CN103340899A - 包括三氧化二砷的口服组合物的制剂及其使用方法 - Google Patents

包括三氧化二砷的口服组合物的制剂及其使用方法 Download PDF

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Publication number
CN103340899A
CN103340899A CN2013101363192A CN201310136319A CN103340899A CN 103340899 A CN103340899 A CN 103340899A CN 2013101363192 A CN2013101363192 A CN 2013101363192A CN 201310136319 A CN201310136319 A CN 201310136319A CN 103340899 A CN103340899 A CN 103340899A
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CN
China
Prior art keywords
arsenic trioxide
solution
arsenic
oral
leukemia
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Pending
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CN2013101363192A
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English (en)
Chinese (zh)
Inventor
C·R·库马纳
Y·邝
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Versitech Ltd
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Versitech Ltd
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Publication of CN103340899A publication Critical patent/CN103340899A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/36Arsenic; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2013101363192A 2002-10-09 2003-10-08 包括三氧化二砷的口服组合物的制剂及其使用方法 Pending CN103340899A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41720002P 2002-10-09 2002-10-09
US60/417,200 2002-10-09
US48301403P 2003-06-25 2003-06-25
US60/483,014 2003-06-25

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN 200380105498 Division CN1723029A (zh) 2002-10-09 2003-10-08 包括三氧化二砷的口服组合物的制剂及其使用方法

Publications (1)

Publication Number Publication Date
CN103340899A true CN103340899A (zh) 2013-10-09

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ID=32096185

Family Applications (1)

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CN2013101363192A Pending CN103340899A (zh) 2002-10-09 2003-10-08 包括三氧化二砷的口服组合物的制剂及其使用方法

Country Status (6)

Country Link
US (1) US7521071B2 (enExample)
EP (2) EP3106169B1 (enExample)
JP (1) JP4786341B2 (enExample)
CN (1) CN103340899A (enExample)
AU (1) AU2003271510A1 (enExample)
WO (1) WO2004032822A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10111836B2 (en) 2015-02-01 2018-10-30 Orsenix Holdings Bv High surface-area lyophilized compositions comprising arsenic for oral administration in patients
CN111184703A (zh) * 2018-11-15 2020-05-22 哈尔滨医大药业股份有限公司 三氧化二砷缓释小丸及其制备方法

