.If what take when childbirth is to cut open palace to produce,, can there is thigh root pain and feeling of numbness in injured nerve root while carrying out hard film external anesthetic puncture after operation; Pelvic infection occurs puerperal, and thigh root also there will be pain, but occurs while just pressing, local and painless.In addition the lower limb vein thrombus forming because of childbirth, also can cause thigh pain.
4. sexual love pain: done perineum side cutting when childbirth, after recovery, all can feel vaginal orifice pain after each sexual love, so that start to fear sexual life.If Episiomy Wounds scope be not very greatly, very dark, occur infect time, conventionally can finely heal.The gutstring of sewing up vaginal wall generally came off about 10 days puerperal, and the cicatrix soft surface of formation, does not have obvious sense of discomfort, can not impact sexual life yet.If but Episiomy Wounds infects, or parent itself belongs to cicatrix body constitution, and the time lengthening that will cicatrize a wound or heal badly can produce discomfort or pain after sexual life.
5. extremity pain: often think after bearing child that arm, lower limb and heel ache.Make us becoming lackadaisical, seldom movable, health also recovers very slowly.These pain symptoms are general and pregnant, childbirth is relevant with suckling.
Pregnancy can make human endocrine system change, and causes joint ligament relaxation, and flexibility decrease adds that fetus needs the increase of calcium amount can make parent Decrease of Bone Mineral Density; Childbirth causes QI and blood deficiency, easily causes muscle and arthritis after suffering from cold; Be baby's suckling puerperal, needs calcium amount to continue to increase and more can make the bone density of waist and extremity continue to decline; That have a rest puerperal is improper, stand too early, sit up straight, or holds a baby in one's arms for a long time, or breast-feeds and cause muscle fatigue etc. with a certain anchor, all easily occurs limbs pain in puerperal.
6. dysurea: in a couple of days, feel suddenly always to have urine meaning after bearing child, can feel again pain when urinating.Do urine chemical examination in hospital, but find to have suffered from acute cystitis.
This is straight because female urethra is short, near anus, easily contaminated.Add that point puerperium bladder and ureter muscle are temporarily lax, easily store residual urine.The interior retention moisture of body late trimester of pregnancy, point puerperium mainly discharges from kidney, increases bladder burden, has reduced premunition.These factors easily cause antibacterial to invade bladder and cause inflammation, and occur the symptoms such as dysurea, frequent micturition, urgent micturition.
Motherland's medical science was thought in puerperal, occurred limbs, joint aches, numbness, heavy author, was called " puerperal general pain ", also claimed " pain all over ", " arthralgia in puerperal ".The generation of primary disease is mainly due to deficiency of qi and blood in puerperal, and passages through which vital energy circulates loses supports or plain body deficiency of the kidney, and vessels of the uterus loses supports, and puerperal battalion defends imbalance, interspaces of skin and muscles being loose, and the damp that is affected by the cold, makes due to QI-blood circulation is obstructed.
Puerperal general pain is by Four types:
1. blood deficiency: severe loss of blood when product, or puerperal deficiency of both QI and blood, muscle arteries and veins joint is lost in moistening foster, so that numb limbs and tense tendons, limbs joint is ached.
2. suffer from a deficiency of the kidney: plain body deficiency of the kidney, all empty because of maternal infuries essence and blood, vessels of the uterus loses supports, so that ache of the spinal column, and lower limb knee joint is weak.
3. blood stasis: lochia is not smooth, the blood stasis meridians of being detained, QI-blood circulation is obstructed and dedicate one's life to pain.
4. sense is evil: puerperal deficient qi and blood, disharmony of nutrient QI with defensive QI, interspaces of skin and muscles being loose, if careless because of daily life, wet three heresies of wind and cold are taken advantage of a weak point, and keep meridians, joint, and QI-blood circulation is obstructed, the stasis of blood is stagnant and have a pain.
Blood deficiency the whole body in puerperal arthralgia, limbs are miserable, numb, shallow complexion, skin is not damp, dizzy cardiopalmus, the lazy speech of breathing hard.Light red tongue, thready pulse without strength.
The ache of the spinal column in puerperal of suffering from a deficiency of the kidney, lower limb knee joint is weak, or heel pain.Light red tongue thin fur, deep-thready pulse.
Blood stasis joint aches all in puerperal or pain are more acute, joint joint stuffiness, and lochia is descending not smooth, hypogastralgia tenderness.Purplish tongue, stringy pulse.
Feel evil arthralgia all over, activities adverse, or migratory pain, or severe pain is as thorn, or limb swelling, is weighing erectile problem.White and thin fur, thready and stringy pulse.
Western medical treatment puerperal general pain, therapeutic scheme limitation, conventional analgesic as: aspirin, ibuprofen, indometacin, acetaminophen, Phenylbutazone, rofecoxib etc., treatment is longer the course for the treatment of, does not reach desirable clinical therapeutic efficacy.This type of medicine of prolonged application can cause more untoward reaction and toxic and side effects.Chinese traditional treatment puerperal general pain treatment prognosis is better, on the basis of seeing, is particular about determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs at animal economy, selected fully natural green medical material, the drug effect focus of going directly, treatment is shorter the course for the treatment of, and curative effect is better, toxic and side effects is less, have no adverse reaction, in treatment primary disease, can also play certain health-care effect to body, cost price is cheap, processing technology is simple, can carry out clinical expansion and meet the Treatment need of clinical puerperal general pain.
 
