AU2003271510A1 - Formulation of oral compositions comprising arsenic trioxide and methods of use thereof - Google Patents
Formulation of oral compositions comprising arsenic trioxide and methods of use thereofInfo
- Publication number
- AU2003271510A1 AU2003271510A1 AU2003271510A AU2003271510A AU2003271510A1 AU 2003271510 A1 AU2003271510 A1 AU 2003271510A1 AU 2003271510 A AU2003271510 A AU 2003271510A AU 2003271510 A AU2003271510 A AU 2003271510A AU 2003271510 A1 AU2003271510 A1 AU 2003271510A1
- Authority
- AU
- Australia
- Prior art keywords
- formulation
- methods
- oral compositions
- arsenic trioxide
- trioxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000203 mixture Substances 0.000 title 2
- HJTAZXHBEBIQQX-UHFFFAOYSA-N 1,5-bis(chloromethyl)naphthalene Chemical compound C1=CC=C2C(CCl)=CC=CC2=C1CCl HJTAZXHBEBIQQX-UHFFFAOYSA-N 0.000 title 1
- GOLCXWYRSKYTSP-UHFFFAOYSA-N arsenic trioxide Inorganic materials O1[As]2O[As]1O2 GOLCXWYRSKYTSP-UHFFFAOYSA-N 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/36—Arsenic; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41720002P | 2002-10-09 | 2002-10-09 | |
| US60/417,200 | 2002-10-09 | ||
| US48301403P | 2003-06-25 | 2003-06-25 | |
| US60/483,014 | 2003-06-25 | ||
| PCT/CN2003/000843 WO2004032822A2 (en) | 2002-10-09 | 2003-10-08 | Formulation of oral compositions comprising arsenic trioxide and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003271510A1 true AU2003271510A1 (en) | 2004-05-04 |
| AU2003271510A8 AU2003271510A8 (en) | 2004-05-04 |
Family
ID=32096185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003271510A Abandoned AU2003271510A1 (en) | 2002-10-09 | 2003-10-08 | Formulation of oral compositions comprising arsenic trioxide and methods of use thereof |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7521071B2 (enExample) |
| EP (2) | EP3106169B1 (enExample) |
| JP (1) | JP4786341B2 (enExample) |
| CN (1) | CN103340899A (enExample) |
| AU (1) | AU2003271510A1 (enExample) |
| WO (1) | WO2004032822A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1044559C (zh) * | 1995-08-23 | 1999-08-11 | 哈尔滨医科大学附属第一医院 | 抗白血病、肝癌、淋巴瘤注射液 |
| US20080166425A1 (en) * | 2002-10-09 | 2008-07-10 | The University Of Hong Kong | Method for inhibiting cancer using arsenic trioxide |
| US20080089949A1 (en) * | 2006-10-13 | 2008-04-17 | Yok-Lam Kwong | Method for treating cancer using oral arsenic trioxide |
| US7521071B2 (en) * | 2002-10-09 | 2009-04-21 | Versitech Limited | Formulation of oral compositions comprising arsenic trioxide and methods of use thereof |
| US8906422B2 (en) * | 2002-10-09 | 2014-12-09 | The University Of Hong Kong | Method for inhibiting cancer using arsenic trioxide |
| US20110008327A1 (en) * | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
| US8435959B2 (en) | 2004-03-29 | 2013-05-07 | University Of South Florida | Effective treatment of tumors and cancer with triciribine and related compounds |
| US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| US20100009928A1 (en) * | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
| US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
| US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
| CN1870631B (zh) * | 2005-11-11 | 2010-04-14 | 华为技术有限公司 | 媒体网关的门控方法 |
| WO2008046299A1 (en) * | 2006-10-11 | 2008-04-24 | The University Of Hong Kong | Method for inhibiting cancer using arsenic trioxide |
| US8795738B2 (en) | 2009-11-12 | 2014-08-05 | Board Of Regents Of The University Of Texas System | Use of arsenic for cancer therapy protection |