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1044559C (zh) * 1995-08-23 1999-08-11 哈尔滨医科大学附属第一医院 抗白血病、肝癌、淋巴瘤注射液
US20080166425A1 (en) * 2002-10-09 2008-07-10 The University Of Hong Kong Method for inhibiting cancer using arsenic trioxide
US20080089949A1 (en) * 2006-10-13 2008-04-17 Yok-Lam Kwong Method for treating cancer using oral arsenic trioxide
US7521071B2 (en) * 2002-10-09 2009-04-21 Versitech Limited Formulation of oral compositions comprising arsenic trioxide and methods of use thereof
US8906422B2 (en) * 2002-10-09 2014-12-09 The University Of Hong Kong Method for inhibiting cancer using arsenic trioxide
US20110008327A1 (en) * 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US8435959B2 (en) 2004-03-29 2013-05-07 University Of South Florida Effective treatment of tumors and cancer with triciribine and related compounds
US20100173864A1 (en) 2004-03-29 2010-07-08 Cheng Jin Q Compositions including triciribine and one or more platinum compounds and methods of use thereof
US20100009928A1 (en) * 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and taxanes and methods of use thereof
US20100028339A1 (en) 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
CN1870631B (zh) * 2005-11-11 2010-04-14 华为技术有限公司 媒体网关的门控方法
WO2008046299A1 (en) * 2006-10-11 2008-04-24 The University Of Hong Kong Method for inhibiting cancer using arsenic trioxide
US8795738B2 (en) 2009-11-12 2014-08-05 Board Of Regents Of The University Of Texas System Use of arsenic for cancer therapy protection
US8834938B2 (en) 2011-05-18 2014-09-16 Board Of Regents Of The University Of Texas System Use of arsenic for cancer therapy protection
CN103142648B (zh) * 2011-12-07 2015-04-15 浙江中医药大学 一种砷化合物溶液及其制备的包载砷化合物的白蛋白纳米粒和冻干制剂
ES2641847T3 (es) 2012-09-20 2017-11-14 Yogesh Narayan BENDALE Proceso para biosintetizar nanotrióxido de arsénico y su uso en el tratamiento de enfermedades que incluyen el cáncer
WO2014151317A1 (en) * 2013-03-15 2014-09-25 Rush University Medical Center Methods for treating cancer
SG11201706150QA (en) 2015-01-29 2017-08-30 Eupharma Pty Ltd Compositions containing arsenic and their use in methods of treatment
KR102015858B1 (ko) * 2015-10-23 2019-08-30 손영태 법제된 비상을 함유하는 면역력 증강을 위한 약학적 조성물
IL265986B (en) 2016-12-01 2022-09-01 Eupharma Pty Ltd Pharmaceutical composition comprising an alkali metal and/or an alkaline earth metal diarsenic (iii) tetraoxide and uses thereof
US11583552B2 (en) 2021-02-17 2023-02-21 Manoj Maniar Pharmaceutical formulation of arsenic trioxide
EP4455672A1 (en) 2023-04-26 2024-10-30 Medsenic Method and kit for diagnosing and monitoring chronic graft-versus-host disease (cgvhd) using particular cytokine biomarkers
WO2025172482A1 (en) 2024-02-14 2025-08-21 Institut Gustave Roussy Oral composition of arsenic trioxide for cancer treatment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1285743A (zh) * 1997-11-10 2001-02-28 斯隆-凯特林纪念癌症中心 三氧化二砷制剂生产法及用三氧化二砷或米拉索普治癌法
CN1370540A (zh) * 2001-02-15 2002-09-25 暨南大学 治疗恶性淋巴瘤的药物及其配制方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875451B2 (en) * 1997-10-15 2005-04-05 Polarx Biopharmaceuticals Inc. Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
FR2786103A1 (fr) * 1998-10-30 2000-05-26 Assist Publ Hopitaux De Paris Utilisation de trioxyde d'arsenic pour la preparation d'un medicament destine a traiter les affections neoplastiques du tissu hematopoietique chez un mammifere et nouvelle composition pharmaceutique
US7521071B2 (en) * 2002-10-09 2009-04-21 Versitech Limited Formulation of oral compositions comprising arsenic trioxide and methods of use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1285743A (zh) * 1997-11-10 2001-02-28 斯隆-凯特林纪念癌症中心 三氧化二砷制剂生产法及用三氧化二砷或米拉索普治癌法
CN1370540A (zh) * 2001-02-15 2002-09-25 暨南大学 治疗恶性淋巴瘤的药物及其配制方法

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10111836B2 (en) 2015-02-01 2018-10-30 Orsenix Holdings Bv High surface-area lyophilized compositions comprising arsenic for oral administration in patients
US10272045B2 (en) 2015-02-01 2019-04-30 Orsenix Holdings Bv High surface-area lyophilized compositions comprising arsenic for oral administration in patients
US10653628B2 (en) 2015-02-01 2020-05-19 Orsenix Holdings Bv High surface-area lyophilized compositions comprising arsenic for oral administration in patients
US12364664B2 (en) 2015-02-01 2025-07-22 Quetzal Therapeutics, Llc Lyophilized compositions comprising arsenic
CN111184703A (zh) * 2018-11-15 2020-05-22 哈尔滨医大药业股份有限公司 三氧化二砷缓释小丸及其制备方法

Also Published As

Publication number Publication date
EP1562616A4 (en) 2008-12-17
EP3106169B1 (en) 2021-05-19
WO2004032822A3 (en) 2004-12-29
EP3106169A1 (en) 2016-12-21
AU2003271510A1 (en) 2004-05-04
US7521071B2 (en) 2009-04-21
JP2006503109A (ja) 2006-01-26
US20040126434A1 (en) 2004-07-01
JP4786341B2 (ja) 2011-10-05
EP1562616A2 (en) 2005-08-17
AU2003271510A8 (en) 2004-05-04
EP1562616B1 (en) 2016-06-01
WO2004032822A2 (en) 2004-04-22

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Application publication date: 20131009

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