Summary of the invention
The technical problem to be solved in the present invention is to provide one to have nourishing blood to expel wind, and dispelling cold and removing dampness effect cures mainly the Chinese medicine of feeling evil type puerperal general pain.It is better that the present invention has the evil type puerperal general pain treatment for the treatment of sense prognosis, on the basis of seeing, is particular about determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs at animal economy, selected fully natural green medical material, the drug effect focus of going directly, treatment is shorter the course for the treatment of, and curative effect is better, toxic and side effects is less, have no adverse reaction, in treatment primary disease, can also play certain health-care effect to body, cost price is cheap, processing technology is simple, can carry out clinical expansion and meet the feature of the Treatment need of clinical puerperal general pain.
In order to realize foregoing invention object, the invention provides a kind of Chinese medicine for the treatment of the evil type puerperal general pain of sense, it is characterized in that, comprise following raw medicinal material: Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis, Fructus Liquidambaris, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Trigonellae, Cortex schefflerae octophyllae, Rhizoma Humatae Tyermanni, Cortex erythrinae, Colla cornus cervi and Semen Castaneae.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Herba Schizonepetae 22-33 part, Rhizoma Et Radix Notopterygii 14-29 part, Radix Saposhnikoviae 17-33 part, Radix Angelicae Dahuricae 22-37 part, Rhizoma Ligustici 19-35 part, Bulbus Allii Fistulosi 24-38 part, Ramulus et Folium Tamaricis 20-34 part, Herba Lycopodii 15-32 part, Herba Aristolochiae Mollissimae 11-25 part, Caulis Sinomenii 14-31 part, Radix Morindae Officinalis 12-26 part, Fructus Liquidambaris 20-36 part, Caulis Trachelospermi 15-28 part, Caulis Spatholobi 14-32 part, Flos Carthami 16-29 part, Rhizoma Chuanxiong 19-31 part, Rhizoma Corydalis 4-10 part, Rhizoma Curcumae Longae 8-19 part, Semen Vaccariae 13-28 part, Radix Codonopsis 16-37 part, Radix Astragali 24-35 part, Rhizoma Dioscoreae 13-24 part, Radix Glycyrrhizae 18-31 part, Radix Rhodiolae 19-31 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-10 part, Semen Trigonellae 13-30 part, Cortex schefflerae octophyllae 27-42 part, Rhizoma Humatae Tyermanni 16-27 part, Cortex erythrinae 12-27 part, Colla cornus cervi 12-28 part and Semen Castaneae 30-41 part.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Herba Schizonepetae 23-31 part, Rhizoma Et Radix Notopterygii 16-27 part, Radix Saposhnikoviae 19-30 part, Radix Angelicae Dahuricae 25-33 part, Rhizoma Ligustici 20-34 part, Bulbus Allii Fistulosi 26-36 part, Ramulus et Folium Tamaricis 22-32 part, Herba Lycopodii 17-29 part, Herba Aristolochiae Mollissimae 15-25 part, Caulis Sinomenii 18-27 part, Radix Morindae Officinalis 14-24 part, Fructus Liquidambaris 20-32 part, Caulis Trachelospermi 17-26 part, Caulis Spatholobi 18-30 part, Flos Carthami 16-23 part, Rhizoma Chuanxiong 19-29 part, Rhizoma Corydalis 7-10 part, Rhizoma Curcumae Longae 9-18 part, Semen Vaccariae 15-24 part, Radix Codonopsis 18-34 part, Radix Astragali 26-31 part, Rhizoma Dioscoreae 15-21 part, Radix Glycyrrhizae 19-30 part, Radix Rhodiolae 23-30 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 6-9 part, Semen Trigonellae 14-28 part, Cortex schefflerae octophyllae 27-35 part, Rhizoma Humatae Tyermanni 16-23 part, Cortex erythrinae 12-22 part, Colla cornus cervi 12-20 part and Semen Castaneae 30-36 part.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is: 23 parts of Herba Schizonepetae, 19 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 28 parts of the Radixs Angelicae Dahuricae, 20 parts of Rhizoma Ligusticis, 36 parts of Bulbus Allii Fistulosi, 22 parts of Ramulus et Folium Tamariciss, 25 parts of Herba Lycopodiis, 15 parts of Herba Aristolochiae Mollissimaes, 26 parts of Caulis Sinomeniis, 14 parts of Radix Morindae Officinaliss, 29 parts of Fructus Liquidambaris, 17 parts of Caulis Trachelospermis, 28 parts of Caulis Spatholobis, 16 parts, Flos Carthami, 22 parts of Rhizoma Chuanxiongs, 7 parts of Rhizoma Corydalis, 11 parts, Rhizoma Curcumae Longae, 15 parts of Semen Vaccariae, 24 parts of Radix Codonopsis, 31 parts of the Radixs Astragali, 17 parts of Rhizoma Dioscoreaes, 19 parts, Radix Glycyrrhizae, 25 parts of Radix Rhodiolaes, 6 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 18 parts of Semen Trigonellaes, 27 parts of Cortex schefflerae octophyllaes, 18 parts of Rhizoma Humatae Tyermannis, 12 parts of Cortex erythrinaes, 30 parts, 19 parts of Colla cornus cervis and Semen Castaneae.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is: 31 parts of Herba Schizonepetae, 27 parts of Rhizoma Et Radix Notopterygiis, 24 parts of Radix Saposhnikoviaes, 33 parts of the Radixs Angelicae Dahuricae, 34 parts of Rhizoma Ligusticis, 30 parts of Bulbus Allii Fistulosi, 32 parts of Ramulus et Folium Tamariciss, 29 parts of Herba Lycopodiis, 25 parts of Herba Aristolochiae Mollissimaes, 27 parts of Caulis Sinomeniis, 24 parts of Radix Morindae Officinaliss, 32 parts of Fructus Liquidambaris, 26 parts of Caulis Trachelospermis, 30 parts of Caulis Spatholobis, 23 parts, Flos Carthami, 19 parts of Rhizoma Chuanxiongs, 9 parts of Rhizoma Corydalis, 9 parts, Rhizoma Curcumae Longae, 24 parts of Semen Vaccariae, 18 parts of Radix Codonopsis, 26 parts of the Radixs Astragali, 21 parts of Rhizoma Dioscoreaes, 30 parts, Radix Glycyrrhizae, 30 parts of Radix Rhodiolaes, 9 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 28 parts of Semen Trigonellaes, 35 parts of Cortex schefflerae octophyllaes, 23 parts of Rhizoma Humatae Tyermannis, 22 parts of Cortex erythrinaes, 36 parts, 20 parts of Colla cornus cervis and Semen Castaneae.
In described Chinese medicine, the ratio of weight and number of each raw medicinal material is: 27 parts of Herba Schizonepetae, 16 parts of Rhizoma Et Radix Notopterygiis, 19 parts of Radix Saposhnikoviaes, 25 parts of the Radixs Angelicae Dahuricae, 32 parts of Rhizoma Ligusticis, 26 parts of Bulbus Allii Fistulosi, 27 parts of Ramulus et Folium Tamariciss, 17 parts of Herba Lycopodiis, 21 parts of Herba Aristolochiae Mollissimaes, 18 parts of Caulis Sinomeniis, 18 parts of Radix Morindae Officinaliss, 20 parts of Fructus Liquidambaris, 20 parts of Caulis Trachelospermis, 18 parts of Caulis Spatholobis, 18 parts, Flos Carthami, 29 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Corydalis, 18 parts, Rhizoma Curcumae Longae, 16 parts of Semen Vaccariae, 34 parts of Radix Codonopsis, 29 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 27 parts, Radix Glycyrrhizae, 23 parts of Radix Rhodiolaes, 7 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 14 parts of Semen Trigonellaes, 34 parts of Cortex schefflerae octophyllaes, 16 parts of Rhizoma Humatae Tyermannis, 14 parts of Cortex erythrinaes, 33 parts, 12 parts of Colla cornus cervis and Semen Castaneae.
When the dosage form of described Chinese medicine is decoction, its preparation method comprises the following steps:
Step 1: described raw medicinal material is mixed and puts into purple casserole, add clear water, soaked medical material upper surface 2-5cm to clear water, soak 3-10 hour;
Step 2: purple casserole is placed in to fire upper, after intense fire boils, uses slow fire instead and decoct slowly 30-50 minute, filter, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added to clear water again, soaked medical material upper surface 2-3cm to clear water, soak 3-10 hour;
Step 4: purple casserole is placed in to fire upper, after intense fire boils, using slow fire instead, to decoct slowly the 25-35 minute dosage to medicinal liquid be 100-300ml, filters, and obtains filtrate b, and filtrate a and filtrate b are mixed.
When the dosage form of described Chinese medicine is lotion, its preparation method comprises the following steps:
The first step, described raw medicinal material is mixed in proportion, put into super micron mill and be ground into the mixed powder that the micron particles of 0.1~10 μ m volume average particle size and particle diameter are less than the nano-scale particle composition of 0.1 μ m volume average particle size, described mixed powder powder rate be at least 95%;
Second step, the ethanol that to add with respect to the determining alcohol of 3~5 times of the quality of described mixed powder in the mixed powder obtaining in the first step be 85%~95%, stirring and dissolving obtains alcoholic solution, alcoholic solution is left standstill to 24~36 hours under the condition of 5 DEG C~10 DEG C, adopt the speed slowly percolation of percolation with 1~2ml per minute, collect percolate, concentrate and be dried, and put into super micron mill at this and pulverize 40~60 minutes, the micron particles of acquisition 0.1~10 μ m volume average particle size and particle diameter are less than the mixed powder of the nano-scale particle composition of 0.1 μ m volume average particle size, the powder rate that obtains of described mixed powder is at least 95%,
The 3rd step, adds deionized water with respect to mixed powder quality 2~3 times in the mixed powder obtaining at second step, decocts 2~4 hours, filters, and obtains medicine juice.
When the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:
The first step is mixed Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis and Fructus Liquidambaris in described ratio, add the water extraction volatile oil with respect to 4~6 times, mixture, by the volatile oil beta-cyclodextrin inclusion compound obtaining, the mass ratio of volatile oil and beta-schardinger dextrin-is 1: 3~6, stir 60 minutes~90 minutes, 30 DEG C~50 DEG C of temperature, obtain volatile oil clathrate compound, for subsequent use; The clear paste that while separately aqueous extract being concentrated into 60 DEG C, relative density is 1.15~1.17;
Second step, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae and Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) are mixed in described ratio, the alcohol reflux that to add with respect to 5~8 times, mixture amount determining alcohols be 75%~90% 3~5 times, each 2~3 hours, filter respectively, each time filtrate merges, and reclaims ethanol, the clear paste that while being concentrated into 60 DEG C, relative density is 1.20~1.22, for subsequent use;
The 3rd step, will remain described raw medicinal material and mix in described ratio, add with respect to 8~10 times of water gagings of mixture, boil 6~8 hours, filter the clear paste that while being concentrated into 60 DEG C, relative density is 1.28~1.30;
The 4th step, mixes the clear paste of the first step, second step, the 3rd step, and 60 DEG C~70 DEG C reduced vacuum are dry, and powder gets dry extract;
The 5th step, dried cream powder described in volatile oil clathrate compound described in the first step and the 4th step is fully mixed, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 5~7 weight portion carboxymethyl starch sodium, 5~50 weight portion starch mix homogeneously, adding 150~200 weight portion determining alcohols is 80%~90% alcohol granulation, dry, granulate, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 3~5 weight portion magnesium stearate, then pack in gelatine capsule.
For solving the problems of the technologies described above, the invention provides a kind of dosage form of Chinese medicine preparation for the treatment of the evil type puerperal general pain of sense, pharmaceutical dosage form can be: tablet, film coated tablet, capsule, sugar coated tablet, hard capsule, soft capsule, suck agent, granule, enteric coated tablet, electuary, honey pill agent, oral liquid, powder, solution, sublimed preparation, suppository, plaster, syrup, injection, powder.
Medicine is decocted in use decoction and is taken, and 1 dose of every day, decocting takes at twice, and every 6 days is a course for the treatment of; When this Chinese medicine composition is pill, capsule or when sucking agent, tablet and using, three times on the one, every 6 days is a course for the treatment of; In the time that this Chinese medicine composition is spray, patch use, 2-5 time on the one, every 6 days is a course for the treatment of, and in the time that this Chinese medicine composition is lotion use, 1 time on the one, every 6 days is a course for the treatment of.
The beneficial effect that technical scheme provided by the invention is brought is: the present invention has nourishing blood to expel wind, effect of dispelling cold and removing dampness, there is the evil type puerperal general pain treatment for the treatment of sense prognosis better, on the basis of seeing at animal economy, be particular about determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, selected fully natural green medical material, the drug effect focus of going directly, treatment is shorter the course for the treatment of, curative effect is better, toxic and side effects is less, have no adverse reaction, in treatment primary disease, can also play certain health-care effect to body, cost price is cheap, processing technology is simple, clinical expansion can be carried out meet the feature of the Treatment need of clinical puerperal general pain.
 
Detailed description of the invention
Motherland's medical science thinks, it is mainly due to deficiency of qi and blood in puerperal that puerperal general pain occurs, and passages through which vital energy circulates loses supports or plain body deficiency of the kidney, and vessels of the uterus loses supports, and puerperal, battalion defended imbalance, interspaces of skin and muscles being loose, and the damp that is affected by the cold, makes due to QI-blood circulation is obstructed.Therefore, the present invention treats the evil type puerperal general pain of sense with nourishing blood to expel wind, dispelling cold and removing dampness is primary treatment principle, selects Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis, Fructus Liquidambaris, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Trigonellae, Cortex schefflerae octophyllae, Rhizoma Humatae Tyermanni, Cortex erythrinae, Colla cornus cervi and Semen Castaneae.
Wherein, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Cortex schefflerae octophyllae, Rhizoma Humatae Tyermanni expelling pathogenic wind from the body surface, pain relieving; Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis, Fructus Liquidambaris, Caulis Trachelospermi, Cortex erythrinae wind-damp dispelling, channels sootheing and network vessel quickening pain relieving; Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae promoting blood circulation, dredging meridian and relieving pain; The pain relieving of tonifying Qi of the kidney, enrich blood of Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Trigonellae, Colla cornus cervi, Semen Castaneae.
Wherein, the pharmacology of above-mentioned raw materials medical material is as follows:
Herba Schizonepetae: acrid in the mouth, micro-hardship, property is micro-wet.Return lung, Liver Channel.Main cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, carbuncle, skin ulcer scabies, puerperal blood faints.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.Main all joints being painful all over, flesh table eight winds coming from eight orientations harmful climatic factors, except new and old rheumatism, row's slough cellulitis skin ulcer.The function exterior cold of faling apart, wind-damp dispelling, sharp joint, pain relieving.Main affection of exogenous wind-cold, has a headache lossless, edema due to wind pathogen edema, sore swollen toxin.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.The cold expelling that induces sweat, expelling wind and dampness, pain relieving.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.Return urinary bladder channel, lung meridian, spleen channel, Liver Channel.Function expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.For affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, joint is ached, stomachache is had loose bowels, discharging fresh blood stool, tetanus, rubella pruritus, skin infection from the beginning of.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Return lung, stomach, large intestine channel.Function expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidifying are sensible, detumescence and apocenosis.Cure mainly anemofrigid cold, headache, supraorbital bone pain, toothache, eye itching lacrimation, nasal obstruction, nasal sinusitis, wet chronic diarrhea, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, pruritus scabies, the venom contained.
Rhizoma Ligustici: hardship, pungent, cold.Return liver, gallbladder meridian, three warmers, kidney channel.Function: clear deficiency-heat thoroughly, removing heat from blood, except steaming, removes and steams, preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.This product clearing up internal heat by using drugs of bitter in taste and cold in nature, pungent perfume (or spice) is thoroughly loose, and the kind the moon that makes divides a latent heat thoroughly to reach outer faling apart, and is fever due to yin deficiency key medicine, has in addition expelling summer-heat, cuts cruel merit.
Bulbus Allii Fistulosi: enter lung, stomach warp.Except rheumatism, general pain paralysis, malnutrition due to parasitic infestation is pained, only adult Yang Tuo, and insidious stomachache, children's is coiled enteral and is angled, married woman's gestation hematuria, logical milk, loose acute mastitis, sharp tinnitus, is coated with dog poison.Function is delivered, is activated yang, removing toxic substances, parasite killing.Cure mainly cold, YIN-cold stomachache, constipation and anuresis, dysentery, sore, carbuncle and painful swelling, abdominal pain due to worm stagnation.
Ramulus et Folium Tamaricis: sweet in the mouth, pungent, property are flat.Return lung meridian, stomach warp, heart channel.Cure mainly anemopyretic cold, measles from the beginning of, rash goes out not saturating, rheumatic arthralgia, skin pruritus.Control measles thoroughly difficult, rubella itching over the body, flu, cough with asthma, rheumatic ostalgia.
Herba Lycopodii: bitter, pungent, warm.Return Liver Channel.Expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.
Herba Aristolochiae Mollissimae: bitter in the mouth is flat.Return Liver Channel.Wind-damp dispelling, the meridian dredging, pain relieving.For rheumatic arthralgia, numb limbs and tense tendons, muscles and bones contracture, traumatic injury pain.
Caulis Sinomenii: bitter, pungent.Return liver, spleen channel.Row water diuresis, rushes down part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels blood system damp and hot.Control edema caused by wind, beriberi, Fengshi Guanjie pain, facial hemiparalysis, carbuncle malignant boil.Function wind-damp dispelling, the meridian dredging, diuresis.For rheumatic arthralgia, arthroncus, paralysis pruritus.Caulis Sinomenii dispersing wind and cold arthralgia chiefly caused by damp pathogen, can relaxing muscles and tendons to promote blood circulation, the sharp marrow that bonesets, thus syndrome caused by wind pathogen weakness, and the card attached undue importance to one thing to the neglect of the other by force of strength, take for a long time informal dress, make outstanding contributions greatly.
Radix Morindae Officinalis: acrid in the mouth, sweet, warm in nature.Return liver, kidney channel.There is reinforcing the kidney and supporting YANG, bone and muscle strengthening, effect of expelling wind and removing dampness.Cure mainly impotence due to deficiency of the kidney, seminal emission premature ejaculation, few abdomen cold type of pain, incontinence of urine, cold womb is infertile, anemofrigid-damp arthralgia, soreness of the waist and knees, the cards such as rheumatism limb gas.
Fructus Liquidambaris: hardship, flat.Return liver, kidney channel.Dispelling, collateral-activating, diuretic stimulates the menstrual flow.
Caulis Trachelospermi: hardship, is slightly cold.GUIXIN, liver, kidney channel.There is expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, clearing away heat and cooling blood, effect of removing toxic substances and promoting subsidence of swelling, cures mainly dispelling wind and removing obstruction in the collateral, removing heat from blood detumescence.For rheumatism pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, carbuncle, injury from falling down.
Caulis Spatholobi: bitter in the mouth, sweet, warm in nature.Returning liver, kidney channel, is the hematonic of robustness, is applicable to the neural paralysis disease of anemia, as limbs and soreness of waist and knee joint, apathetic etc.Again for menoxenia, menstruation apolipsis etc., have the effect of invigorating blood circulation analgesia.There is blood vessel dilating, enrich blood and invigorate blood circulation, regulating menstruation, effect of relaxing muscles and tendons and activating QI and blood in the collateral, has obvious inhibitory action to platelet aggregation, promotes animal kidney and the total phosphorus metabolism in uterus, being mainly used in treating blood deficiency has the menoxenia of silt, and limbs pain is meciless, the cards such as soreness of the waist and knees, pain.Join Herba Leonuri, blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving; Join Rhizoma Atractylodis, regulating QI to expel dampness, ward off dirty go turbid; Join the Cortex Eucommiae, invigorating the kidney and strengthening the bones, inducing menstruation to relieve menalgia; Join Radix Angelicae Sinensis, enrich blood and invigorate blood circulation.
Flos Carthami: warm in nature, acrid in the mouth.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, heart channel.Control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, and strengthening bone and muscle, adjusts many arteries and veins, and broken crux stagnated blood, supports fresh blood, puts on flesh, and serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, scrofula wart is superfluous, skin ulcer scabies, and evacuation of pus repercussive blood.The fragrant liter of gas fallen apart.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.Cure mainly menoxenia, dysmenorrhea, amenorrhea, difficult labour, retention of placenta, lochia stomachache, lump, heart pain in chest and hypochondrium, traumatic injury swells and ache, headache vertigo and head dark, anemofrigid-damp arthralgia, numb limbs and tense tendons, ulcer sores.For headache due to common cold, the diseases such as migraine and general headache.
Rhizoma Corydalis: bitter in the mouth, pungent, warm in nature.Return liver, the heart, stomach warp.Have benefaction and wander away, can rise and can fall, have promoting blood circulation to remove blood stasis, effect of promoting the circulation of QI to relieve pain, cures mainly obstruction of qi in the chest and cardialgia, side of body rib, all pains of gastral cavity abdomen, and headache, lumbago, colicky, bones and muscles pain, dysmenorrhea, amenorrhea, puerperal, the stasis of blood was suffered from abdominal pain, the cards such as traumatic injury.
Rhizoma Curcumae Longae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.There is removing blood stasis circulation of qi promoting, effect of inducing menstruation to relieve menalgia.For amenorrhea due to stagnation of blood, menalgia, the breast side of body twinges, rheumatic arthralgia, shoulder arm pain, the cards such as injury from falling down.
Semen Vaccariae: hardship, flat.Return liver, stomach warp.Can promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, the lactogenesis of invigorating blood circulation, expedite the emergence of stimulating milk secretion, thymus dredging in puerperal.For blood stasis amenorrhea, dysmenorrhea, difficult labour; Lack of lactation after delivery, acute mastitis swells and ache; Pyretic stranguria, stranguria with blood, stranguria caused by urinary stone.
Radix Codonopsis: property is flat, sweet in the mouth, micro-acid.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.Function consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.The Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect.The real table of function, person does not use pathogenic factor in the exterior; Can help gas, can interiorly fill in, tonifying for the deficiency, chest and diaphragm is gas-tight asks; Can YANG invigorating.
Rhizoma Dioscoreae: sweet in the mouth, property is flat.Return lung, spleen, kidney channel.There is strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help that the five internal organs, bone and muscle strengthening, long will are calmed the nerves, effect of life lengthening, cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity are weak, the red card such as swollen, fat of the frequent micturition of quenching one's thirst, the premature ejaculation of passing out semen, leukorrhagia nebulousurine, skin.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.
Radix Glycyrrhizae: nature and flavor are sweet, flat.Return spleen, stomach, lung meridian.Can QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription.Main asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, the anxious pain of extremity contraction, hysteria, cough and asthma, laryngopharynx swelling and pain, carbuncle skin ulcer swells and ache, infantile carbuncle, and medicine, alimentary toxicosis.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Rhodiolae: sweet, hardship, flat.Return lung, heart channel.Can improve sleep, blood-enriching and blood-promoting circulation, anti-cerebral anoxia, resisting fatigue, promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough, change become silted up detumescence, antipyreticly bring down a fever, nourish the effects such as vigour; Be used for the treatment of traumatic injury and burn and scald outward.
Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani): bitter, pungent, temperature, very toxic.Return Liver Channel.The pungent loose temperature of these product is logical, and property is apt to away suddenly, can wind-damp dispelling, and the arteries and veins of invigorating blood circulation, especially kind pain relieving, for treating the good medicine of multiple pain, can treating the poisonous disease with poisonous drugs, promoting blood circulation and stopping pain, the available outer wiping of steeping in wine, controls sore swollen toxin, and poisonous insect and venom, honeybee sting etc.
Semen Trigonellae: hardship, temperature.Return kidney channel.Control cold air hernia abdominal mass, the disturbance of lower legs due to pathogenic cold and dampness; The right kidney of benefit, warm public region.There are the kidney invigorating wind dispelling, supporing yang analgesic effect, have that refreshing people's body and mind, quiet brain are calmed the nerves, the effect of lax nerve, relieving fatigue, removing obstruction in the collateral to relieve pain, replenishing kidney-YIN tonifying YANG, be usually used in treating the illness such as sexual impotence spermatorrhea, sore waist and aching in the waist and the back, young married woman's dysmenorrhea, the hernia swelling and hanging down of either of the testes, the disturbance of lower legs due to pathogenic cold and dampness.
Cortex schefflerae octophyllae: acrid in the mouth; Bitter; Cool in nature.Relieving the exterior syndrome by diaphoresis; Expelling wind and removing dampness; Relaxing muscles and tendons and activating QI and blood in the collateral.Main cold, fever, laryngopharynx swelling and pain; Scald; Innominate toxic swelling; Rheumatic arthralgia; Traumatic injury damages and beats; Fracture.
Rhizoma Humatae Tyermanni: sweet in the mouth; Property is put down.Return lung; Liver; Spleen channel.The lung heat clearing of inducing sweat; Eliminating damp, detoxifying; Tonify deficiency spleen invigorating.Main anemopyretic cold; Cough due to consumptive disease; Jaundice; Stranguria; Sore swells and ache; Venom.
Cortex erythrinae: hardship; Pungent; Flat.Return liver; Spleen; Stomach warp.Expelling wind and removing dampness; Channels sootheing and network vessel quickening; Killing parasites for relieving itching.Main air pain of dampness syndrome; Podomere contracture; Traumatic injury; Scabies; Eczema.
Colla cornus cervi: sweet in the mouth; Salty; Warm in nature.Return liver; Kidney channel.Enrich and benefit essence and blood; Antiabortive hemostasis.Main suffering from a deficiency of the kidney; Asthenia of essence and blood; Asthenia is won thin; Dizziness and tinnitus; Soreness of the waist and knees, sexual impotence spermatorrhea; Infertility; Frequent fetal movement; Bleeding not during menses; Spit blood; Epistaxis; Spitting of blood; Urinate standby; Carbuncle of yin nature skin infection.
Semen Castaneae: sweet; Micro-salty; Property is put down.Return spleen; Kidney channel.Replenishing QI to invigorate the spleen; The strong muscle of the kidney invigorating; Promoting blood circulation and detumescence, hemostasis.Main diarrhea due to hypofunction of the spleen; Regurgitation vomiting; Foot knees soreness; Injured bone swells and ache; Scrofula; Spit blood; Epistaxis; Have blood in stool.
Wherein, in Chinese medicine, the ratio of weight and number of each raw medicinal material is: Herba Schizonepetae 22-33 part, Rhizoma Et Radix Notopterygii 14-29 part, Radix Saposhnikoviae 17-33 part, Radix Angelicae Dahuricae 22-37 part, Rhizoma Ligustici 19-35 part, Bulbus Allii Fistulosi 24-38 part, Ramulus et Folium Tamaricis 20-34 part, Herba Lycopodii 15-32 part, Herba Aristolochiae Mollissimae 11-25 part, Caulis Sinomenii 14-31 part, Radix Morindae Officinalis 12-26 part, Fructus Liquidambaris 20-36 part, Caulis Trachelospermi 15-28 part, Caulis Spatholobi 14-32 part, Flos Carthami 16-29 part, Rhizoma Chuanxiong 19-31 part, Rhizoma Corydalis 4-10 part, Rhizoma Curcumae Longae 8-19 part, Semen Vaccariae 13-28 part, Radix Codonopsis 16-37 part, Radix Astragali 24-35 part, Rhizoma Dioscoreae 13-24 part, Radix Glycyrrhizae 18-31 part, Radix Rhodiolae 19-31 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-10 part, Semen Trigonellae 13-30 part, Cortex schefflerae octophyllae 27-42 part, Rhizoma Humatae Tyermanni 16-27 part, Cortex erythrinae 12-27 part, Colla cornus cervi 12-28 part and Semen Castaneae 30-41 part.
Wherein, in Chinese medicine, the ratio of weight and number of each raw medicinal material is: Herba Schizonepetae 23-31 part, Rhizoma Et Radix Notopterygii 16-27 part, Radix Saposhnikoviae 19-30 part, Radix Angelicae Dahuricae 25-33 part, Rhizoma Ligustici 20-34 part, Bulbus Allii Fistulosi 26-36 part, Ramulus et Folium Tamaricis 22-32 part, Herba Lycopodii 17-29 part, Herba Aristolochiae Mollissimae 15-25 part, Caulis Sinomenii 18-27 part, Radix Morindae Officinalis 14-24 part, Fructus Liquidambaris 20-32 part, Caulis Trachelospermi 17-26 part, Caulis Spatholobi 18-30 part, Flos Carthami 16-23 part, Rhizoma Chuanxiong 19-29 part, Rhizoma Corydalis 7-10 part, Rhizoma Curcumae Longae 9-18 part, Semen Vaccariae 15-24 part, Radix Codonopsis 18-34 part, Radix Astragali 26-31 part, Rhizoma Dioscoreae 15-21 part, Radix Glycyrrhizae 19-30 part, Radix Rhodiolae 23-30 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 6-9 part, Semen Trigonellae 14-28 part, Cortex schefflerae octophyllae 27-35 part, Rhizoma Humatae Tyermanni 16-23 part, Cortex erythrinae 12-22 part, Colla cornus cervi 12-20 part and Semen Castaneae 30-36 part.
Wherein, in Chinese medicine, the ratio of weight and number of each raw medicinal material is: 23 parts of Herba Schizonepetae, 19 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 28 parts of the Radixs Angelicae Dahuricae, 20 parts of Rhizoma Ligusticis, 36 parts of Bulbus Allii Fistulosi, 22 parts of Ramulus et Folium Tamariciss, 25 parts of Herba Lycopodiis, 15 parts of Herba Aristolochiae Mollissimaes, 26 parts of Caulis Sinomeniis, 14 parts of Radix Morindae Officinaliss, 29 parts of Fructus Liquidambaris, 17 parts of Caulis Trachelospermis, 28 parts of Caulis Spatholobis, 16 parts, Flos Carthami, 22 parts of Rhizoma Chuanxiongs, 7 parts of Rhizoma Corydalis, 11 parts, Rhizoma Curcumae Longae, 15 parts of Semen Vaccariae, 24 parts of Radix Codonopsis, 31 parts of the Radixs Astragali, 17 parts of Rhizoma Dioscoreaes, 19 parts, Radix Glycyrrhizae, 25 parts of Radix Rhodiolaes, 6 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 18 parts of Semen Trigonellaes, 27 parts of Cortex schefflerae octophyllaes, 18 parts of Rhizoma Humatae Tyermannis, 12 parts of Cortex erythrinaes, 30 parts, 19 parts of Colla cornus cervis and Semen Castaneae.
Wherein, in Chinese medicine, the ratio of weight and number of each raw medicinal material is: 31 parts of Herba Schizonepetae, 27 parts of Rhizoma Et Radix Notopterygiis, 24 parts of Radix Saposhnikoviaes, 33 parts of the Radixs Angelicae Dahuricae, 34 parts of Rhizoma Ligusticis, 30 parts of Bulbus Allii Fistulosi, 32 parts of Ramulus et Folium Tamariciss, 29 parts of Herba Lycopodiis, 25 parts of Herba Aristolochiae Mollissimaes, 27 parts of Caulis Sinomeniis, 24 parts of Radix Morindae Officinaliss, 32 parts of Fructus Liquidambaris, 26 parts of Caulis Trachelospermis, 30 parts of Caulis Spatholobis, 23 parts, Flos Carthami, 19 parts of Rhizoma Chuanxiongs, 9 parts of Rhizoma Corydalis, 9 parts, Rhizoma Curcumae Longae, 24 parts of Semen Vaccariae, 18 parts of Radix Codonopsis, 26 parts of the Radixs Astragali, 21 parts of Rhizoma Dioscoreaes, 30 parts, Radix Glycyrrhizae, 30 parts of Radix Rhodiolaes, 9 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 28 parts of Semen Trigonellaes, 35 parts of Cortex schefflerae octophyllaes, 23 parts of Rhizoma Humatae Tyermannis, 22 parts of Cortex erythrinaes, 36 parts, 20 parts of Colla cornus cervis and Semen Castaneae.
Wherein, in Chinese medicine, the ratio of weight and number of each raw medicinal material is: 27 parts of Herba Schizonepetae, 16 parts of Rhizoma Et Radix Notopterygiis, 19 parts of Radix Saposhnikoviaes, 25 parts of the Radixs Angelicae Dahuricae, 32 parts of Rhizoma Ligusticis, 26 parts of Bulbus Allii Fistulosi, 27 parts of Ramulus et Folium Tamariciss, 17 parts of Herba Lycopodiis, 21 parts of Herba Aristolochiae Mollissimaes, 18 parts of Caulis Sinomeniis, 18 parts of Radix Morindae Officinaliss, 20 parts of Fructus Liquidambaris, 20 parts of Caulis Trachelospermis, 18 parts of Caulis Spatholobis, 18 parts, Flos Carthami, 29 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Corydalis, 18 parts, Rhizoma Curcumae Longae, 16 parts of Semen Vaccariae, 34 parts of Radix Codonopsis, 29 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 27 parts, Radix Glycyrrhizae, 23 parts of Radix Rhodiolaes, 7 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 14 parts of Semen Trigonellaes, 34 parts of Cortex schefflerae octophyllaes, 16 parts of Rhizoma Humatae Tyermannis, 14 parts of Cortex erythrinaes, 33 parts, 12 parts of Colla cornus cervis and Semen Castaneae.
Wherein, when the dosage form of Chinese medicine is decoction, its preparation method comprises the following steps:
Step 1: described raw medicinal material is mixed and puts into purple casserole, add clear water, soaked medical material upper surface 2-5cm to clear water, soak 3-10 hour;
Step 2: purple casserole is placed in to fire upper, after intense fire boils, uses slow fire instead and decoct slowly 30-50 minute, filter, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added to clear water again, soaked medical material upper surface 2-3cm to clear water, soak 3-10 hour;
Step 4: purple casserole is placed in to fire upper, after intense fire boils, using slow fire instead, to decoct slowly the 25-35 minute dosage to medicinal liquid be 100-300ml, filters, and obtains filtrate b, and filtrate a and filtrate b are mixed.
Wherein, when the dosage form of Chinese medicine is lotion, its preparation method comprises the following steps:
The first step, described raw medicinal material is mixed in proportion, put into super micron mill and be ground into the mixed powder that the micron particles of 0.1~10 μ m volume average particle size and particle diameter are less than the nano-scale particle composition of 0.1 μ m volume average particle size, described mixed powder powder rate be at least 95%;
Second step, the ethanol that to add with respect to the determining alcohol of 3~5 times of the quality of described mixed powder in the mixed powder obtaining in the first step be 85%~95%, stirring and dissolving obtains alcoholic solution, alcoholic solution is left standstill to 24~36 hours under the condition of 5 DEG C~10 DEG C, adopt the speed slowly percolation of percolation with 1~2ml per minute, collect percolate, concentrate and be dried, and put into super micron mill at this and pulverize 40~60 minutes, the micron particles of acquisition 0.1~10 μ m volume average particle size and particle diameter are less than the mixed powder of the nano-scale particle composition of 0.1 μ m volume average particle size, the powder rate that obtains of described mixed powder is at least 95%,
The 3rd step, adds deionized water with respect to mixed powder quality 2~3 times in the mixed powder obtaining at second step, decocts 2~4 hours, filters, and obtains medicine juice.
Wherein, when the dosage form of Chinese medicine is capsule, its preparation method comprises the following steps:
The first step by Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae,, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis and Fructus Liquidambaris mix in described ratio, add the water extraction volatile oil with respect to 4~6 times, mixture, by the volatile oil beta-cyclodextrin inclusion compound obtaining, the mass ratio of volatile oil and beta-schardinger dextrin-is 1: 3~6, stir 60 minutes~90 minutes, 30 DEG C~50 DEG C of temperature, obtain volatile oil clathrate compound, for subsequent use; The clear paste that while separately aqueous extract being concentrated into 60 DEG C, relative density is 1.15~1.17;
Second step, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae and Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) are mixed in described ratio, the alcohol reflux that to add with respect to 5~8 times, mixture amount determining alcohols be 75%~90% 3~5 times, each 2~3 hours, filter respectively, each time filtrate merges, and reclaims ethanol, the clear paste that while being concentrated into 60 DEG C, relative density is 1.20~1.22, for subsequent use;
The 3rd step, will remain described raw medicinal material and mix in described ratio, add with respect to 8~10 times of water gagings of mixture, boil 6~8 hours, filter the clear paste that while being concentrated into 60 DEG C, relative density is 1.28~1.30;
The 4th step, mixes the clear paste of the first step, second step, the 3rd step, and 60 DEG C~70 DEG C reduced vacuum are dry, and powder gets dry extract;
The 5th step, dried cream powder described in volatile oil clathrate compound described in the first step and the 4th step is fully mixed, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 5~7 weight portion carboxymethyl starch sodium, 5~50 weight portion starch mix homogeneously, adding 150~200 weight portion determining alcohols is 80%~90% alcohol granulation, dry, granulate, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 3~5 weight portion magnesium stearate, then pack in gelatine capsule.
 