| US8834938B2 (en) | 2011-05-18 | 2014-09-16 | Board Of Regents Of The University Of Texas System | Use of arsenic for cancer therapy protection |
| CN103142648B (zh) * | 2011-12-07 | 2015-04-15 | 浙江中医药大学 | 一种砷化合物溶液及其制备的包载砷化合物的白蛋白纳米粒和冻干制剂 |
| ES2641847T3 (es) | 2012-09-20 | 2017-11-14 | Yogesh Narayan BENDALE | Proceso para biosintetizar nanotrióxido de arsénico y su uso en el tratamiento de enfermedades que incluyen el cáncer |
| WO2014151317A1 (en) * | 2013-03-15 | 2014-09-25 | Rush University Medical Center | Methods for treating cancer |
| SG11201706150QA (en) | 2015-01-29 | 2017-08-30 | Eupharma Pty Ltd | Compositions containing arsenic and their use in methods of treatment |
| US10111836B2 (en) | 2015-02-01 | 2018-10-30 | Orsenix Holdings Bv | High surface-area lyophilized compositions comprising arsenic for oral administration in patients |
| KR102015858B1 (ko) * | 2015-10-23 | 2019-08-30 | 손영태 | 법제된 비상을 함유하는 면역력 증강을 위한 약학적 조성물 |
| IL265986B (en) | 2016-12-01 | 2022-09-01 | Eupharma Pty Ltd | Pharmaceutical composition comprising an alkali metal and/or an alkaline earth metal diarsenic (iii) tetraoxide and uses thereof |
| CN111184703B (zh) * | 2018-11-15 | 2023-03-28 | 哈尔滨医大药业股份有限公司 | 三氧化二砷缓释小丸及其制备方法 |
| US11583552B2 (en) | 2021-02-17 | 2023-02-21 | Manoj Maniar | Pharmaceutical formulation of arsenic trioxide |
| EP4455672A1 (en) | 2023-04-26 | 2024-10-30 | Medsenic | Method and kit for diagnosing and monitoring chronic graft-versus-host disease (cgvhd) using particular cytokine biomarkers |
| WO2025172482A1 (en) | 2024-02-14 | 2025-08-21 | Institut Gustave Roussy | Oral composition of arsenic trioxide for cancer treatment |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875451B2 (en) * | 1997-10-15 | 2005-04-05 | Polarx Biopharmaceuticals Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| ES2395515T3 (es) * | 1997-11-10 | 2013-02-13 | Memorial Sloan Kettering Cancer Center | Trióxido de arsénico para uso en el tratamiento de la leucemia |
| FR2786103A1 (fr) * | 1998-10-30 | 2000-05-26 | Assist Publ Hopitaux De Paris | Utilisation de trioxyde d'arsenic pour la preparation d'un medicament destine a traiter les affections neoplastiques du tissu hematopoietique chez un mammifere et nouvelle composition pharmaceutique |
| CN1176665C (zh) * | 2001-02-15 | 2004-11-24 | 暨南大学 | 治疗恶性淋巴瘤的药物及其配制方法 |
| US7521071B2 (en) * | 2002-10-09 | 2009-04-21 | Versitech Limited | Formulation of oral compositions comprising arsenic trioxide and methods of use thereof |
-
2003
- 2003-09-23 US US10/669,869 patent/US7521071B2/en not_active Expired - Lifetime
- 2003-10-08 CN CN2013101363192A patent/CN103340899A/zh active Pending
- 2003-10-08 AU AU2003271510A patent/AU2003271510A1/en not_active Abandoned
- 2003-10-08 JP JP2005500968A patent/JP4786341B2/ja not_active Expired - Lifetime
- 2003-10-08 EP EP16167636.6A patent/EP3106169B1/en not_active Expired - Lifetime
- 2003-10-08 EP EP03753241.3A patent/EP1562616B1/en not_active Expired - Lifetime
- 2003-10-08 WO PCT/CN2003/000843 patent/WO2004032822A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1562616A4 (en) | 2008-12-17 |
| EP3106169B1 (en) | 2021-05-19 |
| WO2004032822A3 (en) | 2004-12-29 |
| EP3106169A1 (en) | 2016-12-21 |
| US7521071B2 (en) | 2009-04-21 |
| JP2006503109A (ja) | 2006-01-26 |
| US20040126434A1 (en) | 2004-07-01 |
| JP4786341B2 (ja) | 2011-10-05 |
| EP1562616A2 (en) | 2005-08-17 |
| CN103340899A (zh) | 2013-10-09 |
| AU2003271510A8 (en) | 2004-05-04 |
| EP1562616B1 (en) | 2016-06-01 |
| WO2004032822A2 (en) | 2004-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |