CN103340894A - Preparation method of capsule capable of enhancing bone density - Google Patents
Preparation method of capsule capable of enhancing bone density Download PDFInfo
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- CN103340894A CN103340894A CN2013102434119A CN201310243411A CN103340894A CN 103340894 A CN103340894 A CN 103340894A CN 2013102434119 A CN2013102434119 A CN 2013102434119A CN 201310243411 A CN201310243411 A CN 201310243411A CN 103340894 A CN103340894 A CN 103340894A
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Abstract
The invention relates to a preparation method of a capsule capable of enhancing bone density. The capsule capable of enhancing bone density is obtained by the steps of taking any ingredient of a formula, mixing the ingredient with vitamin D, grinding to uniform, adding residual ingredients, mixing, pelletizing the mixture, drying, adding a proper amount of auxiliary materials, mixing uniformly, loading into capsules, carrying out quality detection and packaging. The capsule has a function of enhancing bone density, can prevent rachitis, tetany and chondropathy, is convenient for use, is a clinically popular, safe, stable and effective health-care product, and is an ideal product for modern pharmaceutical companies.
Description
Technical field
The present invention relates to the processing technology technical field of Chinese medicine capsule, relate in particular to the preparation method that increases the bone density capsule.
Background technology
Show through modern medicine study, normal person's all ages and classes section bone mineral content difference, the different human different health indicators of bone mineral content reaction, with the important indicator of bone density as the bone strength evaluation, with gram/every square centimeter of expression, be an absolute value, reflection osteoporosis degree, the important evidence of prediction fracture risk.The D-glucosamine hydrochlorate is from natural chitin extraction in this prescription, it is a kind of marine biological preparation, can promote the synthetic of human body mucopolysaccharide, improve the viscosity of knuckle synovia, can improve the metabolism of articular cartilage, also be that medical circle is considered as the only material that can at all treat joint disease up to now, and itself and chondroitin sulfate are used, can promote the effect of regenerating bone or cartilage, can be from improve the joint problem at all; Calcium is the Source of life of human body, is the abundantest inorganic elements of body burden, and total amount surpasses 1 kilogram, and the good reputation of human body " biological element " is arranged, and the calcium in the human body 99% is deposited in skeleton and the tooth, promotes its growth promoter, keeps its form and hardness; Vitamin D is the steroid derivant, can improve human body to the absorption of calcium, phosphorus, promotes growth and skeleton calcification, promotes tooth sound.Human body is called antirachitic vitamin again if the D that is deficient in vitamin can cause rickets, tetany and osteomalacia.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, a kind of preparation method that increases the bone density capsule is provided, to satisfy society need better.
The preparation method of increase bone density capsule of the present invention comprises the steps:
One, takes by weighing each raw material by following prescription
Increase the bone density capsule to make 1000:
D-glucosamine hydrochlorate 80g-170g
Calcium 80g-240g
Vitamin D 750 μ g-4780 μ g
Chondroitin sulfate 80g-149g
Adjuvant 50 g-100 g
Described adjuvant can be one or more in microcrystalline Cellulose, polyvinylpolypyrrolidone, carboxymethylstach sodium, 30 POVIDONE K 30 BP/USP 30, micropowder silica gel, lactose, low-substituted hydroxypropyl cellulose, starch, dextrin, the magnesium stearate.
Two, increase the bone density capsule with above-mentioned supplementary material preparation
Method one is got D-glucosamine hydrochlorate 10g-20g and vitamin D mixed grinding to mixing by above-mentioned prescription, add remaining D-glucosamine hydrochlorate and calcium, chondroitin sulfate powder mixing again, granulate, dry, add after the auxiliary materials and mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule;
Method two is got chondroitin sulfate 10g-20g and vitamin D mixed grinding to mixing by above-mentioned prescription, add remaining chondroitin sulfate and calcium, D-glucosamine hydrochlorate powder mixing again, granulate, dry, add after the auxiliary materials and mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule;
Method three is got calcium 10g-20g and vitamin D mixed grinding to mixing by above-mentioned prescription, adds remaining calcium and chondroitin sulfate, D-glucosamine hydrochlorate powder mixing again, granulates, drying, add at last after the auxiliary materials and mixing encapsulated, quality inspection, packing, namely getting increases the bone density capsule.
Beneficial effect of the present invention: this technology is reasonable, production is easy, this product has the function that increases bone density, can be used for preventing rickets, tetany and osteomalacia, and because of capsule carry, easy to use, be clinical welcome, safety, stable, effective health product are the desirable products of modern pharmaceutical enterprise.And the qualitative, quantitative control method that science is arranged makes the quality of product secure.