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Wherein, in Chinese medicine, the ratio of weight and number of each raw medicinal material is:
Embodiment 1 decoction of the present invention
Get Herba Schizonepetae 23g, Rhizoma Et Radix Notopterygii 19g, Radix Saposhnikoviae 30g, Radix Angelicae Dahuricae 28g, Rhizoma Ligustici 20g, Bulbus Allii Fistulosi 36g, Ramulus et Folium Tamaricis 22g, Herba Lycopodii 25g, Herba Aristolochiae Mollissimae 15g, Caulis Sinomenii 26g, Radix Morindae Officinalis 14g, Fructus Liquidambaris 29g, Caulis Trachelospermi 17g, Caulis Spatholobi 28g, Flos Carthami 16g, Rhizoma Chuanxiong 22g, Rhizoma Corydalis 7g, Rhizoma Curcumae Longae 11g, Semen Vaccariae 15g, Radix Codonopsis 24g, Radix Astragali 31g, Rhizoma Dioscoreae 17g, Radix Glycyrrhizae 19g, Radix Rhodiolae 25g, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 6g, Semen Trigonellae 18g, Cortex schefflerae octophyllae 27g, Rhizoma Humatae Tyermanni 18g, Cortex erythrinae 12g, Colla cornus cervi 19g and Semen Castaneae 30g.
Its preparation method comprises the following steps:
Step 1: described raw medicinal material is mixed and puts into purple casserole, add clear water, soaked medical material upper surface 3cm to clear water, soak 3 hours;
Step 2: purple casserole is placed in to fire upper, after intense fire boils, uses slow fire instead and decoct slowly 50 minutes, filter, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added to clear water again, soaked medical material upper surface 3cm to clear water, soak 4 hours;
Step 4: purple casserole is placed in to fire upper, after intense fire boils, using slow fire instead, to decoct slowly the 30 minutes dosage to medicinal liquid be 300ml, filters, and obtains filtrate b, and filtrate a and filtrate b are mixed.
 
Embodiment 2 lotion of the present invention
Get Herba Schizonepetae 31g, Rhizoma Et Radix Notopterygii 27g, Radix Saposhnikoviae 24g, Radix Angelicae Dahuricae 33g, Rhizoma Ligustici 34g, Bulbus Allii Fistulosi 30g, Ramulus et Folium Tamaricis 32g, Herba Lycopodii 29g, Herba Aristolochiae Mollissimae 25g, Caulis Sinomenii 27g, Radix Morindae Officinalis 24g, Fructus Liquidambaris 32g, Caulis Trachelospermi 26g, Caulis Spatholobi 30g, Flos Carthami 23g, Rhizoma Chuanxiong 19g, Rhizoma Corydalis 9g, Rhizoma Curcumae Longae 9g, Semen Vaccariae 24g, Radix Codonopsis 18g, Radix Astragali 26g, Rhizoma Dioscoreae 21g, Radix Glycyrrhizae 30g, Radix Rhodiolae 30g, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 9g, Semen Trigonellae 28g, Cortex schefflerae octophyllae 35g, Rhizoma Humatae Tyermanni 23g, Cortex erythrinae 22g, Colla cornus cervi 20g and Semen Castaneae 36g.
Its preparation method comprises the following steps:
The first step, described raw medicinal material is mixed in proportion, put into super micron mill and be ground into the mixed powder that the micron particles of 5 μ m volume average particle size and particle diameter are less than the nano-scale particle composition of 0.1 μ m volume average particle size, described mixed powder powder rate be at least 95%;
Second step, the ethanol that to add with respect to the determining alcohol of 4 times of the quality of described mixed powder in the mixed powder obtaining in the first step be 95%, stirring and dissolving obtains alcoholic solution, alcoholic solution is left standstill to 36 hours under the condition of 10 DEG C, adopt the speed slowly percolation of percolation with 2ml per minute, collect percolate, concentrate and be dried, and put into super micron mill at this and pulverize 60 minutes, obtain the mixed powder that the micron particles of 5 μ m volume average particle size and particle diameter are less than the nano-scale particle composition of 0.1 μ m volume average particle size, the powder rate that obtains of described mixed powder is at least 95%,
The 3rd step, adds deionized water with respect to mixed powder quality 3 times in the mixed powder obtaining at second step, decocts 3 hours, filters, and obtains medicine juice.
       
Embodiment 3 capsule of the present invention
Get Herba Schizonepetae 27g, Rhizoma Et Radix Notopterygii 16g, Radix Saposhnikoviae 19g, Radix Angelicae Dahuricae 25g, Rhizoma Ligustici 32g, Bulbus Allii Fistulosi 26g, Ramulus et Folium Tamaricis 27g, Herba Lycopodii 17g, Herba Aristolochiae Mollissimae 21g, Caulis Sinomenii 18g, Radix Morindae Officinalis 18g, Fructus Liquidambaris 20g, Caulis Trachelospermi 20g, Caulis Spatholobi 18g, Flos Carthami 18g, Rhizoma Chuanxiong 29g, Rhizoma Corydalis 10g, Rhizoma Curcumae Longae 18g, Semen Vaccariae 16g, Radix Codonopsis 34g, Radix Astragali 29g, Rhizoma Dioscoreae 15g, Radix Glycyrrhizae 27g, Radix Rhodiolae 23g, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 7g, Semen Trigonellae 14g, Cortex schefflerae octophyllae 34g, Rhizoma Humatae Tyermanni 16g, Cortex erythrinae 14g, Colla cornus cervi 12g and Semen Castaneae 33g.
Its preparation method comprises the following steps:
The first step is mixed Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis and Fructus Liquidambaris in described ratio, add the water extraction volatile oil with respect to 5 times, mixture, by the volatile oil beta-cyclodextrin inclusion compound obtaining, the mass ratio of volatile oil and beta-schardinger dextrin-is 1: 5, stir 60 minutes, temperature 50 C, obtains volatile oil clathrate compound, for subsequent use; The clear paste that while separately aqueous extract being concentrated into 60 DEG C, relative density is 1.17;
Second step, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae and Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) are mixed in described ratio, the alcohol reflux that to add with respect to 8 times, mixture amount determining alcohols be 90% 4 times, each 3 hours, filter respectively, each time filtrate merges, and reclaims ethanol, the clear paste that while being concentrated into 60 DEG C, relative density is 1.22, for subsequent use;
The 3rd step, will remain described raw medicinal material and mix in described ratio, add with respect to 9 times of water gagings of mixture, boil 7 hours, filter the clear paste that while being concentrated into 60 DEG C, relative density is 1.30;
The 4th step, mixes the clear paste of the first step, second step, the 3rd step, and 70 DEG C of reduced vacuum are dry, and powder gets dry extract;
The 5th step, dried cream powder described in volatile oil clathrate compound described in the first step and the 4th step is fully mixed, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 6 weight portion carboxymethyl starch sodium, 40 weight portion starch mix homogeneously, adding 180 weight portion determining alcohols is 90% alcohol granulation, dry, granulate, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 4 weight portion magnesium stearate, then pack in gelatine capsule.
 
Acute skin irritation test:
These product are according to 6.3 joints in Ministry of Public Health " cosmetics health specification " (2002) Part II " skin irritation/corrosion test ", male 4 of Japan large ear rabbit, body weight 2kg~3kg, lotion prepared by embodiments of the invention 2 is directly coated on the skin of animal left side (opposite side in contrast), adopt blocking test, 4 hours application time, after off-test, use the residual tested material of warm water washing, 1h after removing tested material, 24h, 48h and 72h observe respectively the dermoreaction of the tested district of animal and check plot, top average is " 0 ", judge that these product are to animal skin nonirritant.
 
Hypersensitive test:
Get 18 of healthy albino guinea-pigs, body weight 250-300g, male and female dual-purpose, rejects both sides dorsal body setae before test, and every side 3 × 3cm, is divided into test group, blank group (substrate) and positive controls at random.Positive controls DNFB, sensitization 1% concentration, excites and uses 0.1% concentration; The lotion of the embodiment of the present invention 2 for test group.The lotion of the embodiment of the present invention 2 is applied to unhairing district, back, the next day 1 time, totally 3 times.Contact latter 14 days in last, be coated with the lotion of the embodiment of the present invention 2 at back the same area, at once observe after removing medicine after 6h, and in 24,48,72h observes and has or not anaphylaxis.Blank group is used same method to excite with positive controls and is contacted and observe.Result of the test: localized erythema and slight edema appear in positive controls animal skin after 1 hour in sensitization, within 24 hours, symptoms of allergic increases the weight of, and there is scleroma to form, sensitization rate is 100%, all there is not any symptoms of allergic in test group and blank treated animal skin, sensitization rate is 0%.
 
Acute toxicity test:
40 of application NIH mices, SPF level, male and female half and half, body weight 18~22g, carries out acute toxicity test.Mice is divided into two groups at random, and 20 every group, i.e. matched group and administration group, fasting 12 hours before experiment; Decoction prepared by embodiments of the invention 1, (concentration is 6.58g crude drug/ml, maximum concentration) gavage, gavage volume is that 5ml/kg(is that single-dose dosage is 32.9 crude drugs/kg), matched group gives equivalent normal saline, administration in a day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: with matched group comparison, after administration, mice has no notable difference, experiment Continuous Observation 14 days, and mice overall health of patients, diet, drinking-water, body weight gain are all normal.Mice oral administration gavage decoction LD50>32.9 of the present invention crude drug/kg, every day, maximum dosage-feeding was 65.8 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention is 4.4g crude drug/day/people, becomes body weight for humans in 60KG, and average dosage is 0.073g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is taking 20g) oral administration gavage Chinese medicine of the present invention is 901 times of quantity.Therefore the decoction acute toxicity of the embodiment of the present invention 1 is low, clinical drug safety.
Long term toxicity test:
The capsule of the embodiment of the present invention 3 to mice by 10.78,20.35 and 16 weeks (1.0ml/100g body weight of 33.48g crude drug/kg continuous use, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as the hair of Chinese medicine of the present invention to mice, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat all has no significant effect, internal organs naked eyes do not find that difference changes and histological examination result shows, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.The capsule that the embodiment of the present invention 3 is described to mice long-term prescription after toxicity little, after drug withdrawal, there is no difference reaction, application safety yet.
 
Clinical data:
This group case is clinic case, totally 110 examples, wherein age reckling 23 years old, the maximum 43 years old, 29 years old mean age.The first tire example in puerperal 82, second fetus example in puerperal 28, natural labor 90 examples, cesarean 20 examples; The course of disease is person's 26 examples within January in puerperal, 1~March person's 28 examples, 3~June person's 40 examples, June above person's 16 examples; Be divided at random:
Decoction treatment group: 26 people.
Lotion for treatment group: 28 people.
Capsule treatment group: 28 people.
Western medicine group: 28 people.
 