The specific embodiment
Example 1:
Get D-glucosamine hydrochlorate 10g and vitamin D 3000 μ g mixed grindings to mixing, add again remaining D-glucosamine hydrochlorate 5g respectively with calcium 180g, chondroitin sulfate powder 120g mixing, granulate, dry, add behind the magnesium stearate 80g mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule.
Example 2:
Get chondroitin sulfate 80g and vitamin D 2800 μ g mixed grindings to mixing, add again remaining chondroitin sulfate 20g respectively with calcium 200g, D-glucosamine hydrochlorate 18g powder mixing, granulate, dry, add behind the magnesium stearate 100g mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule.
Example 3:
Get calcium 150g and vitamin D 3500 μ g mixed grindings to mixing, add again remaining calcium 30g respectively with chondroitin sulfate 120g, D-glucosamine hydrochlorate 16g powder mixing, granulate, dry, add behind the magnesium stearate 100g mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule.
Claims (1)
1. preparation method that increases the bone density capsule is characterized in that:
(1) takes by weighing each supplementary material by following prescription
Increase the bone density capsule to make 1000:
D-glucosamine hydrochlorate 80g-170g
Calcium 80g-240g
Vitamin D 750 μ g-4780 μ g
Chondroitin sulfate 80g-149g
Adjuvant 50 g-100 g
Described adjuvant can be one or more in microcrystalline Cellulose, polyvinylpolypyrrolidone, carboxymethylstach sodium, 30 POVIDONE K 30 BP/USP 30, micropowder silica gel, lactose, low-substituted hydroxypropyl cellulose, starch, dextrin, the magnesium stearate;
(2) increase the bone density capsule with above-mentioned supplementary material preparation
Method one is got D-glucosamine hydrochlorate 10g-20g and vitamin D mixed grinding to mixing by above-mentioned prescription, add remaining D-glucosamine hydrochlorate and calcium, chondroitin sulfate powder mixing again, granulate, dry, add after the auxiliary materials and mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule;
Method two is got chondroitin sulfate 10g-20g and vitamin D mixed grinding to mixing by above-mentioned prescription, add remaining chondroitin sulfate and calcium, D-glucosamine hydrochlorate powder mixing again, granulate, dry, add after the auxiliary materials and mixing encapsulated at last, quality inspection, packing, namely getting increases the bone density capsule;
Method three is got calcium 10g-20g and vitamin D mixed grinding to mixing by above-mentioned prescription, adds remaining calcium and chondroitin sulfate, D-glucosamine hydrochlorate powder mixing again, granulates, drying, add at last after the auxiliary materials and mixing encapsulated, quality inspection, packing, namely getting increases the bone density capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013102434119A CN103340894A (en) | 2013-06-19 | 2013-06-19 | Preparation method of capsule capable of enhancing bone density |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2013102434119A CN103340894A (en) | 2013-06-19 | 2013-06-19 | Preparation method of capsule capable of enhancing bone density |
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| CN103340894A true CN103340894A (en) | 2013-10-09 |
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| CN2013102434119A Pending CN103340894A (en) | 2013-06-19 | 2013-06-19 | Preparation method of capsule capable of enhancing bone density |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104664402A (en) * | 2015-03-26 | 2015-06-03 | 江苏康缘药业股份有限公司 | Composition for increasing bone density and preparation method and application of composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904866A (en) * | 2010-09-07 | 2010-12-08 | 许阳 | Medicinal composition for treating osteoporosis and preparation method thereof |
| CN102224896A (en) * | 2011-05-13 | 2011-10-26 | 营养屋(成都)生物医药有限公司 | Health food for enhancing human immunity and increasing bone mineral density and preparation method thereof |
| CN102302116A (en) * | 2011-06-10 | 2012-01-04 | 营养屋(成都)生物医药有限公司 | Calcium supplementing and calcium locking health care food and preparation method thereof |
-
2013
- 2013-06-19 CN CN2013102434119A patent/CN103340894A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904866A (en) * | 2010-09-07 | 2010-12-08 | 许阳 | Medicinal composition for treating osteoporosis and preparation method thereof |
| CN102224896A (en) * | 2011-05-13 | 2011-10-26 | 营养屋(成都)生物医药有限公司 | Health food for enhancing human immunity and increasing bone mineral density and preparation method thereof |
| CN102302116A (en) * | 2011-06-10 | 2012-01-04 | 营养屋(成都)生物医药有限公司 | Calcium supplementing and calcium locking health care food and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104664402A (en) * | 2015-03-26 | 2015-06-03 | 江苏康缘药业股份有限公司 | Composition for increasing bone density and preparation method and application of composition |
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Application publication date: 20131009 |