Diagnostic criteria:
Western medicine diagnose standard
(1) there is the time of producing more or lose blood puerperal morely, experience the evil medical history of wind, cold, wet;
(2) puerpera's limbs joint ache, numbness, but local without red and swollen scorching hot;
(3) should differentiate mutually with the joint aches that myopathy, rheumatism arthromyodynia etc. cause.
Tcm diagnosis standard
Arthralgia all over, activities adverse, or migratory pain, or severe pain is as thorn, or limb swelling, is weighing erectile problem.White and thin fur, thready and stringy pulse.
 
Therapeutic Method:
Decoction treatment group: the decoction that uses the embodiment of the present invention 1 to prepare, 6 days is 1 course for the treatment of at 1 dose of every day.
Lotion for treatment group: the lotion that uses the embodiment of the present invention 2 to prepare, 6 days is 1 course for the treatment of at every day 1 time.
Capsule treatment group: the capsule that uses the embodiment of the present invention 3 to prepare, every day 3 times, each 66 days is 1 course for the treatment of.
Matched group: the main ingredients of " Chanhouning " capsule: the Radix Astragali, Radix Angelicae Sinensis (processed with wine), Radix Stephaniae Tetrandrae, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Ramulus Cinnamomi, Herba Asari, Semen Persicae, Sanguis Draxonis, Radix Glycyrrhizae etc., 0.5 gram every, each 5, every day 3 times, warm water delivery service, 6 days 1 courses for the treatment of.
 
Efficacy assessment standard:
Recovery from illness: the symptom functional rehabilitation that all disappears is normal;
Effective: cardinal symptom disappears substantially, limbs pain obviously alleviates, and function of joint is recovered normal person substantially;
Effective: symptom alleviates, the incomplete recuperator of function;
Invalid: pain, without obviously alleviating, has no improvement person after treatment.
Therapeutic outcome:
Referring to table 1 and table 2, as can be seen from Table 1, adopt the evil type puerperal general pain for the treatment of by Chinese herbs sense of the present invention, on therapeutic effect, there is significant improvement with respect to matched group; As can be seen from Table 2, adopt the evil type puerperal general pain for the treatment of by Chinese herbs sense of the present invention, with respect to matched group, treating significantly shortening on the course for the treatment of.
Four groups, table 1 is treated respectively Clinical efficacy comparison example after 1 month
Group Number of cases Recovery from illness Effective Effectively Invalid Total effective rate
Decoction treatment group 26 22 2 2 0 100%
Lotion for treatment group 28 20 4 4 0 100%
Capsule treatment group 28 24 2 2 0 100%
Matched group 28 16 5 4 3 89.3%
Four groups, table 2 is treated respectively recovery from illness and effective number and time comparative example (%) after 1 month
Group Number of cases 1-10 days 11-20 days 21-30 days
Decoction treatment group 24 4(16.7%) 14(58.3%) 6(25.0%)
Lotion for treatment group 24 5(20.8%) 14(58.3%) 5(20.8%)
Capsule treatment group 26 6(23.1%) 15(57.7%) 5(19.2%)
Matched group 21 2(9.5%) 6(28.6%) 13(61.9%)
Known according to the clinical statistics in above table, that Chinese medicine provided by the invention has is rapid-action, effective percentage is high, determined curative effect, safe, the advantage that has no side effect; To the recovery from illness of decoction treatment group and 24 effective examples, lotion for treatment group is fully recovered and 24 effective examples simultaneously, the recovery from illness of capsule treatment group and 26 effective examples, and matched group is fully recovered and 21 effective routine patients follow up a case by regular visits to 2 years, result statistics:
Decoction treatment group is cured and 24 effective examples, and 22 examples of recovery from illness are without recurrence, and 2 effective routine patients are without recurrence, and relapse rate is 0%;
Lotion for treatment group is cured and 24 effective examples, and 20 examples of recovery from illness are without recurrence, and 4 effective routine patients are without recurrence, and relapse rate is 0%;
Capsule treatment group is cured and 26 effective examples, and 24 examples of recovery from illness are without recurrence, and 2 effective routine patients are without recurrence, and relapse rate is 0%;
Western medicine group is cured and 21 effective routine patients, and 16 examples of recovery from illness, without recurrence, recur 2 examples in 5 effective routine patients, and relapse rate is 9.5%.
Model case:
Patient's first, female, 32 years old, in June, 2012 was medical.Patient's March front 2 tire natural labor 1 boy babies, lochia is clean January, existing suckling does not turn through, January in puerperal and remainingly occurs two upper limb because suffering from cold and take on back pain, does not take notice of.After gradually increase the weight of, arthralgia all over, activities adverse, white and thin fur, thready and stringy pulse.Auxiliary examination: anti-" O " and Rheumatoid antibody are normal, and X line is taken the photograph sheet sclerotin no abnormality seen.This group is got rid of the illness such as rheumatism, rheumatoid, osteoarthritis, local without red and swollen scorching hot.Tcm diagnosis is puerperal general pain, the dialectical evil type of sense that belongs to.After patient takes 5 doses of the decoctions of embodiment 1, symptom subtracts greatly, and after 2 weeks, whole body pain disappear.Drug withdrawal after 19 doses, follows up a case by regular visits to not recurrence in 2 years.
 
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (9)

1. treat the Chinese medicine of the evil type puerperal general pain of sense for one kind, it is characterized in that, comprise following raw medicinal material: Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis, Fructus Liquidambaris, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Semen Trigonellae, Cortex schefflerae octophyllae, Rhizoma Humatae Tyermanni, Cortex erythrinae, Colla cornus cervi and Semen Castaneae.
2. Chinese medicine according to claim 1, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Herba Schizonepetae 22-33 part, Rhizoma Et Radix Notopterygii 14-29 part, Radix Saposhnikoviae 17-33 part, Radix Angelicae Dahuricae 22-37 part, Rhizoma Ligustici 19-35 part, Bulbus Allii Fistulosi 24-38 part, Ramulus et Folium Tamaricis 20-34 part, Herba Lycopodii 15-32 part, Herba Aristolochiae Mollissimae 11-25 part, Caulis Sinomenii 14-31 part, Radix Morindae Officinalis 12-26 part, Fructus Liquidambaris 20-36 part, Caulis Trachelospermi 15-28 part, Caulis Spatholobi 14-32 part, Flos Carthami 16-29 part, Rhizoma Chuanxiong 19-31 part, Rhizoma Corydalis 4-10 part, Rhizoma Curcumae Longae 8-19 part, Semen Vaccariae 13-28 part, Radix Codonopsis 16-37 part, Radix Astragali 24-35 part, Rhizoma Dioscoreae 13-24 part, Radix Glycyrrhizae 18-31 part, Radix Rhodiolae 19-31 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-10 part, Semen Trigonellae 13-30 part, Cortex schefflerae octophyllae 27-42 part, Rhizoma Humatae Tyermanni 16-27 part, Cortex erythrinae 12-27 part, Colla cornus cervi 12-28 part and Semen Castaneae 30-41 part.
3. Chinese medicine according to claim 1 and 2, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Herba Schizonepetae 23-31 part, Rhizoma Et Radix Notopterygii 16-27 part, Radix Saposhnikoviae 19-30 part, Radix Angelicae Dahuricae 25-33 part, Rhizoma Ligustici 20-34 part, Bulbus Allii Fistulosi 26-36 part, Ramulus et Folium Tamaricis 22-32 part, Herba Lycopodii 17-29 part, Herba Aristolochiae Mollissimae 15-25 part, Caulis Sinomenii 18-27 part, Radix Morindae Officinalis 14-24 part, Fructus Liquidambaris 20-32 part, Caulis Trachelospermi 17-26 part, Caulis Spatholobi 18-30 part, Flos Carthami 16-23 part, Rhizoma Chuanxiong 19-29 part, Rhizoma Corydalis 7-10 part, Rhizoma Curcumae Longae 9-18 part, Semen Vaccariae 15-24 part, Radix Codonopsis 18-34 part, Radix Astragali 26-31 part, Rhizoma Dioscoreae 15-21 part, Radix Glycyrrhizae 19-30 part, Radix Rhodiolae 23-30 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 6-9 part, Semen Trigonellae 14-28 part, Cortex schefflerae octophyllae 27-35 part, Rhizoma Humatae Tyermanni 16-23 part, Cortex erythrinae 12-22 part, Colla cornus cervi 12-20 part and Semen Castaneae 30-36 part.
4. according to the arbitrary described Chinese medicine of claim 1-3, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: 23 parts of Herba Schizonepetae, 19 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 28 parts of the Radixs Angelicae Dahuricae, 20 parts of Rhizoma Ligusticis, 36 parts of Bulbus Allii Fistulosi, 22 parts of Ramulus et Folium Tamariciss, 25 parts of Herba Lycopodiis, 15 parts of Herba Aristolochiae Mollissimaes, 26 parts of Caulis Sinomeniis, 14 parts of Radix Morindae Officinaliss, 29 parts of Fructus Liquidambaris, 17 parts of Caulis Trachelospermis, 28 parts of Caulis Spatholobis, 16 parts, Flos Carthami, 22 parts of Rhizoma Chuanxiongs, 7 parts of Rhizoma Corydalis, 11 parts, Rhizoma Curcumae Longae, 15 parts of Semen Vaccariae, 24 parts of Radix Codonopsis, 31 parts of the Radixs Astragali, 17 parts of Rhizoma Dioscoreaes, 19 parts, Radix Glycyrrhizae, 25 parts of Radix Rhodiolaes, 6 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 18 parts of Semen Trigonellaes, 27 parts of Cortex schefflerae octophyllaes, 18 parts of Rhizoma Humatae Tyermannis, 12 parts of Cortex erythrinaes, 30 parts, 19 parts of Colla cornus cervis and Semen Castaneae.
5. according to the arbitrary described Chinese medicine of claim 1-3, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: 31 parts of Herba Schizonepetae, 27 parts of Rhizoma Et Radix Notopterygiis, 24 parts of Radix Saposhnikoviaes, 33 parts of the Radixs Angelicae Dahuricae, 34 parts of Rhizoma Ligusticis, 30 parts of Bulbus Allii Fistulosi, 32 parts of Ramulus et Folium Tamariciss, 29 parts of Herba Lycopodiis, 25 parts of Herba Aristolochiae Mollissimaes, 27 parts of Caulis Sinomeniis, 24 parts of Radix Morindae Officinaliss, 32 parts of Fructus Liquidambaris, 26 parts of Caulis Trachelospermis, 30 parts of Caulis Spatholobis, 23 parts, Flos Carthami, 19 parts of Rhizoma Chuanxiongs, 9 parts of Rhizoma Corydalis, 9 parts, Rhizoma Curcumae Longae, 24 parts of Semen Vaccariae, 18 parts of Radix Codonopsis, 26 parts of the Radixs Astragali, 21 parts of Rhizoma Dioscoreaes, 30 parts, Radix Glycyrrhizae, 30 parts of Radix Rhodiolaes, 9 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 28 parts of Semen Trigonellaes, 35 parts of Cortex schefflerae octophyllaes, 23 parts of Rhizoma Humatae Tyermannis, 22 parts of Cortex erythrinaes, 36 parts, 20 parts of Colla cornus cervis and Semen Castaneae.
6. according to the arbitrary described Chinese medicine of claim 1-3, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: 27 parts of Herba Schizonepetae, 16 parts of Rhizoma Et Radix Notopterygiis, 19 parts of Radix Saposhnikoviaes, 25 parts of the Radixs Angelicae Dahuricae, 32 parts of Rhizoma Ligusticis, 26 parts of Bulbus Allii Fistulosi, 27 parts of Ramulus et Folium Tamariciss, 17 parts of Herba Lycopodiis, 21 parts of Herba Aristolochiae Mollissimaes, 18 parts of Caulis Sinomeniis, 18 parts of Radix Morindae Officinaliss, 20 parts of Fructus Liquidambaris, 20 parts of Caulis Trachelospermis, 18 parts of Caulis Spatholobis, 18 parts, Flos Carthami, 29 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Corydalis, 18 parts, Rhizoma Curcumae Longae, 16 parts of Semen Vaccariae, 34 parts of Radix Codonopsis, 29 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 27 parts, Radix Glycyrrhizae, 23 parts of Radix Rhodiolaes, 7 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)s, 14 parts of Semen Trigonellaes, 34 parts of Cortex schefflerae octophyllaes, 16 parts of Rhizoma Humatae Tyermannis, 14 parts of Cortex erythrinaes, 33 parts, 12 parts of Colla cornus cervis and Semen Castaneae.
7. according to the arbitrary described Chinese medicine of claim 1-6, it is characterized in that, when the dosage form of described Chinese medicine is decoction, its preparation method comprises the following steps:
Step 1: described raw medicinal material is mixed and puts into purple casserole, add clear water, soaked medical material upper surface 2-5cm to clear water, soak 3-10 hour;
Step 2: purple casserole is placed in to fire upper, after intense fire boils, uses slow fire instead and decoct slowly 30-50 minute, filter, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added to clear water again, soaked medical material upper surface 2-3cm to clear water, soak 3-10 hour;
Step 4: purple casserole is placed in to fire upper, after intense fire boils, uses slow fire instead and decoct slowly 25-35 minute, filter, obtain filtrate b, filtrate a and filtrate b are mixed.
8. according to the arbitrary described Chinese medicine of claim 1-6, it is characterized in that, when the dosage form of described Chinese medicine is lotion, its preparation method comprises the following steps:
The first step, described raw medicinal material is mixed in proportion, put into super micron mill and be ground into the mixed powder that the micron particles of 0.1~10 μ m volume average particle size and particle diameter are less than the nano-scale particle composition of 0.1 μ m volume average particle size, described mixed powder powder rate be at least 95%;
Second step, the ethanol that to add with respect to the determining alcohol of 3~5 times of the quality of described mixed powder in the mixed powder obtaining in the first step be 85%~95%, stirring and dissolving obtains alcoholic solution, alcoholic solution is left standstill to 24~36 hours under the condition of 5 DEG C~10 DEG C, adopt the speed slowly percolation of percolation with 1~2ml per minute, collect percolate, concentrate and be dried, and put into super micron mill at this and pulverize 40~60 minutes, the micron particles of acquisition 0.1~10 μ m volume average particle size and particle diameter are less than the mixed powder of the nano-scale particle composition of 0.1 μ m volume average particle size, the powder rate that obtains of described mixed powder is at least 95%,
The 3rd step, adds deionized water with respect to mixed powder quality 2~3 times in the mixed powder obtaining at second step, decocts 2~4 hours, filters, and obtains medicine juice.
9. according to the arbitrary described Chinese medicine of claim 1-6, it is characterized in that, when the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:
The first step is mixed Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Bulbus Allii Fistulosi, Ramulus et Folium Tamaricis, Herba Lycopodii, Herba Aristolochiae Mollissimae, Caulis Sinomenii, Radix Morindae Officinalis and Fructus Liquidambaris in described ratio, add the water extraction volatile oil with respect to 4~6 times, mixture, by the volatile oil beta-cyclodextrin inclusion compound obtaining, the mass ratio of volatile oil and beta-schardinger dextrin-is 1: 3~6, stir 60 minutes~90 minutes, 30 DEG C~50 DEG C of temperature, obtain volatile oil clathrate compound, for subsequent use; The clear paste that while separately aqueous extract being concentrated into 60 DEG C, relative density is 1.15~1.17;
Second step, Caulis Trachelospermi, Caulis Spatholobi, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Curcumae Longae, Semen Vaccariae, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Rhodiolae and Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) are mixed in described ratio, the alcohol reflux that to add with respect to 5~8 times, mixture amount determining alcohols be 75%~90% 3~5 times, each 2~3 hours, filter respectively, each time filtrate merges, and reclaims ethanol, the clear paste that while being concentrated into 60 DEG C, relative density is 1.20~1.22, for subsequent use;
The 3rd step, will remain described raw medicinal material and mix in described ratio, add with respect to 8~10 times of water gagings of mixture, boil 6~8 hours, filter the clear paste that while being concentrated into 60 DEG C, relative density is 1.28~1.30;
The 4th step, mixes the clear paste of the first step, second step, the 3rd step, and 60 DEG C~70 DEG C reduced vacuum are dry, and powder gets dry extract;
The 5th step, dried cream powder described in volatile oil clathrate compound described in the first step and the 4th step is fully mixed, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 5~7 weight portion carboxymethyl starch sodium, 5~50 weight portion starch mix homogeneously, adding 150~200 weight portion determining alcohols is 80%~90% alcohol granulation, dry, granulate, add subsequently the mixture with respect to volatile oil clathrate compound described in 100 weight portions and dried cream powder, 3~5 weight portion magnesium stearate, then pack in gelatine capsule.
CN201410416060.1A 2014-08-22 2014-08-22 Traditional Chinese medicine for treating pantalgia after childbirth caused by exogenous pathogen and preparation method thereof Pending CN104127831A (en)

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CN105056061A (en) * 2015-08-03 2015-11-18 吕淑霞 Traditional Chinese medicine composition for treating postpartum wind-cold
CN105596754A (en) * 2016-01-28 2016-05-25 济南思拓新源医药科技有限公司 Traditional Chinese medicine for treating blood deficiency type postpartum pain of body and preparing method thereof
CN105998555A (en) * 2016-07-18 2016-10-12 夏雪飞 Traditional Chinese medicine pill applied to postpartum arthralgia relief and nursing, and preparation method of traditional Chinese medicine pill

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105056061A (en) * 2015-08-03 2015-11-18 吕淑霞 Traditional Chinese medicine composition for treating postpartum wind-cold
CN105596754A (en) * 2016-01-28 2016-05-25 济南思拓新源医药科技有限公司 Traditional Chinese medicine for treating blood deficiency type postpartum pain of body and preparing method thereof
CN105998555A (en) * 2016-07-18 2016-10-12 夏雪飞 Traditional Chinese medicine pill applied to postpartum arthralgia relief and nursing, and preparation method of traditional Chinese medicine pill

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Application publication date: 20141105